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Top 50 Medical Device Startup Investors in United States (July 2026)

The most active venture capital funds and angel investors investing in United States Medical Device startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Medical Device startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Innova Memphis
VC Fund
71 United States, Argentina, United Kingdom Seed, Pre-Seed Health Care, Medical, Medical Device $25k–$1.7M
TEDCO
VC Fund
25 United States, Canada, Colombia Seed, Grant, Pre-Seed Health Care, Software, Biotechnology $25k–$2.5M
Portfolia
VC Fund
21 United States, Canada, Romania Seed, Series A, Series B Health Care, Biotechnology, Software $347k–$59M
SOSV
VC Fund
20 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
HealthTech Capital
VC Fund
19 United States, Canada Seed, Series A, Convertible Note Health Care, Medical Device, Medical $1M–$15M
Broadview Ventures
VC Fund
18 United States, Switzerland, Canada Series A, Seed, Series B Health Care, Biotechnology, Medical Device $1M–$45M
CincyTech
VC Fund
18 United States Seed, Series A, Series B Software, Health Care, Information Technology $250k–$30M
New York Angels
VC Fund
17 United States, Israel, United Kingdom Seed, Series A, Series B Software, Health Care, Mobile $517k–$19M
Gaingels
VC Fund
17 United States, Canada, Mexico Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1.1M–$100M
Alumni Ventures
VC Fund
17 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.5M–$79M
Arboretum Ventures
VC Fund
16 United States, Canada, Israel Series B, Series A, Series C Health Care, Biotechnology, Medical $4.4M–$80M
North Coast Ventures
VC Fund
16 United States Series A, Seed Health Care, Software, Medical Device $350k–$10M
Wavemaker 360
VC Fund
16 United States, United Kingdom, Canada Seed, Series A, Series B Health Care, Medical, Artificial Intelligence $750k–$30M
Maine Angels
VC Fund
15 United States Seed, Series A Health Care, Software, Biotechnology $25k–$5.9M
Texas HALO Fund
VC Fund
15 United States, Canada, Hungary Seed, Convertible Note, Series A Health Care, Medical Device, Software $105k–$10M
MB Venture Partners
VC Fund
15 United States, Israel Seed, Series B, Series C Health Care, Medical, Medical Device $50k–$28M
Oxford Finance LLC
VC Fund
15 United States, United Kingdom, Canada Debt Financing, Post-IPO Debt, Series B Biotechnology, Health Care, Medical $7.5M–$150M
Connecticut Innovations
VC Fund
15 United States, Israel, Canada Seed, Series A Health Care, Biotechnology, Software $300k–$25M
Good Growth Capital
VC Fund
14 United States, France, Israel Seed, Series A, Convertible Note Health Care, Biotechnology, Software $25k–$20M
Life Science Angels
VC Fund
14 United States, Israel, The Netherlands Seed, Series A Biotechnology, Health Care, Medical $1M–$20M
Golden Seeds
VC Fund
14 United States, Canada Series A, Seed, Series B Health Care, Software, Biotechnology $740k–$20M
Boston Harbor Angels
VC Fund
14 United States, Canada, India Angel, Seed, Series A Biotechnology, Health Care, Medical Device $100k–$6M
Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund
13 United States Seed, Grant, Debt Financing Health Care, Software, Information Technology $5k–$2.2M
Versant Ventures
VC Fund
13 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $4.7M–$108M
Catalyst Health Ventures
VC Fund
13 United States Series B, Series A, Series C Health Care, Medical Device, Medical $1.3M–$85M
Right Side Capital Management
VC Fund
13 United States, Canada, United Kingdom Seed, Pre-Seed, Convertible Note Software, SaaS, Health Care $20k–$2M
Khosla Ventures
VC Fund
13 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, Health Care $2M–$100M
Sand Hill Angels
VC Fund
13 United States, Canada, Japan Seed, Series A, Series B Health Care, Software, Biotechnology $1M–$100M
Keiretsu Forum
VC Fund
12 United States, India, Turkey Seed, Series A Health Care, Software, Biotechnology $102k–$8.6M
Wisconsin Investment Partners
VC Fund
12 United States, Canada, United Kingdom Seed, Series A Health Care, Biotechnology, Medical $400k–$7M
Rev1 Ventures
VC Fund
12 United States, Germany Seed, Series A Software, Health Care, Information Technology $192k–$18M
Boutique Venture Partners
VC Fund
12 United States, Canada, France Seed, Series A, Pre-Seed Health Care, Medical, Biotechnology $2.5M–$31M
Everywhere Ventures
VC Fund
12 United States, Australia, India Pre-Seed, Seed, Series A Software, Health Care, FinTech $550k–$60M
U.S. Venture Partners
VC Fund
12 United States, Israel, Canada Series B, Series C, Series A Software, Health Care, Information Technology $5M–$67M
Horizon Technology Finance
VC Fund
12 United States, Canada, India Debt Financing, Post-IPO Debt Health Care, Biotechnology, Medical Device $5M–$40M
Houston Angel Network
VC Fund
11 United States, Canada, France Seed, Series A Health Care, Software, Medical $25k–$5M
Kleiner Perkins
VC Fund
11 United States, China, United Kingdom Series B, Series A, Series C Software, Health Care, Information Technology
Hatteras Venture Partners
VC Fund
11 United States, Canada Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$90M
Asset Management Ventures (AMV)
VC Fund
11 United States, Cyprus, Ireland Series A, Seed, Series B Health Care, Biotechnology, Medical $500k–$35M
Third Rock Ventures
VC Fund
11 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $11M–$190M
St. Louis Arch Angels
VC Fund
11 United States, Argentina Seed, Series A Biotechnology, Health Care, Medical Device $100k–$8.5M
TCA Venture Group
VC Fund
11 United States, Canada Seed, Convertible Note Health Care, Software, Biotechnology $50k–$7M
Mayo Clinic
VC Fund
11 United States, Canada, Israel Series A, Seed, Series B Health Care, Biotechnology, Medical $100k–$100M
The Vertical Group
VC Fund
10 United States, Israel Series B, Series C Health Care, Medical Device, Medical $1.5M–$77M
Three Arch Partners
VC Fund
10 United States, Belgium Series B, Series C Health Care, Biotechnology, Medical Device
Emergent Medical Partners
VC Fund
10 United States, France Series C, Series A, Series B Health Care, Medical Device, Medical
Oxford Bioscience Partners
VC Fund
10 United States, Germany, Switzerland Series B, Series C, Series A Health Care, Biotechnology, Pharmaceutical $3.5M–$50M
Morgenthaler Ventures
VC Fund
10 United States, Canada, France Series B, Series A Health Care, Biotechnology, Medical
Rockies Venture Club
VC Fund
10 United States, Canada Seed, Series A, Convertible Note Software, Health Care, Medical Device $250k–$7M
DeNovo Ventures
VC Fund
10 United States Series B, Series D, Series C Health Care, Medical Device, Biotechnology
Access all 4731 investors in United States Medical Device startups.

Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Innova Memphis
VC Fund · Memphis, Tennessee, United States · 71 investments in United States Medical Device startups

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Pre-Seed
  • Geography: United States, Argentina, United Kingdom

Investor stats

  • Total investments: 252
  • Round size: Seed $50k–$1.7M; Pre-Seed $25k–$1.3M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
  • Insignum AgTech — Insignum AgTech develops biotech plants that communicate with producers, alerting them to an illness in its early stages.
  • Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.
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TEDCO
VC Fund · Columbia, Maryland, United States · 25 investments in United States Medical Device startups

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Grant, Pre-Seed
  • Geography: United States, Canada, Colombia

Investor stats

  • Total investments: 288
  • Round size: Seed $100k–$2.5M; Grant $50k–$1M; Pre-Seed $25k–$900k
  • Lead/follow: 67% lead, 33% follow

Portfolio highlights

  • Omni Biosciences — Omni Biosciences is a minority women-owned biotechnology company.
  • Nodal Therapeutics — Nodal Therapeutics is a venture-backed startup developing next-generation antigen-specific tolerance technology to stop autoimmune disease.
  • Allegany College of Maryland — The main campus of the Allegany College of Maryland rests in Cumberland, off of Willow Brook Road. As the biggest of the school’s three campuses, Cumberland has all of the amenities you may never have expected from a small college. Each building is equipped with the latest modern facilities, making for an up-to-date learning experience. There arealso dining areas, a student lounge, and a state of the art physical education building with a gym and swimming pool.Within the list of extensive fields of study are the social, biological and political sciences, criminal justice and criminology, many fields in the humanities, accounting and business programs, automotive and other technical studies, culinary arts, hotel and restaurant management, forest technology, health fields including dental hygiene, physical education, nursing, and pharmacy technician studies, and more. Advice is not something you’ll be lacking at Allegany. The tutoring services can help you through any academic rough patches. Transfer advising can prepare you to go to a four-year college. Career advising counselors can help you pick a major, assess your interests and aptitudes, and help find you a career.Along with federal financial aid and veteran’s benefits, Allegany also offers a catalog full of scholarships from major related aid to local endowments to eligible students.
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Portfolia
VC Fund · San Mateo, California, United States · 21 investments in United States Medical Device startups

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Romania

Investor stats

  • Total investments: 187
  • Round size: Seed $1.2M–$4.3M; Series A $347k–$15M; Series B $9M–$59M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely still investing — raised $722k in 2022

Portfolio highlights

  • Schola — Schola helps families find and enroll in the ideal PreK-12 schools.
  • Aria CV — Learn about Aria CV's novel implantable medical device designed to treat pulmonary hypertension (PH). Our elegant device has no battery, pump, or electronics.
  • Health Hero — Conscious health engagement for patients, employees, and health plan members. A digital platform elevating one's health by promoting a natural way of life considering the social determinants of health - by delivering engaging, simple, & personalized programming through any medium.
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SOSV
VC Fund · Princeton, New Jersey, United States · 20 investments in United States Medical Device startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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HealthTech Capital
VC Fund · Los Altos Hills, California, United States · 19 investments in United States Medical Device startups

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 95
  • Round size: Seed $1M–$3.4M; Series A $1.6M–$15M
  • Lead/follow: 11% lead, 89% follow

Portfolio highlights

  • S2 Genomics — S2 Genomics is developing spatial sequencing technology solutions for processing solid tissues for single-cell applications. It enables automated processing of raw tissues into single cells or nuclei for genomics and cell biology studies. The company's vision is to provide products that process raw tissues into samples ready for genomicanalyses.S2 Genomics was founded in 2016 and is headquartered in Livermore, CA.
  • Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
  • GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
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Broadview Ventures
VC Fund · Boston, Massachusetts, United States · 18 investments in United States Medical Device startups

Broadview Ventures, Inc. (Broadview) was established in 2008 as a new program conceived by the Leducq family. Through Broadview, the trust will work to accelerate the development of promising technology in cardiovascular and neurovascular disease through targeted investment in and support of early stage technology ventures.The FoundationLeducq, based in Paris, France, is the beneficiary of a charitable trust. In order to further the Foundation Leducq's mission in cardiovascular and neurovascular disease, the trust has made funds available to Broadview to develop a program which will promote early state technology in these fields through investments, licensing agreements and consortium funding arrangements, as well as professional, management and consulting support.With this initiative the trust joins other leaders in the venture philanthropy movement in seeking creative solutions to the problem of what is commonly referred to as the 'translational gap', a significant component of which is a lack of funding at a critical moment in the development of new technology and science.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Series A, Seed, Series B
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 78
  • Round size: Seed $1M–$9.5M; Series A $1M–$30M; Series B $7M–$45M
  • Lead/follow: 29% lead, 71% follow

Portfolio highlights

  • Adient Medical — Medical Devices that Automatically Vanish - Adient Medical is leading the development of an absorbable vascular filter for the prevention of pulmonary embolism.
  • HAYA Therapeutics — Pioneering next-generation therapies for fibrotic diseases. Learn more about our approach here.
  • Mosanna Therapeutics — Mosanna is a Biotech company based in Basel with a commitment to improving patient outcomes and quality of life in high unmet need diseases, applying a precision medicine approach.
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CincyTech
VC Fund · Cincinnati, Ohio, United States · 18 investments in United States Medical Device startups

CincyTech helps to identify and transform innovation into venture-worthy, transformational human health and technology companies, primarily in southwest Ohio. Our team provides advice and capital to entrepreneurs, helps research institutions commercialize technology through startups, and catalyzes investment from individuals and institutions intoregional companies. One of the most active seed funds in the Midwest, CincyTech is supported by Ohio Third Frontier, more than two dozen foundations, corporations, municipalities and individuals as well as founding partners, Cincinnati Children’s Hospital Medical Center, the University of Cincinnati, and the Cincinnati USA Regional Chamber.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States

Investor stats

  • Total investments: 121
  • Round size: Seed $250k–$3.5M; Series A $300k–$30M; Series B $2.5M–$11M
  • Lead/follow: 55% lead, 45% follow
  • Last fund: Likely still investing — raised $12M in 2023

Portfolio highlights

  • Amify — We help brands selling on Amazon maximize sales and profitability by providing complete strategy, management and operational services.
  • Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
  • TeamCentral — TeamCentral is a company focused on optimizing productivity through improvements in how data is managed and governed across business systems.
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New York Angels
VC Fund · New York, New York, United States · 17 investments in United States Medical Device startups

New York Angels is one of the oldest, most prominent angel investment groups in the country. New York Angels has offered early-stage entrepreneurs funding, mentoring, connections and more for over 20 years. Angel investors join New York Angels for their extensive, experienced network, increased de

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Investment focus

  • Industry: Software, Health Care, Mobile
  • Stage:Seed, Series A, Series B
  • Geography: United States, Israel, United Kingdom

Investor stats

  • Total investments: 273
  • Round size: Seed $517k–$5M; Series A $1.2M–$9.2M; Series B $2M–$19M
  • Lead/follow: 41% lead, 59% follow
  • Last fund: May invest from a new fund soon — raised $1.2M in 2012

Portfolio highlights

  • Enertiv — Enertiv's is a CRE technology company that transforms building data into asset value. Top owners and operators have adopted Enertiv as their primary smart building technology and a key component in their overall PropTech strategy.
  • Epicured — Epicured delivers gourmet low-FODMAP, gluten-free meals by chefs for digestive health. Tasty cuisine right to your door.
  • Dirty Shirley
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Gaingels
VC Fund · New York, New York, United States · 17 investments in United States Medical Device startups

