Top 15 Medical Startup Investors in South Africa in January 2026

Portfolio highlights

• Billboxx — Empowering SMEs to pay and get paid on time, every time.
• mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.

Portfolio highlights

• NjiaPay — Payments-as-a-Service platform that will streamline your operations and elevate your online payments across the African continent.
• Talk360 — Talk360 is an easy-to-use calling app that helps people make affordable international calls to any mobile and landline number. They believe that reliable communication and digital services must be affordable and accessible to everyone, regardless of someone's background. Especially people in emerging countries in Africa, who often need theseservices the most, do not always have the necessary banking possibilities. To bridge this distance, Talk360 will launch the world's first single checkout platform for Africa. This platform will combine all locally available payment methods and currencies across Africa, together with over 1.25 million cash points of sales, and will eventually be available to other companies as well. This means that 500 million Africans will be able to purchase digital services they never had access to before.
• Right Now Response — The future of repairs starts soon. Counting down to smarter tracking in 2025! There are perks to working 24/7, 365 days a year... Like launching the future of repairs ahead of schedule!

Portfolio highlights

• FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
• Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
• Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.

Portfolio highlights

• Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
• Godochurch — GoDoChurch is a cloud-based church administration software which is designed to assist Christian churches and ministries with managing members, Sunday services, events, communications, and more. The system is made up of a base package, covering messaging, news, ministries, lists, church roles, services, events, and growth paths, with additionalmodules for managing follow-ups, groups, and Kids church.
• Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Portfolio highlights

• Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• CoreWeave — CoreWeave provides flexible compute services and products to empower innovators. The company provides GPU accelerated compute solutions to the CGI and machine learning industries. Backed by quality hardware and systems management infrastructure, CoreWeave is built to help clients scale and adapt to evolving compute requirements at industry leadingeconomics.
• 10X Banking — Put the world's most powerful and comprehensive cloud native banking platform at the core of your bank.
• InCorp Chain — Bridging Corporates Adoption Towards Crypto Through $ICNX

Portfolio highlights

• Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
• CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
• RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.

Portfolio highlights

• Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.

Portfolio highlights

• Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
• Trade Lenda — With Trade Lenda, get quick finance in Nigeria without collateral.
• Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Portfolio highlights

• Vendah — Social commerce platform democratizing the e-commerce in LATAM through local entrepreneurs
• Zepto — India's fastest grocery delivery service.
• TANGGapp — Send money to the Philippines with the best exchange rates! Money transfers are received in minutes. Get full transparency on your transaction - no FX markups or secret costs. Download TANGapp today and get started!

Portfolio highlights

• Jobox — Jobox is a student recruitment platform, built to connect employers, students and graduate career offices. Our focus is to improve graduate employability by ensuring all students have the skills they need to enter, stay in, and progress in the world of work.Jobox’s ecosystem provides employers with access to the best diverse & youthfultalent, students with more employment opportunities and universities with data-driven insights aimed at driving graduate employability forward.
• Contro — Get your health and confidence products prescribed online and delivered to your door for free without the waiting rooms!
• TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.

Portfolio highlights

• Fordefi — The MPC wallet platform and Web3 gateway from Fordefi allow institutions to connect to dApps across multiple chains while keeping digital assets secure. Fordefi is the first institutional MPC wallet and security platform designed for decentralised finance. It provides MPC key management, self-service DeFi policy controls, time-of-transaction smartcontract insights, transaction simulation, and risk alerts.
• CoPilot — CoPilot is pioneering Assisted Commerce for big-ticket purchases – starting with cars. You are the one spending the money - shouldn't you have an expert on your side? We founded CoPilot to make that a reality. For the average car buyer, who is not a car expert or enthusiast, car shopping can be a time consuming, frustrating process that leavespeople feeling alone and disadvantaged. CoPilot is changing this dynamic. Like a trusted friend who is knowledgeable about cars, knows where to look and what to buy, CoPilot provides car shoppers with an expert partner who empowers them to discover the perfect car at the best possible price with ease and confidence.
• Lava Network — Lava Network aims to be a marketplace for blockchain data.

Portfolio highlights

• MNZL — MNZL is on a mission to expand access to capital for Egyptians.Every person who owns an asset has accumulated wealth in it. When they want liquidity for their projects and needs, they should be able to tap into it as easily as withdrawing from a bank.With an innovative digital platform and products, we are working on making digital access tocapital a reality, and building the future of asset-backed financing in Africa.
• Hub2.Io — Welcome to HUB2, the leading FINTECH startup in interoperability and payment infrastructure in Francophone Africa. We are proud to work with all financial industry players in Africa who need stable and high-performing infrastructure, and contribute to their success.
• Affinity — Join over 100,000 who trust the Affinity mobile app to manage their banking needs, from savings to payments, as well as instant loans