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Top 50 Medical Startup Investors in United States in July 2025

Last updated: Jul 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Medical startups based in United states. We rank investors based on the number of investments they made in Medical companies from United states. We update this investor list every month.

Top 50 Medical Startup Investors in United States in July 2025

Investor	Medical United States investments
Innova Memphis	58
ARCH Venture Partners	39
SOSV	37
New Enterprise Associates	37
Polaris Partners	32
Connecticut Innovations	30
Third Rock Ventures	28
Alumni Ventures	28
F-Prime	28
Canaan Partners	27
OrbiMed	27
Atlas Venture	27
Wavemaker 360	26
Wisconsin Investment Partners	26
Alexandria Venture Investments	25
BioAdvance	25
Rock Health Capital	25
Versant Ventures	23
KdT Ventures	23
Green Park & Golf Ventures	23
Lux Capital	22
MB Venture Partners	22
General Catalyst	22
Gaingels	21
Khosla Ventures	21
Houston Angel Network	21
TEDCO	20
The Column Group	20
Asset Management Ventures (AMV)	20
8VC	20
Domain Associates	20
Google Ventures	20
SpringTide Ventures	19
Andreessen Horowitz	19
Martin Ventures	19
Right Side Capital Management	18
Sante Ventures	18
Sanofi Ventures	18
Founders Fund	18
Portfolia	18
First Round Capital	17
StartUp Health	17
Venrock	17
MPM Capital	17
Omega Funds	17
Hatteras Venture Partners	17
RA Capital Management	17
Square 1 Bank	16
Maverick Ventures	16
True Ventures	16

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Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, China, United Kingdom

Portfolio highlights

Rhygaze — Rhygaze develops a novel gene therapy that targets cone cells to restore vision in patients suffering from diseases causing blindness.
Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Atlas Data Storage — Atlas Data Storage develops data storage systems utilizing synthetic DNA to encode digital information. The company offers end-to-end solutions that integrate semiconductor-based synthesis and enzyme engineering to store data in DNA strands. This approach aims to provide long-term, high-density storage options for various sectors. Atlas DataStorage's technology is designed to address the growing demand for scalable and energy-efficient data storage solutions.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Series C
United States, India, Canada

Portfolio highlights

NG.CASH — NG.CASH is a digital app designed to help Generation Z become financially independent. It allows users to manage their own money with solutions such as PIX (Brazil’s “instant-payment” method), prepaid credit card, allowance management and a virtual card, in addition to features that let users customise the app’s design and a marketplace withdiscounts on Gen Z’s most desired brands. Structured as a financial hub, NG.CASH aims to accompany its clients throughout their lives and increase financial literacy in the region.
Wispr Flow — Wispr AI is a developer of the next-generation of neural interfaces to provide seamless interface with immersive technology. The company is working with the leading neuroscientist, hardware engineers, machine learning researchers, and product engineers to bring frontier technology to the mass consumer market.
Spyglass Pharma — Spyglass Pharma focuses on the development of novel treatments for chronic ophthalmic diseases based on technology. The company designs to deliver multiple drugs to address additional ophthalmic indications.

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Ireland, Singapore

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
Leyden Labs — Leyden Labs helps people live freely by developing products that protect from known and new respiratory viruses.
Auron Therapeutics — A differentiated approach to cure cancer.

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
VeraDermics — VeraDermics Inc. is a dermatology pharmaceutical start-up, makers of WartPatch
PHȲND — PHȲND is a subscription-free cloud gaming platform that offers a way to discover, play, and socialize across a wide variety of games.

