Top 50 Medical Device Startup Investors in United States in September 2025

Investor	Medical Device United States investments
Innova Memphis	71
SOSV	20
Portfolia	19
HealthTech Capital	19
Broadview Ventures	18
CincyTech	17
TEDCO	17
MB Venture Partners	16
North Coast Ventures	16
Oxford Finance LLC	15
Connecticut Innovations	15
Texas HALO Fund	15
Maine Angels	15
Wavemaker 360	14
Boston Harbor Angels	14
Arboretum Ventures	14
Ben Franklin Technology Partners of Southeastern Pennsylvania	13
Good Growth Capital	13
Versant Ventures	13
Khosla Ventures	13
Sand Hill Angels	12
Catalyst Health Ventures	12
Houston Angel Network	12
Wisconsin Investment Partners	12
Life Science Angels	12
Catalyst Health Ventures	12
Canaan Partners	11
Tech Coast Angels	11
U.S. Venture Partners	11
Gaingels	11
Third Rock Ventures	11
Asset Management Ventures (AMV)	11
Horizon Technology Finance	11
Kleiner Perkins	11
Rev1 Ventures	11
Shangbay Capital	10
St. Louis Arch Angels	10
Hatteras Venture Partners	10
Sante Ventures	10
Rockies Venture Club	10
The Vertical Group	10
Emergent Medical Partners	10
New York Angels	10
Three Arch Partners	10
Keiretsu Forum	10
Alumni Ventures	10
Oxford Bioscience Partners	10
DeNovo Ventures	10
Keiretsu Capital	10
Morgenthaler Ventures	10

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Funding Round
United States, Argentina, United Kingdom

Portfolio highlights

HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.
Soiltech Wireless — Soiltech Wireless is a developer of ag-tech solutions to design electronic devices for agricultural professionals. Its product provides real-time data to drive efficiency and optimize quality. It also provides actionable data without installation hassles and creates scalable monitoring solutions for farmers.The company was founded in 2019 and isheadquartered in Rupert, Idaho.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Software, Biotechnology
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and
Mercy BioAnalytics — We are making early stage cancer 100,000x easier to find using extracellular vesicles found in blood, specific to their parent cells.
Zero Point Five Therapeutics — A drug development company treating soil transmitted helminthiasis (STH) through the FDA as a single dose formulation. STH is a disease impacting poor rural communities of color with poor sewage systems.

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

Investment focus

Health Care, Medical Device, Medical
Seed, Series A, Convertible Note
United States, Canada

Portfolio highlights

xCures — An AI-assisted platform that gathers medical records from anywhere. It extracts clinical insights, resulting in significant information gain.
S2 Genomics — The Singulator Platform automates the dissociation of tissues into single cells and nuclei for genomics applications. Learn more at S2genomics.com
GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.

Broadview Ventures, Inc. (Broadview) was established in 2008 as a new program conceived by the Leducq family. Through Broadview, the trust will work to accelerate the development of promising technology in cardiovascular and neurovascular disease through targeted investment in and support of early stage technology ventures.The FoundationLeducq, based in Paris, France, is the beneficiary of a charitable trust. In order to further the Foundation Leducq's mission in cardiovascular and neurovascular disease, the trust has made funds available to Broadview to develop a program which will promote early state technology in these fields through investments, licensing agreements and consortium funding arrangements, as well as professional, management and consulting support.With this initiative the trust joins other leaders in the venture philanthropy movement in seeking creative solutions to the problem of what is commonly referred to as the 'translational gap', a significant component of which is a lack of funding at a critical moment in the development of new technology and science.

Investment focus

Health Care, Biotechnology, Medical Device
Series A, Seed, Series B
United States, Canada, Israel

Portfolio highlights

Aria CV — Learn about Aria CV's novel implantable medical device designed to treat pulmonary hypertension (PH). Our elegant device has no battery, pump, or electronics.
Alveron Pharma — Alveron produces drugs such as cyclodextrins, pro-coagualant cyclodextrins with a unique coagulation platform technology.
Relief Cardiovascular — Relief Cardiovascular is an inQB8 medical technologies portfolio company developing a revolutionary smart implant to decongest heart failure patients.

