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Top 50 Manufacturing Startup Investors in United States in December 2024

Last updated: Dec 2024 A list of 50 angel investors and VC (Venture Capital) funds that invest in Manufacturing startups based in United states. We rank investors based on the number of investments they made in Manufacturing companies from United states. We update this investor list every month.

Top 50 Manufacturing Startup Investors in United States in December 2024

Investor	Manufacturing United States investments
SOSV	61
Lux Capital	31
Alumni Ventures	29
Innova Memphis	28
Founders Fund	23
New Enterprise Associates	23
Toyota Ventures	23
Khosla Ventures	23
Clean Energy Ventures	22
Houston Angel Network	22
Fifty Years	21
Intel Capital	20
Flybridge	20
Breakthrough Energy Ventures	20
Prelude Ventures	18
Advantage Capital	18
Asymmetry Ventures	18
Eclipse Ventures	18
Maine Angels	18
Root Ventures	16
Congruent Ventures	16
The Engine	16
Climate Capital	16
Creative Ventures	16
Kleiner Perkins	16
MB Venture Partners	16
Right Side Capital Management	16
Threshold	15
Schematic Ventures	15
Sequoia Capital	15
Revolution’s Rise of the Rest Seed Fund	14
Clean Energy Venture Group	14
Cantos	14
Ben Franklin Technology Partners of Northeastern Pennsylvania	14
Mark Cuban	14
Collaborative Fund	14
Good Growth Capital	14
Social Capital	14
Draper Associates	14
DCVC	14
The Engine	14
Alliance of Angels	13
Lerer Hippeau	13
Bolt	13
Liquid 2 Ventures	13
BoxGroup	13
Texas HALO Fund	12
180 Degree Capital	12
U.S. Venture Partners	12
Safar Partners	12

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Investor list

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Biotechnology
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Shiru — Discover Shiru. We are an Ingredient Company that Identifies and Creates Functional Ingredients for the Plant-Based Industry.
Enveda Biosciences — Enveda Biosciences is a biotechnology company building new medicines from plants. It harnesses the complexity of the natural world to tackle today’s biggest healthcare challenges. With the help of the advancements in knowledge graphs, machine learning, and metabolomics, they discover the next generation of small molecules. Its technologiessystematize the discovery of small molecules and novel targets for complex diseases. By probing novel chemical space and mechanisms of action, they are breaking the status quo for challenging diseases with a need for effective treatments, such as fibrosis or neurodegeneration.Enveda, launched in 2019, is based in San Francisco, California.
Physical Intelligence — Physical Intelligence is bringing general-purpose AI into the physical world.

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Cake AI — Cake is the fastest way to drive AI initiatives to success. Cake manages the entire stack - compute infrastructure, open source platform elements, common integrations, and pre-built project components.
Rosie AI — Rosie is ChatGPT for Excel—your on-call expert business analyst. She integrates seamlessly with your spreadsheets to build, update, and explain complex Excel models. Whether you're aiming to streamline data analysis or automate repetitive tasks, Rosie is designed to boost productivity and sharpen decision-making. With Rosie, Excel becomes lessabout wrestling with formulas and more about driving strategic insights.
StoreCash — StoreCash is a digital bank built for teens and young adults. Unlock massive cashback rewards & learn financial literacy by signing up.

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.
Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Even — Even is a health tech company and healthcare provider that partners directly with the top hospitals in the country to offer you unlimited diagnostics, consultations, and 50 lakh worth of hospitalisations all with one monthly subscription cost.
Impulse Space — Economical and nimble last-mile space payload delivery

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, China

Portfolio highlights

Sana — Sana is an AI company building the next generation of knowledge tools. Designed and engineered in Stockholm, Sweden.
Fastino — Fastino provides enterprise AI developers with high-performance, task-optimized language models built to scale.
Avenzo Therapeutics — Developing the next generation of oncology therapies for patients.

Toyota Ventures is a San Francisco Bay Area-based venture capital firm that invests in early-stage startups from around the world. Founded in July 2017, its mission is to discover what’s next for Toyota by helping startups bring disruptive technologies and business models to market quickly. With more than $500 million in assets under management,the firm’s funds include the Toyota Ventures Frontier Fund focused on artificial intelligence, cloud computing, autonomy, mobility, robotics, smart cities, digital health, financial technologies, materials, and energy; and the Toyota Ventures Climate Fund focused on innovative solutions for carbon neutrality.

