Top 50 Startup Investors in Panama in May 2026

Portfolio highlights

• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Joystream — Joystream is a block chain-based, decentralized video platform.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• Aark — Trade crypto perpetuals with up to 1000x leverage, zero gas fees, and an industry-low 0.01% trading fee. Earn payback on losses with VIP rewards. RWA & altcoin perps on Arbitrum. Backed by OKX Ventures.
• Itheum — As we enter the web3 and metaverse era; Itheum unlocks data silos and generates new value for your data.
• Fanable — Fanable is a Web3 marketplace specialized in Pokémon, comic books, and collectibles, allowing users to purchase, sell, and engage with their favorite products in both physical and digital forms.

Portfolio highlights

• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
• AlchemyNFT — AlchemyNFT is a non-fungible token (NFT) service.
• StakeStone — Discover the Autonomous Neo Bank redefining finance. Earn bank-grade yield, make borderless payments, and power intelligent money movement for humans, AI, and machines.

Portfolio highlights

• myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Evolv — Evolv is equipping brands with the technology to create immersive experiences for their customers.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• BluWhale — BluWhale's mission is to leverage AI and ML to allow game developers to focus on ways to improve the game rather than wrangling and making sense of astronomical amounts of data. BluWhale's smart automation will do the heavy lifting usually reserved for data analysts and data scientists all in the background, and surface actionable insight

Portfolio highlights

• SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
• Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.
• Eizper Chain — Eizper Chain is a blockchain action online multiplayer role-playing game that celebrates adventure and arena battle.

Portfolio highlights

• Metatheory — Metatheory Inc. is an interactive technology and entertainment company building Web3 games, interactive content, social experiences, and other community-driven adventures. Metatheory’s mission is to inspire imagination by connecting people worldwide through immersive worlds built on cross-generational IP.
• Pagos Solutions — Get real-time payment data detecting issues, trends, and opportunities plus intelligent payment solutions for optimizing payment performance.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• tread.fi — Explore tread.fi's institutional-grade trading platform designed to seamlessly integrate into your workflow, automate trade execution, and minimize slippage. Learn more.
• Ledger Works — Blockchain consumers face significant and increasing cyber-crime. And Web3 security efforts focus on DeFi providers, not retail users. A crypto account holder should be able to receive the same fraud alerts and protection they have come to expect from their bank or credit card accounts. Our service provides account notification and cyber-crimeprotection to Crypto account holders.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Everlyn — Everlyn is a Web3 video AI model that generates a decentralized infrastructure layer for autonomous video.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Cold River Games — Crystalfall is an upcoming free online action RPG with customizable skills and an endless endgame, set in a steampunk world.

Portfolio highlights

• Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
• GAM3S.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Snackclub — Learn more about play to earn games

Portfolio highlights

• Zuki Moba — The First E-Sports Game Empowering Gamers | Zuki Moba
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.

Portfolio highlights

• GAM3S.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Flappy Bird — Flappy Bird Foundation is to uphold the Flappy Bird intellectual property and further the Flappy Bird heritage. The Foundation accurately restores our vintage and nostalgic gameplay while adding new features to give back to the worldwide fan base that started the craze.
• Community Labs — Community Labs is a software development company and venture studio focused on accelerating developer tools, use cases, and adoption of Arweave and AO.

Portfolio highlights

• Crowdz — Make accounts receivables a thing of the past with a competitive invoice auction for selling your invoices with invoice financing
• Glamplus — Glamplus is a SAAS-enabled beauty marketplace for salons and spas in the SMB segment. Glamplus customized to suit salon,s needs. Glamplus offers Hassle-free digital appointment tracking, invoicing, customer engagement, revenue management & much more.
• Klaar — Klaar eliminates the stress and bias of performance management with timely AI-powered insights that help teams identify areas for improvement, make data-driven decisions, and ultimately drive better performance & careers.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Hashflow — Tight spreads. Zero slippage. MEV-resistant.
• Joystream — Joystream is a block chain-based, decentralized video platform.

