Top 50 Medical Device Startup Investors in United States (August 2026)

Portfolio highlights

• HerdDogg — HerdDogg is a global herd health and data science platform. It is a two-part system that helps ranchers track health and proximity data from their herd. The company's device gathers the data captured by the ear tags and reports it directly to the rancher via an app or web database.
• Insignum AgTech — Insignum AgTech develops biotech plants that communicate with producers, alerting them to an illness in its early stages.
• Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.

Portfolio highlights

• AGED Diagnostics — AGE Diagnostics develops diagnostic tools for nonalcoholic steatohepatitis (NASH, liver disease) and fibrosis (liver scarring). AGED tools can simultaneously stage fibrosis and distinguish benign from severe liver disease (liver scarring). This method measures the concentration of target biomarkers (genetic signatures) in circulation using atargeted genomic sequencing assessment. When biomarkers are detected over a specific quantity, liver disease (NASH) and/or fibrosis are diagnosed.
• Makerspace of Annapolis — Makerspace of Annapolis offers access to facilities, equipment & knowledge in the fields of robotics, manufacturing, and computer science.
• Morgan State University — Morgan State University - Maryland's Preeminent Urban Public Research University

Portfolio highlights

• Quadient Accounts Receivable by YayPay — YayPay accounts receivable automation software helps businesses collect faster, forecast cash flow accurately, and improve payment process. Automate your AR
• Sharper Sense — Neuromodulation for Clear Senses
• Willow Wealth — Willow Wealth is an alternative investment platform focused on generating income streams for investors. Get exclusive access to private market investments.

Portfolio highlights

• tbh — tbh is a developer of a mobile application designed to provide anonymous feedback to friends. The company's mobile application facilitates asking or answering questions, open text fields and invite abuse when combined with anonymity, enabling users to say things without repercussions and feel better about themselves from the positive feedbackon social networks.
• Cohley — Cohley is a content marketing platform focusing on user generated content, visual asset creation, and text review generation. Streamline your content generation today!
• Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.

Portfolio highlights

• AEENA Dx — A brilliant shift in disease detection is coming soon. Learn more A brilliant shift in disease detection is coming soon. Learn more
• Osteoboost — Bone Health Technologies specializes in developing medical devices designed for low bone mass. Its solution is a gentle mechanical stimulation that mimics weight-bearing exercise, providing an effective non-drug intervention. It offers the OsteoBoost device that relies on safe, natural, and effective whole-body vibration technology usingvibrational energy to turn stem cells into the bone using the same mechanisms as physical exercise. The company was founded in 2018 and is headquartered in San Francisco, California.
• Sandstone Diagnostics — Sandstone's Torq technology enables point-of-care clinical diagnostics and care by bringing the sample prep to the patient.

Portfolio highlights

• WINN.AI — WINN.AI helps revenue teams run better sales calls and win more deals by automating admin work and guiding reps live, during the call.
• Car Body Lab — The easy way, online.
• Perennial — Cloud Agronomics is the platform for soil carbon management.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• S2 Genomics — S2 Genomics is developing spatial sequencing technology solutions for processing solid tissues for single-cell applications. It enables automated processing of raw tissues into single cells or nuclei for genomics and cell biology studies. The company's vision is to provide products that process raw tissues into samples ready for genomicanalyses.S2 Genomics was founded in 2016 and is headquartered in Livermore, CA.
• Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
• GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.

Portfolio highlights

• Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
• TeamCentral — TeamCentral is a company focused on optimizing productivity through improvements in how data is managed and governed across business systems.
• Ravee Optics — Ravee Optics is a startup company developing ultracompact optical intersatellite links and hardware technology for high data rate communications and data transfer for small satellites and cubesats

Portfolio highlights

• Adient Medical — Medical Devices that Automatically Vanish - Adient Medical is leading the development of an absorbable vascular filter for the prevention of pulmonary embolism.
• HAYA Therapeutics — Pioneering next-generation therapies for fibrotic diseases. Learn more about our approach here.
• Viridian Therapeutics (Formerly MiRagen Therapeutics) — Committed to developing potential best-in-class medicines for people affected by Thyroid Eye Disease and other autoimmune and rare diseases.

Portfolio highlights

• Enertiv — Enertiv's is a CRE technology company that transforms building data into asset value. Top owners and operators have adopted Enertiv as their primary smart building technology and a key component in their overall PropTech strategy.
• Linebird — Linebird is revolutionizing electric transmission line maintenance by applying drone technology to a dangerous and labor intensive process.
• Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.

