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Top 50 Blockchain Startup Investors in United States in September 2025

Last updated: Sep 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Blockchain startups based in United states. We rank investors based on the number of investments they made in Blockchain companies from United states. We update this investor list every month.

Top 50 Blockchain Startup Investors in United States in September 2025

Investor	Blockchain United States investments
Polychain	66
Coinbase Ventures	63
Pantera Capital	61
Digital Currency Group	58
Blockchain Capital	48
Robot Ventures	38
Multicoin Capital	37
Electric Capital	36
Shima Capital	33
Animoca Brands	33
Balaji Srinivasan	32
CoinFund	32
Arrington XRP Capital	31
Fenbushi Capital	30
Paradigm	29
Framework Ventures	29
Andreessen Horowitz	28
Hack VC	28
Arrington XRP Capital	28
CMT Digital	28
Dragonfly	27
CMS Holdings	27
ParaFi Capital	26
Hashed	26
Lemniscap	26
Draper Associates	26
Alumni Ventures	25
The Spartan Group	25
Hashkey Exchange	25
SV Angel	24
Galaxy Digital	24
Solana Ventures	23
Big Brain Holdings	23
Blockchain Founders Fund	22
6th Man Ventures	22
a16z crypto	22
MH Ventures	22
Castle Island Ventures	21
Distributed Global	21
Tribe Capital	21
Mechanism Capital	21
Kenetic	21
Polygon	20
Wave Digital Assets	20
Wave Digital Assets	20
Alameda Research	20
Dapper Labs	20
Polygon	20
Slow Ventures	19
Lightspeed Venture Partners	19

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Investor list

The emergence of bitcoin and subsequent blockchain technologies has generated a new digital asset class in which scarcity is based on mathematical properties. Through cryptographic verification and game-theoretic equilibrium, blockchain-based digital assets can be created, issued, and transmitted using the software. Polychain Capital is committedto exceptional returns for investors through actively managed portfolios of these blockchain assets.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, Switzerland

Portfolio highlights

Digital Asset — As leaders in blockchain technology, Digital Asset empowers customers with Daml, the leading platform for multi-party applications; an innovative smart contract language and Canton, our privacy-enabled distributed ledger technology.
180 Life Sciences — Born from Ethereum. Built for everyone
Heritage Distilling — Heritage Distilling Co. (HDC) is a craft distillery based in Gig Harbor, Washington. HDC is the most awarded craft distillery in North America by the American Distilling Institute 10 years in a row. We pour a little of our heart into every batch of spirits we make.

Coinbase Ventures is an investment arm of Coinbase that aims to invest in seed-stage cryptocurrency and blockchain startups. The company was founded in 2018 and is based in San Francisco, California, United States.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, India

Portfolio highlights

Legion — Legion makes on-chain fundraising accessible to ordinary investors by ensuring regulatory compliance and investor accountability.
o1.exchange — Building the next generation NASDAQ and AI Religion to bring human beings together with social and financial AI Agents @ Cohuman Labs. Trillion Dollar Market Cap. Backed by a16z games (SPEEDRUN), and many other top investors. AI + Web3 + Infra + Consumer
Mesh — Mesh enables safer, easier crypto transfers and payments from 300+ leading exchanges and wallets, all without leaving your platform

Pantera Capital is an investment firm focused exclusively on Bitcoin, other digital currencies, and companies in the space. The company believes that Bitcoin has the potential to transform the way people use money and that it will do for payments what the Internet has done for communications and commerce.Until 2014, Pantera focused on globalmacro hedge fund investments. The firm was founded in 2003 by Dan Morehead, who was a chief financial officer and head of Macro Trading at Tiger Management. The firm has since shifted its investment advisory services to focus exclusively on Bitcoin, other digital currencies, and companies in the space.Shareholders include Benchmark, Fortress Investment Group, and Ribbit Capital.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

M0 — M^0 is money middleware for the digital age. It is a decentralized, on-chain protocol, as well as a corresponding set of off-chain standards and APIs, that allows holders of high-quality eligible collateral to participate in the issuance of a fungible cryptodollar. With M^0, any number of institutions around the world can tap on turnkey middlewareto become their own cryptodollar issuer, upgrading their money tech stack to the digital age.
aPriori — aPriori is a monad-native MEV infrastructure and liquid staking mechanism developed for parallel executions.
OpenMind — OpenMind is a software company that develops an operating system for robots and intelligent machines.

We are the capital engine supporting emerging talent & crypto technology. On its mission to accelerate the development of a better financial system.

