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Top 50 Life Science Startup Investors in United States in November 2024

A list of 50 angel investors and VC (Venture Capital) funds that invest in Life science startups based in United states. We rank investors based on the number of investments they made in Life science companies from United states. We update this investor list every month.

Top 50 Life Science Startup Investors in United States in November 2024

Investor Life Science United States investments
ARCH Venture Partners 24
SOSV 21
Alexandria Venture Investments 19
Northpond Ventures 19
Novartis Venture Fund 14
RA Capital Management 13
Third Rock Ventures 12
Atlas Venture 12
DCVC 12
Hatteras Venture Partners 11
8VC 11
Civilization Ventures 11
Fifty Years 11
Alix Ventures 10
5AM Ventures 10
MPM Capital 10
OrbiMed 10
Andreessen Horowitz 10
Sahsen Ventures 10
Rev1 Ventures 9
Longwood Fund 9
SR One 9
KdT Ventures 9
Versant Ventures 9
Google Ventures 9
Cormorant Asset Management 8
Apple Tree Partners 8
Playground Global 8
New Enterprise Associates 8
The Column Group 8
Lux Capital 8
Vivo Capital 8
iSelect Fund 8
Breakout Ventures 7
Roche Venture Fund 7
Flagship Pioneering 7
Horizons Ventures 7
Foresite Capital 7
Dolby Family Ventures 7
Connecticut Innovations 7
Illumina Ventures 7
Pear VC 7
Artis Ventures (AV) 7
JDRF T1D Fund 6
Khosla Ventures 6
Digitalis Ventures 6
venBio Partners 6
Refactor 6
Felicis 6
Catalio Capital Management 6
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Investor list
ARCH Venture Partners VC Fund · Chicago, Illinois, United States · 24 investments in the past 12 months
ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, China, United Kingdom
Portfolio highlights
  • Vizgen — The next generation of genomics, expanding the impact of spatial context and demonstrating the potential of in situ single-cell spatial genomics.
  • Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
  • Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.
SOSV VC Fund · Princeton, New Jersey, United States · 75 investments in the past 12 months
SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.
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Investment focus
  • Biotechnology, Health Care, Software
  • Seed, Convertible Note, Pre-Seed
  • United States, India, United Kingdom
Portfolio highlights
  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
Alexandria Venture Investments VC Fund · Pasadena, California, United States · 19 investments in the past 12 months
Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, Canada, France
Portfolio highlights
  • CrossBridge Bio — CrossBridge Bio operates as a biotechnology company, innovates ADC therapeutics through stable dual linker payload technology.
  • Leal Therapeutics — Leal Therapeutics develops novel therapeutics for patients.
  • Archon Biosciences — Archon is a biotechnology firm that creates computationally engineered proteins to unleash potent therapeutic targets beyond the grasp of current methods and improve disease management.
Northpond Ventures VC Fund · Bethesda, Maryland, United States · 10 investments in the past 12 months
Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow. Our investments are focused on life sciences, technology, and affiliated industries.
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Investment focus
  • Biotechnology, Health Care, Life Science
  • Series A, Series B, Series C
  • United States, United Kingdom, Canada
Portfolio highlights
  • Vizgen — The next generation of genomics, expanding the impact of spatial context and demonstrating the potential of in situ single-cell spatial genomics.
  • VieCure — The VieCure platform is an Clinical Decision Support solution in Oncology that combines the power of artificial intelligence, codified clinical rules and pathways, precision oncology, telehealth, smartphone technology, and the EMR to transform cancer care.
  • Inflammatix — Inflammatix develops rapid point of care diagnostic tests by reading the immune system, and resolves major clinical health challenges.
Novartis Venture Fund VC Fund · Basel, Basel-Stadt, Switzerland · 2 investments in the past 12 months
Learn about the approach the Novartis Venture Fund takes to investing in innovative life science companies developing biotechnology and biopharmaceutical therapeutics that address unmet patient needs.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series B, Series A, Series C
  • United States, Switzerland, United Kingdom
Portfolio highlights
  • Hyku — Hyku Biosciences is developing the next generation of covalent medicines by targeting histidine, tyrosine and lysine binding pockets in disease-causing proteins.
  • Exsilio Therapeutics — Exsilio's method is based on naturally occurring genetic elements that can accurately insert new genes into cells via RNA intermediate templates. Exsilio employs predictive in-silico modeling and wet lab-based experiments to create such elements for accurate insertion of therapeutic genes into safe harbor regions of disease-relevant cells.
  • Enterprise Therapeutics — Enterprise Therapeutics is a drug discovery company dedicated to the researchand development of novel therapies for the treatment of respiratory diseases.In diseases such as cystic fibrosis, asthma and COPD the lungs become congested with mucus leading to difficulty in breathing. New disease modifying therapies that target the underlyingmechanisms of mucus congestion will reduce the frequency of lung infections and improve patient quality of life.
RA Capital Management VC Fund · Boston, Massachusetts, United States · 60 investments in the past 12 months
RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series B, Series C, Series A
  • United States, United Kingdom, Canada
Portfolio highlights
  • Monopar — Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.Its lead compound, Hu-ATN-658, is a novel monoclonal antibody for the potential treatment of several deadly cancers. Hu-ATN-658 targets the urokinase plasminogen activator receptor (uPAR). Cancer Research UK will be conductingHu-ATN-658’s early development, including a Phase I clinical trial.In 2014, Chandler D. Robinson, Christopher M. Starr, and Andrew P. Mazar founded the company in Wilmette, Illinois.
  • Evommune — Evommune is taking a tissue-based approach to advance insights and accelerate the development of transformative medicines in inflammatory diseases.