Investment focus

Artificial Intelligence, Software, Robotics
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Ecolectro — Ecolectro is solving the biggest challenges in making Green Hydrogen. Our alkaline ion-exchange membranes and polymers make clean fuel and decarbonize industry.
Pickle Robot — We make robots that unload trucks without retrofitting the warehouse
Starfish Space — Starfish Space: We're developing the first on-demand fleet of versatile and efficient space tugs prepared to service on-orbit satellites. --- Active life extension, debris removal, autonomous transportation

Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Moonvalley — The imagination research company building ML video and image models that captivate.
Vitara Biomedical — Vitara Biomedical has developed a therapeutic platform to support premature infants. Vitara Biomedical's platform was inspired by natural physiological processes to transform neonatal care.
Outsmart Education — Join the waitlist and see why higher education will never again be the same.

Clean Energy Ventures invests in scalable early-stage climate tech startups and clean energy technologies addressing global climate change.

Investment focus

Energy, Manufacturing, Renewable Energy
Seed, Series A, Funding Round
United States, Canada, Israel

Portfolio highlights

Lithios — Lithios is developing systems based on breakthroughs in electrochemistry to selectively capture and release lithium from complex mixtures.
Transaera — Transaera is developing a new class of affordable, energy-efficient, sustainable cooling systems and residential air conditioners.
ConnectDER — ConnectDER adapters let anyone connect solar panels or EV chargers to their home at a fraction of the typical time and cost....

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

WE BACK HEROES using technology to solve the world's biggest problems

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Germany, Canada

Portfolio highlights

Aalo Atomics — Creating abundant and dependable clean energy to power humanity for generations.
BillionToOne — We are a team at the forefront of disease detection focused on moving Prenatal Screening and Liquid Biopsy forward.
Waypoint Bio — Waypoint's proprietary spatial multi-omics platform enables us to solve critical issues around understanding how cell therapies navigate the three-dimensional tumor microenvironment and allow the measurement of cell-to-cell interactions.

Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies. Since 1991, Intel Capital has invested US$12.9 billion in more than 1,582 companies worldwide.Intel Capital has adopted the Diversity Term Sheet Rider.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

Cherre — Connect all your real estate data and make it available to the entire organization for better investment, management, and underwriting decisions.
Tuskira — Tuskira provides cutting-edge threat defense system using a security mesh driven by AI.
Freshpaint — Codelessly connect your site or app to over 100+ integrations for analytics, advertising, email, warehousing, and more with one click. Automate site instrumentation and tedious integrations. Try free today.

Flybridge is an early-stage venture capital fund with 20+ years of investing experience and over $1B under management. Flybridge has offices in New York and Boston.

Investment focus

Software, Artificial Intelligence, SaaS
Seed, Series A, Series B
United States, Brazil, Canada

Portfolio highlights

Agtonomy — Agtonomy is a hybrid autonomy and tele-assist platform for agriculture vehicles.
Noetica AI — Instant benchmarking for the terms of your next deal. Leveraging the industry's largest knowledge graph of corporate debt, securities, and M&A transaction terms.
ForceMetrics — ForceMetrics keeps communities safe by providing first responders and city leaders with the critical context they need.

Focused on developing and deploying the critical climate solutions our world needs to reach net-zero emissions by 2050.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Series B, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

LuxWall — LuxWall is accelerating the global transition to net zero by upgrading windows and glass into transparent insulation for buildings.
NitroVolt — NitroVolt: the next generational step of sustainable ammonia.
RedoxBlox — RedoxBlox offers thermochemical energy storage technology for natural gas power plant operators. It helps power plant operators drastically reduce carbon and nitrogen oxides emissions, its solution integrates with the existing natural gas power plant infrastructure, minimizes impact on plant total capital costs, increases grid resiliency andsafety, and is recyclable, non-toxic, and non-combustible, enabling industries with renewables grid through the deployment of large-scale long-duration energy storage.The company was founded in 2020 and is based in East Lansing, Michigan.

Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. For us, climate is everything.

