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Top 50 Machine Learning Startup Investors in United States (November 2026)

The most active venture capital funds and angel investors investing in United States Machine Learning startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Machine Learning startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Alumni Ventures
VC Fund
166 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Health Care $850k–$75M
Right Side Capital Management
VC Fund
137 United States, Canada, United Kingdom Pre-Seed, Convertible Note, Seed Software, Artificial Intelligence, SaaS $50k–$1.5M
SV Angel
VC Fund
81 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $935k–$100M
Andreessen Horowitz
VC Fund
76 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Information Technology $1.5M–$116M
Liquid 2 Ventures
VC Fund
69 United States, Mexico, Canada Seed, Pre-Seed, Series A Software, Artificial Intelligence, Information Technology $125k–$48M
New Enterprise Associates
VC Fund
60 United States, China, India Series A, Series B, Series C Software, Health Care, Biotechnology $5.7M–$100M
Accel
VC Fund
60 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, SaaS $1.3M–$70M
Lightspeed Venture Partners
VC Fund
57 United States, India, China Series A, Seed, Series B Software, Artificial Intelligence, Information Technology $2M–$125M
DCVC
VC Fund
57 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Machine Learning $1M–$130M
Khosla Ventures
VC Fund
57 United States, United Kingdom, India Series A, Seed, Series B Artificial Intelligence, Software, Health Care $1.6M–$100M
Gaingels
VC Fund
54 United States, Canada, United Kingdom Seed, Series A, Venture - Series Unknown Software, Artificial Intelligence, Health Care $72k–$35M
Flybridge
VC Fund
51 United States, Canada, United Kingdom Seed, Pre-Seed, Series A Software, Artificial Intelligence, Health Care $100k–$21M
Soma Capital
VC Fund
50 United States, India, Mexico Seed, Pre-Seed, Series A Software, Artificial Intelligence, FinTech $125k–$35M
General Catalyst
VC Fund
50 United States, India, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Health Care $1.6M–$123M
Google Ventures
VC Fund
49 United States, United Kingdom, Israel Series A, Series B, Seed Software, Health Care, Biotechnology $1.1M–$125M
BootstrapLabs
VC Fund
48 United States, Estonia, Malaysia Seed, Series A, Pre-Seed Artificial Intelligence, Software, Machine Learning $250k–$20M
Greycroft
VC Fund
48 United States, United Kingdom, Germany Series A, Seed, Series B Software, Artificial Intelligence, E-Commerce $1.5M–$79M
Sequoia Capital
VC Fund
48 United States, China, India Series A, Series B, Seed Software, Artificial Intelligence, Information Technology $1.2M–$100M
Bossa Invest
VC Fund
47 United States, Brazil, Mexico Seed, Pre-Seed, Venture - Series Unknown Software, Information Technology, Financial Services $40k–$36M
SOSV
VC Fund
46 United States, China, Canada Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software $25k–$5M
Madrona
VC Fund
46 United States, Canada, Israel Series A, Seed, Series B Software, Artificial Intelligence, Information Technology $1.5M–$75M
Bloomberg Beta
VC Fund
45 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1M–$65M
Amplify Partners
VC Fund
44 United States, Canada, Israel Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $2M–$80M
AME Cloud Ventures
VC Fund
44 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.1M–$75M
Ulu Ventures
VC Fund
44 United States, Mexico, Singapore Seed, Series A, Pre-Seed Software, Financial Services, FinTech $150k–$33M
Bain Capital Ventures
VC Fund
43 United States, United Kingdom, Canada Series A, Series B, Seed Software, Artificial Intelligence, Information Technology $2M–$62M
Lux Capital
VC Fund
43 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.5M–$150M
Streamlined
VC Fund
42 United States, Mexico, Colombia Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1M–$68M
Eniac Ventures
VC Fund
41 United States, Canada, Spain Seed, Series A, Series B Software, Artificial Intelligence, Mobile $1.1M–$40M
BoxGroup
VC Fund
40 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Health Care $1.5M–$100M
First Round Capital
VC Fund
40 United States, Canada, India Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.2M–$63M
Intel Capital
VC Fund
39 United States, China, Israel Series B, Series A, Series C Software, Information Technology, Artificial Intelligence $4.5M–$90M
Founders Fund
VC Fund
37 United States, United Kingdom, Germany Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.6M–$100M
Kleiner Perkins
VC Fund
37 United States, China, United Kingdom Series B, Series A, Series C Software, Artificial Intelligence, Information Technology $5M–$110M
Village Global
VC Fund
37 United States, United Kingdom, India Seed, Pre-Seed, Series A Software, Artificial Intelligence, Financial Services $250k–$23M
Hyperplane
VC Fund
36 United States, Canada, Israel Seed, Series A, Series B Software, Artificial Intelligence, Machine Learning $1.5M–$54M
Everywhere Ventures
VC Fund
36 United States, United Kingdom, Australia Seed, Pre-Seed, Series A Software, Health Care, Artificial Intelligence $250k–$20M
Sierra Ventures
VC Fund
36 United States, China, Canada Series A, Seed, Series B Software, Artificial Intelligence, Information Technology $2M–$38M
Bessemer Venture Partners
VC Fund
36 United States, India, Israel Series B, Series A, Series C Software, Artificial Intelligence, Information Technology $5M–$101M
8VC
VC Fund
35 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Health Care $2.5M–$175M
Gradient
VC Fund
34 United States, The Netherlands, Germany Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $2.6M–$58M
Pear VC
VC Fund
34 United States, Brazil, Colombia Seed, Pre-Seed, Series A Software, Artificial Intelligence, Information Technology $175k–$40M
Cultivation Capital
VC Fund
34 United States, Australia, Canada Seed, Series A, Venture - Series Unknown Software, Health Care, SaaS $475k–$15M
Uncork Capital
VC Fund
33 United States, Canada, Israel Seed, Series A, Series B Software, SaaS, Artificial Intelligence $1.3M–$50M
Felicis
VC Fund
32 United States, Canada, United Kingdom Series A, Seed, Series B Software, Artificial Intelligence, SaaS $1.2M–$75M
Greylock
VC Fund
32 United States, Israel, United Kingdom Seed, Series A, Series B Software, Information Technology, Artificial Intelligence $1.2M–$62M
Two Sigma Ventures
VC Fund
32 United States, Canada, Mexico Series A, Seed, Series B Software, Artificial Intelligence, Machine Learning $1.4M–$120M
Index Ventures
VC Fund
31 United States, United Kingdom, Germany Series A, Series B, Seed Software, Artificial Intelligence, E-Commerce $1.3M–$102M
Homebrew
VC Fund
31 United States, Mexico, Brazil Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.5M–$50M
Foundation Capital
VC Fund
31 United States, Mexico, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.6M–$60M
Access all 10881 investors in United States Machine Learning startups.

Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 166 investments in United States Machine Learning startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 2705
  • Round size: Seed $850k–$9.9M; Series A $3.5M–$32M; Series B $8M–$75M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: Likely actively investing — fresh fund, raised $90k in 2026

Portfolio highlights

  • NextDroid — NextDroid - We're Doing Something Different
  • Hello Patient — Healthcare AI that gets your team off the phone & in front of patients
  • Alva Energy — Alva Energy is a nuclear solution based firm that aids challenges related to nuclear power offering on time delivery of nuclear megawatts.
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Right Side Capital Management
VC Fund · San Francisco, California, United States · 137 investments in United States Machine Learning startups

Systematic Pre-Seed Startup Capital

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Pre-Seed, Convertible Note, Seed
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 2192
  • Round size: Seed $50k–$1.5M; Pre-Seed $50k–$450k; Convertible Note $50k–$400k
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely actively investing — fresh fund, raised $55M in 2025

Portfolio highlights

  • Athel AI — Athel AI provides an AI-powered clinical intake platform for physicians and healthcare teams. Its tools conduct patient interviews through voice, chat, and video, capture clinical histories, and generate structured summaries for physicians. The platform also supports AI-assisted reception, dictation, multilingual interviews, and automated clinical workflows. Athel AI provides clinical decision support while keeping diagnosis and treatment decisions under the physician's authority.
  • Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
  • TasksMind — tasksmind turns urgent but ambiguous bug reports into fixed code and customer follow-up, so bugs don't become churn.
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SV Angel
VC Fund · San Francisco, California, United States · 81 investments in United States Machine Learning startups

SV Angel offers founders assistance with key inflection points, including capital raising, strategic networking, business development, talent acquisition, and corporate transactions. Through its relationship network, the organization connects emerging businesses with industry partners, executive advisors, and ecosystem resources. Additionally, the firm provides guidance on corporate governance, operational scaling, and management decisions to support technology enterprises throughout their growth stages.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 1487
  • Round size: Seed $935k–$11M; Series A $3M–$35M; Series B $8M–$100M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $430M in 2025

