Top 10 Medical Device Startup Investors in South Africa (June 2026)

Portfolio highlights

• MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• AURA — A South African cloud-based security and safety startup .

Portfolio highlights

• Flow — Flow enables automated social media advertising for the real estate industry, providing high volumes of quality property leads and brand building.
• hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.

Portfolio highlights

• mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
• Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.

Portfolio highlights

• Vesper — Vesper is an electrical and electronic manufacturing company that specializes in microphones, piezoelectric, and audio. The company is driven by a mission is to deliver voice-powered products to every market, around the world. Vesper was founded in 2009 and headquartered in Boston, Massachusetts.
• Medrhythms — Pioneering Next-Generation Digital Therapeutics to Improve Walking  
• Noise — Buy latest Noise smart watches, wireless earbuds, BT neckband earphones, wireless headphones, speakers and smart watch accessories online at best prices in India.

Portfolio highlights

• Affinity — Affinity is a financial solutions company that provides financial inclusion, advisory, and literacy services.
• ToumAI Analytics — ToumAI Analytics is a software development company providing voice analytics, real-time analytics, and reporting services.
• PBR Life Sciences — A cloud-based real-world, non-observational pharmacy sell-out data

Portfolio highlights

• Atreca — Atreca is a biopharmaceutical that develops a technology to identify the set of antibodies produced during an immune response, without prior knowledge of an antigen. Its product candidate, ATRC-101, is a monoclonal antibody in preclinical development with a novel mechanism of action and target-derived from an antibody identified using its discoveryplatform.
• Immunocore — Immunocore is focused on the discovery and development of novel T cell receptor-based drugs to treat diseases with a high unmet need, including cancer and viral disease. The Company’s world-leading expertise in engineering T Cell Receptors (TCRs) and linking them to an antibody fragment (scFv) known as anti-CD3, has led to its first productcandidate, IMCgp100, entering clinical trials in patients with metastatic melanoma. The proprietary T Cell Receptor technology platform is well validated and can easily be manufactured for clinical and commercial supply in microbial systems.
• Schrödinger — Schrödinger’s industry-leading computational platform facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas.Schrödinger is deeply committed toinvesting in the science and talent that drive its computational platform. Schrödinger was founded in 1990, has over 700 employees and is engaged with customers and collaborators in more than 70 countries. To learn more visit www.schrodinger.com.

Portfolio highlights

• I-G3N — I-G3N is a South African developer of lithium-ion batteries. The company’s core market is on stationary storage in conjunction with Solar PV and focuses on superior products and on the incorporation of the latest technologies to battery functionality. One of the key focus areas is on exporting to the SADC region and the rest of Africa, asextraordinary opportunities exist on the rest of the continent, especially in the development of mini and micro-grids to impact development.
• Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.

Portfolio highlights

• Susu — Susu is a dynamic and innovative company that offers a wide range of health services for families in the African diaspora. Susu provides a complete offer on Preventive care, Medical treatments, Management of chronic diseases, and Authentic drugs.
• Kasha — Health products and household goods you want, delivered to where you are.
• Zuri Health — .ts-banner-image-1:hover .overlay{background-color:#ffffff} .ts-banner-image-2:hover .overlay{background-color:#ffffff} Popular categories Pharmacy Doctor at home Covid Labs & Diagonstics Wellness Telemed Show all Our Services PharmacyBuy both OTC and prescription medication and have it delivered to your doorstepLabs & DiagnosticsBook labs and Diagnostic tests and get your samples collected from the comfort of your home, hotel

Portfolio highlights

• Jobox — Jobox is a student recruitment platform, built to connect employers, students and graduate career offices. Our focus is to improve graduate employability by ensuring all students have the skills they need to enter, stay in, and progress in the world of work.Jobox’s ecosystem provides employers with access to the best diverse & youthfultalent, students with more employment opportunities and universities with data-driven insights aimed at driving graduate employability forward.
• Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
• Ownedby Technologies — Ownedby is an interactive asset management solution for business and household assets, focused on appliances and devices, giving these unique identity that is traceable online, yet linked to and controlled by owners.

Portfolio highlights

• Prosoma — Prosoma was born out a need to provide more comprehensive care for cancer patients. We have found a fundamental lack of access to psychological care for patients who not only have to face a life-altering disease and treatment, but also crucially have a different set of needs than other psychological patients. Barriers to accessing psychologicalcare often include low numbers of therapists and clinicians in the area, financial or geographical limitations, and the general wellbeing of patients preventing them from attending meetings. All of these issues can be solved by modern technology.By using VR as part of, or when necessary, an alternative to traditional psychological treatment, we can reach patients that would otherwise be left without any support. They can use our tool at home or in the clinics whilst undergoing pharmacological treatment and chemotherapy.We hope to provide patients with a tool that will help them manage stress, cope with the burden of cancer, and eventually improve their quality of life.
• Lifeyear — Digital-first heart care. At scale.
• CareLoop Health — CareLoop, an innovation emerging from the University of Manchester, furnishes patients with digital support resources while simultaneously providing healthcare professionals with the means to monitor and track patient symptoms.