CincyTech helps to identify and transform innovation into venture-worthy, transformational human health and technology companies, primarily in southwest Ohio. Our team provides advice and capital to entrepreneurs, helps research institutions commercialize technology through startups, and catalyzes investment from individuals and institutions intoregional companies. One of the most active seed funds in the Midwest, CincyTech is supported by Ohio Third Frontier, more than two dozen foundations, corporations, municipalities and individuals as well as founding partners, Cincinnati Children’s Hospital Medical Center, the University of Cincinnati, and the Cincinnati USA Regional Chamber.

Investment focus

Software, Health Care, Biotechnology
Seed, Series A, Series B
United States

Portfolio highlights

Amify — We help brands selling on Amazon maximize sales and profitability by providing complete strategy, management and operational services.
Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
TeamCentral — TeamCentral is a company focused on optimizing productivity through improvements in how data is managed and governed across business systems.

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

Investment focus

Health Care, Software, Biotechnology
Seed, Pre-Seed, Grant
United States, Canada, United Kingdom

Portfolio highlights

Atme — Send anonymous messages to drivers using license plates. Free, safe, instant communication for DC, Maryland & Northern Virginia. Join thousands building safer roads.
Keep Company — Keep Company is a coaching community for parents & caregivers.
Astek Diagnostics — Saving lives through antibiotic sensitivity precision diagnostics

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

North Coast Ventures (formerly North Coast Angel Fund) is comprised of four contributed capital funds with a focus on early-stage technology investments. Our membership consists of a number of Ohio's leading investors, entrepreneurs, and business leaders who are dedicated to accelerating early-stage ventures.North Coast Ventures members playan active role by generating deal flow, serving on due diligence teams, working with portfolio companies, or serving on the Investment Screening and Executive Committees. Through this involvement, our goal is to provide a supportive environment for our portfolio companies and ultimately enhance the performance of our Fund.Northeast Ohio has a long tradition of active and successful angel investing, but until recently, the success of this crucial form of funding has hinged on the efforts of a relatively small number of individual investors. As the region’s first professionally managed angel fund, North Coast Angel Fund works to improve the early-stage funding environment for both entrepreneurs and investors.

Investment focus

Health Care, Software, Medical Device
Series A, Seed, Funding Round
United States

Portfolio highlights

Narratize — Our generative AI software helps innovative enterprises quickly produce impactful, accurate, compelling communications and deliverables by distilling their ideas and expertise.
Redi.Health — Redi.Health is a healthcare technology company that develops health management platforms for patients. The company aims to connect patients with chronic diseases to patient support programs. These programs are created in partnership with pharmaceutical manufacturers and are always free to the patient.
OnStation — Productivity app for roadway workers and that provides instant jobsite location, access to plans and design, and a team chat platform.

Providing Flexible and Creative Financial Solutions to Middle Market Companies.

Investment focus

Biotechnology, Health Care, Medical
Debt Financing, Post-IPO Debt, Series B
United States, United Kingdom, Canada

Portfolio highlights

Amino — Amino's digital healthcare guidance platform provides a fast, easy way to find a doctor, book appointments, and access health benefits.
Headspace — Live a healthier, happier, more well-rested life in just a few minutes a day. Get the science-backed mental health app for every moment. Try for free.
Pearl Street Dental Management — Pearl Street Dental Management supports non-clinical operations. They provide centralized services such as human resources, payroll, accounting, bookkeeping, finance, lending, facilities management, and information technology services. They address inquiries through online applications, phone calls, and emails.

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
VeraDermics — VeraDermics Inc. is a dermatology pharmaceutical start-up, makers of WartPatch
PHȲND — PHȲND is a subscription-free cloud gaming platform that offers a way to discover, play, and socialize across a wide variety of games.

