Top 50 Manufacturing Startup Investors in United States (June 2026)

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Humio — Humio operates as a time-series logging and aggregation platform designed for unrestricted and comprehensive event analysis. It is deployable on any infrastructure including both in the cloud and on-premises. Humio enables data aggregation, exploration, reporting, and analysis from a range of sources ingesting massive volumes of log data instantly.Its data storage and in-memory search/query engine technologies provide customers cost-competitive log management and analysis solution, all while requiring significantly less hardware and engineering resources.The company was founded in 2016 and is headquartered in London, England.
• OpusClip — Opus Clip turns long videos into high-quality viral clips for you to share on TikTok, YouTube Shorts, and Reels to increase social media reach.
• Arda Therapeutics — Arda Therapeutics is a biotechnology company taking aim at chronic diseases and aging by eliminating the pathogenic cells that drive these conditions. Their approach starts by using single-cell data to identify pathogenic cells and specific markers to target them. They then design therapies to eliminate these - and only these - cells.Arda wasfounded in 2021 in the San Francisco Bay Area, CA.

Portfolio highlights

• Arraiy — Headquartered in Palo Alto, Arraiy is building the premier AI-driven production platform for the motion picture and television industry. Arraiy is collaborating with major studios, industry veterans, and award-winning artists to re-invent the filmmaking process with machine learning at its foundation. With its products, Arraiy seeks to enhance thecreative freedom of storytellers and unlock the next generation of visual storytelling.
• Clarifai — Clarifai is the leading Machine Learning, Computer Vision, NLP Platform. Label, train, deploy models on one AI platform for developers & data scientists.
• Primer — Primer makes powerful mission-ready AI software designed to work in your environment, on your data. We help national security teams sift through massive unstructured data sets to find the needle in the haystack, understand and visualize their data, and act collaboratively. Our mission is to empower decisions that can be defended, and acted upon confidently.

Portfolio highlights

• Hunch — Hunch is a consumer web application that is building the "taste graph" of the internet, mapping every person on the internet to every entity on the internet and their affinity for that entity. An entity could be a web site, a cookbook, a hotel room, a celebrity, a restaurant, etc.Hunch creates a taste profile by asking them a seriesof questions which range from serious to profound and subsequently can make recommendations personalized to that user, which live in "topics".Topics vary widely, from entertaining subjects like 'Which superhero would you be' to more conventional questions like 'Should I Switch to A Mac?' The system then uses the answers to these questions to offer the user a suggested solution, a "hunch" of what the user would like.
• Speak — People spend $90 billion a year on human english teachers that are expensive and ineffective. Speak offers a mobile app where you can have english conversations with your phone about real world scenarios like interviewing for a job or asking for directions. It uses speech recognition to identify english words through thick accents and teach peopleto speak more clearly. Meanwhile, it’s building a massive database of accented-english speech, which can be used to improve its system and other speech recognition systems. Speak’s team formerly built accent detection systems and sold Flashcards+ to Chegg. Though AI translation might reduce the need for people to know other languages, speaking English remains a valuable skill people are willing to pay for.
• The Climate Corporation (Bayer Crop Science) — The Climate Corporation (formerly WeatherBill) aims to help farmers around the world protect and improve their farming operations with uniquely powerful software, hardware and insurance products. The company’s proprietary Climate Technology Platform combines hyper-local weather monitoring, agronomic modeling, and high-resolution weather simulationsto deliver Climate Basic and Climate Pro, mobile SaaS solutions that helps farmers improve profitability by making better informed operating and financing decisions.

Portfolio highlights

• Citrea — Bitcoin's First ZK Rollup
• Polymarket — Bet on your beliefs
• Workstream — Workstream is an automated hiring platform that helps companies employing hourly workers. The platform helped Jamba, Chick-fil-A, McDonald's, Dunkin', Applebee's, Auntie Anne's, Cinnabon to increase their bottom line and cost savings.Workstream was founded in 2017 and is headquartered in San Francisco, California, UnitedStates.

Portfolio highlights

• Haiqu — Default page description
• Orbital Industries — Orbital Materials leverages AI to design and deploy advanced materials & climate technologies for the long-term habitability of our planet.
• Avalanche Energy — Avalanche Energy operates as a fusion energy start-up.

