Top 50 Software Startup Investors in United States (November 2026)

Portfolio highlights

• Athel AI — Athel AI provides an AI-powered clinical intake platform for physicians and healthcare teams. Its tools conduct patient interviews through voice, chat, and video, capture clinical histories, and generate structured summaries for physicians. The platform also supports AI-assisted reception, dictation, multilingual interviews, and automated clinical workflows. Athel AI provides clinical decision support while keeping diagnosis and treatment decisions under the physician's authority.
• Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
• TasksMind — tasksmind turns urgent but ambiguous bug reports into fixed code and customer follow-up, so bugs don't become churn.

Portfolio highlights

• NextDroid — NextDroid - We're Doing Something Different
• Hello Patient — Healthcare AI that gets your team off the phone & in front of patients
• Alva Energy — Alva Energy is a nuclear solution based firm that aids challenges related to nuclear power offering on time delivery of nuclear megawatts.

Portfolio highlights

• Hyperpublic — Hyperpublic is an open database of people, places, and things tied to a specific location. Anyone can add objects to the database and developers will be able to build applications on top of the data.
• Dream — Dream Technologies develops generative AI software for home and interior design. The company offers Dream, a platform that converts residential ideas into detailed, construction-ready architectural plans. Its tools help property owners and designers move from abstract concepts to precise layouts tailored to specific spaces and use patterns. The platform uses interactive 3D graphics and custom machine learning models to manage visualization, spatial layout, and structural planning. Dream Technologies focuses on streamlining design workflows for both consumer and commercial home design projects.
• Daletlabs — Dalet Labs is pioneering the future of e-commerce through Generative AI and visual product discovery. Its platform transforms AI-generated imagery into interactive shopping experiences featuring real, purchasable products. By combining creativity, personalization, and technology, Dalet Labs is redefining how consumers discover and shop for products.

Portfolio highlights

• Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
• Stoïk — Stoïk is a cyber insurance company that integrates cybersecurity software with insurance protection, helping businesses manage their cyber risks effectively. Stoïk empowers brokers by offering clients comprehensive insurance policies and protection against cyber risks. Its mission is to equip brokers with the tools to help their clients insure andsafeguard against cyber threats.Stoïk's unique product simplifies the underwriting process using automated tests, replacing traditional questionnaires. It also provides continuous risk prevention through integrated cybersecurity tools and ensures swift, effective incident response with an in-house team of crisis management experts.
• Supersonik — Supersonik provides an AI-powered platform for SaaS companies to offer 24/7 interactive product demos, enabling prospects to explore and personalize demos instantly without scheduling or manual intervention.

Portfolio highlights

• Lemonade — Lemonade operates as a full-stack insurance company powered by AI and behavioral economics and driven by social good. It is a licensed insurance carrier, offering homeowners and renters insurance. Lemonade replaces brokers and bureaucracy with bots and machine learning, delivering zero paperwork and instant everything. The company uses artificialintelligence and behavioral economics to set rates for the homes and renters it insures. Lemonade was founded in Tel Aviv, Israel, in 2015 and is headquartered in New York, NY, United States.
• Datalogix — Datalogix® is the industry-recognized leader at connecting digital media and offline purchasing data. We help more than half of the top 100 consumer marketers increase the effectiveness and measurability of their advertising. DLX Platform®, encompasses over $1 trillion in consumer spending and powers campaigns for more than 75% of online mediacompanies. DLX ROI® is rapidly becoming the industry standard for measuring offline sales lift for digital media. Datalogix also offers predictive analytics for Direct Mail, and integrated media solutions via the DLX Net. Our expertise spans the major consumer segments, including Retail, CPG, Automotive, Telecom, Travel and Financial Services. We are based in Colorado, with offices in New York City, San Francisco, Boston, Chicago, Detroit, and London.
• Ayr Energy — Ayr Energy designs, engineers, manufactures, and supplies power transformers, distribution transformers, switchgear, and circuit breakers.

Portfolio highlights

• Albedo — Aerial quality imagery - from space.
• Eden — Eden unifies medical imaging operations with clinical AI: PACS, teleradiology, AI-assisted diagnosis and structured reporting, deployed across 2,600+ imaging departments.
• Kivo Health — Kivo Health is a telehealth lung care company that provides rehab for chronic lung disease.

