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Top 50 Medical Startup Investors in United States in January 2026

Last updated: Jan 2026 A list of 50 angel investors and VC (Venture Capital) funds that invest in Medical startups based in United states. We rank investors based on the number of investments they made in Medical companies from United states. We update this investor list every month.

Top 50 Medical Startup Investors in United States in January 2026

Investor	Medical United States investments
Innova Memphis	58
ARCH Venture Partners	40
SOSV	37
New Enterprise Associates	37
Polaris Partners	34
Alumni Ventures	33
Connecticut Innovations	32
OrbiMed	28
Atlas Venture	28
F-Prime	28
Third Rock Ventures	28
Canaan Partners	27
Wavemaker 360	27
Alexandria Venture Investments	25
Wisconsin Investment Partners	25
BioAdvance	25
Rock Health Capital	25
KdT Ventures	24
Lux Capital	23
Versant Ventures	23
General Catalyst	23
8VC	22
MB Venture Partners	22
Green Park & Golf Ventures	22
Khosla Ventures	22
TEDCO	21
Gaingels	21
Domain Associates	20
Asset Management Ventures (AMV)	20
The Column Group	20
Google Ventures	20
Houston Angel Network	20
Sanofi Ventures	20
Martin Ventures	19
Andreessen Horowitz	19
SpringTide Ventures	19
Right Side Capital Management	19
Sante Ventures	19
Founders Fund	18
Portfolia	18
Hatteras Venture Partners	17
RA Capital Management	17
Omega Funds	17
MPM Capital	17
First Round Capital	17
Maverick Ventures	17
StartUp Health	17
Venrock	17
SV Angel	16
True Ventures	16

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Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Funding Round
United States, Argentina, United Kingdom

Portfolio highlights

HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.
Soiltech Wireless — Soiltech Wireless is a developer of ag-tech solutions to design electronic devices for agricultural professionals. Its product provides real-time data to drive efficiency and optimize quality. It also provides actionable data without installation hassles and creates scalable monitoring solutions for farmers.The company was founded in 2019 and isheadquartered in Rupert, Idaho.

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, China, United Kingdom

Portfolio highlights

Paradigm — Paradigm is building a platform that enables equitable access to clinical trials while enhancing efficiency and improving ease of use for providers.
Basking Biosciences — Basking Biosciences is a startup that’s developing a therapy to restore blood flow to the brain during ischemic stroke, preventing hemorrhage and long-term damage.
Soufflé Therapeutics — Soufflé Therapeutics is a biotechnology company specializing in the development of nucleic acid medicines designed for precise delivery and targeting of disease-causing cells. The company's mission is to create potent, precise, and safe medicines that can be tailored for a broad range of diseases by leveraging breakthroughs in genetic medicineand drug delivery technology.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Series C
United States, India, United Kingdom

Portfolio highlights

Wizard — Join the world's leading businesses using Wizard to sell, market, and engage their customers via text.
Immunomedics — Immunomedics is a biopharmaceutical company that specializes in developing monoclonal antibody-based products for the treatment of cancer and other serious diseases. Its corporate objective is to become a fully-integrated biopharmaceutical company. The company was founded in 1982 and headquartered in Morris Plains, New Jersey.
Willow — Willow is a female technology company that develops an in-bra wearable breast pump. Its breast pumps are cordless and spill-proof. It also tracks milk output through a mobile application along with an online portal, enabling mothers to pump anywhere without hassle. The company was founded in 2014 and is headquartered in Mountain View, California.

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Ireland, Singapore

Portfolio highlights

Jnana Therapeutics — Jnana was founded by leading academic scientists, drug developers and investors to develop medicines that transform the lives of patients.
Phreesia — Phreesia is a privately held company focused on patient check-in. The company replaces the outdated patient clipboard in physician offices with a free wireless touch screen and swipe card enabled PhreesiaPad. Phreesia automates the patient check-in process by collecting personal health information on the PhreesiaPad from the patient in a secure andHIPAA-compliant fashion. The product is designed to interface with physicians' existing and future technology and is compatible with electronic medical records (EMRs)Phreesia does not require any changes to the physician workflow and captures comprehensive patient information that can automatically be printed to reports for administrative and clinical staff. The company also improves the patient experience by better preparing them for their appointments, offering up-to-date health education relevant to their medical concerns, and enabling them to verify, rather than re-enter, information recorded at previous visits to the medical practice. The company draws on the expertise of a leading Medical Advisory Board and has initiated a series of patient care initiatives that concentrate on both wellness and disease prevention. The company is backed by premier venture capital firms and has received $13.25 million in financing to date.
Thirty Madison — Thirty Madison is a human-first healthcare company, powering access to affordable specialized healthcare through brands like Keeps and Cove.

Alumni Ventures is a venture capital firm that offers accredited investors access to diversified venture portfolios. The firm operates multiple funds, including alumni-focused and thematic funds, and co-invests alongside established venture firms. Investors can choose between fund-based investing or selecting individual deals. Alumni Venturesleverages a broad network to source capital, evaluate opportunities, and support portfolio companies. The firm manages a portfolio encompassing over 1,400 venture-backed companies across various sectors and stages.

Investment focus

Software, Artificial Intelligence, Information Technology
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

MEDIVIS — Medivis is a leader in AR for healthcare, using augmented reality and artificial intelligence to advance medical imaging and surgical precision.
ZZ Driggs — ZZ Driggs is an award-winning company reimagining how we furnish our lives for a new economy and a more sustainable future. We offer exceptional, sustainable, and ethically-made heirloom-quality furniture to rent, buy, or both, made by the best independent & emerging designers today.
Mythical Games — We are Mythical Games, a Venture-backed next-generation game technology company at the intersection of video games and economics led by industry veterans.

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
VeraDermics — VeraDermics Inc. is a dermatology pharmaceutical start-up, makers of WartPatch
PHȲND — PHȲND is a subscription-free cloud gaming platform that offers a way to discover, play, and socialize across a wide variety of games.

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

TandemAI — Streamline discovery with our integrated drug discovery platform, blending AI, physics-based tools, and wet lab for unparalleled innovation. Click now.
Epigenic Therapeutics — Epigenic Therapeutics is a biotech firm that offers gene editing therapy.
Pionyr Immunotherapeutics — Pionyr Immunotherapeutics is developing cancer immunotherapies that target the tumor microenvironment to enhance the body’s antitumor immunity. The company is exploiting novel target discovery and antibody generation platform technologies to create the next generation of immuno-oncology therapeutics. The company’s approach, Myeloid Tuning™, isdesigned to enhance the immune system’s anti-tumor response by altering the cellular infiltrate of the tumor microenvironment with high specificity.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
Sionna Therapeutics — Sionna Therapeutics is developing novel small molecule therapies to treat cystic fibrosis (CF).
Matchpoint Therapeutics — Matchpoint aims to discover and develop precision small molecules that harness the power of covalency to bring new possibilities to the treatment of serious immune disease and cancer.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

iRiva Medical — iRiva Medical is developing novel neuromodulation therapies to address unmet therapeutic requirements in large patient populations.
K36 Therapeutics — K36 Therapeutics mission to translate epigenetic modulation of oncogenic pathways into first-in-class small molecule therapies.
Canary Technologies — Use Canary to securely conduct contactless check-in and process credit card authorizations, contracts, and amenities online. Canary is the only PCI Level-1 Compliant solution for hotel authorizations. Schedule a demo today, and see how we can help your properties reduce chargebacks, save time, and improve the guest experience.

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Jounce Therapeutics — Concentra is a biosciences company.
Seaport Therapeutics — Seaport Therapeutics operates as a clinical stage biopharmaceutical company.

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, United Kingdom, Israel

Portfolio highlights

Hermeus — Hermeus is developing hypersonic aircraft to connect the world faster than ever before.
CarTrade — CarTrade - Buy and Sell Used Cars in India at right price. Find New Cars, car prices, upcoming cars and images. Read latest auto news, reviews and car comparisons.
Matrimony.com — Revolutionizing the Indian matrimonial industry with world class matchmaking and wedding planning services. Your search for the perfect match ends here!

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

FreeNav, Inc. — FreeNav is simplifying and standardizing the position tracking of procedural instrumentation for medical applications and procedures.
Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Canada, France

Portfolio highlights

Tr1x — Tr1x develops cellular therapies intended for the treatment of autoimmune disorders.
Affinia Therapeutics — Affinia Therapeutics is expanding what's possible in adeno-associated virus (AAV) gene therapy today and bringing transformative medicines for people.
Accipiter Biosciences — Accipiter Biosciences is a biotechnology company.

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

DropCap — DropCap is a tech-enabled rights agency (dropcap.com) and a global rights marketplace used by rights agents and acquisitions editors around the world to find great books (dropcapmarketplace.com). Our mission is to provide independent authors and publishers access to rights licensing opportunities and help indie books go global through foreignrights, audio, and film rights licensing.
Cylerity — Healthcare providers' financial stress is attributable in part to erratic cash flow. Cylerity saw healthcare providers struggling everyday with cash flow issues. Accounts receivables age 30, 60 or even 90 days, putting cash flow well past the need to pay operating expenses. Uncertainty associated with
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

Investment focus

Biotechnology, Health Care, Medical
Seed, Funding Round, Series A
United States, Canada

Portfolio highlights

KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies. they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.

Rock Health Capital is a full-service seed fund that invests in and supports startups working in digital health. The company invests in entrepreneurs working at the intersection of healthcare and technology. Rock Health Capital is a digital health-focused investment firm.

Investment focus

Health Care, Software, Medical
Seed, Series A, Series B
United States, Denmark

Portfolio highlights

Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
Ours Privacy — Ours Privacy provides a HIPAA-compliant CDP for secure, privacy-focused data management, analytics, and compliant advertising.

KdT Ventures is the standard for early-stage frontier science investing.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Israel, Germany

Portfolio highlights

Zag Bio — Zag Bio is harnessing the immune system in a whole new way by targeting the thymus to change treatment possibilities for millions of patients with autoimmune diseases.
PHNX Materials — PHNX Materials is a manufacturing company that specializes in turning waste into essential materials and reduce carbon emissions.
Faeth Therapeutics — Home | Faeth

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Clarifai — Clarifai is the leading Machine Learning, Computer Vision, NLP Platform. Label, train, deploy models on one AI platform for developers & data scientists.
Mendaera — Mendaera enables all healthcare providers to perform precise and consistent point-of-care interventions. Their platform combines real-time imaging, robotics, and artificial intelligence to aid physicians in image acquisition and interpretation.
Primer — At Primer, we help organizations make the best use of their investment in data, by using best-in-class machine learning and natural language processing technologies.

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

Standard BioTools — Standard BioTools delivers leading genomic and proteomic solutions. Discover CyTOF, Hyperion, and Biomark technologies for deep biological insights.
Rennovia — Rennovia, Inc. produces renewable chemicals. It offers adipic acids and adiponitrile for consumer-end products, including carpets, heat-resistant automotive parts, furniture, apparel, footwear, luggage, adhesives, and coatings. Rennovia was incorporated in 2009 and is based in Menlo Park, California.
Alexza Pharmaceuticals — Alexza Pharmaceuticals is an emerging specialty pharmaceutical company focused on the development and commercialization of novel, proprietary products for the treatment of acute and intermittent conditions. It was founded in 2001 and headquartered in Mountain View, California.

Investing in powerful, positive change that endures

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, India

Portfolio highlights

Arphie — AI-powered software to respond to RFPs, RFQs, questionnaires, and DDQs. Secure, live integrations with company-approved data. Win more, and save 80%+ time.
Doccla — We are a start-up. However, our management and advisors combine 100 years of experience in service delivery to large public and private healthcare operators in six European states, as well as several years in wearable device implementation in the global consumer space.
Backupify — Protection, restoration, security, and compliance for all your SaaS data.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Ritten — Ritten delivers a platform that helps clinicians and administrators provide personalized, data-informed care. The company's platform offers customized workflow configurations that help to deliver complex treatment consistently and compliantly, enabling clinicians and administrators to maintain a comprehensive patient record that tracks allaspects of a patient's care, including clinical notes, medications, and treatment plans, and deliver personalized, data-informed care.
ClearFeed — Conversational Support Platform on Slack
Citizen Health — Accelerate access to better treatments today, and create cures for tomorrow.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Green Park & Golf, built on over 50 years of operational and financial experience, seeks investment opportunities that offer above-market returns for its investors. Led by Clay Heighten, M.D., and Carl Soderstrom, the Firm delivers strategic solutions, financial backing and a reliable network to its portfolio companies. The Dallas-based Firm iscurrently looking for investment opportunities in medical-related start-ups.Dr. Heighten founded MedicalEdge Healthcare Group in 1993, and Mr. Soderstrom started PhyServe Physician Services in 1998 to administer the financial and operational needs of MedicalEdge. Together, the companies managed over 550 providers in five major markets. In 2011, the companies were sold to Texas Health Resources, a $3.8 billion health care system. That’s when Green Park & Golf was born.After earning his MBA at Southern Methodist University, Mr. Garcia joined them full-time in May 2011 to actively pursue new investment opportunities and monitor other investments in their portfolio. He has prior professional experience at FedEx, Bold Ventures, and Lone Star Investment Advisors.

Investment focus

Health Care, Medical, Biotechnology
Series A, Seed, Series B
United States, Israel, Sweden

Portfolio highlights

Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
Vellum Health — Vellum Health platform provides on-demand IV enablement & treatment optimized for provider organizations, payers, clinicians, and patients.
Affineon Health — Affineon is the AI inbox that saves provider time. We automatically handle normal and clinically insignificant lab results, and help providers get through abnormal lab results faster. Our AI automatically groups, analyzes, and trends lab results into a smart summary, including possible next steps and a complete patient note. We also route"noise" to staff, reducing the number of messages a physician needs to pay attention to by up to 30%. The result is 5+ hours saved per week per provider. Plus, Affineon tightly integrates with the EHR, so providers don’t need to change their existing workflow.

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

Investment focus

Software, Artificial Intelligence, Health Care
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Periodic Labs — Periodic Labs develops artificial intelligence systems that simulate and predict the properties of materials using machine learning. The company applies computational models to support the discovery and design of materials used in sectors such as energy, electronics, and infrastructure. It builds tools that aim to reduce the time and costassociated with traditional research and development processes. Periodic Labs uses AI to analyze large-scale scientific data and collaborates with academic and industry partners to support material science research.
Vectra AI — Vectra is the world leader in AI threat detection and response. The Cognito platform uses AI to detect attackers in real time and perform conclusive investigations.
Point One Navigation — Precise Positioning for the next generation of transportation. 10cm accuracy everywhere.

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

Investment focus

Health Care, Software, Biotechnology
Seed, Pre-Seed, Grant
United States, Canada, United Kingdom

Portfolio highlights

CoolTech — CoolTech develops transnasal cooling technology for non-invasive fever control and neuroprotection. Its CoolStat device is small, lightweight, and portable, able to move throughout the hospital with the patient. The device generates a source of filtered air that is delivered to the patient via a single-use air tubing set.
Tight & Right Hair Revolution — Tight and Right Hair Revolution’s fitness cap gives you the flexibility to work out without having to worry about your hair.
College of Southern Maryland Foundation — College of Southern Maryland Foundation fosters CSM's welfare, academic excellence, and development by procuring and administering funding.

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Ashby — Ashby is a developer of recruitment software used for high-growth companies. It develops usable, enterprise-grade employment software that enables company leaders, recruiters, and hiring managers to run their hiring process significantly better. It was founded in 2018 and is based in San Francisco, California.
Paxton — Regulatory Intelligence, with the speed of Generative AI.
Viridian Space — Viridian Space develops a propulsion technology intended to use oxygen to stay in ultra-low earth orbit. The company was founded in 2021 and is based in Culver City, California.

INVESTMENT ADVISORS TO THE FIRST VC FUND DEDICATED TO BIOTECH INVESTMENT MANAGER OF 9 SUBSEQUENT BIOTECH VC FUNDS

Investment focus

Biotechnology, Health Care, Medical
Series B, Series C, Series A
United States, Canada, Estonia

Portfolio highlights

Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

Investment focus

Health Care, Biotechnology, Software
Series A, Seed, Series B
United States, Cyprus, Ireland

Portfolio highlights

basys.ai — Reducing administrative burden in healthcare through secure, interpretable, and adaptive AI workflows. AI-Powered Prior Auth & Provider Workflow Automation. Streamline prior authorization with Basys AI-driven UMAI solutions for provider workflow automation. Ideal for health plans, RFPs, and digital transformation.
Autonomize AI — AI Copilots for Healthcare & Life Sciences. Empower knowledge workers, reduce administrative burden and improve health outcomes.
Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.

The Column Group (TCG) is a venture ecosystem dedicated to fueling scientific innovation in the life sciences industry.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Synthekine — Discovering, Developing and Commercializing the Next Generation of Selective Cytokine Therapeutics. We believe that cytokine therapeutics engineered to be selective can fundamentally change the treatment paradigm of cancer and inflammatory disease.
Atavistik Bio — Atavistik Bio is harnessing the power of protein-metabolite interactions to add a new lens to drug discovery.
Gritstone bio — Gritstone Oncology is a clinical-stage biotech company developing tumor-specific cancer immunotherapies to fight multiple cancer types. Its approach seeks to generate a therapeutic immune response by leveraging insights into the immune system’s ability to recognize and destroy tumor cells by targeting tumor-specific neoantigens. GritstoneOncology is headquartered in Emeryville, California, with key functions located in Cambridge, Massachusetts, and Pleasanton, California. It was founded in August 2015 and is listed on the Nasdaq Global Select Market under the ticker symbol GRTS.

GV supports innovative founders moving the world forward.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Seed
United States, United Kingdom, Switzerland

Portfolio highlights

Instawork — Instawork connects local businesses with proven hourly workers for temp, temp-to-hire shift work.
SingleStore — SingleStore is a provider of a database for operational analytics and cloud-native applications. It provides global enterprises with an intelligent database that works on any cloud on-premises or as a service runs transactions and analytics at the same time and lets clients promote their business through analytics and combine semi-structured datainto a consolidated big data platform.
Resistant AI — Resistant AI provides fraud detection and prevention in automated document processing workflows, transaction monitoring, and identities analysis.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Medical
Seed, Funding Round, Series A
United States, Canada, France

Portfolio highlights

ITeam — iTeam is transforming the way information technology (IT) and audio/video (A/V) installation services are packaged, sold and delivered through a new approach called Service-as-a-Product™ (SaaP™).
Monster Mosquito — Monster Mosquito focuses on providing all-natural mosquito sentry repellent systems for its clients. The company also develops a biodegradable compound insecticide to exterminate biting insects.Monster Mosquito uses mosquito mist systems, which contains pyrethrum, a natural mosquito killer made from chrysanthemums. The company was founded in 2002by Kemper Modlin and Leo Niekerk.It is based in Spring, Texas.
Davidson Instruments — Davidson has designed and developed innovative temperature-tolerant pressure measurement instrumentation that is rugged, immune to electromagnetic interference, and intrinsically-safe based on patented fiber optic sensing technology. The instrumentation has been proven through numerous installations with over one million hours of time inservice. Davidson's products include instruments for making high resolution static pressure measurements and others for making high speed dynamic pressure measurements.

Sanofi Ventures invests in top tier biotherapeutic and digital health entrepreneurs who focus on helping patients and transforming the healthcare system.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, United Kingdom, France

Portfolio highlights

Normunity — We create medicines that free normal immunity to defeat cancer using proprietary platforms that uncover novel immuno-oncology mechanisms.
T-Therapeutics — T-Therapeutics is a expertise in mouse genome engineering, deep expertise in biopharmaceutical drug development, single cell genomics, machine-learning and structural biology, anchored in a culture of creativity and collaboration. .
NextPoint Therapeutics — Nextpoint Therapeutics is creating precision therapeutics that combine direct tumor cell killing and immunomodulation in each single molecule for long-term cancer control, featuring first-in-class assets.

Martin Ventures provides capital, operational support and mentoring to assist entrepreneurs who want to be catalysts for change. Focusing primarily on health care and technology initiatives, Martin Ventures’ unique approach allows the leadership of our portfolio companies to more acutely focus on the optimal execution of their vision and strategywhile quickly scaling and growing their businesses into successful, profitable organizations.

Investment focus

Health Care, Medical, Hospital
Series A, Seed, Funding Round
United States

Portfolio highlights

BEKHealth — BEKHealth offers R&D platform solutions that will increase the efficiency and performance of clinical research operations.
ArcheHealth — ArcheHealth is enabling hospitals to operate more efficiently, cut expenses, and maintain expansion.
Harbor Health — Harbor Health is a multi-specialty clinic group that provides smarter health care using technology. The company co-creates a health path that is dedicated to knowing individuals' health goals with the guidance of specialists when needed. Harbor Health was founded in 2022 and is based in Austin, Texas.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

Granular — Corteva Agriscience software and digital solutions give the real-time, field-by-field information needed to maximize yield & manage input costs.
Databricks — Databricks offers a unified platform for data, analytics and AI. Build better AI with a data-centric approach. Simplify ETL, data warehousing, governance and AI on the Data Intelligence Platform.
Odyssey — Odyssey connects families with states to get access to funding from states to use with approved vendors to customize education for children who need it most.

SpringTide is a venture capital that provides investment in the health tech industry. The firm was founded in 2018 and is headquartered in Cambridge, Massachusetts, United States.

Investment focus

Health Care, Medical, Software
Seed, Series A, Funding Round
United States, Israel

Portfolio highlights

Nest Health — Nest Health is a primary care company that offers whole person, whole family care for families from birth through age five in urban areas. Nest offers primary and pediatric care for families, made affordable and convenient.
Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.
Paterna Biosciences — Male infertility care is lagging. Paterna is changing that with in vitro spermatogenesis. Explore our science and meet the team.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
Lab Symplified — Lab Symplified provides software for lab inventory, quality management, maintenance logs, and communication automation.
Naviday Health — Naviday Health is building personalized, AI-guided care pathways—starting with menopause—to help individuals confidently navigate complex health transitions. Our platform empowers daily decision-making through tailored insights, symptom tracking, and holistic support, bridging the gap between traditional care and real-world needs. We’re redefiningwhat it means to stay well every day.

Privately Held Companies

Investment focus

Health Care, Medical, Biotechnology
Series A, Series B, Series C
United States, Canada, Australia

Portfolio highlights

OutcomesAI — OutcomesAI operates as a healthcare company, that combines AI Voice Agents with licensed nurses to deliver safe, scalable care across health systems.
Apreo Health — Apreo Health is developer of medical apparatus designed for diagnosing or treating respiratory, pulmonary, and lung conditions.
ABK Biomedical — At ABK biomedical, we are focused on developing novel Y90 radioembolization treatment options for patients with hypervascular liver tumors

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Newfront — Modern insurance platform transforming risk management, employee experience, insurance, and retirement solutions with transparent data to lower your total cost of risk.
Nubank — Nubank issues, administrate, processes, and transfers payments related to post-paid credit cards and equity investment in other entities. It serves clients in Brazil. The company launched its proprietary loyalty rewards program ("Nubank Rewards"), as well as a digital account ("NuConta") that is already used by more than 17million people.Cristina Junqueira, David Velez, and Edward Wible founded EO2 Solucoes de Pagamento on May 6, 2013 that became Nubank in on June 25, 2013. It has its headquarters in São Paulo in Brazil.
Vest — Vest is an app-based brokerage that wants to provide Latin American savers with access to American assets that are differentiated by product, pricing, and content. Latin Americans are known for saving, but many prefer to do so in cash or in zero-interest savings accounts.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Software, Biotechnology
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Schola — Schola helps families find and enroll in the ideal PreK-12 schools.
Kanarys — Kanarys fuels progress towards more diverse, equitable and inclusive workplace cultures
Goalsetter — Goalsetter is a goal-based savings and gifting platform, made just for kids and powered by those who love them. It combines the best of goal-based savings platforms like Digit and Acorns with the best of gift-registries like Zola and Honeyfund, and in so doing, targets the millennial mom with a platform that enables families to contribute to kids’future goals instead of buying them more consumer goods. In turn, Goalsetter becomes a savings vehicle for kids, turning first-time savers into all-the-time savers and giving kids healthy financial habits that will last a lifetime.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Canada

Portfolio highlights

iRiva Medical — iRiva Medical is developing novel neuromodulation therapies to address unmet therapeutic requirements in large patient populations.
Viamet Pharmaceuticals — Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allowsthem to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.
TetraLogic Pharmaceuticals — TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. ItsNecrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

Investment focus

Biotechnology, Health Care, Therapeutics
Series B, Series C, Post-IPO Equity
United States, United Kingdom, Canada

Portfolio highlights

Star Therapeutics — Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.
Triana Biomedicines — Triana Biomedicines is building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. Triana’s drug discovery engine is powered by high- resolution structural insights, state-of-the-art in silico tools, and bespoke chemical libraries. The research team has validated thebest-in-class platform and initiated multiple programs across different disease areas.
Alchemab Therapeutics — Alchemab Therapeutics is developing natural protective antibodies designed to keep people free of hard-to-treat diseases. They are building their transformative engine to identify novel drug targets and develop a broad pipeline of novel antibody therapeutics for hard-to-treat cancers, neurodegenerative conditions, and infectious diseases.

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Switzerland, United Kingdom

Portfolio highlights

IFM Therapeutics — IFM Therapeutics is a provider of small molecule that module novel targets in the innate immune system. The company and its academic collaborators combine unparalleled expertise in innate immunity with seasoned drug discovery and development professionals. Its subsidiary IFM Due is focused on the discovery and developing antagonists of thecGAS/STING pathway for the treatment of inflammation, neuroinflammation, autoimmunity and cancer. IFM Discovery, a newly financed incubator entity within the IFM enterprise, is prosecuting a basket of genetically-validated targets as next-generation therapies for inflammation, neuroinflammation, autoimmunity and fibrosis
Callio Therapeutics — Callio Therapeutics focuses on developing next-generation, multi-payload antibody-drug conjugates to maximize therapeutic benefits.
Scorpion Therapeutics — We are developing drugs specifically designed to interact with validated cancer targets with greater selectivity and optimized pharmaceutical properties to improve their safety and efficacy.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series A, Series B, Series C
United States, Canada, United Kingdom

Portfolio highlights

Syndax Pharmaceuticals — Syndax Pharmaceuticals is a clinical-stage pharmaceutical company that focuses on an HDAC inhibitor for solid tumors and hematological tumors. It offers therapies to treat solid tumors and lung, breast, and hematological cancer. The company is developing axatilimab, a monoclonal antibody that blocks the colony-stimulating factor 1 (CSF-1) receptor,in development for chronic Graft versus Host Disease, and entinostat, a class I HDAC inhibitor.Syndax Pharmaceuticals pipeline includes and SNDX-5613, a highly selective inhibitor of the Menin–MLL binding interaction, in development for the treatment of patients with MLLr and NPM1 acute leukemias.
Portola Pharmaceuticals — As Alexion, AstraZeneca Rare Disease, we are delivering life-changing therapies to people living with rare diseases.
Rhythm Pharmaceuticals — Rhythm Pharmaceuticals is a global biopharmaceutical company committed to transforming the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, India

Portfolio highlights

Actively — A seamless booking assistant for your favorite fitness classes & wellness experiences
House Rx — House Rx is a health technology platform focused on improving affordability and patient access to specialty medications.
Troops — Never miss a revenue signal with Troops. Easily update Salesforce, HubSpot, Zendesk, and Jira right from Slack and Microsoft Teams. Get started for free.

Maverick Ventures is the venture arm of multi-billion dollar investment firm Maverick Capital. Combining the resources of a global firm with the benefits of an agile, focused team, Maverick Ventures supports entrepreneurs from seed through maturity. With over 30 years of early-stage investment experience, the Maverick Ventures team has funded morethan 100 companies in the healthcare, software and deep technology sectors. The highly-experienced team of operating executives and investors at Maverick Ventures generally lead rounds, take board seats and work with management to build successful enterprises.

Investment focus

Health Care, Medical, Biotechnology
Series A, Series C, Seed
United States, Israel, India

Portfolio highlights

Proximie — Proximie enables healthcare organizations, surgeons, and medical device companies to improve patient safety, scale training efforts, and accelerate device adoption, all while driving substantial savings in cost and time.
HumanFirst — HumanFirst enables better integration and analysis of digital health technologies in clinical trials.
Nourish — Achieve your desired health and wellness through personalized nutrition counseling. Nourish is the easiest way to find a registered dietitian and get it covered by your insurance. Find a dietitian today and start your telehealth appointments.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

doc-doc — Accede a los mejores especialistas en medicina, cuando y donde quieras.
Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
Biome Analytics — Providing doctors and hospitals precision insights needed to deliver better care at a lower cost. Cardiovascular program improvement, clinical performance applications, precision clinical and financial insights.

Building Companies that Shape the Future

Investment focus

Health Care, Biotechnology, Software
Series B, Series A, Series C
United States, Canada, Switzerland

Portfolio highlights

Oumi — Building truly open, reliable frontier AI.
Suki — Suki is an AI-powered voice assistant that lifts the administrative burden from clinicians, so they have time to focus on what matters - patient care.
GenLogs — Get ready to have your operations supercharged! Our real-time data on all trucks in America helps you find the right capacity at the right time.

SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

Investment focus

Software, Internet, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Telepatia — Telepatia is a health tech platform that utilizes artificial intelligence to support medical professionals.
Console — Console helps IT teams get to Inbox Zero. Auto-resolve over 50% of your support requests directly in Slack and Teams, using AI Agents that understand how your company does work.
Sage Care — Empowering smarter healthcare decisions with AI.

A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.

Investment focus

Software, Information Technology, Internet
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
PlanYear — Accessible Professional-Grade AI for Benefits Consultants
Parry Labs — Parry Labs is a solutions provider to the U.S. Department of Defense and commercial companies. Parry designs and deploys solutions ranging from mission computing, power systems, manned and unmanned system architectures, and RF solutions. Parry’s Stellar Relay products, is a full system suite of high-performance mission computing, ArtificialIntelligence (A.I.) processing, and cross-domain systems.

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