Portfolio highlights

  • Hyperpublic — Hyperpublic is an open database of people, places, and things tied to a specific location. Anyone can add objects to the database and developers will be able to build applications on top of the data.
  • Dream — Dream Technologies develops generative AI software for home and interior design. The company offers Dream, a platform that converts residential ideas into detailed, construction-ready architectural plans. Its tools help property owners and designers move from abstract concepts to precise layouts tailored to specific spaces and use patterns. The platform uses interactive 3D graphics and custom machine learning models to manage visualization, spatial layout, and structural planning. Dream Technologies focuses on streamlining design workflows for both consumer and commercial home design projects.
  • Daletlabs — Dalet Labs is pioneering the future of e-commerce through Generative AI and visual product discovery. Its platform transforms AI-generated imagery into interactive shopping experiences featuring real, purchasable products. By combining creativity, personalization, and technology, Dalet Labs is redefining how consumers discover and shop for products.
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Andreessen Horowitz
VC Fund · Menlo Park, California, United States · 76 investments in United States Machine Learning startups

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 2217
  • Round size: Seed $1.5M–$15M; Series A $8.7M–$55M; Series B $17M–$116M
  • Lead/follow: 48% lead, 52% follow
  • Last fund: Likely actively investing — fresh fund, raised $1.2B in 2026

Portfolio highlights

  • Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
  • Stoïk — Stoïk is a cyber insurance company that integrates cybersecurity software with insurance protection, helping businesses manage their cyber risks effectively. Stoïk empowers brokers by offering clients comprehensive insurance policies and protection against cyber risks. Its mission is to equip brokers with the tools to help their clients insure andsafeguard against cyber threats.Stoïk's unique product simplifies the underwriting process using automated tests, replacing traditional questionnaires. It also provides continuous risk prevention through integrated cybersecurity tools and ensures swift, effective incident response with an in-house team of crisis management experts.
  • Supersonik — Supersonik provides an AI-powered platform for SaaS companies to offer 24/7 interactive product demos, enabling prospects to explore and personalize demos instantly without scheduling or manual intervention.
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Liquid 2 Ventures
VC Fund · San Francisco, California, United States · 69 investments in United States Machine Learning startups

Liquid 2 Ventures is a venture capital firm that invests in early-stage startups, primarily at the pre-seed and seed stages. It provides capital, founder guidance, operational support, and access to a network of entrepreneurs, investors, and industry contacts.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Mexico, Canada

Investor stats

  • Total investments: 1250
  • Round size: Seed $1.1M–$9.1M; Pre-Seed $125k–$2.7M; Series A $6M–$48M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fresh fund, raised $12M in 2026

Portfolio highlights

  • Albedo — Aerial quality imagery - from space.
  • Eden — Eden unifies medical imaging operations with clinical AI: PACS, teleradiology, AI-assisted diagnosis and structured reporting, deployed across 2,600+ imaging departments.
  • Kivo Health — Kivo Health is a telehealth lung care company that provides rehab for chronic lung disease.
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New Enterprise Associates
VC Fund · Menlo Park, California, United States · 60 investments in United States Machine Learning startups

Foundational partners to ambitious founders at every stage of company-building.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, India

Investor stats

  • Total investments: 2171
  • Round size: Series A $5.7M–$53M; Series B $10M–$85M; Series C $15M–$100M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely still investing — raised $468M in 2024

Portfolio highlights

  • Uhana — Modernize your RAN to be open and programmable, built with a rich ecosystem of partners. Learn about VMware RAN Intelligent Controller (RIC).
  • erytech — ERYtech Pharma, set up in Lyon (France) in 2004, specializes in the encapsulation of therapeutic molecules and enzymes in red blood cells. It has achieved a major breakthrough in the fields of cancer and enzyme therapy by significantly increasing the therapeutic index of the encapsulated molecule or enzyme.
  • Sportsrocket — Sportsrocket is a New York-based company working to give sports fans access to live games and events, highlights, and shows. The company works with leading leagues, publishers, and rights-holders, including Major League Soccer, the PGA Tour, Scout Media, and AS Roma, to create and power customized OTT platforms. Incubated by Bedrocket Media Ventures, Sportsrocket's innovative approach is based on a proprietary sports media operating system, that offers an integrated solution for the production, distribution, management, and monetization of sports media across all platforms.
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Accel
VC Fund · Palo Alto, California, United States · 60 investments in United States Machine Learning startups

First partner to exceptional teams everywhere

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 2569
  • Round size: Seed $1.3M–$11M; Series A $4.4M–$41M; Series B $9.3M–$70M
  • Lead/follow: 44% lead, 56% follow
  • Last fund: Likely actively investing — fresh fund, raised $750M in 2026

Portfolio highlights

  • MobStac — Developer of a cloud-based mobile marketing platform designed to connect the digital and physical worlds through the use of innovative technology. The company's platform is based on the principals of proximity marketing and engage customers in a personalized, context-aware way that leverages indoor location and proximity, enabling businessesand brands to leverage BLE beacon technology to deliver context-rich experiences to their end users.
  • Krux — Use Salesforce's data management platform (DMP) to unify your data and strengthen customer relationships across every touchpoint.
  • Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.
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Lightspeed Venture Partners
VC Fund · Menlo Park, California, United States · 57 investments in United States Machine Learning startups

Lightspeed Venture Partners is a multi-stage venture capital firm focused on accelerating disruptive innovations and trends.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: United States, India, China

Investor stats

  • Total investments: 2493
  • Round size: Seed $2M–$26M; Series A $7M–$82M; Series B $15M–$125M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely actively investing — fresh fund, raised $600M in 2025

Portfolio highlights

  • Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
  • Whizzo — Whizzo specializes in materials science-driven manufacturing of engineered fashion and technical textiles. Our expertise lies in creating and executing innovative textile blends tailored for applications across automotive, agriculture, medical textiles, and engineered fashion.
  • Daletlabs — Dalet Labs is pioneering the future of e-commerce through Generative AI and visual product discovery. Its platform transforms AI-generated imagery into interactive shopping experiences featuring real, purchasable products. By combining creativity, personalization, and technology, Dalet Labs is redefining how consumers discover and shop for products.
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DCVC
VC Fund · San Francisco, California, United States · 57 investments in United States Machine Learning startups

We are deep tech venture capital.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 556
  • Round size: Seed $1M–$9M; Series A $5.7M–$45M; Series B $14M–$130M
  • Lead/follow: 22% lead, 78% follow
  • Last fund: Likely actively investing — fresh fund, raised $5M in 2026

Portfolio highlights

  • CH4 Global — CH4 Global is an aquaculture solutions provider dedicated to urgently impacting climate change at scale. Lead by a world-class team of senior business builders, scientists and entrepreneurs, the company is initially leveraging proven science and technology for growing seaweed into innovative new livestock supplement that reduces methane produced bycows by up to 90%. Among early investors are a select group of prominent family offices and private investors. CH4 Global have also received non-dilutive capital support from government organizations from around the world. CH4 Global is a Delaware corporation based in Henderson, NV.
  • Kairos Power — Building the future of clean energy through iterative development and vertical integration. Kairos Power's advanced reactors deliver reliable, safe nuclear power at scale.
  • BioStack — BioStack Platforms develops data infrastructure and simulation environments for healthcare and drug discovery AI. The company builds proprietary preclinical and clinical data pipelines that connect longitudinal, multimodal medical data such as EHRs, imaging, ECGs, labs, notes, audio, and outcomes. It structures this information intomachine-learning-ready datasets and workflow-aligned simulation environments rather than static text corpora. These environments support post-training, reinforcement learning, and multi-agent reasoning for medical AI systems. BioStack Platforms serves AI labs, biotechnology startups, pharmaceutical teams, and data providers that need domain-specific datasets, causal inference support, and robust reward models. Its offerings are used to test, evaluate, and train medical AI models on real-world clinical workflows before deployment in practice.
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 57 investments in United States Machine Learning startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech, offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Artificial Intelligence, Software, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 1552
  • Round size: Seed $1.6M–$23M; Series A $5.3M–$47M; Series B $11M–$100M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely actively investing — fresh fund, raised $31M in 2026