Portfolio highlights

• Vectra AI — Vectra AI, the cybersecurity AI company that protects modern networks from modern attacks.
• Zebra Medical Vision — NANOX AI enables more accurate risk-adjustment so patients are provided with preventative care paths they need, while improving quality of health services at significantly lower associated costs.
• Blue River Technology — Blue River Technology is a pioneer in the use of computer vision and robotics for agriculture. Founded in 2011 by two Stanford University Alumni, Blue River Technology is bringing crop protection into the digital era with See & Spray machines that precisely observe and treat each plant in a field. By applying herbicides only to weeds thesemachines dramatically reduce the amount of chemicals used, enable farmers the freedom to choose any herbicide that meets their needs, and improve grower economics. Currently, farmers are limited to equipment that applies fertilizer and chemicals inefficiently across an entire field. In contrast, Blue River have developed tractor-towed robots that are able to sense each individual plant and precisely apply the right amount of inputs – all in real time, at tractor speeds.

Portfolio highlights

• Flourish Care — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
• Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
• Vartega — Vartega is a technology development company specializing in the carbon-fiber-reinforced plastic recycling process. Vartega develops alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass-market applications.Vartega's patented carbon fiber recycling process scales rapidly to fill a gap in thecomposites supply chain. The company’s carbon fiber is available in semi-continuous, chopped, and milled forms. It is ideally suited for use in thermoplastics, non-wovens, and molding compounds.

Portfolio highlights

• Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
• Boomerang Medical — Boomerang Medical is a bioelectronic medicine company targeting autoimmune diseases.
• Pharaoh Neuro — Pharaoh Neuro develops a neurapheresis cerebrospinal fluid management system for neurological patients.

Portfolio highlights

• FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
• InnerActiv — InnerActiv is the leading NextGen eDLP solution, setting new standards in DLP, fraud and insider threat detection.
• Healia Health — Healia is a company that provides revolutionizing health insurance for dual-income households, saving employers 85% each registered family.

Portfolio highlights

• Madison Reed — Madison Reed is transforming at home hair color with ammonia free hair dye that results in multi-dimensional color that looks beautiful, healthy and natural.
• Clean Power Finance — Clean Power Finance (CPF) is building an online business-to-business marketplace to drive the mass-market adoption of solar. The company connects providers of capital who are committed to investing in residential solar with qualified solar marketers, installers and distributors who need residential solar finance products to differentiate and growtheir businesses. CPF raises 100 percent third-party‐owned project finance funds from institutional investors such as Morgan Stanley and Google, working with the investors to structure and launch the funds with managed risk and return profiles. CPF then markets the funds as solar leases and power purchase agreements (PPAs) to qualified solar professionals, including Paramount Solar and Real Goods Solar (Nasdaq: RSOL), through its licensed online solar sales platform, CPF Tools. CPF Tools is software-as-a-service that simplifies complex sales, quoting, proposal and finance processes and minimizes the “soft costs” of selling solar.CPF’s fund investors earn favorable returns on stable investments on the resulting portfolios of residential distributed generation projects. The company’s solar professional partners gain access to solar leases and power purchase agreements (PPAs) that they can brand and sell to homeowners who want the benefits of solar without the cost and hassle of owning and maintaining a system.CPF manages approximately half a billion dollars of capacity on behalf of fund investors, and supports more than 100 solar professional customers who currently use the CPF Market to sell residential solar finance products to homeowners in CA, CO, HI, MA and NJ. Thousands of solar professionals in all 50 states have extensively used CPF Tools to quote and design solar systems.
• Front Range Biosciences — Front Range Biosciences brings modern agriculture to cannabis and hemp to improve reliability, efficiency, and safety for cultivators and consumers. They provide advanced agricultural science services to plant growers.

Portfolio highlights

• Tombot — We create robotic animals that transform the daily lives of individuals, families, and communities facing health adversities. Reserve your Tombot Puppy today for FREE
• Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
• ChemT Biotechnology — The goal of ChemT Biotechnology is to increase patient access to the most cutting-edge biologics, beginning with the urgent issues in manufacturing and research and development.

Portfolio highlights

• eBrevia — Analyze contracts at scale, extract key data, and identify risk with eBrevia. Draft and redline agreements in Microsoft Word with DraftPro.
• Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
• LegiTime Technologies — LegiTime Technologies, Inc. provides LegiText, a subscription-based SMS solution that offers message authentication, categorization, and archiving based on demonstration of legitimacy technology. It also provides LegiTrac that locates and tracks devices, as well as back up and stores data in a central location; and LegiAlert that offers messagebroadcasts and alerts, creates groups and contact lists, and integrates contact information with existing back office data systems. The company serves enterprises and educational institutions, as well as consumer, finance and banking, and healthcare industries. LegiTime Technologies, Inc. was founded in 2005 and is based in Farmington, Connecticut.