  • Eledon Pharmaceuticals — Eledon Pharmaceuticals, Inc. is a clinical-stage biotechnology company using its expertise in targeting the CD40L pathway to develop potential treatments for people undergoing organ or cellular transplantation, and for people with autoimmune and neurodegenerative disease.
Third Rock Ventures VC Fund · Boston, Massachusetts, United States · 4 investments in the past 12 months
Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States
Portfolio highlights
  • Marea Therapeutics — Marea Therapeutics is a clinical-stage biotechnology firm that uses the most recent advancements in human genetics to create first-in-class, next-generation medications for cardiometabolic illnesses.
  • Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
  • Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.
Atlas Venture VC Fund · Cambridge, Massachusetts, United States · 16 investments in the past 12 months
Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, United Kingdom, Canada
Portfolio highlights
  • Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
  • Triveni Bio — Triveni Bio is at the forefront of human genetics, cutting-edge antibody design, and precision medicine, pioneering the identification of new disease targets.
  • Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
DCVC VC Fund · San Francisco, California, United States · 20 investments in the past 12 months
We are deep tech venture capital.
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Investment focus
  • Software, Artificial Intelligence, Health Care
  • Seed, Series A, Series B
  • United States, Canada, United Kingdom
Portfolio highlights
  • Q-CTRL — Infrastructure software to power the quantum future
  • Reality Defender — Reality Defender is deepfake detection done right. With billions of visual and audio assets indexed, we offer the most robust deepfake detection available.
  • Impulse Space — Economical and nimble last-mile space payload delivery
Hatteras Venture Partners VC Fund · Durham, North Carolina, United States · 2 investments in the past 12 months
Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series A, Series B, Funding Round
  • United States, Canada
Portfolio highlights
  • Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
  • AtaCor Medical — AtaCor Medical - Designing innovative solutions to deliver temporary, interim, and permanent cardiac pacing when, and where it matters most.
  • Veralox Therapeutics — Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes. Based on an understanding of the molecular mechanisms of these diseases, these efforts will lead to new treatment paradigms and better outcomes for patients.
8VC VC Fund · San Francisco, California, United States · 40 investments in the past 12 months
8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.
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Investment focus
  • Software, Health Care, Artificial Intelligence
  • Seed, Series A, Series B
  • United States, Canada, United Kingdom
Portfolio highlights
  • Boardy — Join hundreds of humans on the boardy network
  • Hello Patient — Healthcare AI that gets your team off the phone & in front of patients
  • Parallel Fluidics — Custom microfluidic devices in 3 days.
Civilization Ventures VC Fund · San Francisco, California, United States · 10 investments in the past 12 months
DIGITAL HEALTH / AI DIGITAL HEALTH / AI GENE / CELL THERAPIES NASDAQ: RCKT GENE / CELL THERAPIES NASDAQ: RCKT GENOMICS / DIAGNOSTICS GENOMICS / DIAGNOSTICS SYNTHETIC
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Investment focus
  • Biotechnology, Health Care, Medical
  • Seed, Series A, Series B
  • United States, United Kingdom, Brazil
Portfolio highlights
  • SyntaxBio — SyntaxBio develops CRISPR/Cas9-based, genetic programming platform that converts cells into biological computers using DNA-based instructions that read like lines of code. SyntaxBio's platform can program cells without the need for consistent external intervention.
  • Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
  • Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.
Fifty Years VC Fund · San Francisco, California, United States · 10 investments in the past 12 months
WE BACK HEROES using technology to solve the world's biggest problems
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Investment focus
  • Biotechnology, Health Care, Medical
  • Seed, Series A, Series B
  • United States, Germany, Canada
Portfolio highlights
  • Aalo Atomics — Creating abundant and dependable clean energy to power humanity for generations.
  • BillionToOne — We are a team at the forefront of disease detection focused on moving Prenatal Screening and Liquid Biopsy forward.
  • Waypoint Bio — Waypoint's proprietary spatial multi-omics platform enables us to solve critical issues around understanding how cell therapies navigate the three-dimensional tumor microenvironment and allow the measurement of cell-to-cell interactions.
Alix Ventures VC Fund · San Francisco, California, United States · 2 investments in the past 12 months
Supporting early stage Life Science startups driving patient impact. Born from our collective experience as founders, we set out to build the fund we wanted to raise from....
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Investment focus
  • Biotechnology, Health Care, Life Science
  • Seed, Series A, Pre-Seed
  • United States
Portfolio highlights
  • Xilis — Xilis is an oncology and precision health company that diagnoses cancer and finds the right treatment. The company uses “micro-organoids” to make thousands of 3D replicas of a patient’s tumor in about six days, which the company says can be used for testing for drug compatibility faster. It was founded in 2019 and is headquartered in Durham,North Carolina.
  • Elegen — Elegen is powering the bioeconomy with high-accuracy DNA synthesis that delivers industry-leading speed, length, and quality.
  • Zafrens — Zafrens specializes in developing tools and generating insights at the interface of biology, chemistry, and engineering. The company was founded in 2021 and is headquartered in San Diego, California, United States.
5AM Ventures VC Fund · Menlo Park, California, United States · 8 investments in the past 12 months
5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, Switzerland, United Kingdom
Portfolio highlights
  • RareCyte — Rarecyte provides precision medicine solutions focused on multiplexed analysis of cells and tissue with applications in both research and clinical diagnostics.
  • TMRW Life Sciences — TMRW helps patients and clinics safely store their eggs and embryos
  • Tectonic Therapeutic — Tectonic and AVROBIO have completed their anticipated merger.Please follow this link to our press release for additional information.
MPM Capital VC Fund · Cambridge, Massachusetts, United States · 2 investments in the past 12 months
Powering Breakthroughs in Life Sciences
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Investment focus
  • Biotechnology, Health Care, Pharmaceutical
  • Series B, Series A, Series C
  • United States, United Kingdom, Canada
Portfolio highlights
  • AstronauTx — AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.
  • Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
  • Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies
OrbiMed VC Fund · New York, New York, United States · 43 investments in the past 12 months
Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series B, Series A, Series C
  • United States, China, Israel
Portfolio highlights
  • enGene — enGene is a developer of a mucosal immunotherapy platform designed to treat inflammatory bowel disease and diabetes. The company's mucosal immunotherapy platform has developed a flexible nucleotide delivery technology targeting mucosal tissues to treat numerous prevalent, chronic diseases via the induction or suppression of protein expressionlevels, enabling physicians and doctors to regenerate physiologic, meal-regulated insulin secretion from the gut of subjects with diabetes.
  • Leal Therapeutics — Leal Therapeutics develops novel therapeutics for patients.
  • Lomond Therapeutics — Lomond Therapeutics is a pharmaceutical firm that discovers and develops small molecule inhibitors that target escape variants in hematologic malignancies.
Andreessen Horowitz VC Fund · Menlo Park, California, United States · 124 investments in the past 12 months
Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.
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Investment focus
  • Software, Information Technology, Internet
  • Series A, Seed, Series B
  • United States, United Kingdom, Canada
Portfolio highlights
  • Infinitus Systems — Infinitus Systems offers Voice Robotic Process Automation (VoiceRPA) software for businesses in the healthcare industry.
  • Valon Technologies — Valon Mortgage is a Fannie Mae and Freddie Mac approved, tech-enabled residential mortgage servicer. The company’s mission is to champion homeowners on their financial journey as the partner they trust with their home and their future.
  • Infinite Machine — Infinite Machine is to create the world's most captivating non-auto vehicles. Infinite Machine initial product, the P1, is a revolutionary new personal electric vehicle that combines innovative performance and usefulness with an industrial-style look. In Infinite Machine's ideal post-car future, environment and people coexist together.
Sahsen Ventures VC Fund · Seattle, Washington, United States · 4 investments in the past 12 months
Sahsen Ventures is a venture capital firm making investments in for-profit and nonprofit organizations with an emphasis on technology and biotechnology. It was established in 2016 and is based in Seattle, Washington.
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Investment focus
  • Biotechnology, Health Care, Non Profit
  • Funding Round, Series A, Seed
  • United States, China, Ghana
Portfolio highlights
  • Insamo — Insamo is a global biotechnology company pioneering the discovery of membrane-permeable and orally available cyclic-peptides with antibody-like binding affinity.
  • Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
  • Archon Biosciences — Archon is a biotechnology firm that creates computationally engineered proteins to unleash potent therapeutic targets beyond the grasp of current methods and improve disease management.
Rev1 Ventures VC Fund · Columbus, Ohio, United States · 9 investments in the past 12 months
Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!
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Investment focus
  • Software, Health Care, Information Technology
  • Seed, Series A, Funding Round
  • United States, Germany
Portfolio highlights
  • HubiFi — SaaS Financial Automation & Analysis for High Transaction Businesses
  • Myoptechs — Myoptechs, a pediatric ophthalmic medical device startup in the clinical stage, has made advancements in its fund-raising and clinical research program. The company creates innovative soft contact lenses and spectacles that reduce the growth of myopia while offering incredibly clear vision.
  • Power to Hydrogen — Power to Hydrogen (P2H2) is simplifying hydrogen. Our technology enables a brighter energy future by solving the technical and economic challenges that come with producing hydrogen. Our AEM-based, electrolysis technology produces high pressure, high efficiency hydrogen from renewable energy with lower cost materials thancompeting electrolyzers. This technology can reduce the total cost of hydrogen to enable clean transportation, store energy efficiently, and decarbonize industrial processes. In addition to low-cost, high-pressure hydrogen production, the technology can produce high-pressure oxygen and be used reversibly to produce electricity. Both services can create additional revenue streams to make the total cost of hydrogen $1/kg.
Longwood Fund VC Fund · Boston, Massachusetts, United States · 7 investments in the past 12 months
Longwood creates and invests in science-based companies that develop novel solutions for important medical problems
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Investment focus
  • Biotechnology, Therapeutics, Health Care
  • Series A, Series B, Series C
  • United States, United Kingdom, Italy
Portfolio highlights
  • Evommune — Evommune is taking a tissue-based approach to advance insights and accelerate the development of transformative medicines in inflammatory diseases.
  • Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
  • Progentos Therapeutics — Progentos Therapeutics develops an approach to treat multiple sclerosis that stimulates the body's natural repair mechanisms.
SR One VC Fund · Cambridge, Massachusetts, United States · 6 investments in the past 12 months
SR One Capital Management is a leading trans-Atlantic biotech venture capital firm that partners with top entrepreneurs, scientists and investment partners to seek to build elite biotechnology companies. Our mission is to translate ground-breaking technologies into next generation medicines to benef
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, United Kingdom, Canada
Portfolio highlights
  • Asceneuron — Asceneuron develops effective therapeutics for orphan tauopathies and Alzheimer’s disease. By focusing on areas of high unmet medical need, Asceneuron aspires to become a leading biotech company specialized in small molecule drug discovery for neurodegenerative diseases.Tauopathies are currently untreatable neurodegenerative diseases thatrapidly progress towards debilitating conditions. The appearance of deposits of the microtubule-associated tau protein as e.g. neurofibrillary tangles in neurons of the brain is a common feature of tauopathies that is shared with Alzheimer’s disease. Neuronal tau deposits are known to be a major contributor to neurodegeneration and mutations in the tau gene are causative of the tauopathy fronto-temporal dementia and parkinsonism linked to chromosome 17 (FTDP-17).Due to increasing life expectancy, Alzheimer’s disease is viewed as one of the largest healthcare problems of this century, imposing a major economic burden on societies in the Western and developing world. Current treatment options provide limited benefits supporting the urgent need for more efficacious and better tolerated medicines that address symptomatic relief as well as disease progression.