Portfolio highlights

  • Seeo — Daftar akun togel resmi bisa melalui via dana, ovo, gopay, linkaja kami juga menyediakan berbagai link togel terpercaya seperti bo togel hadiah 2d 200rb, bandar togel hadiah 4d 10 juta terpercaya, situs togel resmi dan terpercaya, agen togel terpercaya, daftar bandar togel terbesar dan terpercaya, bandar togel terbesar, situs togel prize 123, bo togel bolak balik dibayar dan banyak lainnya yang kami sediakan untuk pencinta link togel resmi di Indonesia.
  • Anrok — Anrok automates sales tax compliance across your financial stack, so you can grow your SaaS business in any market.
  • LanzaTech — LanzaTech offers a technology platform that transforms industrial waste gases such as carbon monoxide and carbon dioxide into valuable chemical intermediates and fuels through microbial gas fermentation. The company’s process captures emissions from heavy-industry sources and uses specialized microbes to convert those gases into ethanol, which is then refined into materials such as monoethylene glycol for packaging, solvents, proteins, and sustainable aviation fuels. LanzaTech integrates its bioconversion system with industrial emitters, enabling the reuse of carbon streams that would otherwise be released into the atmosphere, and supplies downstream manufacturers in sectors including packaging, textiles, and aviation with fossil-alternative feedstocks.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Gaingels
VC Fund · New York, New York, United States · 54 investments in United States Machine Learning startups, 71 in the past 12 months

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital to date.  The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Venture - Series Unknown
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 1354
  • Round size: Seed $1M–$8.1M; Series A $5M–$35M; Venture - Series Unknown $72k–$13M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fresh fund, raised $140k in 2026

Portfolio highlights

  • Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
  • North.cloud — Automate your enterprise-grade cloud finance with zero effort. Our AI reduces your cloud bill by 50% without any risk, contracts, or technical work.
  • Uvi — Uvi provides infrastructure that serves as a context and reasoning layer for enterprise AI agents. The platform resolves internal corporate vocabulary, tracks dependencies, and reconstructs the decision-making intent scattered across disparate systems like Jira, GitHub, and Slack. By unifying data fragments into an integrated knowledge network, it enables AI tools to process query objectives accurately while enforcing existing user access permissions at the retrieval stage.
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Flybridge
VC Fund · Boston, Massachusetts, United States · 51 investments in United States Machine Learning startups

New York and Boston Based Early-Stage Venture Capital Firm Backing Seed Stage AI Companies. Focused on AI Enablement, Developer Platforms, Agentic Business Applications, and Native AI for Human Ingenuity

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 963
  • Round size: Seed $1M–$7M; Pre-Seed $100k–$2.6M; Series A $4.4M–$21M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: Likely actively investing — fresh fund, raised $100M in 2025

Portfolio highlights

  • Augmeta.ai — AI Operators work 24/7 across your systems to stop revenue leaks and chase upside, acting within your goals and guardrails or alongside your team.
  • BoobyBiome — BoobyBiome harnesses breast milk microbiome science to develop products to improve infant health
  • Lighter Living — Marjolein Brugman is responsible for bringing the Pilates Method to the mainstream. An accident 10 years ago taught her about the profound benefits of Pilates as she rehabilitated her own hips and watched her life change. Marjolein began her Pilates training in New Mexico, in 1997 and has continued to study and learn about Pilates all over theworld. Her dedication to the understanding of postural health and whole body fitness and her vast teacher training has made her the perfect spokesperson for the Pilates Method. She was instrumental in producing the first educational advertisement about Pilates in 1995 and has spent the last 9 years demonstrating and educating communities, worldwide via workshops and television. Together with Stamina Products, she has developed affordable Pilates equipment with training videos for home use. The recent launch of her Basic AeroPilates® Reformer training through SCW has been received with great enthusiasm by the fitness industry.
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Soma Capital
VC Fund · San Francisco, California, United States · 50 investments in United States Machine Learning startups, 52 in the past 12 months

Welcome to Soma Capital

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Investment focus

  • Industry: Software, Artificial Intelligence, FinTech
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, India, Mexico

Investor stats

  • Total investments: 1093
  • Round size: Seed $1.1M–$8.5M; Pre-Seed $125k–$3.8M; Series A $5M–$35M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $37M in 2026

Portfolio highlights

  • Rebill — Rebill.com is the payments and subscriptions platform specifically designed for digital businesses and global companies scaling in Latin America.With our platform and API, companies can integrate over 100 local payment methods from the region, including cards, bank transfers, cash, and even wallets. In addition, they always receive the best humansupport with fair pricing and utmost transparency, enabling them to scale across the region 10 times faster.We are backed and have received investment from some of the world's leading funds such as Tiger Global Management, Soma Capital, SV Angel, Y Combinator, as well as incredible angel investors like Guillermo Rauch (Vercel), Arash Ferdowsi (Dropbox), among others.
  • FirstWork — Applied AI for frontline enterprises. Forward-deployed AI agents that automate workforce operations inside your existing systems.
  • Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.
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General Catalyst
VC Fund · Cambridge, Massachusetts, United States · 50 investments in United States Machine Learning startups

Investing in powerful, positive change that endures

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 2356
  • Round size: Seed $1.6M–$18M; Series A $6.5M–$75M; Series B $14M–$123M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: Likely actively investing — fund raised in 2026

Portfolio highlights

  • Lemonade — Lemonade operates as a full-stack insurance company powered by AI and behavioral economics and driven by social good. It is a licensed insurance carrier, offering homeowners and renters insurance. Lemonade replaces brokers and bureaucracy with bots and machine learning, delivering zero paperwork and instant everything. The company uses artificialintelligence and behavioral economics to set rates for the homes and renters it insures. Lemonade was founded in Tel Aviv, Israel, in 2015 and is headquartered in New York, NY, United States.
  • Datalogix — Datalogix® is the industry-recognized leader at connecting digital media and offline purchasing data. We help more than half of the top 100 consumer marketers increase the effectiveness and measurability of their advertising. DLX Platform®, encompasses over $1 trillion in consumer spending and powers campaigns for more than 75% of online mediacompanies. DLX ROI® is rapidly becoming the industry standard for measuring offline sales lift for digital media. Datalogix also offers predictive analytics for Direct Mail, and integrated media solutions via the DLX Net. Our expertise spans the major consumer segments, including Retail, CPG, Automotive, Telecom, Travel and Financial Services. We are based in Colorado, with offices in New York City, San Francisco, Boston, Chicago, Detroit, and London.
  • Ayr Energy — Ayr Energy designs, engineers, manufactures, and supplies power transformers, distribution transformers, switchgear, and circuit breakers.
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Google Ventures
VC Fund · Mountain View, California, United States · 49 investments in United States Machine Learning startups

GV supports innovative founders moving the world forward.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 1582
  • Round size: Seed $1.1M–$14M; Series A $6M–$100M; Series B $15M–$125M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2014

Portfolio highlights

  • Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
  • ngmoco — ngmoco ("Next Generation MObile COmpany") is creating and producing games for the iPhone. CEO Neil Young is a former executive from Electronic Arts, where he oversaw the development of several hit titles. Another EA vet and partner at Kleiner Perkins, Bing Gordon, sits on the board. Kleiner is an investor through its iFund.
  • SolveAI —
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BootstrapLabs
VC Fund · San Francisco, California, United States · 48 investments in United States Machine Learning startups

Founded in 2008, BootstrapLabs, an Ares company, is a leading Venture Capital firm based in Silicon Valley and focused on Applied Artificial Intelligence. BootstrapLabs was one of the first VC firms to build an AI-first investment strategy and seeks to invest in visionary founders who solve some of today’s most important and valuable opportunities by applying Artificial Intelligence. BootstrapLabs is often the first institutional money and acts as a lead investor in the early stages, with follow-on capital at the growth stages. Through our Venture Studios and Venture Capital funds, we are investing in Artificial Intelligence applied to The Future of Work (FoW)/Productivity, Mobility, Health, Financial Infrastructure, Digital Infrastructure, Energy/Climate, and AI-enabling technologies. As entrepreneurs ourselves, we know it takes an experienced team amplified by a nurturing community to build successful companies, so we stand by our founders in good times and bad times, because the road to success is paved with setbacks, challenges, and lessons learned from past failures – and building something big is hard. Ultimately we believe technology should always be used to create a positive impact on society, and that founders should always place fellow humans at the heart of their vision.

