Top 35 Medical Startup Investors in South Africa (November 2026)

Portfolio highlights

• Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
• Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• NjiaPay — Payments-as-a-Service platform that will streamline your operations and elevate your online payments across the African continent.
• SwiftVee — SwiftVEE is a livestock trading mobile app. They support live webcast livestock auctions and silent auctions. Their platform facilitates the discovery and viewing of livestock auctions.They provide webcast advertising, online auctions, and online livestock insurance services and data products for financial institutions.
• Tanda — As a Tanda Agent, you can sell Kenya's favorite digital products, and grow your duka while you're at it

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• Click2Sure — We provide cloud-based Insurance SaaS solutions for omnichannel distribution, which can save costs & support data-driven decision making. Contact us today.
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• Okja — Visit Okja for freshly baked pastries, great coffee and smoothies. Baked fresh in-house every day.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
• Reflective Learning — Reflective delivers affordable yet effective Maths and English learning tools to South African classrooms, designed to elevate student achievements

Portfolio highlights

• Contro — See a licensed online doctor in South Africa for treatment, advice and prescriptions delivered to your door. Fast, private, doctor-guided care with Zapmed.
• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• SigmaX — SigmaX is an e-learning platform that help the students to learn visualize math and learn it a fun way via online application.

Portfolio highlights

• BankWise — Liga123 merupakan situs slot jackpot 888 slots paling gacor dan juga platform ini terdata paling banyak dicari hari ini karena memiliki akses yang mudah tanpa harus menggunakan Apk tambahan seperti VPN untuk memainkan game favorit.
• Aeon Cyber Defense — Aeon is a cybersecurity company focused on securing cloud, code, runtime, and AI environments,Aeon platform appears to help organizations identify and manage security risks across modern, cloud-native technology stacks.AeonSec positions itself around integrated security visibility and protection for rapidly evolving software and AI infrastructure
• Talent Nation — Talent Nation trains and places AI engineers with businesses through its Learn2Earn academy.

Portfolio highlights

• Farm to Feed — One third of all food is lost or wasted, enough to feed the number of hungry people twice worldwide. Food loss and waste contributes to 10% of greenhouse gases globally. We aggregate and repurpose imperfect and surplus produce to create a healthier planet.
• Energiesprong — Energiesprong is a revolutionary, whole house refurbishment and new built standard and funding approach.
• Honeycomb Credit — Grow your business and raise up to $250,000 in crowdfunded community capital from your customers, fans, and local friends.

Portfolio highlights

• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
• Ngobese And Associates — Ngobese And Associates is a Financial Services providing firm offering brokeraging, advisory and intermediary services.

Portfolio highlights

• Kaon — Discover prompts and AI apps built by a global community, or publish your own. FlowGPT is an open platform for building and sharing with AI.
• Egoist Machines — Egoist Machines builds efficient full-stack ML infrastructure for reliable AI systems, from model serving and evaluation to secure deployment and operations.
• Wrtn Technologies — Bring AGI Close to People

Portfolio highlights

• Yeah — Yeah is a financial technology company that offers payment processing services while building a credit profile for the banked and unbanked.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
• Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.

Portfolio highlights

• Zazu — Manza is an all-in-one financial platform for African SMEs, helping businesses manage payments, automate cash flow, and access real-time financial insights from one simple dashboard.
• Fincart — Fincart is a leading shipping platform in Egypt, connecting your business with top courier services, automating operations, and helping you scale your eCommerce logistics.
• Udu Technologies — Explore GPU cloud and hardware through AGH Cloud, UduTech's flagship product, and AI advisory for teams in the United States, Africa, the Caribbean and beyond.