Investment focus

Blockchain, Cryptocurrency, FinTech
Seed, Series A, Funding Round
United States, United Kingdom, Singapore

Portfolio highlights

Munify — Fast, secure, and cost-efficient cross-border payments powered by stablecoins. Send and receive money globally without delays, high fees, or the complexity
Manifold Labs — Manifold Labs is a decentralized AI infrastructure company.
Doppler Finance — Doppler Finance is a yield-earning platform that unlock earning opportunities within the XRPL ecosystem

Partners to crypto builders since 2013.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, United Kingdom, Singapore

Portfolio highlights

Levr Bet — LEVR provides users with a decentralized sports betting platform that combines leveraged DeFi with traditional sports betting.
Tally — Tally is a DAO operations platform. DAOs use Tally to create and pass proposals, enable delegation, and power voting.
Camp Network — Camp Network is a purpose-built Layer 1 blockchain to power AI agents.

Robots Never Sleep

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Pre-Seed
United States, Canada, Singapore

Portfolio highlights

Defx — Defx is a non-custodial perps venue. We're built on Arbitrum, and will be coming to Solana very soon.
MagicBlock — MagicBlock Labs is a gaming and technology firm that creates infrastructure for fully on-chain games.
Wildcat Labs — Wildcat Labs provides on-chain credit and grants access to a detailed view of all market parameters and logs for real-time monitoring.

Multicoin Capital is a thesis-driven investment firm that invests in cryptocurrencies, tokens, and blockchain companies reshaping trillion-dollar markets.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, Switzerland

Portfolio highlights

Yield.xyz — Yield.xyz is the all-in-one Web3 yield API. Staking, DeFi, stablecoins: full data access, plug-and-play UX, up to 2.8x more revenue.
Arch — The pioneering network for building bridgeless apps directly on Bitcoin. Arch makes it easy to deploy interoperable smart contract-like programs on the L1, without fracturing liquidity or taking on bridge risk.
DoubleZero — DoubleZero is developing a global fiber network intended for high-performance distributed systems and blockchains. It seeks to enhance blockchain performance by establishing a dedicated physical infrastructure layer for communication.

Building the future of Web3. We invest in the next generation of iconic founders.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Hyperbeat — Hyperbeat is a native protocol built specifically for the Hyperliquid ecosystem, designed to enhance scalability, efficiency, and overall performance across the network.
Aven — Inventing new ways to save people money
Etherealize — Explore Etherealize: Your gateway to Ethereum-powered financial innovation. Discover research, insights, and products shaping the future of finance.

Shima Capital is an investment fund that focuses on supporting blockchain startups. The firm is headquartered in San Francisco, California, United States.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

Almanak — Almanak is a decentralized finance (DeFi) smart agent platform that harnesses the power of artificial intelligence to automate, optimize, and intelligently manage a wide range of DeFi investment strategies. It enables users to create and deploy automated DeFi trading and risk-management strategies through coordinated AI agents. It provides anenvironment where AI handles strategy coding, backtesting across thousands of Monte Carlo simulations, optimization, risk monitoring, deployment via non-custodial Safe-based multisig accounts, and real-time performance monitoring with alerting capabilities. The platform supports seamless interaction with multiple blockchains and protocols via an LLM-powered interface.Almanak targets active DeFi participants, developers building financial applications, investment professionals, and users seeking automated portfolio insights. It emphasizes enhanced automation, continuous strategy execution, and adaptive automation driven by emerging AI techniques to respond to evolving market conditions.
Goldilocks DAO — Goldilocks is a Decentralized Autonomous Organization (DAO) dedicated to creating custom defi infrastructure for Berachain. The Goldilocks Protocol is comprised of three primary components: Goldiswap, Goldilend, Goldivaults.
Distinct Possibility Studios — Distinct Possibility Studios operates as a game development studio. Distinct Possibility Studios is an indie game studio led by MMO and FPS veterans.

Animoca Brands is a metaverse and gaming venture capital firm that focuses on driving digital property rights to gamers and internet users through NFTs. It utilizes gamification and blockchain to develop and market a portfolio of mobile applications, games, and additional products oriented to educational learning to ensure transparency, security,and new business models.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

HackQuest — HackQuest is a Multichain Web3 developer and founder platform, with education, community events, hackathons, and accelerators at its core. HackQuest helps over 20 leading ecosystems such as Mantle, Solana, Arbitrum, and Linea onboard quality developers and supports developers to jumpstart their careers in Web3.
Quack AI — Quack AI is an artificial intelligence governance Layer for Web3.
VERB Technology Company — VERB Technology Company is a software-as-a-Service, or SaaS, applications platform developer. Its platform is comprised of sales enablement business software products marketed on a subscription basis. The applications are available in both mobile and desktop versions. It includes verbCRM, Customer Relationship Management application, verbLEARN,Learning Management System application, and verbLIVE, its Live Broadcast Video Webinar application.