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 1006
  • Round size: Seed $1.1M–$8.1M; Series A $5M–$40M; Series B $16M–$100M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • BQP — BosonQ Psi Pvt. Ltd. (BQP) is a state-of-the-art SaaS-based enterprise software venture leveraging the power of Quantum computing to speed up virtual simulations of Multiphysics and Computer-Aided Engineering (CAE) nature. BosonQ Psi is at the forefront of this quantum revolution. Our vision is to become the premier multiphysics simulation softwareusing quantum computing. Our world-class software suite will include computational science fields of fluid dynamics, structural dynamics, thermal, chemical, and aeroacoustics. With such an innovative product, we will revolutionize the computational world by enabling high-fidelity simulations that are impossible to solve with current computing technology. Further, this product will aid aerospace, automotive, energy, manufacturing, biotechnology, civil engineering, and astrophysics industries in saving millions of dollars by reducing long turnaround times of simulations used in the design process and give higher accuracy to make significant design changes for giving rise to the next generation of an electric car, eVTOL, skyscraper, or even Mars Rover.The possibility to harness the power of quantum computers is endless, and we at BQP thrive on pushing the boundaries of quantum computing technologies to serve our clients. We have made it our mission to bring these possibilities into the hands of every person - from a researcher to a scientist, from a professor to a student. Our name, BosonQ Psi, pays tribute to the great Indian physicist Dr. Satyendra Nath Bose, after whose name the elementary particle in quantum mechanics, Boson, was named and further incorporates the fundamental quantity that describes the state of the quantum particle - Psi, thus symbolizing the company's fundamental goal to contribute in India's goal to be the leader in the Quantum realm and also become a global leader in Quantum paradigm shift in coming years.
  • Willow Wealth — Willow Wealth is an alternative investment platform focused on generating income streams for investors. Get exclusive access to private market investments.
  • Hubble Network — Connect a Bluetooth device to a global satellite network, delivering affordable, low-power tracking and monitoring for diverse industrial and commercial applications.
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Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 17 investments in United States Medical Device startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 1792
  • Round size: Seed $1.5M–$10M; Series A $5.5M–$37M; Series B $11M–$79M
  • Lead/follow: 7% lead, 93% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Verishop — Shop designer clothing, shoes, bags and accessories from top Italian boutiques. Discover the latest luxury fashion at competitive prices with global shipping.
  • Civis Analytics — Data solutions that deliver messages to your audiences and turn your data into successful campaigns. Make smarter, faster decisions that drive real results.
  • RAAAM Memory Technologies Ltd. — RAAAM provides a unique on-chip memory technology that offers the highest-density embedded memory solution in any standard CMOS process.RAAAM develops a high-density memory technology that allows for up to 50% higher on-chip memory density with no cost, complexity, or performance-penalty.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

Browse database — It's Free!
Arboretum Ventures
VC Fund · Ann Arbor, Michigan, United States · 16 investments in United States Medical Device startups

For over 20 years we have been a successful healthcare venture capital firm rooted in the Midwest. Check out our portfolio companies.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 114
  • Round size: Series A $4.4M–$27M; Series B $5M–$55M; Series C $10M–$80M
  • Lead/follow: 45% lead, 55% follow
  • Last fund: May invest from a new fund soon — raised $250M in 2019

Portfolio highlights

  • Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
  • Boomerang Medical — Boomerang Medical is a bioelectronic medicine company targeting autoimmune diseases.
  • Pharaoh Neuro — Pharaoh Neuro develops a neurapheresis cerebrospinal fluid management system for neurological patients.
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North Coast Ventures
VC Fund · Cleveland, Ohio, United States · 16 investments in United States Medical Device startups

North Coast Ventures (formerly North Coast Angel Fund) is comprised of four contributed capital funds with a focus on early-stage technology investments. Our membership consists of a number of Ohio's leading investors, entrepreneurs, and business leaders who are dedicated to accelerating early-stage ventures.North Coast Ventures members playan active role by generating deal flow, serving on due diligence teams, working with portfolio companies, or serving on the Investment Screening and Executive Committees. Through this involvement, our goal is to provide a supportive environment for our portfolio companies and ultimately enhance the performance of our Fund.Northeast Ohio has a long tradition of active and successful angel investing, but until recently, the success of this crucial form of funding has hinged on the efforts of a relatively small number of individual investors. As the region’s first professionally managed angel fund, North Coast Angel Fund works to improve the early-stage funding environment for both entrepreneurs and investors.

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Investment focus

  • Industry: Health Care, Software, Medical Device
  • Stage:Series A, Seed
  • Geography: United States

Investor stats

  • Total investments: 100
  • Round size: Seed $350k–$5.5M; Series A $1.2M–$10M
  • Lead/follow: 21% lead, 79% follow
  • Last fund: May invest from a new fund soon — last raise in 2013

Portfolio highlights

  • Primum
  • FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
  • InnerActiv — InnerActiv is a cybersecurity software company that protects organizations from insider threats, fraud, and data loss at the endpoint. Built with an AI-driven, behavior-based approach, InnerActiv delivers real-time visibility into how users interact with sensitive data, systems, and devices—detecting risky activity such as data grazing, policytesting, and low-and-slow reconnaissance before it leads to a breach. The platform’s lightweight, encrypted agents and endpoint-first design provide proactive protection, faster response, and seamless integration with existing security stacks.
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Wavemaker 360
VC Fund · Pasadena, California, United States · 16 investments in United States Medical Device startups

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

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Investment focus

  • Industry: Health Care, Medical, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 85
  • Round size: Seed $750k–$6M; Series A $1.9M–$16M; Series B $20M–$30M
  • Lead/follow: 12% lead, 88% follow
  • Last fund: Likely still investing — raised $64M in 2022

Portfolio highlights

  • Tombot — We create robotic animals that transform the daily lives of individuals, families, and communities facing health adversities. Reserve your Tombot Puppy today for FREE
  • Lium — Lium provides a platform that structures technical datasets and makes them accessible through natural language, enabling teams to analyze, understand.
  • ChemT Biotechnology — The goal of ChemT Biotechnology is to increase patient access to the most cutting-edge biologics, beginning with the urgent issues in manufacturing and research and development.
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Maine Angels
VC Fund · Portland, Maine, United States · 15 investments in United States Medical Device startups

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series A
  • Geography: United States

Investor stats

  • Total investments: 129
  • Round size: Seed $25k–$1.2M; Series A $662k–$5.9M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Waku — Deliciously replenishing herbal tea with prebiotic powers and 0g of added sugar. Experience Sunrise on the Inside.
  • HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
  • Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.
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Texas HALO Fund
VC Fund · Houston, Texas, United States · 15 investments in United States Medical Device startups

Early Stage Venture Investments

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Investment focus

  • Industry: Health Care, Medical Device, Software
  • Stage:Seed, Convertible Note, Series A
  • Geography: United States, Canada, Hungary

Investor stats

  • Total investments: 92
  • Round size: Seed $105k–$3M; Series A $3M–$10M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — raised $175k in 2021

Portfolio highlights

  • Flourish Care — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
  • Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
  • Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.
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MB Venture Partners
VC Fund · Memphis, Tennessee, United States · 15 investments in United States Medical Device startups

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Series B, Series C
  • Geography: United States, Israel

Investor stats

  • Total investments: 90
  • Round size: Seed $50k–$700k; Series B $1.3M–$18M; Series C $5M–$28M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — raised $22M in 2011

