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Top 15 Medical Startup Investors in South Africa (June 2026)

The most active venture capital funds and angel investors investing in South Africa Medical startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Medical startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Psyence Biomedical
VC Fund
2 South Africa Corporate Round Medical, Health Care, Pharmaceutical $500k–$3.5M
54 Collective
VC Fund
2 Kenya, Nigeria, South Africa Seed, Pre-Seed Health Care, Information Technology, FinTech $40k–$4M
ASISA Enterprise Development Fund
VC Fund
1 South Africa Medical, E-Commerce, Health Care
Growth Grid Venture Capital Partners
VC Fund
1 South Africa Medical, Software, E-Commerce
Ardent Capital
VC Fund
1 Nigeria, Indonesia, Thailand Seed, Pre-Seed, Series A E-Commerce, Internet, Software
Goodwater Capital
VC Fund
1 United States, India, South Korea Seed, Series A, Series B FinTech, Financial Services, E-Commerce
HAVAÍC
VC Fund
1 South Africa, United States, Kenya Seed, Series A Software, Health Care, FinTech $57k–$15M
AngelHub Ventures
VC Fund
1 South Africa, Mexico, Colombia Seed, Series A, Pre-Seed Software, Information Technology, Education $300k–$2.3M
i-Cubed Capital
VC Fund
1 South Africa Pre-Seed Medical, Wellness, Health Care
Enza Capital
VC Fund
1 Kenya, Nigeria, South Africa Seed, Series A Financial Services, Finance, E-Commerce $238k–$31M
WZ Capital
VC Fund
1 South Africa Pre-Seed Medical, Wellness, Health Care
PayPal
VC Fund
1 United States, Ireland, United Kingdom Seed, Grant Financial Services, FinTech, Software $15k–$18M
Foreign & Commonwealth Office - UK
VC Fund
1 Kenya, Mauritius, South Africa Seed, Pre-Seed Medical, Logistics, E-Commerce $500k–$790k
Jozi Angels
VC Fund
1 South Africa, Kenya Pre-Seed, Seed B2B, Finance, Lending $39k–$1M
PUSH Ventures
VC Fund
1 Austria, United States, Germany Seed, Series A Software, Apps, Health Care
Access all 36 investors in South Africa Medical startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Psyence Biomedical
VC Fund · Toronto, Ontario, Canada · 2 investments in South Africa Medical startups

Psyence Biomedical is a life science biotechnology company that focuses on advancement of psychedelic medicines.

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Investment focus

  • Industry: Medical, Health Care, Pharmaceutical
  • Stage:Corporate Round
  • Geography: South Africa

Investor stats

  • Total investments: 2
  • Round size: Corporate Round $500k–$3.5M
  • Lead/follow: 100% lead, 0% follow

Portfolio highlights

  • PsyLabs — PsyLabs focuses on cultivating and producing trippy active pharmaceutical ingredients and isolates for use in research, clinical trials, and medication development.
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54 Collective
VC Fund · Johannesburg, NA - South Africa, South Africa · 2 investments in South Africa Medical startups

Building and scaling African tech startups with catalytic capital, value-add support and our global network.

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Investment focus

  • Industry: Health Care, Information Technology, FinTech
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 107
  • Round size: Seed $40k–$4M; Pre-Seed $40k–$1.3M
  • Lead/follow: 36% lead, 64% follow

Portfolio highlights

  • mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
  • REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
  • Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.
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ASISA Enterprise Development Fund
VC Fund · 1 investments in South Africa Medical startups

ASISA Enterprise Development Fund

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Investment focus

  • Industry: Medical, E-Commerce, Health Care
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
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Growth Grid Venture Capital Partners
VC Fund · 1 investments in South Africa Medical startups

Growth Grid Venture Capital Partners

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Investment focus

  • Industry: Medical, Software, E-Commerce
  • Geography: South Africa

Investor stats

  • Total investments: 3
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.
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Ardent Capital
VC Fund · Bangkok, Krung Thep, Thailand · 1 investments in South Africa Medical startups, 7 in the past 12 months

Leading Venture Capital & Builder in Southeast Asia | Experts in E-Commerce, B2B, B2C, Fulfilment Startups | Seed, Series A Funding

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Investment focus

  • Industry: E-Commerce, Internet, Software
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Nigeria, Indonesia, Thailand

Investor stats

  • Total investments: 37
  • Lead/follow: no public data

Portfolio highlights

  • Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
  • Trade Lenda — With Trade Lenda, get quick finance in Nigeria without collateral.
  • Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.
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Goodwater Capital
VC Fund · Burlingame, California, United States · 1 investments in South Africa Medical startups, 67 in the past 12 months

Goodwater empowers exceptional entrepreneurs everywhere to change the world for the better. They believe consumer technology is a force on earth, shaping culture and transforming the global economy at unprecedented speed and scale. They invest in promising entrepreneurs to solve pressing problems. As a combined force, Goodwater companies are aglobal force for change, poised to measurably improve billions of lives.