Portfolio highlights

• HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
• Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.
• Soiltech Wireless — Soiltech Wireless is a developer of ag-tech solutions to design electronic devices for agricultural professionals. Its product provides real-time data to drive efficiency and optimize quality. It also provides actionable data without installation hassles and creates scalable monitoring solutions for farmers.The company was founded in 2019 and isheadquartered in Rupert, Idaho.

Portfolio highlights

• Chord — Chord is a commerce data platform purpose-built for modern brands. Chord enables brands to unify, synthesize, and orchestrate their data to drive radical decisions and revenue.
• Jitsu — An expedited urban last-mile delivery service leveraging purpose-built technology and a gig driver fleet to catalyze client brand growth.
• Nucleus RadioPharma — Founded by Eclipse Ventures and Mayo Clinic, Nucleus RadioPharma is a new company built to ensure cancer patients can access potentially life-saving radiopharmaceuticals by developing technologies to modernize the clinical development, manufacturing, and supply chain of these promising new treatment tools.

Portfolio highlights

• SunDensity — SunDensity has developed a groundbreaking Photonic Smart Coating (PSC™) technology that enables the up and down conversion of the wavelengths in white light (UV to IR) to match the desired band which can solve several in-efficiencies in photonics. By conversion of spectrum, they have developed, and field tested a patent-pending PSC™ thatsignificantly reduces the cost of electricity generated by solar photovoltaics (PV) applications, customizes thermal and optical behavior of architectural glass, and increases the quantum efficiency of optoelectronic instruments.
• Ndustrial — Ndustrial delivers a real-time industrial intelligence platform that enables companies to gain new levels of insight into their business processes and energy intensity and then optimize and transform them for sustained competitive advantage.
• Leading Edge Equipment Technologies — Leading Edge Crystal Technologies is a developer of kerfless, single crystal silicon wafers intended to be used in solar panels with higher efficiency and lower cost that fit into existing module manufacturing processes without any changes.

Portfolio highlights

• WeaveGrid — WeaveGrid operates with utilities and owners of electric vehicles (EV) to allow and speed up transportation electrification. Using machine learning, optimization, and predictive analytics, the company's software solution solves several EV-grid integration challenges for utilities in a systems-oriented manner; helps integrate renewable energyresources on the grid; and saves utility customers' money on their bills.
• 75F — 75F's award-winning smart sensors and controls improve indoor air quality and make commercial buildings more comfortable and energy efficient. Automatically.
• Dandelion Energy — Dandelion's nation-leading geothermal drilling and heat pumps provide cost-effective, renewable home heating and cooling.

Portfolio highlights

• Farcast — Unlocking satellite internet capacity through user terminal innovation
• Solugen — Solugen's mission is to decarbonize the chemicals industry. Solugen combines synthetic biology with metal catalysis to make carbon negative chemicals at scale.Solugen's patented approach takes advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products cost-competitive with thecompetition.
• Valence Discovery — Empowering drug discovery scientists with the latest advances in AI-enabled drug design

Portfolio highlights

• ITeam — iTeam is transforming the way information technology (IT) and audio/video (A/V) installation services are packaged, sold and delivered through a new approach called Service-as-a-Product™ (SaaP™).
• Monster Mosquito — Monster Mosquito focuses on providing all-natural mosquito sentry repellent systems for its clients. The company also develops a biodegradable compound insecticide to exterminate biting insects.Monster Mosquito uses mosquito mist systems, which contains pyrethrum, a natural mosquito killer made from chrysanthemums. The company was founded in 2002by Kemper Modlin and Leo Niekerk.It is based in Spring, Texas.
• Davidson Instruments — Davidson has designed and developed innovative temperature-tolerant pressure measurement instrumentation that is rugged, immune to electromagnetic interference, and intrinsically-safe based on patented fiber optic sensing technology. The instrumentation has been proven through numerous installations with over one million hours of time inservice. Davidson's products include instruments for making high resolution static pressure measurements and others for making high speed dynamic pressure measurements.

Portfolio highlights

• Haiqu — Default page description
• Step — Build credit, bank smarter, and grow your money with Step. No hidden fees, no minimums. Join 7M+ users taking control of their finances. Start free today.
• Switchboard — Switchboard's service design, coaching, and software offerings generate real results for higher ed teams and institutions.