Early Stage Venture Investments

Investment focus

Health Care, Medical Device, Software
Seed, Convertible Note, Series A
United States, Canada, Hungary

Portfolio highlights

Flourish Collective — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

Investment focus

Software, Health Care, Biotechnology
Seed, Funding Round, Series A
United States

Portfolio highlights

HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

FreeNav, Inc. — FreeNav is simplifying and standardizing the position tracking of procedural instrumentation for medical applications and procedures.
Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The groupâ€™s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The groupâ€™s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

Investment focus

Biotechnology, Health Care, Medical Device
Angel, Seed, Series A
United States, Canada, India

Portfolio highlights

Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

For over 20 years we have been a successful healthcare venture capital firm rooted in the Midwest. Check out our portfolio companies.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Canada, Israel

Portfolio highlights

Allay Therapeutics — SUPPORTING PATIENTS THROUGH EVERY PHASE OF RECUPERATION The first technology designed to deliver weeks of localized pain management
Shoulder Innovations — Shoulder Innovations addresses the most significant issue in shoulder arthroplasty: unreliable fixation of the glenoid implant.
Akadeum Life Sciences — Akadeum Life Sciences, Inc. Changing the way Cell Sorting & Cell Isolation is performed. Contact Us for faster & higher viabile Cell Separation Technology

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

Investment focus

Health Care, Software, Information Technology
Seed, Grant, Debt Financing
United States

Portfolio highlights

CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
SFA Therapeutics — SFA Therapeutics is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.
Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Convertible Note
United States, France, Israel

Portfolio highlights

Aralez Bio — Aromatic noncanonical amino acids that are made using biocatalysis. Single step, enzyme synthesis makes hundreds of tryptophan and other amino acid analogs!
AdipoPharma — AdipoPharma SAS is dedicated to learning more about the role of adipocyte cells in diabetes. AdipoPharma is using the adipocyte's power to treat insulin resistance, type 2 diabetes, and other diseases.
Hoofprint Biome — Hoofprint Biome, developing probiotics for to increase feed digestibility and decreasing methane in cattle

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

Granite Bio — Targeting fundamentals of Inflammation, Autoimmunity and Fibrosis. Granite Bio develops first-in-class therapeutic antibodies depleting pathogenic cells with the potential to transform inflammatory and fibrotic diseases.
Helicore Biopharma — Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders.
Kriya Therapeutics — Kriya is a biopharmaceutical company developing gene therapy to address common diseases that impact millions of people worldwide. Learn more.

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Inkeep — inkeep provides conversational search for developer-focused companies. We use LLMs to understand a company’s docs, GitHub issues, Stack Overflow threads and more to answer developer questions and increase customer activation.
Aven — Inventing new ways to save people money
Cognition — Cognition is an applied artificial intelligence lab that focuses on reasoning and code.

For over two decades, Sand Hill Angels has worked openly and collaboratively with venture capital funds, other angel organizations, and the Bay Area ecosystem that fosters the growth of technology startups.

Investment focus

Health Care, Software, Biotechnology
Seed, Series B, Series A
United States, Canada, Japan

Portfolio highlights

TrueMeter — EcoTrove is your energy concierge for cheaper, greener and more predictable power bills.
Logomix — Logomix Inc is a mammalian cellular genome architect startup. Logomix proprietary platform, Geno-Writing™, technology integrates large-scale (Mb) human genome-writing technologies and providing genetically architected versatile human cells and/or downsized cells and microbes for drug development and cell & gene therapy area.Majority ofthe cell engineering companies are currently focused on optimization of gene clusters by automatic high throughput system however, Logomix’s Geno-Writing™ provides the required tools for dealing with mammalian or complex genomes. Logomix works with partners by providing new biology-based solutions to co-create business and social values on Geno-Writing™ platform Current Focus Area includes: 1. Human Health & Therapeutics 2. Biomaterials & Chemicals 3. Agriculture & EnvironmentLogomix has 11 ongoing collaborative research partnerships. Currently Logomix is specifically looking for industry partners to address unmet needs in neurodegenerative disease areas.
Lōvu Health — Lōvu Health is a digital maternal health platform that offers services to care for mother and baby from conception to postpartum.

