# Top 50 Manufacturing Startup Investors in United States in June 2026

## SOSV
- Type: VC Fund
- Location: Princeton, New Jersey, United States
- Relevant deals: 61
- Stages: Seed, Convertible Note, Pre-Seed
- Focus: Biotechnology, Health Care, Software

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates.
HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

## Alumni Ventures
- Type: VC Fund
- Location: Manchester, New Hampshire, United States
- Relevant deals: 53
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Information Technology

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

## Lux Capital
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 36
- Stages: Series A, Seed, Series B
- Focus: Software, Artificial Intelligence, Health Care

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

## Khosla Ventures
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 31
- Stages: Series A, Series B, Seed
- Focus: Software, Artificial Intelligence, Health Care

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

## Founders Fund
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 29
- Stages: Series A, Seed, Series B
- Focus: Software, Health Care, Information Technology

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

## Toyota Ventures
- Type: VC Fund
- Location: Los Altos, California, United States
- Relevant deals: 27
- Stages: Series A, Seed, Series B
- Focus: Artificial Intelligence, Software, Robotics

Toyota Ventures is a San Francisco Bay Area-based venture capital firm that invests in early-stage startups from around the world. Founded in July 2017, its mission is to discover what’s next for Toyota by helping startups bring disruptive technologies and business models to market quickly. With more than $800 million in assets under management,the firm’s funds include the Toyota Ventures Frontier Fund focused on artificial intelligence, cloud computing, autonomy, mobility, robotics, financial technologies, materials, and energy; and the Toyota Ventures Climate Fund focused on innovative solutions for carbon neutrality.

## Innova Memphis
- Type: VC Fund
- Location: Memphis, Tennessee, United States
- Relevant deals: 26
- Stages: Seed, Pre-Seed
- Focus: Health Care, Medical, Medical Device

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

## Eclipse
- Type: VC Fund
- Location: Palo Alto, California, United States
- Relevant deals: 24
- Stages: Series A, Series B, Seed
- Focus: Software, Robotics, Artificial Intelligence

Palo Alto based Eclipse Ventures partners with entrepreneurs boldly transforming the essential industries that define and propel economies. Learn more.

## Clean Energy Ventures
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 24
- Stages: Seed, Series A
- Focus: Manufacturing, Energy, Renewable Energy

Clean Energy Ventures invests in scalable early-stage climate tech startups and clean energy technologies addressing global climate change.

## Gaingels
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 24
- Stages: Seed, Series A, Series B
- Focus: Software, Health Care, Artificial Intelligence

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

## Breakthrough Energy Ventures
- Type: VC Fund
- Location: Paris, Ile-de-France, France
- Relevant deals: 23
- Stages: Series A, Series B
- Focus: Energy, Renewable Energy, Manufacturing

Focused on developing and deploying the critical climate solutions our world needs to reach net-zero emissions by 2050.

## Fifty Years
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 22
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Artificial Intelligence

WE BACK HEROES   using technology to solve the world's biggest problems

## Houston Angel Network
- Type: VC Fund
- Location: Houston, Texas, United States
- Relevant deals: 21
- Stages: Seed, Series A
- Focus: Health Care, Software, Medical

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

## Andreessen Horowitz
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 21
- Stages: Series A, Seed, Series B
- Focus: Software, Information Technology, Artificial Intelligence

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

## Collaborative Fund
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 21
- Stages: Seed, Series A
- Focus: Software, Food and Beverage, Health Care

Collaborative Fund is a leading source of capital for entrepreneurs pushing the world forward.

## Intel Capital
- Type: VC Fund
- Location: Santa Clara, California, United States
- Relevant deals: 20
- Stages: Series B, Series A, Series C
- Focus: Software, Information Technology, Enterprise Software

Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies.

## Flybridge
- Type: VC Fund
- Location: Boston, Massachusetts, United States
- Relevant deals: 20
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Information Technology

New York and Boston Based Early-Stage Venture Capital Firm Backing Seed Stage AI Companies. Focused on AI Enablement, Developer Platforms, Agentic Business Applications, and Native AI for Human Ingenuity

## Right Side Capital Management
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 20
- Stages: Seed, Pre-Seed, Convertible Note
- Focus: Software, SaaS, Health Care

Systematic Pre-Seed Startup Capital

## Climate Capital
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 20
- Stages: Seed, Pre-Seed, Series A
- Focus: Energy, Manufacturing, Renewable Energy

Diversified investments in the most promising early stage climate startups backed by top tier VCs.

## Asymmetry Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 19
- Stages: Seed, Series A, Pre-Seed
- Focus: Software, Health Care, Biotechnology

Asymmetry Ventures invests in scalable early-stage companies with exceptional defensibility.