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

Alumni Ventures Group provides high-quality, diversified venture portfolios to individual investors who previously haven't had access to VC.It helps accredited alums from top entrepreneurial schools invest together in the ventures of fellow alums. The firm backs companies with an alumni connection and an institutional lead investor withexpertise in the space. AVG also offers focused funds that allow any accredited investor access to a venture portfolio, diversified by type, sector, stage, and geography.Beth Obermiller, Michael Madden, and Mike Collins co-founded the firm in Manchester, New Hampshire in 2013.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Definely — Definely creates legal tech solutions to free lawyers from frustration, saving them time when understanding, drafting and reviewing legal documents.
Kognitos — Kognitos is in stealth mode.
CRED — Compare millions of commercial data points and uncover unique and personalised opportunities for your brand.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

Dinari — Discover Equity Boundless - Simplify everything from equity management and options grant to payroll so that you no longer have to worry about compliance, taxes, or vesting schedules no matter where your employees are.
Dataplor — Leveraging machine learning, AI, and human capital, dataplor delivers verified international places data to the world's leading companies.
Canary Technologies — Use Canary to securely conduct contactless check-in and process credit card authorizations, contracts, and amenities online. Canary is the only PCI Level-1 Compliant solution for hotel authorizations. Schedule a demo today, and see how we can help your properties reduce chargebacks, save time, and improve the guest experience.

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, United Kingdom, Israel

Portfolio highlights

Actio Biosciences — At Actio, we are leveraging advances in genetics and precision medicine to develop life-changing treatments that target underlying shared biology between rare and common diseases. We are applying expertise in genetics, drug discovery, and data sciences to pinpoint targets that not only cause rare diseases with high unmet need, but that also hold promise in more common indications.
Vima Therapeutics — There are over 1 million people with dystonia and related movement disorders in the US and over 100,000 people with isolated dystonia.
Draig Therapeutics — Draig Therapeutics is a clinical-stage biopharmaceutical startup dedicated to creating next-generation treatments for serious neuropsychiatric illnesses.

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

Renasant Bio — Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.
Alpheus Medical — Our Brain Cancer Clinical Trial is investigating Sonodynamic Therapy. A painless, non-invasive ultrasonic technology for the treatment of glioblastoma.
CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Renasant Bio — Renasant Bio is a biopharmaceutical company pioneering disease-modifying oral small molecule treatments.
Vima Therapeutics — There are over 1 million people with dystonia and related movement disorders in the US and over 100,000 people with isolated dystonia.

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

DropCap — We are an innovative foreign rights literary agency that elevates exceptional books to the worldwide stage.
Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Canada, France

Portfolio highlights

Remedy Plan Therapeutics — Remedy Plan is a biotechnology company developing the first drugs that halt tumor growth and disrupt the cancer stem cells that cause metastasis.
HAYA Therapeutics — Pioneering next-generation therapies for fibrotic diseases. Learn more about our approach here.
GeneCentric Therapeutics — GeneCentric Therapeutics engages in developing and commercializing molecular diagnostic tests for oncologists and patients. The company currently has two unique platform technologies including The Lung Subtype Platform (LSP) stratifies lung cancer patients into subtypes, which are important for appropriate therapeutic selection. The firstapplication of LSP was licensed to and independently developed by Laboratory Corporation of America Holdings (“LabCorp”) and is now available through its specialty testing business, Integrated Oncology, as HistoPlusSM: Lung Cancer. Its second platform technology is the Hypoxia Signature which has the potential to identify patients that respond to anti-angiogenesis therapies.GeneCentric utilizes a unique partnership model to translate important cancer discoveries into clinically adopted diagnostics for pathologists, clinicians, and, most importantly, patients. The company was incorporated in 2011 and is based in Durham, North Carolina.

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

Investment focus

Biotechnology, Health Care, Medical
Seed, Funding Round, Series A
United States, Canada

Portfolio highlights

KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies. they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.

We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.

Investment focus

Health Care, Software, Medical
Seed, Series A, Series B
United States, Denmark

Portfolio highlights

Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

Granite Bio — Targeting fundamentals of Inflammation, Autoimmunity and Fibrosis. Granite Bio develops first-in-class therapeutic antibodies depleting pathogenic cells with the potential to transform inflammatory and fibrotic diseases.
Helicore Biopharma — Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders.
Light Horse Therapeutics — Light Horse Therapeutics is the gene editing applied to small-molecule drug discovery, pioneering approaches to target the root causes of disabling and life-threatening diseases. Its advanced platform identifies cryptic chemically accessible functional domains within targets that are critical in disease biology. Our initial focus addresseshigh-value, historically challenging oncology targets with the opportunity to apply the technology to other therapeutic areas in the future.