Portfolio highlights

  • Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
  • SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
  • Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.
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Oxford Finance LLC
VC Fund · Alexandria, Virginia, United States · 15 investments in United States Medical Device startups, 6 in the past 12 months

Providing Flexible and Creative Financial Solutions to Middle Market Companies.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Debt Financing, Post-IPO Debt, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 124
  • Round size: Series B $39M–$76M; Post-IPO Debt $15M–$150M; Debt Financing $7.5M–$96M
  • Lead/follow: 51% lead, 49% follow

Portfolio highlights

  • Sokin — Sokin is a leading financial service provider that enables global payments for both consumers and businesses. Sokin believes in giving you the power to make payments and transfer money as many times as you want per month! Whether it’s sending money back home or transfers to friends or even settling with businesses using Sokin, our innovativeprocess makes the task quick and easy.Sokin delivers global payments for a fixed fee, is commission and hassle free!Transferring money internationally is complicated and expensive. Sometimes there is a lack of transparency in the fees you pay. With our transparent fixed monthly costs, for businesses and consumers, there are no hidden charges. You will not have to spend hours researching the best rates!Our cost effective solution is simple to understand: One Monthly Fee. This will to allow you to make payments in over 200 countries and the ability to exchange money in over 150 countries in over 35 different currencies. Sokin can also transfer any currency into any bank account in China within 2 hours excluding weekends and Chinese bank holidays.To find out more about the only payment provider to provide global payments for a fixed fee, commission free and hassle free – download our app and sign up to ensure you don’t miss out on key messages!
  • Inhibrx — Inhibrx is a clinical-stage biotechnology company focused on developing a broad pipeline of novel biologic therapeutic candidates. Inhibrx utilizes diverse methods of protein engineering to address the specific requirements of complex target and disease biology, including its proprietary sdAb platform. The Inhibrx pipeline is focused on oncology,orphan diseases and infectious diseases. Inhibrx has collaborations with Celgene and bluebird bio and has received awards from several granting agencies, including NIH, NIAID and CARB-X.
  • Vortexa — State of the art energy analytics that paints a global picture of cargo flows. Identify energy market opportunities before the competition with Vortexa.
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 15 investments in United States Medical Device startups

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 259
  • Round size: Seed $300k–$5.3M; Series A $2.4M–$25M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — raised $50M in 2023

Portfolio highlights

  • 1touch.io — By continuously analyzing traffic and repository stores connected to your network, our network-based solution can detect all elements on the network that are storing, processing, and sharing personal data, both internally and externally. Whether structured or unstructured data, data in motion or at rest, and even data that is unknown to you,1touch.io can track it for you.
  • Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
  • LegiTime Technologies — Miami Embracing New Technology and Safety
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Good Growth Capital
VC Fund · Charleston, South Carolina, United States · 14 investments in United States Medical Device startups

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, France, Israel

Investor stats

  • Total investments: 115
  • Round size: Seed $505k–$12M; Series A $4.2M–$20M; Convertible Note $25k–$300k
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — raised $100M in 2023

Portfolio highlights

  • Obsidio — Obsidio™ Conformable Embolic with aqueous gel technology is a 510(k) cleared device, the first of its kind to have a specific on-label indication for peripheral use in the U.S.
  • NALA Membranes — NALA Systems is a cleantech startup company located in the heart of Research Traingle Park in Durham, NC. The NALA team is dedicated helping to change the global water crisis by producing a new chlorine tolerant membrane for reverse osmosis. Click to learn more.
  • Osteoboost — Bone Health Technologies specializes in developing medical devices designed for low bone mass. Its solution is a gentle mechanical stimulation that mimics weight-bearing exercise, providing an effective non-drug intervention. It offers the OsteoBoost device that relies on safe, natural, and effective whole-body vibration technology usingvibrational energy to turn stem cells into the bone using the same mechanisms as physical exercise. The company was founded in 2018 and is headquartered in San Francisco, California.
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Life Science Angels
VC Fund · Sunnyvale, California, United States · 14 investments in United States Medical Device startups

Life Science Angels, Inc. (LSA) is the premier angel investment group focused solely on healthcare investing, including medical devices, diagnostics, pharmaceuticals, biotechnology, and digital health.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A
  • Geography: United States, Israel, The Netherlands

Investor stats

  • Total investments: 88
  • Round size: Seed $1M–$4M; Series A $1.3M–$20M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • ATDev — ATDev provides assistive technology and medical device solutions.
  • Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
  • Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.
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Golden Seeds
VC Fund · New York, New York, United States · 14 investments in United States Medical Device startups

Golden Seeds is a seed-stage investment firm with a focus on women leaders. Their investment thesis rests on the extensive research that concludes that gender-diverse teams produce a better return on equity. By seeking companies where women hold leadership positions and own substantial equity, they are funding companies that are likely to havediverse perspectives that will contribute to success.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada

Investor stats

  • Total investments: 147
  • Round size: Seed $740k–$5.6M; Series A $1.2M–$10M; Series B $1.8M–$20M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • RenovoRx — RenovoRx is a developing innovative solutions for targeted delivery of fluids, including diagnostic and therapeutic agents, to selected sites in the peripheral vascular system. RenovoRx received FDA clearance for the RenovoCath™ RC120 and is currently introducing this innovative technology to the clinical market.RenovoRx has a motivatedManagement Team with broad experience and an exciting vision for the future of targeted delivery. The company also has a broad Advisory Board of interventional radiologists, surgical oncologists and gastroenterologists that guide the company's clinical development strategies. RenovoRx is backed by a strong Board of Directors committed to long-term, continuous support of the company, whose members provide critical expertise in the medical and biotechnology industry and the visionary thinking to succeed.
  • ColorModules — ColorModules is an early stage start-up which has created a patent-pending search technology that recommends products to consumers based on "visual" characteristics and preferences, such as color. ColorModules sets out to alleviate the common shopping frustration of searching dozens or hundreds of items to find the right product.Currently, ColorModules focuses on the visually-driven beauty, fashion, and home décor industries.Its first website, PlumPerfect.com, is for beauty shoppers. Users can take and upload a photo, and the service recommends for them colors and products.
  • Style for Hire — Style for Hire is a national network of trained and certified personal stylists who bring affordable in-home wardrobe advice and shopping assistance to customers. Celebrity stylist Stacy London, from TLC's What Not to Wear, is co-founder, spokesperson, and Stylist-in-Chief.
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Boston Harbor Angels
VC Fund · Boston, Massachusetts, United States · 14 investments in United States Medical Device startups

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical Device
  • Stage:Angel, Seed, Series A
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 107
  • Round size: Seed $100k–$2.9M; Angel $500k–$1.6M; Series A $662k–$6M
  • Lead/follow: 8% lead, 92% follow

Portfolio highlights

  • Gelmedix — Gelmedix is a developer of a biomaterial platform to improve drug delivery for complicated ophthalmic treatment. The company's platform offers a single non-invasive gel patch that can be used as a drug-eluting sealant with tissue adhesion, tunable drug elution, and biocompatibility properties, thereby enabling healthcare providers to reducethe usage of drops which cause inconvenience to patients.
  • Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
  • Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.
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Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund · Philadelphia, Pennsylvania, United States · 13 investments in United States Medical Device startups

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

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Investment focus

  • Industry: Health Care, Software, Information Technology
  • Stage:Seed, Grant, Debt Financing
  • Geography: United States