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Investment focus

  • Industry: FinTech, Financial Services, E-Commerce
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, South Korea

Investor stats

  • Total investments: 316
  • Lead/follow: no public data

Portfolio highlights

  • Vendah — Social commerce platform democratizing the e-commerce in LATAM through local entrepreneurs
  • Zepto — India's fastest grocery delivery service.
  • TANGGapp — Send money to the Philippines with the best exchange rates! Money transfers are received in minutes. Get full transparency on your transaction - no FX markups or secret costs. Download TANGapp today and get started!
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HAVAÍC
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

HAVAÍC is an investment and advisory firm that specialises in early-stage, high-growth African businesses with proven concepts and global prospects, offering investment opportunities to sophisticated investors and international venture capital companies with an interest in Africa. As a complementary offering, HAVAÍC provides corporate advisory andcapital raising services to emerging, internationally scalable businesses.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Seed, Series A
  • Geography: South Africa, United States, Kenya

Investor stats

  • Total investments: 44
  • Round size: Seed $57k–$4M; Series A $1.9M–$15M
  • Lead/follow: 61% lead, 39% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • AURA — A South African cloud-based security and safety startup .
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AngelHub Ventures
VC Fund · Stellenbosch, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Operating out of Stellenbosch in South Africa and backed by two family offices Angelhub Ventures's team is passionate about early stage investments in (South) Africa. Being entrepreneurial ourselves, we thoroughly understand the challenges and changes our founders face – which is why we back them in any way we can. Most importantly, we believein building great businesses and we are in it for the long haul.

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Investment focus

  • Industry: Software, Information Technology, Education
  • Stage:Seed, Series A, Pre-Seed
  • Geography: South Africa, Mexico, Colombia

Investor stats

  • Total investments: 14
  • Round size: Seed $2M–$2.3M; Series A $300k–$1.7M
  • Lead/follow: 71% lead, 29% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Motai
  • Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
  • Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.
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i-Cubed Capital
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

i-Cubed Capital provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retiremen, including savings plans with tax incentives.i-Cubed provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retirement, including savings plans with tax incentives. We assess fund managerperformances by reviewing fact sheets and provide our clients with a variety of options to meet their investment objectives.

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Investment focus

  • Industry: Medical, Wellness, Health Care
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 2
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
  • Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
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Enza Capital
VC Fund · Nairobi, Nairobi Area, Kenya · 1 investments in South Africa Medical startups

Venture investor in high-growth Founders and Teams using technology to solve large and meaningful problems across Africa

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Investment focus

  • Industry: Financial Services, Finance, E-Commerce
  • Stage:Seed, Series A
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 52
  • Round size: Seed $238k–$8M; Series A $3.6M–$31M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Tugende — Tugende helps motorcycle taxi drivers own their own motorcycles in eighteen months or less instead of renting indefinitely. Ownership significantly increases income, job security and road safety.
  • Jumba — Jumba is the trusted digital partner for hardware stores. Through tech, we support hardware stores to grow. Get cement at unbeatable prices. Access cement LPOs even at midnight. Get inventory on credit through Jengwa.
  • Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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WZ Capital
VC Fund · 1 investments in South Africa Medical startups

WZ Capital is a boutique venture capital firm investing in early-stage tech startups.

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Investment focus

  • Industry: Medical, Wellness, Health Care
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
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PayPal
VC Fund · San Jose, California, United States · 1 investments in South Africa Medical startups

PayPal has remained at the forefront of the digital payment revolution for more than 20 years. By leveraging technology to make financial services and commerce more convenient, affordable, and secure, the PayPal platform is empowering more than 375 million consumers and merchants in more than 200 market to join and thrive in the global economy.