Investment focus

Software, Energy, Manufacturing
Series A, Series B, Series C
United States, Canada

Portfolio highlights

LuxWall — LuxWall is accelerating the global transition to net zero by upgrading windows and glass into transparent insulation for buildings.
RedoxBlox — RedoxBlox offers thermochemical energy storage technology for natural gas power plant operators. It helps power plant operators drastically reduce carbon and nitrogen oxides emissions, its solution integrates with the existing natural gas power plant infrastructure, minimizes impact on plant total capital costs, increases grid resiliency andsafety, and is recyclable, non-toxic, and non-combustible, enabling industries with renewables grid through the deployment of large-scale long-duration energy storage.The company was founded in 2020 and is based in East Lansing, Michigan.
Form Energy — Form Energy is developing, manufacturing, and commercializing a new class of cost-effective, multi-day energy storage systems.

Advantage Capital has invested over $3.8 billion in more than 800 portfolio companies and projects nationwide since 1992. The firm specializes in growth equity, lending, and mezzanine debt capital investments spanning three distinct but complementary themes, driving local economic development and lasting impact in underserved communities.____________________Growing Small Business // 800+ PORTFOLIO COMPANIES // 34 STATES // 66,000+ JOBS SUPPORTED // Small businesses and the entrepreneurs who power them are fundamental to the U.S. economy, driving inclusive economic expansion that allows people and communities to thrive. Advantage Capital offers debt and equity investment opportunities and can provide senior, unitranche and subordinated debt, as well as minority equity financing. The firm invests in companies from a diverse array of industry sectors, including manufacturing, technology and business services, among others. It seeks to make an initial investment between $500K and $10M in companies with $1M+ EBITDA.Financing Affordable Homes // 89 PROJECTS SINCE 2015 // 8,000+ FAMILIES & SENIORS HOUSED // 7 STATES // Creating stronger communities goes beyond business investment and jobs. Financing housing in these same communities creates even more positive and lasting impacts.Expanding Renewable Energy Solutions // $130M IN CAPITAL DEPLOYED // 65 PROJECTS // 20,000+ HOMES POWERED // Increased access to renewable energy supports local green jobs and economic development while building the framework for tomorrow's carbon-free America. ____________________Geographic Focus: Advantage Capital is committed to impact nationwide, with current emphasis in the following states: Alabama, Arkansas, Connecticut, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Mexico, Ohio, Pennsylvania, Tennessee, Texas, Utah, Virginia, West Virginia____________________Advantage Capital is headquartered in New Orleans, Louisiana and has offices in the following locations: St. Louis, MO; New York, NY; Austin, TX; Hanover, NH; Washington, D.C.; Napa, CA; Nevada.

Investment focus

Manufacturing, Software, Health Care
Debt Financing, Funding Round, Series A
United States, China, Canada

Portfolio highlights

Cloverleaf.me — Cloverleaf helps build great work teams and improve employee engagement using assessments like Enneagram, DISC and 16-Types to identify team strengths and coach work teams to work better together.
Whitman Controls — Whitman Controls specializes in the manufacture of miniature pressure, vacuum, temperature, and liquid level switches and sensors.
Malones CNC Machining Inc. — Malone's CNC Machining Inc. is a manufacturer of military aircraft parts and assemblies.

Asymmetry Ventures invests in scalable early-stage companies with exceptional defensibility.

Investment focus

Software, Health Care, Biotechnology
Seed, Pre-Seed, Series A
United States, India, United Kingdom

Portfolio highlights

TransCrypts — We all have that file box where we throw all our important documents. Our goal at TransCrypts is to make that box digital and have all the documents secured through the blockchain. We currently offer industry leading privacy and security standards on our file storage and sharing platform and have solutions for individuals all the way to enterprises.
Reforged Labs — Reforged Labs | Effortless AI Ads for Mobile Game Studios.
SFA Therapeutics — SFA Therapeutics is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.

Palo Alto based Eclipse Ventures partners with entrepreneurs boldly transforming the essential industries that define and propel economies. Learn more.

Investment focus

Software, Robotics, Artificial Intelligence
Series A, Series B, Seed
United States, Canada, Israel

Portfolio highlights

DataPelago — DataPelago provides big data analytics solutions. They also provide a data analytics platform that offers hardware and software based products. The platform also provides solutions for extracting insights from data of, speed, or structure at performance and cost levels unsurpassed in the industry.
Quantum Source — Quantum Source is on a clear path to the most powerful, cost-effective, practical photonic quantum computer. Learn more.
Simbe Robotics — Better retail for all. Get shoppers what they want, your teams what they need, and brands what they've been craving.

