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Top 50 Manufacturing Startup Investors in United States in April 2025

Last updated: Apr 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Manufacturing startups based in United states. We rank investors based on the number of investments they made in Manufacturing companies from United states. We update this investor list every month.

Top 50 Manufacturing Startup Investors in United States in April 2025

Investor	Manufacturing United States investments
SOSV	61
Alumni Ventures	31
Lux Capital	31
Innova Memphis	28
Founders Fund	24
Toyota Ventures	24
Khosla Ventures	24
Clean Energy Ventures	23
Houston Angel Network	22
Fifty Years	21
Intel Capital	20
Breakthrough Energy Ventures	20
Flybridge	19
Eclipse Ventures	19
Advantage Capital	18
New Enterprise Associates	18
Asymmetry Ventures	18
Prelude Ventures	18
Maine Angels	18
Congruent Ventures	17
Sequoia Capital	17
Creative Ventures	16
Root Ventures	16
Climate Capital	16
MB Venture Partners	16
Kleiner Perkins	16
The Engine	15
Right Side Capital Management	15
Collaborative Fund	15
Mark Cuban	15
Cantos	15
Schematic Ventures	15
Jackson Moses	14
Threshold	14
Good Growth Capital	14
Liquid 2 Ventures	14
DCVC	14
Draper Associates	14
Revolution’s Rise of the Rest Seed Fund	14
BoxGroup	14
Ben Franklin Technology Partners of Northeastern Pennsylvania	14
The Engine	13
Gaingels	13
Bolt	13
Propel(X)	13
Lerer Hippeau	13
Clean Energy Venture Group	13
Andreessen Horowitz	13
Social Capital	13
U.S. Venture Partners	12

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SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Patlytics — Patent discovery, analytics, comparison, and workflow. Simplified via Artificial Intelligence.
Ceramic.ai — Ceramic.ai builds enterprise-grade infrastructure to optimize how companies train and deploy their AI models
Prezent AI — Presentation productivity platform for enterprise teams. Add zen to your presentations!

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Biotechnology
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Lanai — The AI Empowerment Platform - Help your team achieve the extraordinary in the age of AI.
Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.
Frontera Health — Save 5-6 hours on every ABA diagnosis and assessment report. Frontera ABA clinical report automation software helps you spend more time with patients. Let our BCBA-trained AI do the heavy lifting.

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

ThreatMate — ThreatMate revolutionizes cybersecurity by offering a single platform with inquisitive security capabilities for the middle market. The company was founded by a team of serial entrepreneurs and cybersecurity experts that aims to protect mid-sized companies from cyber threats.
Biosphere — Biosphere engages in manufacturing commercial-scale fermentation products and robotic greenhouses.
Cognition — Cognition is an applied artificial intelligence lab that focuses on reasoning and code.

Toyota Ventures is a San Francisco Bay Area-based venture capital firm that invests in early-stage startups from around the world. Founded in July 2017, its mission is to discover what’s next for Toyota by helping startups bring disruptive technologies and business models to market quickly. With more than $500 million in assets under management,the firm’s funds include the Toyota Ventures Frontier Fund focused on artificial intelligence, cloud computing, autonomy, mobility, robotics, smart cities, digital health, financial technologies, materials, and energy; and the Toyota Ventures Climate Fund focused on innovative solutions for carbon neutrality.

Investment focus

Artificial Intelligence, Software, Robotics
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Holyheld — Holyheld is a onchain crypto debit card. The one card for all crypto natives. Get your card, pay from your phone, use your wallet, and pick your crypto.
Tereform — Tereform is a company that operates in the chemical engineering, manufacturing, and recycling industries. The company's mission is to enable textile-to-textile recycling, addressing the issue of textile waste. Tereform combines various technologies and processes to achieve this goal. The company is particularly focused on promoting circularitywithin the fashion and textile industries, aiming to reduce the environmental impact of these sectors.
Ecolectro — Ecolectro is solving the biggest challenges in making Green Hydrogen. Our alkaline ion-exchange membranes and polymers make clean fuel and decarbonize industry.

Khosla Ventures invests in companies that are bold, early, and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs.Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech, digital health, medtech anddiagnostics, therapeutics, and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Onyx — The open-source AI enterprise search platform that helps teams find information across all company data.
Tempero Bio — Tempero Bio develops treatments for Substance Use Disorders as a clinical-stage biopharmaceutical company.
Resource Chemical — Resource Chemical develops CO2 into high-performance plastics that do not pollute the environment. The company's headquarters are in Berkeley, California.