Balaji S. Srinivasan is the Co-Founder and Board Member of Coin Center. He was the CTO of Coinbase and cofounder of Counsyl, Earn, Teleport, and Coin Center. He was previously CEO at Earn.com, which was recently sold to Coinbase. Prior to taking the CEO role at Earn.com, Dr. Srinivasan was a General Partner at Andreessen Horowitz. Prior to joininga16z, he was the co-founder and CTO of Founders Fund-backed Counsyl, where he won the Wall Street Journal Innovation Award for Medicine and was named to the MIT TR35. Dr. Srinivasan holds a BS, MS, and PhD in Electrical Engineering and an MS in Chemical Engineering from Stanford University. He also teaches the occasional class at Stanford, including an online MOOC in 2013 which reached 250,000+ students worldwide.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, India, Singapore

Portfolio highlights

Catena Labs — Catena is a product studio where we transform complex computing advancements into accessible, practical tools for users and developers. Leveraging AI and web3 technology our aim is to turn innovative ideas into real-world applications that are easy to use.
Paradigm — The AI-powered way to do spreadsheet work. Set up, edit, populate, and analyze sheets with assistant. Enrich empty cells with data from trusted sources.
Inversion — Inversion is a technology-first investment company that acquires and transforms legacy businesses with blockchain technology.

CoinFund is where web3 capable meets web3 capital: cryptonative technologists who invest in the future before it's a trend.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, United Kingdom, Singapore

Portfolio highlights

Irys — Irys is a Layer-1 blockchain combining low-cost storage, verifiable compute, and AI coordination in a single network.
MEI Pharma — MEI Pharma, Inc. (Nasdaq: MEIP) is a San Diego-based oncology company focused on the clinical development of novel therapies for cancer. The Company’s clinical development pipeline includes lead drug candidate Pracinostat, a potential best-in-class, oral histone deacetylase (HDAC) inhibitor. Pracinostat has been tested in more than 150 patients inmultiple Phase I and exploratory Phase II clinical trials, including advanced hematologic malignancies such as myelodysplastic syndrome, acute myeloid leukemia and myelofibrosis. The Company expects to initiate a randomized Phase II trial of Pracinostat in combination with standard-of-care in at least one hematologic malignancy toward the middle of 2013. In addition, MEI Pharma is developing two drug candidates derived from its isoflavone-based technology platform, ME-143 and ME-344. Results from a Phase I trial of intravenous ME-143 in heavily treated patients with solid refractory tumors were presented at the American Society of Clinical Oncology Annual Meeting in June 2012. A Phase I clinical trial of intravenous ME-344 in patients with solid refractory tumors is ongoing.
Dakota Ridge — Dakota Ridge is a technology company specializing in the development of a secure, enterprise-grade banking infrastructure designed specifically for cryptocurrency businesses. The platform offers advanced storage solutions and a comprehensive suite of tools that support both fiat and digital assets. I

Arrington Capital is a thesis-driven firm investing in digital assets and Web3 since 2017

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Series A
United States, Singapore, South Korea

Portfolio highlights

ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem
QED Protocol — A trustless, scalable, decentralized compute protocol for a fairer internet focused on user privacy and platform transparency.

Fenbushi Capital is the first and most active blockchain-focused venture capital firm in Asia. Founded in Shanghai in 2015 by veterans across both blockchain and traditional financial industries, it has to date supported over 80 leading projects across 4 continents leveraging blockchain technology to reshape myriad industries such as finance,healthcare, supply chain, and consumer goods. Fenbushi’s mission is to drive healthy and sustainable growth in the global blockchain ecosystem, and actively works as a long-term strategic partner to its portfolio projects.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, China

Portfolio highlights

Irreducible — Ulvetanna provides fast and cost-effective computation of zero-knowledge succinct proofs. We operate FPGA clusters tailor-made for ZKP computation at scale, purpose-built to support Layer-1 and Layer-2 blockchain protocols.
MetaEra — MetaEra is a one-stop resource aggregator for Web3.0. Meta Era focuses on blockchain and metaverse exploration, pursuing professional, thorough, and reliable information and data.
Chronicle Labs — Evolving from the Oracle Core Unit at MakerDAO, Chronicle Protocol was created by the unit’s development team. Although the Oracles that underpinned Chronicle Protocol had been securing MakerDAO’s $10B+ collateral since 2016, the technology and its unique innovations weren’t available outside of Maker’s portfolio.In 2021, the team receivedsupport from MakerDAO to spin out the proprietary technology and form a new entity and brand. Chronicle Protocol was born.Chronicle continues to service MakerDAO and now, for the first time, is rolling out its on-chain Oracle services to support the wider Web3 world.Chronicle Protocol has been developed to solve many of the current pain points of on-chain Oracles and DeFi. On-chain Oracles, particularly on computationally expensive blockchains such as Ethereum, are bottlenecking the development of DeFi with an exorbitant cost of service and a lack of feasible scalability. Through developing a proprietary solution called Scribe, the team at Chronicle has built a blockchain-agnostic, ubiquitously accessible, scalable, end-to-end verifiable, and decentralized Oracle. The protocol’s unique architecture enables an ecosystem that delivers 100% decentralization and transparency. Every byte of data can be traced back to each Feed’s original data source queries, and new Oracles can be deployed (and updated) with the click of a button on the Chronicle Dashboard.Inspired by Ancient Greece’s Herodotus (the Father of History), Chronicle Protocol aims to be the world’s first open and verifiable data chronicler. Transparency, democracy, and accessibility are the columns on which Chronicle has built its temple, and industry-leading scalability, integration, and security are the features that power the protocol.Verifiable data, accessible to all - delivered securely and affordably.

