Top 50 Medical Startup Investors in United States in December 2024
A list of 50 angel investors and VC (Venture Capital) funds that invest in Medical startups based in United states. We rank investors based on the number of investments they made in Medical companies from United states. We update this investor list every month.Top 50 Medical Startup Investors in United States in December 2024
Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.
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Investment focus
- Health Care, Medical, Medical Device
- Seed, Pre-Seed, Convertible Note
- United States, Argentina, United Kingdom
Portfolio highlights
- Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
- iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.
- Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.
Foundational partners to ambitious founders at every stage of company-building.
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Investment focus
- Software, Health Care, Biotechnology
- Series B, Series A, Series C
- United States, India, China
Portfolio highlights
- Sana — Sana is an AI company building the next generation of knowledge tools. Designed and engineered in Stockholm, Sweden.
- Fastino — Fastino provides enterprise AI developers with high-performance, task-optimized language models built to scale.
- Avenzo Therapeutics — Developing the next generation of oncology therapies for patients.
SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates.
HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.
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Investment focus
- Biotechnology, Health Care, Software
- Seed, Convertible Note, Pre-Seed
- United States, India, United Kingdom
Portfolio highlights
- MixRift — MIXRIFT - game developers specialized in Mixed Reality
- unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
- Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States, China, United Kingdom
Portfolio highlights
- Metsera — Metsera operates as a clinical-stage biopharmaceutical company.
- Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
- Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.
Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.
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Investment focus
- Health Care, Biotechnology, Medical
- Series B, Series A, Series C
- United States, Singapore, Ireland
Portfolio highlights
- TRex Bio — TRexBio is a discovery stage biotechnology company leveraging cutting-edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for cancer and inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us toidentify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.
- Sunbird Bio — Sunbird Bio, a biotech company, is developing protein-based diagnostic tests that empower diagnosis and treatment of Alzheimer's disease, neurological disorders, and early-stage cancer.
- Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.
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Investment focus
- Health Care, Biotechnology, Software
- Seed, Series A, Funding Round
- United States, Israel, Canada
Portfolio highlights
- AmpUp — Commercial electric vehicle (EV) charging network solutions made simple for everyone. Easily manage and analyze EV charging data from a single dashboard.
- Air Company — We are a carbon utilization company working with industries to create planetary change, taking Earth's excess CO2 and converting it into carbon-negative alcohols and fuels.
- Nimbus Power Systems — Nimbus builds a cleaner world through design and integration of zero-emission fuel cell systems for heavy-duty markets.
Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States
Portfolio highlights
- Marea Therapeutics — Marea Therapeutics is a clinical-stage biotechnology firm that uses the most recent advancements in human genetics to create first-in-class, next-generation medications for cardiometabolic illnesses.
- Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
- Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.
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Investment focus
- Health Care, Biotechnology, Medical
- Series A, Series B, Series C
- United States, United Kingdom, China
Portfolio highlights
- Teleo — Teleo is revolutionizing material moving industries by turning heavy equipment into supervised autonomous machines.
- Zenflow — Zenflow was founded in 2014 by a team of Stanford University Biodesign Fellows working in collaboration with top global urologists. After witnessing patients' frustration with existing treatment options, the founders made it their mission to find a better solution to this large unmet clinical need.
- Lighthouse — Lighthouse is a commercial platform for the travel & hospitality industry. The company transforms complexity into confidence by providing actionable market insights, business intelligence, and pricing tools that maximize revenue growth. Lighthouse was previously known as OTA Insight.
Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.
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Investment focus
- Software, Biotechnology, Health Care
- Series A, Series B, Series C
- United States, United Kingdom, Israel
Portfolio highlights
- Glooko — Glooko's digital health and connected care solutions improve health outcomes for people with diabetes and related chronic conditions.
- Nivoda — Nivoda provides jewellery businesses with a simple solution to strengthen profits, increase efficiency and accelerate growth with its B2B diamond marketplace. Designed to save you time and money whilst giving you access to the world’s diamond supply at the best prices with zero inventory risk, Nivoda is trusted by thousands of retailers all overthe globe.
- Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.
Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.