Clean Energy Ventures invests in scalable early-stage climate tech startups and clean energy technologies addressing global climate change.

Investment focus

Energy, Manufacturing, Renewable Energy
Seed, Series A, Funding Round
United States, Canada, Israel

Portfolio highlights

DG Matrix — DG Matrix innovative solutions unlock gigaton-scale emissions reductions by enabling electrification anywhere and everywhere with less material and a smaller footprint.
Advanced Ionics — Advanced Ionics has created an electrolyzer that allows industrial hydrogen users to produce green hydrogen for less than $1/kg.
Electrified Thermal Solutions — Electrified Thermal Solutions, Inc. is developing the Joule Hive: a new energy storage technology that converts surplus zero-carbon electricity into heat.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

WE BACK HEROES using technology to solve the world's biggest problems

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Germany, Canada

Portfolio highlights

Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
Aalo Atomics — Creating abundant and dependable clean energy to power humanity for generations.
Waypoint Bio — Waypoint's proprietary spatial multi-omics platform enables us to solve critical issues around understanding how cell therapies navigate the three-dimensional tumor microenvironment and allow the measurement of cell-to-cell interactions.

Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, Israel, China

Portfolio highlights

MaxIQ — With MaxIQ, revenue teams aren’t just forecasting closed deals — they’re managing the entire revenue lifecycle. Our AI-powered insights automatically surface risks, such as slow onboarding, stalled product adoption, or shifts in stakeholder engagement, enabling proactive intervention.By aligning Sales and Customer Success on a shared customerjourney workspace, MaxIQ ensures nothing falls through the cracks. Seamless handoffs, clear action plans, and real-time visibility into account health allow teams to accelerate time-to-value, increase adoption rates, and uncover expansion opportunities earlier.
Skylo — Never lose coverage again - connect your existing NB-IoT devices directly over both cellular and satellite networks seamlessly
Bria — Bria is a Computer Software company.

Focused on developing and deploying the critical climate solutions our world needs to reach net-zero emissions by 2050.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Series B, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

H2SITE — We provide fully integrated systems to produce on-site high quality hydrogen.
Mantle8 — Using bottom-up exploration and decades of geology experience, we are on a mission to deliver natural hydrogen to the world.
Mangrove Lithium — Mangrove Lithium is a ground-breaking refining platform that redefines the industry standard for battery grade lithium refining

Flybridge is an early-stage venture capital fund with 20+ years of investing experience and over $1B under management. Flybridge has offices in New York and Boston.

Investment focus

Software, Artificial Intelligence, Information Technology
Seed, Series A, Series B
United States, Canada, Brazil

Portfolio highlights

Riley — Riley learns and grows with your family, offering personalized, data-backed guidance so you're ready for anything that life - or your kids - throws your way.
Porosity — Porosity is an application software company that offers a platform to streamline operations management and data collection.
Teal — Free tools and resources to run a faster and better job search so you can focus your time and energy on finding and landing a job you will love.

Palo Alto based Eclipse Ventures partners with entrepreneurs boldly transforming the essential industries that define and propel economies. Learn more.

Investment focus

Software, Robotics, Artificial Intelligence
Series A, Series B, Seed
United States, Canada, Israel

Portfolio highlights

Gravity — Gravity Climate provides a software platform designed for carbon management, specifically tailored for industrial businesses and their supply chain partners. The platform helps companies measure, manage, and reduce their carbon emissions, facilitating a clear and actionable climate strategy. Gravity Climate's tools support decarbonizationefforts by streamlining carbon accounting processes and offering insights to advance industrial sustainability goals.
AheadComputing — AheadComputing is a company that specializes in designing, licensing, and providing support for high-performance microprocessor cores and related technologies.
Starboard — Starboard revolutionize global trade by empowering SMB freight forwarders with cutting-edge AI tools.