KdT Ventures is the standard for early-stage frontier science investing.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Israel, Germany

Portfolio highlights

Shiprocket — Shiprocket is India's most-used eCommerce logistics and shipping software solution for the best courier services. Avail features like COD (Cash on Delivery), prepaid delivery, automated shipping, etc.
March Biosciences — Transforming Patient Care by Unlocking New Target Spaces March Biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity
Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases

Green Park & Golf, built on over 50 years of operational and financial experience, seeks investment opportunities that offer above-market returns for its investors. Led by Clay Heighten, M.D., and Carl Soderstrom, the Firm delivers strategic solutions, financial backing and a reliable network to its portfolio companies. The Dallas-based Firm iscurrently looking for investment opportunities in medical-related start-ups.Dr. Heighten founded MedicalEdge Healthcare Group in 1993, and Mr. Soderstrom started PhyServe Physician Services in 1998 to administer the financial and operational needs of MedicalEdge. Together, the companies managed over 550 providers in five major markets. In 2011, the companies were sold to Texas Health Resources, a $3.8 billion health care system. That’s when Green Park & Golf was born.After earning his MBA at Southern Methodist University, Mr. Garcia joined them full-time in May 2011 to actively pursue new investment opportunities and monitor other investments in their portfolio. He has prior professional experience at FedEx, Bold Ventures, and Lone Star Investment Advisors.

Investment focus

Health Care, Medical, Biotechnology
Series A, Seed, Series B
United States, Israel, Sweden

Portfolio highlights

Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
Vellum Health — Vellum Health platform provides on-demand IV enablement & treatment optimized for provider organizations, payers, clinicians, and patients.
Affineon Health — Affineon is the AI inbox that saves provider time. We automatically handle normal and clinically insignificant lab results, and help providers get through abnormal lab results faster. Our AI automatically groups, analyzes, and trends lab results into a smart summary, including possible next steps and a complete patient note. We also route"noise" to staff, reducing the number of messages a physician needs to pay attention to by up to 30%. The result is 5+ hours saved per week per provider. Plus, Affineon tightly integrates with the EHR, so providers don’t need to change their existing workflow.

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Armada — The Armada Platform is a whole new way to succeed at the Edge with Starlink connectivity, mobile data centers & AI. Schedule a demo today.
Varda — Expanding the economic bounds of humankind with the world's first orbital manufacturing & reentry platform.
Hadrian — We are building the planet's most efficient factory to accelerate a democratic, abundant, spacefaring future.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Investing in powerful, positive change that endures

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, India

Portfolio highlights

Certify — CertifyOS is an API-first, UI agnostic, end-to-end provider network management platform for credentialing, monitoring, licensing, provider health plan enrollment, and provider sourcing. With integrations into 100’s of primary sources, enabling near real-time verification and credentialing for enrollment, CertifyOS is uniquely positioned to be theone-stop shop for all provider networking needs, including provider sourcing, licensing, credentialing, health plan enrollment, and ongoing monitoring.
Raphe mPhibr — Raphe mPhibr is an aviation and aerospace component manufacturing that designed and manufacturing comprehensive.
Bilt Rewards — Bilt is the payments and rewards program for where you live, transforming rent payments into valuable rewards while connecting members with exclusive benefits in their neighborhood.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

Nava — Nava Benefits is a modern employee benefits brokerage leveraging technology and benefits innovation to tackle the rising costs of healthcare.
Akash Systems — Akash is a pioneer in thermal management, offering solutions that set the global standard for technology.
Galileo — Galileo provides high-touch, data-driven, multi-specialty, longitudinal care to a diverse and complex patient population—over the phone, at home, and everywhere in between. Regional and national health plans, employers, and Fortune 500 companies all regard Galileo as the leading solution for improving population health. It aims to use that talentand scientific thinking to transform society by solving the most difficult healthcare problems while also bringing patients and providers closer together.

