Top 50 Blockchain Startup Investors in United States (July 2026)

Portfolio highlights

• 0xbow — 0xbow is an Ethereum privacy service provider that primarily offers support for Sky’s USDS stablecoin, delivering secure, confidential, and user-friendly transaction solutions within the decentralized finance ecosystem.
• Share — Share XYZ is an information technology service provider
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• Cambrian — Cambrian is an AI infrastructure protocol that creates quickly available financial insight from offchain and onchain data. A decentralized network of validators which catalog blockchain data and quickly extract offchain data powers Cambrian's capabilities.
• Digital Asset — As leaders in blockchain technology, Digital Asset empowers customers with Daml, the leading platform for multi-party applications; an innovative smart contract language and Canton, our privacy-enabled distributed ledger technology.
• M0 —

Portfolio highlights

• Perion — Win Crypto Questing in AAA Games.
• Polkadot — Polkadot is a dedicated community that envisions a web where users own their digital identities and data, restoring their authority.
• Solana Company —

Portfolio highlights

• Zabo — Zabo is an API for connecting to any crypto exchange, wallet, protocol or account. Sign up for access to free API keys at Zabo.com
• Joystream — Joystream is a block chain-based, decentralized video platform.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• RedotPay — RedotPay is a leading crypto fintech bridging Web3 and traditional finance through innovative, cost-efficient blockchain solutions. Our intuitive crypto payment products enable millions of users globally to easily spend and send digital assets. We foster financial inclusion for the unbanked and serve crypto enthusiasts, advancing global adoption offast, accessible crypto payments.
• EigenLabs — Eigen Labs is an engineering and research organization that contributes to protocols like EigenLayer and EigenDA
• Fabric Cryptography — Fabric develops a custom cryptography hardware to accelerate cryptography algorithms. The chips, whose components exclusively serve cryptographic purposes, are based on Verifiable Processing Units (VPUs) which incorporate features of GPUs and ASICs to improve the speed and cost of advanced cryptographic workloads.

Portfolio highlights

• GTE — GTE is a decentralized trading platform that offers end-to-end trading services.
• Hylo —
• Sprinter —

Portfolio highlights

• Enso Finance — Social trading redefined. Create Alpha strategies, share and compete with your friends, community or DAO. Discover and create open defi strategies page.
• Inference — Inference is a distributed GPU cluster for LLM inference based on Solana, providing a fast, scalable, and token-based API for models such as DeepSeek V3 and Llama 3.3.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• EDGE Markets — The Financial Platform for Smart Bettors
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• Tools For Humanity — Tools for Humanity is a technology company building for humans in the age of AI.

Portfolio highlights

• Rocket — Rocket is an on-chain prediction market platform enabling real-time price forecasts with continuous, accuracy-based rewards.
• Squads — Collaborative infrastructure for web3 native teams
• Legend. trade — Legend. trade is a crypto trading company by decentralized exchange.

Portfolio highlights

• Tazapay — Experience Tazapay's best-in-class global payment solutions for businesses. Our extensive network supports cards, local payment options, and bank transfers in over 173 countries, ensuring seamless collections, secure holding, and efficient payouts worldwide.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• The Giving Block — The Giving Block makes it easy for nonprofits to accept non-cash donations like crypto and stocks for 2,000+ nonprofits. The Giving Block is the largest platform that helps nonprofits accept crypto and stock donations. In 2022, it was acquired by Shift4, a publicly traded payments company.

Portfolio highlights

• GameFi.org —
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• AI Pay with Crypto — AI Pay with Crypto is an AI-native financial infrastructure built for the emerging agent economy.APC enables autonomous AI agents to execute payments, settle transactions using programmable stablecoins, and connect directly to real-world merchant networks through QR codes, POS terminals, and other payment channels

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Faith Tribe — Faith Tribe is a open- source fashion design platform that focuses on NFT minting, P2P transactions.

Portfolio highlights

• BizScout — BizScout is an online platform of Off market deals for verified buyers and sellers.
• Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.
• M1X Global — M1X unlocks new applications of blockchain technology across public sector programs and institutional markets. We partner with governments to identify opportunities, coordinate expertise and support long-term economic development.