Advantage Capital has invested over $3.8 billion in more than 800 portfolio companies and projects nationwide since 1992. The firm specializes in growth equity, lending, and mezzanine debt capital investments spanning three distinct but complementary themes, driving local economic development and lasting impact in underserved communities.____________________Growing Small Business // 800+ PORTFOLIO COMPANIES // 34 STATES // 66,000+ JOBS SUPPORTED // Small businesses and the entrepreneurs who power them are fundamental to the U.S. economy, driving inclusive economic expansion that allows people and communities to thrive. Advantage Capital offers debt and equity investment opportunities and can provide senior, unitranche and subordinated debt, as well as minority equity financing. The firm invests in companies from a diverse array of industry sectors, including manufacturing, technology and business services, among others. It seeks to make an initial investment between $500K and $10M in companies with $1M+ EBITDA.Financing Affordable Homes // 89 PROJECTS SINCE 2015 // 8,000+ FAMILIES & SENIORS HOUSED // 7 STATES // Creating stronger communities goes beyond business investment and jobs. Financing housing in these same communities creates even more positive and lasting impacts.Expanding Renewable Energy Solutions // $130M IN CAPITAL DEPLOYED // 65 PROJECTS // 20,000+ HOMES POWERED // Increased access to renewable energy supports local green jobs and economic development while building the framework for tomorrow's carbon-free America. ____________________Geographic Focus: Advantage Capital is committed to impact nationwide, with current emphasis in the following states: Alabama, Arkansas, Connecticut, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Mexico, Ohio, Pennsylvania, Tennessee, Texas, Utah, Virginia, West Virginia____________________Advantage Capital is headquartered in New Orleans, Louisiana and has offices in the following locations: St. Louis, MO; New York, NY; Austin, TX; Hanover, NH; Washington, D.C.; Napa, CA; Nevada.

Investment focus

Manufacturing, Software, Health Care
Debt Financing, Funding Round, Series A
United States, China, Canada

Portfolio highlights

Umecc — Umecc offers a line of metallurgical equipment, spare parts, and refractories. The company operates a large variety of manufacturing facilities locally as part of its manufacturing group. Their products and services are provided individually or as a comprehensive package, including all engineering services.
Cloverleaf.me — Cloverleaf helps build great work teams and improve employee engagement using assessments like Enneagram, DISC and 16-Types to identify team strengths and coach work teams to work better together.
Whitman Controls — Whitman Controls specializes in the manufacture of miniature pressure, vacuum, temperature, and liquid level switches and sensors.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, Canada

Portfolio highlights

Ceramic.ai — Ceramic.ai builds enterprise-grade infrastructure to optimize how companies train and deploy their AI models
Vori Health — Meet Vori Health, the new virtual and in-person musculoskeletal healthcare company that will help you get that spring back into your step.
Ceramic — Next generation AI training systems for better models with less compute, less time, and lower costs.

Asymmetry Ventures invests in scalable early-stage companies with exceptional defensibility.

Investment focus

Software, Health Care, Biotechnology
Seed, Pre-Seed, Series A
United States, India, United Kingdom

Portfolio highlights

TransCrypts — We all have that file box where we throw all our important documents. Our goal at TransCrypts is to make that box digital and have all the documents secured through the blockchain. We currently offer industry leading privacy and security standards on our file storage and sharing platform and have solutions for individuals all the way to enterprises.
Reforged Labs — Reforged Labs | The world's first AI copilot For mobile game marketers
Coreshell Technologies — Battery Capacity Unlocked

Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. For us, climate is everything.

Investment focus

Software, Energy, Manufacturing
Series A, Series B, Series C
United States, Canada

Portfolio highlights

LuxWall — LuxWall is accelerating the global transition to net zero by upgrading windows and glass into transparent insulation for buildings.
Persefoni AI — Persefoni is a Climate Management & Accounting Platform (CMAP). The company's Software-as-a-Service solutions enable enterprises and financial institutions to meet stakeholder and regulatory climate disclosure requirements with the highest degrees of trust, transparency, and ease. As the ERP of Carbon, the Persefoni platform provides usersa single source of carbon truth across their organization, enabling them to manage their carbon transactions and inventory with the same rigor and confidence as their financial transactions.
Augmenta — Design sustainable, code compliant and fully constructible buildings in hours.

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

Investment focus

Software, Health Care, Biotechnology
Seed, Funding Round, Series A
United States

Portfolio highlights

HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Congruent Ventures is a venture capital firm that seeks to invest in Mobility and Urbanization, Energy Transition, Food and Agriculture, and Sustainable Production & Consumption sectors. We look for technology companies that will positively impact our energy and resource consumption. If we see an opportunity to partner with a like-minded teamfocused on scale across hardware, software, or services, we’re interested.

