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Top 50 Medical Device Startup Investors in United States (June 2026)

The most active venture capital funds and angel investors investing in United States Medical Device startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Medical Device startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Innova Memphis
VC Fund
71 United States, Argentina, United Kingdom Seed, Pre-Seed Health Care, Medical, Medical Device $25k–$1.7M
Portfolia
VC Fund
21 United States, Canada, Argentina Seed, Series A, Series B Health Care, Biotechnology, Software $347k–$59M
SOSV
VC Fund
20 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
TEDCO
VC Fund
19 United States, Canada, United Kingdom Seed, Pre-Seed, Grant Health Care, Software, Biotechnology $25k–$2.5M
HealthTech Capital
VC Fund
19 United States, Canada Seed, Series A, Convertible Note Health Care, Medical Device, Medical $1M–$16M
Broadview Ventures
VC Fund
18 United States, Canada, Israel Series A, Seed, Series B Health Care, Biotechnology, Medical Device $1M–$45M
CincyTech
VC Fund
17 United States Seed, Series A, Series B Software, Health Care, Biotechnology $250k–$30M
North Coast Ventures
VC Fund
16 United States Series A, Seed Health Care, Software, Medical Device $350k–$10M
Texas HALO Fund
VC Fund
15 United States, Canada, Hungary Seed, Convertible Note, Series A Health Care, Medical Device, Software $105k–$10M
Wavemaker 360
VC Fund
15 United States, United Kingdom, Canada Seed, Series A Health Care, Medical, Medical Device $700k–$16M
Maine Angels
VC Fund
15 United States Seed, Series A Software, Health Care, Biotechnology $25k–$5.9M
Oxford Finance LLC
VC Fund
15 United States, United Kingdom, Canada Debt Financing, Post-IPO Debt, Series B Biotechnology, Health Care, Medical $5M–$125M
MB Venture Partners
VC Fund
15 United States, Israel Seed, Series B, Series C Health Care, Medical, Medical Device $50k–$28M
Arboretum Ventures
VC Fund
15 United States, Canada, Israel Series B, Series A, Series C Health Care, Biotechnology, Medical $4.4M–$80M
Connecticut Innovations
VC Fund
15 United States, Israel, Canada Seed, Series A Health Care, Biotechnology, Software $200k–$25M
Boston Harbor Angels
VC Fund
14 United States, Canada, India Angel, Seed, Series A Biotechnology, Health Care, Medical Device $100k–$6M
Good Growth Capital
VC Fund
14 United States, France, Israel Seed, Series A, Convertible Note Health Care, Biotechnology, Software $25k–$24M
Versant Ventures
VC Fund
13 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $4.7M–$108M
Khosla Ventures
VC Fund
13 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, Health Care $2M–$100M
Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund
13 United States Seed, Grant, Debt Financing Health Care, Software, Information Technology $5k–$2.2M
Catalyst Health Ventures
VC Fund
13 United States Series B, Series A, Series C Health Care, Medical Device, Medical $1.3M–$85M
U.S. Venture Partners
VC Fund
12 United States, Israel, Canada Series B, Series C, Series A Software, Health Care, Information Technology $5M–$68M
Gaingels
VC Fund
12 United States, Canada, Mexico Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1.5M–$100M
Life Science Angels
VC Fund
12 United States, Israel, The Netherlands Seed, Series A Biotechnology, Health Care, Medical $1M–$20M
Horizon Technology Finance
VC Fund
12 United States, Canada, India Debt Financing, Post-IPO Debt Health Care, Biotechnology, Medical Device $5M–$40M
Wisconsin Investment Partners
VC Fund
12 United States, Canada, United Kingdom Seed, Series A Health Care, Biotechnology, Medical $400k–$7M
Alumni Ventures
VC Fund
12 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.4M–$86M
Sand Hill Angels
VC Fund
12 United States, Canada, Japan Seed, Series B, Series A Health Care, Software, Biotechnology $1M–$100M
Kleiner Perkins
VC Fund
11 United States, China, United Kingdom Series B, Series A, Series C Software, Health Care, Information Technology
Hatteras Venture Partners
VC Fund
11 United States, Canada Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$90M
Third Rock Ventures
VC Fund
11 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $11M–$150M
Rev1 Ventures
VC Fund
11 United States, Germany Seed, Series A Software, Health Care, Information Technology $192k–$18M
Asset Management Ventures (AMV)
VC Fund
11 United States, Cyprus, Ireland Series A, Seed, Series B Health Care, Biotechnology, Medical $500k–$35M
Houston Angel Network
VC Fund
11 United States, Canada, France Seed, Series A Health Care, Software, Medical $25k–$5M
New York Angels
VC Fund
11 United States, Israel, United Kingdom Seed, Series A, Series B Software, Health Care, Mobile $450k–$19M
TCA Venture Group
VC Fund
11 United States, Canada Seed, Convertible Note Software, Health Care, Biotechnology $50k–$4.5M
Sante Ventures
VC Fund
10 United States, Canada, Japan Series A, Series B, Series C Health Care, Medical, Biotechnology $1.9M–$80M
DeNovo Ventures
VC Fund
10 United States Series B, Series D, Series C Health Care, Medical Device, Biotechnology
Morgenthaler Ventures
VC Fund
10 United States, Canada, France Series B, Series A Health Care, Biotechnology, Medical
Oxford Bioscience Partners
VC Fund
10 United States, Germany, Switzerland Series B, Series C, Series A Health Care, Biotechnology, Pharmaceutical $3.5M–$50M
Keiretsu Forum
VC Fund
10 United States, India, Turkey Seed, Series A Health Care, Software, Biotechnology $102k–$8.6M
Emergent Medical Partners
VC Fund
10 United States, France Series C, Series A, Series B Health Care, Medical Device, Medical
Three Arch Partners
VC Fund
10 United States, Belgium Series B, Series C Health Care, Biotechnology, Medical Device
Virginia Venture Partners
VC Fund
10 United States, Canada, France Seed, Series A Software, Health Care, SaaS
Boutique Venture Partners
VC Fund
10 United States, Canada, France Seed, Series A, Pre-Seed Health Care, Medical, Biotechnology $2.5M–$31M
Shangbay Capital
VC Fund
10 United States, China, Canada Series A, Series B Health Care, Medical Device, Medical $5.1M–$123M
Canaan Partners
VC Fund
10 United States, United Kingdom, Israel Series A, Series B, Series C Software, Biotechnology, Health Care $5M–$75M
St. Louis Arch Angels
VC Fund
10 United States, Argentina Seed, Series A Biotechnology, Health Care, Medical Device $100k–$8.5M
Rockies Venture Club
VC Fund
10 United States, Canada Seed, Series A, Convertible Note Software, Health Care, Medical Device $250k–$7M
The Vertical Group
VC Fund
10 United States, Israel Series B, Series C Health Care, Medical Device, Medical $1.5M–$77M
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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Innova Memphis
VC Fund · Memphis, Tennessee, United States · 71 investments in United States Medical Device startups

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Pre-Seed
  • Geography: United States, Argentina, United Kingdom

