Top 35 Health Care Startup Investors in South Africa in May 2026

Portfolio highlights

• NjiaPay — Payments-as-a-Service platform that will streamline your operations and elevate your online payments across the African continent.
• Talk360 — Talk360 is an easy-to-use calling app that helps people make affordable international calls to any mobile and landline number. They believe that reliable communication and digital services must be affordable and accessible to everyone, regardless of someone's background. Especially people in emerging countries in Africa, who often need theseservices the most, do not always have the necessary banking possibilities. To bridge this distance, Talk360 will launch the world's first single checkout platform for Africa. This platform will combine all locally available payment methods and currencies across Africa, together with over 1.25 million cash points of sales, and will eventually be available to other companies as well. This means that 500 million Africans will be able to purchase digital services they never had access to before.
• Right Now Response — The future of repairs starts soon. Counting down to smarter tracking in 2025! There are perks to working 24/7, 365 days a year... Like launching the future of repairs ahead of schedule!

Portfolio highlights

• Billboxx — Manage payables, receivables, financing and banking in one platform.
• mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.

Portfolio highlights

• Zazuu — Zazuu is a platform for sending money across the border.
• Gigmile — Gigmile provides financial services. They provide gig workers with core services and an affordable lease on productive assets that is tailored to their earnings to enable them to succeed in the mobility industry as entrepreneurs.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.

Portfolio highlights

• Vesper — Vesper is an electrical and electronic manufacturing company that specializes in microphones, piezoelectric, and audio. The company is driven by a mission is to deliver voice-powered products to every market, around the world. Vesper was founded in 2009 and headquartered in Boston, Massachusetts.
• Medrhythms — Pioneering Next-Generation Digital Therapeutics to Improve Walking  
• Noise — Buy latest Noise smart watches, wireless earbuds, BT neckband earphones, wireless headphones, speakers and smart watch accessories online at best prices in India.

Portfolio highlights

• Tripplo — Tripplo is a platform to automate and optimise operations for transporters, cargo owners and cargo brokers.
• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Sourcefin — Quick PO funding & invoice discounting with expert support. Get funded in 48 hours. No hidden fees. We've helped 1000s of SA SMMEs. Apply now.

Portfolio highlights

• FitKey — FitKey is about helping you find and manage the fitness life that makes you happy, through discovering new classes, studios, and fitness activities. With easy online and mobile booking, FitKey keeps your routine interesting.
• TaxTim — Originally funded by Google in 2011, TaxTim is Africa's answer to Making Tax Easy. Answer simple questions one-by-one, in a friendly automated chat, and your tax return is done in minutes. TaxTim has 40% market share of the tax base in South Africa (~4.5m), and has deployed localised versions in Namibia and Nigeria as JVs with PwC previously.TaxTim is integrated with the local revenue service (SARS) for instant electronic tax submissions, and partners with some of SA's largest consumer brands - Airbnb, Momentum, Sanlam, Old Mutual, FNB eBucks - to provide tax services for free or at discount. TaxTim has several business models including B2C, B2B and B2B2C. TaxTim is a compelling and popular consumer brand, with a fully-developed, profitable broker/financial product leads ecosystem.
• Ekaya.com — Ekaya exists to make renting simpler, safer and more connected - for everyone.

Portfolio highlights

• Susu — Susu is a dynamic and innovative company that offers a wide range of health services for families in the African diaspora. Susu provides a complete offer on Preventive care, Medical treatments, Management of chronic diseases, and Authentic drugs.
• Kasha — Health products and household goods you want, delivered to where you are.
• Zuri Health — .ts-banner-image-1:hover .overlay{background-color:#ffffff} .ts-banner-image-2:hover .overlay{background-color:#ffffff} Popular categories Pharmacy Doctor at home Covid Labs & Diagonstics Wellness Telemed Show all Our Services PharmacyBuy both OTC and prescription medication and have it delivered to your doorstepLabs & DiagnosticsBook labs and Diagnostic tests and get your samples collected from the comfort of your home, hotel