Investment focus

Software, Energy, Renewable Energy
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Presto — Presto is a software platform to power magical charging experiences for fleets, mobility providers, and businesses.We believe that access to reliable and affordable charging is the key to unlocking mass electrification and fighting climate change.
Bonsai Robotics — Bonsai Robotics provides vision-based automation solutions for off-road vehicles, such as agricultural machines. The company also offers analytics and telematics to help growers improve their performance, efficiency, and safety. The company is based in San Jose, California.
Adaptive insurance — Adaptive insurance, which begins with parametric insurance, seeks to transform how companies develop financial resilience in the face of weather-related and climate-related events. By combining our cutting-edge coverages, real-time climate data, and AI-driven technology, we think we can support them and show business consumers the benefits ofparametric insurance.

We help the daring build We help the daring build legendary companies from idea to IPO and beyond. companies.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, China, India

Portfolio highlights

Paid — Paid is a business platform for AI agents.
The Open Network Foundation — A decentralized and open internet designed to onboard 500M people on-chain, built by the community using technology developed by Telegram.
Neros Technologies — Neros is vertically integrating production of unmanned defense systems in the United States, securing the autonomous supply chain. Are you with us?

Creative Ventures is a deep tech venture firm investing in early-stage companies solving humanity’s most critical crises. Led by a team of world-class experts, our deep tech acumen is informed by rigorous research, unmatched market understanding, and the dedication to lead our companies to success.Today’s problems can’t be solved by yesterday’ssolutions. Let’s get Creative.

Investment focus

Software, Health Care, Biotechnology
Seed, Series A, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

Relectrify — Unlocking extra lifetime and performance of batteries via advanced battery management (BMS) technology.
Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.
Picnic — The Picnic Pizza System is a modular, easy-to-use, automated pizza assembly system that saves time, money, and labor without compromising quality.

Root Ventures is a seed-stage venture capital firm that invests in technical teams working on deep tech. The firm specializes in the fields of financial services, venture capital, and investments. It was founded in 2013 and headquartered in San Francisco, California.

Investment focus

Software, Artificial Intelligence, Machine Learning
Seed, Series A, Series B
United States, Canada, Denmark

Portfolio highlights

Trieve — Trieve provides search teams with infrastructure for retrieval and RAG.
Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.
CruxOCM — Crux OCM: Automate your oil and gas control room operations

Climate Capital is an investment firm that supports companies that directly or indirectly reduce global greenhouse gas emissions.

Investment focus

Energy, Manufacturing, Biotechnology
Seed, Pre-Seed, Series A
United States, Germany, Canada

Portfolio highlights

Rosy Soil — Crafted for the specific needs of indoor plants, this blend contains all-natural, renewable ingredients that optimize drainage, deliver plant-boosting nutrients, and support a diverse community of beneficial fungi and microbes.
Moment Energy — Moment is a start-up striving to provide greater access to renewable and reliable energy storage. We create battery units that can be used in a variety of applications. Moment is currently focused on storing energy for off-grid, end of grid customers, and plans on powering remote communities in the future.
Orpheus Ocean — The first AUV to unlock scalable seafloor access

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
Hippocratic AI — The First Safety Focused LLM for Healthcare

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

VEIR — Discover VEIR's cutting-edge technology for superconducting power lines that offer 5-10x greater transfer capacity and 90% less resistive line losses.
Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
UBILD — A.I powered construction workforce and vendor procurement platform
Hutsy — Hutsy Financial is a financial services company that provides mobile banking, early payroll access and credit building products. In partnership with Peoples Trust we provide a prepaid debit card that our users can spend with. We also offer cash back on all purchases, spending insights, and categorizations to provide valuable insight on where yourmoney is going. Hutsy was recently on CBC’s Dragons Den where we raised our pre-seed funding round of $500,000 to bring our product to life.

Collaborative Fund is a leading source of capital for entrepreneurs pushing the world forward.