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

Investment focus

Software, Health Care, Biotechnology
Seed, Funding Round, Series A
United States

Portfolio highlights

HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Root Ventures is a seed-stage venture capital firm that invests in technical teams working on deep tech. The firm specializes in the fields of financial services, venture capital, and investments. It was founded in 2013 and headquartered in San Francisco, California.

Investment focus

Software, Artificial Intelligence, Machine Learning
Seed, Series A, Series B
United States, Canada, Denmark

Portfolio highlights

Trieve — Trieve provides search teams with infrastructure for retrieval and RAG.
Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.
CruxOCM — Crux OCM: Automate your oil and gas control room operations

Congruent Ventures is a venture capital firm that seeks to invest in Mobility and Urbanization, Energy Transition, Food and Agriculture, and Sustainable Production & Consumption sectors. We look for technology companies that will positively impact our energy and resource consumption. If we see an opportunity to partner with a like-minded teamfocused on scale across hardware, software, or services, we’re interested.

Investment focus

Software, Energy, Renewable Energy
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

AMP — AMP Robotics creates a scalable robotic system that reduces the cost of recycling and enables smart recycling facilities. AMP Robotics' solution is a combination of computer vision and machine learning with robots that can identify and rapidly pick recyclable materials off a conveyor belt for market and recovery.AMP Robotics automates theidentification, sorting, and processing of material streams to extract value for material recovery facilities (MRFs) that process municipal solid waste, construction and demolition, e-waste, and auto-shredding. The company's engineering design reduces the cost of capital investment with modular implementation easily dropping into existing facility infrastructure without costly retrofits or interruption to operations.AMP Robotics was founded on 2015 and is headquartered in Louisville, Colorado.
Demex — Extreme weather is escalating but protection has not kept pace. Climate change is disrupting insurance and Demex is reshaping the market.
Energetic Capital — Let us cover the payment default risk on your next Solar Project. Energetic Insurance makes efficient financing possible for financiers, investors and energy service providers with the EneRate Credit Cover solar insurance policy.

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Amide Technologies — Amide synthesizes peptides that are difficult to obtain through existing means, bridging the gap between traditional solid phase peptide synthesis and biological expression. By using unnatural amino acids and artificial protein backbones, our team is expanding what is biologically possible. Amide’s Automated Fast Flow Peptide Synthesizer (AFPS)leverages flow to dramatically improve solid phase peptide synthesis. Using the power of flow, we can generate highly reactive intermediates in situ, maintain excellent heat and mass transfer, and achieve much better synthetic outcomes than alternative SPPS methods. With all these advantages, AFPS allows biopharma pioneers to dramatically re-think what’s possible. Let Amide broaden your horizons with better, faster synthesis.
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Climate Capital is an investment firm that supports companies that directly or indirectly reduce global greenhouse gas emissions.

Investment focus

Energy, Manufacturing, Biotechnology
Seed, Pre-Seed, Series A
United States, Germany, Canada

Portfolio highlights

Circe — Circe grows their food through fermentation. Using the right fats they make food people want to eat and use CO2 as a feedstock to scale production in an economically viable and climate-friendly way.
Zitara — Zitara builds software that empowers companies to deeply understand their batteries, both in design and deployment. We support the renewable energy revolution, powered by safer batteries, at a lower cost, with less waste.
Rosy Soil — Rosy Soil is a gardening solution focused on sustainable practices that support the health of soil, plants, and the environment.

Creative Ventures is a deep tech venture firm investing in early-stage companies solving humanity’s most critical crises. Led by a team of world-class experts, our deep tech acumen is informed by rigorous research, unmatched market understanding, and the dedication to lead our companies to success.Today’s problems can’t be solved by yesterday’ssolutions. Let’s get Creative.

Investment focus

Software, Health Care, Biotechnology
Seed, Series A, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

Relectrify — Unlocking extra lifetime and performance of batteries via advanced battery management (BMS) technology.
Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.
Picnic — The Picnic Pizza System is a modular, easy-to-use, automated pizza assembly system that saves time, money, and labor without compromising quality.

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

juna.ai — AI Agents to Run Your Factory
Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.
Browserbase — Browserbase is a comprehensive platform for developers to host, administer, and monitor headless browsers in the cloud.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
UBILD — A.I powered construction workforce and vendor procurement platform
Hutsy — Hutsy is your go-to financial app, offering personalized financial guidance based on your unique situation. Our mission is to help you improve your financial health through tailored advice on spending, savings, credit building, investing, debt management, and more.

Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs to build innovative consumer, enterprise, and healthcare technology companies.