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

Investment focus

Health Care, Medical Device, Medical
Series A, Series B, Series C
United States

Portfolio highlights

Epitel — Epilog is an unobtrusive wearable seizure detection system that records long-term EEG, anywhere. It gives people living with epilepsy peace of mind with a much-needed tool to better understand and manage their seizures.
Avive Solutions — Avive Solutions develops a next-generation Automated External Defibrillator (AED) and software solutions. Avive's AED enables anyone to positively impact the outcome of a Sudden Cardiac Arrest (SCA) rescue by building a more robust solution that addresses the problem of SCA in its entirety. The AED will remove barriers to respond to a SCAscenario. It will be easy to purchase, easy to access in an emergency, easy to keep maintained, and most importantly easy to use effectively when it matters most.Avive Solutions is headquartered in San Francisco, California.
PanTher Therapeutics — PanTher Therapeutics is on a mission to revolutionize cancer care with a proprietary treatment platform designed to enhance therapeutic response with minimal side effects. PanTher’s highly adaptable platform empowers oncologists to treat patients with life-threatening cancer by unlocking a drug’s full potential through direct, sustained treatmentat the tumor site. This distinctive targeting capability uniquely positions PanTher to take on the deadliest and most difficult to treat cancers with a lead investigational candidate in pancreatic cancer.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Medical
Seed, Funding Round, Series A
United States, Canada, France

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

DropCap — We are an innovative foreign rights literary agency that elevates exceptional books to the worldwide stage.
Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Life Science Angels, Inc. (LSA) is the premier angel investment group focused solely on healthcare investing, including medical devices, diagnostics, pharmaceuticals, biotechnology, and digital health.

Investment focus

Biotechnology, Health Care, Medical
Funding Round, Seed, Series A
United States, Israel, The Netherlands

Portfolio highlights

Neurava — Neurava has developed wearable diagnostics for epilepsy patients including those at risk of SUDEP. The company specializes in the fields of medical device manufacturing, healthcare, and health diagnostics.
Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

Investment focus

Health Care, Medical Device, Medical
Series B, Series A, Series C
United States

Portfolio highlights

AtaCor Medical — AtaCor Medical Inc., is a San Clemente-based medical device maker. It designs innovative solutions to deliver temporary, interim, and permanent cardiac pacing when, and where it matters most.
Venova Medical — Venova Medical, Inc. is a privately held company addressing the challenges associated with providing optimal vascular access for patients that need hemodialysis.
Brixton Biosciences — Brixton Biosciences is a biotechnology company currently operating in stealth mode.

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, United Kingdom, Israel

Portfolio highlights

Alkymi — Alkymi is an intelligent data processing and workflow automation solution designed to empower business users. We help free huge volumes of data from emails and documents to accelerate decision-making.
Field AI — Field AI develops autonomy software that equips mobile robots with a universal, risk-aware brain. It offers Field Foundation Models™ (FFMs) that enable embodiment-agnostic operation across legged, wheeled, flying, and tracked platforms. The company’s technology empowers robots to work safely in dynamic, unmapped environments, without reliance onGPS, pre-programmed routes, or maps, operating fully at the edge in real-time. Robots using this software can be deployed across industries such as construction, energy, mining, agriculture, urban operations, manufacturing, power and utilities, and federal applications, among others.
Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.

Tech Coast Angels is the largest angel investor group in the United States, possessing more than 300 members in five networks in Los Angeles, Orange County, San Diego, Central Coast, and the Inland Empire. Its members provide funding and guidance to more early-stage, high-growth companies in Southern California than any other investment group.Members invest in companies in a wide range of industries, including the life sciences, biotech, IT, services, retail, Internet, financial, software, media, consumer products, and tech startups. TCA as a whole gives companies more than just capital; they also provide counsel, mentoring, and access to an extensive network of potential investors, customers, strategic partners, and management talent. Tech Coast Angels has been ranked by CB Insights to be among the Top 20 Angel Groups in the US; TCA was also ranked as #1 for Network Centrality, meaning we have more connections than anyone! If you are in the game-changing business, we are here to help.

