Top 50 Startup Investors in Puerto Rico (June 2026)

Portfolio highlights

• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Valpas — Valpas is the hygiene protocol that reassures your future guests and keeps your hotel clean from the most uncontrollable: bed bugs
• Kiwi — Kiwi is a fintech dedicated to helping Latinos build credit history and improve financial literacy.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.

Portfolio highlights

• Coverio — Coverio is a software company that offers enterprise-wide payroll and hiring management software for web4 companies.
• Metaschool — Join 140K+ developers on Metaschool building in AI & Web3. Explore the official courses of 15+ blockchains or learn to build AI apps using free AI templates.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.

Portfolio highlights

• Ballet — Ballet Crypto is a companion mobile app, which enables sending of cryptocurrency, checking market value and activating additional currencies. The use of the mobile app is completely optional, as you do not need it to receive and store your cryptocurrency safely.
• Fog Works, Inc. — W3 Storage Lab has assembled a world-class team with a unique combination of P2P networking, blockchain, and entrepreneurial experience.
• Enzymecode Biotechnology — Enzymecode Biotechnology is a biotech company that specializes in the development and production of brain health and other nutritional raw materials and food ingredients.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Portfolio highlights

• Ajé — Secure digital transactions and cross-border trade powered by blockchain technology.
• PayToMe.co — PayToMe.co offers innovative and secure payment solutions including text-to-pay, digital invoicing, and digital checkbook services.
• Kybele's Garden — Kybele's Garden focus on algae-based bioponics and algae fermentation methods. Their differentiation strategy boosts harvest yield, source efficiency, and functional content, while improving sensory attributes and shelf life. These technologies can be used in agrifood and skin care, and integrated into existing producers' systems.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
• Doppler Finance — Doppler Finance is a yield-earning platform that unlock earning opportunities within the XRPL ecosystem

Portfolio highlights

• Akave Cloud — Akave is a decentralized data management network that supports the next generation of data-driven apps and marketplaces.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.
• Silhouette Exchange — Silhouette is a privacy-focused decentralized trading protocol integrated with the Hyperliquid ecosystem.

Portfolio highlights

• Transak — Transak offers a simple integration to allow your users to buy more than 100+ cryptocurrencies with credit/debit cards, or bank transfers in more than 120+ countries.
• Agents World — Agents World operates as an web3 AI firm.
• Ooga Booga — Multichain Liquidity Aggregator

Portfolio highlights

• CELL Studio — A blockchain software development company with a dedicated focus on the BTC ecosystem, committed to advancing the Nervos BTCKB initiative
• Avalon Finance — Institutional Bitcoin-backed lending, borrowing, earning, and liquidity. Fully on-chain and regulatory-compliant.
• Stoneblade Entertainment — Stoneblade Entertainment operates as a publisher of strategy games.

Portfolio highlights

• CB International Bank — CBiBank is a U.S. commercial bank with a U.S. banking license,Committed to providing one-stop global financial solutions for export companies, import companies, cross-border e-commerce, overseas companies and individual investor users, including overseas bank account opening, cross-border remittance, cross-border payment, global trade collection, etc., Offshore bank account opening is efficient and fast, international remittances are safe, and bilingual and cross-time zone online services are supported.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Optic — Optic monitors blockchains to reveal the origins of any NFT and how it’s been reimagined, remixed, or copied.

Portfolio highlights

• TACEO — TACEO refers to MPC encrypted compute for Web3.
• Due — Discover our global payment platform. Powered by open, decentralised and interoperable networks.
• Freename — Register Web3 domains, custom TLDs, or import domains. Secure your digital identity today.

Portfolio highlights

• Nammu21 — Nammu21 is the developer of a digitization and analytics platform which deconstructs, digitizes, and analyzes complex interconnected transaction documents across the finance ecosystem enabling stakeholders to access, extract and use data to generate new value.
• Zion — Join our mission in creating the last platform you will ever build
• Formidium — Sudrania.com offers Fund Administration, Fund Accounting, Investor Services, Taxation Services, Regulatory Filings and Financial Statements

Portfolio highlights

• JAN3 — JAN3 provides technologies and solutions for individuals, enterprises, and nation-states to prepare for the future built on Bitcoin.
• Vida — Vida is the AI Agent Operating System for enterprises. Build, deploy, and manage AI agents that call, text, email, and chat at scale with no-code tools.
• OrdinalsBot — We make it easy to inscribe ordinals. Like, really easy.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Mesh —
• MYX — MYX is a decentralized derivative exchange that "uses intelligent rates and exposure hedging mechanisms to ensure protocol stability and provide sustainable high returns" through a peer-to-pool-to-peer paradigm.
• Civil — A starter blog demonstrating what Gatsby can do.