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Investment focus

  • Industry: Artificial Intelligence, Software, Machine Learning
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Estonia, Malaysia

Investor stats

  • Total investments: 143
  • Round size: Seed $250k–$4.5M; Pre-Seed $2M–$2.6M; Series A $5M–$20M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Pryon — Pryon is an artificial intelligence company focused on enterprise knowledge management. Its natural language processing platform transforms unstructured data into experiences that increase productivity with unmatched accuracy and speed. Pryon’s automated machine learning engines deliver rapid time to value by enriching existing content. Thisno-code approach prevents operational disruption and allows organizations to quickly maximize the business value trapped within their information assets. Pryon was founded by Igor Jablokov, whose previous company defined the state of the art for AI assistants and was acquired by Amazon to form the basis for Alexa.
  • Looq AI — Search indexed the web. LLMs indexed human knowledge. Looq AI is indexing the physical world.
  • Hayden AI — Hayden AI’s mission is to develop cutting-edge artificial intelligence and machine learning technologies that enable the automated enforcement of bus lanes and stops—accelerating public transit, improving street safety, and advancing a more sustainable urban future.
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Greycroft
VC Fund · New York, New York, United States · 48 investments in United States Machine Learning startups

Venture capital and technology investments

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Investment focus

  • Industry: Software, Artificial Intelligence, E-Commerce
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 1031
  • Round size: Seed $1.5M–$8.5M; Series A $3.2M–$24M; Series B $6.2M–$79M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: Likely still investing — raised $451M in 2023

Portfolio highlights

  • Axiom — Axiom is an AI technology company that builds next-generation AI mathematicians.
  • Sapphire Digital — UFABRO situs judi bola dengan keamanan maksimal, enkripsi SSL, transaksi stabil, lisensi terverifikasi, dan layanan yang transparan. Mudah digunakan dan sangat andal.
  • Rocker — Rocker develops a secure, cloud-deployed AI assistant designed to integrate into corporate environments to automate tasks, manage project workflows, and enhance internal collaboration across teams.
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Sequoia Capital
VC Fund · Menlo Park, California, United States · 48 investments in United States Machine Learning startups

We help the daring build legendary companies from idea to IPO and beyond.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Series B, Seed
  • Geography: United States, China, India

Investor stats

  • Total investments: 2614
  • Round size: Seed $1.2M–$14M; Series A $5M–$48M; Series B $11M–$100M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely actively investing — fund raised in 2026

Portfolio highlights

  • Skai — Skai is an AI-powered platform that offers consumer and market insights, strategic planning, omnichannel media activation, testing, and measurement services to brands and retailers. It is the go-to-market engine that enables smarter decisions and better outcomes with actionable intelligence in making customer connections. It includes a suite ofdata-driven products for market intelligence, omnichannel media activation, testing, and measurement, enabling brands and agencies to make predictions, improve strategic planning and drive growth on the most important customer channels.
  • Medallion — Provider credentialing and enrollment reimagined. Accelerate time-to-revenue, stay compliant, and scale provider operations, without adding headcount, through automated credentialing and enrollment.
  • Sourcepulse — Sourcepulse empowers engineering leaders to spot delays early, fix process bottlenecks, and confidently commit to deadlines.
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Bossa Invest
VC Fund · São Paulo, Sao Paulo, Brazil · 47 investments in United States Machine Learning startups, 8 in the past 12 months

Aprenda a Investir em Startups

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Investment focus

  • Industry: Software, Information Technology, Financial Services
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: United States, Brazil, Mexico

Investor stats

  • Total investments: 2119
  • Round size: Seed $166k–$5.8M; Pre-Seed $40k–$1.9M; Venture - Series Unknown $600k–$36M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • FFID — FFID develops AI chatbot platform automating customer communication, lead generation, and marketing workflows.
  • SprayX — Company specialized in interactive process control to evaluate and guarantee the quality of agricultural spraying with excellence. Empowers, leads and monitors applicators in Application Technology tasks.
  • Sandwiche — Sandwiche creates customizable link in bio pages enabling social media monetization and affiliate marketing management.
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SOSV
VC Fund · Princeton, New Jersey, United States · 46 investments in United States Machine Learning startups

SOSV offers pre-seed capital and follow-on financial support to startups focusing on deep technology and scientific innovation. Founders utilize purpose-built laboratory facilities and engineering spaces to accelerate product development and testing. The firm facilitates connections between entrepreneurs and a network of investors through structured matchmaking events and technology summits.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, China, Canada

Investor stats

  • Total investments: 3821
  • Round size: Seed $125k–$5M; Pre-Seed $25k–$1.5M; Convertible Note $50k–$3.6M
  • Lead/follow: 38% lead, 62% follow
  • Last fund: Likely still investing — raised $306M in 2023

Portfolio highlights

  • Halla — Halla Intelligence is a digital solution that leverages over 100 billion shopper and product data points to recommend and promote what grocery items.
  • Verdex Technologies — Verdex Technologies is an advanced materials platform technology that uses nanofibers to disrupt industries. Verdex doesn't just compete, it innovates and disrupts.
  • Samphire Neuroscience — Samphire Neuroscience builds clinically validated neurotechnology to support women across their lives. Our wearable devices, Nettle™ and Lutea™, are built on the same underlying brain-stimulation technology, targeting neural pathways involved in pain, mood, stress, and sleep regulation. - Lutea™ is available globally as a wellness device. Itstimulates the same regions of the brain to support stress regulation, sleep, and recovery - key drivers of readiness and long-term performance - allowing athletes and teams to move beyond wellbeing education alone to practical, evidence-based intervention. - Nettle™ is a CE-marked (EU and UK regulated), drug- and hormone-free device that has been clinically shown to improve pain, mood, functionality, and the ability to train during the menstrual cycle, with measurable benefits after one month of use - supporting athletes to maintain training intensity and movement quality during their period. - The Samphire App is the platform controlling all Samphire hardware products with the use of CycleSync™ AI technology: the only one of its kind to support personalized neurotechnology use for women.
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Madrona
VC Fund · Seattle, Washington, United States · 46 investments in United States Machine Learning startups

A venture capital firm that teams with technology entrepreneurs to nurture ideas from startup to market success.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 578
  • Round size: Seed $1.5M–$15M; Series A $3M–$25M; Series B $6.5M–$75M
  • Lead/follow: 38% lead, 62% follow
  • Last fund: Likely actively investing — fresh fund, raised $5.8M in 2025

Portfolio highlights

  • AdReady — Digital Remedy is an unparalleled digital media company, providing innovative solutions in OTT, CTV, and performance TV advertising. Discover our tools today.
  • Axiom — Axiom is an AI technology company that builds next-generation AI mathematicians.
  • Mercent — Rithum is the connected commerce operations platform helping brands and retailers list, fulfill, and optimize products across every channel.
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Bloomberg Beta
VC Fund · San Francisco, California, United States · 45 investments in United States Machine Learning startups, 16 in the past 12 months

Bloomberg Beta is an early-stage venture capital firm with $450M under management, capitalized solely by Bloomberg. The fund exists to expand Bloomberg’s horizons by investing in companies built by extraordinary founders that make business work better, with a focus on machine intelligence.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 385
  • Round size: Seed $1M–$7.8M; Series A $5M–$25M; Series B $10M–$65M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: Likely actively investing — fresh fund, raised $750M in 2025

Portfolio highlights

  • FluxCap — FluxCap is an AI-powered legal technology company that helps lawyers handle complex litigation and build stronger legal cases. It combines advanced technology with legal expertise to support case strategy, evidence analysis, and legal reasoning. Its mission is to make justice more accessible by helping legal teams take on more high-impact cases.
  • Clay — Clay's spreadsheet helps you find, enrich and act on people and company data from any source - without a line of code. Get started for free, today.
  • Smack Technologies — We're not defense tech tourists. Meet the warfighters, scientists, and engineers building the first Frontier AI Lab for National Security.
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Amplify Partners
VC Fund · Menlo Park, California, United States · 44 investments in United States Machine Learning startups

Amplify is the first investor for technical founders building the next generation of technical applications, tools, and platforms.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 316
  • Round size: Seed $2M–$12M; Series A $6.2M–$30M; Series B $15M–$80M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: Likely actively investing — fresh fund, raised $200M in 2025

Portfolio highlights

  • Arito — Get answers to finance questions instantly. Arito is a self-service analytics platform for accurate insights, automated reports, and decision intelligence.
  • Modal Labs — Modal develops machine learning software to help run code in the cloud. The software enables users to run or deploy machine learning models, massively parallel compute jobs, task queues, web apps, and more. It also writes the code to launch hundreds of custom containers and runs scripts in the cloud faster than on the local machine.
  • Hex Technologies — Rethinking BI Conversational analytics and Context management for the agentic era.
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AME Cloud Ventures
VC Fund · Palo Alto, California, United States · 44 investments in United States Machine Learning startups

AME Cloud Ventures focuses on seed to later stage companies building infrastructure and value chains around data. It specializes in technology-heavy companies gathering or creating unique data at every stage of the data stack — from infrastructure all the way to applications, mobile, and sensors. It strives to find, fund, and support true entrepreneurs. The firm provides a unique and genuine set of resources to our founding teams, from strong operational and business experience to networks of amazing mentors and international partners, particularly in China. AME Cloud Ventures is the venture fund led by Jerry Yang, co-founder of Yahoo!