Portfolio highlights

• Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
• Whizzo — Whizzo specializes in materials science-driven manufacturing of engineered fashion and technical textiles. Our expertise lies in creating and executing innovative textile blends tailored for applications across automotive, agriculture, medical textiles, and engineered fashion.
• Daletlabs — Dalet Labs is pioneering the future of e-commerce through Generative AI and visual product discovery. Its platform transforms AI-generated imagery into interactive shopping experiences featuring real, purchasable products. By combining creativity, personalization, and technology, Dalet Labs is redefining how consumers discover and shop for products.

Portfolio highlights

• Skai — Skai is an AI-powered platform that offers consumer and market insights, strategic planning, omnichannel media activation, testing, and measurement services to brands and retailers. It is the go-to-market engine that enables smarter decisions and better outcomes with actionable intelligence in making customer connections. It includes a suite ofdata-driven products for market intelligence, omnichannel media activation, testing, and measurement, enabling brands and agencies to make predictions, improve strategic planning and drive growth on the most important customer channels.
• Medallion — Provider credentialing and enrollment reimagined. Accelerate time-to-revenue, stay compliant, and scale provider operations, without adding headcount, through automated credentialing and enrollment.
• Sourcepulse — Sourcepulse empowers engineering leaders to spot delays early, fix process bottlenecks, and confidently commit to deadlines.

Portfolio highlights

• Donna — Meet Donna, the AI assistant built for field sales teams. Save time, cut admin, and close more deals with less effort.
• Netsec — Professional cybersecurity and managed IT services to protect your business 24/7.
• Electric Plant Company — We are a plant intelligence company transforming plant care today and accelerating the techno-biophillic future of tomorrow.

Portfolio highlights

• MobStac — Developer of a cloud-based mobile marketing platform designed to connect the digital and physical worlds through the use of innovative technology. The company's platform is based on the principals of proximity marketing and engage customers in a personalized, context-aware way that leverages indoor location and proximity, enabling businessesand brands to leverage BLE beacon technology to deliver context-rich experiences to their end users.
• Krux — Use Salesforce's data management platform (DMP) to unify your data and strengthen customer relationships across every touchpoint.
• Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.

Portfolio highlights

• Rebill — Rebill.com is the payments and subscriptions platform specifically designed for digital businesses and global companies scaling in Latin America.With our platform and API, companies can integrate over 100 local payment methods from the region, including cards, bank transfers, cash, and even wallets. In addition, they always receive the best humansupport with fair pricing and utmost transparency, enabling them to scale across the region 10 times faster.We are backed and have received investment from some of the world's leading funds such as Tiger Global Management, Soma Capital, SV Angel, Y Combinator, as well as incredible angel investors like Guillermo Rauch (Vercel), Arash Ferdowsi (Dropbox), among others.
• FirstWork — Applied AI for frontline enterprises. Forward-deployed AI agents that automate workforce operations inside your existing systems.
• Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.

Portfolio highlights

• GenHealth.ai — GenHealth.ai provides healthcare solutions using generative AI trained on encoded medical events. Its product is a generative healthcare AI publicly available. It includes a foundation transformer model (new neural networks with excellent memory), an API, and user applications that can generate and predict future sequences of health events usinghistorical events. Together they can be used to build a large variety of customized applications.
• Dynamic Creatures — Dynamic Creatures creates responsive character robots for the entertainment and service sectors.
• Nebex — NEBEX is a successful middle market investment intermediary. NEBEX, has completed over 100 transactions throughout the United States. New England Business Exchange concentrates on representing sellers whose business appeals to large corporate buyers or private equity groups.

Portfolio highlights

• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• North.cloud — Automate your enterprise-grade cloud finance with zero effort. Our AI reduces your cloud bill by 50% without any risk, contracts, or technical work.
• Uvi — Uvi provides infrastructure that serves as a context and reasoning layer for enterprise AI agents. The platform resolves internal corporate vocabulary, tracks dependencies, and reconstructs the decision-making intent scattered across disparate systems like Jira, GitHub, and Slack. By unifying data fragments into an integrated knowledge network, it enables AI tools to process query objectives accurately while enforcing existing user access permissions at the retrieval stage.