Portfolio highlights

• Epirus — Epirus is a high-growth technology company that develops cutting-edge directed energy systems and power management solutions to transform multiple industries.
• Operant — Own OperantAi.com today. Secure checkout and guided transfer support. No hidden fees.
• Quadient Accounts Receivable by YayPay — YayPay accounts receivable automation software helps businesses collect faster, forecast cash flow accurately, and improve payment process. Automate your AR

Portfolio highlights

• Scalvy — Scalvy is a distributed power delivery company that develops modular power electronics and energy systems that enable distributed power delivery for applications such as data centers, energy storage, and electric mobility. The company replaces traditional centralized power architectures with a distributed system of “power neurons,” which convertand manage electricity closer to the point of use, improving efficiency, scalability, and system reliability. Its platform is built on software-defined, modular components that can be scaled across different power levels and use cases, allowing flexible deployment in high-demand environments. These systems support high-voltage output ranges and deliver high power density while reducing the physical footprint and complexity of conventional power infrastructure.
• Carbo Culture — We are a project developer with proprietary climate technology. We are building a rapidly scalable biochar carbon removal solution.
• Critical Loop — Critical Loop is an energy technology company that provides on-demand power solutions for industrial and infrastructure applications by combining modular hardware and software systems. Its platform integrates behind-the-meter battery storage, on-site generation, and grid power through intelligent controls that dynamically manage energy supply basedon availability and demand. The company develops and deploys scalable microgrid systems, including relocatable batteries and control units, which can be implemented rapidly to address delays or limitations in traditional grid capacity. It also handles project development, system design, deployment, and ongoing operations and maintenance, enabling continuous monitoring and optimization of power performance. Critical Loop’s solutions are used across sectors such as manufacturing, transportation, data centers, and critical infrastructure to ensure consistent and flexible energy access.

Portfolio highlights

• NS1 — NS1 makes it easy to use next-generation DNS for advanced traffic routing, automation & application resiliency. Optimize your websites, apps & infrastructure.
• DNK — Dongnae provides an online real estate platform that digitizes the rental and home-buying market. The company's platform assists users to find the right house based on their needs and purpose, even find easy transport to work from the resident with the assistance of the brokers, enabling users to save time and energy on finding the right placeto stay in.It was founded in 2020 and is headquartered in Seoul, South Korea.
• Finkargo — FINKARGO created Latin America’s first supply chain platform for micro, small and medium enterprises empowering them with centralized control, shipment tracking, analytics and embedded financing for all of their international commerce operations. With its solution, Finkargo will enable international trade for Latam’s 27.5 million MSMEs.

Portfolio highlights

• Julep — We are Julep, creators of innovative makeup, skincare, nail polish & sets. Every day is a chance to Brave Pretty.
• Shapeways — Shapeways is the #1 online 3D printing service company. Working with over a million customers since 2007 - Get 3D products and parts delivered to over 100 countries.
• Adaptive Security — Adaptive's next-generation security training and simulations protect businesses from deepfakes, generative AI phishing, SMS attacks, voice phishing, and more emerging threats.

Portfolio highlights

• KupiVIP — KupiVIP is a Russian online fashion retailer selling discounted fashion and home goods from high-street and luxury brands. It has grown rapidly to become a household name in Russia, with 6 million customers. The online fashion retailer hosts up to 20 private online flash sales every day.KupiVIP was launched in 2008 by Vladimir Kholyaznikov,Mikhail Konoplev, and Oskar Hartmann. It is based in Moscow, Russia.
• OXOS Medical — Micro C develops and markets innovative medical imaging devices ergonomically designed for surgeons and physicians. Micro C delivers increased clarity, reduced radiation exposure, faster workflow, and increased surgical and clinical productivity. It is designed for treating extremities in both surgical and clinical environments. Its initialproduct, the Micro C hand-held, multi-modal x-ray, and digital imaging device enables doctors to capture images with greater accuracy, clarity, safety, and speed. This information concerns a use that has not been approved or cleared by the Food and Drug Administration.The company was founded in 2016 and is a U.S.-based company that was founded by Dr. Greg Kolovich and Evan Ruff.
• Polystream — Polystream is completely rethinking and realising new ways of how to use the visual cloud, from server to client, from network to edge as we build the 3D Internet. Powered by our breakthrough command streaming technology, you can now instantly engage, grow, and monetise audiences of all shapes and sizes wherever they are in the world; whether it’splayers, streamers, or viewers. Our synchronous spectator engine Fantom enables cloud native games and experiences to be cost-effectively streamed with unrivalled reach, and unprecedented scale.