Investor stats

  • Total investments: 250
  • Round size: Seed $50k–$1.7M; Pre-Seed $25k–$1.3M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
  • Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.
  • Soiltech Wireless — Soiltech Wireless is a developer of ag-tech solutions to design electronic devices for agricultural professionals. Its product provides real-time data to drive efficiency and optimize quality. It also provides actionable data without installation hassles and creates scalable monitoring solutions for farmers.The company was founded in 2019 and isheadquartered in Rupert, Idaho.
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Portfolia
VC Fund · San Mateo, California, United States · 21 investments in United States Medical Device startups

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Argentina

Investor stats

  • Total investments: 179
  • Round size: Seed $1.3M–$4.3M; Series A $347k–$15M; Series B $9M–$59M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely still investing — raised $722k in 2022

Portfolio highlights

  • Kanarys — Kanarys fuels progress towards more diverse, equitable and inclusive workplace cultures
  • Mi Padrino — Mi Padrino is an event planning service to help parents and families organize, plan, and fund events celebrated in the Hispanic tradition. They help you organize and share the details of your events with your friends and family around the globe, instantly. Your loved ones can be a part of your celebration no matter where they are in the world.KimGamez, the CEO and founder of Mi Padrino, saw a need for a more efficient solution for organizing Quinceañeras, Weddings, Baptisms, and more for the Hispanic community. As a mother of 5, Kim appreciates the complexity of coordinating all aspects of these time honored traditions with families near and far.Mi Padrino is a one of a kind solution to plan and share your special day and they are so excited to offer this easy event planning platform to simplify this age-old tradition.
  • Canela Media — Tech & innovation driven media company Leader in multicultural video reaching more than 45m uniques
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SOSV
VC Fund · Princeton, New Jersey, United States · 20 investments in United States Medical Device startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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TEDCO
VC Fund · Columbia, Maryland, United States · 19 investments in United States Medical Device startups

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Pre-Seed, Grant
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 221
  • Round size: Seed $100k–$2.5M; Grant $25k–$1M; Pre-Seed $25k–$900k
  • Lead/follow: 61% lead, 39% follow

Portfolio highlights

  • Worlds of Hello — Join Worlds of Hello, extending language growth beyond the session for children aged 2-5, using AI, NLP, and speech recognition to create personalized, inclusive learning experiences. Ideal for early childhood development and kids with speech delays.
  • Allegany College of Maryland — The main campus of the Allegany College of Maryland rests in Cumberland, off of Willow Brook Road. As the biggest of the school’s three campuses, Cumberland has all of the amenities you may never have expected from a small college. Each building is equipped with the latest modern facilities, making for an up-to-date learning experience. There arealso dining areas, a student lounge, and a state of the art physical education building with a gym and swimming pool.Within the list of extensive fields of study are the social, biological and political sciences, criminal justice and criminology, many fields in the humanities, accounting and business programs, automotive and other technical studies, culinary arts, hotel and restaurant management, forest technology, health fields including dental hygiene, physical education, nursing, and pharmacy technician studies, and more. Advice is not something you’ll be lacking at Allegany. The tutoring services can help you through any academic rough patches. Transfer advising can prepare you to go to a four-year college. Career advising counselors can help you pick a major, assess your interests and aptitudes, and help find you a career.Along with federal financial aid and veteran’s benefits, Allegany also offers a catalog full of scholarships from major related aid to local endowments to eligible students.
  • Carroll County Public Library — Carroll County Public Library offers a variety of services, including meeting and study room space, interlibrary loans,
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HealthTech Capital
VC Fund · Los Altos Hills, California, United States · 19 investments in United States Medical Device startups

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 93
  • Round size: Seed $1M–$3.4M; Series A $1.6M–$16M
  • Lead/follow: 11% lead, 89% follow

Portfolio highlights

  • xCures — An AI-assisted platform that gathers medical records from anywhere. It extracts clinical insights, resulting in significant information gain.
  • S2 Genomics — S2 Genomics is developing spatial sequencing technology solutions for processing solid tissues for single-cell applications. It enables automated processing of raw tissues into single cells or nuclei for genomics and cell biology studies. The company's vision is to provide products that process raw tissues into samples ready for genomicanalyses.S2 Genomics was founded in 2016 and is headquartered in Livermore, CA.
  • GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
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Broadview Ventures
VC Fund · Boston, Massachusetts, United States · 18 investments in United States Medical Device startups

Broadview Ventures, Inc. (Broadview) was established in 2008 as a new program conceived by the Leducq family. Through Broadview, the trust will work to accelerate the development of promising technology in cardiovascular and neurovascular disease through targeted investment in and support of early stage technology ventures.The FoundationLeducq, based in Paris, France, is the beneficiary of a charitable trust. In order to further the Foundation Leducq's mission in cardiovascular and neurovascular disease, the trust has made funds available to Broadview to develop a program which will promote early state technology in these fields through investments, licensing agreements and consortium funding arrangements, as well as professional, management and consulting support.With this initiative the trust joins other leaders in the venture philanthropy movement in seeking creative solutions to the problem of what is commonly referred to as the 'translational gap', a significant component of which is a lack of funding at a critical moment in the development of new technology and science.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 76
  • Round size: Seed $1M–$9.8M; Series A $1M–$20M; Series B $7M–$45M
  • Lead/follow: 29% lead, 71% follow

Portfolio highlights

  • FineHeart — Our mission is to address the unmet need of patients with sever heart failure
  • 480 Biomedical — 480 Biomedical focuses on the development of a bioresorbable scaffold for treating occlusive disease in the superficial femoral artery (SFA). Its lead product, SFA scaffold, is a proprietary scaffold and delivery system for use in treating peripheral arterial disease in the SFA. The company was founded in 2011 and is based in Watertown,Massachusetts.
  • HAYA Therapeutics — Pioneering next-generation therapies for fibrotic diseases. Learn more about our approach here.
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CincyTech
VC Fund · Cincinnati, Ohio, United States · 17 investments in United States Medical Device startups

CincyTech helps to identify and transform innovation into venture-worthy, transformational human health and technology companies, primarily in southwest Ohio. Our team provides advice and capital to entrepreneurs, helps research institutions commercialize technology through startups, and catalyzes investment from individuals and institutions intoregional companies. One of the most active seed funds in the Midwest, CincyTech is supported by Ohio Third Frontier, more than two dozen foundations, corporations, municipalities and individuals as well as founding partners, Cincinnati Children’s Hospital Medical Center, the University of Cincinnati, and the Cincinnati USA Regional Chamber.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Seed, Series A, Series B
  • Geography: United States

Investor stats

  • Total investments: 120
  • Round size: Seed $250k–$3.5M; Series A $300k–$30M; Series B $2.5M–$11M
  • Lead/follow: 54% lead, 46% follow
  • Last fund: Likely still investing — raised $12M in 2023

Portfolio highlights

  • Amify — We help brands selling on Amazon maximize sales and profitability by providing complete strategy, management and operational services.
  • Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
  • TeamCentral — TeamCentral is a company focused on optimizing productivity through improvements in how data is managed and governed across business systems.
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North Coast Ventures
VC Fund · Cleveland, Ohio, United States · 16 investments in United States Medical Device startups

North Coast Ventures (formerly North Coast Angel Fund) is comprised of four contributed capital funds with a focus on early-stage technology investments. Our membership consists of a number of Ohio's leading investors, entrepreneurs, and business leaders who are dedicated to accelerating early-stage ventures.North Coast Ventures members playan active role by generating deal flow, serving on due diligence teams, working with portfolio companies, or serving on the Investment Screening and Executive Committees. Through this involvement, our goal is to provide a supportive environment for our portfolio companies and ultimately enhance the performance of our Fund.Northeast Ohio has a long tradition of active and successful angel investing, but until recently, the success of this crucial form of funding has hinged on the efforts of a relatively small number of individual investors. As the region’s first professionally managed angel fund, North Coast Angel Fund works to improve the early-stage funding environment for both entrepreneurs and investors.

