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Top 50 Medical Startup Investors in United States in April 2025

Last updated: Apr 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Medical startups based in United states. We rank investors based on the number of investments they made in Medical companies from United states. We update this investor list every month.

Top 50 Medical Startup Investors in United States in April 2025

Investor	Medical United States investments
Innova Memphis	58
New Enterprise Associates	39
SOSV	37
ARCH Venture Partners	37
Polaris Partners	32
Connecticut Innovations	30
Third Rock Ventures	28
F-Prime Capital	28
Alumni Ventures	28
Canaan Partners	27
Wavemaker 360	26
Wisconsin Investment Partners	26
Atlas Venture	26
OrbiMed	26
Alexandria Venture Investments	25
Rock Health Capital	25
BioAdvance	25
Versant Ventures	25
KdT Ventures	23
Lux Capital	22
General Catalyst	22
Green Park & Golf Ventures	22
Houston Angel Network	22
MB Venture Partners	22
Gaingels	21
Google Ventures	20
Khosla Ventures	20
Domain Associates	20
TEDCO	20
The Column Group	20
8VC	19
Asset Management Ventures (AMV)	19
Andreessen Horowitz	19
Portfolia	19
SpringTide Ventures	19
Right Side Capital Management	18
Founders Fund	18
RA Capital Management	18
MPM Capital	17
Sanofi Ventures	17
Venrock	17
StartUp Health	17
First Round Capital	17
True Ventures	16
Hatteras Venture Partners	16
Martin Ventures	16
Square 1 Bank	16
Omega Funds	16
Morgenthaler Ventures	15
Great Oaks Venture Capital	15

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Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, Canada

Portfolio highlights

Ceramic.ai — Ceramic.ai builds enterprise-grade infrastructure to optimize how companies train and deploy their AI models
Vori Health — Meet Vori Health, the new virtual and in-person musculoskeletal healthcare company that will help you get that spring back into your step.
Ceramic — Next generation AI training systems for better models with less compute, less time, and lower costs.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, China, United Kingdom

Portfolio highlights

Rhygaze — RhyGaze is at the forefront of developing a novel first-in-class gene therapy aimed at improving vision in patients suffering from retinal diseases.
Kardigan — Kardigan is building the heart health company of the future focused on developing medicines to make cardiovascular disease curable, preventable, and no longer the leading cause of death.
Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Ireland, Singapore

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
Leyden Labs — Leyden Labs helps people live freely by developing products that protect from known and new respiratory viruses.
Auron Therapeutics — A differentiated approach to cure cancer.

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
VeraDermics — VeraDermics Inc. is a dermatology pharmaceutical start-up, makers of WartPatch
PHȲND — PHȲND is a subscription-free cloud gaming platform that offers a way to discover, play, and socialize across a wide variety of games.

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.
Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

Ethena — Enabling the Internet Bond
Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.
Bluebird Kids Health — Bluebird Kids Health is launching a proprietary technology platform to proactively manage and coordinate treatment, with AI enhancing and simplifying the experience for its clinical team.

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Patlytics — Patent discovery, analytics, comparison, and workflow. Simplified via Artificial Intelligence.
Ceramic.ai — Ceramic.ai builds enterprise-grade infrastructure to optimize how companies train and deploy their AI models
Prezent AI — Presentation productivity platform for enterprise teams. Add zen to your presentations!

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, United Kingdom, Israel

Portfolio highlights

WiseLayer — WiseLayer's AI empowers finance teams to improve profitability & efficiency in minutes per week
Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.
Wise Layer — WiseLayer makes AI-powered digital workers for finance and accounting teams.It's AI digital workforce includes: - Angela, the AI agent for Accruals & Rev Rec (hire her at www.accruals.ai) - Dennis, the AI agent for Discrepancies & Financial Anomalies (hire him at www.discrepancies.ai) - … with the 4 newest AI agents eachspecializingin the following tasks: (1) bank reconciliations, (2) fixed asset depreciation & amortization, (3) lease accounting, and (4) prepaid expenses.