Portfolio highlights

• Scindo — Creating a novel biological process to turn low-value plastic landfill waste into high-value molecules.
• Parting Pro — Funeral home software dedicated to creating the best death care experience. Grow your business with online arrangements and digital case management.
• Orbit Fab — Orbit Fab is creating the future of on-orbit satellite refueling. We maximize your operational assets by enabling mission flexibility and freedom of action in space.

Portfolio highlights

• AviadoBio — AviadoBio mission is to transform the lives of people living with neurodegenerative disorders by developing and delivering transformative gene therapies for diseases including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The Company’s technology is based on pioneering research from King’s College London and the UK DementiaResearch Institute.
• Sagimet Biosciences — Sagimet Biosciences better reflects our expertise in fatty acid metabolism and current focus on developing ground-breaking therapeutics to treat the liver disease NASH.
• Tarveda Therapeutics — Developing Pentarins to make a difference in the treatment of patients with solid tumor malignancies

Portfolio highlights

• Amca — Amca acquires and develops critical aerospace and defense products and then scales them to deliver what the industry needs next. The company emphasizes rapid prototyping and delivery of new products, aiming to respond promptly to customer needs. Amca is committed to deploying top engineering and manufacturing talent to assist customers in buildingnew products and solving complex problems.
• Orbit Fab — Orbit Fab is creating the future of on-orbit satellite refueling. We maximize your operational assets by enabling mission flexibility and freedom of action in space.
• Base Power — Base provides a battery-powered home energy service so you can enjoy power without interruption and save money. Now available in select regions of Texas.

Portfolio highlights

• Universe — Universe is the first website builder and commerce platform built for mobile devices. With its magical drag and drop interface, anyone can easily create a website and start selling online in minutes from anywhere.
• David Energy — David Energy is an electricity provider that designs, builds, and manages onsite energy grids. The company empowers buildings with the tools needed to maximize onsite energy and bring transparency to a traditionally opaque, commoditized industry. It provides hands-on expertise and on the ground support, all delivered through its software platform.Founded in 2017, David Energy is headquartered in Brooklyn, New York.
• Gradient — Gradient Security Mesh. Prevents breaches before they happen by securing what others can't. Cybersecurity that goes beyond zero trust.

Portfolio highlights

• Umecc — Umecc offers a line of metallurgical equipment, spare parts, and refractories. The company operates a large variety of manufacturing facilities locally as part of its manufacturing group. Their products and services are provided individually or as a comprehensive package, including all engineering services.
• Cloverleaf.me — Cloverleaf helps build great work teams and improve employee engagement using assessments like Enneagram, DISC and 16-Types to identify team strengths and coach work teams to work better together.
• Whitman Controls — Whitman Controls specializes in the manufacture of miniature pressure, vacuum, temperature, and liquid level switches and sensors.

Portfolio highlights

• ESAI — ESAI is the viral storytelling platform for Gen Z college applicants and young professionals.
• Yendo — Our mission is to provide everyone with the most accessible, most affordable, and most transparent credit by leveraging their vehicles.
• Polygon — Polygon is the most proven way to build and scale your decentralized application and projects on Ethereum, the world's largest blockchain ecosystem.

