Top 50 Startup Investors in Puerto Rico (June 2026)

Portfolio highlights

• Inaam — impact investing made simple. pick your values, build a real portfolio, track where your money goes. $10/month. ASIC-regulated. built for 18-30s.
• PayToMe.co — PayToMe.co offers innovative and secure payment solutions including text-to-pay, digital invoicing, and digital checkbook services.
• Kybele's Garden — Kybele's Garden focus on algae-based bioponics and algae fermentation methods. Their differentiation strategy boosts harvest yield, source efficiency, and functional content, while improving sensory attributes and shelf life. These technologies can be used in agrifood and skin care, and integrated into existing producers' systems.

Portfolio highlights

• Akave Cloud — Akave is a decentralized data management network that supports the next generation of data-driven apps and marketplaces.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.
• Silhouette Exchange — Silhouette is a privacy-focused decentralized trading protocol integrated with the Hyperliquid ecosystem.

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Kiwi — Kiwi is a fintech dedicated to helping Latinos build credit history and improve financial literacy.
• BackChannel — BackChannel is an online B2B platform for inventory transactions and for buying and selling online goods.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.

Portfolio highlights

• KINO — KINO is a film production company that brings fans behind the scenes of their favorite hollywood films.
• Tanssi Network — The Tanssi Network is a permissionless appchain infrastructure protocol designed for swift and effortless deployment of application-specific blockchains.
• Virtualtech Frontier — Virtualtech Frontier develops business processes through virtual reality technology. It operates virtual event platforms, metaverse services, and virtual reality solutions. Virtualtech Frontier was founded in 2021 and is based in Selangor, Malaysia.

Portfolio highlights

• SOLX — SOLX is a manufacturing company that develops and retails solar panels.

Portfolio highlights

• Ballet — Ballet Crypto is a companion mobile app, which enables sending of cryptocurrency, checking market value and activating additional currencies. The use of the mobile app is completely optional, as you do not need it to receive and store your cryptocurrency safely.
• Fog Works, Inc. — W3 Storage Lab has assembled a world-class team with a unique combination of P2P networking, blockchain, and entrepreneurial experience.
• Enzymecode Biotechnology — Enzymecode Biotechnology is a biotech company that specializes in the development and production of brain health and other nutritional raw materials and food ingredients.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
• Doppler Finance — Doppler Finance is a yield-earning platform that unlock earning opportunities within the XRPL ecosystem

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Portfolio highlights

• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• Mesh —
• MYX — MYX is a decentralized derivative exchange that "uses intelligent rates and exposure hedging mechanisms to ensure protocol stability and provide sustainable high returns" through a peer-to-pool-to-peer paradigm.
• Civil — A starter blog demonstrating what Gatsby can do.

Portfolio highlights

• Kiwi — Kiwi is a fintech dedicated to helping Latinos build credit history and improve financial literacy.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.

Portfolio highlights

• Key Media — Key Media is an events and niche publishing company.
• Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
• Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Portfolio highlights

• Bitwage — Payroll, invoicing & benefits for digital assets. Bitwage offers services for companies and direct to workers. Workers can sign up and get direct deposit accounts to get paid from any company or client. Workers locally receive unique digital asset benefits. Workers internationally get paid faster & cheaper than traditional wires.
• FV Bank — FV Bank is a US licensed bank and a digital asset custodian that provides banking, payments, digital asset custody, and Visa cards to the U.S. and international customers.
• Hexa Wallet — Own HexaWallet.io today. Secure checkout and guided transfer support. No hidden fees.

Portfolio highlights

• Jefa — Jefa is a digital financial platform for women. Starting in Mexico, Jefa provides a digital app with access to a financial marketplace in an affordable, convenient, and secure solution.Jefa's goal is to empower women to live without limits or obstacles. Jefa does this by giving its clients access to fair, affordable, and secure financialservices through a mobile account.
• Moonflow — Mejora tus procesos de cobranzas y ahorra hasta un 75%. Software de Gestion de Cobranzas para Empresas,
• Flourish Fi — Creating a banking experience that people love. Enable banks and credit unions to strengthen relationships with a rewards system, financial literacy and savings journey.