Portfolio highlights

• Scuba — Scuba is an AI-powered shared context engine and productivity platform built to serve as a unified "shared memory" for teams and their digital AI agents.
• Firefly — Firefly provides an integrated safety platform that helps organizations manage daily operations and emergency response through software and hardware solutions. Its Ember Safety Platform combines cloud-based tools like AI-driven mapping, mass communications, and emergency service integration with physical devices such as panic buttons, gunshot detection, and readiness systems. The platform supports tailored safety workflows that streamline procedures and improve situational awareness across different environments. Firefly’s onboarding process includes generating 3D site maps and connecting existing infrastructure to enable protocol customization and real-time alerting. The company’s offerings aim to unify safety functions in a single system that assists teams in coordinating actions from routine tasks to urgent incidents.
• Funnel — Our revolutionary CRM property management software saves both time and money for agents and owners while making leasing more efficient.

Portfolio highlights

• Actively — Actively is custom-built AI for GTM teams.
• Serval — Serval is the AI-native ESM that automates employee requests, onboarding/offboarding, just-in-time access, and more.
• Mach9 — Mach9 is building the operating system for cities. We're monitoring surface and underground infrastructure to predict and prevent infrastructure failures.

Portfolio highlights

• Uhana — Modernize your RAN to be open and programmable, built with a rich ecosystem of partners. Learn about VMware RAN Intelligent Controller (RIC).
• erytech — ERYtech Pharma, set up in Lyon (France) in 2004, specializes in the encapsulation of therapeutic molecules and enzymes in red blood cells. It has achieved a major breakthrough in the fields of cancer and enzyme therapy by significantly increasing the therapeutic index of the encapsulated molecule or enzyme.
• Sportsrocket — Sportsrocket is a New York-based company working to give sports fans access to live games and events, highlights, and shows. The company works with leading leagues, publishers, and rights-holders, including Major League Soccer, the PGA Tour, Scout Media, and AS Roma, to create and power customized OTT platforms. Incubated by Bedrocket Media Ventures, Sportsrocket's innovative approach is based on a proprietary sports media operating system, that offers an integrated solution for the production, distribution, management, and monetization of sports media across all platforms.

Portfolio highlights

• Halla — Halla Intelligence is a digital solution that leverages over 100 billion shopper and product data points to recommend and promote what grocery items.
• Verdex Technologies — Verdex Technologies is an advanced materials platform technology that uses nanofibers to disrupt industries. Verdex doesn't just compete, it innovates and disrupts.
• Samphire Neuroscience — Samphire Neuroscience builds clinically validated neurotechnology to support women across their lives. Our wearable devices, Nettle™ and Lutea™, are built on the same underlying brain-stimulation technology, targeting neural pathways involved in pain, mood, stress, and sleep regulation. - Lutea™ is available globally as a wellness device. Itstimulates the same regions of the brain to support stress regulation, sleep, and recovery - key drivers of readiness and long-term performance - allowing athletes and teams to move beyond wellbeing education alone to practical, evidence-based intervention. - Nettle™ is a CE-marked (EU and UK regulated), drug- and hormone-free device that has been clinically shown to improve pain, mood, functionality, and the ability to train during the menstrual cycle, with measurable benefits after one month of use - supporting athletes to maintain training intensity and movement quality during their period. - The Samphire App is the platform controlling all Samphire hardware products with the use of CycleSync™ AI technology: the only one of its kind to support personalized neurotechnology use for women.

Portfolio highlights

• Augmeta.ai — AI Operators work 24/7 across your systems to stop revenue leaks and chase upside, acting within your goals and guardrails or alongside your team.
• BoobyBiome — BoobyBiome harnesses breast milk microbiome science to develop products to improve infant health
• Lighter Living — Marjolein Brugman is responsible for bringing the Pilates Method to the mainstream. An accident 10 years ago taught her about the profound benefits of Pilates as she rehabilitated her own hips and watched her life change. Marjolein began her Pilates training in New Mexico, in 1997 and has continued to study and learn about Pilates all over theworld. Her dedication to the understanding of postural health and whole body fitness and her vast teacher training has made her the perfect spokesperson for the Pilates Method. She was instrumental in producing the first educational advertisement about Pilates in 1995 and has spent the last 9 years demonstrating and educating communities, worldwide via workshops and television. Together with Stamina Products, she has developed affordable Pilates equipment with training videos for home use. The recent launch of her Basic AeroPilates® Reformer training through SCW has been received with great enthusiasm by the fitness industry.