Investor stats

  • Total investments: 139
  • Round size: Seed $100k–$2.2M; Grant $5k–$100k; Debt Financing $975k–$975k
  • Lead/follow: 38% lead, 62% follow

Portfolio highlights

  • CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
  • Aigensei — Aigensei.ai develops artificial intelligence software and infrastructure tools that support the creation, deployment, and management of AI applications. Its work includes systems for workflow automation, model integration, and operational use of AI across different computing environments and application domains.
  • LoanStar Technologies — LoanStar works with lenders to diversify their consumer loan origination strategies. Providing program consulting, market-leading software, and merchant aggregation, LoanStar helps lenders of every size leverage the power of their local brand.LoanStar has developed the MerchantLinQ platform that enables lenders of all sizes to deploy instantpoint-of-sale finance through their local merchants.
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Versant Ventures
VC Fund · Menlo Park, California, United States · 13 investments in United States Medical Device startups

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 287
  • Round size: Series A $4.7M–$84M; Series B $10M–$105M; Series C $12M–$108M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Graphite Bio — Graphite Bio is a next-generation gene editing company focused on therapies that harness targeted gene integration to treat or cure serious diseases
  • Lycia Therapeutics — Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras. The company was founded by Carolyn R. Bertozzi in 2019 and is based in San Diego, California, USA.
  • Nested Therapeutics — Nested Therapeutics is a Cambridge-based VC-backed stealth biotech company. The company's focus is on finding and creating new precision oncology small-molecule drugs targeted toward cancer genes. Nested Therapeutics was established in 2021 in Cambridge, Massachusetts.
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Catalyst Health Ventures
VC Fund · Braintree, Massachusetts, United States · 13 investments in United States Medical Device startups

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States

Investor stats

  • Total investments: 47
  • Round size: Series A $1.4M–$19M; Series B $2.3M–$33M; Series C $1.3M–$85M
  • Lead/follow: 51% lead, 49% follow
  • Last fund: May invest from a new fund soon — raised $75M in 2019

Portfolio highlights

  • Lena Health — Lena is a virtual health assistant that takes care of all tasks to stay on top of the care plan, so you can sit back and focus on the things that matter to you.
  • Rejoni — Rejoni uses bio-materials to develop medical devices that improve the outcome of minimally invasive and gynecological surgical procedures.
  • Esperto Medical — Esperto Medical is an Irvine, CA-based medical device company developing next-generation wearable diagnostics that enable hospital-based and remote patient monitoring with unprecedented ease and accuracy. Its unique resonance sonomanometry technology uses acoustic stimulation to directly and noninvasively measure continuous blood pressure withoutcalibration.
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Right Side Capital Management
VC Fund · San Francisco, California, United States · 13 investments in United States Medical Device startups

Systematic Pre-Seed Startup Capital

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Investment focus

  • Industry: Software, SaaS, Health Care
  • Stage:Seed, Pre-Seed, Convertible Note
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 1143
  • Round size: Seed $20k–$2M; Pre-Seed $50k–$448k; Convertible Note $50k–$500k
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Cohley — Cohley is a content marketing platform focusing on user generated content, visual asset creation, and text review generation. Streamline your content generation today!
  • Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
  • Vector ML Analytics — Vector ML is a financial analytics tool used by executives and analysts at banks and lending institutions to increase return, lower risk, and manage liquidity. It combines treasury, credit risk, FP&A, and capital market features in a single application using AI and automation, allowing for a 360-degree view of the balance sheet. Visit us atwww.vectormla.com
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 13 investments in United States Medical Device startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1160
  • Round size: Seed $2M–$25M; Series A $5.5M–$47M; Series B $10M–$100M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely still investing — raised $557M in 2022

Portfolio highlights

  • Wattpad — Wattpad is a digital entertainment company providing an online social storytelling platform for original stories.The company utilizes the power of community and technology to enable the creation and distribution of content across a variety of formats. Its flagship app, Wattpad, is home to a community of more than 65 million people who spend over20 billion minutes a month engaged in original stories. Tap by Wattpad, the company’s second storytelling product, offers short, chat-based stories in over a dozen languages. Wattpad Studios co-produces stories for film, television, digital, and print, together with industry partners. Wattpad Brand Solutions offers a full suite of advertising products to help brands build deep engagement with Millennial and Gen Z consumers.It was established by Allen Lau and Ivan Yuen in Toronto, Ontario, Canada in 2006.
  • Breeze — Cargo insurance reinvented.
  • Shoes of Prey — Shoes of Prey creates bespoke, hand-made women's shoes designed by the customer, and delivers them to anywhere in the world.Shoes of Prey has grown rapidly over 5 years and has won a number of awards including Online Retailer of the Year and Store Design of the Year at the World Retail Awards in Paris 2013.Founded in 2009, the company isheadquartered in Santa Monica, California, United States.
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Sand Hill Angels
VC Fund · Mountain View, California, United States · 13 investments in United States Medical Device startups

For over two decades, Sand Hill Angels has worked openly and collaboratively with venture capital funds, other angel organizations, and the Bay Area ecosystem that fosters the growth of technology startups.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Japan

Investor stats

  • Total investments: 231
  • Round size: Seed $1M–$6.5M; Series A $1.4M–$18M; Series B $8.5M–$100M
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • Lincode — The #1 business challenge that manufacturers identify is quality management. As new manufactured products continue to enter the market and consumer expectations shift faster than ever, factories are looking to improve their quality systems while scaling operations and cutting costs. At Lincode, we enable manufacturers to improve the speed, accuracy, and data tracking capabilities of their quality inspection systems at scale.
  • Madison Reed — Madison Reed is transforming at home hair color with ammonia free hair dye that results in multi-dimensional color that looks beautiful, healthy and natural.
  • Clean Power Finance — Clean Power Finance (CPF) is building an online business-to-business marketplace to drive the mass-market adoption of solar. The company connects providers of capital who are committed to investing in residential solar with qualified solar marketers, installers and distributors who need residential solar finance products to differentiate and growtheir businesses. CPF raises 100 percent third-party‐owned project finance funds from institutional investors such as Morgan Stanley and Google, working with the investors to structure and launch the funds with managed risk and return profiles. CPF then markets the funds as solar leases and power purchase agreements (PPAs) to qualified solar professionals, including Paramount Solar and Real Goods Solar (Nasdaq: RSOL), through its licensed online solar sales platform, CPF Tools. CPF Tools is software-as-a-service that simplifies complex sales, quoting, proposal and finance processes and minimizes the “soft costs” of selling solar.CPF’s fund investors earn favorable returns on stable investments on the resulting portfolios of residential distributed generation projects. The company’s solar professional partners gain access to solar leases and power purchase agreements (PPAs) that they can brand and sell to homeowners who want the benefits of solar without the cost and hassle of owning and maintaining a system.CPF manages approximately half a billion dollars of capacity on behalf of fund investors, and supports more than 100 solar professional customers who currently use the CPF Market to sell residential solar finance products to homeowners in CA, CO, HI, MA and NJ. Thousands of solar professionals in all 50 states have extensively used CPF Tools to quote and design solar systems.
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Keiretsu Forum
VC Fund · San Francisco, California, United States · 12 investments in United States Medical Device startups

Keiretsu Forum is a global angel investor network with more than 2,500 accredited investor members throughout 47 chapters on 3 continents.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series A
  • Geography: United States, India, Turkey