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 332
  • Round size: Seed $1.1M–$9M; Series A $5.3M–$31M; Series B $12M–$75M
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • OuterSignal — OuterSignal provides AI-driven data enrichment and customer intelligence tailored to ecommerce and digital brands. The platform attaches 100+ demographic, professional, and behavioral signals to each customer record, drawing from publicly available sources such as social profiles, employment data, and online presence. OuterSignal builds detailed personas from this enriched data to help brands segment audiences, identify high-value buyers, and tailor messaging. The product integrates with tools like Slack and Klaviyo so sales, marketing, and lifecycle teams receive alerts and profiles directly in their existing workflows. Use cases include enhancing email lists, personalizing campaigns, prioritizing outreach, and refining lookalike audiences based on real customer attributes.
  • Actualyze AI — Actualyze is an enterprise AI governance platform and AI gateway: separate team access and budget authority, PII guardrails, and one audit trail.
  • Quill Meetings — Meeting notes and next steps, without a bot on the call. Recording and transcription happen on your device.
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Ulu Ventures
VC Fund · Palo Alto, California, United States · 44 investments in United States Machine Learning startups, 7 in the past 12 months

With deep connections to Stanford and Silicon Valley, Ulu Ventures is a venture capital firm that actively seeks and funds women and diverse founder teams.

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Investment focus

  • Industry: Software, Financial Services, FinTech
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Mexico, Singapore

Investor stats

  • Total investments: 469
  • Round size: Seed $1M–$7.2M; Pre-Seed $150k–$3.7M; Series A $3.2M–$33M
  • Lead/follow: 16% lead, 84% follow
  • Last fund: Likely still investing — raised $208M in 2024

Portfolio highlights

  • Meadow AI — Meadow AI is developing the retail and restaurant industries' operational brains. Our multimodal AI platform transforms POS, audio, and camera data into insights and actions in real time.
  • Allswell — Allswell is a queer-founded mental health platform dedicated to making affirming, accessible care available to the LGBTQ+ community, covered by Medicaid & major insurance.
  • TerraBlaster — TerraBlaster is a cutting-edge agricultural technology firm focused on transforming sustainable agriculture through enhanced automation and precise technologies.
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Bain Capital Ventures
VC Fund · San Francisco, California, United States · 43 investments in United States Machine Learning startups

Bain Capital Ventures helps founders build iconic businesses that transform the way we live and work.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 882
  • Round size: Seed $2M–$8.1M; Series A $5.2M–$34M; Series B $10M–$62M
  • Lead/follow: 43% lead, 57% follow
  • Last fund: Likely still investing — raised $1.9B in 2023

Portfolio highlights

  • Polars — Polars is the fastest open-source DataFrame library for Python and Rust, and the framework that takes the same query from a laptop to the cloud.
  • MedeAnalytics — Enhance health outcomes and reduce costs through effective healthcare data analytics that provide actionable insights and clarity.
  • ZeroTurnaround — ZeroTurnaround is a small, fast-growing start-up based in Tartu, Estonia. The company is the creator of JRebel, an award-winning Java development productivity tool.JRebel a JVM plugin that eliminates the build and redeploy phases of the J2E development cycle.Based on a survey completed in 2010 from over 1100 J2E developers, it was discoveredthat between 10 - 23% of each development hour is spent on turnaround. Turnaround is the time it takes for the changes in code to propagate to the running application. It includes build time, deploy time and initialization time.JRebel monitors Java classes and reloads the changes in real-time without restarting your application or losing any state. It does not require a debug mode and, unlike built-in JVM HotSwap, supports class schema changes like adding methods or fields.
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Lux Capital
VC Fund · New York, New York, United States · 43 investments in United States Machine Learning startups

Lux Capital focuses on sectors such as artificial intelligence, biotechnology, advanced materials, space, and energy, backing businesses that apply scientific research to commercial applications. It provides capital alongside strategic input on product development, company building, and long-term positioning. The firm works with technical founders and research-driven teams to translate complex innovations into scalable businesses. It evaluates opportunities based on the underlying science, potential for industry impact, and feasibility of execution over extended time horizons.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 724
  • Round size: Seed $1.5M–$30M; Series A $7M–$90M; Series B $13M–$150M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely actively investing — fresh fund, raised $10M in 2026

Portfolio highlights

  • Adimab — Premier Human Antibody Discovery and Optimization
  • Reflex — The open-source framework to build and deploy web apps using Python.
  • Cajal Neuroscience — Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease.
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Streamlined
VC Fund · San Francisco, California, United States · 42 investments in United States Machine Learning startups, 13 in the past 12 months

We partner with seed-stage founders to build exceptional companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Mexico, Colombia

Investor stats

  • Total investments: 401
  • Round size: Seed $1M–$9.2M; Series A $4M–$24M; Series B $7M–$68M
  • Lead/follow: 52% lead, 48% follow
  • Last fund: Likely still investing — raised $20M in 2024

Portfolio highlights

  • a1Mobile — Your carrier, now AI-native.
  • BioStack — BioStack Platforms develops data infrastructure and simulation environments for healthcare and drug discovery AI. The company builds proprietary preclinical and clinical data pipelines that connect longitudinal, multimodal medical data such as EHRs, imaging, ECGs, labs, notes, audio, and outcomes. It structures this information intomachine-learning-ready datasets and workflow-aligned simulation environments rather than static text corpora. These environments support post-training, reinforcement learning, and multi-agent reasoning for medical AI systems. BioStack Platforms serves AI labs, biotechnology startups, pharmaceutical teams, and data providers that need domain-specific datasets, causal inference support, and robust reward models. Its offerings are used to test, evaluate, and train medical AI models on real-world clinical workflows before deployment in practice.
  • Flagler Health — Flagler Health is the AI-native operating system for musculoskeletal (MSK) care. Flagler seamlessly coordinates clinical and administrative workflows across the full patient lifecycle inside providers' existing EMRs.
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Eniac Ventures
VC Fund · New York, New York, United States · 41 investments in United States Machine Learning startups, 15 in the past 12 months

Eniac Ventures is a venture capital firm that focuses its seed-stage investments in technology, software, robotics, and SaaS startups. The firm partners with bold founders to help them achieve product-market fit and grow their companies from inception to success. With each fund, the approach of Eniac Ventures has evolved and expanded to address the growing needs of portfolio companies. Founders are encouraged to focus on their product, which led to the creation of the Eniac Platform. Term sheets represent just the initial step; companies partnering with Eniac benefit from a range of complimentary support services. These include access to a talent recruiter dedicated to finding top employees, particularly in engineering, as well as a public relations and marketing specialist to help products reach key audiences from launch through growth. Additionally, operational resources are provided to help organize staff and implement best practices. Business development and networking opportunities are available with thousands of leading companies, investors, and brands. Furthermore, connections to other founders within Eniac’s portfolio facilitate the exploration of synergies and opportunities. Fundraising support encompasses guidance on pitch decks, strategies for follow-on investors, and syndicate building.

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Investment focus

  • Industry: Software, Artificial Intelligence, Mobile
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Spain

Investor stats

  • Total investments: 775
  • Round size: Seed $1.1M–$5.5M; Series A $6.5M–$20M; Series B $5M–$40M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: Likely still investing — raised $12M in 2024

Portfolio highlights

  • GenHealth.ai — GenHealth.ai provides healthcare solutions using generative AI trained on encoded medical events. Its product is a generative healthcare AI publicly available. It includes a foundation transformer model (new neural networks with excellent memory), an API, and user applications that can generate and predict future sequences of health events usinghistorical events. Together they can be used to build a large variety of customized applications.
  • Dynamic Creatures — Dynamic Creatures creates responsive character robots for the entertainment and service sectors.
  • Nebex — NEBEX is a successful middle market investment intermediary. NEBEX, has completed over 100 transactions throughout the United States. New England Business Exchange concentrates on representing sellers whose business appeals to large corporate buyers or private equity groups.
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BoxGroup
VC Fund · New York, New York, United States · 40 investments in United States Machine Learning startups

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 965
  • Round size: Seed $1.5M–$9.2M; Series A $3.5M–$31M; Series B $15M–$100M
  • Lead/follow: 5% lead, 95% follow
  • Last fund: Likely actively investing — fresh fund, raised $275M in 2025

