Top 40 Health Care Startup Investors in South Africa (June 2026)

Portfolio highlights

• mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
• Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.

Portfolio highlights

• MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• AURA — A South African cloud-based security and safety startup .

Portfolio highlights

• Fixit45 — Fixit45 also provides fleet management, auto parts sourcing and delivery, auto care, refurbishment and upgrades, repair financing, and mechanic workshop software as well as pre-purchase inspections, underlying these with moderation for compliance and accountability.
• Gigmile — Gigmile provides financial services. They provide gig workers with core services and an affordable lease on productive assets that is tailored to their earnings to enable them to succeed in the mobility industry as entrepreneurs.
• HomecomingEx — Homecoming Revolution is a pan-African recruitment firm for global African professionals. We specialise in headhunting & placing global African talent.

Portfolio highlights

• Flow — Flow enables automated social media advertising for the real estate industry, providing high volumes of quality property leads and brand building.
• hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.

Portfolio highlights

• PsyLabs — PsyLabs focuses on cultivating and producing trippy active pharmaceutical ingredients and isolates for use in research, clinical trials, and medication development.

Portfolio highlights

• Vesper — Vesper is an electrical and electronic manufacturing company that specializes in microphones, piezoelectric, and audio. The company is driven by a mission is to deliver voice-powered products to every market, around the world. Vesper was founded in 2009 and headquartered in Boston, Massachusetts.
• Medrhythms — Pioneering Next-Generation Digital Therapeutics to Improve Walking  
• Noise — Buy latest Noise smart watches, wireless earbuds, BT neckband earphones, wireless headphones, speakers and smart watch accessories online at best prices in India.

Portfolio highlights

• Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
• CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
• RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.

Portfolio highlights

• YNMO — YNMO is the first Arabic/English digital solution that aims to improve the quality of care and educational services for individuals with special needs by allowing service providers such as schools, centers & clinics to design and monitor individualized treatment plans.
• Aanaab — Aanaab offers online courses in Arabic for teachers and educators to help them improve their skills in different areas including self-development, educational strategies, education techniques, and educational tools and techniques.
• HealTec — HealTec provides B2B healthcare rehabilitation manufacturing facility that enables the local production of medical prosthetics and other devices to serve Long-Term Care and rehabilitation patients.

Portfolio highlights

• HoneyCoin — HoneyCoin is a web3/web2 ecosystem of products built in a way that abstracts complexity and brings all the value of web3 and web2 to the forefront.
• Aether Bio — Aether uses its state of the art platform to rapidly engineer enzymes, enabling our customers to manufacture complex and novel products at fractional cost.
• Franc — Franc is the easiest way to save & invest. Our app doesn’t require any investment knowledge & our friendly risk quiz helps us understand how much investment risk is right for you. Users can start investing in less than 2 minutes. There is no minimum requirement & no paperwork. It is a seamless digital experience end-to-end. A usersimply chooses a goal, selects an investment strategy, verifies their identity & makes a deposit. Each user is recommended a personalised investment strategy for each investment goal, combining money market & index tracking ETFs. Our helpful calculators assist clients with their budgeting, retirement & targeted savings needs. We also provide free access to our online academy & fun financial literacy quizzes.We know saving is hard & investing can be scary, which is why we create savings groups & challenges so that users can encourage one another. We also run weekly competitions where users can stand a chance to win a cash prize that will boost their investments.

Portfolio highlights

• Contro — Weight Loss TreatmentHealth Coach Support

Portfolio highlights

• Motai —
• Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
• Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Portfolio highlights

• Immunocore — Immunocore is focused on the discovery and development of novel T cell receptor-based drugs to treat diseases with a high unmet need, including cancer and viral disease. The Company’s world-leading expertise in engineering T Cell Receptors (TCRs) and linking them to an antibody fragment (scFv) known as anti-CD3, has led to its first productcandidate, IMCgp100, entering clinical trials in patients with metastatic melanoma. The proprietary T Cell Receptor technology platform is well validated and can easily be manufactured for clinical and commercial supply in microbial systems.
• SeamlessHR — Africa's Leading HR & Payroll Software - Empowering African Businesses for Productivity and Profitability Through Technology.
• Aspen Pharmacare — Aspen is a global specialty and branded multinational pharmaceutical company with a presence in both emerging and developed markets

Portfolio highlights

• Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
• HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
• Raino Tech4Impact — Raino Tech4Impact is a social enterprise that leverages technology as an enabler to empower African communities. We have been deploying technology-driven solutions in agriculture and health, powered by renewable energy to achieve sustainability.