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

DropCap — We are an innovative foreign rights literary agency that elevates exceptional books to the worldwide stage.
Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

vVardis — vVardis is a personal oral care brand by Dres Abivardi.vVardis is both the professional dental CURODONT™ line and the oral care vVardis products – both with the proprietary CUROLOX® & WX Technology – will form one oral care powerhouse.
Stairway Medical — Stairway Medical is a developer of implantable brain-computer interface technology.
Helicore Biopharma — Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders.

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Seed
United States, Canada, France

Portfolio highlights

Meiogenix — Meiogenix is a biotech company developing breeding technologies to unlock the unexplored genetic diversity of organisms. Meiogenix expands the natural biodiversity and helps developing new products to address global food and industrial challenges.
nChroma Bio — nChroma Bio's integrated product engine allows for safe, accurate, and targeted in vivo administration, addressing major shortcomings of current genetic medicine techniques.
Nuvig Therapeutics — Nuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune homeostasis, rebalance immune function following inﬂammation, and improve the treatment options for patients. Nuvig is building a pipeline of novel immune therapeutics for chronic inflammatory and autoimmunediseases.

We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.

Investment focus

Health Care, Software, Medical
Seed, Series A, Series B
United States, Denmark

Portfolio highlights

Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

Investment focus

Biotechnology, Health Care, Medical
Seed, Funding Round, Series A
United States, Canada

Portfolio highlights

KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies. they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

Antag Therapeutics — Antag Therapeutics operator of a biotechnology company intended to develop metabolic and anti-obesity therapeutic drugs.The company specializes in the development of peptide-based GIP receptor antagonist in order to monitor dietary-related metabolic diseases through the infusion, enabling the healthcare industry to decrease blood flow and lipiduptake in adipose tissue in an efficient manner.
Helicore Biopharma — Helicore Biopharma is at the forefront of developing cutting-edge treatments for obesity and related disorders.
Light Horse Therapeutics — Light Horse Therapeutics is the gene editing applied to small-molecule drug discovery, pioneering approaches to target the root causes of disabling and life-threatening diseases. Its advanced platform identifies cryptic chemically accessible functional domains within targets that are critical in disease biology. Our initial focus addresseshigh-value, historically challenging oncology targets with the opportunity to apply the technology to other therapeutic areas in the future.

KdT Ventures is the standard for early-stage frontier science investing.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Israel, Germany

Portfolio highlights

Shiprocket — Shiprocket is India's most-used eCommerce logistics and shipping software solution for the best courier services. Avail features like COD (Cash on Delivery), prepaid delivery, automated shipping, etc.
March Biosciences — Transforming Patient Care by Unlocking New Target Spaces March Biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity
Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Biotechnology
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Lanai — The AI Empowerment Platform - Help your team achieve the extraordinary in the age of AI.
Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.
Frontera Health — Save 5-6 hours on every ABA diagnosis and assessment report. Frontera ABA clinical report automation software helps you spend more time with patients. Let our BCBA-trained AI do the heavy lifting.

Investing in powerful, positive change that endures

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, India, United Kingdom

Portfolio highlights

Podqi — Podqi is an AI-powered platform specifically designed for entertainment companies to automate monitoring, takedown, and retroactive compensation for infringement on their portfolio of IP.
Anthropic — An AI safety and research company that's working to build reliable, interpretable, and steerable AI systems.
Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.