Investor stats

  • Total investments: 220
  • Round size: Seed $102k–$3.6M; Series A $600k–$8.6M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2015

Portfolio highlights

  • Bliss — Bliss is an AI-powered online therapy platform that provides online mental health and wellness services to make mental health support more accessible, affordable, and culturally sensitive. The company connects individuals with licensed therapists and mental health professionals for video, audio, and messaging-based counseling sessions. Its platformincludes therapist matching tools, secure communication systems, appointment scheduling, and multilingual support designed for users seeking culturally aligned care. Bliss supports mental health needs related to anxiety, depression, trauma, relationships, stress management, and personal development through remote therapy services. The company also offers mental wellness programs for businesses, providing employee support resources, coaching access, and digital mental health services for distributed teams. Its services are designed to make therapy and emotional support accessible through online and mobile-based interactions.
  • BatteryPool — BatteryPool offers battery charging solutions for EV fleets and commercial vehicles.
  • Apriority Financial — Apriority Financial is a debt optimization platform that manages and optimizes employee personal debt.
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Wisconsin Investment Partners
VC Fund · Madison, Wisconsin, United States · 12 investments in United States Medical Device startups

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 115
  • Round size: Seed $400k–$3M; Series A $1.1M–$7M
  • Lead/follow: 15% lead, 85% follow

Portfolio highlights

  • DropCap — DropCap is a tech-enabled rights agency (dropcap.com) and a global rights marketplace used by rights agents and acquisitions editors around the world to find great books (dropcapmarketplace.com). Our mission is to provide independent authors and publishers access to rights licensing opportunities and help indie books go global through foreignrights, audio, and film rights licensing.
  • Cylerity — Transform healthcare receivables into real-time capital. Cylerity unlocks cash flow, clarity, and control from claims data. See how it works.
  • Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 12 investments in United States Medical Device startups, 6 in the past 12 months

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 197
  • Round size: Seed $192k–$4M; Series A $1.2M–$18M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: May invest from a new fund soon — raised $20M in 2021

Portfolio highlights

  • FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
  • InnerActiv — InnerActiv is a cybersecurity software company that protects organizations from insider threats, fraud, and data loss at the endpoint. Built with an AI-driven, behavior-based approach, InnerActiv delivers real-time visibility into how users interact with sensitive data, systems, and devices—detecting risky activity such as data grazing, policytesting, and low-and-slow reconnaissance before it leads to a breach. The platform’s lightweight, encrypted agents and endpoint-first design provide proactive protection, faster response, and seamless integration with existing security stacks.
  • Niobium Microsystems — The encrypted cloud has arrived.
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Boutique Venture Partners
VC Fund · Palo Alto, California, United States · 12 investments in United States Medical Device startups

Boutique Venture Partners specializes in early-stage investments in healthcare and life sciences

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Investment focus

  • Industry: Health Care, Medical, Biotechnology
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 37
  • Round size: Seed $2.5M–$5.7M; Series A $4M–$31M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • QMENTA — Our industry-leading neuroimaging cloud-based software works with advanced AI-powered tools to empower researchers, radiologists, and clinical trials.
  • miRecule — MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics. It features a genomic-based drug development platform that integrates genomic sequencing, expression, and prognostic data from cancer patients. The company was founded in 2016 and headquartered in Gaithersburg, United States.
  • Surge — SurgeCare leverages immune profiling and AI to reveal early immune signatures and drive better decisions in surgery, trauma, infection, and beyond.
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Everywhere Ventures
VC Fund · New York, New York, United States · 12 investments in United States Medical Device startups

Everywhere Ventures is a global pre-seed venture capital fund for founders, by founders. Click to read Everywhere VC, by Everywhere Ventures, a Substack publication with tens of thousands of subscribers.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Pre-Seed, Seed, Series A
  • Geography: United States, Australia, India

Investor stats

  • Total investments: 714
  • Round size: Seed $1.5M–$7.2M; Pre-Seed $550k–$2.7M; Series A $10M–$60M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Donna — Meet Donna, the AI assistant built for field sales teams. Save time, cut admin, and close more deals with less effort.
  • Suma Wealth — SUMA is a revolutionary financial wellness company with the mission to engage, educate, and empower the Latinx community via a holistic approach of Digital Media, Experiences, and FinTech. By creating culturally relevant content, virtual experiences, and providing financial tools that demystify and reimagine financial wellness throughentertainment, we aim to become the trusted source to help Latinos own their economic power, overcome financial challenges, and better prepare for a more prosperous future.
  • Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
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U.S. Venture Partners
VC Fund · Menlo Park, California, United States · 12 investments in United States Medical Device startups, 14 in the past 12 months

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series C, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 413
  • Round size: Series A $5M–$42M; Series B $7M–$51M; Series C $6M–$67M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Nervonik — Explore Nervonik neuromodulation devices that are working to redefine peripheral nerve stimulation with advanced technology for high motion.
  • Cagent Vascular — Cagent Vascular Inc. is a developer of next generation angioplasty balloons using Serration Technology for the treatment of cardiovascular disease.
  • Maneva — Maneva Copilot AI is able to interpret, summarize, and combine the diverse landscape of data that exists throughout your production facility, and deliver the appropriate content to the question provided at all levels of roles, whether it is operational supervisors, quality managers, and management, process engineers, or maintenance leads
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Horizon Technology Finance
VC Fund · Farmington, Connecticut, United States · 12 investments in United States Medical Device startups, 6 in the past 12 months

Horizon is a venture lending platform that offers structured debt products to life science and technology companies. Its team of investment and operations professionals has been providing debt capital to some of the most exciting companies for decades. The members of the Horizon team have, collectively, originated and invested more than $5 billionin venture loans to thousands of companies.The company was founded in 2003 and is headquartered in Farmington, Connecticut.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Debt Financing, Post-IPO Debt
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 109
  • Round size: Post-IPO Debt $10M–$40M; Debt Financing $5M–$30M
  • Lead/follow: 71% lead, 29% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Ossio — OSSIO is an orthopedic fixation company committed to transforming the orthopedic experience for patients, physicians, and payors. Their vision is to provide the first credible replacement to metal implants in the $10B+ orthopedic fixation market (screws, pins, plates) with an Intelligent Bone Regeneration Technology. OSSIOfiber represents abreakthrough material platform for orthopedic and podiatric surgeons who seek a more biologically friendly way to restore patient stability and mobility with nothing permanent left behind.Founded in 2014, OSSIO began as the culmination of years of biomechanical research and a vision for the possibility of better bone healing. The technological basis of OSSIOfiber™ was developed and would lay the groundwork for ushering in a new breakthrough category of non-permanent fixation, “Bio-Integratives” hardware that has both desired strength AND bio-friendliness. Hardware that has the mechanical strength for easy insertion and secure fixation, while enabling the body to regrow bone, incorporating and replacing the implant (without the adverse inflammation and weakness often seen in “bio-resorbables and other “bio-composites”), has remained elusive to the industry until now.
  • Stellar Cyber — Stellar Cyber: Automation-Driven, Open & Unified SecOps Platform with AI SIEM, NDR, Open XDR, and Multi-Layer AI.
  • Hyperfine — Hyperfine makes MRI accessible to every patient regardless of income or resources.
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Houston Angel Network
VC Fund · Houston, Texas, United States · 11 investments in United States Medical Device startups

