Top 25 Cryptocurrency Startup Investors in South Africa (September 2026)

Portfolio highlights

• 3Commas — 3Commas develops a crypto-asset management tool for tracking investments and exchanges in a unified platform. It provides access to a unified dashboard as the central hub for trading and portfolio management execution.
• Fuel Labs — At Fuel, we are building the fastest execution layer for the modular blockchain stack.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• MDaaS Global — At MDaaS Global, we build and operate modern, tech-enabled diagnostic centres in clinically-underserved communities, starting in Nigeria. Our big goal is to create affordable healthcare solutions for Africa's next billion.
• Chefaa — Chefaa is a GPS-enabled pharmacy benefits platform connecting patients & pharmacies nation-wide to help patients manage all their pharmacy needs. Chefaa uses big data, data ming & machine learning
• Waspito — We are the platform that engages Africa into the conversation and action to drive affordable and accessible quality healthcare across the continent.

Portfolio highlights

• Will Media — founder @will_ita Former @airbnb and @lime policy guy. Now fighting for the good cause of knowledge in democracy
• Contents — Create, localize and govern content at scale with an enterprise AI platform and digital agency for copy, blogs, SEO, translations, images, video and campaigns.
• Serenis Health — Serenis Health provides video-based psychotherapy, coaching, and psychological support courses. It believes that the internet is critical to increasing access to mental health care. It makes use of data and digital tools to improve the efficacy of therapies. But, unlike other platforms, it is also a medical center, which means it is responsible forcourse quality and must meet the same standards as any polyclinic.

Portfolio highlights

• Ivorypay — Ivorypay is a crypto payment gateway that enables businesses to get paid in stable cryptocurrency and leverage Defi and NFT for growth.Our goal is simply to create a blockchain based payment solution that powers seamless and cheap cross-border transactions in Africa without FX restrictions and also create better spend use cases for theexponentially growing base of crypto adopters on the continent.

Portfolio highlights

• Ivorypay — Ivorypay is a crypto payment gateway that enables businesses to get paid in stable cryptocurrency and leverage Defi and NFT for growth.Our goal is simply to create a blockchain based payment solution that powers seamless and cheap cross-border transactions in Africa without FX restrictions and also create better spend use cases for theexponentially growing base of crypto adopters on the continent.

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay

Portfolio highlights

• BFree — BFree focuses its collection processes on sustainably leading customers out of debt by giving them back control over their finances.
• FireID — FireID is a venture builder that helps makers, with unique skills and passion, build businesses to solve meaningful problems.
• Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.

Portfolio highlights

• Upvest — Upvest is a financial technology company that provides an investment infrastructure platform enabling other businesses to offer investment products through a single API. The firm’s core product is a modular investment API that handles complex backend functions such as brokerage, settlement, custody, and compliance, allowing fintech platforms,banks, and wealth managers to embed investing features into their apps and services. This infrastructure supports a range of asset classes, including stocks, exchange‑traded funds, mutual funds, and digital assets, and can be configured to enable fractional investing, savings plans, and automated investment experiences. Upvest’s platform manages the technical and regulatory aspects of investment operations, so its clients can focus on user experience and product innovation without building extensive financial infrastructure themselves. Its solutions encompass account management, real‑time transaction processing, and portfolio services that integrate with existing digital offerings.
• Tytan Technologies — TYTAN Technologies builds autonomous interceptors engineered for the realities of modern drone warfare.
• Lookiero Outfittery Group — Check out all the roles at LOOKIERO OUTFITTERY GROUP. Get to know the team, see our offices, learn about our values, and discover the benefits of working at LOOKIERO OUTFITTERY GROUP

Portfolio highlights

• Ivorypay — Ivorypay is a crypto payment gateway that enables businesses to get paid in stable cryptocurrency and leverage Defi and NFT for growth.Our goal is simply to create a blockchain based payment solution that powers seamless and cheap cross-border transactions in Africa without FX restrictions and also create better spend use cases for theexponentially growing base of crypto adopters on the continent.
• SEALCOIN — SEALCOIN is a unique cryptotoken designed for Internet of Things (IoT) and Machine-to-Machine (M2M) communication.
• AgNext — AgNext builds trusted food chains with 5M+ tonnes of assured food, serving 2,000+ locations globally with 25+ leading brands.

