Top 15 Biotech Startup Investors in South Africa (July 2026)

Portfolio highlights

• Matta — Matta delivers artificial intelligence software and services for businesses. Offerings include custom model development, data preparation, and API-based deployment across computer vision and language tasks. Tooling covers experiment tracking, evaluation, monitoring, and scalability to move prototypes into production. Services also addressintegration with existing data pipelines, security considerations, and MLOps practices. Engagements include solution design, implementation, and knowledge transfer so internal teams can operate and iterate models over time.
• Willo — Willo is advancing and scaling true wireless power for humanity, technology, and industry. Discover the company powering the next era of energy delivery.
• Tangible — Tangible empowers hardware companies with sustainable asset-based lending solutions. Our platform streamlines debt funding, compliance automation, and financial product design, enabling efficient capital mobilization and comprehensive reporting for a greener future. Scale your business with Twist.

Portfolio highlights

• Novel Farms — Novel Farms uses microbial fermentation to develop cruelty-free, inexpensive and tunable bioscaffolds for the production of cell-based meat products. Novel Farms mission is to craft the taste and texture of the gourmet meats and transform cell-based meat consumption into a sought-after culinary experience for the next generation of consciouseaters.
• Minus — A sustainable coffee alternative, combining the taste, look, and smell of coffee with a smaller footprint to ensure a brighter future for coffee and the planet.
• Unicorn Biotechnologies — Unicorn Biotechnologies is developing a fully automated manufacturing platform to enable cellular agriculture producers to seamlessly scale products from the lab bench to supermarket shelves. Our full stack platform combines hardware, software and analytics to completely automate cellular agriculture manufacturing, reducing costs and increasingproduct quality. By providing a clear path to scale cellular agriculture from grams to tons, we will improve human and planetary health and drive the transition to animal free agriculture.

Portfolio highlights

• MariHealth Solutions (RF) (PTY) LTD — Proteomics-powered analytics for aquaculture. We quantify 3,000+ proteins per sample to deliver deep biological insights for fish health, nutrition, and farming.

Portfolio highlights

• Phyenti —
• Immobazyme —
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• CubeSpace — Industry-leading modular attitude determination and control (ADCS) products and solutions. Laser-focused on our customers' success. Your global ADCS partner.
• SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• SwiftVee — SwiftVEE is a livestock trading mobile app. They support live webcast livestock auctions and silent auctions. Their platform facilitates the discovery and viewing of livestock auctions.They provide webcast advertising, online auctions, and online livestock insurance services and data products for financial institutions.
• Tanda — As a Tanda Agent, you can sell Kenya's favorite digital products, and grow your duka while you're at it
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• PatientPartner — Discover PatientPartner, the leading patient engagement software transforming pharma and med-tech with scalable, data-driven solutions that drive better health outcomes.
• Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling
• SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.

Portfolio highlights

• Hive Health — Hive Health is a digital platform that provides access to easy-to-use, affordable, and quality HMO plans for SMEs in the Philippines.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.
• Netbank — Netbank provides various banking solutions like alternative lenders, payment solutions, neobanks, and wallets.

Portfolio highlights

• Opalia — Opalia is introducing a new era of dairy: functional, delicious, and sustainable dairy made from mammary cells.
• Hooked Foods — Leading the transition to a harmless seafood system by serving healthy vegan seafood for everybody to truly enjoy.
• Cultimate Foods — At Cultimate, we are transforming the flavor and aroma industry with natural innovative ingredients.

Portfolio highlights

• CMO —
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
• Conservio — Discover and Book South Africa's best nature accommodations with Conservio. Book vetted accommodations, easy and safe to book online.

Portfolio highlights

• Vycarb — Vycarb is a Brooklyn-based firm that enables decentralized carbon removal through real-time, autonomous, and direct detection of CO2 in water.
• Plasmaleap —
• Hachiko —

Portfolio highlights

• Yamify — Yamify is an AI platform where intelligent agents reliably run mission-critical business workflows in Africa. Founded by Silicon Valley engineers, our platform automates complex operations by integrating humans, systems, and infrastructure reliably, even under connectivity, latency, and compliance challenges. Starting with on-prem deployments,Yamify is evolving into a full AI automation infrastructure for African enterprises.
• Shopstar — A place for makers and creators to start, manage and grow successful online stores. Our built-in design, payment and shipping methods provide you with an all in one solution. Get started with a free 14-day trial.
• Kashat — The region's first nano financial service provider, offering small productive loans, and serving as the entry point to financial inclusion for the un- and underbanked population in Egypt.

Portfolio highlights

• Propel Foods — Startup that creates plant-based and hybrid protein through technology.
• Peruvian Veef — Peruvian Veef is an offline and online store that offers real burgers, grilled seitan, crispy cravings, and vegan nugget products.
• High Time Foods — High Time Foods provides shelf-stable and moldable plant-based meat alternatives to foodservice operators. Their first product is a plant-based chicken alternative that does not require refrigeration. The product is moldable and can be used in any cuisine as a substitute for chicken.

Portfolio highlights

• SettleKit — We help newcomers to the US set up their life here
• De Novo Foodlabs — Producing non-animal dairy proteins using precision fermentation
• Smart Separations — Smart Separations is a limited company based in London UK that has patented an innovative microfiltration technology to produce ceramic filters with self-assembled controllable pores of uniform size in the range between <1 and 50µm. This tight pore size control and range availability will revolutionise the field of MF with a cost-effectiveproduct.It aims to be the world’s leader in MF and particle separations technology – filling the void gap that exists in the market nowadays.

Portfolio highlights

• Circulaire — Premium second hand price comparison site. We collect retailers so that consumers can save time and money.
• Nordic Angels — Join Nordic Angels, the largest investor network in the Nordics, to collaborate, connect, and strengthen the startup ecosystem through exclusive events and resources.
• Transparent — Transparent offers speakers with a modular design that can be repaired and upgraded over time. The company was founded in 2014 and is based in Stockholm, Sweden.