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Investment focus
- Software, Information Technology, Artificial Intelligence
- Seed, Series A, Series B
- United States, United Kingdom, Canada
Portfolio highlights
- Cake AI — Cake is the fastest way to drive AI initiatives to success. Cake manages the entire stack - compute infrastructure, open source platform elements, common integrations, and pre-built project components.
- Rosie AI — Rosie is ChatGPT for Excel—your on-call expert business analyst. She integrates seamlessly with your spreadsheets to build, update, and explain complex Excel models. Whether you're aiming to streamline data analysis or automate repetitive tasks, Rosie is designed to boost productivity and sharpen decision-making. With Rosie, Excel becomes lessabout wrestling with formulas and more about driving strategic insights.
- StoreCash — StoreCash is a digital bank built for teens and young adults. Unlock massive cashback rewards & learn financial literacy by signing up.
Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States, United Kingdom, Canada
Portfolio highlights
- Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
- Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
- Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.
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Investment focus
- Biotechnology, Health Care, Medical
- Series B, Series A, Series C
- United States, China, Israel
Portfolio highlights
- ADCendo — ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment.
- Avenzo Therapeutics — Developing the next generation of oncology therapies for patients.
- Lomond Therapeutics — Targeting escape mutations in hematological cancers with first and best in class medicines.
Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.
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Investment focus
- Health Care, Medical, Medical Device
- Seed, Series A, Funding Round
- United States, United Kingdom, Canada
Portfolio highlights
- Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
- Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
- Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.
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Investment focus
- Health Care, Biotechnology, Medical
- Funding Round, Seed, Series A
- United States, Canada, United Kingdom
Portfolio highlights
- Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
- BeeReaders — ## Build Setup
- Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.
Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States, Canada, France
Portfolio highlights
- Jupiter BioVentures — Jupiter BioVentures is a creation engine company that focuses on de-risking early-stage projects.
- Valora Therapeutics — Valora Therapeutics is a biotechnology company that provides engineering of chimeric antibodies .
- Autoimmunity BioSolutions — ABS is developing a next-generation, immuno-corrective therapy to restore normal immune function in a genetically-defined subpopulation of autoimmune disease patients.
Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.
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Investment focus
- Biotechnology, Health Care, Medical
- Series A, Series B, Series C
- United States, Switzerland, Canada
Portfolio highlights
- 858 Therapeutics — 858 Therapeutics is a stealth company specializing in the area of healthcare services, pharmaceutical, and biotechnology. The company was founded in 2019 and is headquartered in San Diego, California, USA.
- Antag Therapeutics — Antag Therapeutics operator of a biotechnology company intended to develop metabolic and anti-obesity therapeutic drugs.The company specializes in the development of peptide-based GIP receptor antagonist in order to monitor dietary-related metabolic diseases through the infusion, enabling the healthcare industry to decrease blood flow and lipiduptake in adipose tissue in an efficient manner.
- Pep2Tango Therapeutics — Pep2Tango Therapeutics is a biotechnology company that offers superior unimolecular multi-receptor drugs for obesity and related disorders.
We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.
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Investment focus
- Health Care, Software, Medical
- Seed, Series A, Series B
- United States, Denmark
Portfolio highlights
- Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
- Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
- Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.
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Investment focus
- Biotechnology, Health Care, Medical
- Seed, Funding Round, Series A
- United States, Canada
Portfolio highlights
- KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
- Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
- Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies. they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.
Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.
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Investment focus
- Software, Health Care, Biotechnology
- Series A, Seed, Series B
- United States, United Kingdom, Canada
Portfolio highlights
- Shiru — Discover Shiru. We are an Ingredient Company that Identifies and Creates Functional Ingredients for the Plant-Based Industry.
- Enveda Biosciences — Enveda Biosciences is a biotechnology company building new medicines from plants. It harnesses the complexity of the natural world to tackle today’s biggest healthcare challenges. With the help of the advancements in knowledge graphs, machine learning, and metabolomics, they discover the next generation of small molecules. Its technologiessystematize the discovery of small molecules and novel targets for complex diseases. By probing novel chemical space and mechanisms of action, they are breaking the status quo for challenging diseases with a need for effective treatments, such as fibrosis or neurodegeneration.Enveda, launched in 2019, is based in San Francisco, California.