Portfolio highlights

• HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
• TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
• Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Portfolio highlights

• Vital Lyfe — Vital Lyfe is a Climatech product manufacturer that develops systems to produce safe drinking water from a range of natural sources, including seawater, without reliance on centralized infrastructure. The company designs portable water-making hardware that combines filtration, purification, and engineering principles adapted from aerospace toenable autonomous operation in diverse environments. Its offerings aim to serve use cases where traditional water infrastructure is limited or unavailable, such as humanitarian relief, maritime operations, disaster response, and off-grid communities.Vital Lyfe provides hardware platforms alongside supporting software for monitoring and management of water quality and system performance. The company engages with partners in sectors like non-governmental organizations, maritime organizations, and outdoor or expedition users to deploy and validate its solutions. It continues to refine and scale its technologies toward broader market availability and expanded field applications.
• Castelion — We are a modern defense production company building the next generation of military hypersonic, vehicle, and strike systems to deter future wars.
• Heaviside Industries — Heaviside Industries is a defense technology company that develops autonomous precision munitions for land, air, and sea systems.

Portfolio highlights

• GridStrong —
• Lydian — Lydian aims to accelerate the decarbonization of the chemical industry by electrifying the chemical production process. Founded in 2021 by Branko Zugic, Lydian is headquartered in
• Parallel Systems — Parallel Systems designs an autonomous, zero-emissions freight transportation system. The company believes the future of freight transportation should be fast, inexpensive, and clean, while also reducing congestion on the highways. Parallel Systems was founded in 2020 and is headquartered in Los Angeles, California.

Portfolio highlights

• HelpNow — HelpNow Corporate Site
• Patlytics — Patent discovery, analytics, comparison, and workflow. Simplified via Artificial Intelligence.
• Tako — Tako is a deep research platform that turns data into insightful analysis, chats and reports.

Portfolio highlights

• MightyFly — MightyFly is enabling worldwide access to goods with fast, on-demand delivery services for businesses and consumers. We’re putting the infrastructure in place to connect remote locations together with long range, heavy cargo aircraft. Many areas in the world today suffer from an inability to obtain critical and often urgently needed goods andsupplies at an affordable cost. Our goal at MightyFly is to solve this problem through express, customized aerial drone delivery services. MightyFly drones will transport cargo to multiple locations in a single flight across hundreds of miles of remote terrain that is difficult if not impossible to cross with trucks or other ground vehicles. We are developing vertical-takeoff-and-landing (VTOL) drones that fly more than 300 miles, and carry payloads in excess of 50 pounds at a fraction of the cost of helicopters. Featuring automated cargo loading and unloading, and requiring no launch or recovery infrastructure, MightyFly drones will accommodate ad-hoc deliveries to undeveloped sites as well as servicing locations along established routes.
• Gradescope — Grade your existing paper-based assignments in half the time and see exactly what your students learned, for free.
• Autolane — Autolane creates the operating system for curbside autonomy, which uses cutting-edge hardware and SaaS infrastructure to authenticate, park, load, and dispatch ride-hail and delivery trucks without the need for human interaction.

Portfolio highlights

• Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
• SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
• Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Portfolio highlights

• Synvivia — Synvivia makes ON-OFF switches for genetically engineered organisms. These protein switches are controlled by small molecules. By installing these switches into an organism, Synvivia creates engineered organisms that can be controlled with small molecules.
• PlanetWatchers — Highly accurate crop growth, wind, hail and flood damage assessments at scale. Supporting the crop insurance industry with acreage and claims validation.
• Sepion Technologies — Sepion is an advanced membrane company offering a platform suite of highly-tunable nanoscale membranes for multiple industrial markets. The company was founded in 2015 and is based in Emeryville, California, United States.

Portfolio highlights

• RobCo — Easily automate the repetitive tasks in your production facility with modular industrial robots from RobCo.
• Rillet — Rillet automates majority of month-end close and offers powerful GAAP and SaaS reporting. The software has built-in revenue recognition, invoicing, and AI-powered accounting.
• Nevis — Nevis is the world's first AI-powered platform designed specifically for wealth management. It automates operational tasks that consume as much as 80% of a financial advisor's day, such as meeting preparation, document management, opening custodian accounts, and client onboarding. This allows advisors to focus more on deliveringpersonalized client service and growing their businesses.

Portfolio highlights

• Axoft — Redefining health with unparalleled access to neural code.
• Sync Computing — From granular reports and cost allocation to optimizations, Slingshot has the tools to help you maximize your investment. Request your personalized demo today.
• RISE Robotics — THE HUMAN EMPOWERING ROBOTICS COMPANYRise Robotics designs, makes and sells breakthrough mechanical products.The company was founded in 2011 to advance the robotics industry with the ultimate goal of enabling powerful wearable ExoSUITS™ for all.Our first product Bacon Robotic Air Compressor™ disrupts handheld air compressors.Theinnovation that enabled the Bacon Robotic air compressor™ is the Cyclone Linear Drive. A new mobile robotic component that can advance many applications. Cyclone drives enable piston or muscle like actuation. It was inspired by our ExoSuit™ explorations.