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Investment focus

  • Industry: Health Care, Software, Medical Device
  • Stage:Series A, Seed
  • Geography: United States

Investor stats

  • Total investments: 97
  • Round size: Seed $350k–$4.5M; Series A $1.2M–$10M
  • Lead/follow: 21% lead, 79% follow
  • Last fund: May invest from a new fund soon — last raise in 2013

Portfolio highlights

  • 1Logtech — 1Logtech provides an AI-driven self-service connectivity platform for EDI and API integrations in logistics. The solution allows operational teams, without coding expertise, to build and manage integrations with carriers, customers, TMS, ERP, and WMS systems.
  • InnerActiv — InnerActiv is a cybersecurity software company that protects organizations from insider threats, fraud, and data loss at the endpoint. Built with an AI-driven, behavior-based approach, InnerActiv delivers real-time visibility into how users interact with sensitive data, systems, and devices—detecting risky activity such as data grazing, policytesting, and low-and-slow reconnaissance before it leads to a breach. The platform’s lightweight, encrypted agents and endpoint-first design provide proactive protection, faster response, and seamless integration with existing security stacks.
  • OnStation — Productivity app for roadway workers and that provides instant jobsite location, access to plans and design, and a team chat platform.
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Texas HALO Fund
VC Fund · Houston, Texas, United States · 15 investments in United States Medical Device startups

Early Stage Venture Investments

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Investment focus

  • Industry: Health Care, Medical Device, Software
  • Stage:Seed, Convertible Note, Series A
  • Geography: United States, Canada, Hungary

Investor stats

  • Total investments: 92
  • Round size: Seed $105k–$3M; Series A $3M–$10M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — raised $175k in 2021

Portfolio highlights

  • Flourish Care — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
  • Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
  • Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.
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Wavemaker 360
VC Fund · Pasadena, California, United States · 15 investments in United States Medical Device startups

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Series A
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 77
  • Round size: Seed $700k–$6M; Series A $1.9M–$16M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: Likely still investing — raised $64M in 2022

Portfolio highlights

  • FreeNav, Inc. — FreeNav is simplifying and standardizing the position tracking of procedural instrumentation for medical applications and procedures.
  • Hermes Health — Big IdeaHermes Health is a secure, neutral middleware platform that simplifies and standardizes access to identified patient health data. We connect Requestors (e.g., attorneys, CROs, analytics firms) with Partners (e.g., ROI vendors, EHR providers, RWD sources) who hold and manage this data.ProblemAccessing identified health data remainslargely manual and outdated—relying on phone calls, faxes, and mailed records. This process is fragmented, costly, and inefficient. Requestors face a maze of disconnected workflows, while Partners are bogged down by inconsistent standards and manual tasks.SolutionHermes Health offers a scalable API and the Unity Platform to power secure, patient-consented data workflows. We reduce integration complexity and contractual friction by enabling seamless connectivity between Requestors and our network of Partners.The Unity Platform integrates with Partners as they are—plugging into existing APIs or co-developing new ones to match their systems. Whether you're a requestor or a data custodian, Hermes Health accelerates access while preserving security and compliance.
  • Esperto Medical — Esperto Medical is an Irvine, CA-based medical device company developing next-generation wearable diagnostics that enable hospital-based and remote patient monitoring with unprecedented ease and accuracy. Its unique resonance sonomanometry technology uses acoustic stimulation to directly and noninvasively measure continuous blood pressure withoutcalibration.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

Browse database — It's Free!
Maine Angels
VC Fund · Portland, Maine, United States · 15 investments in United States Medical Device startups

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Seed, Series A
  • Geography: United States

Investor stats

  • Total investments: 128
  • Round size: Seed $25k–$773k; Series A $662k–$5.9M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
  • TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
  • Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.
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Oxford Finance LLC
VC Fund · Alexandria, Virginia, United States · 15 investments in United States Medical Device startups

Providing Flexible and Creative Financial Solutions to Middle Market Companies.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Debt Financing, Post-IPO Debt, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 117
  • Round size: Series B $39M–$76M; Post-IPO Debt $15M–$125M; Debt Financing $5M–$75M
  • Lead/follow: 50% lead, 50% follow

Portfolio highlights

  • Inhibrx — Inhibrx is a clinical-stage biotechnology company focused on developing a broad pipeline of novel biologic therapeutic candidates. Inhibrx utilizes diverse methods of protein engineering to address the specific requirements of complex target and disease biology, including its proprietary sdAb platform. The Inhibrx pipeline is focused on oncology,orphan diseases and infectious diseases. Inhibrx has collaborations with Celgene and bluebird bio and has received awards from several granting agencies, including NIH, NIAID and CARB-X.
  • Vortexa — State of the art energy analytics that paints a global picture of cargo flows. Identify energy market opportunities before the competition with Vortexa.
  • Headspace — Live a healthier, happier, more well-rested life in just a few minutes a day. Get the science-backed mental health app for every moment. Try for free.
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MB Venture Partners
VC Fund · Memphis, Tennessee, United States · 15 investments in United States Medical Device startups

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Series B, Series C
  • Geography: United States, Israel

Investor stats

  • Total investments: 90
  • Round size: Seed $50k–$700k; Series B $1.3M–$18M; Series C $5M–$28M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — raised $22M in 2011

Portfolio highlights

  • Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
  • SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
  • Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.
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Arboretum Ventures
VC Fund · Ann Arbor, Michigan, United States · 15 investments in United States Medical Device startups

For over 20 years we have been a successful healthcare venture capital firm rooted in the Midwest. Check out our portfolio companies.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Canada, Israel

Investor stats

  • Total investments: 112
  • Round size: Series A $4.4M–$27M; Series B $5M–$50M; Series C $10M–$80M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: May invest from a new fund soon — raised $250M in 2019

Portfolio highlights

  • Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
  • Boomerang Medical — Boomerang Medical is a bioelectronic medicine company targeting autoimmune diseases.
  • Allay Therapeutics — SUPPORTING PATIENTS THROUGH EVERY PHASE OF RECUPERATION The first technology designed to deliver weeks of localized pain management
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 15 investments in United States Medical Device startups

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 245
  • Round size: Seed $200k–$5M; Series A $2.4M–$25M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $50M in 2023

Portfolio highlights

  • Device42 — Device42 sets the standard as the most comprehensive, agentless discovery and dependency mapping solution, spanning from legacy mainframes to cloud containers.
  • Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
  • NovaTract Surgical — NovaTract Surgical is a development stage company, intends to develop medical devices to address the rapidly growing field of Single Incision Laparoscopic Surgery (SILS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES). The company was incorporated in 2010 and is based in Guilford, Connecticut.
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Boston Harbor Angels
VC Fund · Boston, Massachusetts, United States · 14 investments in United States Medical Device startups

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical Device
  • Stage:Angel, Seed, Series A
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 105
  • Round size: Seed $100k–$2.4M; Angel $500k–$1.6M; Series A $662k–$6M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
  • Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
  • Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.
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Good Growth Capital
VC Fund · Charleston, South Carolina, United States · 14 investments in United States Medical Device startups