## Maine Angels
- Type: VC Fund
- Location: Portland, Maine, United States
- Relevant deals: 18
- Stages: Seed, Series A
- Focus: Health Care, Software, Biotechnology

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

## Mark Cuban
- Type: Angel
- Location: Dallas, Texas, United States
- Relevant deals: 18
- Stages: Seed, Series A
- Focus: Software, Artificial Intelligence, Blockchain

Mark Cuban is the founder of Fireside, Chairman and Founding Partner of AXS TV, and the Owner of Dallas Mavericks. He previously worked at Broadcast.com as a Co-Founder. Mark Cuban attended the Indiana University Bloomington.

## Jackson Moses
- Type: Angel
- Location: Palo Alto, California, United States
- Relevant deals: 18
- Stages: Pre-Seed, Seed, Series A
- Focus: Aerospace, National Security, Military

Jackson Moses is the Founder and Managing Partner of Silent Ventures. He previously worked at ThinkOrbital as an Advisor. Jackson attended the University of California, Berkeley, where he took a Bachelor of Arts in Economics with a focus on Monetary Policy and a Bachelor of Arts in Political Science with a focus on Game Theory.

## New Enterprise Associates
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 18
- Stages: Series A, Series B, Series C
- Focus: Software, Health Care, Biotechnology

Foundational partners to ambitious founders at every stage of company-building.

## Advantage Capital
- Type: VC Fund
- Location: New Orleans, Louisiana, United States
- Relevant deals: 18
- Stages: Debt Financing, Series A
- Focus: Manufacturing, Software, Health Care

Advantage Capital has invested over $3.8 billion in more than 800 portfolio companies and projects nationwide since 1992. The firm specializes in growth equity, lending, and mezzanine debt capital investments spanning three distinct but complementary themes, driving local economic development and lasting impact in underserved communities.____________________Growing Small Business // 800+ PORTFOLIO COMPANIES // 34 STATES // 66,000+ JOBS SUPPORTED //
Small businesses and the entrepreneurs who power them are fundamental to the U.S. economy, driving inclusive economic expansion that allows people and communities to thrive.
Advantage Capital offers debt and equity investment opportunities and can provide senior, unitranche and subordinated debt, as well as minority equity financing. The firm invests in companies from a diverse array of industry sectors, including manufacturing, technology and business services, among others. It seeks to make an initial investment between $500K and $10M in companies with $1M+ EBITDA.Financing Affordable Homes // 89 PROJECTS SINCE 2015 // 8,000+ FAMILIES & SENIORS HOUSED // 7 STATES //
Creating stronger communities goes beyond business investment and jobs. Financing housing in these same communities creates even more positive and lasting impacts.Expanding Renewable Energy Solutions // $130M IN CAPITAL DEPLOYED // 65 PROJECTS // 20,000+ HOMES POWERED //
Increased access to renewable energy supports local green jobs and economic development while building the framework for tomorrow's carbon-free America.
____________________Geographic Focus: Advantage Capital is committed to impact nationwide, with current emphasis in the following states: Alabama, Arkansas, Connecticut, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Mexico, Ohio, Pennsylvania, Tennessee, Texas, Utah, Virginia, West Virginia____________________Advantage Capital is headquartered in New Orleans, Louisiana and has offices in the following locations: St. Louis, MO; New York, NY; Austin, TX; Hanover, NH; Washington, D.C.; Napa, CA; Nevada.

## BoxGroup
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 18
- Stages: Seed, Series A, Series B
- Focus: Software, Health Care, Artificial Intelligence

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

## Congruent Ventures
- Type: VC Fund
- Location: Oakland, California, United States
- Relevant deals: 17
- Stages: Seed, Series A, Series B
- Focus: Software, Energy, Robotics

Congruent Ventures is a venture capital firm that seeks to invest in Mobility and Urbanization, Energy Transition, Food and Agriculture, and Sustainable Production & Consumption sectors. We look for technology companies that will positively impact our energy and resource consumption. If we see an opportunity to partner with a like-minded teamfocused on scale across hardware, software, or services, we’re interested.

## Liquid 2 Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 17
- Stages: Seed, Series A, Pre-Seed
- Focus: Software, Artificial Intelligence, Information Technology

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

## Draper Associates
- Type: VC Fund
- Location: San Mateo, California, United States
- Relevant deals: 17
- Stages: Seed, Series A, Series B
- Focus: Software, FinTech, Information Technology

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

## Cantos
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 17
- Stages: Seed, Series A, Pre-Seed
- Focus: Software, Biotechnology, Health Care

Investing in the Near Frontier

## Creative Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 16
- Stages: Seed, Series A
- Focus: Software, Health Care, Biotechnology

Creative Ventures is a deep tech venture firm investing in early-stage companies solving humanity’s most critical crises. Led by a team of world-class experts, our deep tech acumen is informed by rigorous research, unmatched market understanding, and the dedication to lead our companies to success.Today’s problems can’t be solved by yesterday’ssolutions. Let’s get Creative.

## MB Venture Partners
- Type: VC Fund
- Location: Memphis, Tennessee, United States
- Relevant deals: 16
- Stages: Seed, Series B, Series C
- Focus: Health Care, Medical, Medical Device

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

## Sequoia Capital
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 16
- Stages: Series A, Series B, Series C
- Focus: Software, Information Technology, Artificial Intelligence

We help the daring build We help the daring build legendary companies from idea to IPO and beyond. companies.