Portfolio highlights

• Gondi — Gondi is a non-custodial decentralized NFT lending protocol designed to build the most effective NFT credit market. The protocol allows for ongoing underwriting and full and partial refinancing of all outstanding loans, resulting in a more dynamic and liquid market.
• Mudafy — Mudafy is a tech-enabled real estate broker for LatAm.
• Hyperlane — Hyperlane is the platform for developers building the interchain universe

Portfolio highlights

• Zora — Zora operates as a crypto-driven marketplace.
• Global Token Exchange — Global Token Exchange is an end-to-end decentralized trading platform with CEX-level performance.
• The Wildcard Alliance — A new platform is coming where YOU are the Wildcard. Sign up and follow for the latest announcements.

Portfolio highlights

• Fence — At Fence, we're transforming the way debt facilities are managed. We are the Operating System for your debt facility, reducing the amount of resources spent in back-office operations and letting teams focus on what matters.Our platform, built on blockchain technology, offers a Software as a Service (SaaS) solution that simplifies andautomate debt facility operations. Whether you're a capital provider or an asset originator, Fence leads you toward a smarter financial future.For capital providers, our platform enables internet-native debt solutions and real-time portfolio insights, enhancing your credit investment monitoring. With Fence, you stay ahead, making informed decisions for success. Asset originators benefit from enhanced capital efficiency and reduced operational costs, thanks to Fence's automation. We seamlessly integrate debt facilities into your tech stack and provide on-demand programmable debt, giving you unprecedented control over the capital you borrow.
• TBD —
• Blockworks — Blockworks is a financial media brand that delivers breaking news and premium insights about digital assets to millions of investors. Our editorial content, newsletters, podcasts and events provide investors with the critical analysis and information they need to make smarter decisions about digital assets.

Portfolio highlights

• Portal to Bitcoin — The only custody-less interoperability protocol for Bitcoin. Swap native BTC, Ordinals, Runes with L2s and L1s
• ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
• Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem

Portfolio highlights

• Axis — Axis provides infrastructure for global price synchronization and yield generation.
• Zoo Finance — Zoo Finance is a pioneering DeFi protocol focused on unlocking liquidity from locked assets, empowering users to access capital more efficiently while maximizing the utility of their on-chain holdings.
• Hypernova — Hypernova is an on-chain proprietary (prop) trading platform built on the Hyperliquid Layer-1 blockchain, designed to bring the traditional prop trading model fully on-chain with transparent, automated rules.

Portfolio highlights

• AlchemyNFT — AlchemyNFT is a non-fungible token (NFT) service.
• Perion — Win Crypto Questing in AAA Games.
• Mighty Bear Games — Mighty Bear is a Singapore-based studio building the next generation of massively multiplayer online mobile games. The team is a collective of games industry vetarans from the likes of King, Ubisoft, EA, Lucasarts, Disney, Gameloft, and Jagex. Mighty Bear make games that combine the depth of desktop gaming with the accessibility of mobile -"Mobile games without compromise".

Portfolio highlights

• SIBEX — Trade securely and directly between BTC and any ERC20 - Atomic cross-chain swaps. No Account Creation. No middlemen. Global Liquidity.
• OceanEx — OceanEx is one of the fastest-growing and reputable cryptocurrency exchange.
• BlockSeer — Raw data; real insight. Built for Bitcoin mining teams that want answers, not overhead. Free Bitcoin transaction explorer and wallet monitoring tool.

Portfolio highlights

• Cazena — Cloudera delivers a hybrid data platform with secure data management and portable cloud-native data analytics.
• Shapeways — Shapeways is the #1 online 3D printing service company. Working with over a million customers since 2007 - Get 3D products and parts delivered to over 100 countries.
• Co:Create — The Co:Create protocol provides the foundational infrastructure for decentralized brands of the future. It enables projects to mint NFTs, as well as launch their own DAOs and fungible tokens associated with their collections.

Portfolio highlights

• NextDroid — NextDroid - We're Doing Something Different
• Enact — Enact is a leading solar energy and solar software company serving homeowners, businesses, and installers. Get a free quote or request a demo today!
• ARRIS — Using next-gen advanced manufacturing technologies, ARRIS Composites produces smarter, lighter, stronger, and more sustainable products at scale.