Portfolio highlights

• Seeo — Daftar akun togel resmi bisa melalui via dana, ovo, gopay, linkaja kami juga menyediakan berbagai link togel terpercaya seperti bo togel hadiah 2d 200rb, bandar togel hadiah 4d 10 juta terpercaya, situs togel resmi dan terpercaya, agen togel terpercaya, daftar bandar togel terbesar dan terpercaya, bandar togel terbesar, situs togel prize 123, bo togel bolak balik dibayar dan banyak lainnya yang kami sediakan untuk pencinta link togel resmi di Indonesia.
• Anrok — Anrok automates sales tax compliance across your financial stack, so you can grow your SaaS business in any market.
• LanzaTech — LanzaTech offers a technology platform that transforms industrial waste gases such as carbon monoxide and carbon dioxide into valuable chemical intermediates and fuels through microbial gas fermentation. The company’s process captures emissions from heavy-industry sources and uses specialized microbes to convert those gases into ethanol, which is then refined into materials such as monoethylene glycol for packaging, solvents, proteins, and sustainable aviation fuels. LanzaTech integrates its bioconversion system with industrial emitters, enabling the reuse of carbon streams that would otherwise be released into the atmosphere, and supplies downstream manufacturers in sectors including packaging, textiles, and aviation with fossil-alternative feedstocks.

Portfolio highlights

• FFID — FFID develops AI chatbot platform automating customer communication, lead generation, and marketing workflows.
• SprayX — Company specialized in interactive process control to evaluate and guarantee the quality of agricultural spraying with excellence. Empowers, leads and monitors applicators in Application Technology tasks.
• Sandwiche — Sandwiche creates customizable link in bio pages enabling social media monetization and affiliate marketing management.

Portfolio highlights

• Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
• ngmoco — ngmoco ("Next Generation MObile COmpany") is creating and producing games for the iPhone. CEO Neil Young is a former executive from Electronic Arts, where he oversaw the development of several hit titles. Another EA vet and partner at Kleiner Perkins, Bing Gordon, sits on the board. Kleiner is an investor through its iFund.
• SolveAI —

Portfolio highlights

• Stromedix — sohibslot merupakan situs slot gacor 4d dengan server thailand yang terkenal gampang menang di tahun 2026, deposit withdraw cepat, akses cepat dan stabil.
• Valence — Work better. Together.
• Simply Measured — Reimagine how social media can grow your business with Sprout Social. See our social media management tools in action. Start your own free trial today.

Portfolio highlights

• Axiom — Axiom is an AI technology company that builds next-generation AI mathematicians.
• Sapphire Digital — UFABRO situs judi bola dengan keamanan maksimal, enkripsi SSL, transaksi stabil, lisensi terverifikasi, dan layanan yang transparan. Mudah digunakan dan sangat andal.
• Rocker — Rocker develops a secure, cloud-deployed AI assistant designed to integrate into corporate environments to automate tasks, manage project workflows, and enhance internal collaboration across teams.

Portfolio highlights

• SaveUp — SaveUp is the first free rewards program for saving money and reducing debt. Users earn SaveUp credits for every dollar saved or debt reduced and can use these credits to play for prizes ranging from travel, cars to even a $2M jackpot. While using SaveUp users are provided financial education, suggestions to improve their financial circumstancesand better financial services. SaveUp can be used with 18,000 financial institutions in the US including rewards for savings accounts, 401k, IRA, or reducing debts like credit cards, car loans, student loans and mortgages.
• Smarterer — Individuals and Fortune 500 companies use Smarterer to help close the gap between the skills they have and the skills they need. Their dynamic assessment engine leverages the freshest crowdsourced tests around, to rapidly pinpoint skill level with a credible score. In November 2014, Pluralsight, the global leader in online learning for serioussoftware developers, IT specialists and creative technologists, acquired Smarterer. As the world's largest curated e-learning library for professionals, the company offers instant access to more than 3,500 courses authored by top experts. Smarterer will continue to power crowdsourced assessments for freelancer marketplaces, e-learning providers and enterprise companies anywhere people need to prove their skills to connect with professional opportunities. The Smarterer community has answered over 56 million during 1.7 million test sessions, across hundreds of tests.
• Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.