Green Park & Golf, built on over 50 years of operational and financial experience, seeks investment opportunities that offer above-market returns for its investors. Led by Clay Heighten, M.D., and Carl Soderstrom, the Firm delivers strategic solutions, financial backing and a reliable network to its portfolio companies. The Dallas-based Firm iscurrently looking for investment opportunities in medical-related start-ups.Dr. Heighten founded MedicalEdge Healthcare Group in 1993, and Mr. Soderstrom started PhyServe Physician Services in 1998 to administer the financial and operational needs of MedicalEdge. Together, the companies managed over 550 providers in five major markets. In 2011, the companies were sold to Texas Health Resources, a $3.8 billion health care system. That’s when Green Park & Golf was born.After earning his MBA at Southern Methodist University, Mr. Garcia joined them full-time in May 2011 to actively pursue new investment opportunities and monitor other investments in their portfolio. He has prior professional experience at FedEx, Bold Ventures, and Lone Star Investment Advisors.

Investment focus

Health Care, Medical, Biotechnology
Series A, Seed, Series B
United States, Israel, Sweden

Portfolio highlights

Validic — Uncover healthcare trends and personalized care advancements. Learn how technology transforms patient outcomes and manages chronic conditions effectively.
Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
Worlds — Worlds is completely re-inventing how organizations see and understand their worlds. Through live, AI-powered models, the company’s clients can remotely see, learn and analyze their worlds in ways that were never possible before.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

CO/AI — CO/AI is a community focused on fostering expertise and skills in artificial intelligence (AI) among individuals and businesses. This initiative aims to prepare participants for success in an increasingly AI-driven economy through various educational and collaborative efforts.
1up — 1up is a competitive AI for users to observe and understand everything their competitors are doing. 1up accelerates and automates the competitive experience for teams. 1up enables teams to save hours of manual effort in product, sales, and marketing, understand what their competitors are building and saying, and win competitive deals faster andeasier than ever before.
Utila — Securely manage, build, and scale your institutional digital asset operations with Utila's MPC-powered platform. Leverage unparalleled security, robust governance and countless ecosystem integrations.

GV supports innovative founders moving the world forward.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Seed
United States, United Kingdom, Switzerland

Portfolio highlights

comstruct — comstruct is working on a platform that will allow construction companies to digitize and automate material purchasing. All delivery bills, invoices, and purchase orders, as well as processes such as invoice verification, can be exchanged digitally with suppliers. All data pertaining to the purchasing process is made available for documentation,evaluation, and process optimization.
Mimic Networks — Mimic's new enterprise ransomware defense technology provides a last line of defense against ransomware attacks and protects your critical data against theft and encryption.
Perceive Pharma — Perceive Pharma operates as a pharmaceutical company. Perceive Pharma develops innovative small molecule neuroprotective treatments.

Khosla Ventures invests in companies that are bold, early, and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs.Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech, digital health, medtech anddiagnostics, therapeutics, and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Onyx — The open-source AI enterprise search platform that helps teams find information across all company data.
Tempero Bio — Tempero Bio develops treatments for Substance Use Disorders as a clinical-stage biopharmaceutical company.
Resource Chemical — Resource Chemical develops CO2 into high-performance plastics that do not pollute the environment. The company's headquarters are in Berkeley, California.

INVESTMENT ADVISORS TO THE FIRST VC FUND DEDICATED TO BIOTECH INVESTMENT MANAGER OF 9 SUBSEQUENT BIOTECH VC FUNDS

Investment focus

Biotechnology, Health Care, Medical
Series B, Series C, Series A
United States, Canada, Estonia

Portfolio highlights

Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

Investment focus

Health Care, Software, Biotechnology
Seed, Grant, Pre-Seed
United States, Canada

Portfolio highlights

Pathotrak — We've developed the most cost effective foodborne pathogen dection test. We can provide results up to 6x faster than other tests.
Irazu Oncology — Our mission is to develop a superior vaccine platform to improve clinical outcomes for cancer patients
HeMemics Biotechnologies, Inc. — The company develops a low-cost biosensor platform with graphene-based sensors to detect multiple pathogens in one test within 2 minutes.