Portfolio highlights

  • Scuba — Scuba is an AI-powered shared context engine and productivity platform built to serve as a unified "shared memory" for teams and their digital AI agents.
  • Firefly — Firefly provides an integrated safety platform that helps organizations manage daily operations and emergency response through software and hardware solutions. Its Ember Safety Platform combines cloud-based tools like AI-driven mapping, mass communications, and emergency service integration with physical devices such as panic buttons, gunshot detection, and readiness systems. The platform supports tailored safety workflows that streamline procedures and improve situational awareness across different environments. Firefly’s onboarding process includes generating 3D site maps and connecting existing infrastructure to enable protocol customization and real-time alerting. The company’s offerings aim to unify safety functions in a single system that assists teams in coordinating actions from routine tasks to urgent incidents.
  • Funnel — Our revolutionary CRM property management software saves both time and money for agents and owners while making leasing more efficient.
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First Round Capital
VC Fund · San Francisco, California, United States · 40 investments in United States Machine Learning startups

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 995
  • Round size: Seed $1.2M–$9M; Series A $3M–$26M; Series B $7M–$63M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $296M in 2020

Portfolio highlights

  • Actively — Actively is custom-built AI for GTM teams.
  • Serval — Serval is the AI-native ESM that automates employee requests, onboarding/offboarding, just-in-time access, and more.
  • Mach9 — Mach9 is building the operating system for cities. We're monitoring surface and underground infrastructure to predict and prevent infrastructure failures.
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Intel Capital
VC Fund · Santa Clara, California, United States · 39 investments in United States Machine Learning startups

Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, Israel

Investor stats

  • Total investments: 1294
  • Round size: Series A $4.5M–$30M; Series B $7M–$53M; Series C $7M–$90M
  • Lead/follow: 36% lead, 64% follow

Portfolio highlights

  • YuMe — YuMe is a provider of digital video brand advertising solutions that drives inventory monetization and enables advertisers to reach targeted audiences across a wide range of internet-connected devices. Designed to serve the specific needs of brand advertising, its technology platform simplifies the complexities associated with delivering effectivedigital video advertising campaigns in today’s market.YuMe was founded in 2004 by
  • Azure Solutions — Azure Solutions is the world's largest revenue assurance company. It is headquartered in London, UK, with employees in Westminster (Colorado), Ipswich, Paris, Frankfurt, Madrid, Barcelona, Islamabad, Kuala Lumpur, Jakarta, Singapore, Sydney, Melbourne and Mexico City. Azure's end-to-end revenue-assurance product portfolio forcurrent-generation networks includes Data Integrity, Wholesale and Interconnect Billing, International Settlements, Fraud Management, Mediation, Management, Translation and Rating, Event Integrity and Route Optimisation.
  • FlatFrog Laboratories — Free online whiteboard that is easy to use on your personal laptop or walk-up and use as a digital whiteboard on your InGlass meeting room display. Use FlatFrog Board across your entire Microsoft Teams workspace.
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Founders Fund
VC Fund · San Francisco, California, United States · 37 investments in United States Machine Learning startups

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 1102
  • Round size: Seed $1.6M–$15M; Series A $5.5M–$45M; Series B $15M–$100M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely actively investing — fresh fund, raised $6B in 2026

Portfolio highlights

  • Quantcast — We are taking an entirely new approach to advertising on the open internet.
  • Coherence Neuro — Opto Biosystems specializes in the development of innovative healthcare technologies that bridge the gap between cancer neuroscience and bioelectronics. The company focuses on creating smaller, softer, and wireless biological interfaces designed to offer a new treatment modality. By leveraging advancements in neural engineering and bioelectronics,Opto Biosystems is dedicated to building new tools that interface with the body, aiming to improve patient outcomes in the healthcare sector. Their work includes exploring the stability of thin-film electrodes for neuromodulation, highlighting their commitment to advancing medical technology.
  • Watchtower Labs — Watchtower Labs is an AI-first team with a single mission: to solve the most difficult technical obstacles in vital simulations and defense.
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Kleiner Perkins
VC Fund · Menlo Park, California, United States · 37 investments in United States Machine Learning startups, 67 in the past 12 months

Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 1423
  • Round size: Series A $5M–$50M; Series B $10M–$75M; Series C $13M–$110M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: Likely actively investing — fresh fund, raised $58M in 2026

Portfolio highlights

  • Aries — an open platform for traders, investors, and developers
  • Modal Labs — Modal develops machine learning software to help run code in the cloud. The software enables users to run or deploy machine learning models, massively parallel compute jobs, task queues, web apps, and more. It also writes the code to launch hundreds of custom containers and runs scripts in the cloud faster than on the local machine.
  • Flapping Airplanes — Flapping Airplanes is an artificial intelligence research lab that focuses on advancing foundational AI technologies with an emphasis on data-efficient model development and fundamental research into next-generation learning approaches. The organization’s work centers on exploring alternative training paradigms that reduce dependency on massivedatasets and compute scale, aiming to enable systems that learn with efficiency more akin to human cognition rather than brute-force training methods. Its team includes researchers and technical experts pursuing long-horizon scientific challenges in AI architecture, training mechanisms, and algorithmic innovation. Flapping Airplanes engages with investors and collaborators to support its research agenda, backing efforts that expand the theoretical and practical frontiers of artificial intelligence without immediate commercial product constraints. While the lab operates primarily as a research-first initiative, its findings are intended to inform future applications in areas such as enterprise AI, robotics, scientific discovery, and decision systems. The company’s strategy reflects a shift away from traditional scale-focused AI development toward exploring deep, principled advances in learning efficiency and model capabilities.
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Village Global
VC Fund · San Francisco, California, United States · 37 investments in United States Machine Learning startups, 14 in the past 12 months

Early stage venture capital backed by some of the world's best entrepreneurs.

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Investment focus

  • Industry: Software, Artificial Intelligence, Financial Services
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 515
  • Round size: Seed $1.5M–$10M; Pre-Seed $250k–$3.5M; Series A $7M–$23M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: May invest from a new fund soon — raised $125M in 2021

Portfolio highlights

  • Legato Audio — Legato Hearing develops stylish glasses with built-in hearing technology, offering a discreet alternative to traditional hearing aids.
  • Cast Insights — Cast Insights is an AI-powered platform that turns global spoken content—TV, radio, podcasts, livestreams—into structured, searchable real-time intelligence for investors, policy teams, strategists, and newsrooms.
  • General Compute — General Compute provides an ASIC-based cloud inference platform focused on running AI inference workloads. The company offers an OpenAI-compatible API that allows users to access hosted large language models and switch from existing GPU-based providers by changing the base URL and API key. It supports deploying both its own supported models andcustomer-supplied models on its infrastructure, emphasizing high token throughput and low time to first token. General Compute also offers dedicated custom deployments with service-level agreements, custom scaling, and guaranteed capacity for production workloads. Its infrastructure targets use cases such as AI agents, coding assistants, and real-time voice applications that require low-latency, high-throughput inference.
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Hyperplane
VC Fund · Boston, Massachusetts, United States · 36 investments in United States Machine Learning startups

Hyperplane Venture Capital is an investment firm focused on exceptional founders building machine intelligence and data companies. They partner with exceptional founders who are leveraging machine intelligence, sensor technology, and cloud computing to solve the world’s hardest problems uncovering the underlying structure for each problem and creating solutions at the nexus of perception, communication, intelligence, and insight. The company was founded by Vivjan Myrto, John Murphy and Brendan Kohler in 2015; and is headquartered in Boston, Massachusetts.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 117
  • Round size: Seed $1.5M–$6.5M; Series A $4.5M–$24M; Series B $15M–$54M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: May invest from a new fund soon — raised $8M in 2021

Portfolio highlights

  • Modulate — Modulate uses revolutionary machine learning to proactively detect and escalate toxic behavior in your game. ToxMod becomes an expert in your code of conduct and empowers your moderators to make the right decisions to protect your community from the worst behavior happening in voice chat in real time.
  • MedEssist — The complete business solution for community pharmacies.
  • Integrate — The only program management tool built specifically for multi-team hardware development.
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Everywhere Ventures
VC Fund · New York, New York, United States · 36 investments in United States Machine Learning startups

Everywhere Ventures is a global pre-seed venture capital fund for founders, by founders. Click to read Everywhere VC, by Everywhere Ventures, a Substack publication with tens of thousands of subscribers.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, United Kingdom, Australia

Investor stats

  • Total investments: 1308
  • Round size: Seed $1M–$6.5M; Pre-Seed $250k–$2.5M; Series A $6M–$20M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $4.4M in 2026

Portfolio highlights

  • Donna — Meet Donna, the AI assistant built for field sales teams. Save time, cut admin, and close more deals with less effort.
  • Netsec — Professional cybersecurity and managed IT services to protect your business 24/7.
  • Electric Plant Company — We are a plant intelligence company transforming plant care today and accelerating the techno-biophillic future of tomorrow.
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Sierra Ventures
VC Fund · San Mateo, California, United States · 36 investments in United States Machine Learning startups