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, France, Israel

Investor stats

  • Total investments: 111
  • Round size: Seed $505k–$8.2M; Series A $4.2M–$24M; Convertible Note $25k–$300k
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely still investing — raised $100M in 2023

Portfolio highlights

  • Pryon — Pryon is the leading AI-as-a-Service platform for content and knowledge management. Pryon closes knowledge gaps, improving employee productivity, and enhancing customer experiences. Companies such as Georgia Pacific use Pryon to improve health and safety outcomes, eliminate compliance incidents, improve employee onboarding, and upgrade all aspectsof customer service and support.
  • Obsidio — Obsidio™ Conformable Embolic with aqueous gel technology is a 510(k) cleared device, the first of its kind to have a specific on-label indication for peripheral use in the U.S.
  • AdipoPharma — AdipoPharma SAS is dedicated to learning more about the role of adipocyte cells in diabetes. AdipoPharma is using the adipocyte's power to treat insulin resistance, type 2 diabetes, and other diseases.
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Versant Ventures
VC Fund · Menlo Park, California, United States · 13 investments in United States Medical Device startups

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 278
  • Round size: Series A $4.7M–$80M; Series B $10M–$105M; Series C $12M–$108M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Achaogen — Achaogen is a clinical stage biopharmaceutical company focused on the discovery and development of broad-spectrum antibiotics to treat multi-drug resistant bacterial infections. The company's most advanced drug candidate, ACHN-490, has demonstrated a positive safety and dosing profile in Phase 1 clinical testing and displayed broad spectrumefficacy in preclinical studies against systemic infections caused by multi-drug resistant (MDR) Gram-negative bacteria (e.g., E. coli, K. pneumoniae, and P. aeruginosa) and MRSA. In addition, the company is pursuing preclinical programs in several other areas of interest to combat the global emergence of bacterial resistance.
  • Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
  • Dayra Therapeutics
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 13 investments in United States Medical Device startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1050
  • Round size: Seed $2M–$15M; Series A $5.5M–$40M; Series B $10M–$100M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely still investing — raised $557M in 2022

Portfolio highlights

  • Hunch — Hunch is a consumer web application that is building the "taste graph" of the internet, mapping every person on the internet to every entity on the internet and their affinity for that entity. An entity could be a web site, a cookbook, a hotel room, a celebrity, a restaurant, etc.Hunch creates a taste profile by asking them a seriesof questions which range from serious to profound and subsequently can make recommendations personalized to that user, which live in "topics".Topics vary widely, from entertaining subjects like 'Which superhero would you be' to more conventional questions like 'Should I Switch to A Mac?' The system then uses the answers to these questions to offer the user a suggested solution, a "hunch" of what the user would like.
  • Speak — People spend $90 billion a year on human english teachers that are expensive and ineffective. Speak offers a mobile app where you can have english conversations with your phone about real world scenarios like interviewing for a job or asking for directions. It uses speech recognition to identify english words through thick accents and teach peopleto speak more clearly. Meanwhile, it’s building a massive database of accented-english speech, which can be used to improve its system and other speech recognition systems. Speak’s team formerly built accent detection systems and sold Flashcards+ to Chegg. Though AI translation might reduce the need for people to know other languages, speaking English remains a valuable skill people are willing to pay for.
  • The Climate Corporation (Bayer Crop Science) — The Climate Corporation (formerly WeatherBill) aims to help farmers around the world protect and improve their farming operations with uniquely powerful software, hardware and insurance products. The company’s proprietary Climate Technology Platform combines hyper-local weather monitoring, agronomic modeling, and high-resolution weather simulationsto deliver Climate Basic and Climate Pro, mobile SaaS solutions that helps farmers improve profitability by making better informed operating and financing decisions.
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Ben Franklin Technology Partners of Southeastern Pennsylvania
VC Fund · Philadelphia, Pennsylvania, United States · 13 investments in United States Medical Device startups

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

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Investment focus

  • Industry: Health Care, Software, Information Technology
  • Stage:Seed, Grant, Debt Financing
  • Geography: United States

Investor stats

  • Total investments: 137
  • Round size: Seed $100k–$2.2M; Grant $5k–$100k; Debt Financing $975k–$975k
  • Lead/follow: 39% lead, 61% follow

Portfolio highlights

  • CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
  • SFA Therapeutics — SFA Therapeutics is developing a next-generation oral immune tolerance therapy for psoriasis. Our investigational approach is designed to restore immune tolerance at its source, targeting the underlying immune dysfunction rather than broadly suppressing the immune system. Supported by early human results, our platform aims to deliver a more precise, patient-friendly treatment option for chronic inflammatory disease.
  • Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.
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Catalyst Health Ventures
VC Fund · Braintree, Massachusetts, United States · 13 investments in United States Medical Device startups

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States

Investor stats

  • Total investments: 45
  • Round size: Series A $1.4M–$19M; Series B $2.3M–$33M; Series C $1.3M–$85M
  • Lead/follow: 53% lead, 47% follow
  • Last fund: May invest from a new fund soon — raised $75M in 2019

Portfolio highlights

  • Venova Medical — Venova Medical, Inc. is a privately held company addressing the challenges associated with providing optimal vascular access for patients that need hemodialysis.
  • Esperto Medical — Esperto Medical is an Irvine, CA-based medical device company developing next-generation wearable diagnostics that enable hospital-based and remote patient monitoring with unprecedented ease and accuracy. Its unique resonance sonomanometry technology uses acoustic stimulation to directly and noninvasively measure continuous blood pressure withoutcalibration.
  • Brixton Biosciences — Brixton Biosciences is a biotechnology company currently operating in stealth mode.
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U.S. Venture Partners
VC Fund · Menlo Park, California, United States · 12 investments in United States Medical Device startups

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series C, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 402
  • Round size: Series A $5M–$40M; Series B $7M–$50M; Series C $6M–$68M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Nervonik — Explore Nervonik neuromodulation devices that are working to redefine peripheral nerve stimulation with advanced technology for high motion.
  • Route 92 Medical — The official website for Route 92 Medical.
  • Cleave Therapeutics — Cleave Therapeutics develops oncology pharmaceuticals designed to target neurodengeneration and pathways used by cancer cells to grow. The company is engaged in the discovery of novel, small-molecule drugs that affect protein-degradation pathways, upon which cancer cells depend for survival, enabling patients to get cured from cancer.
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Gaingels
VC Fund · New York, New York, United States · 12 investments in United States Medical Device startups

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 687
  • Round size: Seed $1.5M–$8M; Series A $6M–$43M; Series B $16M–$100M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Epirus — Epirus is a high-growth technology company that develops cutting-edge directed energy systems and power management solutions to transform multiple industries.
  • Operant — Own OperantAi.com today. Secure checkout and guided transfer support. No hidden fees.
  • Quadient Accounts Receivable by YayPay — YayPay accounts receivable automation software helps businesses collect faster, forecast cash flow accurately, and improve payment process. Automate your AR
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Life Science Angels
VC Fund · Sunnyvale, California, United States · 12 investments in United States Medical Device startups

Life Science Angels, Inc. (LSA) is the premier angel investment group focused solely on healthcare investing, including medical devices, diagnostics, pharmaceuticals, biotechnology, and digital health.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A
  • Geography: United States, Israel, The Netherlands