Investment focus

Software, Health Care, Biotechnology
Seed, Convertible Note, Funding Round
United States, Canada

Portfolio highlights

Giftpack — Giftpack's AI-powered solution simplifies the corporate gifting process and amplifies the impact of personalized gifts. We're crafting memorable touchpoints by sending personalized gifts selected out of a curated pool of 3 million options with just one click. Our AI technology efficiently analyzes each recipient's social media,cultural background, and digital footprint to customize gift options at scale. We take care of generating, ordering, and shipping gifts worldwide. We're transforming the way people build authentic business relationships by sending smarter gifts faster with gifting CRM.
Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
Nob Hill Therapeutics — Nob Hill Therapeutics is a Delaware Corporation, founded to develop and market DryNeb, a first-in-kind dry powder nebulizer to address large pulmonary drug delivery market opportunities. The company has exclusively licensed the technology from the University of New Mexico.DryNeb™ vs. Aerosol Mist Nebulizers Compact, handheld, portable DryNeb willreplace cumbersome aerosol mist nebulizers.The pulmonary route of drug delivery has been gaining much importance in the present day, as it enables targeted drug delivery directly to the lungs for both local and systemic treatment. Pulmonary drug delivery, as a noninvasive drug administration method, is characterized by its high bioavailability and fast action. It is increasingly used in modern clinical practice for improved treatment of local as well as systemic diseases.

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

Investment focus

Software, Health Care, Information Technology
Series B, Series C, Series A
United States, Israel, Canada

Portfolio highlights

Iantrek — Iantrek develops technology for minimally invasive microinvasive glaucoma surgery. It was founded in 2019 and is based in White Plains, New York.
TinyFish — Tiny Fish is an AI startup empowers machines to communicate and collaborate. Stealth mode.
Neuros Medical — Neuros Medical is a neuromodulation company, is focused on developing proprietary therapies for the unmet needs of patients worldwide. The Company's patented platform technology, Electrical Nerve Block, is focused on the elimination of chronic pain in a variety of applications including neuroma/residual limb pain, chronic post-surgicalpain, and chronic migraine.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

Mana.bio — Mana.bio is an AI based drug delivery startup, focusing on gene therapy including RNA and DNA-based therapeutics and vaccines
ZeroMark — ZeroMark is a defense product company building technology to ensure safety and precision when using kinetic and non lethal weapons.
Wild West Systems — Wild West Systems is a Defense and Space Manufacturing firm developing weapon systems for the future war.

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

Investment focus

Health Care, Biotechnology, Software
Series A, Seed, Series B
United States, Cyprus, Ireland

Portfolio highlights

basys.ai — Reducing administrative burden in healthcare through secure, interpretable, and adaptive AI workflows. AI-Powered Prior Auth & Provider Workflow Automation. Streamline prior authorization with Basys AI-driven UMAI solutions for provider workflow automation. Ideal for health plans, RFPs, and digital transformation.
Autonomize AI — AI Copilots for Healthcare & Life Sciences. Empower knowledge workers, reduce administrative burden and improve health outcomes.
Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.

Horizon is a venture lending platform that offers structured debt products to life science and technology companies. Its team of investment and operations professionals has been providing debt capital to some of the most exciting companies for decades. The members of the Horizon team have, collectively, originated and invested more than $5 billionin venture loans to thousands of companies.The company was founded in 2003 and is headquartered in Farmington, Connecticut.

Investment focus

Health Care, Biotechnology, Medical Device
Debt Financing, Post-IPO Debt, Funding Round
United States, Canada, India

Portfolio highlights

Finexio — Accounts Payable Software | B2B Payments.
Onkos Surgical — Onkos Surgical is a privately-held surgical oncology company that brings new technology and solutions to surgical oncologists. There are huge opportunities for innovation where the complexity of the disease state requires more diverse solutions. Onkos Surgical will be 100% focused on bringing new technology and solutions to surgical oncologists whoserve a population of which a large portion of the patients are children and the broader population may require personalized solutions.
Ursa Space Systems — We are a U.S.-based satellite intelligence company that provides business and government decision-makers access to on-demand analytic solutions. Through our radar satellite network and data fusion expertise, Ursa Space detects real-time changes and analyzes patterns in the physical world to understa

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
Hippocratic AI — The First Safety Focused LLM for Healthcare

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
United States, Germany

Portfolio highlights

Nichefire — Nichefire is an AI-power marketing analytics company.
SureImpact — SureImpact is a user-friendly, social services case management software that helps you track and report outcomes, measure participant needs, and demonstrate impact to funders.
HealthPlan Data Solutions — The HDS technology platform offers multiple solutions to help key stakeholders across the pharmacy spectrum ensure every claim adheres to the PBM contract and plan design, delivering more effective pharmacy benefit cost management.