Investment focus

Software, Internet, Mobile
Series B, Series A, Series C
United States, India, Canada

Portfolio highlights

Mendaera — Mendaera enables all healthcare providers to perform precise and consistent point-of-care interventions. Their platform combines real-time imaging, robotics, and artificial intelligence to aid physicians in image acquisition and interpretation.
Numa — Turns BDCs and Advisors into world-class communicators, using visibility + accountability + a healthy dose of AI superpowers
Numa — Leverage modern Generative-AI to autonomously capture every RO, schedule service appointments, and deliver service updates in real time.

Early-stage venture capital fund focused on investments in technology companies within the supply chain, manufacturing and digital industrial sectors

Investment focus

Software, Logistics, Supply Chain Management
Seed, Series A, Pre-Seed
United States

Portfolio highlights

Pandion — Pandion has developed a technology platform for e-commerce players to manage capacity problems during peak periods. The logistics platform helps all businesses provide one and two-day shipping, and makes on-time delivery possible for more retailers, regardless of size and scale. Pandion’s delivery management software uses machine learning to avoidshipping delays and optimize delivery networks.
Wilya — Reimagine the future of Industrial Work. ; Unlock Talent Pools. Millions of people are not able to work 8 hours a day or 5 days a week. ; Increase Diversity. Gig and Take helps you create and mange a flexible workforce.
Reshape Automation — AI-powered industrial automation marketplace and platform that simplifies the discovery, design, deployment, and support of automation

We help the daring build legendary companies.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, China, India

Portfolio highlights

Roon — Your Trusted Guide for Health Conditions. Today we are focused on GBM, ALS, Dementia, and Fertility and Family Building.
Eon — Meet Eon, the next-generation cloud backup solution with the first-ever backup autopilot for cloud infrastructure. We empower organizations with cloud backup posture management (CBPM), making complex backups simple and turning them into valuable, easily accessible assets.
AMP — AMP Robotics creates a scalable robotic system that reduces the cost of recycling and enables smart recycling facilities. AMP Robotics' solution is a combination of computer vision and machine learning with robots that can identify and rapidly pick recyclable materials off a conveyor belt for market and recovery.AMP Robotics automates theidentification, sorting, and processing of material streams to extract value for material recovery facilities (MRFs) that process municipal solid waste, construction and demolition, e-waste, and auto-shredding. The company's engineering design reduces the cost of capital investment with modular implementation easily dropping into existing facility infrastructure without costly retrofits or interruption to operations.AMP Robotics was founded on 2015 and is headquartered in Louisville, Colorado.

Investing catalytic capital in promising seed stage companies located outside of Silicon Valley, NYC & Boston. Backed by a group of iconic entrepreneurs, executives & investors.

Investment focus

Software, SaaS, Information Technology
Seed, Series A, Funding Round
United States, Canada, Argentina

Portfolio highlights

GovSky — Building cybersecurity technology to secure America’s supply chain.
Knit — Knit helps researchers run agency-quality quant + qual research at DIY costs, by taking the most time-intensive research tasks off their plate through Researcher-Driven AI.
Sigo Seguros — Sigo uses data and automation to provide lower-cost policies for the Latino market.

CEVG is an angel investor collective that invest in and mentors early-stage cleantech and climatetech startups across North America.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Seed, Funding Round
United States, Canada