## The Engine
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 16
- Stages: Seed, Series A, Series B
- Focus: Biotechnology, Health Care, Manufacturing

A home for Tough Tech founders.

## Kleiner Perkins
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 16
- Stages: Series B, Series A, Series C
- Focus: Software, Health Care, Information Technology

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

## General Catalyst
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 15
- Stages: Series A, Seed, Series B
- Focus: Software, Artificial Intelligence, Health Care

Investing in powerful, positive change that endures

## Prelude Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 15
- Stages: Series A, Series B, Series C
- Focus: Software, Energy, Renewable Energy

Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. For us, climate is everything.

## Good Growth Capital
- Type: VC Fund
- Location: Charleston, South Carolina, United States
- Relevant deals: 15
- Stages: Seed, Series A, Convertible Note
- Focus: Health Care, Biotechnology, Software

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

## Root Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 15
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Machine Learning

Root Ventures is a seed-stage venture capital firm that invests in technical teams working on deep tech. The firm specializes in the fields of financial services, venture capital, and investments.

It was founded in 2013 and headquartered in San Francisco, California.

## Schematic Ventures
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 15
- Stages: Seed, Pre-Seed, Series A
- Focus: Software, Logistics, Artificial Intelligence

Early-stage venture capital fund focused on investments in technology companies within the supply chain, manufacturing and digital industrial sectors

## SBXi
- Type: VC Fund
- Location: Cambridge, Massachusetts, United States
- Relevant deals: 14
- Stages: Pre-Seed, Seed
- Focus: Artificial Intelligence, Software, Information Technology

SBXi is jointly sponsored by nine firms. We offer equity funding for MIT founders who are working on a term sheet with a lead investor.

## Ben Franklin Technology Partners of Northeastern Pennsylvania
- Type: VC Fund
- Location: Bethlehem, Pennsylvania, United States
- Relevant deals: 14
- Stages: Grant, Seed, Debt Financing
- Focus: Manufacturing, Software, Health Care

Ben Franklin helps early-stage technology companies and established manufacturers translate innovation into commercial success and economic prosperity.

## Lerer Hippeau
- Type: VC Fund
- Location: New York, New York, United States
- Relevant deals: 14
- Stages: Seed, Series A, Series B
- Focus: Software, E-Commerce, Mobile

Lerer Hippeau is an early-stage venture capital fund based in New York City. As founders and operators ourselves, we see returns in relationships

## Launch NY
- Type: VC Fund
- Location: Buffalo, New York, United States
- Relevant deals: 14
- Stages: Convertible Note, Seed, Pre-Seed
- Focus: Health Care, Software, Food and Beverage

Launch NY is a U.S. Treasury-designated Community Financial Institution (CDFI) and a 501(c)(3) nonprofit venture development organization, providing pro bono mentoring and capital access to high-growth potential startups across Upstate NY. The mission is to identify, support and invest in high-growth, high-impact companies, and catalyze theentrepreneurial culture in the 27 counties comprising the western half of Upstate New York.

## Revolution’s Rise of the Rest Seed Fund
- Type: VC Fund
- Location: Washington, District of Columbia, United States
- Relevant deals: 14
- Stages: Seed, Series A
- Focus: Software, SaaS, Information Technology

Investing catalytic capital in promising seed stage companies located outside of Silicon Valley, NYC & Boston. Backed by a group of iconic entrepreneurs, executives & investors.

## Lightspeed Venture Partners
- Type: VC Fund
- Location: Menlo Park, California, United States
- Relevant deals: 14
- Stages: Series A, Series B, Seed
- Focus: Software, Information Technology, Artificial Intelligence

Lightspeed Venture Partners is a multi-stage venture capital firm focused on accelerating disruptive innovations and trends.

## Clean Energy Venture Group
- Type: VC Fund
- Location: Brookline, Massachusetts, United States
- Relevant deals: 14
- Stages: Seed, Series A
- Focus: Energy, Renewable Energy, Manufacturing

CEVG is an angel investor collective that invest in and mentors early-stage cleantech and climatetech startups across North America.

## Lockheed Martin Ventures
- Type: VC Fund
- Location: Bethesda, Maryland, United States
- Relevant deals: 13
- Stages: Series B, Series A
- Focus: Aerospace, Software, Artificial Intelligence

As a leading technology and innovation company, Lockheed Martin is committed to the next big idea.

## Propel(X)
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 13
- Stages: Seed, Series A, Series B
- Focus: Health Care, Biotechnology, Software

Propel(x) is where investors discover, evaluate and invest in technology startups and venture capital funds.

## DCVC
- Type: VC Fund
- Location: San Francisco, California, United States
- Relevant deals: 13
- Stages: Seed, Series A, Series B
- Focus: Software, Artificial Intelligence, Machine Learning

We are deep tech venture capital.

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