Portfolio highlights

• Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
• Godochurch — GoDoChurch is a cloud-based church administration software which is designed to assist Christian churches and ministries with managing members, Sunday services, events, communications, and more. The system is made up of a base package, covering messaging, news, ministries, lists, church roles, services, events, and growth paths, with additionalmodules for managing follow-ups, groups, and Kids church.
• Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Portfolio highlights

• Adbot — Adbot makes Google ads easy. Start a Google Ad Campaign and get results!
• Koa Academy — Koa Academy is on the cutting edge of online schooling in South Africa! We offer small classes, quality educators, and individualized, engaged online learning.
• Brown and Ayo — Brown and Ayo have provided customers with an extensive online marketplace of natural hair extensions created to mimic black natural hair textures. The company prides itself in bringing innovative and well-loved products to the SA black woman consumer.

Portfolio highlights

• Pargo — Pargo is a convenient logistics solution that lets you collect and return parcels at Pargo parcel points throughout the country when it suits you best.
• Synatic — Synatic is a unified platform that enables your business to integrate and automate systems and services without sacrificing enterprise features and security.
• Peach Payments — Get Peach as your Payment Gateway and Grow your ecommerce. Process online payments with Visa, Mastercard, Debit Orders, EFT payments, and subscriptions. Plugins for Wix, Shopify, WooCommerce.

Portfolio highlights

• Aerobotics — Powerful insights for precision growing and crop insurance
• CompariSure — Custom, built-for-purpose service and sales chatbot solutions for financial services providers.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• BusyMed — BusyMed connects independent local pharmacists to their communities using the BusyMed App. Get your medication delivered to your door in 60 minutes. Shop. Pay. Delivered.

Portfolio highlights

• Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
• Trade Lenda — Trade Lenda: Access to Loans, Investments, Utility Payments, Credit Access, Insurance, and More! Unlock Opportunities to Earn, Invest, and Grow. Secure Personal or Business Loans Toda
• Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Portfolio highlights

• Ensoma — Ensoma is expanding the reach of the curative power of genomic medicine by pioneering a next-generation in vivo approach using its Engenious™ vectors. Ensoma’s vectors are designed to deliver a diverse range of gene modification technologies without the need for stem cell collection or prior myeloablative conditioning (e.g., chemotherapy). As aresult, Ensoma’s therapies can be delivered as a single injection in a diverse range of settings, including outpatient and settings where access to sophisticated healthcare systems may be limited.
• Aspen Pharmacare — Aspen is a global specialty and branded multinational pharmaceutical company with a presence in both emerging and developed markets
• NILO Therapeutics — A neuronal circuit regulates the immune system. We're targeting it to treat autoimmune and inflammatory diseases.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.

Portfolio highlights

• Mobiz — Supercharge your SMS marketing with dynamic, high-converting landing pages sent directly into the hands of your customers.
• onafriq — MFS Africa is the largest mobile money inter-operability hub in Africa, which connects mobile network operators across the continent through a single API. In addition to mobile remittance services, the MFS Africa API enables merchant payment, bulk payment, bank-to-wallet transfers, and an array of other cross border digital payments services.
• Sendmarc — Manage your organization's DMARC, SPF, and DKIM with world-class implementation services and support. All in one easy-to-use platform.

Portfolio highlights

• hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.

Portfolio highlights

• Octiv — Turbocharge your fitness business, grow your community and build your brand with Octiv's leading Gym Management Software.
• Outsized — Independent talent for enterprise clients and consulting firms in Asia-Pacific, Africa, and the Middle East.
• Simera Sense — Simera Sense develops camera control electronics for optical payload and Cubesat imager solutions.