Portfolio highlights

• IndiGG — IndiGG is an NFT based play-to-earn game in the web3 frontier. IndiGG is the India sub-decentralized autonomous organization(subDAO) of YGG.
• Shards — Shards is a free-to-use SDK for game studios that boosts in-game engagement and revenue by allowing players to create, fractionalize and trade in-game guilds.
• Delabs Games — At Delabs Games, we want to create fun games that last a thousand years.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Euclid Protocol — Euclid creates a chain agnostic liquidity layer that allows any application to integrate and swap against an efficient market to provide the best user experience for users.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Gata — Gata uses data technology to develop superintelligence and to ensure its alignment with human objectives.
• Algebra.Finance — Algebra.Finance is the Financial Services.

Portfolio highlights

• Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
• Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.
• Layer Social Labs — A home for global companionship and endless entertainment. Post More, Play More, Earn More.

Portfolio highlights

• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.

Portfolio highlights

• Splyce Finance — dETF protocol. Permissionless, on-chain index- and yield ETFs.

Portfolio highlights

• Hybrid — Hybrid is a fintech company that offers a decentralized central AI tool with Web3's ecosystem of AI experts, agents, and data.
• Ajuna Network — Ajuna Network is a decentralized ecosystem for gamers and creators.
• Liquorice — Liquorice is a developer of a DeFi protocol that combines one-sided loan pools with a MEV-free trading engine.

Portfolio highlights

• VAST — VAST is an artificial intelligence business that develops and manufactures general-purpose 3D big models. Its goal is to develop a popular 3D content production tool, a 3D user-generated content platform, and utilize 3D space to enhance user experience.
• ENCOS — ENCOS is a developer of high-performance robot integrated joint modules. The company focuses on matters of embodied intelligence, with robot reduction motors as its main business.
• LeXiang Intelligence — LeXiang Intelligence is a robotics company that specializes in the development of intelligent consumer-grade robots.

Portfolio highlights

• SolRazr — SolRazr is the first decentralized developer ecosystem for Solana, offering Launchpad, Accelerator, and Developer Tools.
• Exotic Markets — Exotic Markets bring wealth management and structured products out of the bank and in the decentralized finance world. Exotic Markets Maximise the investments with simple and sustainable products.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• GAIB — GAIB is the economic foundation for the future of artificial intelligence and computers. GAIB is a crypto-AI platform under development that tokenize GPUs, making AI computing—the processing power required to train and run AI models—more accessible.
• Yala — Yala operates a multi-token system and unlocks a thriving and interconnected DeFi ecosystem on Bitcoin​.

Portfolio highlights

• Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
• Stems Labs — community and platform for collaborative creativity
• MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Portfolio highlights

• TaxGPT — Looking for instant tax help? Meet TaxGPT, your AI-powered tax assistant. We simplify tax processes and maximize deductions. Try TaxGPT today!
• Asha Health — Asha Health is a Health Care Hospital offering AI Support to patients between visits.
• Pickle — Pickle lets your AI clone join zoom calls instead of you. It lip-syncs to your voice, so you don't have to turn on your camera. Create your Pickle and make your zoom call easy.

Portfolio highlights

• IRL — Groups, Chats, Events - Tap to see details
• Jerry — Jerry simplifies the expensive, frustrating, and time-consuming aspects of car ownership.
• Empowerly — We triple students' chances of getting into their top-choice colleges and universities. Get college counseling, essay editing, track university deadlines, and more. Learn more.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Caden — Caden is the world's first Zero-Party Data platform. We allow users to own and control their own personal data, make money off it, and share it with trusted consumer brands, while maintaining their privacy.
• Dashy Dash — Dashy Dash is a free community powered tool that makes it easy to manage invoices, discover new products & compare prices to help you save money.
• Vero Technologies — Vero Technologies is a Financial Services based company.