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Varda — Expanding the economic bounds of humankind with the world's first orbital manufacturing & reentry platform.
Hertha Metals — Sustainable Steel Manufacturing is the future. At Hertha Metals, we develop eco-friendly steel solutions to drive a greener industry.
Moonvalley — a research lab focused on pushing the frontiers of creativity through deep learning.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

Investment focus

Health Care, Software, Biotechnology
Seed, Pre-Seed, Grant
United States, Canada, United Kingdom

Portfolio highlights

Atme — Atme is designed to let drivers communicate quickly, safely, and anonymously using license plate messages.
Keep Company — Keep Company is a coaching community for parents & caregivers.
Astek Diagnostics — Saving lives through antibiotic sensitivity precision diagnostics

The Column Group (TCG) is a venture ecosystem dedicated to fueling scientific innovation in the life sciences industry.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

A2 Biotherapeutics — A2 is dedicated to advancing cancer treatment through pioneering cell therapy. Our T cells target solid tumors with precision, transforming the future of medicine.
Eikon Therapeutics — Eikon Therapeutics is a drug discovery and development company that leverages super-resolution microscopy as well as the latest advances in biology, chemistry, engineering, and automation toward the goal of discovering and inventing innovative therapies that will improve and extend life.
Neurona Therapeutics — Neurona Therapeutics is a pre-clinical stage biotechnology company that was founded by four neuroscientists and stem cell pioneers at The University of California, San Francisco. They are focused on the discovery and development of cell-based therapies to treat intractable neurological disease. Its initial aim is to generate therapeuticcompositions of a specific type of nerve cell (or neuron) for targeted delivery into the injured nervous system. Based on nearly two decades of research, they believe that particular subpopulations of neurons have the unique ability to integrate and repair dysregulated neural circuits. Its talented team of scientists, scientific advisors, and board directors is working to accelerate breakthrough treatments for patients with significant unmet medical needs.

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

Investment focus

Health Care, Biotechnology, Software
Series A, Seed, Series B
United States, Cyprus, Ireland

Portfolio highlights

basys.ai — Reducing administrative burden in healthcare through secure, interpretable, and adaptive AI workflows. AI-Powered Prior Auth & Provider Workflow Automation. Streamline prior authorization with Basys AI-driven UMAI solutions for provider workflow automation. Ideal for health plans, RFPs, and digital transformation.
Autonomize AI — AI Copilots for Healthcare & Life Sciences. Empower knowledge workers, reduce administrative burden and improve health outcomes.
Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Memebox — Memebox Corporation is a consumer company that provides customers with the Asian beauty products, culture, and trends. A global company focused on forecasting trends and creating private, in-house labels inspired by K-beauty (and made for the product obsessed).
Portal Biotech — Portal has created next generation solutions that address the significant opportunities in protein sequencing and metabolomics
Bedrock Robotics — Bedrock Robotics delivers enhanced autonomy to the built environment, allowing the construction sector to build at the rate that today's society requires.

INVESTMENT ADVISORS TO THE FIRST VC FUND DEDICATED TO BIOTECH INVESTMENT MANAGER OF 9 SUBSEQUENT BIOTECH VC FUNDS

Investment focus

Biotechnology, Health Care, Medical
Series B, Series C, Series A
United States, Canada, Estonia

Portfolio highlights

Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.

GV supports innovative founders moving the world forward.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Seed
United States, United Kingdom, Switzerland

Portfolio highlights

PostHog — PostHog is the only all-in-one platform for product analytics, feature flags, session replays, experiments, and surveys that's built for developers.
OpenEvidence — OpenEvidence uses artificial intelligence to aggregate, synthesize, and visualize clinical evidence in understandable, clinically-useful formats that can be used to make more evidenced-based decisions and improve patient outcomes.
Glass Imaging — Traditional cameras rely on an imaging lens which typically consists of several lens elements and a light sensitive sensor. Cameras have been built like this since 1816. Glass has been historically used to make high quality optical elements. We are replacing these elements with deep neural networks that give extreme flexibility when designing ourcameras. It allows us to squeeze a huge sensor into an ultra thin module that fits perfectly into a mobile device without the need for protruding bumps. Our cameras bring SLR image quality into your pocket.

