Top 15 Cryptocurrency Startup Investors in South Africa (July 2026)

Portfolio highlights

• MDaaS Global — At MDaaS Global, we build and operate modern, tech-enabled diagnostic centres in clinically-underserved communities, starting in Nigeria. Our big goal is to create affordable healthcare solutions for Africa's next billion.
• Chefaa — Chefaa is a GPS-enabled pharmacy benefits platform connecting patients & pharmacies nation-wide to help patients manage all their pharmacy needs. Chefaa uses big data, data ming & machine learning
• Fulfillment Bridge —

Portfolio highlights

• Ivorypay — Ivorypay is a crypto payment gateway that enables businesses to get paid in stable cryptocurrency and leverage Defi and NFT for growth.Our goal is simply to create a blockchain based payment solution that powers seamless and cheap cross-border transactions in Africa without FX restrictions and also create better spend use cases for theexponentially growing base of crypto adopters on the continent.

Portfolio highlights

• Cuoral — Cuoral is an AI-native platform that helps businesses proactively detect and resolve customer issues before they escalate. We unify support, feedback, and engagement tools into one intelligent layer, transforming reactive customer service into a proactive growth engine. With real-time diagnostics, actionable insights, and automation, Cuoralempowers teams to deliver exceptional experiences at scale.
• BankWise —
• PowerLabs — PowerLabs is an energy and climate technology research and implementation company whose goal is to use intelligent energy to build a world where human output is boundless.

Portfolio highlights

• DEXFIN — DEXFIN operates as a one-stop solution for buying and managing digital assets. The company is based in Prague, Czech Republic.
• AstraKode — Welcome to AstraKode world, here you can discover how easy it can be to create an enterprise blockchain solution with AstraKode Blockchain, our low-code development platform.
• Fungies.io — Fungies is a platform to allow game developers and publishers build their own storefronts. - Allows selling Steam or any games via their own Web Shop - Helps mobile game developers sell in-game items via Web channel - Solves the problem of being locked-up with only distribution via AppStore/PlayStore or Steam: this is an additional saleschannel for all game developers - Web2 and Web3 compatible - We are backed by Outlier Ventures, Tatum and CV Labs, - Team: Founder 10 years building startups, 1 exit, 2 VC-backed companies, CTO built one of the first crypto exchanges in 2017. Worked together for the last 2 years.Reach out if you're looking to invest in Gaming, Blockchain, SaaS

Portfolio highlights

• OnSinch —
• Fether Labs — Fether Labs is a UK-based startup developing wrist-worn XR hand-tracking and haptic hardware. Their technology enables precise gesture control and immersive interaction in extended reality environments, enhancing VR/AR experiences for gaming, training, and digital collaboration.
• Delta Green — Aggregating household assets in large controllable block of flexibility.

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay
• OfferZen — On OfferZen, Dutch tech companies reach out to you with upfront role and salary info so you can make the right career move.
• Real Time Wine — Share your wine moments. Real Time Wine is the social wine discovery app for everyone who enjoys wine, not just those who understand it. [In App Stores NOW!]

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay

Portfolio highlights

• Root — Launch digital and embedded insurance solutions with omni-channel distribution.
• Traction Apps — Traction apps provide businesses end to end tools they need to run and grow their businesses.
• Reliance Health — Reliance Health Global. Improve the lives of your staff with innovative company healthcare benefits fit for any business. You can rely on us.

Portfolio highlights

• Perion — Win Crypto Questing in AAA Games.
• Farmington State Bank — Do more with a Moonstone FDIC insured bank account and manage your non-traditional assets from the same place.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• Coverio — Coverio is a software company that offers enterprise-wide payroll and hiring management software for web4 companies.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!

Portfolio highlights

• Ovex — OVEX is a cryptocurrency exchange company.
• Contents — Contents.com is a tech company that developed an artificial intelligence platform based on a perfect cycle of interaction between data analysis and machine learning systems that makes access to data easier for everyone. Contents.com provides integrated solutions for every online business and customer. Through proprietary algorithm-basedsoftware, Contents.com guarantees specific advanced tools for any needs: all in one unique application platform. The platform provides advanced tools with specific functions: future trends prediction, content generation, user behavior analysis, website performance monitoring, detection of website’s position in search engines, and much more.Contents.com was founded in 2017, currently, the company is present in 4 countries: Italy, Spain, France, and the UK.
• Serenis Health — Serenis is a mental health platform that provides psychotherapy with a strong focus on science & impact measurement

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay
• Investsure — InvestSure is a technology company that uses its software to enable partner investment platforms to sell its unique Investment Indemnity (insurance) product to their clients. InvestSure provides a full set of APIs that trading platform developers can use to integrate the Investure Investment Indemnity product seamlessly and easily into theirwebsites and mobile applications. Once InvestSure technology is added to a trading platform, it enables users to buy insurance on their shares with a single click. The full process from buying to insurance to settling claims is fully automated.The Investment Indemnity product itself is a unique innovation; it is designed to protect to protect shareholders against any losses in share value caused by actual or perceived fraud committed by management. This enables investors to secure their investments. The cost of the product is low enough to not significantly reduce returns of investors where no insurance event occurs, but to provide significant downside protection where an insured event does occur.
• CompariSure — Custom, built-for-purpose service and sales chatbot solutions for financial services providers.

Portfolio highlights

• Upvest — Upvest empowers financial institutions to offer investment products in their app with a modular, scalable, and accessible API. Upvest brings together everything that’s required to offer a broad range of investment products on the website and app. They are connected to the world’s leading asset providers and exchanges to provide the bestinvestments, at the best prices and execution speed.
• Tytan Technologies — TYTAN Technologies builds autonomous interceptors engineered for the realities of modern drone warfare.
• Lookiero Outfittery Group — Check out all the roles at LOOKIERO OUTFITTERY GROUP. Get to know the team, see our offices, learn about our values, and discover the benefits of working at LOOKIERO OUTFITTERY GROUP

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay

Portfolio highlights

• Ivorypay — Ivorypay is a crypto payment gateway that enables businesses to get paid in stable cryptocurrency and leverage Defi and NFT for growth.Our goal is simply to create a blockchain based payment solution that powers seamless and cheap cross-border transactions in Africa without FX restrictions and also create better spend use cases for theexponentially growing base of crypto adopters on the continent.
• SEALCOIN — SEALCOIN is a unique cryptotoken designed for Internet of Things (IoT) and Machine-to-Machine (M2M) communication.
• AgNext — AgNext builds trusted food chains with 5M+ tonnes of assured food, serving 2,000+ locations globally with 25+ leading brands.