Portfolio highlights

• Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
• SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
• Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Portfolio highlights

• Curb — Power your home, smarter. Curb specializes in the fields of energy engagement software and home energy management. Curb makes it possible to take control of your home's electricity use with a single product, find out what appliances and devices are driving your energy bills up. It was founded in 2012 and headquartered in Austin, Texas.
• Terecircuits — Terecircuits develops processes and materials to support microassembly and mass transfer for displays and advanced electronics.
• MatriSys Bioscience — MatriSys sees commercialization paths for its intellectual property in topical dermatology therapeutics, cosmetics, and skin care. The company’s lead live biologic therapeutic is currently in Phase I/II clinical trials targeting atopic dermatitis (commonly referred to as AD or eczema) patients.

Portfolio highlights

• Waku — Deliciously replenishing herbal tea with prebiotic powers and 0g of added sugar. Experience Sunrise on the Inside.
• HighByte — Architect your digital transformation and AI use cases with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
• Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Portfolio highlights

• Sokin — Sokin is a leading financial service provider that enables global payments for both consumers and businesses. Sokin believes in giving you the power to make payments and transfer money as many times as you want per month! Whether it’s sending money back home or transfers to friends or even settling with businesses using Sokin, our innovativeprocess makes the task quick and easy.Sokin delivers global payments for a fixed fee, is commission and hassle free!Transferring money internationally is complicated and expensive. Sometimes there is a lack of transparency in the fees you pay. With our transparent fixed monthly costs, for businesses and consumers, there are no hidden charges. You will not have to spend hours researching the best rates!Our cost effective solution is simple to understand: One Monthly Fee. This will to allow you to make payments in over 200 countries and the ability to exchange money in over 150 countries in over 35 different currencies. Sokin can also transfer any currency into any bank account in China within 2 hours excluding weekends and Chinese bank holidays.To find out more about the only payment provider to provide global payments for a fixed fee, commission free and hassle free – download our app and sign up to ensure you don’t miss out on key messages!
• Inhibrx — Inhibrx is a clinical-stage biotechnology company focused on developing a broad pipeline of novel biologic therapeutic candidates. Inhibrx utilizes diverse methods of protein engineering to address the specific requirements of complex target and disease biology, including its proprietary sdAb platform. The Inhibrx pipeline is focused on oncology,orphan diseases, and infectious diseases. Inhibrx has collaborations with Celgene and Bluebird Bio and has received awards from several granting agencies, including NIH, NIAID, and CARB-X.
• Vortexa — State of the art energy analytics that paints a global picture of cargo flows. Identify energy market opportunities before the competition with Vortexa.

Portfolio highlights

• MiClient — Miclient are deal closure platform which was founded by experienced sales leaders who recognized the need for a new generation of complicated quote configuration, contract signing, renewal & payment collection at one place for SMEs, Lead Management System, B2B SaaS, CRM software, CPQ (Configure- Price- Quote)
• Healionics — Healionics aims to provide safer, more reliable means of bloodstream access for dialysis in patients with kidney failure.
• NuvOx Therapeutics — NuvOx Pharma is a clinical stage biotech company developing an innovative platform of oxygen therapeutics to treat life-threatening diseases where hypoxia plays a role.

Portfolio highlights

• Ognomy Sleep — Are you looking for a sleep apnea app? Ognomy brings the high-quality care you can expect from an online sleep doctor. Our mission is to improve global health by democratizing access to care for those who suffer from sleep apnea - over 1 billion people worldwide.
• Bridge Green Upcycle — Bridge Green Upcycle is a clean energy company that specializes in lithium-ion battery upcycling technology solutions.
• Casana — Casana is unlocking a new category in healthcare technologies that enable effortless, integrated and consistent in-home heart health monitoring. Casana’s first product, The Heart Seat™ is an IoT heart health toilet seat that captures clinically relevant measurements, including heart rate, blood pressure, blood oxygenation, and cardiac output.Casana’s mission is to assist medical teams in their care management of patients with chronic conditions beyond the four walls of the hospital, starting with the 6M+ people in the US living with Heart Failure.