Sierra Ventures is an early-stage venture capital firm investing in the future of enterprise, healthcare, infrastructure, and more.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: United States, China, Canada

Investor stats

  • Total investments: 423
  • Round size: Seed $2M–$11M; Series A $5M–$21M; Series B $5.7M–$38M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — raised $266M in 2023

Portfolio highlights

  • Eden — Eden unifies medical imaging operations with clinical AI: PACS, teleradiology, AI-assisted diagnosis and structured reporting, deployed across 2,600+ imaging departments.
  • Razorsight — Razorsight's Cloud-based Predictive Analytics Software is used by the world's best known telecom brands to improve profits including AT&T, Verizon, T-Mobile, Telus, Tata, Orange, CenturyLink, Windstream, IBM, Comcast and Facebook. Razorsight analyzes network and subscriber activities to control costs, predict churn, and deliverreal-time insights into customer and network activity. These insights are operationalized to improve margins via revenue growth, retention and cost reduction.
  • TrustedRouter — TrustedRouter develops an independent API router and intelligent architecture that protects privacy through an attested gateway.
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Bessemer Venture Partners
VC Fund · Redwood City, California, United States · 36 investments in United States Machine Learning startups

Bessemer Venture Partners is a venture capital firm that invests in early-stage and growth-stage companies across technology, healthcare, and consumer sectors. It provides capital to startups and emerging businesses while supporting founders with strategic guidance, operational insight, and network access. The firm participates in multiple funding stages, from seed investments to later growth rounds, and works closely with portfolio companies on product development, market expansion, and organizational scaling. Its investment activities span software, cloud infrastructure, fintech, biotech, and internet-enabled businesses, aligning capital deployment with long-term company building.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, India, Israel

Investor stats

  • Total investments: 1785
  • Round size: Series A $5M–$43M; Series B $10M–$60M; Series C $12M–$101M
  • Lead/follow: 38% lead, 62% follow
  • Last fund: Likely actively investing — fresh fund, raised $1B in 2025

Portfolio highlights

  • Stromedix — sohibslot merupakan situs slot gacor 4d dengan server thailand yang terkenal gampang menang di tahun 2026, deposit withdraw cepat, akses cepat dan stabil.
  • Valence — Work better. Together.
  • Simply Measured — Reimagine how social media can grow your business with Sprout Social. See our social media management tools in action. Start your own free trial today.
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8VC
VC Fund · San Francisco, California, United States · 35 investments in United States Machine Learning startups

8VC focuses its investment activities on industries such as life sciences, healthcare, logistics, manufacturing, enterprise software, and defense. Its portfolio support model aids founders in scaling transformational technologies intended to create long-term economic and societal value. The firm actively finances breakthroughs ranging from medical innovations and zero-emission transit models to security compliance and infrastructure automation.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 687
  • Round size: Seed $2.5M–$13M; Series A $8M–$56M; Series B $17M–$175M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely actively investing — fresh fund, raised $45M in 2026

Portfolio highlights

  • Dren Bio — Dren Bio is a biotechnology company with a portfolio of attractive projects focused on powerful protein engineering technologies for the depletion of cells, protein aggregates, and other disease-causing agents. It is a holding company business model aimed at creating value with multiple projects as stand-alone assets.
  • Fragment — Fragment automates complex, exception-heavy procurement workflows with AI agents.
  • Hello Patient — Healthcare AI that gets your team off the phone & in front of patients
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Gradient
VC Fund · Mountain View, California, United States · 34 investments in United States Machine Learning startups, 40 in the past 12 months

Gradient is the seed fund designed for founders in AI.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, The Netherlands, Germany

Investor stats

  • Total investments: 396
  • Round size: Seed $2.6M–$10M; Series A $8.2M–$28M; Series B $22M–$58M
  • Lead/follow: 50% lead, 50% follow
  • Last fund: Likely actively investing — fresh fund, raised $220M in 2026

Portfolio highlights

  • Sava — Sava offers an AI-powered platform that automates trust setup, funding, and administration.
  • Pathfinder AI — Pathfinder AI provides psychometric assessments, career counseling, and admission guidance to help students explore and plan their futures.
  • Collective — Collective offers financial solutions designed for self-employed business owners - company formation, tax, accounting & bookkeeping.
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Pear VC
VC Fund · Palo Alto, California, United States · 34 investments in United States Machine Learning startups, 48 in the past 12 months

Pear VC partners with entrepreneurs from day zero to build category-defining companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Brazil, Colombia

Investor stats

  • Total investments: 541
  • Round size: Seed $1.4M–$8.5M; Pre-Seed $175k–$3.5M; Series A $8M–$40M
  • Lead/follow: 18% lead, 82% follow
  • Last fund: Likely still investing — raised $3.4M in 2024

Portfolio highlights

  • Presonance — Presonance provides brain-based creative testing for agencies and research partners. Its platform simulates audience responses to videos, images, and scripts to assess how creative content may influence viewer behavior. Users can analyze audience responses moment by moment and use the results to evaluate and refine campaigns before launch. Presonance also provides sample analyses and research-backed insights for creative testing.
  • Phinity Labs — Phinity Labs builds AI systems designed to fully automate the entire silicon microchip engineering process, spanning from original architectural concepts to final manufacturing preparation.
  • Hertha Metals — At Hertha Metals, we are developing advanced steel solutions to accelerate the growth and global competitiveness of the U.S. steel industry.
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Cultivation Capital
VC Fund · St Louis, Missouri, United States · 34 investments in United States Machine Learning startups

Cultivation Capital invests in young companies whose ideas have potential to transform the way we live and work.

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Investment focus

  • Industry: Software, Health Care, SaaS
  • Stage:Seed, Series A, Venture - Series Unknown
  • Geography: United States, Australia, Canada

Investor stats

  • Total investments: 339
  • Round size: Seed $500k–$5M; Series A $1.4M–$15M; Venture - Series Unknown $475k–$10M
  • Lead/follow: 62% lead, 38% follow
  • Last fund: Likely actively investing — fresh fund, raised $6.5M in 2025

Portfolio highlights

  • My FLiiP — FLiiP is the gym management software trusted by gyms in Canada and beyond. It unifies CRM, member management, billing, a branded app, and AI on one platform, the smart way to grow your gym, not just manage it.
  • Force Equals — Force Equals is a Multi Agent AI planning operating system for enterprise software, ai, and business project planning. Manage Idea flow, Portfolio, Define challenges, align your team, collaborate, uncover the hidden requirements, and seamlessly hand off to development, project management or procurement workflows.
  • Corstasis Therapeutics — Esperion is dedicated to discovering, developing and commercializing innovative and combination medicines to reduce cardiovascular risk.
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Uncork Capital
VC Fund · San Francisco, California, United States · 33 investments in United States Machine Learning startups

For more than 20 years, Uncork has focused on one stage: seed. Our partners have invested in over 290 companies, with more than 100 meaningful outcomes and $60B+ in enterprise value created — including Fitbit (NYSE: FIT, Google), Sendgrid (NYSE: SEND, Twilio), Eventbrite (NYSE: EB), Poshmark (NASD: POSH), and Postmates (UBER), as well as fast-growing startups like [Loft Orbital](https://loftorbital.com/), [LaunchDarkly,](https://launchdarkly.com/) [Human Interest](https://humaninterest.com/), [Gamma](https://gamma.app/), [GPTZero](https://gptzero.me/), [Tailscale](https://tailscale.com/), [Numeral](https://www.numeral.io/), [Ivo](https://www.ivo.ai/), [Coder](https://coder.com/), [Anything](https://www.anything.com/), [Hallow](https://hallow.com/), [ClassDojo](https://www.classdojo.com/), [Wrapbook](https://www.wrapbook.com/), and [Carrot Fertility](https://www.get-carrot.com/). We invest in companies using AI and emerging technologies to create leverage, unlock scale, and push industries forward. We're typically the first major check on the cap table, often leading seed rounds with an initial investment of $3M-$5M. We keep terms simple and transparent, because a clean term sheet makes a strong partnership. We look for team, TAM, and tailwinds, but conviction in founder–market fit comes above all else. We back founders who bring sharp insight into their markets and the drive to build what others can’t yet see. There’s no single playbook for building a company. Every journey looks different, but our role stays the same: a steady partner who shows up early, knows when to deliver hard truths, and stays engaged long after the round closes. Learn more at [uncorkcapital.com](http://uncorkcapital.com/) or follow along on [LinkedIn](https://www.linkedin.com/company/uncorkcapital/) and [X](https://x.com/uncorkcap).