Portfolio highlights

VoltServer — VoltServer develops innovative power distribution products based on the company's patented Digital Electricity technology. It is a venture-backed technology leader reinventing how electrical energy is distributed. VoltServer's patented Digital Electricity solutions deliver touch-safe electricity where, when, and how it is needed. DigitalElectricity can be delivered using an off-the-shelf data cable, at a significantly reduced cost, and with greater speed, power, distance, efficiency, intelligence, and flexibility, when compared to competing for electrical installations. VoltServer began shipping in early 2015 and is installed today powering 4G/LTE mobile services in many large sports stadiums, office towers, hotels, condominium, and medical buildings.
Cala Systems — Discover Cala, the innovative heat pump water heater that customizes heating to your lifestyle. Save money, reduce your carbon footprint, and enjoy easy installation with Cala. Reserve yours today and experience efficient, eco-friendly hot water tailored to your needs.
Carbon Upcycling — Carbon Upcycling Technologies (“CUT”) was formed to use the pollution of today to build the materials of tomorrow by converting CO2 gas into solid products. CUT sells advanced solid products derived from greenhouse emissions and cheaply available solids. Since 2014, CUT has scaled its ability to convert CO2 emissions into value-add end materials byover a million times. Through its portfolio of CO2-derived solid nanoparticles, CUT has technically validated its solutions for use in plastics, coatings, epoxy, adhesives, concrete, lithium-ion battery, and pharmaceutical industries. CUT recently launched a consumer brand called Expedition Air.CUT commercialized a corrosion-resistant coating, utilizing its nanoparticles, in 2017, becoming the youngest CO2 utilization company to generate commercial revenue (<2.5 years since inception) and has since been confirmed as one of the top CO2 utilization companies in the world as a winner of the X-Factor Award in the NRG COSIA Carbon XPRIZE. CUT has been named as a Solar Impulse Efficient Solution label recipient, a funding recipient of Fundación Repsol Entrepreneurs Fund, and a winner of the 2019 76West Clean Technology Competition.CUT’s most advanced product is its CO2-embedded concrete additive. In 2018, CUT graduated from the LafargeHolcim Accelerator in France and has continued conversations and testing with the company since then. CUT is also partnered with Burnco and Cemex. CUT’s commercial demonstration at the Alberta Carbon Conversion Technology Centre produces over 20 tonnes of concrete additives in a day. The product reduces the carbon footprint of concrete manufacturing by up to 25% while increasing the compressive strength of concrete by up to 40%.

Investing in the Near Frontier

Investment focus

Biotechnology, Software, Health Care
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Salient Motion — A next-generation supplier for aerospace and defense, specializing in advanced electric propulsion.
The Lumber Manufactory — Enabling timberland owners to get the most out of their land.
Intramotev — Intramotev Autonomous Rail manufactures autonomous zero-emissions rail vehicles to advance the future of freight movement. Intramotev's vehicles provide efficient and cost-effective movement of materials across specialized private railroads for mines, manufacturing facilities, ports, and more that is autonomous and fully battery-electric,enabling rail and mining industries to get lower emissions than diesel-electric locomotives and diesel trucks, shorter stopping distance, and steeper grade capability than existing trains.

Ben Franklin helps early-stage technology companies and established manufacturers translate innovation into commercial success and economic prosperity.

Investment focus

Manufacturing, Health Care, Software
Grant, Seed, Debt Financing
United States, United Kingdom, Brazil

Portfolio highlights

Venseca — Venseca is a global leader in digital trust. Our patent-pending solution generates Digital Trust Scores and comprehensive, independently validated reports to help you understand the cyber risk profile of all of your suppliers.
UnityLab — Welcome to UnityLab, home of the best small business & brand builders dedicated to business technology, operations, finance, & sales tools.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi

Mark Cuban is the founder of Fireside, Chairman and Founding Partner of AXS TV, and the Owner of Dallas Mavericks. He previously worked at Broadcast.com as a Co-Founder. Mark Cuban attended the Indiana University Bloomington.

Investment focus

Software, Artificial Intelligence, Blockchain
Seed, Series A, Angel
United States, United Kingdom, Singapore

Portfolio highlights

DIRT Research Technologies — DIRT is an AI-powered content measurement engine enabling AI models to recognize, evaluate, and generate content that grabs attention and predicts engagement. Linking human attention to images and videos, we teach models to understand what people are most interested in engaging with, watching, and playing. At DIRT, what you make matters. We makesure it connects.
TransCrypts — We all have that file box where we throw all our important documents. Our goal at TransCrypts is to make that box digital and have all the documents secured through the blockchain. We currently offer industry leading privacy and security standards on our file storage and sharing platform and have solutions for individuals all the way to enterprises.
Matter Intelligence — Matter Intelligence is creating the most detailed map of the world using first-of-a-kind sensors to understand our planet like never before

Collaborative Fund is a leading source of capital for entrepreneurs pushing the world forward.

Investment focus

Food and Beverage, Software, Health Care
Seed, Series A, Funding Round
United States, United Kingdom, South Korea

Portfolio highlights

Overlap — Overlap uses AI to help you extract the best moments from video content.
Acceleron Fusion — Acceleron Fusion provides clean energy solutions by using fusion technology.
Boston Materials — Explore cutting-edge advanced energy materials engineered for superior performance in aerospace, automotive, & electronics industries. Contact Us Today.