Paradigm is an investment firm focused on supporting the great crypto/Web3 companies and protocols of tomorrow. Our approach is flexible, long term, multi-stage, and global. We often get involved at the earliest stages of formation and support our portfolio with additional capital over time.

Investment focus

Cryptocurrency, Blockchain, FinTech
Series A, Seed, Series B
United States, United Kingdom, Cayman Islands

Portfolio highlights

Plural Energy — Plural Energy connects institutional investors with high-quality renewable energy assets overlooked by traditional finance. Access middle-market clean infrastructure with competitive yields, tax benefits, and impact while advancing the energy transition.
Etherealize — Explore Etherealize: Your gateway to Ethereum-powered financial innovation. Discover research, insights, and products shaping the future of finance.
Plural Energy — Plural Energy is a platform for renewable energy assets available to more investors from fund and asset managers to alternative retail investors and retirement savers.

A crypto venture firm that builds with our founders.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, Australia

Portfolio highlights

W3.io — W3.io is a web3 company dedicated to driving Web3 adoption through open protocols and standards.
USD.AI — USD.AI is a stablecoin protocol at the intersection of blockchain and artificial intelligence.
Perle AI — Kiva AI is a platform designed to supply high-quality and compliant data solutions at scale to create specialized AI applications in domains such as healthcare, finance, and law.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

Lead — Lead Bank is a community-minded, independent commercial bank with a national client base recognized for its imaginative approach to community banking.
Databricks — Databricks offers a unified platform for data, analytics and AI. Build better AI with a data-centric approach. Simplify ETL, data warehousing, governance and AI on the Data Intelligence Platform.
Allocate — Allocate is the operating system for private market alternatives investing

Hack VC is a web3 venture capital firm.

Investment focus

Blockchain, Software, Cryptocurrency
Seed, Series A, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

TAC — TAC is a TON network extension that allows the EVM community to access Telegram users, and it enables Ton wallet holders to easily interact with EVM dApps deployed on TAC.
Donut — Donut is the first crypto agentic browser that uses the finest crypto in-domain model and a swarm of browsing agents.
Stable — Stable is a blockchain infrastructure designed to facilitate compliant and predictable USDT transactions.

Arrington Capital is a thesis-driven firm investing in digital assets and Web3 since 2017

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Series A
United States, Singapore, South Korea

Portfolio highlights

ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem
QED Protocol — A trustless, scalable, decentralized compute protocol for a fairer internet focused on user privacy and platform transparency.

An exciting new iteration of our website is coming soon. CMT Digital is a blockchain and digital assets focused subsidiary of the CMT Group, a 24 year-old trading and investments firm. The CMT Group has operated as a valued partner to entrepreneurs, traders, and technologists

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Defx — Defx is a non-custodial perps venue. We're built on Arbitrum, and will be coming to Solana very soon.
Synervest — Synervest Group is a fintech platform offering regulated cross-border trading, payments, and financial technology infrastructure for institutional clients, for both B2B and B2C models. It's headquartered in ADGM and operates in Europe and the Middle East, with offices in the UK and Cyprus.
Cooking.City — Cooking.city is a Solana ecosystem token issuance platform that focuses on making token launches transparent and equal for all participants.

A cross-border cryptoasset investment firm. Global from day one.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Series A
United States, Singapore, Hong Kong

Portfolio highlights

USD.AI — USD.AI is a stablecoin protocol at the intersection of blockchain and artificial intelligence.
Rain — Rain is a vertically integrated issuing partner for global platforms. Enabling innovative financial products through modern APIs, flexible infrastructure, supporting electronic and digital money. Launch a card program in days not months.
Inversion — Inversion is a technology-first investment company that acquires and transforms legacy businesses with blockchain technology.

CMS is a principal investment company that focuses on investing in the crypto-asset ecosystem. The firm plans to invest in both liquid and illiquid crypto tokens, as well as equity interests in select businesses.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

Perpl — Perpl improves financial systems by creating a clear pricing engine on an effective blockchain.
Rover — Rover is a liquid staking protocol on Botanix that exchanges Bitcoin for rovBTC.
Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

ParaFi Capital is an alternative investment firm focused on blockchain and decentralized finance markets.