ShangBay Capital is a venture capital company that brings best-in-class investments mainly in the U.S. medical devices technology, as well as biotech, and mobile healthcare sectors through early-stage venture equity participation

Investment focus

Health Care, Medical Device, Biotechnology
Series A, Series B, Funding Round
United States, China, Canada

Portfolio highlights

Fluid Biomed — Fluid Biotech is a Calgary based company that aims to develop the next generation of stents to improve patient well-being and realise better health and quality of life through innovation.
Inquis Medical — Inquis Medical is a privately funded medical device company dedicated to advancing the treatment of venous thromboembolic diseases.
Venova Medical — Venova Medical, Inc. is a privately held company addressing the challenges associated with providing optimal vascular access for patients that need hemodialysis.

The St. Louis Arch Angels is a network of accredited investors who fund early-stage businesses across the St. Louis region.

Investment focus

Biotechnology, Health Care, Medical Device
Seed, Series A, Funding Round
United States, Argentina

Portfolio highlights

Peptyde Bio — Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.
SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
Maximum Fidelity Surgical Simulations — The most realistic surgical and trauma simulations for surgeons, forward field operators, medics and medical device development.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Canada

Portfolio highlights

HistoSonics — HistoSonics provides the Edison Platform, which uses advanced imaging and proprietary sensing technology to deliver non-invasive, personalized treatments with precision and control, and uses the science of histotripsy and focused sound energy to generate pressures to liquify and completely destroy targeted tissues at sub-cellular levels.
Atsena Therapeutics — Atsena is a clinical-stage gene therapy company, focused on bringing the life-changing power of genetic medicine to reverse or prevent blindness.
GeneCentric Therapeutics — GeneCentric Therapeutics engages in developing and commercializing molecular diagnostic tests for oncologists and patients. The company currently has two unique platform technologies including The Lung Subtype Platform (LSP) stratifies lung cancer patients into subtypes, which are important for appropriate therapeutic selection. The firstapplication of LSP was licensed to and independently developed by Laboratory Corporation of America Holdings (“LabCorp”) and is now available through its specialty testing business, Integrated Oncology, as HistoPlusSM: Lung Cancer. Its second platform technology is the Hypoxia Signature which has the potential to identify patients that respond to anti-angiogenesis therapies.GeneCentric utilizes a unique partnership model to translate important cancer discoveries into clinically adopted diagnostics for pathologists, clinicians, and, most importantly, patients. The company was incorporated in 2011 and is based in Durham, North Carolina.

Privately Held Companies

Investment focus

Health Care, Medical, Biotechnology
Series A, Series B, Series C
United States, Canada, Australia

Portfolio highlights

Ten Bay Bio — Ten Bay Bio is a biotechnology company that offers biological therapies for treatment of complex diseases in immunology.
Apreo Health — Apreo Health is developer of medical apparatus designed for diagnosing or treating respiratory, pulmonary, and lung conditions.
Solu Therapeutics — Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells.

Connecting Entrepreneurs and Investors Since 1985.

Investment focus

Software, Health Care, Medical Device
Seed, Series A, Convertible Note
United States, Canada

Portfolio highlights

MyUTI — Discover fast, reliable, easy at home testing with MyUTI. Our proven PCR testing for UTIs, BV and STIs delivers accurate results, test from the comfort of your home. Get care from home with our discreet and direct UTI lab test service.
Pure Blue Tech Inc. — Pure Blue Tech uses ultrasonic technology to reduce membrane fouling and can significantly lower the costs associated with membrane maintenance and replacement. The elements will allow industrial companies and municipalities to filter and purify more water, wastewater, seawater, milk, and other liquids with less money. They provide maintenance,chemicals, downtime, and waste disposal. They serving systems and plants treating.
Green Steel Environmental — Developer of sustainable clean products designed to clean hydrogen sulfide into renewable gas. The company uses clean tech upcycled materials to remove excess nutrients from wastewater and renewable natural gas, enabling returns of those nutrients to the earth as fertilizer.

The Vertical Group is a New Jersey-based venture capital firm focused on the fields of medical technology and biotechnology.