Investment focus

Food and Beverage, Software, Health Care
Seed, Series A, Funding Round
United States, United Kingdom, South Korea

Portfolio highlights

Porosity — Porosity is an application software company that offers a platform to streamline operations management and data collection.
Pendulum Systems (formerly Macro-Eyes) — Pendulum Systems is an AI company building the first intelligent supply chain planning platform.Pendulum AI predicts demand, optimizes supply, and puts assets on the map, all while continuously improving on its own. Our technology is the result of a decade of rigorous research and development and has been deployed across some of the mostdemanding environments on Earth.Today, Pendulum is at work for corporations and governments across six continents, driving margins and saving lives.In 2023, Macro-Eyes became Pendulum, shifting from an R&D focus to productization and commercial growth.
Brightly Ventures — High-integrity carbon credits that fund food recovery in your community.

Mark Cuban is the founder of Fireside, Chairman and Founding Partner of AXS TV, and the Owner of Dallas Mavericks. He previously worked at Broadcast.com as a Co-Founder. Mark Cuban attended the Indiana University Bloomington.

Investment focus

Software, Artificial Intelligence, Blockchain
Seed, Series A, Angel
United States, United Kingdom, Singapore

Portfolio highlights

Fetii — Fetii is a group-centric rideshare app that allows groups to ride together using our network of 15-passenger transit vans for about $5 per person on average, thus enhancing the transportation experience while reducing unnecessary vehicles off of the roads.
Remento — A science-backed app to capture family stories through conversation.
Duzter Hockey — Duzter offers a wide range of cut resistant hockey protective equipment to keep players safe on the ice. We have everything you need to stay protected while training or playing.

Investing in the Near Frontier

Investment focus

Biotechnology, Software, Health Care
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

SoloPulse — SoloPulse is changing how the world sees by bringing a new approach to sensing and communication technologies that is based on proprietary mathematical wave theory algorithms. This approach unlocks barriers that legacy technologies face while also improving computational efficiency and resolution. SoloPulse’s advanced sensing and beamformingtechniques can use a single electromagnetic pulse to produce high-resolution imaging and increased data transmission rates.
Castelion — We are a modern defense production company building the next generation of military hypersonic, vehicle, and strike systems to deter future wars.
Salient Motion — A next-generation supplier for aerospace and defense, specializing in advanced electric propulsion.

Early-stage venture capital fund focused on investments in technology companies within the supply chain, manufacturing and digital industrial sectors

Investment focus

Software, Logistics, Supply Chain Management
Seed, Series A, Pre-Seed
United States

Portfolio highlights

Wilya — Reimagine the future of Industrial Work. ; Unlock Talent Pools. Millions of people are not able to work 8 hours a day or 5 days a week. ; Increase Diversity. Gig and Take helps you create and mange a flexible workforce.
Harbinger — Founded by veterans of Canoo and Faraday Future, Harbinger is an automotive company that develops EV platforms optimized for medium-duty trucks and delivery vans.
Reshape Automation — AI-powered industrial automation marketplace and platform that simplifies the discovery, design, deployment, and support of automation

A successful serial entrepreneur and early defense tech investor, Jackson Moses currently serves as the Founder and Managing Partner of Silent Ventures, an early stage venture firm that invests in exceptional founders building unrivaled aerospace, defense, and national security startups. He also founded and manages Silent Capital, a privatesyndicate that provides its members exclusive access to leading multi-stage defense and deep tech deals. Additionally, Jackson serves as a Senior Advisor to the founding teams of Castelion and Privateer Space.Prior to founding Silent Ventures, Jackson founded and served as VP of Partnerships at MainStreet: the first tech company to make R&D tax credits accessible to startups and SMBs via industry-leading workflows and integrations. As a founding executive, he was responsible for developing go-to-market strategies, building a world-class sales organization, managing business development initiatives, and scaling annual revenue to over $30M. To date, MainStreet has employed hundreds of people and helped 2,000+ startups claim over $150M in tax savings, collectively extending their runway by centuries.Prior to founding MainStreet, Jackson founded and served as Chairman & CEO of Spectrum Labs (enterprise AIaaS), which was acquired by ActiveFence after last being valued at $137M. Spectrum Labs pioneered multimodal LLMs, specifically a series of proprietary GPT foundation models, designed to make digital communities more profitable for Fortune 500 owners, marketers, influencers, and their users. Its customer base spanned gaming, dating, and social media, and included Tencent (TCEHY), Pinterest (NYSE: PINS), Grindr (NYSE: GRND), Yik Yak, Wildlife Studios, and The Meet Group, among others.Prior to founding Spectrum Labs, Jackson worked in sales (Lynda.com), customer operations, and executive recruiting at LinkedIn (acquired by Microsoft). Prior to this, he worked as a Market Research Analyst at Cisco where he evaluated industry trends, new investment opportunities, and emerging threats to Cisco’s core business lines.Having raised $120M+ across his two companies, Jackson actively advises startups, venture firms, and family offices on private sector aerospace and defense tech trends, investment opportunities, and capital allocation strategies. He serves as a Venture Partner to several large firms and has sourced deals for 8VC, Founders Fund, a16z, Lightspeed, Airbus Ventures, Quiet Capital, Susa Ventures, family offices, defense primes, and university endowments.Jackson holds two B.A. degrees from the University of California, Berkeley where he studied Economics, with a concentration in monetary policy, and Political Science, with a concentration in game theory.