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

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Investment focus

  • Industry: Health Care, Software, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 133
  • Round size: Seed $25k–$1.8M; Series A $240k–$5M
  • Lead/follow: 8% lead, 92% follow

Portfolio highlights

  • ITeam — iTeam is transforming the way information technology (IT) and audio/video (A/V) installation services are packaged, sold and delivered through a new approach called Service-as-a-Product™ (SaaP™).
  • Monster Mosquito — Monster Mosquito focuses on providing all-natural mosquito sentry repellent systems for its clients. The company also develops a biodegradable compound insecticide to exterminate biting insects.Monster Mosquito uses mosquito mist systems, which contains pyrethrum, a natural mosquito killer made from chrysanthemums. The company was founded in 2002by Kemper Modlin and Leo Niekerk.It is based in Spring, Texas.
  • Quarri Technologies — Quarri is a leading provider of on demand web browser information security solutions that secure information and content at the endpoint. Their products give enterprises the ability to extend security controls temporarily to web browsers accessing their web applications, providing information protection and data leakage prevention wherever yourusers are.
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Kleiner Perkins
VC Fund · Menlo Park, California, United States · 11 investments in United States Medical Device startups, 34 in the past 12 months

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 1031
  • Lead/follow: no public data

Portfolio highlights

  • Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
  • Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
  • Hippocratic AI — The First Safety Focused LLM for Healthcare
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Hatteras Venture Partners
VC Fund · Durham, North Carolina, United States · 11 investments in United States Medical Device startups

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada

Investor stats

  • Total investments: 131
  • Round size: Series A $5.2M–$50M; Series B $5M–$90M; Series C $8M–$88M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Ribometrix — The Next Frontier of Drug Discovery
  • G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.
  • Viamet Pharmaceuticals — Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allowsthem to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.
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Asset Management Ventures (AMV)
VC Fund · Palo Alto, California, United States · 11 investments in United States Medical Device startups

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Seed, Series B
  • Geography: United States, Cyprus, Ireland

Investor stats

  • Total investments: 145
  • Round size: Seed $500k–$6M; Series A $2.4M–$21M; Series B $5M–$35M
  • Lead/follow: 22% lead, 78% follow
  • Last fund: May invest from a new fund soon — raised $150M in 2020

Portfolio highlights

  • SeeQC — SEEQC is developing the first digital quantum computing platform for businesses. SEEQC combines classical & quantum technologies to address the efficiency, stability & cost issues endemic to quantum computing.
  • Outcomes4Me — Outcomes4Me is empowering cancer patients globally with treatment options, medical records, and clinical trials all in one app.
  • Autonomize AI — AI That Runs Healthcare. For the Humans Who Make It Work. AI-Native Infrastructure: Rewiring Healthcare Operations for the Next Era.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 11 investments in United States Medical Device startups

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 163
  • Round size: Series A $19M–$110M; Series B $11M–$190M; Series C $14M–$108M
  • Lead/follow: 45% lead, 55% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
  • Jounce Therapeutics — Concentra is a biosciences company.
  • Terremoto Biosciences — By unleashing the power of covalent chemistry, we can deliver superior small molecule medicines with enhanced therapeutic benefit.
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St. Louis Arch Angels
VC Fund · St Louis, Missouri, United States · 11 investments in United States Medical Device startups

The St. Louis Arch Angels is a network of accredited investors who fund early-stage businesses across the St. Louis region.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical Device
  • Stage:Seed, Series A
  • Geography: United States, Argentina

Investor stats

  • Total investments: 76
  • Round size: Seed $100k–$3.3M; Series A $1.5M–$8.5M
  • Lead/follow: 43% lead, 57% follow

Portfolio highlights

  • Peptyde Bio — Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.
  • SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
  • Maximum Fidelity Surgical Simulations — The most realistic surgical and trauma simulations for surgeons, forward field operators, medics and medical device development.
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TCA Venture Group
VC Fund · Newport Beach, California, United States · 11 investments in United States Medical Device startups

TCA Venture Group is the largest angel investor group in the United States, possessing more than 300 members in five networks in Los Angeles, Orange County, San Diego, Central Coast, and the Inland Empire. Its members provide funding and guidance to more early-stage, high-growth companies in Southern California than any other investment group.Members invest in companies in a wide range of industries, including the life sciences, biotech, IT, services, retail, Internet, financial, software, media, consumer products, and tech startups. TCA as a whole gives companies more than just capital; they also provide counsel, mentoring, and access to an extensive network of potential investors, customers, strategic partners, and management talent. Tech Coast Angels has been ranked by CB Insights to be among the Top 20 Angel Groups in the US; TCA was also ranked as #1 for Network Centrality, meaning we have more connections than anyone! If you are in the game-changing business, we are here to help.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 234
  • Round size: Seed $690k–$4M; Convertible Note $50k–$7M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — last raise in 2015

Portfolio highlights

  • Elemeno Health — Elemeno Health is an intuitive, cloud-based app, customized to specific needs of your hospital or unit. Streamline training and communication, drive best practices, and empower your staff with just-in-time access to critical information.
  • NovaSignal — NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system. Robotic System combines non-invasive ultrasound, robotics, and artificial intelligence to assess real-time cerebral blood flow.
  • MatriSys Bioscience — MatriSys sees commercialization paths for its intellectual property in topical dermatology therapeutics, cosmetics, and skin care. The company’s lead live biologic therapeutic is currently in Phase I/II clinical trials targeting atopic dermatitis (commonly referred to as AD or eczema) patients.
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Mayo Clinic
VC Fund · Rochester, Minnesota, United States · 11 investments in United States Medical Device startups, 11 in the past 12 months

Mayo Clinic, a not-for-profit medical group practice, provides medical care, research, and education services. It offers medical care services in various specialties, including diabetes and endocrinology, gastroenterology, gynecology, cancer, neurology and neurosurgery, orthopedics, pulmonology, rheumatology, nephrology, urology, and cardiology andheart surgery.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 110
  • Round size: Seed $100k–$6M; Series A $3.5M–$40M; Series B $8M–$100M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • ViewsML — Explore cutting-edge AI solutions for cancer treatment, diagnosis, and research. Discover how clinical labs leverage artificial intelligence for precise cancer detection and diagnosis.
  • SyntaxBio — SyntaxBio develops CRISPR/Cas9-based, genetic programming platform that converts cells into biological computers using DNA-based instructions that read like lines of code. SyntaxBio's platform can program cells without the need for consistent external intervention.
  • Techcyte — Techcyte is an AI software platform for clinical pathology that leverages machine learning for quicker, more efficient diagnoses for laboratories and patients.
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The Vertical Group
VC Fund · Basking Ridge, New Jersey, United States · 10 investments in United States Medical Device startups

The Vertical Group is a New Jersey-based venture capital firm focused on the fields of medical technology and biotechnology.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series B, Series C
  • Geography: United States, Israel

Investor stats

  • Total investments: 70
  • Round size: Series B $5M–$60M; Series C $1.5M–$77M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2006

Portfolio highlights

  • Luminopia — Luminopia is the first FDA-approved binocular therapy for amblyopia.
  • Mobia Medical — MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas.
  • Route 92 Medical — The official website for Route 92 Medical.
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Three Arch Partners
VC Fund · Portola Valley, California, United States · 10 investments in United States Medical Device startups