Investor stats

  • Total investments: 84
  • Round size: Seed $1M–$4M; Series A $1.3M–$20M
  • Lead/follow: 10% lead, 90% follow

Portfolio highlights

  • Neurava — Neurava has developed wearable diagnostics for epilepsy patients including those at risk of SUDEP. The company specializes in the fields of medical device manufacturing, healthcare, and health diagnostics.
  • Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
  • Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.
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Horizon Technology Finance
VC Fund · Farmington, Connecticut, United States · 12 investments in United States Medical Device startups

Horizon is a venture lending platform that offers structured debt products to life science and technology companies. Its team of investment and operations professionals has been providing debt capital to some of the most exciting companies for decades. The members of the Horizon team have, collectively, originated and invested more than $5 billionin venture loans to thousands of companies.The company was founded in 2003 and is headquartered in Farmington, Connecticut.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Debt Financing, Post-IPO Debt
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 103
  • Round size: Post-IPO Debt $10M–$40M; Debt Financing $5M–$30M
  • Lead/follow: 69% lead, 31% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • Stellar Cyber — Stellar Cyber: Automation-Driven, Open & Unified SecOps Platform with AI SIEM, NDR, Open XDR, and Multi-Layer AI.
  • Hyperfine — Hyperfine makes MRI accessible to every patient regardless of income or resources.
  • Onkos Surgical — Onkos Surgical is a privately-held surgical oncology company that brings new technology and solutions to surgical oncologists. There are huge opportunities for innovation where the complexity of the disease state requires more diverse solutions. Onkos Surgical will be 100% focused on bringing new technology and solutions to surgical oncologists whoserve a population of which a large portion of the patients are children and the broader population may require personalized solutions.
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Wisconsin Investment Partners
VC Fund · Madison, Wisconsin, United States · 12 investments in United States Medical Device startups

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 115
  • Round size: Seed $400k–$3M; Series A $1.1M–$7M
  • Lead/follow: 15% lead, 85% follow

Portfolio highlights

  • DropCap — DropCap is a tech-enabled rights agency (dropcap.com) and a global rights marketplace used by rights agents and acquisitions editors around the world to find great books (dropcapmarketplace.com). Our mission is to provide independent authors and publishers access to rights licensing opportunities and help indie books go global through foreignrights, audio, and film rights licensing.
  • Cylerity — Transform healthcare receivables into real-time capital. Cylerity unlocks cash flow, clarity, and control from claims data. See how it works.
  • Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.
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Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 12 investments in United States Medical Device startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 1378
  • Round size: Seed $1.4M–$10M; Series A $5M–$37M; Series B $12M–$86M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Humio — Humio operates as a time-series logging and aggregation platform designed for unrestricted and comprehensive event analysis. It is deployable on any infrastructure including both in the cloud and on-premises. Humio enables data aggregation, exploration, reporting, and analysis from a range of sources ingesting massive volumes of log data instantly.Its data storage and in-memory search/query engine technologies provide customers cost-competitive log management and analysis solution, all while requiring significantly less hardware and engineering resources.The company was founded in 2016 and is headquartered in London, England.
  • OpusClip — Opus Clip turns long videos into high-quality viral clips for you to share on TikTok, YouTube Shorts, and Reels to increase social media reach.
  • Arda Therapeutics — Arda Therapeutics is a biotechnology company taking aim at chronic diseases and aging by eliminating the pathogenic cells that drive these conditions. Their approach starts by using single-cell data to identify pathogenic cells and specific markers to target them. They then design therapies to eliminate these - and only these - cells.Arda wasfounded in 2021 in the San Francisco Bay Area, CA.
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Sand Hill Angels
VC Fund · Mountain View, California, United States · 12 investments in United States Medical Device startups

For over two decades, Sand Hill Angels has worked openly and collaboratively with venture capital funds, other angel organizations, and the Bay Area ecosystem that fosters the growth of technology startups.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series B, Series A
  • Geography: United States, Canada, Japan

Investor stats

  • Total investments: 227
  • Round size: Seed $1M–$6.5M; Series A $1.4M–$18M; Series B $8.5M–$100M
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • SellHound — SellHound is a price comparison engine for secondhand marketplaces that makes it easy to sell second-hand items. Its product includes a multi-marketplace virtual assistant listing app for used goods, as well as, the first-ever aggregator of secondhand marketplaces. Their smart recommerce platform is designed to make selling as easy as buying.Our goal is to make reuse more mainstream by making recommerce easier and more successful for everyone.It was founded in 2017 and is headquartered in Santa Cruz, California.
  • Lincode — The #1 business challenge that manufacturers identify is quality management. As new manufactured products continue to enter the market and consumer expectations shift faster than ever, factories are looking to improve their quality systems while scaling operations and cutting costs. At Lincode, we enable manufacturers to improve the speed, accuracy, and data tracking capabilities of their quality inspection systems at scale.
  • Clean Power Finance — Clean Power Finance (CPF) is building an online business-to-business marketplace to drive the mass-market adoption of solar. The company connects providers of capital who are committed to investing in residential solar with qualified solar marketers, installers and distributors who need residential solar finance products to differentiate and growtheir businesses. CPF raises 100 percent third-party‐owned project finance funds from institutional investors such as Morgan Stanley and Google, working with the investors to structure and launch the funds with managed risk and return profiles. CPF then markets the funds as solar leases and power purchase agreements (PPAs) to qualified solar professionals, including Paramount Solar and Real Goods Solar (Nasdaq: RSOL), through its licensed online solar sales platform, CPF Tools. CPF Tools is software-as-a-service that simplifies complex sales, quoting, proposal and finance processes and minimizes the “soft costs” of selling solar.CPF’s fund investors earn favorable returns on stable investments on the resulting portfolios of residential distributed generation projects. The company’s solar professional partners gain access to solar leases and power purchase agreements (PPAs) that they can brand and sell to homeowners who want the benefits of solar without the cost and hassle of owning and maintaining a system.CPF manages approximately half a billion dollars of capacity on behalf of fund investors, and supports more than 100 solar professional customers who currently use the CPF Market to sell residential solar finance products to homeowners in CA, CO, HI, MA and NJ. Thousands of solar professionals in all 50 states have extensively used CPF Tools to quote and design solar systems.
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Kleiner Perkins
VC Fund · Menlo Park, California, United States · 11 investments in United States Medical Device startups, 34 in the past 12 months

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 1031
  • Lead/follow: no public data

Portfolio highlights

  • Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
  • Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
  • Hippocratic AI — The First Safety Focused LLM for Healthcare
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Hatteras Venture Partners
VC Fund · Durham, North Carolina, United States · 11 investments in United States Medical Device startups

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada

Investor stats

  • Total investments: 128
  • Round size: Series A $5.2M–$41M; Series B $5M–$90M; Series C $8M–$88M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Ribometrix — The Next Frontier of Drug Discovery
  • Contego Medical — Better Outcomes. Simplified. Neurovascular Peripheral Vascular Neurovascular
  • G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 11 investments in United States Medical Device startups

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 144
  • Round size: Series A $17M–$102M; Series B $11M–$150M; Series C $14M–$146M
  • Lead/follow: 44% lead, 56% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.
  • Jounce Therapeutics — Concentra is a biosciences company.
  • Syremis Therapeutics
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 11 investments in United States Medical Device startups