  • Renalys Pharma — Renalys Pharma is a private, late-stage clinical biopharmaceutical firm in Japan dedicated on developing new therapies that address unmet needs in the management of renal illness in Japanese and Asian patients.
  • Nomic — Nomic develops a proteomic technology platform designed to understand, detect, and treat diseases with DNA nanotechnology. NPlex's platform and research provides cost-effective measurement of protein data with sample, fits seamlessly within industry cytometers for high-throughput analysis, and development of custom protein panels.It allowsnanotechnology developers and businesses to bring improvement in existing instrument, workflow, and bring automation in the system.
KdT Ventures VC Fund · Austin, Texas, United States · 8 investments in the past 12 months
KdT Ventures is the standard for early-stage frontier science investing.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Seed, Series A, Series B
  • United States, Israel, Germany
Portfolio highlights
  • Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
  • March Biosciences — Transforming Patient Care by Unlocking New Target Spaces March Biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity
  • Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases
Versant Ventures VC Fund · Menlo Park, California, United States · 8 investments in the past 12 months
Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series A, Series B, Series C
  • United States, Switzerland, Canada
Portfolio highlights
  • 858 Therapeutics — 858 Therapeutics is a stealth company specializing in the area of healthcare services, pharmaceutical, and biotechnology. The company was founded in 2019 and is headquartered in San Diego, California, USA.
  • Borealis Biosciences — Borealis Biosciences was founded on the premise that a convergence of scientific and translational breakthroughs is enabling the field of RNA medicines to treat kidney diseases and beyond. The company is backed by founding investor Versant Ventures and Novartis AG, and has a strategic collaboration with the pharma.
  • Bright Peak Therapeutics — Bright Peak is a biotech company that develops a portfolio of immunotherapies for the treatment of cancer and autoimmune diseases. At Bright Peak, they are creating innovative cytokine therapeutics that are uniquely engineered to precisely control and expand desired biological properties.
Google Ventures VC Fund · Mountain View, California, United States · 64 investments in the past 12 months
GV supports innovative founders moving the world forward.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series A, Series B, Seed
  • United States, United Kingdom, Switzerland
Portfolio highlights
  • Infinitus Systems — Infinitus Systems offers Voice Robotic Process Automation (VoiceRPA) software for businesses in the healthcare industry.
  • Speakeasy — Create great integration experiences for your APIs: native-language SDKs, Terraform providers, and friction-free docs.
  • PeopleOne Health — PeopleOne Health provides world-class healthcare that seamlessly blends treatment and prevention, leading to significant savings for employers and employees by keeping people healthier. This is the next generation of value-based primary care. Employers save up to 30% on healthcare costs and enhance employee recruiting and retention. Employees getaccess to an award-winning health benefit at no cost, including a team of top-tier doctors and healthcare professionals. Leading employers and thousands of members trust PeopleOne Health and rate their customer satisfaction an excellent 90+ NPS (exceeding the healthcare industry average of 35). Discover more at peopleonehealth.com.
Cormorant Asset Management VC Fund · Boston, Massachusetts, United States · 15 investments in the past 12 months
Cormorant Asset Management is an employee-owned hedge fund sponsor that provides its services to pooled investment vehicles. The firm also focuses on both public and private market innovative companies in the biotechnology and life sciences marketplace.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series B, Series A, Series C
  • United States, China, Switzerland
Portfolio highlights
  • enGene — enGene is a developer of a mucosal immunotherapy platform designed to treat inflammatory bowel disease and diabetes. The company's mucosal immunotherapy platform has developed a flexible nucleotide delivery technology targeting mucosal tissues to treat numerous prevalent, chronic diseases via the induction or suppression of protein expressionlevels, enabling physicians and doctors to regenerate physiologic, meal-regulated insulin secretion from the gut of subjects with diabetes.
  • OnKure Therapeutics — OnKure Therapeutics - Writing the Next Chapter in Precision Medicines for Patients With Cancer
  • Axonis Therapeutics — AXONIS Therapeutics, Inc. is advancing breakthrough discoveries to develop first-in-class therapies for neurological disorders.
Apple Tree Partners VC Fund · New York, New York, United States · 2 investments in the past 12 months
ATP, a global leader in life sciences venture capital, is developing the next generation of transformative biotechnology companies. ATP creates science-based companies starting with assets at various stages: from working with scientists on pre-IP ideas, to spinouts from existing company pipelines. The firm provides flexible capital, strategicinsight, and operational resources to build sustainable, research-driven enterprises. ATP invests in its portfolio companies from seed stage through IPO and beyond and supports their management teams in strategic transactions and synergistic business combinations.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Seed
  • United States, Canada, United Kingdom
Portfolio highlights
  • Ascidian Therapeutics — Ascidian Therapeutics is a biotechnology company intended for medical use in medical and clinical gene therapy.
  • Red Queen Therapeutics — Staying ahead of viral threats with new innovations in antiviral therapy
  • Deep Apple Therapeutics — Deep Apple Therapeutics is discovering new small-molecule therapeutics with unprecedented speed and exceptional acumen.
Playground Global VC Fund · Palo Alto, California, United States · 4 investments in the past 12 months
Playground is an early-stage investment firm that helps old and new investors and entrepreneurs working at the intersection of bits, atoms, and AI. It focuses on investment, innovation, connected hardware, artificial intelligence, and robotics.
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Investment focus
  • Software, Robotics, Artificial Intelligence
  • Series A, Seed, Series B
  • United States, Canada, France
Portfolio highlights
  • Anjuna — Anjuna confidential cloud software establishes a secure enclave that isolates and encrypts applications and data in runtime, at rest, and on the network for end-to-end data protection
  • Insamo — Insamo is a global biotechnology company pioneering the discovery of membrane-permeable and orally available cyclic-peptides with antibody-like binding affinity.
  • Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
New Enterprise Associates VC Fund · Menlo Park, California, United States · 42 investments in the past 12 months
Foundational partners to ambitious founders at every stage of company-building.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series B, Series A, Series C
  • United States, India, China
Portfolio highlights
  • Sana — Sana is an AI company building the next generation of knowledge tools. Designed and engineered in Stockholm, Sweden.
  • Outrider — Autonomous yard operations have set a new standard. Yard automation transforms yard operations into an efficient, safe, and sustainable solution.
  • Pathos — Pathos is a clinical-stage biotechnology company focused on re-engineering drug development with the power of advanced AI technologies.
The Column Group VC Fund · San Francisco, California, United States · 14 investments in the past 12 months
The Column Group is a venture capital firm dedicated to creating the next generation of biotechnology companies. They manage over $4 billion in assets and focus on building companies with groundbreaking scientific platforms that have the potential to deliver significant new therapies for unmet medical needs. TCG takes a long-term approach, aimingto develop companies capable of generating multiple product opportunities rather than focusing on quick exits.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States
Portfolio highlights
  • Nura Bio — Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders.
  • Circle Pharma — Circle Pharma is an early-stage biotechnology company applying proprietary computational design algorithms and innovative chemistry to develop cell-permeable macrocycle peptide therapeutics against important clinical targets. It does this through an iterative, rational design process that deploys large virtual libraries of conformationally diversemacrocycle scaffolds selected for inherent permeability. The company was founded by Matt Jacobson and Scott Lokey in 2012 and is headed by David J. Earp.
  • NGM Biopharmaceuticals — Our broad, diverse pipeline of novel, first-in-class medicines spans multiple therapeutic areas and diseases. Every program focuses on a large market indication with high unmet needs and a common goal: delivering outsized impact for patients.
Lux Capital VC Fund · New York, New York, United States · 50 investments in the past 12 months
Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series A, Seed, Series B
  • United States, United Kingdom, Canada
Portfolio highlights
  • JOYA — JOYA is the first employee skincare and wellness benefit platform. The company's goal is to provide tailored access to services such as skin cancer screenings, skin condition treatment, anti-aging, acne, and hair loss care from reputable physicians at an accessible cost.
  • Maven Clinic — Maven helps companies retain diverse talent, improve health outcomes, and reduce maternity and fertility costs. We support every path to parenthood: Pregnancy, Fertility, Egg Freezing, Adoption, Surrogacy, Infant Care, Breastmilk Shipping, and Manager Training.
  • Physical Intelligence — Physical Intelligence is bringing general-purpose AI into the physical world.
Vivo Capital VC Fund · Palo Alto, California, United States · 7 investments in the past 12 months
The firm is a 25-year-old global investment firm focused on healthcare with approximately $5.8 billion in AUM, which we have invested in over 290 public and private companies worldwide. Headquartered in Palo Alto, California, with offices in Asia. Our team consists of 50 multi-disciplinary professionals, including, physicians, scientists,entrepreneurs, operating executives, and industry experts. The firm operates as a multi-fund investment platform, covering growth equity, private equity including buyout, venture capital, and public equity. Vivo invests broadly in healthcare across all fund strategies, including biotechnology, pharmaceuticals, medical devices, and healthcare services, with a focus on the largest healthcare markets.
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Investment focus
  • Biotechnology, Health Care, Pharmaceutical
  • Series B, Series C, Series A
  • United States, China, United Kingdom
Portfolio highlights
  • Zenas BioPharma — Enabling patients with autoimmune diseases to reimagine life
  • Ajax Therapeutics — Ajax Therapeutics is an NYC-based biotechnology company applying computational chemistry and structure-based technologies to develop novel small molecules for hematologic malignancies
  • Serán Bioscience — Leading pharmaceutical innovator offering tailored drug solutions with comprehensive analytical and manufacturing services for biotech and pharma.
iSelect Fund VC Fund · St Louis, Missouri, United States
Venture investing in Food, Health, and AgTech. A generational investment thesis. Food is Health is longevity
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Investment focus
  • Biotechnology, Health Care, Agriculture
  • Seed, Series A, Series B
  • United States, Australia
Portfolio highlights
  • MEND — Mend is the scientifically proven way to heal and enhance your body faster.
  • Triplebar — Triplebar provides sustainability, biotechnology, and synthetic biology research.
  • Pluton Biosciences — The miniscule organisms Pluton Biosciences discover possess the power to create global change. Pluton quickly and inexpensively taps into the diverse world of bacteria, fungi and viruses to discover next-generation products for carbon sequestration, agriculture, pharmaceutical, biomaterials and bioremediation.Pluton Bioscience's discoveryprocess generates diverse commercialization options, including: Organisms (biological products), Small Molecule Chemistries (fermentable and non-fermentable) and New Traits (scale dependent).
Breakout Ventures VC Fund · San Francisco, California, United States
Breakout Ventures is a new, early stage fund that backs bold scientist entrepreneurs working at the intersections of technology, biology, materials, and energy.
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Investment focus
  • Biotechnology, Life Science, Therapeutics
  • Seed, Series B, Series A
  • United States
Portfolio highlights
  • CytoVale — Categorized is a medical technology company that revolutionizes diagnostics using cell mechanics and machine learning. The company was founded in 2013 by Ajay Shah and Dino Di Carlo and is based in San Francisco, California, United States.
  • Parallel Bio — Using the immune system to cure disease. Parallel Bio uses a human immune system in a dish and AI to discover drugs more likely to work in patients.
  • TFC Therapeutics — TFC Therapeutics is a biotechnology company developing novel biologics to target and eliminate key drivers of cancer.