Portfolio highlights

• Rails — Experience unparalleled speed and efficiency with Rails, your go-to platform for lightning-fast crypto perpetuals trading.
• PocketHealth — Get early access to your medical imaging results. Trusted by more than 2M patients and 900 hospitals and clinics.
• CWX — CWX is a full-service enterprise cloud consulting company.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• ALKEMIO — ALKEMIO is a developer of a bio-magnetic technology intended to transform electronic waste into quality battery-grade metals.
• Integriculture — Integriculture makes cellular agriculture products to improve sustainability, food security, and reduce public health problems. The company offers a developed patented general-purpose large-scale cell culture system that can culture wide range of cells without external addition of expensive growth factors and provide consumers with affordable cleanmeat.Founded in 2015, Integriculture is headquartered in Tokyo, Japan.
• HEARTio — Heart I/O is a digital diagnostic startup helping emergency providers identify heart abnormalities in Pittsburgh, PA.

Portfolio highlights

• Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
• Streem — Easy AR-powered remote video support & communication platform with AI data capture to get the job done from anywhere. Streem is better than being there.
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• 3RM — Verified contact at any decentralized organization. Manage new business, partnerships, and engagement across organizations like never before.
• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Faith Tribe — Faith Tribe is a open- source fashion design platform that focuses on NFT minting, P2P transactions.

Portfolio highlights

• Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

Portfolio highlights

• Vend Park — Unlock the true value of your parking asset with a fully digital parking access and revenue control system
• Wolf — Get all the tools and expertise you need to launch your own branded on-demand staffing platform, SpaaS and apps.
• Dataplor — Leveraging machine learning, AI, and human capital, dataplor delivers verified international places data to the world's leading companies.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.
• ClassCalc — Students can use their smartphones instead of using or buying a TI calculator, and teachers can ensure they only use the ClassCalc calculator app in class. We believe students and teachers should have a choice other than the same expensive, difficult to learn and use dedicated-purpose TI calculator they have been forced to use for decades.ClassCalc provides a multi-subject math calculator with scientific, graphing, and matrix functionality in an easy-to-use smartphone app. Teachers are able to lock down the student’s phone to only the ClassCalc app for class time, quizzes, tests… no cheating or outside distractions (social media, texting etc).
• Turno, formerly TurnoverBnB — Find now a local Airbnb cleaning service; automatically schedule your existing cleaners. Integrated with all reservations platforms and channel managers.

Portfolio highlights

• Transak — Transak offers a simple integration to allow your users to buy more than 100+ cryptocurrencies with credit/debit cards, or bank transfers in more than 120+ countries.
• Agents World — Agents World operates as an web3 AI firm.
• Ooga Booga — Multichain Liquidity Aggregator

Portfolio highlights

• CELL Studio — A blockchain software development company with a dedicated focus on the BTC ecosystem, committed to advancing the Nervos BTCKB initiative
• Avalon Finance — Institutional Bitcoin-backed lending, borrowing, earning, and liquidity. Fully on-chain and regulatory-compliant.
• Stoneblade Entertainment — Stoneblade Entertainment operates as a publisher of strategy games.

Portfolio highlights

• CB International Bank — CBiBank is a U.S. commercial bank with a U.S. banking license,Committed to providing one-stop global financial solutions for export companies, import companies, cross-border e-commerce, overseas companies and individual investor users, including overseas bank account opening, cross-border remittance, cross-border payment, global trade collection, etc., Offshore bank account opening is efficient and fast, international remittances are safe, and bilingual and cross-time zone online services are supported.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Optic — Optic monitors blockchains to reveal the origins of any NFT and how it’s been reimagined, remixed, or copied.

Portfolio highlights

• Nammu21 — Nammu21 is the developer of a digitization and analytics platform which deconstructs, digitizes, and analyzes complex interconnected transaction documents across the finance ecosystem enabling stakeholders to access, extract and use data to generate new value.
• Zion — Join our mission in creating the last platform you will ever build
• Formidium — Sudrania.com offers Fund Administration, Fund Accounting, Investor Services, Taxation Services, Regulatory Filings and Financial Statements

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• GALY — GALY biocrafts premium cocoa and cotton with quality, traceability, and scalable supply for modern brands.
• Buupass — BuuPass is Kenya's market leader for online bus booking. We enable travelers to reserve seats and make payments in a convenient and timely way. Try BuuPass today!
• Vivoo — Get personalized wellness insights with Vivoo's innovative, science-backed products. Understand your body's needs and take control of your body. Shop now!