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 191
  • Round size: Seed $192k–$3M; Series A $1.2M–$18M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $20M in 2021

Portfolio highlights

  • RedNOx — RedNOx develops breakthrough emissions reduction technology for heavy-duty engines, gensets, and agricultural equipment.
  • InnerActiv — InnerActiv is a cybersecurity software company that protects organizations from insider threats, fraud, and data loss at the endpoint. Built with an AI-driven, behavior-based approach, InnerActiv delivers real-time visibility into how users interact with sensitive data, systems, and devices—detecting risky activity such as data grazing, policytesting, and low-and-slow reconnaissance before it leads to a breach. The platform’s lightweight, encrypted agents and endpoint-first design provide proactive protection, faster response, and seamless integration with existing security stacks.
  • SureImpact — SureImpact is a user-friendly, social services case management software that helps you track and report outcomes, measure participant needs, and demonstrate impact to funders.
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Asset Management Ventures (AMV)
VC Fund · Palo Alto, California, United States · 11 investments in United States Medical Device startups

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Seed, Series B
  • Geography: United States, Cyprus, Ireland

Investor stats

  • Total investments: 143
  • Round size: Seed $500k–$6M; Series A $2.4M–$28M; Series B $5M–$35M
  • Lead/follow: 22% lead, 78% follow
  • Last fund: May invest from a new fund soon — raised $150M in 2020

Portfolio highlights

  • SeeQC — SEEQC is developing the first digital quantum computing platform for businesses. SEEQC combines classical & quantum technologies to address the efficiency, stability & cost issues endemic to quantum computing.
  • Autonomize AI — AI That Runs Healthcare. For the Humans Who Make It Work. AI-Native Infrastructure: Rewiring Healthcare Operations for the Next Era.
  • Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.
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Houston Angel Network
VC Fund · Houston, Texas, United States · 11 investments in United States Medical Device startups

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

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Investment focus

  • Industry: Health Care, Software, Medical
  • Stage:Seed, Series A
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 133
  • Round size: Seed $25k–$1.8M; Series A $240k–$5M
  • Lead/follow: 8% lead, 92% follow

Portfolio highlights

  • ITeam — iTeam is transforming the way information technology (IT) and audio/video (A/V) installation services are packaged, sold and delivered through a new approach called Service-as-a-Product™ (SaaP™).
  • Monster Mosquito — Monster Mosquito focuses on providing all-natural mosquito sentry repellent systems for its clients. The company also develops a biodegradable compound insecticide to exterminate biting insects.Monster Mosquito uses mosquito mist systems, which contains pyrethrum, a natural mosquito killer made from chrysanthemums. The company was founded in 2002by Kemper Modlin and Leo Niekerk.It is based in Spring, Texas.
  • Davidson Instruments — Davidson has designed and developed innovative temperature-tolerant pressure measurement instrumentation that is rugged, immune to electromagnetic interference, and intrinsically-safe based on patented fiber optic sensing technology. The instrumentation has been proven through numerous installations with over one million hours of time inservice. Davidson's products include instruments for making high resolution static pressure measurements and others for making high speed dynamic pressure measurements.
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New York Angels
VC Fund · New York, New York, United States · 11 investments in United States Medical Device startups

New York Angels is one of the oldest, most prominent angel investment groups in the country. New York Angels has offered early-stage entrepreneurs funding, mentoring, connections and more for over 20 years. Angel investors join New York Angels for their extensive, experienced network, increased de

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Investment focus

  • Industry: Software, Health Care, Mobile
  • Stage:Seed, Series A, Series B
  • Geography: United States, Israel, United Kingdom

Investor stats

  • Total investments: 163
  • Round size: Seed $450k–$3.9M; Series A $1.2M–$8M; Series B $2M–$19M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $1.2M in 2012

Portfolio highlights

  • Atraverse Medical
  • EndoShunt Medical — EndoShunt Medical is a provider of a medical device for targeted hemorrhage control in emergency situations. The company was founded in 2022 and is headquartered in Nashville TN, United States.
  • New View Surgical — New View Surgical is an emerging medical device company focused on the development and commercialization of the VisionPort™ System, a novel surgical imaging and access system for minimally invasive surgery. The company is led by an experienced team of medical device innovators and commercial experts who have come together to design andcommercialize impactful solutions that meet a variety of unmet market needs. The company’s proprietary VisionPort™ system combines multiple imaging and access devices into just one simple, easy-to-use device that is disposable and is expected to bring a variety of clinical and economic advantages to minimally invasive surgery operating rooms around the world.
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TCA Venture Group
VC Fund · Newport Beach, California, United States · 11 investments in United States Medical Device startups

TCA Venture Group is the largest angel investor group in the United States, possessing more than 300 members in five networks in Los Angeles, Orange County, San Diego, Central Coast, and the Inland Empire. Its members provide funding and guidance to more early-stage, high-growth companies in Southern California than any other investment group.Members invest in companies in a wide range of industries, including the life sciences, biotech, IT, services, retail, Internet, financial, software, media, consumer products, and tech startups. TCA as a whole gives companies more than just capital; they also provide counsel, mentoring, and access to an extensive network of potential investors, customers, strategic partners, and management talent. Tech Coast Angels has been ranked by CB Insights to be among the Top 20 Angel Groups in the US; TCA was also ranked as #1 for Network Centrality, meaning we have more connections than anyone! If you are in the game-changing business, we are here to help.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Seed, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 226
  • Round size: Seed $690k–$4M; Convertible Note $50k–$4.5M
  • Lead/follow: 8% lead, 92% follow
  • Last fund: May invest from a new fund soon — last raise in 2015

Portfolio highlights

  • NovaSignal — NovaSignal is a medical technology company commercializing a robotic cerebral ultrasound system. Robotic System combines non-invasive ultrasound, robotics, and artificial intelligence to assess real-time cerebral blood flow.
  • Major Medical Devices — Major Medical Devices develops next-generation vascular devices for endovascular repair and related surgical procedures.
  • Noria Water Technologies — Noria Water Technologies provides solutions for improving the operations of water-based processes. It optimizes industrial processes by shining a spotlight on critical industrial surfaces. The company was founded in 2013 and is headquartered in Los Angeles, California.
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Sante Ventures
VC Fund · Austin, Texas, United States · 10 investments in United States Medical Device startups

Privately Held Companies

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Investment focus

  • Industry: Health Care, Medical, Biotechnology
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada, Japan

Investor stats

  • Total investments: 108
  • Round size: Series A $1.9M–$29M; Series B $2.6M–$42M; Series C $3.5M–$80M
  • Lead/follow: 59% lead, 41% follow
  • Last fund: Likely still investing — raised $260M in 2021

Portfolio highlights

  • ABK Biomedical — At ABK biomedical, we are focused on developing novel Y90 radioembolization treatment options for patients with hypervascular liver tumors
  • Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.
  • SONIRE Therapeutics — SONIRE Therapeutics is a clinical-stage medical device company. It is a U.S. subsidiary of SONIRE Therapeutics Co., Ltd..
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DeNovo Ventures
VC Fund · Saratoga, California, United States · 10 investments in United States Medical Device startups

DeNovo Ventures was formed in 2000 by seasoned investors and experienced medical device entrepreneurs who sought to share the lessons learned from a history of successful investing and building successful companies. They believed that their unique combination of skills and perspectives could help entrepreneurs to build companies which would havesignificant clinical impact and generate superior returns. Seven years later, this belief continues to hold true, demonstrated by investment success in selected medical device and biotechnology companies. With $650 million under management, De Novo has made more than 40 investments in medical devices and biotechnology across three funds. They invest in all stages of enterprise development and growth – from early stage to late stage. The unique background of leading companies as entrepreneurs and operating executives from start to exit enables us to advise entrepreneurs and management teams over the full life cycle of the company.