Portfolio highlights

• Clerq — Clerq makes it easy for your business to accept low-cost, guaranteed bank payments with the ease and safety of cards.
• RobCo — Easily automate the repetitive tasks in your production facility with modular industrial robots from RobCo.
• Senra Systems — Senra Systems operates in the manufacturing industry, focusing on software configuration to improve manufacturing processes. The company works to transform skilled assembly tasks into production lines, enhancing production efficiency. It also has involvement in the Aerospace and Defense industry. It collects anonymous data through Google Analyticsto analyze user behavior and use the insights to improve its services.

Portfolio highlights

• Momint — Momint is the Web3 investment platform of the future. The safest and easiest to use NFT marketplace in the world. Discover the real-world potential of NFTs.
• Rabbit — At Rabbit, we plan to change how the world shops.Retail has witnessed one revolution before with the introduction of E-Commerce that changed how customers order stuff and the second revolution is here! We are proud to be among the pioneers, a handful of global entrepreneurs that are leading and shaping the retail's second revolutionWe arefunded by amazing VCs that are helping us build the next big thingYou feel it is vague? that's intended as we are still building in stealth. but trust us, it is COOL!
• Beeline Learn — Enjoy Learning Effectively. Beta version is now LIVE!

Portfolio highlights

• Cuoral — Proactive customer success and engagement. We help you reduce customer churn and increase retention and revenue.
• BankWise — Liga123 merupakan situs slot jackpot 888 slots paling gacor dan juga platform ini terdata paling banyak dicari hari ini karena memiliki akses yang mudah tanpa harus menggunakan Apk tambahan seperti VPN untuk memainkan game favorit.
• PowerLabs — PowerLabs is an energy and climate technology research and implementation company whose goal is to use intelligent energy to build a world where human output is boundless.

Portfolio highlights

• OnePipe — OnePipe aggregates APIs from banks and fintechs into a standardized gateway that is easy to integrate and makes partnerships seamless.
• Momint — Momint is the Web3 investment platform of the future. The safest and easiest to use NFT marketplace in the world. Discover the real-world potential of NFTs.

Portfolio highlights

• Elimutab — Elimutab - Find the best learning tablets for children and students, including options for 1-year-olds, studying with pens, and work and study needs.
• OX Delivers — Our objective is to deliver affordable transport in emerging markets, creating a self-reinforcing cycle of economic growth and social impact. To achieve this, we are developing the world's first clean-transport ecosystem that combines goods shipment with financial, trading & marketing services. This OX ecosystem will be enabled by ourunique zero-emissions OX truck; the only purpose-designed electric vehicle for emerging markets.
• Rabbit — Transforming transportion in the region. Rabbit is a micro-mobility sharing platform for short-distance transportation using environmentally friendly vehicles.

Portfolio highlights

• DEXFIN — DEXFIN operates as a one-stop solution for buying and managing digital assets. The company is based in Prague, Czech Republic.
• AstraKode — Welcome to AstraKode world, here you can discover how easy it can be to create an enterprise blockchain solution with AstraKode Blockchain, our low-code development platform.
• Fungies.io — Merchant of Record for SaaS, games, and digital products. Fungies handles global payments, VAT and sales tax, and checkout. Free to start, commission only.

Portfolio highlights

• Shiplong — Shiplog gives every customer a live profile and decides the next best action in real time, so you expand, retain and grow revenue from the customers you already have.
• Fether Labs — Fether labs is pioneering new sensors for monitoring tendon dynamics at the wrist, enabling the seamless translation of human movement into digital output.
• Delta Green — Aggregating household assets in large controllable block of flexibility.