Portfolio highlights

• Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
• Trade Lenda — Trade Lenda is digital financial service solution enabling access to credit for MSMEs leveraging alternative data sources to qualify character and capacity in Nigeria.It’s a known fact access to finance is a major challenge for MSMEs with a $5trillion opportunity market across developing economies. According to reports from PWC and IFC, MSMEsaccount for about 84% of the jobs created in this region and about 50% of the GDP of the African economies. However without needed finance, most of them are likely to shut down within first 2-5 years. Today with our smart data algorithm, we leverage on data to evaluate character and capacity of every request thus removing focus on upfront collateral and cutting bottle necks associated to getting credits by MSMEs. We are not stopping there but also going a step further to provide micro savings, insurance, investment and pension soon for MSMEs.
• Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Portfolio highlights

• PsyLabs — Licensed Cultivation and Production Facility - International Supplier of Pharmaceutical Grade Psychoactive Compounds

Portfolio highlights

• Plentify — Plentify connects home appliances with cheaper cleaner energy. It does this with an intelligent residential load management platform which matches demand with clean energy supply for 75% cheaper than batteries. Plentify combines advanced hardware, AI, and user-centric design to create smart home products that delight customers while alsostrengthening electricity systems.
• Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
• Contactable — Contactable operates as a secure identity solutions company. Contactable offers SMEs faster and more cost effective customer on-boarding and validation solutions, whilst giving the customer full control of their personal data.

Portfolio highlights

• Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
• HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
• Keep IT Cool — Raino Tech4Impact is a social enterprise that leveraging technology as an enabler to empower African communities. Founded in 2014, They have been developing technology-driven solutions in health, agriculture, sports, green energy and offer business support services.In partnership with various key players in different sectors, they have developedunique and efficient different use cases of technological solutions impacting millions of lives.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• SNAPnSAVE — SNAPnSAVE is a shopping app that gives you cash back when you shop in-store. No paper coupons, no plastic cards and no loyalty points. Just real cash back on items that you buy everyday, leaving you with more to spend on the things you want. Ka ching!
• Pulse — An easy way to share your GoPro videos with friends and your community. Pulse is a social network for sports that connects creators to fans and communities. Trail running, snowboarding, mtb, paragliding, kite surfing

Portfolio highlights

• Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.

Portfolio highlights

• Jahazii — Jahazii helps employers offer on-demand access to earned wages, giving employees financial flexibility without loans while reducing pressure on HR and payroll teams. Funds on M-PESA in seconds, at no cost to you.
• TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
• The Awareness Company — We use data to tell stories that are useful to humans.

Portfolio highlights

• Strove — Healthier people. Stronger businesses. Your employees are your greatest asset. Taking care of their physical and mental health has never been more important.
• EnviSync — EnviSync is a Large Language Model Operations (LLMops) platform specifically designed to empower global enterprises, particularly in regulated sectors such as finance, healthcare, and legal tech. The platform facilitates the deployment, monitoring, and optimization of LLM applications with high precision. Developed by experts from technology andinstitutional finance, EnviSync addresses critical challenges, including regulatory compliance with standards like GDPR and MiFID II, performance drift detection, and managing inference costs that can impact operational efficiency.
• InfiniNest — InfiniNest is an innovative Adaptive Learning Companion designed to revolutionize education for special children. Leveraging advanced Large Language Models and deep learning, InfiniNest tailors learning materials to each child's unique needs, from dyslexia to autism spectrum disorder. It offers interactive, multimodal content and real-timefeedback, making learning accessible and engaging. InfiniNest also integrates assistive technologies and provides continuous assessment, helping educators and parents track progress and identify areas for support. By fostering collaborative learning and emotional well-being, InfiniNest ensures every child has the tools to succeed and thrive in their educational journey.

Portfolio highlights

• Lupiya — Lupiya is a financial technology company that provides digital lending services designed to help individuals and small businesses access short-term credit and installment financing. The platform offers mobile-accessible loans that can be used for expenses such as personal needs, business cash flow, or emergency payments, using an online applicationprocess that evaluates creditworthiness through alternative data and behavioral indicators. Lupiya’s services include flexible repayment schedules, automated disbursement, and electronic account management so users can monitor balances and repayment activity within the app or web interface. The company also offers tools for budgeting and payment reminders to support borrowers in managing their credit obligations. Through integrations with local payment networks and banking partners, Lupiya facilitates secure fund transfers and compliance with financial regulations. Its lending infrastructure is tailored to expand access to credit for underserved populations and small enterprises that may have limited access to traditional banking services.
• Seamfix — Seamfix helps governments, regulators and enterprises redesign, digitise and operate trust-critical processes with consulting, proven technology and global delivery.
• Alma Clinics — ALMA CLINICS Primary Healthcare with Advanced Blockchain, AI technology. BEST Clinic providing affordable healthcare, Soweto, Johannesburg, South Africa.