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Investment focus

  • Industry: Health Care, Medical Device, Biotechnology
  • Stage:Series B, Series D, Series C
  • Geography: United States

Investor stats

  • Total investments: 65
  • Lead/follow: no public data

Portfolio highlights

  • Avedro — Glaukos works relentlessly to create and deliver transformative therapies for patients struggling with glaucoma, corneal disorders, and retinal diseases.
  • Milo — Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.
  • Spinal Kinetics — The artificial disc replacement device from Orthofix is changing the lives of people suffering from spinal pain. Learn about this motion-saving product.
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Morgenthaler Ventures
VC Fund · Menlo Park, California, United States · 10 investments in United States Medical Device startups

Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series B, Series A
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 225
  • Lead/follow: no public data

Portfolio highlights

  • Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
  • SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
  • Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.
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Oxford Bioscience Partners
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Medical Device startups

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Investment focus

  • Industry: Health Care, Biotechnology, Pharmaceutical
  • Stage:Series B, Series C, Series A
  • Geography: United States, Germany, Switzerland

Investor stats

  • Total investments: 109
  • Round size: Series A $3.5M–$26M; Series B $10M–$48M; Series C $5.6M–$50M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: May invest from a new fund soon — raised $66M in 2011

Portfolio highlights

  • Paperspace — Ceres, Inc. (Ceres) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks. The Company’s large-scale commercial products are sweet sorghum varieties that can be used as a drop-in feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills. Its products include sweet sorghum, high biomasssorghum, switchgrass, miscanthus and row crops. Its energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Baseload utility scale electric power can also be generated from the biomass feedstocks grown from its seeds. Ceres has sold switchgrass and high biomass sorghum seeds in the United States under its Blade Energy Crops (Blade) brand. In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda.
  • CardioFocus — CardioFocus is a biotechnology company that focuses on the advancement of ablation treatments for cardiac disorders. The company specializes in providing electrophysiologists with innovative and effective tools that bring new levels of precision and control to the treatment of atrial fibrillation that focuses on developing, manufacturing, andinvestigating disposable fiber optic catheters for the visualization of the cardiac anatomy and the treatment of cardiac arrhythmias.CardioFocus was founded in 1990 and is headquartered in Marlborough, Massachusetts.
  • Yolia Health — Yolia Health developed The True Vision Treatment or TVT, the 'Invisalign' for the eyes. A non-invasive treatment to correct vision problems like presbyopia without surgery. TVT is self-administered by the patient in his or her own home. It employs a combination of customized contact lenses (TVT Contacts) and specially formulatedeye drops (TVT Eye Drops). After only 5 days of treatment with TVT patients are able to stop using the TVT Contacts, TVT Eye Drops and their reading glasses for up to 12 months at a time before re-treatment with TVT is needed. What is even greater than correcting for presbyopia non-invasively, is correcting both eyes without compromising any distance vision. On the contrary, Yolia's treatment improves both near and distance vision, a unique feature no single other alternative can provide. ** Looking for sophisticated investors and key industry partners.
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Keiretsu Forum
VC Fund · San Francisco, California, United States · 10 investments in United States Medical Device startups

Keiretsu Forum is a global angel investor network with more than 2,500 accredited investor members throughout 47 chapters on 3 continents.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Series A
  • Geography: United States, India, Turkey

Investor stats

  • Total investments: 186
  • Round size: Seed $102k–$3.6M; Series A $778k–$8.6M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2015

Portfolio highlights

  • Bliss — Bliss is an AI-powered online therapy platform that provides online mental health and wellness services to make mental health support more accessible, affordable, and culturally sensitive. The company connects individuals with licensed therapists and mental health professionals for video, audio, and messaging-based counseling sessions. Its platformincludes therapist matching tools, secure communication systems, appointment scheduling, and multilingual support designed for users seeking culturally aligned care. Bliss supports mental health needs related to anxiety, depression, trauma, relationships, stress management, and personal development through remote therapy services. The company also offers mental wellness programs for businesses, providing employee support resources, coaching access, and digital mental health services for distributed teams. Its services are designed to make therapy and emotional support accessible through online and mobile-based interactions.
  • ActuatedMedical — Actuated Medical designs innovative medical devices that improve patient care and outcomes by solving unmet clinical needs with engineered motion.
  • Kisaan Se Kitchen Tak — Eat our pure, naturally grown, & direct farmse products, grown without use of harmful chemicals brought to directly from Kisaan Se Kitchen Tak; they'll fill your body with energy, nutrients, & antioxidants.
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Emergent Medical Partners
VC Fund · Portola Valley, California, United States · 10 investments in United States Medical Device startups

Providing funding and expertise for early-stage medical device companies.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series C, Series A, Series B
  • Geography: United States, France

Investor stats

  • Total investments: 38
  • Lead/follow: no public data

Portfolio highlights

  • Shape Memory Medical — Smart polymer. Smart embolization. Smart choice. Reshaping your view of clinical success through the science of smart polymer.
  • Standard Bariatrics — Cincinnati-based surgical procedure company focused on innovative development, commercialization of medical devices for treatment of obesity, gastrectomy.
  • Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.
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Three Arch Partners
VC Fund · Portola Valley, California, United States · 10 investments in United States Medical Device startups

Three Arch Partners was formed in 1993 to provide young companies with access to relevant clinical and business resources, as well as capital. Three Arch has helped create, build and fund more than 100 important new healthcare companies. These companies have often become the clinical and market leaders in their respective fields, and have generatedstrong returns. The fund focuses on opportunities in medical devices and healthcare services, and less frequently in biotechnology.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical Device
  • Stage:Series B, Series C
  • Geography: United States, Belgium

Investor stats

  • Total investments: 75
  • Lead/follow: no public data

Portfolio highlights

  • Nevro — Nevro is a global medical device company focused on providing innovative products that improve the quality of life of patients suffering from debilitating chronic pain. Nevro has developed and commercialized the Senza spinal cord stimulation (SCS) system, an evidence-based neuromodulation platform for the treatment of chronic pain. The Senza systemis the only SCS system that delivers Nevro's proprietary HF10 therapy. Senza, HF10, Nevro and the Nevro logo are trademarks of Nevro.
  • Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
  • Access Closure — Access Closure, Inc., a medical device company, provides access site management products to address the complex challenge of vascular closure during interventional and diagnostic procedures. The company's products include Mynx delivery system, a vascular closure device that seals the arteriotomy using a water-soluble and extravascular sealant,which expands in the tissue tract by absorbing blood and subcutaneous fluids. Access Closure, Inc. was founded in 2002 and is based in Mountain View, California.
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Virginia Venture Partners
VC Fund · Herndon, Virginia, United States · 10 investments in United States Medical Device startups

Virginia Venture Partners is a family of seed-stage investment funds placing near-equity and equity investments in Virginia-based technology, life science, and cleantech companies. Virginia Venture Partners invests in companies with a high potential for achieving rapid growth and generating significant economic returns for entrepreneurs,co-investors, and the Commonwealth of Virginia. CIT’s family of funds includes:GAP Fund I is a vintage 2004 fund fully invested in a broad array of seed-stage technology companies. Portfolio.GAP BioLife Fund is a seed fund investing exclusively in life science companies.GAP Tech Fund is a seed fund investing in IT and technology companies.