Portfolio highlights

• Zoundream — The Future of Infant Care
• Understanding Zoe — Understanding Zoe is a neuroaffirming application that turns every report and observation into an actionable step for a better connect.
• Neuraworx Medical Technology — Neuraworx Medical Technology is a neurotechnology company developing first-in-class bioelectronic solutions for brain health.

Portfolio highlights

• hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.

Portfolio highlights

• PopID — PopID is a software company that provides solutions for verifying an individual’s identity based on their face for applications such as loyalty, payment, and entry.
• Padiepal — Discover the Future of Digital Finance with Padiepal Transforming Digital Finance At Padiepal, we're on a mission to redefine the future of digital finance. With an ever-growing range of innovative services, we cater to the needs of individuals, businesses, and global merchants alike. Our objective is to provide seamless transactions andfinancial solutions that meet the demands of today's fast-paced digital world.Comprehensive Services for Everyone Our offerings are designed to empower users to manage their finances effectively. From dollar virtual accounts to international money transfers, we have services that enhance the user experience. Individuals can enjoy straightforward payment solutions, while businesses can utilize our robust tools to expand their operations globally. By combining technology with financial expertise, Padiepal facilitates smart financial decisions for everyone.Why Choose Padiepal? With a commitment to security and transparency, Padiepal is a trustworthy partner in your financial journey. Our user-friendly interface simplifies engaging with digital finance, making it accessible to all. Moreover, we continuously innovate and adapt our services to remain at the forefront of digital finance trends. Whether you’re a seasoned merchant or just starting your financial journey, Padiepal stands ready to support your goals.
• Shopware — Shopware is a trendsetting ecommerce platform to power your online business. Our ecommerce solution offers the perfect combination of beauty & brains you need to build and customize a fully responsive online store.

Portfolio highlights

• FitKey — FitKey is about helping you find and manage the fitness life that makes you happy, through discovering new classes, studios, and fitness activities. With easy online and mobile booking, FitKey keeps your routine interesting.
• TaxTim — Originally funded by Google in 2011, TaxTim is Africa's answer to Making Tax Easy. Answer simple questions one-by-one, in a friendly automated chat, and your tax return is done in minutes. TaxTim has 40% market share of the tax base in South Africa (~4.5m), and has deployed localised versions in Namibia and Nigeria as JVs with PwC previously.TaxTim is integrated with the local revenue service (SARS) for instant electronic tax submissions, and partners with some of SA's largest consumer brands - Airbnb, Momentum, Sanlam, Old Mutual, FNB eBucks - to provide tax services for free or at discount. TaxTim has several business models including B2C, B2B and B2B2C. TaxTim is a compelling and popular consumer brand, with a fully-developed, profitable broker/financial product leads ecosystem.
• Ekaya.com — Ekaya exists to make renting simpler, safer and more connected - for everyone.

Portfolio highlights

• Susu — Susu is a dynamic and innovative company that offers a wide range of health services for families in the African diaspora. Susu provides a complete offer on Preventive care, Medical treatments, Management of chronic diseases, and Authentic drugs.
• Kasha — Health products and household goods you want, delivered to where you are.
• Zuri Health — .ts-banner-image-1:hover .overlay{background-color:#ffffff} .ts-banner-image-2:hover .overlay{background-color:#ffffff} Popular categories Pharmacy Doctor at home Covid Labs & Diagonstics Wellness Telemed Show all Our Services PharmacyBuy both OTC and prescription medication and have it delivered to your doorstepLabs & DiagnosticsBook labs and Diagnostic tests and get your samples collected from the comfort of your home, hotel

Portfolio highlights

• Lumkani — AFFORDABLE ALARM SYSTEMS & INSURANCE FOR YOUR HOME OR BUSINESS Whether you are in a township, informal settlement, or suburb, we have the right protection for you. AFFORDABLE ALARM SYSTEMS & INSURANCE FOR YOUR HOME OR BUSINESS Whether you are in a township, informal settlement, or suburb ...
• Investsure — InvestSure is a technology company that uses its software to enable partner investment platforms to sell its unique Investment Indemnity (insurance) product to their clients. InvestSure provides a full set of APIs that trading platform developers can use to integrate the Investure Investment Indemnity product seamlessly and easily into theirwebsites and mobile applications. Once InvestSure technology is added to a trading platform, it enables users to buy insurance on their shares with a single click. The full process from buying to insurance to settling claims is fully automated.The Investment Indemnity product itself is a unique innovation; it is designed to protect to protect shareholders against any losses in share value caused by actual or perceived fraud committed by management. This enables investors to secure their investments. The cost of the product is low enough to not significantly reduce returns of investors where no insurance event occurs, but to provide significant downside protection where an insured event does occur.
• CompariSure — Custom, built-for-purpose service and sales chatbot solutions for financial services providers.