Three Arch Partners was formed in 1993 to provide young companies with access to relevant clinical and business resources, as well as capital. Three Arch has helped create, build and fund more than 100 important new healthcare companies. These companies have often become the clinical and market leaders in their respective fields, and have generatedstrong returns. The fund focuses on opportunities in medical devices and healthcare services, and less frequently in biotechnology.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Series B, Series C
  • Geography: United States, Belgium

Investor stats

  • Total investments: 75
  • Lead/follow: no public data

Portfolio highlights

  • Nevro — Nevro is a global medical device company focused on providing innovative products that improve the quality of life of patients suffering from debilitating chronic pain. Nevro has developed and commercialized the Senza spinal cord stimulation (SCS) system, an evidence-based neuromodulation platform for the treatment of chronic pain. The Senza systemis the only SCS system that delivers Nevro's proprietary HF10 therapy. Senza, HF10, Nevro and the Nevro logo are trademarks of Nevro.
  • Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
  • Access Closure — Access Closure, Inc., a medical device company, provides access site management products to address the complex challenge of vascular closure during interventional and diagnostic procedures. The company's products include Mynx delivery system, a vascular closure device that seals the arteriotomy using a water-soluble and extravascular sealant,which expands in the tissue tract by absorbing blood and subcutaneous fluids. Access Closure, Inc. was founded in 2002 and is based in Mountain View, California.
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Emergent Medical Partners
VC Fund · Portola Valley, California, United States · 10 investments in United States Medical Device startups

Providing funding and expertise for early-stage medical device companies.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series C, Series A, Series B
  • Geography: United States, France

Investor stats

  • Total investments: 38
  • Lead/follow: no public data

Portfolio highlights

  • Shape Memory Medical — Smart polymer. Smart embolization. Smart choice. Reshaping your view of clinical success through the science of smart polymer.
  • Standard Bariatrics — Cincinnati-based surgical procedure company focused on innovative development, commercialization of medical devices for treatment of obesity, gastrectomy.
  • Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.
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Oxford Bioscience Partners
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Medical Device startups

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Investment focus

  • Industry: Health Care, Biotechnology, Pharmaceutical
  • Stage:Series B, Series C, Series A
  • Geography: United States, Germany, Switzerland

Investor stats

  • Total investments: 109
  • Round size: Series A $3.5M–$26M; Series B $10M–$48M; Series C $5.6M–$50M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: May invest from a new fund soon — raised $66M in 2011

Portfolio highlights

  • Paperspace — Ceres, Inc. (Ceres) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks. The Company’s large-scale commercial products are sweet sorghum varieties that can be used as a drop-in feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills. Its products include sweet sorghum, high biomasssorghum, switchgrass, miscanthus and row crops. Its energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Baseload utility scale electric power can also be generated from the biomass feedstocks grown from its seeds. Ceres has sold switchgrass and high biomass sorghum seeds in the United States under its Blade Energy Crops (Blade) brand. In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda.
  • CardioFocus — CardioFocus is a biotechnology company that focuses on the advancement of ablation treatments for cardiac disorders. The company specializes in providing electrophysiologists with innovative and effective tools that bring new levels of precision and control to the treatment of atrial fibrillation that focuses on developing, manufacturing, andinvestigating disposable fiber optic catheters for the visualization of the cardiac anatomy and the treatment of cardiac arrhythmias.CardioFocus was founded in 1990 and is headquartered in Marlborough, Massachusetts.
  • Yolia Health — Yolia Health developed The True Vision Treatment or TVT, the 'Invisalign' for the eyes. A non-invasive treatment to correct vision problems like presbyopia without surgery. TVT is self-administered by the patient in his or her own home. It employs a combination of customized contact lenses (TVT Contacts) and specially formulatedeye drops (TVT Eye Drops). After only 5 days of treatment with TVT patients are able to stop using the TVT Contacts, TVT Eye Drops and their reading glasses for up to 12 months at a time before re-treatment with TVT is needed. What is even greater than correcting for presbyopia non-invasively, is correcting both eyes without compromising any distance vision. On the contrary, Yolia's treatment improves both near and distance vision, a unique feature no single other alternative can provide. ** Looking for sophisticated investors and key industry partners.
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Morgenthaler Ventures
VC Fund · Menlo Park, California, United States · 10 investments in United States Medical Device startups

Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series B, Series A
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 225
  • Lead/follow: no public data

Portfolio highlights

  • Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
  • SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
  • Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.
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Rockies Venture Club
VC Fund · Denver, Colorado, United States · 10 investments in United States Medical Device startups

Connecting Entrepreneurs and Investors Since 1985.

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Investment focus

  • Industry: Software, Health Care, Medical Device
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 118
  • Round size: Seed $250k–$2.3M; Series A $1.2M–$7M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: May invest from a new fund soon — last raise in 2016

Portfolio highlights

  • MyUTI — Discover fast, reliable, easy at home testing with MyUTI. Our proven PCR testing for UTIs, BV and STIs delivers accurate results, test from the comfort of your home. Get care from home with our discreet and direct UTI lab test service.
  • Pure Blue Tech Inc. — Pure Blue Tech uses ultrasonic technology to reduce membrane fouling and can significantly lower the costs associated with membrane maintenance and replacement. The elements will allow industrial companies and municipalities to filter and purify more water, wastewater, seawater, milk, and other liquids with less money. They provide maintenance,chemicals, downtime, and waste disposal. They serving systems and plants treating.
  • Green Steel Environmental — Green Steel delivers innovative wastewater treatment solutions and plants designed for industrial sustainability, efficiency, and environmental compliance.
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DeNovo Ventures
VC Fund · Saratoga, California, United States · 10 investments in United States Medical Device startups

DeNovo Ventures was formed in 2000 by seasoned investors and experienced medical device entrepreneurs who sought to share the lessons learned from a history of successful investing and building successful companies. They believed that their unique combination of skills and perspectives could help entrepreneurs to build companies which would havesignificant clinical impact and generate superior returns. Seven years later, this belief continues to hold true, demonstrated by investment success in selected medical device and biotechnology companies. With $650 million under management, De Novo has made more than 40 investments in medical devices and biotechnology across three funds. They invest in all stages of enterprise development and growth – from early stage to late stage. The unique background of leading companies as entrepreneurs and operating executives from start to exit enables us to advise entrepreneurs and management teams over the full life cycle of the company.

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Investment focus

  • Industry: Health Care, Medical Device, Biotechnology
  • Stage:Series B, Series D, Series C
  • Geography: United States

Investor stats

  • Total investments: 65
  • Lead/follow: no public data

Portfolio highlights

  • Avedro — Glaukos works relentlessly to create and deliver transformative therapies for patients struggling with glaucoma, corneal disorders, and retinal diseases.
  • Milo — Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.
  • Spinal Kinetics — The artificial disc replacement device from Orthofix is changing the lives of people suffering from spinal pain. Learn about this motion-saving product.
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Medical Device Investor funding in United States at a glance

Stats across 6.3k deals from 4.7k investors.

4.7k
investors
in United States Medical Device startups
6.3k
deals
in United States Medical Device startups
$7M
median round
in United States Medical Device startups
41%
lead investors
lead at least one round
16%
Seed
most common funding stage
89/11
VC / Angel
share of investor count

Access all 4731 investors in United States Medical Device startups.

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