Roche Venture Fund VC Fund · Basel, Basel-Stadt, Switzerland
The Roche Venture Fund is the name given to the corporate venture fund of the healthcare company Roche. Roche has allocated CHF 500 million to invest in and develop commercially successful innovative life science companies. Roche has been investing in early stage companies as part of collaborations since the early-1990s and independent ofcollaborations since 2002. All equity investments made by Roche in biotech and diagnostics companies (including collaboration investments) are negotiated and managed by the Roche Venture Fund. In the past 20 years, the Roche Venture Fund has invested in over 60 companies globally. Currently, Roche Venture Fund has a portfolio of around 30 companies located in 10 countries across Europe, North America and the Pacific Region. The fund is an evergreen fund with CHF 500 million available of which approximately 40% is currently invested.The Roche Venture Fund is a committed long-term stable investor with sufficient money reserved in their fund for follow-on financing rounds. As part of a multinational healthcare company, the Roche Venture Fund has access to considerable expertise both internally and externally. We co-invest with leading venture funds, including other corporate venture funds, on a regular basis.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series B, Series A, Series C
  • United States, United Kingdom, Spain
Portfolio highlights
  • DiogenX — We incorporated DiogenX with the objective to provide new therapeutic solutions for diabetic patients. With Patrick Collombat and the team, we are focused on developing a first-in-class regenerative treatment for type 1 diabetes. Benjamin Charles CEO See the team Latest News See more Our Work OUR APPROACH ABOUT DIABETES
  • Mironid — Google Analytics is a web analysis service provided by Google. Google utilizes the data collected to track and examine the use of www.mironid.com, to prepare reports on its activities and share them with other Google services. Google may use the data collected to contextualize and personalize the ads of its own advertising network.
  • MISSION Therapeutics — Deubiquitylating enzymes: multiple drug opportunities across therapeutic areas
Flagship Pioneering VC Fund · Cambridge, Massachusetts, United States · 6 investments in the past 12 months
We create breakthroughs in human health and sustainability and build bioplatform companies . Companies founded
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series B, Series C, Series A
  • United States, Canada, United Kingdom
Portfolio highlights
  • Mirai Bio — Mirai Bio has developed an open platform powered by AI to address the main drawbacks and manufacturing to develop the future of genetic medicine.
  • Inari — Inari is a biotech seed company that embraces diversity in every aspect of its business to drive innovation and help build a new food system. Our technology matches the complexity of nature using predictive design and multiplex gene editing to unlock the full potential of seed. We are always innovating, pushing the boundaries of what’s possible.Our SEEDesign platform is our point of distinction, using unsurpassed technology to enhance any crop for any geography to develop step-change products with a clear go-to-market approach.
  • Prologue Medicines — Prologue is systematically discovering the therapeutic potential of secreted proteins tuned through millennia of natural evolution to rapidly create powerful new medicines.
Horizons Ventures VC Fund · Hong Kong, Hong Kong Island, Hong Kong · 13 investments in the past 12 months
Investing in the deep science and technology that can propel humanity towards a radically better future.
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Investment focus
  • Biotechnology, Artificial Intelligence, Software
  • Series A, Series B, Seed
  • United States, United Kingdom, Canada
Portfolio highlights
  • Notpla — We are a combination of designers and chemists, engineers and entrepreneurs. We’re hard to define because what we’re doing hasn’t been done before. We create advanced packaging solutions that disappear, naturally.
  • Medal — Gamers live here. Medal is the best way to record, clip, edit, and share your gaming clips and videos. Clip, Edit, Share, and Relive your gaming moments.
  • ZeroAvia — ZeroAvia is producing the world's first practical zero emission aviation powertrain, initially targeting 20-seat airplanes to start replacing dirty jet fuel in regional transport
Foresite Capital VC Fund · San Francisco, California, United States · 9 investments in the past 12 months
We are a multi-stage investment firm, investing in companies that leverage biology and big data to transform healthcare.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series B, Series C, Series A
  • United States, United Kingdom, Australia
Portfolio highlights
  • Spear Bio — Successive Proximity Extension Amplification Reaction (SPEAR) technology from Spear Bio enables ultra-sensitive biomarker detection using ultra-small samples.
  • Chimagen Biosciences — Chimagen Biosciences is a company that is creating a novel class of multi-functional monoclonal antibodies for cancer therapy.
  • Foresight Diagnostics — We develop innovative diagnostics to advance decision-making in oncology drug development and patient care.
Dolby Family Ventures VC Fund · San Francisco, California, United States · 5 investments in the past 12 months
Investing in early-stage companies solving the biggest science and engineering challenges since 2014.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Seed, Series B
  • United States, Austria, Israel
Portfolio highlights
  • Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases
  • Progentos Therapeutics — Progentos Therapeutics develops an approach to treat multiple sclerosis that stimulates the body's natural repair mechanisms.
  • Esper Satellite Imagery — Welcome to Esper Satellite Imagery. Enjoy your Stay.
Connecticut Innovations VC Fund · Rocky Hill, Connecticut, United States · 13 investments in the past 12 months
At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.
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Investment focus
  • Health Care, Biotechnology, Software
  • Seed, Series A, Funding Round
  • United States, Israel, Canada
Portfolio highlights
  • AmpUp — Commercial electric vehicle (EV) charging network solutions made simple for everyone. Easily manage and analyze EV charging data from a single dashboard.
  • Oxylus Energy — Oxylus Energy provides new carbon utilization technology for the generation of e-fuels It strives to make CO2 capture and conversion competitive, scalable, and circular for a decarbonized future.
  • Air Company — We are a carbon utilization company working with industries to create planetary change, taking Earth's excess CO2 and converting it into carbon-negative alcohols and fuels.