Investment focus

Health Care, Medical Device, Medical
Series B, Series C, Funding Round
United States, Israel

Portfolio highlights

Luminopia — Luminopia is the first FDA-approved binocular therapy for amblyopia.
MicroTransponder — MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas.
Route 92 Medical — The official website for Route 92 Medical.

Providing funding and expertise for early-stage medical device companies.

Investment focus

Health Care, Medical Device, Medical
Series C, Series A, Series B
United States, France

Portfolio highlights

Shape Memory Medical — Smart polymer. Smart embolization. Smart choice. Reshaping your view of clinical success through the science of smart polymer.
Standard Bariatrics — Cincinnati-based surgical procedure company focused on innovative development, commercialization of medical devices for treatment of obesity, gastrectomy.
Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.

New York Angels is one of the oldest, most prominent angel investment groups in the country. New York Angels has offered early-stage entrepreneurs funding, mentoring, connections and more for over 20 years. Angel investors join New York Angels for their extensive, experienced network, increased de

Investment focus

Software, Health Care, Mobile
Seed, Series A, Series B
United States, Israel, United Kingdom

Portfolio highlights

Goldilock — Goldilock is a revolutionary cybersecurity solution that enables users to physically connect and disconnect their digital assets, devices, networks, and critical infrastructure from the internet without using the internet itself. The patented remote security technology ensures that sensitive data remains secure and accessible only when needed
Aline — A tool for modern organizations to digitally transform their contract processes.
Diadem Capital — Diadem Capital is a curated marketplace for venture debt and venture capital. Connecting founders with venture capital funds, family offices, & corporate VCs.

Three Arch Partners was formed in 1993 to provide young companies with access to relevant clinical and business resources, as well as capital. Three Arch has helped create, build and fund more than 100 important new healthcare companies. These companies have often become the clinical and market leaders in their respective fields, and have generatedstrong returns. The fund focuses on opportunities in medical devices and healthcare services, and less frequently in biotechnology.

Investment focus

Health Care, Biotechnology, Medical Device
Series B, Series C, Funding Round
United States, Belgium

Portfolio highlights

Nevro — Nevro is a global medical device company focused on providing innovative products that improve the quality of life of patients suffering from debilitating chronic pain. Nevro has developed and commercialized the Senza spinal cord stimulation (SCS) system, an evidence-based neuromodulation platform for the treatment of chronic pain. The Senza systemis the only SCS system that delivers Nevro's proprietary HF10 therapy. Senza, HF10, Nevro and the Nevro logo are trademarks of Nevro.
Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
Access Closure — Access Closure, Inc., a medical device company, provides access site management products to address the complex challenge of vascular closure during interventional and diagnostic procedures. The company's products include Mynx delivery system, a vascular closure device that seals the arteriotomy using a water-soluble and extravascular sealant,which expands in the tissue tract by absorbing blood and subcutaneous fluids. Access Closure, Inc. was founded in 2002 and is based in Mountain View, California.

Keiretsu Forum is a global angel investor network with more than 2,500 accredited investor members throughout 47 chapters on 3 continents.

Investment focus

Health Care, Software, Biotechnology
Funding Round, Seed, Series A
United States, India, Turkey

Portfolio highlights

ALM Ortho — ALM Ortho, Osseointegration for Patient Matched Orthopedic Implant Solutions
ActuatedMedical — Actuated Medical designs innovative medical devices that improve patient care and outcomes by solving unmet clinical needs with engineered motion.
Kisaan Se Kitchen Tak — Eat our pure, naturally grown, & direct farmse products, grown without use of harmful chemicals brought to directly from Kisaan Se Kitchen Tak; they'll fill your body with energy, nutrients, & antioxidants.

Alumni Ventures Group provides high-quality, diversified venture portfolios to individual investors who previously haven't had access to VC.It helps accredited alums from top entrepreneurial schools invest together in the ventures of fellow alums. The firm backs companies with an alumni connection and an institutional lead investor withexpertise in the space. AVG also offers focused funds that allow any accredited investor access to a venture portfolio, diversified by type, sector, stage, and geography.Beth Obermiller, Michael Madden, and Mike Collins co-founded the firm in Manchester, New Hampshire in 2013.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Kognitos — Kognitos is in stealth mode.
CRED — Compare millions of commercial data points and uncover unique and personalised opportunities for your brand.
Spekter Games — Spekter Games offers well-tested free-to-play Web2 mobile games that have been improved with a skillfully designed Web3 incentive layer, as well as chat-based super apps.