Portfolio highlights

• Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
• Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
• Hippocratic AI — The First Safety Focused LLM for Healthcare

Portfolio highlights

• Cohley — Cohley is a content marketing platform focusing on user generated content, visual asset creation, and text review generation. Streamline your content generation today!
• Shipsi — Shipsi empowers any retailer with the ability to offer an easy “instant shipping” option on their checkout page—without worrying about logistics. They use existing infrastructure and last-mile delivery networks to help customers order now AND get it now. Shipsi was founded in 2017 and is headquartered in Austin, TX.
• Ceemo — Ceemo - Ceemo's simple 5-step quiz generates a complete brand & all the foundational marketing assets your small biz needs in just 10 minutes or less.

Portfolio highlights

• Meati — Meati Foods is a consumer goods company that offers carbon materials, bioengineering, and filtration. It focuses on using proprietary, clean technologies to provide nutrient-dense, plant-based meat alternatives that everyone can enjoy and feel good about eating every day.
• Branch Energy — A tech-powered, green energy provider focused on helping consumers reduce their energy bills and carbon footprints
• MineSense Technologies — MineSense Technologies is a developer of a data analytics platform intended to monitor and improve the productivity and recovery of mines. The company's platform provides businesses with real-time, sensor-based sorting of low-grade ore to a level of sensitivity and to identify differences in mineralogy, enabling the mining industry to sortores easily and enhance mineral planning.MineSense Technologies was founded in 2008 and is headquartered in Vancouver, Canada.

Portfolio highlights

• Pryon — Pryon is the leading AI-as-a-Service platform for content and knowledge management. Pryon closes knowledge gaps, improving employee productivity, and enhancing customer experiences. Companies such as Georgia Pacific use Pryon to improve health and safety outcomes, eliminate compliance incidents, improve employee onboarding, and upgrade all aspectsof customer service and support.
• Obsidio — Obsidio™ Conformable Embolic with aqueous gel technology is a 510(k) cleared device, the first of its kind to have a specific on-label indication for peripheral use in the U.S.
• AdipoPharma — AdipoPharma SAS is dedicated to learning more about the role of adipocyte cells in diabetes. AdipoPharma is using the adipocyte's power to treat insulin resistance, type 2 diabetes, and other diseases.

Portfolio highlights

• Daily.co — Daily is a WebRTC developer platform. Our APIs let you build video and audio into any application, solving for scaling, media quality and compliant infrastructure. You can add a fully working video call with two lines of code. Our lower-level APIs give you total UI/UX flexibility and global servers where you need them. Start by cloning our sample repos.
• Privacy Dynamics — Data privacy tools built for analytics engineers and the modern data stack.
• Superconductive — The team behind Great Expectations.

Portfolio highlights

• P-1 AI — P-1 AI is a technology company focused on developing an artificial general engineering intelligence (AGEI) designed to help humanity design physical systems with far greater efficiency and complexity than currently possible.
• CVector — Stream, model, and act on your energy and industrial data in real time. CVector unifies asset and market data so you can make faster, smarter project decisions.
• Harbinger — Founded by veterans of Canoo and Faraday Future, Harbinger is an automotive company that develops EV platforms optimized for medium-duty trucks and delivery vans.

Portfolio highlights

• PeelON — At PeelON, we're passionate about freshness, sustainability, and innovation. Our mission is to revolutionize the packaging industry by offering biodegradable solutions that keep produce fresher for longer while minimizing environmental impact. With PeelON, you can trust that your fruits and vegetables stay crisp, delicious, and planet-friendly. Join us in our journey towards a fresher, greener future. - Biodegradable covers - food packaging - biodegradable food packing - fresh fruit covers
• Queens Carbon — Queens Carbon is working on a processing system that will dramatically cut energy use. The system minimizes calcination and material synthesis energy consumption, allowing for low-cost carbon capture and carbon-neutral cement manufacture.
• Electrified Thermal Solutions — Electrified Thermal Solutions, Inc. is developing the Joule Hive: a new energy storage technology that converts surplus zero-carbon electricity into heat.