Portfolio highlights

• HUNTY — HUNTY is a platform that help people find jobs by connecting them with world class mentors who prepare them for the job search process. And people only pay when they get hired.
• Goodweek — The AI management platform that gives partners and businesses one secure place for every AI model.
• Clarity Care AI — Clarity Care AI develops healthcare artificial intelligence software that supports care delivery and operations. The platform assists clinicians and care teams with documentation, task management, and communication around patient needs. Features include note drafting, summarization of patient information, and notifications that flag items requiring follow-up. Integrations connect to existing tools to streamline handoffs and keep records consistent across teams. Analytics highlight trends in patient status and operational workload to inform daily decisions. Implementation services, training resources, and ongoing product support help healthcare organizations adopt and use the software.

Portfolio highlights

• SuperMe — SuperMe brings the experience of people who've done it into your work. Think it through with them, and let your own work speak for itself.
• Snorkel AI — Snorkel AI builds specialized training data, benchmarks, and evaluation environments that help frontier models and agents perform in high-stakes domains.
• Lightfield — Lightfield is an AI-native CRM for companies to capture, analyze, and understand everything about their customers.

Portfolio highlights

• Snag — Snag operates an AI-powered housing marketplace and rental discovery platform.
• Steven.com — The operating system for the creator economy. Connecting creators to resources, platforms, community and technology where trust shifts to individuals.
• Otter Health — Otter Health is a healthcare firm that focused on AI-powered utilization management and clinical intelligence for payers and providers.

Portfolio highlights

• Polars — Polars is the fastest open-source DataFrame library for Python and Rust, and the framework that takes the same query from a laptop to the cloud.
• MedeAnalytics — Enhance health outcomes and reduce costs through effective healthcare data analytics that provide actionable insights and clarity.
• ZeroTurnaround — ZeroTurnaround is a small, fast-growing start-up based in Tartu, Estonia. The company is the creator of JRebel, an award-winning Java development productivity tool.JRebel a JVM plugin that eliminates the build and redeploy phases of the J2E development cycle.Based on a survey completed in 2010 from over 1100 J2E developers, it was discoveredthat between 10 - 23% of each development hour is spent on turnaround. Turnaround is the time it takes for the changes in code to propagate to the running application. It includes build time, deploy time and initialization time.JRebel monitors Java classes and reloads the changes in real-time without restarting your application or losing any state. It does not require a debug mode and, unlike built-in JVM HotSwap, supports class schema changes like adding methods or fields.

Portfolio highlights

• Aries — an open platform for traders, investors, and developers
• Modal Labs — Modal develops machine learning software to help run code in the cloud. The software enables users to run or deploy machine learning models, massively parallel compute jobs, task queues, web apps, and more. It also writes the code to launch hundreds of custom containers and runs scripts in the cloud faster than on the local machine.
• Flapping Airplanes — Flapping Airplanes is an artificial intelligence research lab that focuses on advancing foundational AI technologies with an emphasis on data-efficient model development and fundamental research into next-generation learning approaches. The organization’s work centers on exploring alternative training paradigms that reduce dependency on massivedatasets and compute scale, aiming to enable systems that learn with efficiency more akin to human cognition rather than brute-force training methods. Its team includes researchers and technical experts pursuing long-horizon scientific challenges in AI architecture, training mechanisms, and algorithmic innovation. Flapping Airplanes engages with investors and collaborators to support its research agenda, backing efforts that expand the theoretical and practical frontiers of artificial intelligence without immediate commercial product constraints. While the lab operates primarily as a research-first initiative, its findings are intended to inform future applications in areas such as enterprise AI, robotics, scientific discovery, and decision systems. The company’s strategy reflects a shift away from traditional scale-focused AI development toward exploring deep, principled advances in learning efficiency and model capabilities.

Portfolio highlights

• Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
• Cyphort — Cyphort has developed Next Generation Distributed Software Platform to provide the broadest enterprise visibility and accurate detection of advanced threats & evasion techniques, and zero-day attacks by utilizing behavioral analytics, machine learning, and Long-Data Security-Analytics.Cyphort's innovative approach detects the mostadvanced threats through a highly accurate platform combined with validation and prioritization of threats in context of the organizations eco-system. Through this process Cyphort produces highly customized Actionable Intelligence to users.The Cyphort Distributed Platform has been build with flexibility allowing for seamless integration and detection not only at the edge and network layers but also in virtual infrastructures, cloud environments, and mobile platforms.
• Fulcrum — One AI platform for the entire account lifecycle, from prospecting to renewal, built into the systems your team already uses.