Portfolio highlights

• Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.
• Wild Moose — Wild Moose helps on-call developers more quickly identify the source of production incidents, by providing a conversational AI trained on their environment. This allows developers to delegate the search through logs and metrics to lightning-fast AI.
• The Wedding Company — The Wedding Company provides the best wedding services in India. Book end-to-end wedding planning services online with us and grab the best deals for your wedding, engagement, reception, and other events.

Portfolio highlights

• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Composable Corp — Composable Corp is a blockchain financial application developer.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.

Portfolio highlights

• Portal to Bitcoin — The only custody-less interoperability protocol for Bitcoin. Swap native BTC, Ordinals, Runes with L2s and L1s
• Acta Finance — Acta Finance develops a complete DeFi ecosystem, EVM compatible, able to deploy and integrate EVM compatible networks.
• Monarch Wallet — As part of this journey, we will discontinue our wallet services effective July 1, 2024.

Portfolio highlights

• Demole — Demole is a play to earn NFT gamification platform.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Radom — A Decentralised Network for Coordination of Cloud Applications and Connected Assets

Portfolio highlights

• XOCIETY — The XOCIETY metaverse is being developed by a well-established team of over 50 developers with decades of experience in the tech and web2 gaming fields.
• The FishVerse — FishVerse combines GameFi, AI, and blockchain technology, allowing players to fish in a dynamic open environment from their own homes.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• Gamium — Gamium is a Web3 and Metaverse technology company building the truly Decentralized Social Metaverse.
• Lympid — We believe that anyone should have access to the amazing opportunities found on the blockchain, from DeFi protocols (aave, compound, yearn…) to Crypto Indexes, there's so much to discover! At Lympid you will be able to do it all easily in the same app, and directly through EUR.
• Alliance Games — Build Beyond Limits. Multiplayer for the Next, Decentralized Era.

Portfolio highlights

• Starbots — Starbots is Solana's first-ever battle NFT game.
• Linear — Linear allows the user to manage software development and track bugs. Built for speed and efficiency.The founders started Linear from their own frustrations building software projects in successful high-growth companies like Airbnb, Coinbase and Uber. The founders wanted to create the tools that focus us and its team in making progress, not getin the way. Tools that are fast and efficient. Speed and performance were the main things Linear focuses on early on and keep focusing on that.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• ZAP — ZAP offers a reputation-based token distribution protocol that supports fair rewards for user contributions within the Blast ecosystem. It enables users to participate in various projects through missions and seamless investment options. Additionally, ZAP is expanding its services to other blockchains and developing tools to simplify access toventure-capital-backed projects.
• Galaxis — Galaxis maintains an engagement platform that aims to transform and strengthen the relationship between creators and their communities. The company's platform assists creators by injecting simple NFTs with unique utilities that can expand and alter.
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.

Portfolio highlights

• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
• Pixelverse — Pixelverse is a blockchain-based, pixelated P2E game.
• Mavryk Dynamics — Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Xion Finance — Xion Finance is the easiest way to start earning a passive income on your crypto. Earn interest, shop products or yield farm with a novel one click to DeFi protocol. Get Started Today!
• QANplatform [QAN blockchain platform] — QANplatform is the quantum-resistant Layer 1 hybrid blockchain where developers can code web3 solutions in any language on top of the QAN blockchain platform.

Portfolio highlights

• Sidus Heroes — gaming company
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.
• CryptoVsZombie — CryptoVsZombie is the ultimate crypto tower defence in which players are required to multitask in both offensive and defensive modes.

Portfolio highlights

• Capx — Capx's mission is to accelerate the flow of capital through the private markets, thereby enhancing global capital allocation. With secondary market and enterprise solutions, Capx combines high-quality collections of opportunities with efficient access for institutions and individual investors.
• RiskLayer — RiskLayer is an economic security middleware for DeFi and providing services and validating Creating positive feedback loops.
• GoPlus Security — GoPlus offers holistic AI and Web3 security. Leveraging AI-powered audits and APIs, we safeguard assets and operations across the blockchain and AI landscapes.

Portfolio highlights

• Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
• Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!