Portfolio highlights

• CubeSpace — Industry-leading modular attitude determination and control (ADCS) products and solutions. Laser-focused on our customers' success. Your global ADCS partner.
• Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• RICE — RCIE is a co-working ecosystem that connects entrepreneurs to a customized curriculum, corporate partners, and access to capital. It is designed to connect the next generation of multi-cultural and women entrepreneurs to the tools and relationships required to turn dreams into reality.The company was founded in 2016 and is headquartered inAtlanta, Georgia.
• PopID — PopID offers a facial recognition platform that enables users to authenticate identity and process payments through biometric verification. Its core service, PopPay, allows customers to link their facial image to a payment method, facilitating transactions at participating businesses without the need for physical cards or mobile devices. The systemsupports various retail formats, including kiosks, drive-thrus, and counter services, and integrates with loyalty programs to personalize the customer experience. PopID's technology has been adopted by merchants such as Whataburger and Steak 'n Shake, aiming to streamline ordering and checkout processes. The company emphasizes user consent and data security, storing encrypted biometric data and allowing users to opt-in or out at their discretion. PopID has also expanded internationally, partnering with entities like SoftBank's Japan Computer Vision to introduce its services in markets such as Japan.
• Shopware — Shopware is a trendsetting ecommerce platform to power your online business. Our ecommerce solution offers the perfect combination of beauty & brains you need to build and customize a fully responsive online store.

Portfolio highlights

• BIMA — BIMA is an insurtech player using mobile technology to provide insurance and health services to emerging markets. To serve its customers, the company has developed a proprietary technology platform, established exclusive partnerships with mobile operators, and built relationships with international insurers. BIMA utilizes its technology platform toserve customers in 13 countries across Asia, Africa, and Latin America and has reached to date 31 million subscribers.
• CrowdForce — CrowdForce is an offline distribution network for market research and financial services. The company empowers businesses to drive mass adoption of digital, crypto, and financial services through the use of mobile technology to help businesses, banks, digital wallets, multinational organizations, NGOs, and government agencies to reach theunderserved population in their communities.CrowdForce was founded in 2016 and is headquartered in San Francisco, California.
• Helium Health — Helium Health empowers healthcare providers in Africa with digital tools, financing solutions, and data partnerships. Learn more about our innovative solutions.

Portfolio highlights

• Motai —
• Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
• Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Portfolio highlights

• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
• Cape Doctors — Find a doctor near you at CA Cape Doctors in Rondebosch and Claremont. Medical aid accepted. Call or book your GP appointment online.
• NewForm Foods — NewForm Foods aims to reinvent food systems for planet, health, and animal welfare. The company offers innovative technology for food producers to create sustainable, animal-friendly products.

Portfolio highlights

• Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.
• Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
• Ridge — Ridge structures natural assets into regulated financial products, issued with an ISIN and accessible through existing banking infrastructure.

Portfolio highlights

• DOZ — Control any website with natural language. Automate browsing, forms, emails and more.
• EMGuidance — EMG Technologies is a socially minded company. They vision is to 'improve patient-care globally. They aim to do this by providing medical professionals free, instant access to trusted, on-the-ground, local clinical facilitation and medicines information.
• Hi5 Technologies — Unlock culture with ongoing recognition and feedback. Hi5 is a simple app that enables you to recognise and rate your co-workers. Hi5 helps managers get rich insights about team culture on a dashboard. Team members use a fun app to give feedback and recognition to peers.

Portfolio highlights

• Vula Mobile — Globally, there are 39 million blind people. An estimated 80% of all blindness is preventable or curable, which means that there are in excess of 30 million people around the world who have lost their sight unnecessarily.In the majority of cases, blindness can be prevented or cured through simple, effective and inexpensive procedures likecataract operations. So the main cause of blindness isn’t a lack of treatment options, but rather a lack of access to decent healthcare.