Portfolio highlights

• PanGenetics — PanGenetics B.V. develops monoclonal antibodies for the treatment of immune mediated diseases.PanGenetics is a clinical development company that specializes in taking antibodies from the late research stage through to clinical proof of concept. The company is based in Utrecht, the Netherlands with an office in Cambridge, UK. PanGenetics employsa lean business model with manufacturing and clinical development activities outsourced to specialist providers. Apart from PG110, the other clinical program of PanGenetics is PG102, a CD40 antagonist for treatment of autoimmune diseases which is currently being evaluated in a clinical study in psoriatic arthritis patients
• Acutus Medical — Acutus Medical develops medical technologies to treat complex cardiac arrhythmia. The company's platform displays the heart’s true activation pattern, turning the chaos of a complex arrhythmia into a clear vision for electrophysiologists.Acutus Medical is a privately funded company founded in 2011 and based in Carlsbad, California. Itsproducts are co-developed in the U.S. and Europe with an exceptional team of medical scientists, biomedical engineers, and other professionals.It was founded in 2011 and headquartered in Carlsbad, California.
• Milestone Systems — See and know more with video technology. Milestone offers award-winning XProtect video management software, Arcules VSaaS, and BriefCam analytics.

Portfolio highlights

• Lumaril — Lumaril is a software company that develops an artificial intelligence platform for optimizing physical production operations. The company connects its platform to existing industrial control systems and uses operational data, audio and visual sensors, artificial intelligence, and machine learning to model facility performance in real time. Its platform determines operational adjustments and can autonomously modify set points, control logic, and coordination to improve production throughput and yield. Lumaril serves industrial facilities in manufacturing, chemicals, biologics, and oil and gas. The company applies AI-driven automation to existing industrial infrastructure without requiring replacement of established control systems. Its technology is designed to support continuous optimization of complex production environments.
• Arda — Arda is an AI manufacturing software startup founded by Bob McGrew.
• Sooth Labs —

Portfolio highlights

• Quantcast — We are taking an entirely new approach to advertising on the open internet.
• Coherence Neuro — Opto Biosystems specializes in the development of innovative healthcare technologies that bridge the gap between cancer neuroscience and bioelectronics. The company focuses on creating smaller, softer, and wireless biological interfaces designed to offer a new treatment modality. By leveraging advancements in neural engineering and bioelectronics,Opto Biosystems is dedicated to building new tools that interface with the body, aiming to improve patient outcomes in the healthcare sector. Their work includes exploring the stability of thin-film electrodes for neuromodulation, highlighting their commitment to advancing medical technology.
• Watchtower Labs — Watchtower Labs is an AI-first team with a single mission: to solve the most difficult technical obstacles in vital simulations and defense.

Portfolio highlights

• Horizon3.ai — Horizon3.ai's mission is to help you find and fix your attack vectors before criminals exploit them. NodeZero, our automated penetration testing solution, enables organizations to continuously assess the security posture of their enterprise, including external, identity, on-prem, IoT, and cloud attack surfaces. Like APTs, ransomware, andother threat actors, our algorithms discover and fingerprint your attack surface, identifying the ways exploitable vulnerabilities, misconfigurations, harvested credentials, and dangerous product defaults can be chained together to facilitate a compromise. NodeZero is a true self-service SaaS offering that is safe to run in production and requires no persistent or credentialed agents. You will see your enterprise through the eyes of the attacker, identify your ineffective security controls, and ensure your limited resources are spent fixing problems that can actually be exploited. Founded in 2019 by industry, US Special Operations, and US National Security veterans, Horizon3.ai is headquartered in San Francisco, CA, and made in the USA.
• Arceus Legal — Redefining the future of law for the companies inventing the next decade.
• ASI — Airspace Intelligence is a software-first aerospace company that helps the world's most complex air operations succeed.

Portfolio highlights

• Nix, Inc. — Wearable single-use hydration sensor for athletes, soldiers, and laborers that measures hydration levels and informs when, what, and how much to drink.
• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• Snapp — Snapp Stats is an AI sports analyst for coaching staffs: scout opponents, evaluate players and build reports from your film notes and data. From $100/month.