Portfolio highlights

• Kiwi — Kiwi is a fintech dedicated to helping Latinos build credit history and improve financial literacy.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.

Portfolio highlights

• Key Media — Key Media is an events and niche publishing company.
• Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
• Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Portfolio highlights

• Bitwage — Payroll, invoicing & benefits for digital assets. Bitwage offers services for companies and direct to workers. Workers can sign up and get direct deposit accounts to get paid from any company or client. Workers locally receive unique digital asset benefits. Workers internationally get paid faster & cheaper than traditional wires.
• FV Bank — FV Bank is a US licensed bank and a digital asset custodian that provides banking, payments, digital asset custody, and Visa cards to the U.S. and international customers.
• Hexa Wallet — Own HexaWallet.io today. Secure checkout and guided transfer support. No hidden fees.

Portfolio highlights

• Jefa — Jefa is a digital financial platform for women. Starting in Mexico, Jefa provides a digital app with access to a financial marketplace in an affordable, convenient, and secure solution.Jefa's goal is to empower women to live without limits or obstacles. Jefa does this by giving its clients access to fair, affordable, and secure financialservices through a mobile account.
• Moonflow — Mejora tus procesos de cobranzas y ahorra hasta un 75%. Software de Gestion de Cobranzas para Empresas,
• Flourish Fi — Creating a banking experience that people love. Enable banks and credit unions to strengthen relationships with a rewards system, financial literacy and savings journey.

Portfolio highlights

• Rails — Experience unparalleled speed and efficiency with Rails, your go-to platform for lightning-fast crypto perpetuals trading.
• PocketHealth — Get early access to your medical imaging results. Trusted by more than 2M patients and 900 hospitals and clinics.
• CWX — CWX is a full-service enterprise cloud consulting company.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• GALY — GALY biocrafts premium cocoa and cotton with quality, traceability, and scalable supply for modern brands.
• Buupass — BuuPass is Kenya's market leader for online bus booking. We enable travelers to reserve seats and make payments in a convenient and timely way. Try BuuPass today!
• Vivoo — Get personalized wellness insights with Vivoo's innovative, science-backed products. Understand your body's needs and take control of your body. Shop now!

Portfolio highlights

• Solfium — Solfium is a one-of-a-kind solar energy company dedicated to providing the best solutions for your house, business, or industry. Everything we do is driven by the desire to provide you with the greatest possible experience.
• Genius Foods — Genius Foods is a foodtech focused on extending the shelf life of food products.
• Crabi — Full stack, digital car insurance

Portfolio highlights

• ALKEMIO — ALKEMIO is a developer of a bio-magnetic technology intended to transform electronic waste into quality battery-grade metals.
• Integriculture — Integriculture makes cellular agriculture products to improve sustainability, food security, and reduce public health problems. The company offers a developed patented general-purpose large-scale cell culture system that can culture wide range of cells without external addition of expensive growth factors and provide consumers with affordable cleanmeat.Founded in 2015, Integriculture is headquartered in Tokyo, Japan.
• HEARTio — Heart I/O is a digital diagnostic startup helping emergency providers identify heart abnormalities in Pittsburgh, PA.

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Aleo — Welcome to Aleo. The first platform for fully private applications. Write, run, and host private applications on Aleo. The ultimate toolkit for building private applications is finally here.
• Badger DAO — A community of builders bringing Bitcoin to DeFi

Portfolio highlights

• CAP Labs — CAP Labs is a stablecoin developer platform that produces various denominations of redeemable stablecoins.
• DoubleZero — DoubleZero is developing a global fiber network intended for high-performance distributed systems and blockchains. It seeks to enhance blockchain performance by establishing a dedicated physical infrastructure layer for communication.
• Pointsville — Empowering businesses to efficiently create, manage and service digital assets and loyalty programs, driving innovation and inclusion.

