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Top 15 Medical Startup Investors in South Africa in May 2025

Last updated: May 2025 A list of 15 angel investors and VC (Venture Capital) funds that invest in Medical startups based in South africa. We rank investors based on the number of investments they made in Medical companies from South africa. We update this investor list every month.

Top 15 Medical Startup Investors in South Africa in May 2025

Investor	Medical South Africa investments
HAVAÍC	2
54 Collective	2
AAIC Holdings	1
PayPal	1
Foreign & Commonwealth Office - UK	1
Goodwater Capital	1
PUSH Ventures	1
Jozi Angels	1
AngelHub Ventures	1
Ardent Capital	1
Enza Capital	1
WZ Capital	1
i-Cubed Capital	1
Growth Grid Venture Capital Partners	1
ASISA Enterprise Development Fund	1

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Investor list

HAVAÍC is an investment and advisory firm that specialises in early-stage, high-growth African businesses with proven concepts and global prospects, offering investment opportunities to sophisticated investors and international venture capital companies with an interest in Africa. As a complementary offering, HAVAÍC provides corporate advisory andcapital raising services to emerging, internationally scalable businesses.

Investment focus

Software, Health Care, FinTech
Seed, Funding Round, Series A
South Africa, United States, Kenya

Portfolio highlights

NjiaPay — Payments-as-a-Service platform that will streamline your operations and elevate your online payments across the African continent.
Talk360 — Talk360 is an easy-to-use calling app that helps people make affordable international calls to any mobile and landline number. They believe that reliable communication and digital services must be affordable and accessible to everyone, regardless of someone's background. Especially people in emerging countries in Africa, who often need theseservices the most, do not always have the necessary banking possibilities. To bridge this distance, Talk360 will launch the world's first single checkout platform for Africa. This platform will combine all locally available payment methods and currencies across Africa, together with over 1.25 million cash points of sales, and will eventually be available to other companies as well. This means that 500 million Africans will be able to purchase digital services they never had access to before.
Right Now Response — The future of repairs starts soon. Counting down to smarter tracking in 2025! There are perks to working 24/7, 365 days a year... Like launching the future of repairs ahead of schedule!

Building and scaling African tech startups with catalytic capital, value-add support and our global network.

Investment focus

Health Care, Information Technology, FinTech
Seed, Pre-Seed, Funding Round
Kenya, Nigeria, South Africa

Portfolio highlights

Billboxx — Enabling businesses pay and get paid twice as fast
Yeah — Yeah is a financial technology company that offers payment processing services while building a credit profile for the banked and unbanked.
Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.

AAIC Holdingsis engages in nurturing investments in emerging countries, consulting and M&A, management outsourcing and human capital.

Investment focus

Health Care, Medical, Apps
Seed, Series A, Funding Round
Togo, Nigeria, South Africa

Portfolio highlights

Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.

PayPal has remained at the forefront of the digital payment revolution for more than 20 years. By leveraging technology to make financial services and commerce more convenient, affordable, and secure, the PayPal platform is empowering more than 375 million consumers and merchants in more than 200 markets to join and thrive in the global economy.

Investment focus

Financial Services, FinTech, Marketplace
Seed, Grant, Funding Round
United States, Ireland, Sweden

Portfolio highlights

Fordefi — The MPC wallet platform and Web3 gateway from Fordefi allow institutions to connect to dApps across multiple chains while keeping digital assets secure. Fordefi is the first institutional MPC wallet and security platform designed for decentralised finance. It provides MPC key management, self-service DeFi policy controls, time-of-transaction smartcontract insights, transaction simulation, and risk alerts.
CoPilot — CoPilot is pioneering Assisted Commerce for big-ticket purchases – starting with cars. You are the one spending the money - shouldn't you have an expert on your side? We founded CoPilot to make that a reality. For the average car buyer, who is not a car expert or enthusiast, car shopping can be a time consuming, frustrating process that leavespeople feeling alone and disadvantaged. CoPilot is changing this dynamic. Like a trusted friend who is knowledgeable about cars, knows where to look and what to buy, CoPilot provides car shoppers with an expert partner who empowers them to discover the perfect car at the best possible price with ease and confidence.
Lava Network — Lava Network aims to be a marketplace for blockchain data.

Foreign & Commonwealth Office is a government organization that provides tourists and travellers with travel alerts, tips, and advice. It promotes the United Kingdom's interests overseas supporting its citizens and businesses around the globe.Foreign & Commonwealth Office has a worldwide network of embassies and consulates thatemploys over 14,000 people in nearly 270 diplomatic offices. It works with international organizations to promote British interests and global security, including the EU, NATO, Foreign & Commonwealth Office was founded on January 1, 1936 and is based in London, United Kingdom.