Portfolio highlights

• Birdstop — Fully automated aerial imaging on your field assets through AI powered drones.
• Hyperpublic — Hyperpublic is an open database of people, places, and things tied to a specific location. Anyone can add objects to the database and developers will be able to build applications on top of the data.
• ShareWillow — ShareWillow is a SAAS company that offers a profit sharing software for companies to manage profit sharing plans.

Portfolio highlights

• Scape — Scape is an AI email client that proactively drafts replies and surfaces what matters. Built for professionals who live in their inbox.
• Numeral — We fully manage the headaches of sales tax so you can get back to real work. Get started for free today!
• Neuron Industries — Neuron Industries develops AI-native industrial controllers to replace traditional PLCs, enabling deterministic factory automation via plain English. Neuron Industries was founded in 2026 by Dennis Ren and Kenneth Rhee.

Portfolio highlights

• Presonance — Presonance provides brain-based creative testing for agencies and research partners. Its platform simulates audience responses to videos, images, and scripts to assess how creative content may influence viewer behavior. Users can analyze audience responses moment by moment and use the results to evaluate and refine campaigns before launch. Presonance also provides sample analyses and research-backed insights for creative testing.
• Phinity Labs — Phinity Labs builds AI systems designed to fully automate the entire silicon microchip engineering process, spanning from original architectural concepts to final manufacturing preparation.
• Hertha Metals — At Hertha Metals, we are developing advanced steel solutions to accelerate the growth and global competitiveness of the U.S. steel industry.

Portfolio highlights

• PodcastAI — Turn your recording into show notes, clips, and a published episode. Create Ad Reads, manage campaigns, and distribute your podcast in one place.
• Snag — Snag operates an AI-powered housing marketplace and rental discovery platform.
• Rosie Match — Rosie provides flexible childcare & household help to busy families. As a member, Rosie will connect you with a trusted Pro for your adhoc & weekly needs handling all scheduling, coordination and payments.

Portfolio highlights

• Glyde — Glyde is an innovative peer-to-peer e-commerce marketplace that makes it simple to buy and sell new and used goods. Glyde’s products include Apple and Android phones, tablets, laptops, iPods, and video games.Glyde’s e-commerce engine absorbs complexity, making the user experience faster and easier than other marketplaces. Buyers enjoy thegreat deals of a peer-to-peer marketplace combined with the service, convenience, and safety of a retail store. Sellers enjoy a streamlined experience that connects them with eager and qualified buyers. It takes seconds to list an item for sale, and shipping is effortless with Glyde’s pre-addressed, pre-stamped mailers.Created by the founder of eBay Motors, Glyde is brought to you by veterans from industry-defining companies such as eBay, Google, and Wal-Mart. Glyde is venture backed with an office in Menlo Park, CA.
• SendCutSend — Online sheet metal fabrication service. Get custom parts delivered in just a few days. Upload STEP or DXF files for instant pricing!
• Flapping Airplanes — Flapping Airplanes is an artificial intelligence research lab that focuses on advancing foundational AI technologies with an emphasis on data-efficient model development and fundamental research into next-generation learning approaches. The organization’s work centers on exploring alternative training paradigms that reduce dependency on massivedatasets and compute scale, aiming to enable systems that learn with efficiency more akin to human cognition rather than brute-force training methods. Its team includes researchers and technical experts pursuing long-horizon scientific challenges in AI architecture, training mechanisms, and algorithmic innovation. Flapping Airplanes engages with investors and collaborators to support its research agenda, backing efforts that expand the theoretical and practical frontiers of artificial intelligence without immediate commercial product constraints. While the lab operates primarily as a research-first initiative, its findings are intended to inform future applications in areas such as enterprise AI, robotics, scientific discovery, and decision systems. The company’s strategy reflects a shift away from traditional scale-focused AI development toward exploring deep, principled advances in learning efficiency and model capabilities.

Portfolio highlights

• Bacca.ai — Bacca is an AI engineer that takes full responsibility for your software after you ship it.
• Evos — Evos is an AI-powered operations platform designed to transform how companies run their internal processes by turning manual workflows into autonomous, intelligence-driven systems. The platform is positioned for industries like logistics, manufacturing, energy, real estate, telecom, and retail, where operations teams are often overloaded with repetitive, multi-system tasks. A key focus is eliminating inefficiencies such as exception handling, coordination across multiple platforms, and manual data processing.
• Phinity Labs — Phinity Labs builds AI systems designed to fully automate the entire silicon microchip engineering process, spanning from original architectural concepts to final manufacturing preparation.