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Investment focus

  • Industry: Financial Services, FinTech, Software
  • Stage:Seed, Grant
  • Geography: United States, Ireland, United Kingdom

Investor stats

  • Total investments: 35
  • Round size: Seed $45k–$18M; Grant $15k–$110k
  • Lead/follow: 34% lead, 66% follow

Portfolio highlights

  • PopID — PopID is a software company that provides solutions for verifying an individual’s identity based on their face for applications such as loyalty, payment, and entry.
  • Padiepal — Discover the Future of Digital Finance with Padiepal Transforming Digital Finance At Padiepal, we're on a mission to redefine the future of digital finance. With an ever-growing range of innovative services, we cater to the needs of individuals, businesses, and global merchants alike. Our objective is to provide seamless transactions andfinancial solutions that meet the demands of today's fast-paced digital world.Comprehensive Services for Everyone Our offerings are designed to empower users to manage their finances effectively. From dollar virtual accounts to international money transfers, we have services that enhance the user experience. Individuals can enjoy straightforward payment solutions, while businesses can utilize our robust tools to expand their operations globally. By combining technology with financial expertise, Padiepal facilitates smart financial decisions for everyone.Why Choose Padiepal? With a commitment to security and transparency, Padiepal is a trustworthy partner in your financial journey. Our user-friendly interface simplifies engaging with digital finance, making it accessible to all. Moreover, we continuously innovate and adapt our services to remain at the forefront of digital finance trends. Whether you’re a seasoned merchant or just starting your financial journey, Padiepal stands ready to support your goals.
  • Shopware — Shopware is a trendsetting ecommerce platform to power your online business. Our ecommerce solution offers the perfect combination of beauty & brains you need to build and customize a fully responsive online store.
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Foreign & Commonwealth Office - UK
VC Fund · London, England, United Kingdom · 1 investments in South Africa Medical startups

Foreign & Commonwealth Office is a government organization that provides tourists and travellers with travel alerts, tips, and advice. It promotes the United Kingdom's interests overseas supporting its citizens and businesses around the globe.Foreign & Commonwealth Office has a worldwide network of embassies and consulates thatemploys over 14,000 people in nearly 270 diplomatic offices. It works with international organizations to promote British interests and global security, including the EU, NATO, Foreign & Commonwealth Office was founded on January 1, 1936 and is based in London, United Kingdom.

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Investment focus

  • Industry: Medical, Logistics, E-Commerce
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Mauritius, South Africa

Investor stats

  • Total investments: 4
  • Round size: Seed $500k–$790k
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
  • HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
  • Raino Tech4Impact — Raino Tech4Impact is a social enterprise that leverages technology as an enabler to empower African communities. We have been deploying technology-driven solutions in agriculture and health, powered by renewable energy to achieve sustainability.
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Jozi Angels
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Jozi Angels is an angel network based in Johannesburg, South Africa. We exist to grow the startup ecosystem and facilitate the growth of innovative startups.

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Investment focus

  • Industry: B2B, Finance, Lending
  • Stage:Pre-Seed, Seed
  • Geography: South Africa, Kenya

Investor stats

  • Total investments: 5
  • Round size: Pre-Seed $39k–$1M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Jahazii — Jahazii provides an online platform for workforce management. The company offers tools for storing and organizing employee records in one system. It manages scheduling, attendance tracking, and timesheets for different types of workers. The platform connects attendance and payroll functions to support salary processing. It allows employers toautomate payroll calculations and salary disbursement. The company also provides earned wage access, letting employees receive part of their pay before payday.
  • TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
  • The Awareness Company — We use data to tell stories that are useful to humans.
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PUSH Ventures
VC Fund · Vienna, Wien, Austria · 1 investments in South Africa Medical startups

We are an early-stage Venture Capital Firm investing in outstanding teams with convincing products and high growth potential.

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Investment focus

  • Industry: Software, Apps, Health Care
  • Stage:Seed, Series A
  • Geography: Austria, United States, Germany

Investor stats

  • Total investments: 23
  • Lead/follow: no public data

Portfolio highlights

  • FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
  • Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
  • Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.
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Medical Investor funding in South Africa at a glance

Stats across 28 deals from 36 investors.

36
investors
in South Africa Medical startups
28
deals
in South Africa Medical startups
$256k
median round
in South Africa Medical startups
42%
lead investors
lead at least one round
18%
Seed
most common funding stage
97/3
VC / Angel
share of investor count

Access all 36 investors in South Africa Medical startups.

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