Portfolio highlights

• Funnelll — Funnelll is a one-stop-shop to set up conversion tracking and optimize marketing campaigns to drive conversions and sales. No coding needed!97% of ad campaigns that run without conversion tracking fail to return a positive ROI. Yet, over 50% of websites don't have conversion tracking setup and only an estimated 25% use it effectively.Funnelll wants to empower businesses of all sizes to run high performing marketing campaigns that drives sales and can return as much as 10X the ROI of campaigns they are running today. Funnelll's no-code technology allows companies to setup conversion tracking, directly on their website, and use their customer data to optimize their marketing campaigns for driving sales.
• CommonX — We have created a social solution for the COVID-19 pandemic that people can use to insulate their social networks from the worry or risk of spreading COVID-19. Launching public beta by Nov. 13.
• Jovian Technologies — AI SaaS platform for Food & Beverage Competitive Intelligence & Consumer data Analytics

Portfolio highlights

• Dost — Dost is an AI-powered platform for automating accounts payable and financial document processing. The system digitizes incoming invoices, receipts, and purchase orders using document capture and data extraction features. It supports 3-way matching, approval workflows, and integration with existing ERP systems. Dost provides a dedicated supplierportal where partners can upload their documents, track invoice status, and engage directly, improving transparency. From a security perspective, it maintains complete traceability by logging every action in an audit trail and applying role-based access controls and encryption.
• Medipreço — MediPreco is a collaborative platform that uses mobile technology and the community to market medicines holistically.
• Rebill — Rebill.com is the payments and subscriptions platform specifically designed for digital businesses and global companies scaling in Latin America.With our platform and API, companies can integrate over 100 local payment methods from the region, including cards, bank transfers, cash, and even wallets. In addition, they always receive the best humansupport with fair pricing and utmost transparency, enabling them to scale across the region 10 times faster.We are backed and have received investment from some of the world's leading funds such as Tiger Global Management, Soma Capital, SV Angel, Y Combinator, as well as incredible angel investors like Guillermo Rauch (Vercel), Arash Ferdowsi (Dropbox), among others.

Portfolio highlights

• DoorDash — Doordash provides restaurant food delivery services connecting customers with local businesses. The company is passionate about transforming local businesses and dedicated to enabling new ways of working, earning, and living. By building the last-mile delivery infrastructure for local cities Doordash is bringing communities closer. It connectscustomers with their favorite local and national restaurantsAndy Fang, Evan Moore, Stanley Tang, and Tony Xu launched the company as PaloAltoDelivery.com in 2013, which became DoorDash, Inc. in October 2014. It is headquartered in San Francisco, California.
• Re:Build — Re:Build Manufacturing helps organizations move from concept to full-scale production by uniting design, engineering, and manufacturing to bring innovative products to market.
• Phillips Edison & Company — Phillips Edison & Company is one of the largest real estate investment trusts in the shopping and grocery sector. Let us find your perfect space today!

Portfolio highlights

• Drax Group — Our purpose is to enable a zero carbon, lower cost energy future. Our ambition is to become carbon negative by 2030.
• Castelion — We are a modern defense production company building the next generation of military hypersonic, vehicle, and strike systems to deter future wars.
• Albert Invent — 1000’s of scientists, technicians, and engineers across 30+ countries rely on Albert’s end-to-end Cloud Platform to accelerate the innovation of new materials. With Albert, R&D organizations get the data insights and tools needed to increase speed to market, automate regulatory compliance, and heighten the impact of new products.Built fromthe ground up for the chemical and material science industry, the Albert Platform connects R&D processes and creates a single data source of truth across the R&D organization. Augmented with AI, machine learning and a comprehensive materials database, key platform functionality includes inventory, worksheets, workflows, tasks, and more. www.albertinvent.com

Portfolio highlights

• Satlyt — Satlyt helps satellites run AI and applications onboard, process data in orbit and work together as a network.
• Aethex — End to end voice agents localized for your market
• Talent Nation — Talent Nation trains and places AI engineers with businesses through its Learn2Earn academy.

Portfolio highlights

• Voltrac — To Secure Our Borders and Food Supply.
• enspired — Revolutionize battery storage with AI-powered BESS optimization. Our energy trading platform ensures smart, real-time market access. Contact us today!
• Aitiologic — A precision medicine startup providing multi-modal liquid biopsy solutions for early disease detection and targeted therapy.