- Physical Intelligence — Physical Intelligence is bringing general-purpose AI into the physical world.
Investing in powerful, positive change that endures
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Investment focus
- Software, Health Care, Artificial Intelligence
- Series A, Seed, Series B
- United States, India, United Kingdom
Portfolio highlights
- TRACTIAN — TRACTIAN makes it easy for maintenance teams to detect issues in their machines early on. Just like Shazam, it quickly identify the "song" the machine is producing and warn about mechanical failures right when their first signs appear.
- Soda Health — We are a healthcare technology company dedicated to eliminating health inequities through social determinants of health. Our services include supplemental benefit administration, highly customizable member benefit programs with restricted spending and multi-balance capabilities, and robust member data analytics with benefit design recommendations.
- Endo Health — Reverse Your Diabetes With a Game
Green Park & Golf, built on over 50 years of operational and financial experience, seeks investment opportunities that offer above-market returns for its investors. Led by Clay Heighten, M.D., and Carl Soderstrom, the Firm delivers strategic solutions, financial backing and a reliable network to its portfolio companies. The Dallas-based Firm iscurrently looking for investment opportunities in medical-related start-ups.Dr. Heighten founded MedicalEdge Healthcare Group in 1993, and Mr. Soderstrom started PhyServe Physician Services in 1998 to administer the financial and operational needs of MedicalEdge. Together, the companies managed over 550 providers in five major markets. In 2011, the companies were sold to Texas Health Resources, a $3.8 billion health care system. That’s when Green Park & Golf was born.After earning his MBA at Southern Methodist University, Mr. Garcia joined them full-time in May 2011 to actively pursue new investment opportunities and monitor other investments in their portfolio. He has prior professional experience at FedEx, Bold Ventures, and Lone Star Investment Advisors.
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Investment focus
- Health Care, Medical, Biotechnology
- Series A, Seed, Series B
- United States, Israel, Sweden
Portfolio highlights
- Validic — Uncover healthcare trends and personalized care advancements. Learn how technology transforms patient outcomes and manages chronic conditions effectively.
- Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
- Worlds — Worlds is completely re-inventing how organizations see and understand their worlds. Through live, AI-powered models, the company’s clients can remotely see, learn and analyze their worlds in ways that were never possible before.
The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.
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Investment focus
- Health Care, Software, Information Technology
- Seed, Funding Round, Series A
- United States, Canada, United Kingdom
Portfolio highlights
- Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
- Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
- Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.
KdT Ventures is the standard for early-stage frontier science investing.
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Investment focus
- Biotechnology, Health Care, Medical
- Seed, Series A, Series B
- United States, Israel, Germany
Portfolio highlights
- Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
- March Biosciences — Transforming Patient Care by Unlocking New Target Spaces March Biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity
- Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases
MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases
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Investment focus
- Health Care, Medical, Medical Device
- Seed, Series B, Series C
- United States, Israel
Portfolio highlights
- Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
- SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
- Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.
Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.
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Investment focus
- Software, Health Care, Artificial Intelligence
- Seed, Series A, Series B
- United States, Canada, Mexico
Portfolio highlights
- MealMe — MealMe: We compare services for delivery pickup and groceries to ensure that we are the fastest food delivery app, the cheapest food delivery app, and the food delivery app with the largest selection.
- OneRail — OneRail is a final mile delivery orchestration platform providing real-time visibility, actionable data, and data-driven optimization capabilities for its enterprise clients. OneRail’s cloud-based “delivery switch” simplifies same-day and on-demand delivery execution by connecting the demand signal (POS, eCommerce, ERP) with the ecosystem ofdelivery networks and internal fleets in real-time. The result of OneRail’s centralized view of disparate final mile data enables data-driven optimization, positively impacting the dependability, speed, and cost of final mile fulfillment.
- Further — Further is on a mission to empower first-time home buyers to achieve their dream of homeownership with confidence and ease. We simplify the complex home buying process through innovative tools and personalized guidance, ensuring that buyers are well-prepared every step of the way. Our platform offers financial planning, tailored insights, andresources designed to make homeownership more accessible. At Further, we believe that with the right support, anyone can realize their goal of owning a home. Join us as we help make the path to homeownership clear and attainable for all.
Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.
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Investment focus
- Software, Health Care, Artificial Intelligence
- Series A, Series B, Seed
- United States, India, United Kingdom
Portfolio highlights
- Moonvalley — The imagination research company building ML video and image models that captivate.
- Vitara Biomedical — Vitara Biomedical has developed a therapeutic platform to support premature infants. Vitara Biomedical's platform was inspired by natural physiological processes to transform neonatal care.
- Outsmart Education — Join the waitlist and see why higher education will never again be the same.
GV supports innovative founders moving the world forward.
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Investment focus
- Software, Health Care, Biotechnology
- Series A, Series B, Seed
- United States, United Kingdom, Switzerland
Portfolio highlights
- Roboflow — With just a few dozen example images, you can train a working, state-of-the-art computer vision model in less than 24 hours
- Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
- Rox — Transform your sales process with Rox. Leverage AI agents to boost productivity, gain actionable insights, and close deals faster.
The Column Group is a venture capital firm dedicated to creating the next generation of biotechnology companies. They manage over $4 billion in assets and focus on building companies with groundbreaking scientific platforms that have the potential to deliver significant new therapies for unmet medical needs. TCG takes a long-term approach, aimingto develop companies capable of generating multiple product opportunities rather than focusing on quick exits.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States
Portfolio highlights
- Nura Bio — Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders.
- Circle Pharma — Circle Pharma is an early-stage biotechnology company applying proprietary computational design algorithms and innovative chemistry to develop cell-permeable macrocycle peptide therapeutics against important clinical targets. It does this through an iterative, rational design process that deploys large virtual libraries of conformationally diversemacrocycle scaffolds selected for inherent permeability. The company was founded by Matt Jacobson and Scott Lokey in 2012 and is headed by David J. Earp.
- NGM Biopharmaceuticals — Our broad, diverse pipeline of novel, first-in-class medicines spans multiple therapeutic areas and diseases. Every program focuses on a large market indication with high unmet needs and a common goal: delivering outsized impact for patients.
8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.
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Investment focus
- Software, Health Care, Artificial Intelligence
- Seed, Series A, Series B
- United States, Canada, United Kingdom
Portfolio highlights
- Surglogs — Surglogs streamlines and automates the administration of logbooks, medications, supplies, in-services, and drills in healthcare facilities. The outdated pen-and-paper method is replaced with a HIPAA compliant state of the art digital application, complemented with a desktop portal that serves as an administrative dashboard.Surglogs was founded in2015 and headquartered in California, United States.
- Seen Health — We are building a culturally-focused, technology-enabled healthcare organization that integrates comprehensive medical care and social support with a high-touch, interdisciplinary approach. We plan to augment a proven home and community based services model by embracing the unique cultural and healthcare needs of the communities we serve, and empowering our staff with thoughtfully designed technology to scale the highest quality care to many more older adults.
- Workflow — A minimalist collaboration platform for creative teams. Manage tasks, get AI reviews, and share work, all in one place.
TEDCO was created by the Maryland State Legislature in 1998 to facilitate the transfer and commercialization of technology from Maryland’s research universities and federal labs into the marketplace and to assist in the creation and growth of technology-based businesses in all regions of the State. TEDCO is an independent organization thatstrives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy. In Maryland and beyond, TEDCO is a resource of mentoring, funding and networking for entrepreneurs and start-ups that need guidance as they bring innovative concepts to market. TEDCO is more than an early stage funding resource. It is the hub of Maryland’s entrepreneurial network where startups find mentors, organizational assistance, facilities for daily operations, and a roadmap for success.
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Investment focus
- Health Care, Software, Biotechnology
- Seed, Grant, Pre-Seed
- United States, Canada
Portfolio highlights
- Relai.ai — Rely on RELAI agents for your AI reliability needs, from model evaluation and debugging to leveraging state-of-the-art system-level and user-facing safeguards.
- JuneBrain — JuneBrain's network of tele-health device and AI software products are intentionally designed to work together and optimize remote assessment and monitoring of neurological diseases.