SpringTide is a venture capital that provides investment in the health tech industry. The firm was founded in 2018 and is headquartered in Cambridge, Massachusetts, United States.

Investment focus

Health Care, Medical, Software
Seed, Series A, Funding Round
United States, Israel

Portfolio highlights

Nest Health — Nest Health is a primary care company that offers whole person, whole family care for families from birth through age five in urban areas. Nest offers primary and pediatric care for families, made affordable and convenient.
Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.
Paterna Biosciences — Male infertility care is lagging. Paterna is changing that with in vitro spermatogenesis. Explore our science and meet the team.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

OpenRouter — OpenRouter is a platform that connects AI applications with large language models and cloud hosting providers, allowing users to optimize for costs, speed, and performance. The platform supports over 180 AI models, offers a unified API, and includes functionalities like private chat and exploratory data capabilities. OpenRouter sets the newbenchmark for large-scale AI inference with its global edge infrastructure, privacy-focused design, real-time accounting, and integrated billing.
Shield USDT — Shield is the first B2B cryptocurrency exchange designed for international businesses. Access a US-based virtual bank account to buy, sell, and transfer crypto.
Abridge — For patients, clinicians, and enterprise, our audio-based solutions capture the details and summarize medical conversations, anywhere care happens.

Martin Ventures provides capital, operational support and mentoring to assist entrepreneurs who want to be catalysts for change. Focusing primarily on health care and technology initiatives, Martin Ventures’ unique approach allows the leadership of our portfolio companies to more acutely focus on the optimal execution of their vision and strategywhile quickly scaling and growing their businesses into successful, profitable organizations.

Investment focus

Health Care, Medical, Hospital
Series A, Seed, Funding Round
United States

Portfolio highlights

BEKHealth — BEKhealth connects sites and sponsors with AI-powered solutions to find and match patients to clinical studies.
ArcheHealth — ArcheHealth is enabling hospitals to operate more efficiently, cut expenses, and maintain expansion.
Peregrine Health — Peregrine Health provides the most comprehensive health care solution for underserved communities. We empower clinics to improve patient outcomes. Find out how.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
Eachlabs — AI marketplace for developers.
Hutsy — Hutsy Financial is a financial services company that provides mobile banking, early payroll access and credit building products. In partnership with Peoples Trust we provide a prepaid debit card that our users can spend with. We also offer cash back on all purchases, spending insights, and categorizations to provide valuable insight on where yourmoney is going. Hutsy was recently on CBC’s Dragons Den where we raised our pre-seed funding round of $500,000 to bring our product to life.

Privately Held Companies

Investment focus

Health Care, Medical, Biotechnology
Series A, Series B, Series C
United States, Canada, Australia

Portfolio highlights

Graici — Meet Graici, Adaptive Engagement Technology delivering at the speed of need to power positive outcomes for individuals and institutions.
Ten Bay Bio — Ten Bay Bio is a biotechnology company that offers biological therapies for treatment of complex diseases in immunology.
Solu Therapeutics — Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells.

Sanofi Ventures invests in top tier biotherapeutic and digital health entrepreneurs who focus on helping patients and transforming the healthcare system.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, United Kingdom, France

Portfolio highlights

Therini Bio — Therini Bio is developing novel therapeutics based insights into the role of fibrin in driving chronic innate immune activation.
Splice Bio — Splice Bio is a gene therapy company based on technology developed in the Muir Lab at Princeton University. The company is developing novel gene therapies based on its proprietary intein platform technology to treat patients that suffer from incurable genetic diseases. The company’s platform has the potential to address two existing limitations ofadeno-associated viruses (AAVs), both by increasing the size of the cargo gene that can be delivered and by expanding the range of tissues that can be targeted.
Draig Therapeutics — Draig Therapeutics is a clinical-stage biopharmaceutical startup dedicated to creating next-generation treatments for serious neuropsychiatric illnesses.