Portfolio highlights

• Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
• Trade Lenda — Trade Lenda: Access to Loans, Investments, Utility Payments, Credit Access, Insurance, and More! Unlock Opportunities to Earn, Invest, and Grow. Secure Personal or Business Loans Toda
• Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Portfolio highlights

• Mobiz — Supercharge your SMS marketing with dynamic, high-converting landing pages sent directly into the hands of your customers.
• onafriq — MFS Africa is the largest mobile money inter-operability hub in Africa, which connects mobile network operators across the continent through a single API. In addition to mobile remittance services, the MFS Africa API enables merchant payment, bulk payment, bank-to-wallet transfers, and an array of other cross border digital payments services.
• Sendmarc — Manage your organization's DMARC, SPF, and DKIM with world-class implementation services and support. All in one easy-to-use platform.

Portfolio highlights

• d6 — SCHOOLS Schools Communication Platforms and School Management Software COMMUNITIES Community & Internal Business Communication Platforms MEDIA Let your brand be seen Advertise on
• DataProphet — DataProphet offers production intelligence solutions for manufacturers. By combining human ingenuity with production data, we supercharge manufacturing excellence. Explore our Connect platform and expert services, trusted by industry leaders.
• Stone Three Venture Technology — We combine expert services with the power of machine learning to help our customers increase their productivity and safety.

Portfolio highlights

• Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
• Conservio — Discover and Book South Africa's best nature accommodations with Conservio. Book vetted accommodations, easy and safe to book online.

Portfolio highlights

• Contro — Weight Loss TreatmentHealth Coach Support
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.

Portfolio highlights

• I-G3N — I-G3N is a South African developer of lithium-ion batteries. The company’s core market is on stationary storage in conjunction with Solar PV and focuses on superior products and on the incorporation of the latest technologies to battery functionality. One of the key focus areas is on exporting to the SADC region and the rest of Africa, asextraordinary opportunities exist on the rest of the continent, especially in the development of mini and micro-grids to impact development.
• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.

Portfolio highlights

• 3X4Genetics — Scientifically-robust nutrigenomics (personalised nutrition guided by your own genetic stack). Practitioner education & genomic reporting
• Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling
• SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.

Portfolio highlights

• Pumpkn — Need reliable funding? We provide quick loans and capital tailored for Agriculture businesses in South Africa. Grow your business with Pumpkn. Apply now!
• JOBJACK — The JOBJACK platform automates the entry-level recruitment process, so hiring your deskless staff is easy, quick and simple. Our proprietary entry-level psychometric assessments, along with built-in credit and risk checks, help our customers identify the right talent to grow their businesses.
• The Awareness Company — We use data to tell stories that are useful to humans.

Portfolio highlights

• Jerry — Jerry simplifies the expensive, frustrating, and time-consuming aspects of car ownership.
• Kyash — Kyash is a fintech platform providing mobile banking services with full-stack banking technology currently offering digital wallet app. It has built proprietary full-stack banking infrastructure from the ground up to offer mobile-first consumer-facing digital wallets in Japan.The platform offers online payment and personal remittance apps underthe Kyash service name, and issues prepaid cards that can be used at Visa merchants. It also provides a new card that is available in three colors, navy, silver, and pink and adopts a simple design with card numbers and card names placed on the back. The first Visa card in Japan with an IC chip and contactless payment function that has no card number on the front side.Kyash was founded on January 23, 2015, and is based in Tokyo, Japan.
• Payhere — Payhere is a fintech company that provides card terminals and online payment gateway services for multiple industries.

Portfolio highlights

• Raptures — Raptures is a global digital storytelling platform & studio network creating original and industry leading webtoons, comics and animations.
• Matta — Matta is a B2B platform offering a comprehensive, detailed marketplace for sourcing chemicals and materials efficiently and reliably
• Prembly — Leading provider of identity verification, KYC/KYB compliance, AML screening, fraud detection, and background check solutions. Trusted by businesses across Africa and globally for secure, real-time verification.