- Sybal Corp — Proof of Governance, Patented Enterprise solution designed to measure Policy Effectiveness in real-time and establish immutable record of governance wellness. Governance, Digital Governance, Corporate Governance, Policy, Operational Excellence, GRC
INVESTMENT ADVISORS TO THE FIRST VC FUND DEDICATED TO BIOTECH
INVESTMENT MANAGER OF 9 SUBSEQUENT BIOTECH VC FUNDS
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Investment focus
- Biotechnology, Health Care, Medical
- Series B, Series C, Series A
- United States, Canada, Estonia
Portfolio highlights
- Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
- Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
- Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.
Systematic Pre-Seed Startup Capital
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Investment focus
- Software, SaaS, Health Care
- Seed, Pre-Seed, Convertible Note
- United States, Canada, United Kingdom
Portfolio highlights
- Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
- UBILD — A.I powered construction workforce and vendor procurement platform
- Hutsy — Hutsy is your go-to financial app, offering personalized financial guidance based on your unique situation. Our mission is to help you improve your financial health through tailored advice on spending, savings, credit building, investing, debt management, and more.
AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage
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Investment focus
- Health Care, Biotechnology, Software
- Series A, Seed, Series B
- United States, Cyprus, Ireland
Portfolio highlights
- basys.ai — Basys.ai automates the process of prior authorization and utilization management to improve costs and timeliness for health plans/payers using an AI-based platform. The proprietary platform automates the process of encoding/digitizing the payer policies using machine learning, thus reducing the piloting timeline by up to 9 months.
- Autonomize AI — Autonomize AI is a human-centric AI platform that learns from multi-structured clinical and biomedical data and pairs it with human context to aid decision-making and data discovery. They extract contextual information from multi-structured healthcare data, enrich with human know-how, and aid decision-making and data discovery.
- Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.
Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.
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Investment focus
- Software, Information Technology, Internet
- Series A, Seed, Series B
- United States, United Kingdom, Brazil
Portfolio highlights
- xAI — XAI is an AI company that develops a platform to accelerate human scientific discovery. The company primarily focuses on developing advanced AI systems that are truthful, competent, and maximally beneficial for all of humanity. Its mission is to understand the true nature of the universe.
- HappyRobot — Happyrobot is the AI that extracts quantitative data from geospatial imagery with English queries
- Sinatra — Sinatra's AI copilot for e-commerce assists medium and big firms in streamlining operations. through process automation, real-time anomaly detection and analysis, auditing of sales pipelines to increase profitability and cut expenses, and platform integration.
Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact
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Investment focus
- Health Care, Software, Biotechnology
- Seed, Series A, Series B
- United States, Canada, Argentina
Portfolio highlights
- Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
- Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and
- Zero Point Five Therapeutics — A drug development company treating soil transmitted helminthiasis (STH) through the FDA as a single dose formulation. STH is a disease impacting poor rural communities of color with poor sewage systems.
SpringTide is an investment firm supporting the world's best healthcare innovators. Learn more and let's get in touch!
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Investment focus
- Health Care, Medical, Software
- Seed, Series A, Funding Round
- United States, Israel
Portfolio highlights
- Nest Health — Nest Health is a primary care company that offers whole person, whole family care for families from birth through age five in urban areas. Nest offers primary and pediatric care for families, made affordable and convenient.
- Tava Health — Tava Health is a comprehensive mental health service that partners with employers to provide convenient, high-quality, accessible mental health resources to employees and their families. Our technology-enabled platform empowers our clients to match with world-class therapists and psychologists without needing to navigate the complexities of the health insurance system.
- Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.
Powering Breakthroughs in Life Sciences
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Investment focus
- Biotechnology, Health Care, Pharmaceutical
- Series B, Series A, Series C
- United States, United Kingdom, Canada
Portfolio highlights
- AstronauTx — AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.
- Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
- Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies
RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series B, Series C, Series A
- United States, United Kingdom, Canada
Portfolio highlights
- ADCendo — ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment.
- Metsera — Metsera operates as a clinical-stage biopharmaceutical company.
- Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.
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Investment focus
- Software, Health Care, Information Technology
- Series A, Seed, Series B
- United States, United Kingdom, Germany
Portfolio highlights
- Radiant — Clean. Portable. Safe. Energy
- Even — Even is a health tech company and healthcare provider that partners directly with the top hospitals in the country to offer you unlimited diagnostics, consultations, and 50 lakh worth of hospitalisations all with one monthly subscription cost.