The Column Group (TCG) is a venture ecosystem dedicated to fueling scientific innovation in the life sciences industry.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Rapt Therapeutics — RAPT Therapeutics is a clinical stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in oncology and inflammatory diseases. Utilizing its proprietary discovery and development engine, the company is developing highly selectivesmall molecules designed to modulate the critical immune responses underlying these diseases. In its first four years since inception, RAPT has discovered and advanced two unique drug candidates, each targeting C-C motif chemokine receptor 4. The company’s lead oncology drug candidate, FLX475, reached the clinic in just two and a half years with its lead inflammation drug candidate, RPT193, also in the clinic. The company is also pursuing a range of targets, including general control nonderepressible 2 and hematopoietic progenitor kinase 1, that are in the discovery stage of development.
Nura Bio — Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders.
Circle Pharma — Circle Pharma is an early-stage biotechnology company applying proprietary computational design algorithms and innovative chemistry to develop cell-permeable macrocycle peptide therapeutics against important clinical targets. It does this through an iterative, rational design process that deploys large virtual libraries of conformationally diversemacrocycle scaffolds selected for inherent permeability. The company was founded by Matt Jacobson and Scott Lokey in 2012 and is headed by David J. Earp.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Saronic — Providing naval and maritime forces with the most intelligent Autonomous Surface Vessels available.
Patlytics — Patent discovery, analytics, comparison, and workflow. Simplified via Artificial Intelligence.
Tempero Bio — Tempero Bio develops treatments for Substance Use Disorders as a clinical-stage biopharmaceutical company.

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

Investment focus

Health Care, Biotechnology, Software
Series A, Seed, Series B
United States, Cyprus, Ireland

Portfolio highlights

basys.ai — Basys.ai automates the process of prior authorization and utilization management to improve costs and timeliness for health plans/payers using an AI-based platform. The proprietary platform automates the process of encoding/digitizing the payer policies using machine learning, thus reducing the piloting timeline by up to 9 months.
Autonomize AI — AI Copilots for Healthcare & Life Sciences. Empower knowledge workers, reduce administrative burden and improve health outcomes.
Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

Flock Safety — From creating safer neighborhoods to protecting employees and property, we help you deter and solve crime with tools customized and scaled to your needs.
Rune Technologies — Rune Technologies' objective is to consistently deliver innovative logistics technology to support the free world's enduring values, enable quick triumphs, and maintain peace through strength.
Mercury — Powerful banking. Simplified finances. Apply in 10 minutes for business banking that transforms how you operate.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Software, Biotechnology
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and
Zero Point Five Therapeutics — A drug development company treating soil transmitted helminthiasis (STH) through the FDA as a single dose formulation. STH is a disease impacting poor rural communities of color with poor sewage systems.

SpringTide is a venture capital that provides investment in the health tech industry. The firm was founded in 2018 and is headquartered in Cambridge, Massachusetts, United States.

Investment focus

Health Care, Medical, Software
Seed, Series A, Funding Round
United States, Israel

Portfolio highlights

Nest Health — Nest Health is a primary care company that offers whole person, whole family care for families from birth through age five in urban areas. Nest offers primary and pediatric care for families, made affordable and convenient.
Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.
Paterna Biosciences — Male infertility care is lagging. Paterna is changing that with in vitro spermatogenesis. Explore our science and meet the team.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
UBILD — A.I powered construction workforce and vendor procurement platform
Hutsy — Hutsy Financial is a financial services company that provides mobile banking, early payroll access and credit building products. In partnership with Peoples Trust we provide a prepaid debit card that our users can spend with. We also offer cash back on all purchases, spending insights, and categorizations to provide valuable insight on where yourmoney is going. Hutsy was recently on CBC’s Dragons Den where we raised our pre-seed funding round of $500,000 to bring our product to life.

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

ThreatMate — ThreatMate revolutionizes cybersecurity by offering a single platform with inquisitive security capabilities for the middle market. The company was founded by a team of serial entrepreneurs and cybersecurity experts that aims to protect mid-sized companies from cyber threats.
Biosphere — Biosphere engages in manufacturing commercial-scale fermentation products and robotic greenhouses.
Cognition — Cognition is an applied artificial intelligence lab that focuses on reasoning and code.