Portfolio highlights

• RenovoRx — RenovoRx is a developing innovative solutions for targeted delivery of fluids, including diagnostic and therapeutic agents, to selected sites in the peripheral vascular system. RenovoRx received FDA clearance for the RenovoCath™ RC120 and is currently introducing this innovative technology to the clinical market.RenovoRx has a motivatedManagement Team with broad experience and an exciting vision for the future of targeted delivery. The company also has a broad Advisory Board of interventional radiologists, surgical oncologists and gastroenterologists that guide the company's clinical development strategies. RenovoRx is backed by a strong Board of Directors committed to long-term, continuous support of the company, whose members provide critical expertise in the medical and biotechnology industry and the visionary thinking to succeed.
• ColorModules — ColorModules is an early stage start-up which has created a patent-pending search technology that recommends products to consumers based on "visual" characteristics and preferences, such as color. ColorModules sets out to alleviate the common shopping frustration of searching dozens or hundreds of items to find the right product.Currently, ColorModules focuses on the visually-driven beauty, fashion, and home décor industries.Its first website, PlumPerfect.com, is for beauty shoppers. Users can take and upload a photo, and the service recommends for them colors and products.
• Style for Hire — Style for Hire is a national network of trained and certified personal stylists who bring affordable in-home wardrobe advice and shopping assistance to customers. Celebrity stylist Stacy London, from TLC's What Not to Wear, is co-founder, spokesperson, and Stylist-in-Chief.

Portfolio highlights

• Ossio — OSSIO is an orthopedic fixation company committed to transforming the orthopedic experience for patients, physicians, and payors. Their vision is to provide the first credible replacement to metal implants in the $10B+ orthopedic fixation market (screws, pins, plates) with an Intelligent Bone Regeneration Technology. OSSIOfiber represents abreakthrough material platform for orthopedic and podiatric surgeons who seek a more biologically friendly way to restore patient stability and mobility with nothing permanent left behind.Founded in 2014, OSSIO began as the culmination of years of biomechanical research and a vision for the possibility of better bone healing. The technological basis of OSSIOfiber™ was developed and would lay the groundwork for ushering in a new breakthrough category of non-permanent fixation, “Bio-Integratives” hardware that has both desired strength AND bio-friendliness. Hardware that has the mechanical strength for easy insertion and secure fixation, while enabling the body to regrow bone, incorporating and replacing the implant (without the adverse inflammation and weakness often seen in “bio-resorbables and other “bio-composites”), has remained elusive to the industry until now.
• Stellar Cyber — Stellar Cyber: Automation-Driven, Open & Unified SecOps Platform with AI SIEM, NDR, Open XDR, and Multi-Layer AI.
• Hyperfine — Hyperfine makes MRI accessible to every patient regardless of income or resources.

Portfolio highlights

• Gelmedix — Gelmedix is a developer of a biomaterial platform to improve drug delivery for complicated ophthalmic treatment. The company's platform offers a single non-invasive gel patch that can be used as a drug-eluting sealant with tissue adhesion, tunable drug elution, and biocompatibility properties, thereby enabling healthcare providers to reducethe usage of drops which cause inconvenience to patients.
• Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
• Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Portfolio highlights

• ATDev — ATDev builds robotic mobility and assistive technology for elderly and disabled people, from the RAMMP mobility platform to the Reflex rehab knee brace.
• Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
• Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.

Portfolio highlights

• Obsidio — Obsidio™ Conformable Embolic with aqueous gel technology is a 510(k) cleared device, the first of its kind to have a specific on-label indication for peripheral use in the U.S.
• Skyhawk Therapeutics — Skyhawk Therapeutics is a clinical-stage biotechnology company focused on the discovery and development of novel small molecule therapies designed to modulate critical RNA targets and revolutionize patient treatment for some of the world's most intractable diseases.
• Osteoboost — Bone Health Technologies specializes in developing medical devices designed for low bone mass. Its solution is a gentle mechanical stimulation that mimics weight-bearing exercise, providing an effective non-drug intervention. It offers the OsteoBoost device that relies on safe, natural, and effective whole-body vibration technology usingvibrational energy to turn stem cells into the bone using the same mechanisms as physical exercise. The company was founded in 2018 and is headquartered in San Francisco, California.

Portfolio highlights

• CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
• Aigensei — Aigensei.ai develops artificial intelligence software and infrastructure tools that support the creation, deployment, and management of AI applications. Its work includes systems for workflow automation, model integration, and operational use of AI across different computing environments and application domains.
• LoanStar Technologies — LoanStar works with lenders to diversify their consumer loan origination strategies. Providing program consulting, market-leading software, and merchant aggregation, LoanStar helps lenders of every size leverage the power of their local brand.LoanStar has developed the MerchantLinQ platform that enables lenders of all sizes to deploy instantpoint-of-sale finance through their local merchants.