Investment focus

Aerospace, National Security, Artificial Intelligence
Pre-Seed, Seed, Series A
United States

Portfolio highlights

Starfish Space — Starfish Space: We're developing the first on-demand fleet of versatile and efficient space tugs prepared to service on-orbit satellites. --- Active life extension, debris removal, autonomous transportation
Deterrence — Deterrence is a defense technology company focused on automating the production of reliable, safe energetics at scale.
Allen Control Systems — Allen Control Systems is a robotics defense company purpose-built to deliver advanced robotic capabilities to fill modernization demands across the defense industry and national security communities.

Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs to build innovative consumer, enterprise, and healthcare technology companies.

Investment focus

Software, Internet, Mobile
Series B, Series A, Series C
United States, India, Canada

Portfolio highlights

Numa — Turns BDCs and Advisors into world-class communicators, using visibility + accountability + a healthy dose of AI superpowers
Numa — Leverage modern Generative-AI to autonomously capture every RO, schedule service appointments, and deliver service updates in real time.
VideaHealth — Transforming Dentistry Through AI. By applying AI to X-ray analysis, we unlock insights, experiences, and efficiencies that drive breakthroughs in clinical outcomes and economics for dentists and insurers.

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

Investment focus

Health Care, Information Technology, Biotechnology
Seed, Series A, Convertible Note
United States, France, Israel

Portfolio highlights

Liminal — Advanced battery inspection and metrology with ultrasound and machine learning
Aralez Bio — Aromatic noncanonical amino acids that are made using biocatalysis. Single step, enzyme synthesis makes hundreds of tryptophan and other amino acid analogs!
AdipoPharma — By harnessing the power of the Adipocyte AdipoPharma is committed to developing innovative treatment for type 2 diabetes

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Pre-Seed
United States, Mexico, Canada

Portfolio highlights

Superlogic — OneOf is the mass-consumer Web3 company connecting the next 100M non-crypto-native fans to iconic brands, artists, and athletes. OneOf technology enables global brands and enterprises to reimagine commerce, loyalty and engagement, allowing consumers to seamlessly collect or trade digital assets with no prior crypto expertise. Deeply committed to a sustainable and inclusive blockchain future, minting digital assets on OneOf's platform uses up to 2 million times less energy than previous generation proof-of-work networks, and costs up to 99% less in gas fees. A leader in diversity, over 80% of the collections curated by OneOf come from minority or female creators.
Patlytics — Patent discovery, analytics, comparison, and workflow. Simplified via Artificial Intelligence.
Stepchange — Better, faster data and data infrastructure.

We are deep tech venture capital.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Lumafield — Lumafield's easy-to-use CT scanner and cloud-based software give engineers the ability to see their work clearly, inside and out.
Fervo Energy — Fervo Energy delivers 24/7 carbon-free energy through development of next-generation geothermal projects.
Alta Resource Technologies — Alta Resource Technologies is on a mission to reinvent mining by harnessing advanced biochemistry to cost-effectively source the critical raw materials needed to power next-generation technology and bolster economic security. Our groundbreaking technology platform leverages customizable proteins to separate high-purity rare earth elements and otheressential minerals with unprecedented selectivity while dramatically reducing the environmental impact of mining.

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

Investment focus

Software, FinTech, Information Technology
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Cryptio — We offer enterprise-grade accounting, reporting, and audit software for your digital assets.
Maestro — Advanced UTxO-indexing data layer to supercharge Defi on Bitcoin, Cardano & Dogecoin.
The Open Network Foundation — A decentralized and open internet designed to onboard 500M people on-chain, built by the community using technology developed by Telegram.