- Impulse Space — Economical and nimble last-mile space payload delivery
Building Companies that Shape the Future
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Investment focus
- Health Care, Biotechnology, Software
- Series B, Series A, Series C
- United States, Canada, Switzerland
Portfolio highlights
- Scope3 — Scope3 is on a mission to decarbonize media and advertising.
- Suki — Suki is an AI-powered voice assistant that lifts the administrative burden from clinicians, so they have time to focus on what matters - patient care.
- Vanilla — Vanilla is an estate planning platform that allows advisors to unlock new value for clients and prospects alike, no expertise required.
First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.
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Investment focus
- Software, Information Technology, Health Care
- Seed, Series A, Series B
- United States, Canada, India
Portfolio highlights
- Reducto — Reducto is an API that provides high quality data ingestion for large language models (LLMs). It works with any vector database or embedding system. It can parse PDFs, Excel, PowerPoint, and more.
- Omnea — The all-in-one procurement platform. Request purchases, automate approvals, and streamline your procurement process in one centralised solution.
- Prepared — We are harnessing the power of everyday technology to enhance the way that people communicate during emergencies.
Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots
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Investment focus
- Health Care, Wellness, Medical
- Seed, Funding Round, Pre-Seed
- United States, Canada, United Kingdom
Portfolio highlights
- AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
- Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
- Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs
Sanofi Ventures invests in top tier biotherapeutic and digital health entrepreneurs who focus on helping patients and transforming the healthcare system.
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Investment focus
- Biotechnology, Health Care, Medical
- Series B, Series A, Series C
- United States, United Kingdom, Israel
Portfolio highlights
- Q32 Bio — Q32 Bio is developing drugs targeting powerful regulators of both the innate and adaptive immune systems with the goal of re-balancing the immune system.
- Atropos Health — We create high-quality, personalized, real-world evidence in minutes and at scale, creating the trusted currency of value in healthcare
- Nuvig Therapeutics — Nuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune homeostasis, rebalance immune function following inflammation, and improve the treatment options for patients. Nuvig is building a pipeline of novel immune therapeutics for chronic inflammatory and autoimmunediseases.
Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.
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Investment focus
- Biotechnology, Health Care, Medical
- Series A, Series B, Funding Round
- United States, Canada
Portfolio highlights
- Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
- Synaptrix — Synaptrix is a medical device start-up company dedicated to developing and commercializing drug-free pain management solutions for postoperative joint surgery patients. The proprietary NOVABLOC system is a procedure-based solution that delivers a novel type of electrical stimulation. Human feasibili
- AtaCor Medical — AtaCor Medical - Designing innovative solutions to deliver temporary, interim, and permanent cardiac pacing when, and where it matters most.
Martin Ventures provides capital, operational support and mentoring to assist entrepreneurs who want to be catalysts for change. Focusing primarily on health care and technology initiatives, Martin Ventures’ unique approach allows the leadership of our portfolio companies to more acutely focus on the optimal execution of their vision and strategywhile quickly scaling and growing their businesses into successful, profitable organizations.
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Investment focus
- Health Care, Medical, Hospital
- Series A, Seed, Funding Round
- United States
Portfolio highlights
- OncoLens — OncoLens develops technologies that improve cancer treatment planning, simplify tumor board management, facilitate survivorship care planning, and automate accreditation and quality reporting through an intelligent workflow engine that streamlines business processes and enables more informed clinical decision-making.
- Livara Health — The SpineZone solution works with the body's inherent ability to heal back and joint pain without surgery, injection, or opioids.
- Harbor Health — Harbor Health is a multi-specialty clinic group that provides smarter health care using technology. The company co-creates a health path that is dedicated to knowing individuals' health goals with the guidance of specialists when needed. Harbor Health was founded in 2022 and is based in Austin, Texas.
A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.
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Investment focus
- Software, Information Technology, Internet
- Series A, Seed, Series B
- United States, United Kingdom, Canada
Portfolio highlights
- Team-GPT — Team-GPT helps companies use any AI model, find the right use cases for it, keep data safe, organize workflows, and track results. It speed up work with pre-made prompts, use cases, and editable AI Pages. Team-GPT is built with enterprise security, privacy, and compliance in mind from day one.