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

Investment focus

Health Care, Information Technology, Biotechnology
Seed, Series A, Convertible Note
United States, France, Israel

Portfolio highlights

Liminal — Advanced battery inspection and metrology with ultrasound and machine learning
Aralez Bio — Aromatic noncanonical amino acids that are made using biocatalysis. Single step, enzyme synthesis makes hundreds of tryptophan and other amino acid analogs!
AdipoPharma — By harnessing the power of the Adipocyte AdipoPharma is committed to developing innovative treatment for type 2 diabetes

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

Investment focus

Software, FinTech, Information Technology
Seed, Series A, Series B
United States, United Kingdom, Singapore

Portfolio highlights

Rosy Soil — Rosy Soil is a gardening solution focused on sustainable practices that support the health of soil, plants, and the environment.
CytoTronics — Visualize live cell function at scale for cell biology discovery with Pixel systems. Monitor cell viability, morphology, electrophysiology, metabolism and more.
Phaseshift Technologies — Phaseshift Technologies is developing a Computational Materials Engineering (CME) platform to help accelerate the Research and Development of High-Performance Alloys. The CME platform is driven by Quantum Chemistry calculations and aided by Machine Learning based predictive algorithms.

We are deep tech venture capital.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Q-CTRL — Infrastructure software to power the quantum future
Radiant — Clean. Portable. Safe. Energy
Reality Defender — Reality Defender is deepfake detection done right. With billions of visual and audio assets indexed, we offer the most robust deepfake detection available.

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Amide Technologies — Amide synthesizes peptides that are difficult to obtain through existing means, bridging the gap between traditional solid phase peptide synthesis and biological expression. By using unnatural amino acids and artificial protein backbones, our team is expanding what is biologically possible. Amide’s Automated Fast Flow Peptide Synthesizer (AFPS)leverages flow to dramatically improve solid phase peptide synthesis. Using the power of flow, we can generate highly reactive intermediates in situ, maintain excellent heat and mass transfer, and achieve much better synthetic outcomes than alternative SPPS methods. With all these advantages, AFPS allows biopharma pioneers to dramatically re-think what’s possible. Let Amide broaden your horizons with better, faster synthesis.
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Largest and most active angel group in the Pacific Northwest

Investment focus

Software, Health Care, Mobile
Seed, Funding Round, Series A
United States, Canada, Nigeria

Portfolio highlights

Glidance — Glide, a groundbreaking leap in assistive technology, is the first self-guided mobility assistant designed for individuals with sight loss.
Give InKind — Set up a Give InKind Page to coordinate support from anywhere. Create a Care Calendar, add items to your Wishlist and connect your Crowdfunding - all for free.
SafKan Health — OtoSet® by SafKan Health is the first FDA Cleared automated ear cleaning device for the 35 million Americans affected by impacted earwax - the leading cause of conductive hearing loss.

Lerer Hippeau is an early-stage venture capital fund based in New York City. As founders and operators ourselves, we see returns in relationships

Investment focus

Software, E-Commerce, Internet
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

MOTORMIA — Meet Mia! MOTORMIA - Curated by auto enthusiasts, powered by AI. MOTORMIA is revolutionizing personalized discovery of aftermarket upgrades for your enthusiast vehicle
Conflixis — Conflixis develops conflict monitoring platform intended to manage conflicts inside organizations.
Symbiotic Security — Symbiotic Security revolutionizes cybersecurity with an AI-driven coach, offering real-time detection, remediation, and training within the developer's IDE.

Bolt: Investing at the intersection of the digital and physical worlds

Investment focus

Software, Health Care, Hardware
Seed, Pre-Seed, Series A
United States, Canada

Portfolio highlights

FYTO — Revolutionary Sustainable Agriculture
Blackbird — We believe the next great hospitality technology platform should connect restaurants and their customers directly, in meaningful and ongoing ways. Blackbird is founded by a team with a passion for restaurants and a track record of using technology to solve problems.
Foundation — Self custody is finally attainable. Secure your Bitcoin with an unprecedented combination of elegance and ease of use.

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Pre-Seed
United States, Mexico, Canada

Portfolio highlights

Nodal — Nodal is a platform that efficiently connects vetted surrogates and intended parents, offering transparency, equity, education, and support for all parties on their journey.
Twenty — Experience the forefront of open-source CRM. Packed with advanced features, customizable workflows, and community support. Transform customer relationship management seamlessly and efficiently.
Attention — Attention is a powerful conversational intelligence software that helps you coach and ramp up your sales reps into top performers.