Portfolio highlights

• AT&T — AT&T is a telecommunications company that provides wireless communications, local exchange, and long-distance services for consumers and businesses in the United States and internationally.The company offers its services in two segments: wireless and wireline. Its wireless segment offers various wireless voice, data, text, and otherservices. This segment sells various handsets, wirelessly-enabled computers, and wireless data cards for personal computers through its owned stores, agents, and third-party retail stores. It also sells accessories comprising carrying cases, hands-free devices, batteries, battery chargers, and other items to consumers as well as to agents and third-party distributors. As of December 31, 2013, this segment served approximately 110 million wireless subscribers.The company’s wireline segment provides data services such as switched and dedicated transport, DSL internet access, network integration, managed web hosting, packet, and enterprise networking services as well as local, interstate, and international wholesale networking capacity solutions to other service providers. This segment also offers voice services consisting of local and long-distance services; wholesale switched access services to other service providers; and outsourcing and integration services as well as CPE and government-related services. This segment has served approximately 12 million retail consumers, 10 million retail businesses, and 2 million wholesale access lines.AT&T is headquartered in Dallas, Texas.
• FairPlay — The world's first Fairness-as-a-Service company, offering tools that embed fairness into AI decision-making and reducing algorithmic bias.
• Albert Invent — 1000’s of scientists, technicians, and engineers across 30+ countries rely on Albert’s end-to-end Cloud Platform to accelerate the innovation of new materials. With Albert, R&D organizations get the data insights and tools needed to increase speed to market, automate regulatory compliance, and heighten the impact of new products.Built fromthe ground up for the chemical and material science industry, the Albert Platform connects R&D processes and creates a single data source of truth across the R&D organization. Augmented with AI, machine learning and a comprehensive materials database, key platform functionality includes inventory, worksheets, workflows, tasks, and more. www.albertinvent.com

Portfolio highlights

• Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
• HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
• Raino Tech4Impact — Raino Tech4Impact is a social enterprise that leverages technology as an enabler to empower African communities. We have been deploying technology-driven solutions in agriculture and health, powered by renewable energy to achieve sustainability.

Portfolio highlights

• Hohm Energy — We make the process of going solar simple. Generate your free, custom solar proposal and get matched with an accredited solar provider in under 5 mins.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
• Conservio — Discover and Book South Africa's best nature accommodations with Conservio. Book vetted accommodations, easy and safe to book online.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• Kinish — Kinish is a company leading a revolution in dairy products. To achieve environmentally friendly and delicious dairy products, we are developing a special rice variety that produces milk proteins.
• Kwahuu Ocean — Kwahuu Ocean develops sustainable squid farming systems.
• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• Contro — Weight Loss TreatmentHealth Coach Support
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.

Portfolio highlights

• Prosoma — Prosoma was born out a need to provide more comprehensive care for cancer patients. We have found a fundamental lack of access to psychological care for patients who not only have to face a life-altering disease and treatment, but also crucially have a different set of needs than other psychological patients. Barriers to accessing psychologicalcare often include low numbers of therapists and clinicians in the area, financial or geographical limitations, and the general wellbeing of patients preventing them from attending meetings. All of these issues can be solved by modern technology.By using VR as part of, or when necessary, an alternative to traditional psychological treatment, we can reach patients that would otherwise be left without any support. They can use our tool at home or in the clinics whilst undergoing pharmacological treatment and chemotherapy.We hope to provide patients with a tool that will help them manage stress, cope with the burden of cancer, and eventually improve their quality of life.
• Lifeyear — Digital-first heart care. At scale.
• CareLoop Health — CareLoop, an innovation emerging from the University of Manchester, furnishes patients with digital support resources while simultaneously providing healthcare professionals with the means to monitor and track patient symptoms.

Portfolio highlights

• I-G3N — I-G3N is a South African developer of lithium-ion batteries. The company’s core market is on stationary storage in conjunction with Solar PV and focuses on superior products and on the incorporation of the latest technologies to battery functionality. One of the key focus areas is on exporting to the SADC region and the rest of Africa, asextraordinary opportunities exist on the rest of the continent, especially in the development of mini and micro-grids to impact development.
• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.

Portfolio highlights

• Taager — Taager is a social e-commerce platform enabling online merchants with end-to-end logistics.
• PALM — PALM rewards users for consistency and advancement by fusing contemporary behavioral nudges with conventional investment techniques. To assist customers in achieving their objectives, PALM selects the best asset allocations among asset types, such as fixed income, stocks, and precious metals. PALM improves savings value and lowers out-of-pocketexpenses by fusing exclusive offers from an expanding merchant network with strong investment returns.
• Hohm Energy — We make the process of going solar simple. Generate your free, custom solar proposal and get matched with an accredited solar provider in under 5 mins.