Portfolio highlights

• Pryon — Pryon is the leading AI-as-a-Service platform for content and knowledge management. Pryon closes knowledge gaps, improving employee productivity, and enhancing customer experiences. Companies such as Georgia Pacific use Pryon to improve health and safety outcomes, eliminate compliance incidents, improve employee onboarding, and upgrade all aspectsof customer service and support.
• Kanarys — Kanarys fuels progress towards more diverse, equitable and inclusive workplace cultures
• Cambium — Saving wood to save the planet. By revolutionizing supply chains, we introduce the world's first carbon smart material.

Portfolio highlights

• LineWise — LineWise is a AI Engineer troubleshoot system that helps manufacturers maximize production uptime.
• zeroRISC — ZeroRISC operates as a stealth start-up making hardware security foundations transparent and trustworthy.
• Unbound Security — Discover, assess, and govern AI coding agents across your org. Unbound is the first Agent Access Security Broker (AASB). Get a free scan in 5 minutes.

Portfolio highlights

• Venseca — Venseca is a global leader in digital trust. Our patent-pending solution generates Digital Trust Scores and comprehensive, independently validated reports to help you understand the cyber risk profile of all of your suppliers.
• UnityLab — Welcome to UnityLab, home of the best small business & brand builders dedicated to business technology, operations, finance, & sales tools.
• Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi

Portfolio highlights

• RebelMouse — RebelMouse is the first digital publishing platform that is fully wired for social. Its solution enables brands, media companies and individuals to create vibrant content experiences that build communities and continually reach and grow audiences across the social web.Unlike conventional approaches that focus on managing content workflows withinspecific channels, RebelMouse liberates content across sites, social, apps and ads, and amplifies engagement with intelligent recommendations, social calls to action, real-time trending alerts and more.Founded in 2012 by former Huffington Post CTO Andrea Breanna, RebelMouse's modern approach to traffic helped create huge online hits like Axios and The Dodo, while also relaunching existing publishers like PAPER Magazine and helping them "Break the Internet." RebelMouse also helps brands who want to act more like a media company, including helping United Airlines Hub become the most popular airline blog.For more information, visit rebelmouse.com and follow RebelMouse on Twitter at @rebelmouse.
• Expressable — Expressable is an online speech therapy practice for everyone with a communication disorder. It has pioneered a parent-focused care model that uses technology and education to integrate speech therapy techniques into children's daily lives, improving outcomes and experiences.The company was founded in 2019 and is headquartered in Austin,Texas.
• Bookkeep — Whether you run multiple locations, franchise stores, or sell across channels, Bookkeep automates your revenue recognition, deposit reconciliation and sales tax compliance with 100% accuracy.

Portfolio highlights

• Elate — Elate is the first Strategic Planning software built to help SaaS companies communicate their vision, create alignment, and track performance all in one place.
• Haven — Haven is a free, intuitive mobile app and website that equips homeowners with predictive technology to be better homeowners. It provides value to both do-it- yourself inclined homeowners by providing an individualized reminder and tracking system, as well as homeowners who need help, by providing licensed, insured, pre-vetted service professionals,scheduling services, and accepting payment--all without ever leaving the app. Haven gives homeowners confidence and peace of mind to be responsible and proactive in home maintenance decisions.
• Parker Technology — We bridge the gap between you and your parking guests. When automation gets confusing, we send a human to the rescue. All those customer service calls? They're resolved in under a minute.

Portfolio highlights

• Tasktop — Tasktop offers a software platform that allows companies to better manage the process of building their software. Tasktop plugs into existing tools and overlays the end-to-end value stream to provide the abstractions, automation, visualizations, and forensics needed to practice value stream management on a daily basis.
• Ambiq Micro — Ambiq has developed breakthrough technology innovating battery-powered endpoint devices by reducing the total power consumed. Learn more.
• Veros Systems — Veros Systems enables industrial customers to maximize production by providing actionable intelligence on their electrically-driven machines.Their web-based Predictive Intelligence Platform uses completely nonintrusive monitors that can be installed in hours. PIP offers real-time predictive reliability and energy efficiency intelligence onelectromechanical systems, and seamlessly integrates with leading Enterprise Asset Management applications. At last, engineers, managers, and executives have a means to see the future: to plan better, reduce costs, and improve a facility’s overall availability.