- HomeBoost — HomeBoost operates as a home energy platform.
- Enveda Biosciences — Enveda Biosciences is a biotechnology company building new medicines from plants. It harnesses the complexity of the natural world to tackle today’s biggest healthcare challenges. With the help of the advancements in knowledge graphs, machine learning, and metabolomics, they discover the next generation of small molecules. Its technologiessystematize the discovery of small molecules and novel targets for complex diseases. By probing novel chemical space and mechanisms of action, they are breaking the status quo for challenging diseases with a need for effective treatments, such as fibrosis or neurodegeneration.Enveda, launched in 2019, is based in San Francisco, California.
We are the premier, relationship-focused, full-service business bank that offers financial solutions to maximize your operational efficiency.
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Investment focus
- Health Care, Software, Biotechnology
- Debt Financing, Post-IPO Debt, Funding Round
- United States, Israel
Portfolio highlights
- CallRail — CallRail is a phone call tracking and analytics platform businesses use to understand which marketing campaigns drive leads and conversions. Its intuitive software helps data-driven marketers optimize the performance of their online and offline advertising campaigns, increase sales effectiveness, and improve customer retention.
- ScienceLogic — Empower your IT staff & propel your digital transformation with ScienceLogic's AIOps and IT infrastructure monitoring platform.
- ShopKeep — Everything ShopKeep does supports growing and independent businesses. Built by and for small business owners, ShopKeep provides an intuitive, secure, iPad point-of-sale system with POS software that empowers merchants to run smarter businesses by optimizing staffing, managing inventory and accessing real time sales reports and customer informationon one seamless, cloud-based platform. With more than 25,000 customers, ShopKeep’s award-winning customer care team is available to help 24/7 and provides a robust support network for growing business owners. ShopKeep is headquartered in New York City, with offices in Portland (OR), Chicago (IL), and Belfast (NIR).
Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.
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Investment focus
- E-Commerce, Software, Health Care
- Seed, Series A, Series B
- United States, United Kingdom, Spain
Portfolio highlights
- Atllas — Atllas is a tech-based real estate organization that leverages software tools to offer brokerage services.
- Fleet — Fleet is a mobility-as-a-Service software for enterprise transportation needs.
- Amulet — Amulet is shining a light on invisible threats in our food system. Amulet has two core brands: - Allergy Amulet helps consumers determine whether their foods are safe by detecting potentially life-threatening allergenic ingredients. - Amulet Scientific equips businesses and manufacturers with tools to help ensure the safety of their food supplychain. Learn more: www.allergyamulet.com www.amuletscientific.com
DIGITAL HEALTH / AI
DIGITAL HEALTH / AI GENE / CELL THERAPIES
NASDAQ: RCKT GENE / CELL THERAPIES
NASDAQ: RCKT GENOMICS / DIAGNOSTICS GENOMICS / DIAGNOSTICS
SYNTHETIC
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Investment focus
- Biotechnology, Health Care, Medical
- Seed, Series A, Series B
- United States, United Kingdom, Brazil
Portfolio highlights
- SyntaxBio — SyntaxBio develops CRISPR/Cas9-based, genetic programming platform that converts cells into biological computers using DNA-based instructions that read like lines of code. SyntaxBio's platform can program cells without the need for consistent external intervention.
- Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
- Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.
Initialized Capital is an early-stage venture capital firm focused on the seed. Initialized has 6 investing partners and over $3.2B under management over five core funds since its founding in 2012. The firm's startups have created in aggregate over $200B in market value so far.
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Investment focus
- Software, SaaS, Health Care
- Seed, Series A, Series B
- United States, Canada, United Kingdom
Portfolio highlights
- AstroForge — We mine asteroids to extract valuable minerals in space at a lower cost and smaller carbon footprint than the current terrestrial mining methods.
- Beyond Aero — Beyond Aero is a Toulouse-based aerospace company founded in 2020
- Star Catcher — Star Catcher is creating the first energy grid for space. Spacecraft connect to the network and receive energy via existing solar arrays, requiring no retrofit to utilize.
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