Portfolio highlights

• 3X4Genetics — Scientifically-robust nutrigenomics (personalised nutrition guided by your own genetic stack). Practitioner education & genomic reporting
• Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling
• SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.

Portfolio highlights

• Yakeey — Yakeey is an end-to-end transactional marketplace that radically simplifies the experience of buying, selling and renting real estate.We leverage on data and technology to connect all real estate market players through a state of the art platform, create a chain of trust and powerful network effects and accelerate transactions.Yakeey is builton a community of real estate advisors, YakeeyPRO, to deliver a continuous professional and tailored service at every step of the transaction.
• Hub2.Io — Welcome to HUB2, the leading FINTECH startup in interoperability and payment infrastructure in Francophone Africa. We are proud to work with all financial industry players in Africa who need stable and high-performing infrastructure, and contribute to their success.
• Affinity — Join over 125,000 who trust the Affinity mobile app to manage their banking needs, from savings to payments, as well as instant loans

Portfolio highlights

• FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
• Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
• Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.

Portfolio highlights

• JOBJACK — The JOBJACK platform automates the entry-level recruitment process, so hiring your deskless staff is easy, quick and simple. Our proprietary entry-level psychometric assessments, along with built-in credit and risk checks, help our customers identify the right talent to grow their businesses.
• Kena Health — Talk to a nurse, doctor or mental health professional on your smartphone with the Kena Health App. Affordable primary healthcare for South Africans. Download Now.

Portfolio highlights

• Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
• CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
• RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.

Portfolio highlights

• Fordefi — The MPC wallet platform and Web3 gateway from Fordefi allow institutions to connect to dApps across multiple chains while keeping digital assets secure. Fordefi is the first institutional MPC wallet and security platform designed for decentralised finance. It provides MPC key management, self-service DeFi policy controls, time-of-transaction smartcontract insights, transaction simulation, and risk alerts.
• Padiepal — Discover the Future of Digital Finance with Padiepal Transforming Digital Finance At Padiepal, we're on a mission to redefine the future of digital finance. With an ever-growing range of innovative services, we cater to the needs of individuals, businesses, and global merchants alike. Our objective is to provide seamless transactions andfinancial solutions that meet the demands of today's fast-paced digital world.Comprehensive Services for Everyone Our offerings are designed to empower users to manage their finances effectively. From dollar virtual accounts to international money transfers, we have services that enhance the user experience. Individuals can enjoy straightforward payment solutions, while businesses can utilize our robust tools to expand their operations globally. By combining technology with financial expertise, Padiepal facilitates smart financial decisions for everyone.Why Choose Padiepal? With a commitment to security and transparency, Padiepal is a trustworthy partner in your financial journey. Our user-friendly interface simplifies engaging with digital finance, making it accessible to all. Moreover, we continuously innovate and adapt our services to remain at the forefront of digital finance trends. Whether you’re a seasoned merchant or just starting your financial journey, Padiepal stands ready to support your goals.
• CoPilot — CoPilot is pioneering Assisted Commerce for big-ticket purchases – starting with cars. You are the one spending the money - shouldn't you have an expert on your side? We founded CoPilot to make that a reality. For the average car buyer, who is not a car expert or enthusiast, car shopping can be a time consuming, frustrating process that leavespeople feeling alone and disadvantaged. CoPilot is changing this dynamic. Like a trusted friend who is knowledgeable about cars, knows where to look and what to buy, CoPilot provides car shoppers with an expert partner who empowers them to discover the perfect car at the best possible price with ease and confidence.

Portfolio highlights

• Contro — Weight Loss TreatmentHealth Coach Support

Portfolio highlights

• Posh — Event marketing made easy.
• Zepto — India's fastest grocery delivery service.
• Payhere — Payhere is a fintech company that provides card terminals and online payment gateway services for multiple industries.