Portfolio highlights

• Graphite Bio — Graphite Bio is a next-generation gene editing company focused on therapies that harness targeted gene integration to treat or cure serious diseases
• Dayra Therapeutics — Dayra Therapeutics manufactures peptide based medicines.
• Jecure Therapeutics — Jecure Therapeutics is focused on the discovery of innovative therapeutics for the treatment of non-alcoholic steatohepatitis.

Portfolio highlights

• Lena Health — Lena is a virtual health assistant that takes care of all tasks to stay on top of the care plan, so you can sit back and focus on the things that matter to you.
• Epitel — Epilog is an unobtrusive wearable seizure detection system that records long-term EEG, anywhere. It gives people living with epilepsy peace of mind with a much-needed tool to better understand and manage their seizures.
• Rejoni — Rejoni uses bio-materials to develop medical devices that improve the outcome of minimally invasive and gynecological surgical procedures.

Portfolio highlights

• Ribometrix — The Next Frontier of Drug Discovery
• G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.
• Viamet Pharmaceuticals — Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allowsthem to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.

Portfolio highlights

• Donna — Meet Donna, the AI assistant built for field sales teams. Save time, cut admin, and close more deals with less effort.
• Suma Wealth — Meet Charlie, your AI financial coach inside the SUMA app. Get personalized budgeting, savings, and investing advice in English or Spanish.
• Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.

Portfolio highlights

• DropCap — International Rights Platform for Books | DropCap
• Cylerity — Transform healthcare receivables into real-time capital. Cylerity unlocks cash flow, clarity, and control from claims data. See how it works.
• Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Portfolio highlights

• QMENTA — Our industry-leading neuroimaging cloud-based software works with advanced AI-powered tools to empower researchers, radiologists, and clinical trials.
• Handl Health — Making healthcare price transparency simple, insightful and actionable.
• Ventaris Surgical — Ventaris Surgical is a medical equipment company that provides surgical instruments to specialists.

Portfolio highlights

• LineWise — LineWise, a Y Combinator-backed startup, helps manufacturers maximize production uptime. We use AI to diagnose machine failures, accelerate troubleshooting
• Spectrohm — Spectrohm is the next generation of internal imaging.
• Autonomous Cyber — Autonomous Cyber is an artificial intelligence platform for cybersecurity solutions.

Portfolio highlights

• FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
• InnerActiv — InnerActiv is the leading NextGen eDLP solution, setting new standards in DLP, fraud and insider threat detection.
• Niobium Microsystems — The encrypted cloud has arrived.

Portfolio highlights

• SyntaxBio — SyntaxBio develops CRISPR/Cas9-based, genetic programming platform that converts cells into biological computers using DNA-based instructions that read like lines of code. SyntaxBio's platform can program cells without the need for consistent external intervention.
• ElectroKare — Train like the 1%. Electrokare turns wearables into a real-time coaching layer, with electrolyte tracking, ECG integration, and AI-driven performance insights built for elite training.
• Transcripta Bio — Drug discovery at the resolution of biology. Using the power of the transcriptome to discover revolutionary medicines.

Portfolio highlights

• Nervonik — Explore Nervonik neuromodulation devices that are working to redefine peripheral nerve stimulation with advanced technology for high motion.
• Cagent Vascular — Cagent Vascular pioneers Serration Remodeling Therapy (SRT) creating controlled lines of weakness to release the internal elastic lamina, reducing recoil and increasing luminal gain in PAD angioplasty.
• Maneva — Maneva Copilot AI is able to interpret, summarize, and combine the diverse landscape of data that exists throughout your production facility, and deliver the appropriate content to the question provided at all levels of roles, whether it is operational supervisors, quality managers, and management, process engineers, or maintenance leads

Portfolio highlights

• Bliss — Skip long waitlists and expensive therapy. Book licensed online therapists in multiple languages with culturally informed care.
• BatteryPool — BatteryPool offers battery charging solutions for EV fleets and commercial vehicles.
• Apriority Financial — Apriority Financial is a debt optimization platform that manages and optimizes employee personal debt.

Portfolio highlights

• Peptyde Bio — Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.
• SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
• Maximum Fidelity Surgical Simulations — The most realistic surgical and trauma simulations for surgeons, forward field operators, medics and medical device development.