Investment focus

Blockchain, Cryptocurrency, FinTech
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Inversion — Inversion is a technology-first investment company that acquires and transforms legacy businesses with blockchain technology.
VERB Technology Company — VERB Technology Company is a software-as-a-Service, or SaaS, applications platform developer. Its platform is comprised of sales enablement business software products marketed on a subscription basis. The applications are available in both mobile and desktop versions. It includes verbCRM, Customer Relationship Management application, verbLEARN,Learning Management System application, and verbLIVE, its Live Broadcast Video Webinar application.
Mill City Venture III — Building the world's leading Sui treasury.

Hashed is a global, early stage venture fund focused on backing founders who are pioneering the future of blockchain and cryptocurrency. Hashed is based in Seoul and San Francisco.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, South Korea, Singapore

Portfolio highlights

Subzero Labs — Subzero Labs is developing Rialo, a developer-first Layer 1 blockchain built for internet-scale decentralized applications.
Heritage Distilling — Heritage Distilling Co. (HDC) is a craft distillery based in Gig Harbor, Washington. HDC is the most awarded craft distillery in North America by the American Distilling Institute 10 years in a row. We pour a little of our heart into every batch of spirits we make.
Distinct Possibility Studios — Distinct Possibility Studios operates as a game development studio. Distinct Possibility Studios is an indie game studio led by MMO and FPS veterans.

Lemniscap is an investment firm specialising in investments in emerging cryptoassets and blockchain startups.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Pre-Seed
United States, United Kingdom, France

Portfolio highlights

Memes Lab — Memes Lab is a multi-level meme infrastructure on TON, integrated with Telegram Stars, which allows users to purchase meme coins without a wallet.
Pulse — Pulse is a developer of an all-in-one health and wellness platform designed to integrate a wearable gadget and a fitness tracking software.
DeCharge Network — DeCharge Network lays the groundwork for a global energy network that will power automobiles, drones, and future technology.

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

Investment focus

Software, FinTech, Information Technology
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Neurvona — AI Digital Twin Personas
MIDL — MIDL is a digital finance company that offers EVM compatibility, functionality of Ethereum dApps to Bitcoin users.
Decile Group — Discover how to launch a VC fund instantly with top managers. Join us to fund great companies changing the world. Start your journey now!

Alumni Ventures Group provides high-quality, diversified venture portfolios to individual investors who previously haven't had access to VC.It helps accredited alums from top entrepreneurial schools invest together in the ventures of fellow alums. The firm backs companies with an alumni connection and an institutional lead investor withexpertise in the space. AVG also offers focused funds that allow any accredited investor access to a venture portfolio, diversified by type, sector, stage, and geography.Beth Obermiller, Michael Madden, and Mike Collins co-founded the firm in Manchester, New Hampshire in 2013.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Kognitos — Kognitos is in stealth mode.
CRED — Compare millions of commercial data points and uncover unique and personalised opportunities for your brand.
Spekter Games — Spekter Games offers well-tested free-to-play Web2 mobile games that have been improved with a skillfully designed Web3 incentive layer, as well as chat-based super apps.

We advise, invest and build with the best entrepreneurs in Web3.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
Planetarium — Planetarium is a company that wants to return the sovereignty of online games to users through blockchain technology.
Tarta Labs — Tarta Labs is dedicated to building a next-generation anime IP ecosystem and aims to innovate within the anime gaming space by blending engaging narratives, high-quality visuals, and community-driven gameplay experiences.

Hashkey they offers investment opportunities and solutions to institutions, family offices, funds, and professional accredited investors across the digital asset and blockchain ecosystem.

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Series A
United States, Singapore, Switzerland

Portfolio highlights

AltLayer — AltLayer is a system of highly scalable application-dedicated execution layers that derive security from an underlying L1/L2.
Supra — Supra is the world's highest-performing, fully vertically integrated L1 blockchain, and it's about to change everything.
Panoptic — The Panoptic protocol enables the minting, trading, and market-making of perpetual put and call options.

SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

Investment focus

Software, Internet, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

ai.work — Amplify your team with intelligent AI Workers connected to your systems, knowledge, and policies - built to work the ticket queues, automate the repetitive tasks, and get things done - lightning fast.
TravoAI — Mobile app for annotating PDF worksheets with real-time AI tutoring. Made by Stanford students.
Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.