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Armada — The Armada Platform is a whole new way to succeed at the Edge with Starlink connectivity, mobile data centers & AI. Schedule a demo today.
Varda — Expanding the economic bounds of humankind with the world's first orbital manufacturing & reentry platform.
Bitmine Immersion Technologies — Bitmine Immersion Technologies engages in bitcoin mining and hosting.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Software, Biotechnology
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and
Zero Point Five Therapeutics — A drug development company treating soil transmitted helminthiasis (STH) through the FDA as a single dose formulation. STH is a disease impacting poor rural communities of color with poor sewage systems.

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

Investment focus

Software, Information Technology, E-Commerce
Seed, Series A, Series B
United States, Canada, India

Portfolio highlights

Andrenam — Andrenam is building an AI-powered, distributed maritime sensing network for persistent autonomous awareness from surface to seabed.
Solidroad — Increase CSAT without increasing cost with the AI QA & training platform that reviews 100% of your customer conversations. Generate individualized training simulations for human reps and refinement recommendations for AI agents.
arketa — Online and in-person classes, video on-demand, courses and website hosting - all in one platform with arketa.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
JETSWEAT — Jetsweat is a well-being platform that helps organizations engage populations to live healthier lives. We partner with forward-thinking employers, health plans and health systems to set a new standard for holistic and preventative care, driving better outcomes through engaging journeys, personalized programming from exclusive provider ecosystem,and dedicated white-label software.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Building Companies that Shape the Future

Investment focus

Health Care, Biotechnology, Software
Series B, Series A, Series C
United States, Canada, Switzerland

Portfolio highlights

Oumi — Building truly open, reliable frontier AI.
Suki — Suki is an AI-powered voice assistant that lifts the administrative burden from clinicians, so they have time to focus on what matters - patient care.
GenLogs — Get ready to have your operations supercharged! Our real-time data on all trucks in America helps you find the right capacity at the right time.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series A, Series B, Series C
United States, Canada, United Kingdom

Portfolio highlights

āshibio — āshibio creates treatments for rare bone and connective tissue ailments, potentially preventing symptoms or slowing their course.
Umoja Biopharma — Pioneering immunotherapy by reprogramming T cells in vivo to target cancer cells.
Reunion Neuroscience — Reunion Neuroscience is a clinical-stage pharmaceutical company developing therapeutic solutions for underserved mental health conditions. The Company’s lead asset, RE104, is a proprietary, novel serotonergic psychedelic compound being developed as a potential fast-acting and durable antidepressant for patients suffering from postpartum depressionand other mental health conditions. Reunion is also developing the RE200 series, which includes compounds with the potential for more selective serotonin receptor activity and reduced psychoactivity for application in more chronic treatment paradigms and indications.

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Switzerland, United Kingdom

Portfolio highlights

Windward Bio — Windward Bio is a clinical-stage drug development company focused on improving outcomes for individuals with advanced immunological diseases, particularly severe respiratory conditions. The company is advancing a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP) into phase 2 development while creating innovative bispecific programsfor various immunological disorders. Led by a team of biopharmaceutical executives, Windward Bio aims to address significant unmet medical needs in this field.
Alleviant Medical — Interventional therapy for congestive heart failure
Callio Therapeutics — Callio Therapeutics focuses on developing next-generation, multi-payload antibody-drug conjugates to maximize therapeutic benefits.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Canada

Portfolio highlights

410 Medical — 410 Medical has developed a simple, intuitive solution that allows a single healthcare provider to rapidly deliver fluid to critically ill patients, improving care, and saving lives. Their device allows fast set-up, improves resuscitation speed, minimizes provider fatigue, and frees providers to address other patient care issues simultaneously.This solution is particularly useful in pre-hospital settings and the emergency department and where speed is critical and resources may be limited.It was founded in 2013 and headquartered in Durham, North Carolina.
Atsena Therapeutics — Atsena is a clinical-stage gene therapy company, focused on bringing the life-changing power of genetic medicine to reverse or prevent blindness.
GeneCentric Therapeutics — GeneCentric Therapeutics engages in developing and commercializing molecular diagnostic tests for oncologists and patients. The company currently has two unique platform technologies including The Lung Subtype Platform (LSP) stratifies lung cancer patients into subtypes, which are important for appropriate therapeutic selection. The firstapplication of LSP was licensed to and independently developed by Laboratory Corporation of America Holdings (“LabCorp”) and is now available through its specialty testing business, Integrated Oncology, as HistoPlusSM: Lung Cancer. Its second platform technology is the Hypoxia Signature which has the potential to identify patients that respond to anti-angiogenesis therapies.GeneCentric utilizes a unique partnership model to translate important cancer discoveries into clinically adopted diagnostics for pathologists, clinicians, and, most importantly, patients. The company was incorporated in 2011 and is based in Durham, North Carolina.