Illumina Ventures VC Fund · Foster City, California, United States · 5 investments in the past 12 months
We invest in companies that are advancing the field of genomics and pioneering new applications in healthcare, agriculture, environmental science, and personal
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Investment focus
  • Biotechnology, Health Care, Life Science
  • Series A, Series B, Series C
  • United States, United Kingdom, France
Portfolio highlights
  • SyntaxBio — SyntaxBio develops CRISPR/Cas9-based, genetic programming platform that converts cells into biological computers using DNA-based instructions that read like lines of code. SyntaxBio's platform can program cells without the need for consistent external intervention.
  • Attovia Therapeutics — Attovia Therapeutics is a biotherapeutics pipeline developer focused on immune-mediated illness and oncology. The company uses the nanobody platform to create tiny format binders with low picomolar affinity, increased selectivity, quicker internalization, and rapid tissue penetration, thereby assisting cancer patients in being treated.
  • Predicta Biosciences — Our blood-based approach unlocks true precision medicine.
Pear VC VC Fund · Palo Alto, California, United States · 28 investments in the past 12 months
Pear VC partners with entrepreneurs from day zero to build category-defining companies.
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Investment focus
  • Software, Health Care, Artificial Intelligence
  • Seed, Series A, Pre-Seed
  • United States, Brazil, Colombia
Portfolio highlights
  • Advex AI — Advex AI assists the world's largest manufacturers in cutting costs and increasing productivity by producing highly dependable computer vision models in hours.
  • SweatPals — SweatPals is a home for all your fitness, wellness and mindfulness events, communities and friends
  • Matter Intelligence — Matter Intelligence is creating the most detailed map of the world using first-of-a-kind sensors to understand our planet like never before
Artis Ventures (AV) VC Fund · San Francisco, California, United States · 10 investments in the past 12 months
Artis Ventures has spent over a decade backing bold teams who take the hard path, building market-defining companies to re-shape, re-invent, and re-make industries.
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Investment focus
  • Health Care, Biotechnology, Software
  • Series A, Series B, Seed
  • United States, India, Germany
Portfolio highlights
  • Eko Health — At Eko every digital stethoscope from Eko comes with smart disease detection capabilities to help healthcare professionals confidently identify and diagnose heart and lung disease during physical exams.
  • Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
  • Second Front Systems — The continuous accreditation and deployment of commercial software is crucial for U.S. national security missions. With Second Front Systems' Game Warden platform, you'll be achieving exactly that.
JDRF T1D Fund VC Fund · Boston, Massachusetts, United States · 3 investments in the past 12 months
The JDRF T1D Fund (www.t1dfund.org) is a venture philanthropy fund exclusively devoted to finding and funding the best early-stage T1D commercial opportunities to accelerate the delivery of treatments, preventions, and cures to patients. It was created to solve a critical funding gap in the T1D drug and device development pipeline. Throughpartnerships with private capital, including venture capital, pharma and foundations, the T1D Fund anticipates that it will be able to attract substantially more private investment to the T1D field than occurs today. The T1D Fund will initially focus on artificial pancreas systems, metabolic control, beta cell replacement, prevention, and beta cell restoration therapies, with an exclusive priority on the best commercial opportunities. The T1D Fund will reinvest any realized gains into new investments to further its mission.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Funding Round, Series B
  • United States, France, Italy
Portfolio highlights
  • vTv Therapeutics — vTv Therapeutics, a pharmaceutical company, focuses on the discovery and development of human therapeutics to fill unmet medical needs. Its mission is to utilize its innovative technology to rapidly translate the functional modulation of human proteins into safe and effective medicines.vTv Therapeutics has a pipeline of small molecule clinicaland pre-clinical drug candidates for the treatment of a wide range of human diseases including central nervous system disorders, metabolic disorders, inflammation, and cancer. The company has built its product candidate portfolio through internal discovery and is advancing its product candidates through in-house research and development efforts. The quality and breadth of vTv's product candidate pipeline, platform technology, scientific team, and strategic collaborations have enabled it to become a fully integrated pharmaceutical company.The company's commitment to drug discovery is reflected in its medical solutions and the many exciting potential new treatment options in its pipeline. The company's major R&D activities have focused on central nervous system disorders, metabolic disorders, inflammation and oncology.vTv Therapeutics is advancing several proprietary drug candidates. The company's lead candidate, azeliragon (aka TTP488), is a novel, orally bioavailable small molecule compound that is being developed for the treatment of Alzheimer's disease. In Phase 2 clinical trial in patients with mild to moderate Alzheimer's disease, azeliragon showed a statistically significant difference of more than 3 points in ADAS-cog at 18 months compared to placebo.Azeliragon has been granted Fast Track Designation and agreement on its Phase 3 protocol has been reached with FDA via a Special Protocol Assessment (SPA). The Phase 3 study in patients with mild Alzheimer's disease was initiated in April 2015 with a clear path forward to registration with the aim to demonstrate disease modification.vTv Therapeutics is also prosecuting the clinical development of TTP399, a novel functionally liver-selective Glucokinase Activator ("GKA") for the treatment of type 2 diabetes. In a Phase 2a study, TTP399 normalized patients' HbA1c without inducing hypoglycemia, after only six weeks of treatment. A six-month Phase 2 study is ongoing.
  • Eledon Pharmaceuticals — Eledon Pharmaceuticals, Inc. is a clinical-stage biotechnology company using its expertise in targeting the CD40L pathway to develop potential treatments for people undergoing organ or cellular transplantation, and for people with autoimmune and neurodegenerative disease.
  • Cour Pharmaceuticals Development — COUR Pharmaceuticals is developing first-in-class therapies designed to reprogram the immune system to achieve antigen-specific tolerance...
Khosla Ventures VC Fund · Menlo Park, California, United States · 63 investments in the past 12 months
Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.