Portfolio highlights

• Synthesia — Create AI videos by simply typing in text. Make engaging videos for e-learning, customer onboarding, etc. No need for actors, cameras or audio equipment.
• Biz AI Last — Are you ready to elevate your business efficiency and productivity? Say hello to Biz AI, your intelligent business assistant designed to streamline operations, boost productivity, and give you more time to focus on what matters most – growing your business.
• Hippocratic AI — The First Safety Focused LLM for Healthcare

Portfolio highlights

• Nervonik — Explore Nervonik neuromodulation devices that are working to redefine peripheral nerve stimulation with advanced technology for high motion.
• Sound Health — Sound Health uses acoustic resonance to provide nasal relief. Its current product is an app that scans the face to map the bone structure and then a headband that plays music at personalized frequencies for 10 minutes. The headband is off the shelf and the sound levels are akin to wearing earpods. It envisions the headband to be over-the-counter(OTC) so it’s easily accessible to patients, whether prescribed by doctors or not.
• Sound Health & Wellness Center — The Sound Health & Wellness Trust is a Taft-Hartley trust managed jointly by unions and employers and providing benefits to more than 51,000 participants.

Portfolio highlights

• ITeam — iTeam is transforming the way information technology (IT) and audio/video (A/V) installation services are packaged, sold and delivered through a new approach called Service-as-a-Product™ (SaaP™).
• Fusion Mobile — Fusion Mobile is a prepaid wireless company focused on the Hispanic population in the Southwestern U.S.
• Organ Transport Systems — Time-critical organ transport needs one operating view.

Portfolio highlights

• Vellum Health — Vellum Health platform provides on-demand IV enablement & treatment optimized for provider organizations, payers, clinicians, and patients.
• Affineon Health — Affineon is the AI inbox that saves provider time. We automatically handle normal and clinically insignificant lab results, and help providers get through abnormal lab results faster. Our AI automatically groups, analyzes, and trends lab results into a smart summary, including possible next steps and a complete patient note. We also route"noise" to staff, reducing the number of messages a physician needs to pay attention to by up to 30%. The result is 5+ hours saved per week per provider. Plus, Affineon tightly integrates with the EHR, so providers don’t need to change their existing workflow.
• Mobia Medical — MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas.

Portfolio highlights

• Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
• NinePoint Medical — NinePoint Medical, Inc. is a transformational medical device company developing innovative, real-time, in vivo pathology devices. The company's first goal is to develop a device that enables remote pathology, or telepathology, which would facilitate immediate review of images during diagnostic procedures. This capability could potentiallyprovide physicians with immediately actionable information and eventually allow them to pursue therapeutic remedies at the time of diagnosis. This convergence of access, diagnosis and treatment during one procedure is expected to improve patient experiences and outcomes, improve the efficiency of care and provide important savings to the healthcare system. Headquartered in Cambridge, Mass., NinePoint is backed by Third Rock Ventures and Prospect Venture Partners.
• CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.

Portfolio highlights

• SeeQC — SEEQC is developing the first digital quantum computing platform for businesses. SEEQC combines classical & quantum technologies to address the efficiency, stability & cost issues endemic to quantum computing.
• Outcomes4Me — Outcomes4Me is empowering cancer patients globally with treatment options, medical records, and clinical trials all in one app.
• Autonomize AI — Transform healthcare with our innovative Healthcare AI platform that enhances workflows and boosts efficiency.

Portfolio highlights

• Aseon Labs — Robotic pitstops for self driving cars. A depot in a box for charging, cleaning & inspecting AVs directly in operating zones. Backed by @ycombinator
• Cooler Heads — Cooler Heads develops cold caps designed for chemotherapy patients.
• Surface Design Solutions — Surface Design Solutions uses physics-informed AI to help manufacturers reduce scrap, improve yield, and diagnose costly surface performance issues.

Portfolio highlights

• Luminopia — Luminopia is the first FDA-approved binocular therapy for amblyopia.
• Mobia Medical — MicroTransponder is a medical device company that develops and commercializes neurostimulation devices to treat neurological diseases. Its therapies include paired vagus nerve stimulation system (Paired VNS System) and wireless neurostimulation system for the treatment of chronic pain, post-stroke upper limb mobility issues, and variousneurological indications that enable healthcare practitioners to treat post-stroke upper limb mobility issues.Founded in 2007, MicroTransponder is headquartered in Dallas, Texas.
• Route 92 Medical — The official website for Route 92 Medical.