Galaxy is a digital asset and blockchain leader helping institutions, startups, and individuals shape a changing economy.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Series A, Seed, Funding Round
United States, United Kingdom, United Arab Emirates

Portfolio highlights

Forward Industries — Forward is a fully integrated design, development, and manufacturing solution provider to top tier medical and technology customers worldwide. Through its acquisition of Intelligent Product Solutions (“IPS”), the Company has expanded its ability to design and develop solutions for our existing multinational client base and expand beyond thediabetic product line into a variety of industries with a full spectrum of hardware and software product design and engineering services. In addition to our existing design and distribution of carry and protective solutions, primarily for handheld electronic devices, we are now a one-stop-shop for design, development and manufacturing solutions serving a wide range of clients in the industrial, commercial and consumer industries.
Mill City Venture III — Building the world's leading Sui treasury.
Fundamental Global — FG Nexus is building a U.S. public company dedicated to Ethereum accumulation and on-chain yield generation, a capital markets vehicle engineered for one of the most important digital assets of this era.

Solana Ventures' mission is to accelerate the growth of the Solana blockchain and adjacent ecosystems by providing capital to the most promising teams building in the crypto ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Series A, Funding Round
United States, Singapore, Australia

Portfolio highlights

Vanish Trade — Vanish Trade is a Solana-based trading platform focused on anonymity.
FrodoBots Lab — FrodoBots Lab is pioneering advancements in Embodied AI research at the intersection of crypto and gaming.
Reflect money — Reflect enables the issuance and redemption of decentralized strategy-backed stablecoins on SVM-based networks.

Big Brain Holdings is Focused on Investing in Solana projects that have strong potential.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Pre-Seed, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Upexi — Upexi is a multi-faceted brand owner that focuses on direct-to-consumer and Amazon brands. The company pursues organic growth for its present brands while operating in sectors with high growth trends. The objective of Upexi is to keep gathering consumer information and develop a sizable client database across all markets we serve.
Reflect money — Reflect enables the issuance and redemption of decentralized strategy-backed stablecoins on SVM-based networks.
Mill City Venture III — Building the world's leading Sui treasury.

We Focus Exclusively On Adding Value To Blockchain & Emerging Technology Projects With Real World Applications.

Investment focus

Blockchain, Cryptocurrency, FinTech
Seed, Pre-Seed, Funding Round
United States, United Kingdom, Singapore

Portfolio highlights

Freename — Redefining Web3 Naming System. Web3 Registrar: custom TLDs and Domains
Metafide — Metafide offers AI-driven trading solutions and Web3 asset analysis for financial entities.
Velvet Capital — Velvet Capital is a DeFi operating system that helps launch and manage on-chain funds and structured products. Velvet Capital offers its users a way to gain exposure to digital assets.

6th Man Ventures is an early stage crypto VC firm investing in web3 applications & infrastructure6MV was born from a love of web3 in practice and principle, founded and run by a group who both see the potential and actively work to bring projects to life every day. That makes us incredible partners to have on your journey.6th Man Ventureswas established in March 2021 in New York, United States.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

Shinami — Tools to build the next wave of decentralized applications
Football.Fun — football. Fun is a fantasy football platform that combines the dynamics of cryptocurrency markets with football player trading.
August — A new standard for on-chain finance.

A16z crypto is a $300M venture fund that will invest in crypto companies and protocols. The company's fund is designed to include features of traditional venture capital, updated to the modern crypto world.

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Pre-Seed, Series A
United States, United Kingdom, Canada

Portfolio highlights

Intent Inc — GroupUltra is a platform that allows users to program their groups and design their communities.
Reflect money — Reflect enables the issuance and redemption of decentralized strategy-backed stablecoins on SVM-based networks.
Heritage Distilling — Heritage Distilling Co. (HDC) is a craft distillery based in Gig Harbor, Washington. HDC is the most awarded craft distillery in North America by the American Distilling Institute 10 years in a row. We pour a little of our heart into every batch of spirits we make.

MH Ventures is a world class community-backed Venture Capital investing in top blockchain projects of the future

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Funding Round, Pre-Seed
United States, Singapore, United Arab Emirates

Portfolio highlights

HeyElsa — Harness the power of AI in Crypto with Elsa, your crypto co-pilot. Uncover opportunities, trade smarter, and maximize returns, all with unparalleled ease and safety.
PublicAI — PublicAI is a Web3 distributed AI training network that helps people to earn rewards by contributing data work.
Cold River Games — Cold River Games is a Swedish game studio currently developing the ARPG Crystalfall.

Castle Island Ventures is a Cambridge, MA based early stage venture firm investing in startups building in the public blockchain industry.