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Investment focus
  • Software, Health Care, Artificial Intelligence
  • Series A, Series B, Seed
  • United States, India, United Kingdom
Portfolio highlights
  • LuxWall — LuxWall is accelerating the global transition to net zero by upgrading windows and glass into transparent insulation for buildings.
  • RedoxBlox — RedoxBlox offers thermochemical energy storage technology for natural gas power plant operators. It helps power plant operators drastically reduce carbon and nitrogen oxides emissions, its solution integrates with the existing natural gas power plant infrastructure, minimizes impact on plant total capital costs, increases grid resiliency andsafety, and is recyclable, non-toxic, and non-combustible, enabling industries with renewables grid through the deployment of large-scale long-duration energy storage.The company was founded in 2020 and is based in East Lansing, Michigan.
  • Mooncake Labs — Mooncake Labs is building the modern lakehouse for every developer and application. We are an open source studio based in SF.
Digitalis Ventures VC Fund · New York, New York, United States · 12 investments in the past 12 months
Engineering solutions to complex problems in health through venture investment and company creation.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series A, Seed, Series B
  • United States, United Kingdom, China
Portfolio highlights
  • Reema Health — Transforming the way people navigate the gaps between health care and social care. Reema combines a 24/7 AI-based confidant with in-person community guides to help people meet their social needs.
  • Alpha9 Theranostics — Through peptide engineering and iterative design, Alpha9 Oncology creates highly selective, potent radiopharmaceuticals for cancer patients.
  • Terray Therapeutics — Everything small molecule drug discovery should be.
venBio Partners VC Fund · San Francisco, California, United States · 7 investments in the past 12 months
venBio invests in promising companies at various stages: from early to late stage, and from academic startups to spinouts. We tend to lead most of our investments, and we enjoy building syndicates and teams.We are mindful of potential acquisition partners from the outset, and we ensure that our companies are best positioned to meet theirrequirements. This includes IP, CMC, and the details of clinical trials, including indication, trial design, endpoints, powering, and regulatory considerations. Our team’s expertise and involvement helps companies make a bigger impact, and this leads to impactful and lasting relationships with the leaders that we work with.
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Investment focus
  • Biotechnology, Health Care, Pharmaceutical
  • Series A, Series B, Series C
  • United States, Canada, Switzerland
Portfolio highlights
  • Vicebio — Vicebio is committed to employing the Molecular Clamp Technology to create vaccines against next-generation respiratory viruses. Vicebio is a biopharmaceutical business that creates innovative vaccinations to prevent potentially fatal respiratory viral infections.
  • Axonis Therapeutics — AXONIS Therapeutics, Inc. is advancing breakthrough discoveries to develop first-in-class therapies for neurological disorders.
  • Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
Refactor VC Fund · Burlingame, California, United States
Refactor Capital is an early-stage venture capital firm that invests in founders solving fundamental human problems.
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Investment focus
  • Health Care, Biotechnology, Medical
  • Seed, Series A, Series B
  • United States, United Kingdom, New Zealand
Portfolio highlights
  • Astranis — Four billion people still have no internet access. Astranis is here to change that. We're making small satellites for geostationary orbit, recently signed a contract to triple the satellite internet capacity of Alaska, and raised our Series A from Andreessen Horowitz.
  • Hyfé — Hyfé Foods is a biotech company producing ingredients by leveraging fungal fermentation to upcycle water byproducts from food manufacturers.
  • Macro Oceans — Transforming seaweed into low-carbon chemicals for materials, food, cosmetics and more
Felicis VC Fund · Menlo Park, California, United States · 27 investments in the past 12 months
Backing founders building iconic companies that transcend boundaries
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Investment focus
  • Software, SaaS, Health Care
  • Series A, Seed, Series B
  • United States, Canada, Germany
Portfolio highlights
  • MemGPT — MemGPT is developing a language model system that enhances LLMs with long-term memory capabilities, offering features like virtual context management and function calling for AI applications.
  • Redactive — Redactive.ai is an Enterprise AI enablement platform that accelerates regulated organisations to secure & remediate their operational (unstructured) data, preparing it to be used by AI applications (eg: Co-pilots), along with providing engineering teams inside the enterprise the tools to build their own AI use cases securely with any LLM.
  • Slingshot AI — Slingshot is an AI research company driven by our mission to exponentially increase global access to mental healthcare.We’re developing technology to help humans feel and perform better, be more connected, and adapt to the future in a time where the demand for mental health support far exceeds providers by 10,000:1, and the large-scale changesahead are unprecedented.By leveraging AI to delve deep into human psychology, we expect to learn something about human nature that no humans have before, in order to help people change their minds.Based in NYC and London, our cross-disciplinary team of researchers, engineers, and broader mental health experts is dedicated to building tools that empower individuals to take on any challenge that arises.
Catalio Capital Management VC Fund · Baltimore, Maryland, United States · 17 investments in the past 12 months
Catalio Capital Management was created by George Petrocheilos and Dr. Jacob Vogelstein to invest in breakthrough biomedical technology companies created or referred by Catalio Capital Management, an elite group of world-renowned, serial scientist-entrepreneurs.
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Investment focus
  • Biotechnology, Health Care, Life Science
  • Series A, Series B, Series C
  • United States, France, Israel
Portfolio highlights
  • Noetik — Noetik is an AI-native biotechnology company. Our mission is to leverage advanced machine learning methods to discover and develop cancer immunotherapies.
  • InSightec — Discover the therapeutic power of Focused Ultrasound. By harnessing acoustic energy, you can help transform patient lives.
  • Imperative Care — Imperative Care focuses on developing a portfolio of innovative solutions to address the vast and urgent unmet needs in stroke care. It focuses on medical technology designed to expedite and improve the effectiveness of treatment, giving patients a chance for optimal recovery.
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