Investment focus

Medical, Logistics, E-Commerce
Seed, Pre-Seed
Kenya, Mauritius, South Africa

Portfolio highlights

Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
AgroCenta — AgroCenta is an online platform that connects the smallholder farmer in the staple food (rice, maize, millet and soybean) value chain to a wider online market to trade
HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford

Goodwater empowers exceptional entrepreneurs everywhere to change the world for the better. They believe consumer technology is a force on earth, shaping culture and transforming the global economy at unprecedented speed and scale. They invest in promising entrepreneurs to solve pressing problems. As a combined force, Goodwater companies are aglobal force for change, poised to measurably improve billions of lives.

Investment focus

FinTech, Financial Services, E-Commerce
Seed, Series A, Series B
United States, India, South Korea

Portfolio highlights

Vendah — Social commerce platform democratizing the e-commerce in LATAM through local entrepreneurs
Zepto — India's fastest grocery delivery service.
TANGGapp — Send money to the Philippines with the best exchange rates! Money transfers are received in minutes. Get full transparency on your transaction - no FX markups or secret costs. Download TANGapp today and get started!

We are an early-stage Venture Capital Firm investing in outstanding teams with convincing products and high growth potential.

Investment focus

Software, Apps, Health Care
Seed, Funding Round, Series A
Austria, United States, Germany

Portfolio highlights

FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.

Jozi Angels is an angel network based in Johannesburg, South Africa. We exist to grow the startup ecosystem and facilitate the growth of innovative startups.

Investment focus

B2B, Medical, Wellness
Pre-Seed
South Africa

Portfolio highlights

Jobox — Jobox is a student recruitment platform, built to connect employers, students and graduate career offices. Our focus is to improve graduate employability by ensuring all students have the skills they need to enter, stay in, and progress in the world of work.Jobox’s ecosystem provides employers with access to the best diverse & youthfultalent, students with more employment opportunities and universities with data-driven insights aimed at driving graduate employability forward.
Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!
TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.

Operating out of Stellenbosch in South Africa and backed by two family offices Angelhub Ventures's team is passionate about early stage investments in (South) Africa. Being entrepreneurial ourselves, we thoroughly understand the challenges and changes our founders face – which is why we back them in any way we can. Most importantly, we believein building great businesses and we are in it for the long haul.

Investment focus

Software, Information Technology, Education
Seed, Series A
South Africa, Mexico, Colombia

Portfolio highlights

Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
Godochurch — GoDoChurch is a cloud-based church administration software which is designed to assist Christian churches and ministries with managing members, Sunday services, events, communications, and more. The system is made up of a base package, covering messaging, news, ministries, lists, church roles, services, events, and growth paths, with additionalmodules for managing follow-ups, groups, and Kids church.
Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Leading Venture Capital & Builder in Southeast Asia | Experts in E-Commerce, B2B, B2C, Fulfilment Startups | Seed, Series A Funding

Investment focus

E-Commerce, Internet, Software
Seed, Pre-Seed, Series A
Nigeria, Indonesia, Thailand

Portfolio highlights

Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
Trade Lenda — With Trade Lenda, get quick finance in Nigeria without collateral.
Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Venture investor in high-growth Founders and Teams using technology to solve large and meaningful problems across Africa

Investment focus

Financial Services, Finance, E-Commerce
Seed, Funding Round, Series A
Kenya, Nigeria, South Africa

Portfolio highlights

MNZL — MNZL is on a mission to expand access to capital for Egyptians.Every person who owns an asset has accumulated wealth in it. When they want liquidity for their projects and needs, they should be able to tap into it as easily as withdrawing from a bank.With an innovative digital platform and products, we are working on making digital access tocapital a reality, and building the future of asset-backed financing in Africa.
Hub2.Io — Welcome to HUB2, the leading FINTECH startup in interoperability and payment infrastructure in Francophone Africa. We are proud to work with all financial industry players in Africa who need stable and high-performing infrastructure, and contribute to their success.
Affinity — Join over 60,000 who trust the Affinity mobile app to manage your personal banking needs and qualify for an Affinity Instant Loan

WZ Capital is a boutique venture capital firm investing in early-stage tech startups.

Investment focus

Medical, Wellness, Health Care
Pre-Seed
South Africa

Portfolio highlights

Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!

We acquire equity in companies that are positioned for growth and create wealth for our shareholders. Our team of investment specialist and entrepreneurs evaluate business opportunities that provide medium to long term growth.

Investment focus

Medical, Wellness, Health Care
Pre-Seed
South Africa

Portfolio highlights

Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!
Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.

Growth Grid Venture Capital Partners

Investment focus

Medical, Software, E-Commerce
Funding Round
South Africa

Portfolio highlights

RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

ASISA Enterprise Development Fund

Investment focus