Portfolio highlights

• Dren Bio — Dren Bio is a biotechnology company with a portfolio of attractive projects focused on powerful protein engineering technologies for the depletion of cells, protein aggregates, and other disease-causing agents. It is a holding company business model aimed at creating value with multiple projects as stand-alone assets.
• Fragment — Fragment automates complex, exception-heavy procurement workflows with AI agents.
• Hello Patient — Healthcare AI that gets your team off the phone & in front of patients

Portfolio highlights

• Praktiki — Praktiki is the AI platform for medical education: expert-led, case-based 5-minute modules HCPs love, built in hours and measured for behaviour change.
• ReportsAI — ReportsAI is an impact operating system that automates data collection and reporting for NGOs and industry to ensure audit-ready compliance.
• Plouton AI —

Portfolio highlights

• Sava — Sava offers an AI-powered platform that automates trust setup, funding, and administration.
• Pathfinder AI — Pathfinder AI provides psychometric assessments, career counseling, and admission guidance to help students explore and plan their futures.
• Collective — Collective offers financial solutions designed for self-employed business owners - company formation, tax, accounting & bookkeeping.

Portfolio highlights

• AdReady — Digital Remedy is an unparalleled digital media company, providing innovative solutions in OTT, CTV, and performance TV advertising. Discover our tools today.
• Axiom — Axiom is an AI technology company that builds next-generation AI mathematicians.
• Mercent — Rithum is the connected commerce operations platform helping brands and retailers list, fulfill, and optimize products across every channel.

Portfolio highlights

• Adimab — Premier Human Antibody Discovery and Optimization
• Reflex — The open-source framework to build and deploy web apps using Python.
• Cajal Neuroscience — Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease.

Portfolio highlights

• FluxCap — FluxCap is an AI-powered legal technology company that helps lawyers handle complex litigation and build stronger legal cases. It combines advanced technology with legal expertise to support case strategy, evidence analysis, and legal reasoning. Its mission is to make justice more accessible by helping legal teams take on more high-impact cases.
• Clay — Clay's spreadsheet helps you find, enrich and act on people and company data from any source - without a line of code. Get started for free, today.
• Smack Technologies — We're not defense tech tourists. Meet the warfighters, scientists, and engineers building the first Frontier AI Lab for National Security.

Portfolio highlights

• Legato Audio — Legato Hearing develops stylish glasses with built-in hearing technology, offering a discreet alternative to traditional hearing aids.
• Cast Insights — Cast Insights is an AI-powered platform that turns global spoken content—TV, radio, podcasts, livestreams—into structured, searchable real-time intelligence for investors, policy teams, strategists, and newsrooms.
• General Compute — General Compute provides an ASIC-based cloud inference platform focused on running AI inference workloads. The company offers an OpenAI-compatible API that allows users to access hosted large language models and switch from existing GPU-based providers by changing the base URL and API key. It supports deploying both its own supported models andcustomer-supplied models on its infrastructure, emphasizing high token throughput and low time to first token. General Compute also offers dedicated custom deployments with service-level agreements, custom scaling, and guaranteed capacity for production workloads. Its infrastructure targets use cases such as AI agents, coding assistants, and real-time voice applications that require low-latency, high-throughput inference.

Portfolio highlights

• Meadow AI — Meadow AI is developing the retail and restaurant industries' operational brains. Our multimodal AI platform transforms POS, audio, and camera data into insights and actions in real time.
• Allswell — Allswell is a queer-founded mental health platform dedicated to making affirming, accessible care available to the LGBTQ+ community, covered by Medicaid & major insurance.
• TerraBlaster — TerraBlaster is a cutting-edge agricultural technology firm focused on transforming sustainable agriculture through enhanced automation and precise technologies.

Portfolio highlights

• ChampionHQ — ChampionHQ operates as a customer marketing platform to activate your customers and fans to create post-sale marketing programs.
• Yourco — Yourco helps organizations reach frontline employees, manage workforce interactions, and automate routine work with AI. Through two-way SMS, Yourco makes frontline communication and workflows easier to manage while giving organizations greater visibility across their workforce.
• Tab Commerce — Tab Commerce helps restaurants of all sizes consolidate, analyze, and better manage every single expense they have.