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Investment focus

  • Industry: Software, SaaS, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 520
  • Round size: Seed $1.3M–$6M; Series A $3M–$18M; Series B $10M–$50M
  • Lead/follow: 22% lead, 78% follow
  • Last fund: Likely actively investing — fresh fund, raised $75M in 2025

Portfolio highlights

  • Bacca.ai — Bacca is an AI engineer that takes full responsibility for your software after you ship it.
  • Evos — Evos is an AI-powered operations platform designed to transform how companies run their internal processes by turning manual workflows into autonomous, intelligence-driven systems. The platform is positioned for industries like logistics, manufacturing, energy, real estate, telecom, and retail, where operations teams are often overloaded with repetitive, multi-system tasks. A key focus is eliminating inefficiencies such as exception handling, coordination across multiple platforms, and manual data processing.
  • Phinity Labs — Phinity Labs builds AI systems designed to fully automate the entire silicon microchip engineering process, spanning from original architectural concepts to final manufacturing preparation.
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Felicis
VC Fund · Menlo Park, California, United States · 32 investments in United States Machine Learning startups

Backing founders building iconic companies that transcend boundaries

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 740
  • Round size: Seed $1.2M–$14M; Series A $4.5M–$42M; Series B $10M–$75M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: Likely actively investing — fresh fund, raised $900M in 2025

Portfolio highlights

  • Lumaril — Lumaril is a software company that develops an artificial intelligence platform for optimizing physical production operations. The company connects its platform to existing industrial control systems and uses operational data, audio and visual sensors, artificial intelligence, and machine learning to model facility performance in real time. Its platform determines operational adjustments and can autonomously modify set points, control logic, and coordination to improve production throughput and yield. Lumaril serves industrial facilities in manufacturing, chemicals, biologics, and oil and gas. The company applies AI-driven automation to existing industrial infrastructure without requiring replacement of established control systems. Its technology is designed to support continuous optimization of complex production environments.
  • Arda — Arda is an AI manufacturing software startup founded by Bob McGrew.
  • Sooth Labs —
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Greylock
VC Fund · Menlo Park, California, United States · 32 investments in United States Machine Learning startups, 35 in the past 12 months

Greylock Partners is a leading venture capital firm based in Silicon Valley. We are early partners of remarkable teams building companies that matter.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Israel, United Kingdom

Investor stats

  • Total investments: 984
  • Round size: Seed $1.2M–$11M; Series A $5.1M–$40M; Series B $11M–$62M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely actively investing — fresh fund, raised $1.5B in 2026

Portfolio highlights

  • SuperMe — SuperMe brings the experience of people who've done it into your work. Think it through with them, and let your own work speak for itself.
  • Snorkel AI — Snorkel AI builds specialized training data, benchmarks, and evaluation environments that help frontier models and agents perform in high-stakes domains.
  • Lightfield — Lightfield is an AI-native CRM for companies to capture, analyze, and understand everything about their customers.
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Two Sigma Ventures
VC Fund · New York, New York, United States · 32 investments in United States Machine Learning startups

We are an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power to change the world.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 281
  • Round size: Seed $1.4M–$8M; Series A $6.9M–$70M; Series B $14M–$120M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — raised $400M in 2022

Portfolio highlights

  • Osmo — Giving computers a sense of smell.
  • Swarm Aero — Swarm empowers small teams to mobilize thousands of uncrewed vehicles in communications-limited, contested environments.
  • Artemis — Artemis is the first protective layer that is AI-native
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Index Ventures
VC Fund · San Francisco, California, United States · 31 investments in United States Machine Learning startups

Index Ventures is an international venture capital firm with dual headquarters in San Francisco and London, investing in technology-enabled companies with a focus on e-commerce, fintech, mobility, gaming, infrastructure/AI, and security.

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Investment focus

  • Industry: Software, Artificial Intelligence, E-Commerce
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 1635
  • Round size: Seed $1.3M–$16M; Series A $5M–$35M; Series B $12M–$102M
  • Lead/follow: 43% lead, 57% follow
  • Last fund: Likely actively investing — fresh fund, raised $400M in 2026

Portfolio highlights

  • PanGenetics — PanGenetics B.V. develops monoclonal antibodies for the treatment of immune mediated diseases.PanGenetics is a clinical development company that specializes in taking antibodies from the late research stage through to clinical proof of concept. The company is based in Utrecht, the Netherlands with an office in Cambridge, UK. PanGenetics employsa lean business model with manufacturing and clinical development activities outsourced to specialist providers. Apart from PG110, the other clinical program of PanGenetics is PG102, a CD40 antagonist for treatment of autoimmune diseases which is currently being evaluated in a clinical study in psoriatic arthritis patients
  • Acutus Medical — Acutus Medical develops medical technologies to treat complex cardiac arrhythmia. The company's platform displays the heart’s true activation pattern, turning the chaos of a complex arrhythmia into a clear vision for electrophysiologists.Acutus Medical is a privately funded company founded in 2011 and based in Carlsbad, California. Itsproducts are co-developed in the U.S. and Europe with an exceptional team of medical scientists, biomedical engineers, and other professionals.It was founded in 2011 and headquartered in Carlsbad, California.
  • Milestone Systems — See and know more with video technology. Milestone offers award-winning XProtect video management software, Arcules VSaaS, and BriefCam analytics.
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Homebrew
VC Fund · San Francisco, California, United States · 31 investments in United States Machine Learning startups, 10 in the past 12 months

Homebrew works with mission-driven teams developing technology products and services across multiple industries, with a focus on helping startups navigate seed and early growth stages. Homebrew provides operational guidance, investor collaboration, and introductions to customers, partners, and subject matter experts to support business execution and decision-making. Its investment approach emphasizes long-term founder relationships, board development, data-informed problem solving, and continued participation in later funding rounds when aligned with company growth.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Mexico, Brazil

Investor stats

  • Total investments: 255
  • Round size: Seed $1.5M–$8.5M; Series A $7M–$25M; Series B $9.5M–$50M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely still investing — raised $50M in 2024

Portfolio highlights

  • Portola — Portola develops the Tolan app, an AI companion that features animated alien personalities for conversational support. The platform matches users with a personalized virtual friend through a personality interview, then evolves that relationship via memory and daily reflection, helping users feel more grounded amid modern pressures. Tolan engages invoice-based chat and can analyze images, enabling natural, context-aware interactions.
  • Scuba — Scuba is an AI-powered shared context engine and productivity platform built to serve as a unified "shared memory" for teams and their digital AI agents.
  • Peppermint — Peppermint provides financial operations software for clinical research sites, focusing on managing billing, reconciliation, and accounts receivable processes related to clinical trials. The platform connects with existing clinical trial management systems (CTMS) and accounting tools to collect visit, contract, invoice, and payment data without requiring research teams to change their workflows. It validates trial activity against sponsor contracts, identifies discrepancies, and helps prepare invoices while maintaining an audit trail tied to specific study visits and payments. Peppermint also gives research networks visibility into outstanding sponsor payments and receivables through real-time financial tracking across studies and sites. Its integrations include systems such as CRIO, Veeva, RealTime, QuickBooks, NetSuite, and Sage Intacct, allowing organizations to consolidate financial records from multiple operational platforms.
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Foundation Capital
VC Fund · Palo Alto, California, United States · 31 investments in United States Machine Learning startups

For 30 years we've backed extraordinary founders from day zero.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Mexico, Canada

Investor stats

  • Total investments: 820
  • Round size: Seed $1.6M–$10M; Series A $6M–$30M; Series B $6M–$60M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: Likely still investing — raised $600M in 2023

Portfolio highlights

  • Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
  • Cyphort — Cyphort has developed Next Generation Distributed Software Platform to provide the broadest enterprise visibility and accurate detection of advanced threats & evasion techniques, and zero-day attacks by utilizing behavioral analytics, machine learning, and Long-Data Security-Analytics.Cyphort's innovative approach detects the mostadvanced threats through a highly accurate platform combined with validation and prioritization of threats in context of the organizations eco-system. Through this process Cyphort produces highly customized Actionable Intelligence to users.The Cyphort Distributed Platform has been build with flexibility allowing for seamless integration and detection not only at the edge and network layers but also in virtual infrastructures, cloud environments, and mobile platforms.
  • Fulcrum — One AI platform for the entire account lifecycle, from prospecting to renewal, built into the systems your team already uses.
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Machine Learning Investor funding in United States at a glance

Stats across 11k deals from 11k investors.

11k
investors
in United States Machine Learning startups
11k
deals
in United States Machine Learning startups
$3.5M
median round
in United States Machine Learning startups
30%
lead investors
lead at least one round
30%
Seed
most common funding stage
71/29
VC / Angel
share of investor count

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