Investment focus

Blockchain, Cryptocurrency, FinTech
Seed, Series A, Series B
United States, India, China

Portfolio highlights

Stable — Stable is a blockchain infrastructure designed to facilitate compliant and predictable USDT transactions.
Pear Protocol — The Home of Pair Trading.
Build on Bitcoin — BOB (Build on Bitcoin) is the first Bitcoin L2 with full EVM compatibility

Distributed Global is an investment firm focused on the blockchain and digital asset ecosystem.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Switzerland, Germany

Portfolio highlights

Nillion — The Secure Processing Layer of Web3
Huma Finance — Huma is an Income backed DeFi.
Fogo Digital — Defying physics to achieve real-time experiences at scale. | SVM Layer 1 | Pure Firedancer Client | Institutional-Grade Finance

Tribe Capital is a top-quartile venture capital firm focused on capturing a perpetual edge in venture and crypto using data science. The team is made up of investors, engineers and scientists who use artificial intelligence (“AI”) and data science to model venture-backed private companies.Beyond investment capital, Tribe deploys these AI tools toseparate signal from noise, helping our companies understand their businesses better. Our data-informed strategy includes an underwriting infrastructure and a quantitative analysis tool called the “Magic 8-ball.” We leverage these tools to provide deep insight on factors driving growth and how to accelerate sustainable growth, honed through years of developing similar products at major tech and finance players like Lyft, Yahoo, Facebook, and Bridgewater Associates. Our team uses these tools to measure quantitative product-market fit, so we can more effectively assess and accelerate what Tribe refers to as “N-of-1” companies - companies with the potential to be 10-100x growth opportunities, while minimizing loss ratio by a large degree. Tribe Capital has $1.6 billion in assets under management and has made notable investments in Apollo.io, Carta, Docker, Kraken, Instabase, Relativity Space, and Shiprocket.

Investment focus

Software, FinTech, Financial Services
Seed, Series A, Series B
United States, India, Canada

Portfolio highlights

Sundial — Stop writing pipelines and complex SQL. Go from raw data to entities, metrics, visualizations and answers in just a few clicks
Applied Intuition — Applied Intuition enables engineering and product development teams to safely develop, test, and deploy autonomous vehicles at scale.
Kapital — Kapital empowers SMBs with a tech-banking platform giving visibility and control of their treasury, and their employees

Mechanism Capital is an investment firm that invests in the cryptocurrency industry with a focus on decentralized finance or DeFi.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

DeFi.app — DeFi.app helps to make DeFi trading easier while keeping full ownership of crypto assets. It also helps to manage CEFI and DEFI more effectively.
MagicBlock — MagicBlock Labs is a gaming and technology firm that creates infrastructure for fully on-chain games.
Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Kenetic is a proprietary trading and VC investment firm focused on digital assets and blockchain related companies. They have developed technology to facilitate their quantitative trading strategies and offer various digital asset related structured products to counterparts.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, Hong Kong

Portfolio highlights

CEA Industries — CEA Industries is an agriculture company that offers indoor cultivation services.
VERB Technology Company — VERB Technology Company is a software-as-a-Service, or SaaS, applications platform developer. Its platform is comprised of sales enablement business software products marketed on a subscription basis. The applications are available in both mobile and desktop versions. It includes verbCRM, Customer Relationship Management application, verbLEARN,Learning Management System application, and verbLIVE, its Live Broadcast Video Webinar application.
Fundamental Global — FG Nexus is building a U.S. public company dedicated to Ethereum accumulation and on-chain yield generation, a capital markets vehicle engineered for one of the most important digital assets of this era.

Polygon is the most proven way to build and scale your decentralized application and projects on Ethereum, the world's largest blockchain ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Grant, Series A
United States, Singapore, India

Portfolio highlights

Guild — Guild is a decentralized platform leveraging AI to augment creation, ownership, distribution and monetization of content and digital goods. AI plays a pivotal role in automating tasks, providing data-driven insights, and offering strategic guidance to creators. Whether it's managing marketing campaigns, optimizing release schedules, oridentifying new opportunities, the AI in Guild serves as an invaluable tool for artists, producers, and songwriters. The platform's blockchain integration ensures that all music assets are securely owned and transparently managed, giving creators full control over their work. By combining the practical benefits of AI—like process automation and data analysis—with the security of blockchain, Guild empowers creators to focus on their craft while effectively managing their careers.
Folks Finance — Folks Finance is a DeFi platform to lend, borrow, trade, and manage digital assets all in one place.
Symbiotic — Symbiotic is a generalized shared security system enabling decentralized networks to bootstrap powerful, fully sovereign ecosystems.

Wave Digital Assets offers early-stage investment, asset management, treasury management, and strategy consulting to further the growth of the crypto and digital asset ecosystem.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Funding Round, Series A
United States, Switzerland, Canada

Portfolio highlights

HIFI — HiFi Bridge is a cryptocurrency payments platform that allows customers to buy and sell cryptocurrencies, trade NFT's, borrow loans, and connect their bank accounts all-in-one.The startup offers equity, cryptocurrency, and options trading, as well as cash management accounts. The company provides the accessibility for traditional financialusers to gain access to modern decentralized finance tools through it's mobile and web platform.Zach Walsh and Mohamed Afifi founded the company in New York City in 2021.
Maestro — Advanced UTxO-indexing data layer to supercharge Defi on Bitcoin, Cardano & Dogecoin.
Crypto Valley Exchange — The first portfolio risk capable platform for Options & Futures trading in DeFi, offering 1000x+ leverage based on margin offset.