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Investment focus

Health Care, Biotechnology, Pharmaceutical
Series B, Series C, Series A
United States, Germany, Switzerland

Portfolio highlights

Paperspace — Ceres, Inc. (Ceres) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks. The Company’s large-scale commercial products are sweet sorghum varieties that can be used as a drop-in feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills. Its products include sweet sorghum, high biomasssorghum, switchgrass, miscanthus and row crops. Its energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Baseload utility scale electric power can also be generated from the biomass feedstocks grown from its seeds. Ceres has sold switchgrass and high biomass sorghum seeds in the United States under its Blade Energy Crops (Blade) brand. In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda.
CardioFocus — CardioFocus is a biotechnology company that focuses on the advancement of ablation treatments for cardiac disorders. The company specializes in providing electrophysiologists with innovative and effective tools that bring new levels of precision and control to the treatment of atrial fibrillation that focuses on developing, manufacturing, andinvestigating disposable fiber optic catheters for the visualization of the cardiac anatomy and the treatment of cardiac arrhythmias.CardioFocus was founded in 1990 and is headquartered in Marlborough, Massachusetts.
Yolia Health — Yolia Health developed The True Vision Treatment or TVT, the 'Invisalign' for the eyes. A non-invasive treatment to correct vision problems like presbyopia without surgery. TVT is self-administered by the patient in his or her own home. It employs a combination of customized contact lenses (TVT Contacts) and specially formulatedeye drops (TVT Eye Drops). After only 5 days of treatment with TVT patients are able to stop using the TVT Contacts, TVT Eye Drops and their reading glasses for up to 12 months at a time before re-treatment with TVT is needed. What is even greater than correcting for presbyopia non-invasively, is correcting both eyes without compromising any distance vision. On the contrary, Yolia's treatment improves both near and distance vision, a unique feature no single other alternative can provide. ** Looking for sophisticated investors and key industry partners.

DeNovo Ventures was formed in 2000 by seasoned investors and experienced medical device entrepreneurs who sought to share the lessons learned from a history of successful investing and building successful companies. They believed that their unique combination of skills and perspectives could help entrepreneurs to build companies which would havesignificant clinical impact and generate superior returns. Seven years later, this belief continues to hold true, demonstrated by investment success in selected medical device and biotechnology companies. With $650 million under management, De Novo has made more than 40 investments in medical devices and biotechnology across three funds. They invest in all stages of enterprise development and growth â€“ from early stage to late stage. The unique background of leading companies as entrepreneurs and operating executives from start to exit enables us to advise entrepreneurs and management teams over the full life cycle of the company.

Investment focus

Health Care, Medical Device, Biotechnology
Series B, Series D, Series C
United States

Portfolio highlights

Avedro — Glaukos works relentlessly to create and deliver transformative therapies for patients struggling with glaucoma, corneal disorders, and retinal diseases.
Milo — Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.
Spinal Kinetics — The artificial disc replacement device from Orthofix is changing the lives of people suffering from spinal pain. Learn about this motion-saving product.

Keiretsu Capital LLC is an affiliate of the World's Leading Angel Network, Keiretsu Forum, and manages funds which enable limited partners to co-invest in the proprietary deal flow of the angel investors.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series A, Seed
United States, Canada, India

Portfolio highlights

Clensta — Clensta is a biotechnology start-up to improve the National Hygiene condition whilst addressing the aspect of water conservation. Clensta is an Indian startup and in association with IIT Delhi, works to create innovative healthcare solutions to make hygiene accessible for anyone, anytime, and anywhere. Driven by their aim to create products thatpromote complete cleaning solutions without water.
Healionics — Healionics aims to provide safer, more reliable means of bloodstream access for dialysis in patients with kidney failure.
Another Tomorrow — Discover consciously crafted wardrobe icons : sustainable, and ethically made. Enjoy flat rate international shipping, free shipping in the US, and easy returns. Explore our new arrivals and join our list for exclusive access to future collections.

Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Funding Round
United States, Canada, France

Portfolio highlights

Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.