Portfolio highlights

• OMA Mind — Connect with qualified mental health practitioners, ready and available round the clock.
• Momint — Momint is the Web3 investment platform of the future. The safest and easiest to use NFT marketplace in the world. Discover the real-world potential of NFTs.
• NeuralGarage — VisualDub brings cinematic-grade AI lip-sync and visual dubbing to film studios, OTT platforms, and advertisers worldwide.

Portfolio highlights

• Ask Gogo — Ask Gogo develops data free application designed to facilitate buying, selling, renting, and job searching without using mobile data.
• DigiSquad — DigiSquad is a team of entrepreneurs in the payments industry striving to expand the reach of digital payment platforms in underserved regions.
• AKELO Group — AKELO Group provides a marketplace for embedded financial services and solutions for corporates, retailers and SME merchants.

Portfolio highlights

• Lua — Build, deploy, and scale enterprise-grade AI agents. Ship your first agent without touching infrastructure.
• Salus Cloud — Empowering developers worldwide with seamless and secure application deployment and management. Join the revolution. #Salus_Cloud
• Traction Apps — Traction apps provide businesses end to end tools they need to run and grow their businesses.

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay
• FlexClub — FlexClub allows merchants to easily collect recurring payments by providing a more inclusive billing solution, innovative risk protection, and seamless customizable onboarding.

Portfolio highlights

• Laylo — Laylo is a boxed wine brand.
• Badili — Badili is a one-stop shop for buying and selling used and refurbished phones. Founded in 2021 and is based in Nairobi.
• Incredible — Pay off credit cards faster, reduce your interest payments and reclaim your financial freedom.

Portfolio highlights

• Tapaya — A modern, fast payment app that runs on any device you already own: phone, tablet or kiosk. Accept contactless payments in store with Tap to Pay, with nothing to buy and nothing to install on a counter.
• ArcSpace — ArcSpace is a SpaceTech company that develops proprietary high energy electron beam technology to cut, join, and weld materials under vacuum conditions. This compact system enables the maintenance, infrastructure assembly, and in-orbit repair of satellites that were not originally designed for servicing.
• WanderWallet — Pay with Pix in Brazil, Mercado Pago in Argentina, QR in Bolivia, without a local bank account. Fund with USD or EUR, scan QR codes, pay instantly. No ATM fees.

Portfolio highlights

• WizCommerce — AI for Modernizing Wholesale Sales & Ops.
• Cellarim Labs — Cellarim is at the forefront of the biomanufacturing revolution. As a pioneer in the biotechnology business, we specialize in producing high-value biomolecules in a sustainable manner using our cutting-edge platform. Our objective is to revolutionize the landscape of biomanufacturing by providing greener, more efficient, and scalable solutions, andwe've dedicated ourselves to redefining industry standards, ensuring that our methods are as environmentally friendly as they are effective.
• Agnikul — Agnikul Cosmos designs and manufactures orbital-class launch vehicles powered by 3D-printed engines. From custom payloads to affordable private launches, we make space access simple, scalable, and mission-focused.

Portfolio highlights

• VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay
• OfferZen — On OfferZen, Dutch tech companies reach out to you with upfront role and salary info so you can make the right career move.
• Real Time Wine — Share your wine moments. Real Time Wine is the social wine discovery app for everyone who enjoys wine, not just those who understand it. [In App Stores NOW!]

Portfolio highlights

• Rilla — Demonstrating 90% reduction in cost-to-serve for live-streaming, Rilla is rewiring the content economy, directing the value generated back to creators and their communities.By leveraging audience bandwidth and rewarding them with ownership in the network, the savings are equivalent to a free month subscription every year for a moderate level ofviewership.Founded by the technical founders behind Altered State Machine, acquired for 214m. Together for 5+ ventures, collectively raising 130m+ and valued at 1b+.
• Osmo — Osmo is a payment company that helps people to send and receive money immediately.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!