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

Investment focus

Biotechnology, Health Care, Therapeutics
Series B, Series C, Post-IPO Equity
United States, United Kingdom, Canada

Portfolio highlights

Vor Biopharma — Shield the healthy cells, expose the cancer - Vor Bio (also known as Vor Biopharma) aims to cure blood cancers through cell and genome engineering.
Commons Clinic — Commons Clinic is a group of world class orthopedic surgeons in Los Angeles, CA. Our orthopedic specialists provide expert care from start to finish.
Spyglass Pharma — Spyglass Pharma focuses on the development of novel treatments for chronic ophthalmic diseases based on technology. The company designs to deliver multiple drugs to address additional ophthalmic indications.

We are the premier, relationship-focused, full-service business bank that offers financial solutions to maximize your operational efficiency.

Investment focus

Health Care, Software, Biotechnology
Debt Financing, Post-IPO Debt, Funding Round
United States, Israel

Portfolio highlights

CallRail — CallRail is a phone call tracking and analytics platform businesses use to understand which marketing campaigns drive leads and conversions. Its intuitive software helps data-driven marketers optimize the performance of their online and offline advertising campaigns, increase sales effectiveness, and improve customer retention.
ScienceLogic — Empower your IT staff & propel your digital transformation with ScienceLogic's AIOps and IT infrastructure monitoring platform.
ShopKeep — Everything ShopKeep does supports growing and independent businesses. Built by and for small business owners, ShopKeep provides an intuitive, secure, iPad point-of-sale system with POS software that empowers merchants to run smarter businesses by optimizing staffing, managing inventory and accessing real time sales reports and customer informationon one seamless, cloud-based platform. With more than 25,000 customers, ShopKeep’s award-winning customer care team is available to help 24/7 and provides a robust support network for growing business owners. ShopKeep is headquartered in New York City, with offices in Portland (OR), Chicago (IL), and Belfast (NIR).

Maverick Ventures is the venture arm of multi-billion dollar investment firm Maverick Capital. Combining the resources of a global firm with the benefits of an agile, focused team, Maverick Ventures supports entrepreneurs from seed through maturity. With over 30 years of early-stage investment experience, the Maverick Ventures team has funded morethan 100 companies in the healthcare, software and deep technology sectors. The highly-experienced team of operating executives and investors at Maverick Ventures generally lead rounds, take board seats and work with management to build successful enterprises.

Investment focus

Health Care, Medical, Biotechnology
Series A, Series C, Seed
United States, Israel, India

Portfolio highlights

Nourish — Achieve your desired health and wellness through personalized nutrition counseling. Nourish is the easiest way to find a registered dietitian and get it covered by your insurance. Find a dietitian today and start your telehealth appointments.
Mandolin — Streamline your infusion center operations with Mandolin. Our AI workers handle back-office tasks within your EHR, leveraging millions of buy-and-bill datapoints to ensure peak efficiency. Focus on delivering life-changing therapies, not paperwork.
Daymark Health — At Daymark, we connect the dots between your primary care physician, your oncologist, and the rest of your care team to create a seamless, supported experience for you 24/7, year-round.

A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.

Investment focus

Software, Information Technology, Internet
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Usul — Rosetta: Query government policy and spending data as it relates to your workflow.
Audos — Where everyday entrepreneurs build small AI companies
The Nuclear Company — The Nuclear Company is a fleet-scale nuclear deployment firm that offers for nuclear sectors.

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