Investing catalytic capital in promising seed stage companies located outside of Silicon Valley, NYC & Boston. Backed by a group of iconic entrepreneurs, executives & investors.

Investment focus

Software, SaaS, Information Technology
Seed, Series A, Funding Round
United States, Canada, Argentina

Portfolio highlights

Knit — Knit helps researchers run agency-quality quant + qual research at DIY costs, by taking the most time-intensive research tasks off their plate through Researcher-Driven AI.
Cambium Carbon — Saving wood to save the planet. By revolutionizing supply chains, we introduce the world's first carbon smart material.
Gig Wage — Instant payouts for 1099 contractors and easy contractor payroll. 1099 Payments & Payroll APIs. Stay compliant with Gig Wage. Sign up free.

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

Investment focus

Software, Health Care, Internet
Seed, Series A, Series B
United States, France, Mexico

Portfolio highlights

And AI — Professional-Grade AI for Patent Attorneys. AI for end-to-end prosecution and litigation workflows in one secure, collaborative workspace. Accelerate prior art search, claim chart drafting, and more.
Gigs — Gigs is building Stripe for SIM cards. Providing platforms custom phone & data plans through an easy to use API in 180+ countries.
Prima — Reliable manufacturing & supply chain partner for custom parts, metal fabrication & efficient sourcing from Mexico. Manage design, production & delivery

Ben Franklin helps early-stage technology companies and established manufacturers translate innovation into commercial success and economic prosperity.

Investment focus

Manufacturing, Health Care, Software
Grant, Seed, Debt Financing
United States, United Kingdom, Brazil

Portfolio highlights

Venseca — Venseca is a global leader in digital trust. Our patent-pending solution generates Digital Trust Scores and comprehensive, independently validated reports to help you understand the cyber risk profile of all of your suppliers.
UnityLab — Welcome to UnityLab, home of the best small business & brand builders dedicated to business technology, operations, finance, & sales tools.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

VEIR — Discover VEIR's cutting-edge technology for superconducting power lines that offer 5-10x greater transfer capacity and 90% less resistive line losses.
Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

CO/AI — CO/AI is a community focused on fostering expertise and skills in artificial intelligence (AI) among individuals and businesses. This initiative aims to prepare participants for success in an increasingly AI-driven economy through various educational and collaborative efforts.
1up — 1up is a competitive AI for users to observe and understand everything their competitors are doing. 1up accelerates and automates the competitive experience for teams. 1up enables teams to save hours of manual effort in product, sales, and marketing, understand what their competitors are building and saying, and win competitive deals faster andeasier than ever before.
Utila — Securely manage, build, and scale your institutional digital asset operations with Utila's MPC-powered platform. Leverage unparalleled security, robust governance and countless ecosystem integrations.

Bolt: Investing at the intersection of the digital and physical worlds

Investment focus

Software, Health Care, Hardware
Seed, Pre-Seed, Series A
United States, Canada

Portfolio highlights

FYTO — Revolutionary Sustainable Agriculture
Blackbird — We believe the next great hospitality technology platform should connect restaurants and their customers directly, in meaningful and ongoing ways. Blackbird is founded by a team with a passion for restaurants and a track record of using technology to solve problems.
Foundation — Self custody is finally attainable. Secure your Bitcoin with an unprecedented combination of elegance and ease of use.

Propel(x) is where investors discover, evaluate and invest in technology startups and venture capital funds.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Series B
United States, Canada, Singapore

Portfolio highlights

Healx — At Healx we use AI drug discovery to develop new treatments for rare diseases. We bring treatments from prediction to patient.
AMPRION — Amprion is a biotech company that focuses on the diagnosis of brain diseases like Parkinson’s, Alzheimer’s, and Lewy Body Dementia. The company was founded in 2007 and is headquartered in San Francisco, California, United States.
Motion Gestures — Motion Gestures is a Canadian machine learning startup specializing in gesture recognition software. Motion Gestures specializes in machine learning-based gesture recognition software and was founded in Waterloo, Canada in 2016. The company aims to enable the rapid development and deployment of gesture-enabled interfaces for systems, devices, andapps. Its software supports advanced 2D and 3D gestures using motion, touch, and vision sensors and can be deployed on the cloud, gateway/hub, and embedded platforms. Developers are offered free licenses to the cloud SDK and can quickly create and test any gesture using their smartphones.