Portfolio highlights

• mParticle — mParticle by Rokt is the choice for multi-channel consumer brands who want to deliver intelligent and adaptive customer experiences in the moments that matter, across any screen or device.
• ZeroBrush — Clean every surface of your teeth, every time, all at once. ZERObrush is a groundbreaking oral care mouthpiece built from a 3D model of your teeth and designed to clean the hard to reach places better than a manual toothbrush.
• Propeller Health — Propeller Health is a mobile platform that offers sensors, mobile apps, analytics, and services to support respiratory health management. The HIPAA compliant platform stores users’ data in a cloud computing infrastructure.The Propeller sensor and mobile application help users learn more about and better manage their asthma, COPD, andrespiratory disease. The Propeller sensor attaches to users’ inhalers and wirelessly syncs with their smartphones. It tracks their triggers and symptoms and sends personalized feedback and education to their phones based on the symptoms. Users can see how often they use the medication, and set up medication reminders and alerts.Propeller community enables users to share their Propeller data with their physician and family members.Propeller Health is backed by Safeguard Scientifics, The Social+Capital Partnership, California HealthCare Foundation, and other investors.  The platform works with organizations such as Dignity Health, Wyckoff Heights Medical Center, Amerigroup Florida, and the City of Louisville. The system has been featured in The Economist, Washington Post, Fast Company, Wired, and Scientific American.Propeller Health has received TEDMED Innovation Showcase, White House Champion of Change, and Bluetooth Breakthrough Product awards.Propeller Health was launched by David Van Sickle, Greg Tracy, and Mark Gehring and its operations are based in Wisconsin, United States.

Portfolio highlights

• Iron Ox — Solving global climate through our food, grown renewably, using technology
• Material — Unlocking embedded power at any shape
• Framework — Framework is an electronics company that repairs lightweight laptops and consumer electronics products. The company is building people and planet-friendly consumer electronics products that are designed to be easy to upgrade, customize and repair. Their first product is the Framework Laptop, which has received an incredible response from the pressand consumers (including recently landing on the cover of TIME's Best Inventions of 2021).

Portfolio highlights

• Firestorm — Democratizing deterrence through the use of radically affordable, mission-adaptable unmanned aerial systems (UAS) and answering the call for future-proofed systems with open system architectures.
• Launchpad.build — Prototype, pilot and scale hardware faster, easier and at a lower cost than ever before. Launchpad delivers assembled products using advanced AI software and automation within weeks, instead of months or years.
• Phoenix Semiconductor — Phoenix Semiconductor recreates obsolete microelectronics on demand and at scale for the defense, transportation, infrastructure, oil & gas and OEM markets.

Portfolio highlights

• Latus Bio — Latus Bio focuses on developing innovative gene therapy candidates using precision delivery to enhance the lives of patients. Latus identified proprietary AAV capsids for clinical use. The company plans to administer low doses of its product candidates, aiming to improve clinical safety and manufacturing.
• DataHub — DataHub Core is the #1 open source platform with a uniquely scalable and extensible metadata graph supporting manual and automated data management. DataHub Cloud is an enterprise-ready SaaS solution providing a fully-managed service of DataHub Core with additional AI-powered capabilities in discovery, observability, and governance to accelerateproduction-readiness of AI and data assets.
• Flywheel.io — Flywheel is a data management and analysis platform built specifically for scientists and the researcher's workflow. They empower research momentum by focusing on data and medical image capture, content management, scientific computation, and collaboration. With reproducible research in mind, they combine open-source methods from topuniversities, a modern web user interface, and an extensible compute engine based on containerization technology. The result is a software platform to accelerate discovery and help researchers do science, not IT.Flywheel accelerates new scientific discoveries in life-science, biotech, and academic imaging research through cloud-scale collaboration. As a result, imaging researchers are able to avoid innovation bottlenecks, and accelerate discovery by doing more science, and less IT.