Portfolio highlights

• Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
• Streem — Easy AR-powered remote video support & communication platform with AI data capture to get the job done from anywhere. Streem is better than being there.
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Faith Tribe — Faith Tribe is a open- source fashion design platform that focuses on NFT minting, P2P transactions.
• Mythic Protocol — The Central Hub for Mythic Operatives to conduct their operations

Portfolio highlights

• RobinFood — RobinFood is the leader in cloud-restaurants in Latin America with presence in Colombia, Brazil and Mexico. RobinFood was founded in 2018
• PRoduce — PRoduce! is a multi-platform marketplace for local produce. It aims to connect local producers with buyers, including chefs, restaurants, hotels, and direct customers, to decrease the Island’s imported goods. It was founded in 2018 and is based in San Juan, Puerto Rico.
• Afia — Afia Falafel and Kibbeh are made from our family recipes and are prepared in the traditional way, with only simple ingredients, and no preservatives. Available frozen, Afia products fit a range of dietary needs, including gluten-free, halal, vegetarian and vegan options.

Portfolio highlights

• Biconomy — Blockchain transactions made simple. Enable Gasless meta-transactions, instant cross-chain transfers, easy layer 2 onboarding & zero failed transactions
• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
• Charquiqui — Charquiqui specializes in manufacturing red meat products intended to offer cured meat snacks. It offers retail products and packages of red meat that contains beef bites, cured in natural brine, and partially dehydrated on grills.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — DigiBuild develops a construction management software that utilizes blockchain technology. It captures transactions from all of the different systems being utilized on the project and puts them into a filterable, searchable, and comparable project timeline to remove the waste and fraud for better data insights and decision making that will stopbudget overages.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Mytra — Supercharged Industrial Productivity with Bots, Software, and Cells
• Tokemak — Automated DeFi Yield Farming & Liquidity Management
• Hubble Network — Connect a Bluetooth device to a global satellite network, delivering affordable, low-power tracking and monitoring for diverse industrial and commercial applications.

Portfolio highlights

• Hydrolix — Hydrolix is an early-stage startup with an ambition to change the economics of high density data. The company develops a query service technology intended to process petabyte-scale time series data.Hydrolix's cloud-based query service utilizes proprietary compression and indexing technology, allowing customers to process sub-secondinteractive queries at a fraction of the cost of other existing services.
• MQube — MQube: Next-generation lending platform offering fast, automated mortgage solutions with real-time decisioning and built-in compliance.
• SoterAI — Transform workplace safety with AI-powered virtual loss control. Conduct audits in hours, analyze claims automatically, and provide insureds with comprehensive risk reduction tools.

Portfolio highlights

• Convelio — Convelio is a global logistics startup specialized in bulky, fragile and high-value items.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.
• Epoch Biodesign — Mellizyme Biotechnology is currently operating in stealth.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• CARV — CARV enables AI Beings to live, evolve, and govern as sovereign intelligences on-chain; not as tools, but as beings that act, learn, and lead.
• Nest Wallet — A Wallet Built for Traders

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Portfolio highlights

• Clique — At Clique, we revolutionize the development of TEE/MPC-enabled protocols and applications, offering unparalleled confidentiality, verifiability, and cost-efficiency.
• Proxima — At Proxima, we aim to push the boundaries of interactive entertainment by blending innovative technology with deep artistry. We believe in the magic of exploration, the power of creativity, and the strength of human connection that form the very foundation of our gaming experiences.
• Intuition — Intuition provides decentralized infrastructure, developer tools, and applications enabling the creation of an open, flexible knowledge graph enhancing the quality and availability of social knowledge.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Exabits AI — Exabits' network of GPUs ranges from consumer-grade to H100s, offering the most cost-effective compute because we are obsessed with innovating performance.

Portfolio highlights

• Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
• Rover — Rover is a liquid staking protocol on Botanix that exchanges Bitcoin for rovBTC.
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• Rhuna — Rhuna is an AI and blockchain platform that transforms event management with NFT ticketing and token rewards.
• Lympid — We believe that anyone should have access to the amazing opportunities found on the blockchain, from DeFi protocols (aave, compound, yearn…) to Crypto Indexes, there's so much to discover! At Lympid you will be able to do it all easily in the same app, and directly through EUR.
• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth