Top 50 Blockchain Startup Investors in United States (August 2026)

Portfolio highlights

• D3 — D3 - DNS Domains for Web3
• Stablecorp — Stablecorp is igniting a "step-function" improvement in financial services with our suite of products.
• Subzero Labs — Subzero Labs is developing Rialo, a developer-first Layer 1 blockchain built for internet-scale decentralized applications.

Portfolio highlights

• Yellow Card — Yellow Card is a licensed stablecoin payments infrastructure provider powering global money movement across USD and 50+ local currencies. Talk to us.
• Cambrian — The financial intelligence layer for agents & institutions. Cambrian's API helps you make the best financial decisions onchain. Testnet waitlist @ https://t.co/eohvz17ALp
• M0 —

Portfolio highlights

• Polkadot — Products for People.
• World Foundation — World is a new standard of trust for the internet - private proof of human, powerful financial infrastructure & the human-first experiences they enable.
• Solana Company — Building the Preeminent Solana Treasury $HSDT

Portfolio highlights

• TurboFlow — Trading, made simple. Everyone gets a seat at TurboFlow.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• RedotPay — Where Crypto Meets Real Life | Trusted by 8M+ | Accepted at 130M+ merchants | Pay with BTC, ETH, USDC, USDT & more
• Yellow Card — Yellow Card is a licensed stablecoin payments infrastructure provider powering global money movement across USD and 50+ local currencies. Talk to us.
• Fabric Cryptography — Building towards a trustless future with custom chips for advanced cryptography.

Portfolio highlights

• WINN.AI — WINN.AI helps revenue teams run better sales calls and win more deals by automating admin work and guiding reps live, during the call.
• Car Body Lab — The easy way, online.
• Perennial — Cloud Agronomics is the platform for soil carbon management.

Portfolio highlights

• Vangrid — Vangrid operates as a decentralized physical infrastructure network.
• Dow Protocol — An E-Commerce Financing RWA Platform on @BNBCHAIN, facilitating assets trusted by the world's largest banks. Lead invested by @mhventures @Maple_block
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• Mevvy Network — Where MEV Happens Discover, create, and capture MEV faster Backed by @multicoincap
• Inference — Inference infrastructure for AI-native teams
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• Almanak — Almanak is a decentralized finance (DeFi) smart agent platform that harnesses the power of artificial intelligence to automate, optimize, and intelligently manage a wide range of DeFi investment strategies. It enables users to create and deploy automated DeFi trading and risk-management strategies through coordinated AI agents. It provides anenvironment where AI handles strategy coding, backtesting across thousands of Monte Carlo simulations, optimization, risk monitoring, deployment via non-custodial Safe-based multisig accounts, and real-time performance monitoring with alerting capabilities. The platform supports seamless interaction with multiple blockchains and protocols via an LLM-powered interface.Almanak targets active DeFi participants, developers building financial applications, investment professionals, and users seeking automated portfolio insights. It emphasizes enhanced automation, continuous strategy execution, and adaptive automation driven by emerging AI techniques to respond to evolving market conditions.
• Open Campus — The Open Campus is a community-driven protocol that leverages the power of blockchain and invites all to build the future of education by putting the power of learning back in the hands of educators, students, and the community.

Portfolio highlights

• GTE — The Internet Exchange. Powered by Turbo, a high-throughput, low latency blockchain and exchange. Backed by top institutions, market makers, and you.
• Hylo — Liquidation-resistant leveraged tokens. Highest yielding stablecoin on Solana. Backed by @robotventures @colosseum @solanaventures
• Sprinter — Credit runs on Sprinter. The credit engine for the onchain economy

Portfolio highlights

• EDGE Markets — The Financial Platform for Smart Bettors
• Flying Tulip — Better Yield, Better UX
• LI.FI — Advanced Bridge & DEX Aggregation - Drive multichain strategies with cross-chain data messaging and get users from everywhere.

Portfolio highlights

• V12 — V12 is your security agent for mission critical code.
• Squads — Collaborative infrastructure for web3 native teams
• Legend. trade — Where traders become Legends.

Portfolio highlights

• 3Commas — 3Commas develops a crypto-asset management tool for tracking investments and exchanges in a unified platform. It provides access to a unified dashboard as the central hub for trading and portfolio management execution.
• Fuel Labs — At Fuel, we are building the fastest execution layer for the modular blockchain stack.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• Mudafy — Mudafy is a tech-enabled real estate broker for LatAm.
• Axis Robotics — AXIS ROBOTICS | Transferring Diverse Human Intelligence Into Robotic General Intelligence
• Hyperlane — Hyperlane is the platform for developers building the interchain universe

Portfolio highlights

• Crown — Crown issues BRLV, a real-backed stablecoin pegged to the Brazilian real, designed to maximize security and liquidity while ensuring compliance with institutional-grade regulations.
• Harmonic — Harmonic is a block building system to increase validator rewards.
• Global Token Exchange — The Internet Exchange. Powered by Turbo, a high-throughput, low latency blockchain and exchange. Backed by top institutions, market makers, and you.

Portfolio highlights

• Derivio — Be early. Trade smarter. One terminal.
• Tazapay — Experience Tazapay's best-in-class global payment solutions for businesses. Our extensive network supports cards, local payment options, and bank transfers in over 173 countries, ensuring seamless collections, secure holding, and efficient payouts worldwide.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.

Portfolio highlights

• Portal to Bitcoin — The only custody-less interoperability protocol for Bitcoin. Swap native BTC, Ordinals, Runes with L2s and L1s
• ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
• Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem

Portfolio highlights

• Mux — Mux helps teams ship high-performance and cost-effective video in minutes, not months. Build better video into anything from websites to platforms to AI workflows.
• Slack — Slack is a cloud-based communication and collaboration platform for teams. It allows users to exchange messages, share files, and integrate with various business tools and services. Slack is commonly used across various industries, from tech startups to large enterprises.
• Bigscreen — Founded by Darshan Shankar in 2014, Bigscreen is a venture-backed startup creating an immersive virtual reality platform that aims to revolutionize the way people work, play, hangout, and collaborate.Use cases of Bigscreen include both entertainment and productivity. Users love using Bigscreen as a "VR movie theater" to watch movies andTV shows. It's also used to play videogames, browse the web, and hangout with friends. It's can also be used for productivity as a tool for remote teams to collaborate together in virtual offices.Since the beta launch in March 2016, Bigscreen has become one of the most popular and highest rated VR apps on the Oculus Store and has an incredible 93% positive rating on Steam. Power users spend 20-30 hours per week in Bigscreen, making it one of the most widely used "killer apps" in the industry.Bigscreen is now the most popular non-gaming VR application in the world.Bigscreen is a fully distributed remote company with employees based around the world in the US & UK.

Portfolio highlights

• Fence — At Fence, we're transforming the way debt facilities are managed. We are the Operating System for your debt facility, reducing the amount of resources spent in back-office operations and letting teams focus on what matters.Our platform, built on blockchain technology, offers a Software as a Service (SaaS) solution that simplifies andautomate debt facility operations. Whether you're a capital provider or an asset originator, Fence leads you toward a smarter financial future.For capital providers, our platform enables internet-native debt solutions and real-time portfolio insights, enhancing your credit investment monitoring. With Fence, you stay ahead, making informed decisions for success. Asset originators benefit from enhanced capital efficiency and reduced operational costs, thanks to Fence's automation. We seamlessly integrate debt facilities into your tech stack and provide on-demand programmable debt, giving you unprecedented control over the capital you borrow.
• TBD — TBD is a forecasting market system that analyzes individual attitudes through integrating verifiable online polls.
• Blockworks — Blockworks is a financial media brand that delivers breaking news and premium insights about digital assets to millions of investors. Our editorial content, newsletters, podcasts and events provide investors with the critical analysis and information they need to make smarter decisions about digital assets.

Portfolio highlights

• Wizzwoods — 1st pixel farm game integrates interchain capabilities with a SocialFi twist.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• SuperGaming — At SuperGaming, we are putting India on the global gaming map.

Portfolio highlights

• Vorflux — Cloud agents that ship production code. An opinionated harness that runs the full SDLC on dedicated machines.
• BizScout — BizScout is an online platform of Off market deals for verified buyers and sellers.
• Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.

Portfolio highlights

• Sapiom — Where agents run
• Venice — Private & Unrestricted AI | https://t.co/iIt1pyF1TK
• Velocity — Velocity provides a unified platform for efficiently moving and managing funds across both traditional banks and blockchains.

Portfolio highlights

• Axis — Turning market inefficiencies into tokenized alpha. Backed by @galaxyhq, @FalconXGlobal, @okx.
• Zoo Finance — Zoo Finance is a pioneering DeFi protocol focused on unlocking liquidity from locked assets, empowering users to access capital more efficiently while maximizing the utility of their on-chain holdings.
• Hypernova — The onchain prop firm, built to back traders.

Portfolio highlights

• Rilla — Demonstrating 90% reduction in cost-to-serve for live-streaming, Rilla is rewiring the content economy, directing the value generated back to creators and their communities.By leveraging audience bandwidth and rewarding them with ownership in the network, the savings are equivalent to a free month subscription every year for a moderate level ofviewership.Founded by the technical founders behind Altered State Machine, acquired for 214m. Together for 5+ ventures, collectively raising 130m+ and valued at 1b+.
• Osmo — Osmo is a payment company that helps people to send and receive money immediately.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!

Portfolio highlights

• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• Flying Tulip — Better Yield, Better UX
• Hypernova — The onchain prop firm, built to back traders.

Portfolio highlights

• Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
• Aquantia — At Aquantia, all three elements are present in abundance. Aquantia benefits from team members with a depth of diverse technology development expertise, signal processing innovation and an adherence to lean and agile management practices. Their engineers were at the forefront ofthe Fast Ethernet and Gigabit Ethernet product deployments, and areamong the best in production silicon design.Meet their leadership team, or the board and investors to see their guidance, financial backing and the company they've built.
• Eightfold AI — Eightfold AI provides the most comprehensive AI recruiting and talent management solutions in the market. We make it easy for businesses to find, screen, and hire the best talent.

Portfolio highlights

• DarcMatter — DarcMatter is a fintech platform that provides cloud based infrastructure for asset managers to better manage, communicate and access investors. By utilizing proprietary structuring and technology, DarcMatter is able to provide a frictionless process for both investors and private issuers while remaining fully compliant of all current financialregulations.
• Chance Studios — Every Collection Starts With A Chance
• Chance Studios — Every Collection Starts With A Chance

Portfolio highlights

• Mecka AI — Mecka is the data and deployment layer for Physical AI.
• Spearbit — Spearbit connects independent security experts to Web3 projects that need them.The company offers a range of services, including expert-conducted security reviews and ongoing security reviews through retainer agreements. These services provide clients with an operational layer, freeing them from time-consuming administrative tasks and clientsourcing and due diligence.
• TVL Capital — TVL Capital is a financial infrastructure firm specialising in Chain Traded Products (CTPs).

Portfolio highlights

• Derivio — Be early. Trade smarter. One terminal.
• Watch.fun — Luxury watch drops. Win a Rolex for as little as $7, drops weekly. Certified by Wristcheck. Backed by @TheSpartanGroup @SolanaVentures @BigBrainVC and more...
• Solana Company — Building the Preeminent Solana Treasury $HSDT

Portfolio highlights

• SIBEX — Trade securely and directly between BTC and any ERC20 - Atomic cross-chain swaps. No Account Creation. No middlemen. Global Liquidity.
• OceanEx — OceanEx is one of the fastest-growing and reputable cryptocurrency exchange.
• BlockSeer — Raw data; real insight. Built for Bitcoin mining teams that want answers, not overhead. Free Bitcoin transaction explorer and wallet monitoring tool.

Portfolio highlights

• XFX — Powering international settlement
• Cyclops.io — Cyclops is the only crypto and stablecoin platform exclusively for payments companies. Cyclops enables payment service providers to accept crypto, do stablecoin settlement, and manage digital assets with enterprise-grade security. We provide PSPs, Card Networks, Acquirers, PayFacs and otherws with compliant crypto solutions without building in-house. Cyclops is chain agnostic, supporting Bitcoin, Ethereum, USDC, USDT, and multi-chain stablecoin settlement. White-label and turnkey offerings.
• Birdai Labs — Birdai operates at the base of the chain, measures where value leaks between an order and its fill, and is built to return it to the people who create the order flow.

Portfolio highlights

• Soter Insure — Reliable insurance for the digital asset ecosystem.
• Ethereum Institutional — Accelerating institutional adoption of Ethereum
• Digital Prime Technologies — Full-Service Institutional-Grade Prime Brokerage for Digital Asset Management. DLCC offers full-service Prime Brokerage solutions for digital assets. Our all-in-one user interface leverages both API and Saas product offerings to connect clients with a growing network of liquidity providers to transact, borrow, and lend digital assets, and managecollateral. Our product suite also offers traditional Prime Brokerage services, such as consultation and capital introduction.

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• NavigateAI — An AI copilot for every person in the field. NavigateAI upskills and coaches your team, runs real-time quality control, manages the project in the background, and provides expert knowledge, instantly.
• Vulcan — Frontier AI for government, law, and policy | backed by @ycombinator @generalcatalyst @cubitcapital

Portfolio highlights

• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• Saturn — Onchain Structured Digital Credit | Disciples of @Saylor | Incubated by @YZiLabs | Backed by @AD_VenturesX @SoraVentures @TheSpartanGroup
• THEA-AI — AI that amplifies human performance

Portfolio highlights

• Ornn AI, Inc — OranAI offers a comprehensive AI marketing solution that addresses operations, strategy, content production, and insights.OranAI concentrates on sectors including consumer electronics, fashion, FMCG, and cosmetics that have large budgets and quick decision-making cycles.
• Catena Labs — Catena is a product studio where we transform complex computing advancements into accessible, practical tools for users and developers. Leveraging AI and web3 technology our aim is to turn innovative ideas into real-world applications that are easy to use.
• Talos — Talos powers institutional access to the digital assets market - With full trade lifecycle coverage from price discovery through to execution and settlement.

Portfolio highlights

• IOTrader — Decentralized Trading Platform Predict Prices. Trade Futures. Win Big. Trade cryptocurrency futures with up to 20x leverage. https://t.co/2j18FWbdKc
• Tomoland — Tomoland is a social gaming platform where users create avatars, worlds, and multiplayer experiences.
• Midas — Structured Products, Onchain.

Portfolio highlights

• Packlane — Packlane makes it easy and affordable for small businesses to design and order custom boxes and packaging online. Through Packlane's online store, customers can apply their own branding and artwork to various packaging styles, get an instant quote, and preview their box designs in full 3D.
• Affinaquest — Kindsight's fundraising intelligence unlocks real-time insights to help you find donors, craft campaigns, and make more for your mission.
• CampusLogic — Fill prospective student pipeline and accelerate financial aid packages with clear cost transparency, AI-powered virtual advising, and matched scholarships.

Portfolio highlights

• Bio.xyz — Biotech's new financial layer.
• Recall Labs — Textile is building new digital experiences by focusing on user privacy, transparency, and decentralization.
• Blackbird — We believe the next great hospitality technology platform should connect restaurants and their customers directly, in meaningful and ongoing ways. Blackbird is founded by a team with a passion for restaurants and a track record of using technology to solve problems.

Portfolio highlights

• Alphea — ALPHEA is an AI-native execution OS that awakens intelligence across every surface.
• Dow Protocol — An E-Commerce Financing RWA Platform on @BNBCHAIN, facilitating assets trusted by the world's largest banks. Lead invested by @mhventures @Maple_block
• Fortune Protocol — Fortune Protocol brings the age- old tradition of fortune cookies to the modern prediction market.

Portfolio highlights

• Hylo — Liquidation-resistant leveraged tokens. Highest yielding stablecoin on Solana. Backed by @robotventures @colosseum @solanaventures
• Squads — Collaborative infrastructure for web3 native teams
• Exponent Finance — Outperform market rates with Solana's leading yield exchange. Community: https://t.co/tROuLHqyfC

Portfolio highlights

• BetHog — BetHog is a new crypto sports book that brings home the bacon.
• Trove — Trove Collectibles is a content and commerce platform focused on sports cards and collectibles.
• Kairos Labs — Kairos Labs is an Ethereum ecosystem interest rate swap protocol

Portfolio highlights

• Disgo — Disgo is Operator of a customer loyalty and engagement platform
• Trufin — This account has moved to @TruYields. Follow us there for updates.
• LIFE AI — LIFE AI (lifenetwork.ai) is an AI-powered blockchain platform for decentralized science in genomics, enabling users to own, control, and monetize personal genomic data while accelerating personalized medicine development 10x faster and cheaper.​ It provides clean, labeled genetic profiles via the LIFE Chain, LIFE App, and marketplace, supportingfeatures like DNA-powered LIFE IDs and Gene NFTs for secure, transparent data access.

Portfolio highlights

• XMTP — XMTP is a decentralized and quantum-resistant messaging protocol for builders.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.
• Superstate — Superstate is modernizing investing through tokenized financial products

Portfolio highlights

• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• Bundle — Bundle is the first networked rewards platform in the world, revolutionizing how companies interact with and reward their clients.Bundle provides companies with access to significantly more incentives than they could provide on their own by pooling brand incentive funds into common reward pools. Even though they only contribute a small portion ofthe total incentive value, brands can increase conversions.
• TrueNorth — The first Agentic Brokerage - build your own professional trading desk

Portfolio highlights

• Dataform — Develop and operationalize scalable data transformations pipelines in BigQuery using SQL.
• AIsa — Powering AI apps with one integration for premium APIs, data, compute, and payments. Backed by @AlibabaGroup @drapervc @Tribecap
• Databento — Databento provides real-time and historical market data APIs. Access data for equities, futures, options, and more with one integration. Sign up for $125 in free credits.

Portfolio highlights

• AltLayer — AltLayer is a system of highly scalable application-dedicated execution layers that derive security from an underlying L1/L2.
• Panoptic — The Panoptic protocol enables the minting, trading, and market-making of perpetual put and call options.
• Mask Network — Your Portal To The New, Open Internet.

Portfolio highlights

• EarnOS — EarnOS is the fully remote company that provides Global Ad & Payments Platform powered by Web3.
• KOR Protocol — KOR Protocol is a decentralized intellectual property (IP) infrastructure designed to empower creators, protect rights, and enable seamless collaboration and monetization of IP assets across various industries, including music, film, TV, gaming, and art. Backed by notable entities like Animoca Brands, Republic, Niantic, Sfermion, Solana, andprominent creators such as Black Mirror, Disclosure, deadmau5, and Richie Hawtin, KOR leverages blockchain, AI, and DeFi to offer a transparent, efficient, and scalable environment for IP expansion.
• Freehand — AI Teams for Complex Spend Management

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Portfolio highlights

• Row64 — Row64 turns the live data from your operations into action while it still matters.
• Last Energy — Last Energy develops and delivers micro modular nuclear power plants designed to provide decarbonized, reliable energy through a full-service delivery model that spans design, construction, and operations. The company offers factory-produced modular plants, like its 20 MWe PWR-20 units, that can be deployed rapidly to serve energy-intensiveindustrial customers and utilities with baseload electricity and heat. Its services include long-term power purchase agreements that eliminate upfront capital for customers while enabling flexible siting and minimal resource requirements. Last Energy’s solutions support both behind-the-meter applications for industries and grid-scale energy projects for broader power delivery. The company integrates established reactor technology with its delivery process to help clients access consistent, carbon-free energy.
• Commonwealth Fusion Systems — The fastest path to clean, limitless fusion energy.

Portfolio highlights

• Flood — Flood: The best DEX aggregator to optimize your trading. Experience top rates, zero gas fees, and full MEV protection. Trade across Arbitrum and Ethereum today.
• Stack — Recognize and reward the relationships that matter
• Reservoir — Infrastructure and APIs to bring efficient token markets to every chain, wallet, and app