Portfolio highlights

• Solfium — Solfium is a one-of-a-kind solar energy company dedicated to providing the best solutions for your house, business, or industry. Everything we do is driven by the desire to provide you with the greatest possible experience.
• Genius Foods — Genius Foods is a foodtech focused on extending the shelf life of food products.
• Crabi — Full stack, digital car insurance

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Aleo — Welcome to Aleo. The first platform for fully private applications. Write, run, and host private applications on Aleo. The ultimate toolkit for building private applications is finally here.
• Badger DAO — A community of builders bringing Bitcoin to DeFi

Portfolio highlights

• OpenAssets — OpenAssets builds open infrastructure and technology for digital financial systems and tokenized capital markets. The company develops standards and platforms for issuing and managing tokenized assets, digital currencies, and programmable money across major blockchains. Its solutions include tokenization-as-a-service, compliant asset issuancetools, and programmable ownership features for bonds, equities, commodities, and other assets. OpenAssets serves governments, central banks, financial institutions, and digital asset companies seeking to modernize capital markets. The organization also convenes industry alliances to define technical, policy, and governance frameworks for programmable finance.
• Superscrypt — Superscrypt is a blockchain investment firm.
• SpaceComputer — SpaceComputer uses satellites to create a secure blockchain system that resists cyberattacks and physical tampering.

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — DigiBuild develops a construction management software that utilizes blockchain technology. It captures transactions from all of the different systems being utilized on the project and puts them into a filterable, searchable, and comparable project timeline to remove the waste and fraud for better data insights and decision making that will stopbudget overages.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• MQube — MQube: Next-generation lending platform offering fast, automated mortgage solutions with real-time decisioning and built-in compliance.
• Think Bioscience — Think Bioscience is reimagining synthetic biology by guiding the design and assembly of better medicines through the use of living systems.
• Bluezone Insurance — Bluezone Insurance is an insurtech reinventing life insurance for people with chronic illnesses .

Portfolio highlights

• Convelio — Convelio is a global logistics startup specialized in bulky, fragile and high-value items.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.
• Epoch Biodesign — Mellizyme Biotechnology is currently operating in stealth.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients

Portfolio highlights

• Due — Discover our global payment platform. Powered by open, decentralised and interoperable networks.
• Freename — Redefining Web3 Naming System. Web3 Registrar: custom TLDs and Domains
• BIO Protocol — The BIO Protocol (BIO) allows onchain scientific communities to fund, build, and co-own research and products in specific biomedical domains including lifespan, brain health, and rare disorders. BIO, founded by senior VitaDAO members, empowers worldwide communities of scientists, patients, and investors to take science into their own hands andbring solutions to life more effectively than traditional pharmaceutical companies.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Exabits AI — Exabits' network of GPUs ranges from consumer-grade to H100s, offering the most cost-effective compute because we are obsessed with innovating performance.

Portfolio highlights

• Rhuna — Rhuna is an AI and blockchain platform that transforms event management with NFT ticketing and token rewards.
• Lympid — We believe that anyone should have access to the amazing opportunities found on the blockchain, from DeFi protocols (aave, compound, yearn…) to Crypto Indexes, there's so much to discover! At Lympid you will be able to do it all easily in the same app, and directly through EUR.
• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.
• Solve Therapeutics — Solve Therapeutics is a biopharmaceutical company that develops Antibody Drug Conjugate and Bispecific Therapeutics. The company was founded in 2021 and is headquartered in Belmont, California.

Portfolio highlights

• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Mytra — Supercharged Industrial Productivity with Bots, Software, and Cells
• Tokemak — Automated DeFi Yield Farming & Liquidity Management
• Hubble Network — Connect a Bluetooth device to a global satellite network, delivering affordable, low-power tracking and monitoring for diverse industrial and commercial applications.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• CARV — CARV enables AI Beings to live, evolve, and govern as sovereign intelligences on-chain; not as tools, but as beings that act, learn, and lead.
• Nest Wallet — A Wallet Built for Traders

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Portfolio highlights

• Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
• Rover — Rover is a liquid staking protocol on Botanix that exchanges Bitcoin for rovBTC.
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.