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

Investment focus

Software, Health Care, Internet
Seed, Series A, Series B
United States, France, Mexico

Portfolio highlights

Tempest DX — Tempest delivers a ready-to-use self-serve platform, empowering developers to automate building, deploying and managing their apps with built-in security and compliance. Tempest combines everything teams need from a service catalog and software ownership to powerful end-to-end automations, enabling organizations to accelerate time to market, boostproductivity, and maximize engineering ROI.
Tempest — Tempest is a ready-to-use self-serve platform that enables developers to automate app development, deployment, and management while ensuring security and compliance.
Jimini Health — Jimini’s mission is to radically improve the efficacy of mental health care across the world. Jimini has developed a novel care model that combines teletherapy sessions with personalized AI support. With Jimini, your therapy care team includes your licensed clinician and Sage, your always-available AI therapy assistant, who work together to helpyou achieve your goals.Founded in 2023 by a team of seasoned AI and biotech entrepreneurs, health tech veterans, and psychology researchers, Jimini puts science and tech first, using safe, purpose-built patient-facing technology that works exclusively under clinical oversight and high safety standards.World leaders in psychology designed Jimini’s care model to ensure that every part of the patient's journey is clinically beneficial. Jimini does not believe that LLMs should replace clinicians; rather, AI will help therapists deliver higher-quality care and focus on the most complex parts of their job. Jimini’s care model is first and foremost led by excellent clinicians.Jimini is committed to improving mental health quality and creating radically better, more modern, and clinically efficacious mental health experiences for patients.

Early Stage Venture Investments

Investment focus

Health Care, Medical Device, Software
Seed, Convertible Note, Series A
United States, Canada, Hungary

Portfolio highlights

Flourish Collective — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.

180 Degree Capital Corp. aims to capitalize on turn-around opportunities in micro-cap stocks with a constructive activist approach.

Investment focus

Manufacturing, Biotechnology, Health Care
Series B, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

ORIG3N — ORIG3N is a biotechnology company developing breakthrough treatments for rare genetically inherited diseases with targets in heart, liver, and neurodegenerative indications. It was founded in 2014 and is based in Boston, Massachusetts.
NGX Bio — NGX Bio is an online marketplace platform for online DNA sequencing services. They make sequencing simple by connecting their customers to world-class genomic resources helping researchers complete sequencing projects in a single transaction. It streamlines the projects and makes them cost-effective by sourcing the best providers with availablecapacity.NGX Bio offers design and planning, sample preparation, sequencing facilities, and data analysis services. The company also operates an online project management tool that helps in sample tracking by using barcoded tubes and plates. NGX Bio serves customers worldwide.
EchoPixel — EchoPixel, Inc. develops medical imaging devices. The company develops a non-invasive colon cancer screening solution that enables doctors and radiologists to use computed tomography (CT) images of a patient’s abdomen and display a 3D model of a patient’s colon. With this tool, any medical professional can examine the entire colon by using anavigate and detect approach to identify most polyps or other abnormalities, the cause of cancer. The company was incorporated in 2012 and is based in San Jose, California.

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

Investment focus

Software, Health Care, Information Technology
Series B, Series C, Series A
United States, Israel, Canada

Portfolio highlights

Stream Security — Empowering organizations to code and deploy configurations faster and safer, from plan to production.
Sepio — Sepio provides full asset visibility. Sepio's Asset Risk Management sees, assesses and mitigates risk for all known and shadow IT assets.
Sparrow Pharmaceuticals — Sparrow Pharmaceuticals is an emerging clinical-stage biopharmaceutical company developing novel, targeted therapies for disorders of corticosteroid excess.

Safar Partners is a seed- to growth-stage venture fund investing primarily in technology companies out of MIT, Harvard, and the University of Rochester. We invest in platform technologies in the cleantech and advanced materials, AI/IT and robotics, and life science/medical device areas.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States, China

Portfolio highlights

Circe — Circe grows their food through fermentation. Using the right fats they make food people want to eat and use CO2 as a feedstock to scale production in an economically viable and climate-friendly way.
Lucy Therapeutics — Lucy Therapeutics, a Boston-based biotech with a unifying mitochondrial platform, is developing small molecule treatments for neurological diseases.
Ancilia Biosciences — A CRISPR route to success for live biotherapeutics & bacterial products

Investors by industry

Artificial intelligence