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

Investment focus

Biotechnology, Health Care, Therapeutics
Series B, Series C, Post-IPO Equity
United States, United Kingdom, Canada

Portfolio highlights

Curevo — focused on a new generation of adjuvanted subunit vaccines Learn More Our Focus We're dedicated to developing non-mRNA vaccines for unmet medical needs Curevo Vaccine is a clinical-stage biotech company dedicated to developing next-generation non-mRNA vaccines. We focus on one need at a time, allowing us to bring effective and better-tolerated vaccines to market quickly
Surrozen — Surrozen is a biotechnology company discovering and developing drug candidates to selectively modulate the Wnt pathway. Surrozen is developing tissue-specific antibodies designed to engage the body’s existing biological repair mechanisms with potential application across multiple disease areas, including diseases of the intestine, liver, retina,cornea, lung, kidney, cochlea, skin, pancreas and central nervous system.
Vivace Therapeutics — Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway. At Vivace Therapeutics, they pursue their work with passion, driven by a conviction to help people fight cancer and live life to the fullest. Based in the San Francisco Bay Area, Vivace Therapeutics is anoncology-focused portfolio-based drug discovery and development company adopting a capital-efficient and modality-indifferent approach to bring novel therapies to patients in need. Their experienced management team and world-class scientists work to advance promising drugs and therapeutic technologies that they believe can help conquer cancer.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series B, Series A, Series C
United States, United Kingdom, Canada

Portfolio highlights

Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Umoja Biopharma — Pioneering immunotherapy by reprogramming T cells in vivo to target cancer cells.
Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies

Sanofi Ventures invests in top tier biotherapeutic and digital health entrepreneurs who focus on helping patients and transforming the healthcare system.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, United Kingdom, France

Portfolio highlights

AdvanCell — AdvanCell is an Australian radiopharmaceutical firm in the clinical stages that has developed the Targeted Alpha Therapy platform technology, a cutting-edge cancer treatment.
Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
Atalanta Therapeutics — Atalanta was created to address the urgent global need for interventions to treat neurodegenerative diseases.

Building Companies that Shape the Future

Investment focus

Health Care, Biotechnology, Software
Series B, Series A, Series C
United States, Canada, Switzerland

Portfolio highlights

Oumi — Building truly open, reliable frontier AI.
Suki — Suki is an AI-powered voice assistant that lifts the administrative burden from clinicians, so they have time to focus on what matters - patient care.
GenLogs — Get ready to have your operations supercharged! Our real-time data on all trucks in America helps you find the right capacity at the right time.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

Investment focus

Software, Information Technology, Internet
Seed, Series A, Series B
United States, Canada, India

Portfolio highlights

Crossmint — Crossmint is the leading enterprise-grade developer platform to build onchain. Crossmint's suite of products includes wallets, tokenization, payments, and more; and powers 40,000+ companies and developers, including Fortune 500 companies and major brands like Mastercard, Adidas, Red Bull, Coinbase, Phantom, and more.
Town — The complete tax solution for small businesses like yours
Dyna Robotics — We're making Al-powered robotic automation accessible for businesses of all sizes by building affordable, easy-to-deploy Autonomous Al Robots.

A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Riley — Riley learns and grows with your family, offering personalized, data-backed guidance so you're ready for anything that life - or your kids - throws your way.
Bible Chat — Chat with the AI-powered Bible assistant to get answers to your faith-related questions and any life challenges you face. Explore now the Word of God!
Moderne — Manage dependencies, update frameworks, and improve code quality in minutes, not months. Request a demo or join Beta.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
United States, Canada

Portfolio highlights

Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
Synaptrix — Synaptrix is a medical device start-up company dedicated to developing and commercializing drug-free pain management solutions for postoperative joint surgery patients. The proprietary NOVABLOC system is a procedure-based solution that delivers a novel type of electrical stimulation. Human feasibili
AtaCor Medical — AtaCor Medical Inc., is a San Clemente-based medical device maker. It designs innovative solutions to deliver temporary, interim, and permanent cardiac pacing when, and where it matters most.

Martin Ventures provides capital, operational support and mentoring to assist entrepreneurs who want to be catalysts for change. Focusing primarily on health care and technology initiatives, Martin Ventures’ unique approach allows the leadership of our portfolio companies to more acutely focus on the optimal execution of their vision and strategywhile quickly scaling and growing their businesses into successful, profitable organizations.

Investment focus

Health Care, Medical, Hospital
Series A, Seed, Funding Round
United States

Portfolio highlights

OncoLens — OncoLens develops technologies that improve cancer treatment planning, simplify tumor board management, facilitate survivorship care planning, and automate accreditation and quality reporting through an intelligent workflow engine that streamlines business processes and enables more informed clinical decision-making.
Livara Health — The SpineZone solution works with the body's inherent ability to heal back and joint pain without surgery, injection, or opioids.
Harbor Health — Harbor Health is a multi-specialty clinic group that provides smarter health care using technology. The company co-creates a health path that is dedicated to knowing individuals' health goals with the guidance of specialists when needed. Harbor Health was founded in 2022 and is based in Austin, Texas.

We are the premier, relationship-focused, full-service business bank that offers financial solutions to maximize your operational efficiency.

Investment focus

Health Care, Software, Biotechnology
Debt Financing, Post-IPO Debt, Funding Round
United States, Israel

Portfolio highlights

CallRail — CallRail is a phone call tracking and analytics platform businesses use to understand which marketing campaigns drive leads and conversions. Its intuitive software helps data-driven marketers optimize the performance of their online and offline advertising campaigns, increase sales effectiveness, and improve customer retention.
ScienceLogic — Empower your IT staff & propel your digital transformation with ScienceLogic's AIOps and IT infrastructure monitoring platform.
ShopKeep — Everything ShopKeep does supports growing and independent businesses. Built by and for small business owners, ShopKeep provides an intuitive, secure, iPad point-of-sale system with POS software that empowers merchants to run smarter businesses by optimizing staffing, managing inventory and accessing real time sales reports and customer informationon one seamless, cloud-based platform. With more than 25,000 customers, ShopKeep’s award-winning customer care team is available to help 24/7 and provides a robust support network for growing business owners. ShopKeep is headquartered in New York City, with offices in Portland (OR), Chicago (IL), and Belfast (NIR).

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Switzerland, United Kingdom

Portfolio highlights

Windward Bio — Windward Bio is a clinical-stage drug development company focused on improving outcomes for individuals with advanced immunological diseases, particularly severe respiratory conditions. The company is advancing a monoclonal antibody targeting thymic stromal lymphopoietin (TSLP) into phase 2 development while creating innovative bispecific programsfor various immunological disorders. Led by a team of biopharmaceutical executives, Windward Bio aims to address significant unmet medical needs in this field.
Alleviant Medical — Interventional therapy for congestive heart failure
Callio Therapeutics — Callio Therapeutics focuses on developing next-generation, multi-payload antibody-drug conjugates to maximize therapeutic benefits.

Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Canada, France

Portfolio highlights

Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.

Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.

Investment focus

E-Commerce, Software, Health Care
Seed, Series A, Series B
United States, United Kingdom, Spain

Portfolio highlights

Fleet — Fleet is a mobility-as-a-Service software for enterprise transportation needs.
Amulet — Amulet is shining a light on invisible threats in our food system. Amulet has two core brands: - Allergy Amulet helps consumers determine whether their foods are safe by detecting potentially life-threatening allergenic ingredients. - Amulet Scientific equips businesses and manufacturers with tools to help ensure the safety of their food supplychain. Learn more: www.allergyamulet.com www.amuletscientific.com
Tracer Biotechnologies — Tracer Biotechnologies is a biotechnology company that offers monitoring services for oncology patients.

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