Wave Digital Assets offers early-stage investment, asset management, treasury management, and strategy consulting to further the growth of the crypto and digital asset ecosystem.

Investment focus

Blockchain, Cryptocurrency, Software
Funding Round, Seed, Series A
United States, Switzerland, Canada

Portfolio highlights

HIFI — HiFi Bridge is a cryptocurrency payments platform that allows customers to buy and sell cryptocurrencies, trade NFT's, borrow loans, and connect their bank accounts all-in-one.The startup offers equity, cryptocurrency, and options trading, as well as cash management accounts. The company provides the accessibility for traditional financialusers to gain access to modern decentralized finance tools through it's mobile and web platform.Zach Walsh and Mohamed Afifi founded the company in New York City in 2021.
Maestro — Advanced UTxO-indexing data layer to supercharge Defi on Bitcoin, Cardano & Dogecoin.
Crypto Valley Exchange — The first portfolio risk capable platform for Options & Futures trading in DeFi, offering 1000x+ leverage based on margin offset.

Alameda Research is a quantitative cryptocurrency trading firm that provides liquidity in cryptocurrency and digital assets markets. It was founded in 2017 and is headquartered in Central and Western, Hong Kong.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Series A, Funding Round
United States, Singapore, Switzerland

Portfolio highlights

3Commas — 3Commas develops a crypto-asset management tool for tracking investments and exchanges in a unified platform. It provides access to a unified dashboard as the central hub for trading and portfolio management execution.
Fuel Labs — At Fuel, we are building the fastest execution layer for the modular blockchain stack.
Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Dapper Labs uses the power of play to deliver blockchain-based experiences that are made for you and ready for the real world.

Investment focus

Blockchain, Software, Cryptocurrency
Seed, Series A, Pre-Seed
United States, Singapore, Canada

Portfolio highlights

Yoz Labs — Save time, streamline your development, and reach users on their preferred channels
Spexi — An intuitive and collaborative platform for drone-based data
Halfbrick Studios — Creators of Fruit Ninja and Jetpack Joyride and more mobile mega hits!

Polygon is the most proven way to build and scale your decentralized application and projects on Ethereum, the world's largest blockchain ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Pre-Seed, Series A
United States, Singapore, India

Portfolio highlights

Guild — Guild is a decentralized platform leveraging AI to augment creation, ownership, distribution and monetization of content and digital goods. AI plays a pivotal role in automating tasks, providing data-driven insights, and offering strategic guidance to creators. Whether it's managing marketing campaigns, optimizing release schedules, oridentifying new opportunities, the AI in Guild serves as an invaluable tool for artists, producers, and songwriters. The platform's blockchain integration ensures that all music assets are securely owned and transparently managed, giving creators full control over their work. By combining the practical benefits of AI—like process automation and data analysis—with the security of blockchain, Guild empowers creators to focus on their craft while effectively managing their careers.
Folks Finance — Folks Finance is a DeFi platform to lend, borrow, trade, and manage digital assets all in one place.
Symbiotic — Symbiotic is a generalized shared security system enabling decentralized networks to bootstrap powerful, fully sovereign ecosystems.

Slow Ventures is a venture capital firm that focuses on investing in companies central to the technology industry as well as those operating at the intersection of science, society, and culture. The firm seeks to support innovative ideas and solutions that shape the future across various sectors.

Investment focus

Software, Internet, Health Care
Seed, Series A, Series B
United States, United Kingdom, Israel

Portfolio highlights

Heave — The Heave App is revolutionizing heavy equipment service. We connect businesses with on-demand diesel mechanics for fast, reliable repairs and maintenance. Our nationwide network of qualified contractors ensures your equipment stays up and running, minimizing downtime and maximizing productivity.
Meroka — Meroka specializes in helping you seamlessly transfer ownership of your medical practice to your employees. Discover expert guidance for a smooth transition today.
Sundial — Stop writing pipelines and complex SQL. Go from raw data to entities, metrics, visualizations and answers in just a few clicks

Lightspeed Venture Partners is a multi-stage venture capital firm focused on accelerating disruptive innovations and trends.

Investment focus

Software, Information Technology, Artificial Intelligence
Series A, Series B, Seed
United States, India, Israel

Portfolio highlights

Tana — Tana is a software development company that reinvents how humans, teams, and computers work together. Tana was founded in 2020 and was headquartered in Oslo, Norway.
Archive — We help brands launch their own secondhand resale marketplace.
Eternal — Eternal provides lifelong athletes with an expert team of health and performance advisors to keep them going in the activities they love for as long as possible.

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