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Investment focus

  • Industry: Software, Health Care, SaaS
  • Stage:Seed, Series A
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 164
  • Lead/follow: no public data

Portfolio highlights

  • Syntrillo — Stroke is the leading cause of long-term disability worldwide, but it doesn’t have to be. We know that with the right kind of care, 8 out of 10 strokes could be prevented. Through a combination of digital health and AI, we are making expert-level care accessible to millions of at-risk patients. Our team of neurologists, rehabilitation experts, andpsychologists have made it our mission to improve your brain health and protect against stroke.
  • NearStar Fusion Inc. — NearStar Fusion is developing fusion power plants with a tritium-free pulsed impact fusion approach leveraging extensive experience with hypervelocity plasma railguns. The simplicity of the NearStar Fusion power plant reduces development time, construction, and operating costs, while improving operational reliability and longevity.NearStar's design heavily leverages existing materials and technologies thereby avoiding major investments in material science or complicated supply chains.
  • Thumbprint Furniture — Thumbprint is dedicated to simplifying the commercial furniture design and specification process.
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Boutique Venture Partners
VC Fund · Palo Alto, California, United States · 10 investments in United States Medical Device startups

Boutique Venture Partners specializes in early-stage investments in healthcare and life sciences

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Investment focus

  • Industry: Health Care, Medical, Biotechnology
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 35
  • Round size: Seed $2.5M–$5.8M; Series A $4M–$31M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • QMENTA — Our industry-leading neuroimaging cloud-based software works with advanced AI-powered tools to empower researchers, radiologists, and clinical trials.
  • miRecule — MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics. It features a genomic-based drug development platform that integrates genomic sequencing, expression, and prognostic data from cancer patients. The company was founded in 2016 and headquartered in Gaithersburg, United States.
  • Surge — SurgeCare leverages immune profiling and AI to reveal early immune signatures and drive better decisions in surgery, trauma, infection, and beyond.
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Shangbay Capital
VC Fund · Palo Alto, California, United States · 10 investments in United States Medical Device startups

ShangBay Capital is a venture capital company that brings best-in-class investments mainly in the U.S. medical devices technology, as well as biotech, and mobile healthcare sectors through early-stage venture equity participation

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series A, Series B
  • Geography: United States, China, Canada

Investor stats

  • Total investments: 45
  • Round size: Series A $5.1M–$27M; Series B $10M–$123M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: May invest from a new fund soon — raised $48M in 2021

Portfolio highlights

  • Nervonik — Explore Nervonik neuromodulation devices that are working to redefine peripheral nerve stimulation with advanced technology for high motion.
  • Petal Surgical — Petal is a surgical technology company pioneering incisionless surgery through Acoustic Sculpting, a proprietary form of boiling histotripsy. Our platform uses focused sound waves to precisely destroy harmful tissue without cuts, heat, or toxicity offering gentler alternative to traditional surgery.
  • Evident Vascular — Evident Vascular offers an advanced IVUS platform that leverages Artificial Intelligence to deliver superior Vascular.
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Canaan Partners
VC Fund · Menlo Park, California, United States · 10 investments in United States Medical Device startups

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

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Investment focus

  • Industry: Software, Biotechnology, Health Care
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 648
  • Round size: Series A $5M–$38M; Series B $7.8M–$75M; Series C $7.1M–$55M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — raised $100M in 2024

Portfolio highlights

  • CarTrade — CarTrade - Buy and Sell Used Cars in India at right price. Find New Cars, car prices, upcoming cars and images. Read latest auto news, reviews and car comparisons.
  • Matrimony.com — Revolutionizing the Indian matrimonial industry with world class matchmaking and wedding planning services. Your search for the perfect match ends here!
  • Savvy — Savvy is a software development company that engages in cybersecurity.
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St. Louis Arch Angels
VC Fund · St Louis, Missouri, United States · 10 investments in United States Medical Device startups

The St. Louis Arch Angels is a network of accredited investors who fund early-stage businesses across the St. Louis region.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical Device
  • Stage:Seed, Series A
  • Geography: United States, Argentina

Investor stats

  • Total investments: 75
  • Round size: Seed $100k–$3.3M; Series A $1.5M–$8.5M
  • Lead/follow: 43% lead, 57% follow

Portfolio highlights

  • Peptyde Bio — Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.
  • SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
  • Maximum Fidelity Surgical Simulations — The most realistic surgical and trauma simulations for surgeons, forward field operators, medics and medical device development.
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Rockies Venture Club
VC Fund · Denver, Colorado, United States · 10 investments in United States Medical Device startups

Connecting Entrepreneurs and Investors Since 1985.

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Investment focus

  • Industry: Software, Health Care, Medical Device
  • Stage:Seed, Series A, Convertible Note
  • Geography: United States, Canada

Investor stats

  • Total investments: 118
  • Round size: Seed $250k–$2M; Series A $1.2M–$7M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: May invest from a new fund soon — last raise in 2016

Portfolio highlights

  • MyUTI — Discover fast, reliable, easy at home testing with MyUTI. Our proven PCR testing for UTIs, BV and STIs delivers accurate results, test from the comfort of your home. Get care from home with our discreet and direct UTI lab test service.
  • Pure Blue Tech Inc. — Pure Blue Tech uses ultrasonic technology to reduce membrane fouling and can significantly lower the costs associated with membrane maintenance and replacement. The elements will allow industrial companies and municipalities to filter and purify more water, wastewater, seawater, milk, and other liquids with less money. They provide maintenance,chemicals, downtime, and waste disposal. They serving systems and plants treating.
  • Green Steel Environmental — Green Steel delivers innovative wastewater treatment solutions and plants designed for industrial sustainability, efficiency, and environmental compliance.
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The Vertical Group
VC Fund · Basking Ridge, New Jersey, United States · 10 investments in United States Medical Device startups

The Vertical Group is a New Jersey-based venture capital firm focused on the fields of medical technology and biotechnology.

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Investment focus

  • Industry: Health Care, Medical Device, Medical
  • Stage:Series B, Series C
  • Geography: United States, Israel

Investor stats

  • Total investments: 69
  • Round size: Series B $5M–$60M; Series C $1.5M–$77M
  • Lead/follow: 12% lead, 88% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2006

Portfolio highlights

  • Luminopia — Luminopia is the first FDA-approved binocular therapy for amblyopia.
  • Mobia Medical — MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas.
  • Route 92 Medical — The official website for Route 92 Medical.
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Medical Device Investor funding in United States at a glance

Stats across 5.6k deals from 4.3k investors.

4.3k
investors
in United States Medical Device startups
5.6k
deals
in United States Medical Device startups
$8.1M
median round
in United States Medical Device startups
40%
lead investors
lead at least one round
16%
Seed
most common funding stage
89/11
VC / Angel
share of investor count

Access all 4257 investors in United States Medical Device startups.

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