Portfolio highlights

• LIQID Medical — Glaucoma Implants in South Africa. Liqid Medical is a medical device company focusing on addressing the need for effective, long-rerm solutions for glaucoma treatment.

Portfolio highlights

• Jahazii — Jahazii provides an online platform for workforce management. The company offers tools for storing and organizing employee records in one system. It manages scheduling, attendance tracking, and timesheets for different types of workers. The platform connects attendance and payroll functions to support salary processing. It allows employers toautomate payroll calculations and salary disbursement. The company also provides earned wage access, letting employees receive part of their pay before payday.
• TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
• The Awareness Company — We use data to tell stories that are useful to humans.

Portfolio highlights

• Adbot — Adbot makes Google ads easy. Start a Google Ad Campaign and get results!
• Koa Academy — Koa Academy is on the cutting edge of online schooling in South Africa! We offer small classes, quality educators, and individualized, engaged online learning.
• Brown and Ayo — Brown and Ayo have provided customers with an extensive online marketplace of natural hair extensions created to mimic black natural hair textures. The company prides itself in bringing innovative and well-loved products to the SA black woman consumer.

Portfolio highlights

• Ann-Connect — Ann-Connect is an EdTech SaaS for learning, teaching, exams and assessments rolled into an all-in-one education platform.Founded in 2021 by Bonginkosi Mabaso, Nexa was born from a real problem: students missing exams and learning opportunities because of unreliable internet. Our mission is simple: make online education accessible to everystudent, regardless of connectivity or background. Today, Nexa is trusted by universities, training institutions, and professional bodies across South Africa, with partnerships that give access to more than 450,000 learners. One workspace. All your education tools: - Nexa ExamCore: Offline exam tool where students can access, write, and submit online exams even without internet. - Nexa Invigilator: Invigilation tool designed to monitor for online exams. - Nexa Invigilator Venue-based – Proctoring for physical/venue-based exams for schools, corporates & teams. - Nexa Room – Low-bandwidth video conferencing just like MS Teams but designed for teaching and learning, with AI-driven student engagement tracking. - Integrations – Seamless connection with Learning Management Systems (LMS), plagiarism checkers, and other education tools — all in one place. Recognised with awards from TIA, ABSA, and the Royal Academy of Engineering (UK), Nexa is shaping the future of global education by making it inclusive, resilient, and accessible everywhere. Ready to experience THE platform for inclusive learning? Visit ann-connect.com and join us in building education without limits.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
• Ownedby Technologies — Ownedby is an interactive asset management solution for business and household assets, focused on appliances and devices, giving these unique identity that is traceable online, yet linked to and controlled by owners.

Portfolio highlights

• Pargo — Pargo is a convenient logistics solution that lets you collect and return parcels at Pargo parcel points throughout the country when it suits you best.
• Synatic — Synatic is a unified platform that enables your business to integrate and automate systems and services without sacrificing enterprise features and security.
• Peach Payments — Get Peach as your Payment Gateway and Grow your ecommerce. Process online payments with Visa, Mastercard, Debit Orders, EFT payments, and subscriptions. Plugins for Wix, Shopify, WooCommerce.

Portfolio highlights

• BusyMed — BusyMed connects independent local pharmacists to their communities using the BusyMed App. Get your medication delivered to your door in 60 minutes. Shop. Pay. Delivered.

Portfolio highlights

• Tugende — Tugende helps motorcycle taxi drivers own their own motorcycles in eighteen months or less instead of renting indefinitely. Ownership significantly increases income, job security and road safety.
• Jumba — Jumba is the trusted digital partner for hardware stores. Through tech, we support hardware stores to grow. Get cement at unbeatable prices. Access cement LPOs even at midnight. Get inventory on credit through Jengwa.
• Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.

Portfolio highlights

• FairPlay24 — The world's first Fairness-as-a-Service company, offering tools that embed fairness into AI decision-making and reducing algorithmic bias.
• GoodLife Fitness — From personal training to our fitness classes, the goal of every GoodLife Fitness club and gym is to help all Canadians live a fit and healthy good life.
• Project Prometheus — Project Prometheus develops AI tools designed to learn from and interact with the physical world, rather than just process digital data. Its product efforts target engineering and manufacturing in aerospace, automotive, and computing sectors, using AI to optimize design, production, and performance.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• Kinish — Kinish is a company leading a revolution in dairy products. To achieve environmentally friendly and delicious dairy products, we are developing a special rice variety that produces milk proteins.
• Kwahuu Ocean — Kwahuu Ocean develops sustainable squid farming systems.
• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.