Lerer Hippeau is an early-stage venture capital fund based in New York City. As founders and operators ourselves, we see returns in relationships

Investment focus

Software, E-Commerce, Internet
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Air — Do you like your marketing and brand collateral scattered everywhere? Neither do we. Send productivity soaring with a flexible and powerful creative ops system.
Teal — Free tools and resources to run a faster and better job search so you can focus your time and energy on finding and landing a job you will love.
Urban Sky — Urban Sky is developing the first-ever reusable 'micro-sat' version of a near-space balloon, armed with sensors that collect high-value Earth observation data over entire cities, serving a multi-billion dollar imagery market and making daily and weekly aerial imagery collection a cost-effective reality. Leveraging advances in componentminiaturization, first-of-its-kind balloon reusability, and the high vantage point of the stratosphere, the Microballoon drastically reduces the cost of high-resolution remote sensing and weather-related data capture over broad areas, leading to more impactful data over more areas than ever before.With a new wealth of data from the stratosphere - this completely untapped layer of Earth’s atmosphere - we can fundamentally change the collective human understanding of the surface of our planet and urban centers.

CEVG is an angel investor collective that invest in and mentors early-stage cleantech and climatetech startups across North America.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Seed, Funding Round
United States, Canada

Portfolio highlights

PeakSyncer — PeakSyncer, a product of Zhong Xi Group, LLC, is an AI-powered cloud platform that offers a comprehensive solution for utilities aiming to optimize their energy management systems through advanced technology. The platform focuses on demand response programs, utilizing artificial intelligence to automate and streamline the management of peak energyloads. PeakSyncer has focused on creating cutting-edge solutions in cloud computing and AI integration. The company positions itself as a leader in the energy management sector, working on delivering reliable, user-friendly solutions that adapt to the evolving needs of energy grids. With dedicated support and 24/7 monitoring, PeakSyncer aims to empower utilities to modernize their operations and optimize resource usage effectively.With PeakSyncer, the company addresses a critical business need for seamless data synchronization across platforms such as ERP, CRM, and other essential business software. The platform’s key advantage is its ability to adapt to dynamic data patterns, learning from past syncs to continuously improve syncing accuracy and efficiency.PeakSyncer is designed to be scalable and easily integrates with existing utility infrastructure, ensuring a smooth implementation process. The platform not only helps utilities meet regulatory requirements but also supports them in creating a sustainable energy ecosystem by engaging customers in demand response initiatives, made possible by AI algorithms that analyze and anticipate potential data issues before they disrupt business processes.
Cala Systems — Discover Cala, the innovative heat pump water heater that customizes heating to your lifestyle. Save money, reduce your carbon footprint, and enjoy easy installation with Cala. Reserve yours today and experience efficient, eco-friendly hot water tailored to your needs.
Electrified Thermal Solutions — Electrified Thermal Solutions, Inc. is developing the Joule Hive: a new energy storage technology that converts surplus zero-carbon electricity into heat.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

Flock Safety — From creating safer neighborhoods to protecting employees and property, we help you deter and solve crime with tools customized and scaled to your needs.
Rune Technologies — Rune Technologies' objective is to consistently deliver innovative logistics technology to support the free world's enduring values, enable quick triumphs, and maintain peace through strength.
Mercury — Powerful banking. Simplified finances. Apply in 10 minutes for business banking that transforms how you operate.

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

Investment focus

Software, Health Care, Information Technology
Series B, Series C, Series A
United States, Israel, Canada

Portfolio highlights

Quantifind — Risk screening & investigations, supercharged by science.
Stream Security — Empowering organizations to code and deploy configurations faster and safer, from plan to production.
Okami Medical — Okami Medical develops and commercializes new devices for the treatment of heart disease. It was formed to address the evolving needs of patients and physicians through the development of innovative, versatile, and intuitive medical devices for the occlusion of peripheral vessels. Okami believes that vessel occlusion should be rapid and reliableregardless of tortuosity and flow conditions. The LOBO Vascular Occlusion System was developed for this reason.It was founded in 2011 and is headquartered in Aliso Viejo, California.

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