Portfolio highlights

• CryptoMove — Buy a perfect domain name from Sudos.com. Discover thousands of domain names available for sale. Sudos.com keeps you safe.
• Peer Robotics — Discover the latest cutting-edge robotics solutions at Peer Robotics. We offer innovative products and services to revolutionize industries.
• Picnic — The Picnic Pizza System is a modular, easy-to-use, automated pizza assembly system that saves time, money, and labor without compromising quality.

Portfolio highlights

• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• Perion — Win Crypto Questing in AAA Games.
• Saturn — Saturn is the first financial application built on digital credit.

Portfolio highlights

• Collector —
• Watch.fun —
• Solana Company —

Portfolio highlights

• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• Flying Tulip — Better Yield, Better UX
• Hypernova — Hypernova is an on-chain proprietary (prop) trading platform built on the Hyperliquid Layer-1 blockchain, designed to bring the traditional prop trading model fully on-chain with transparent, automated rules.

Portfolio highlights

• The Trive — The Trive is a car subscription service platform through which users can pay a monthly subscription fee to drive the car they most desire.
• DarcMatter — DarcMatter is a fintech platform that provides cloud based infrastructure for asset managers to better manage, communicate and access investors. By utilizing proprietary structuring and technology, DarcMatter is able to provide a frictionless process for both investors and private issuers while remaining fully compliant of all current financialregulations.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• Megapot —
• Rhythmic —
• Teleport — Meet your most compatible connections. Attend members only curated experiences. Receive proposed matches from your AI Matchmaker.

Portfolio highlights

• MyVR — Guesty is a property management platform. It is used by property managers to manage Short-Term Rentals and Vacation Rentals listed on multiple platforms such as Airbnb, HomeAway, and Booking.com
• Espa — Espa provides an AI assistant platform that helps individuals and organizations manage email, scheduling, and personal or work tasks. The service connects to users’ inboxes and calendars to flag priority messages, draft context-aware responses, and coordinate meeting times. Users can interact with Espa via messaging channels such as text, WhatsApp,and other chat tools to book appointments, set reminders, and follow up on tasks. The platform offers plans for personal use, professional assistants, and larger enterprises, with options for multiple inboxes, synced calendars, and integrations with tools like email, calendar, storage, and collaboration systems. Espa emphasizes privacy controls, encryption, and user management features for larger teams.
• NavigateAI — NavigateAI is an AI copilot for the physical world specifically designed for construction and field service teams to help them complete projects faster, with higher quality, and at lower costs.

Portfolio highlights

• BetHog — BetHog is a new crypto sports book that brings home the bacon.
• Kairos Labs — Kairos Labs is an Ethereum ecosystem interest rate swap protocol
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• Brale — Combining the best of CeFi & DeFi.
• Razorpay — Online Payments India: Start Accepting Payments Instantly with Razorpay's Payment Suite, which Supports Netbanking, Credit Card & Debit Cards, UPI etc.
• Matillion — Enterprise level data integration tools built for the cloud. Harness your data into transformative business insights. Your data is your competitive edge.

Portfolio highlights

• Adim — Adim is a community of storytellers, fans and friends working together to create and own an entire narrative universe.
• Yupp — Every AI for everyone
• Talos — Talos powers institutional access to the digital assets market - With full trade lifecycle coverage from price discovery through to execution and settlement.

Portfolio highlights

• Coverio — Coverio is a software company that offers enterprise-wide payroll and hiring management software for web4 companies.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!

Portfolio highlights

• IOTrader — IOTrader is a financial technology company operating a high-volume perpetual decentralized exchange (DEX). Specializing in decentralized finance (DeFi), the platform provides secure, audited cryptocurrency trading for tens of thousands of active monthly users.
• Tomoland — Tomoland is a social gaming platform where users create avatars, worlds, and multiplayer experiences.
• Midas — Structured Products, Onchain.

Portfolio highlights

• Hylo —
• Slope Finance — Slope is a community-based decentralized exchange built on Solana.
• Yield Guild Games Southeast Asia — YGG SEA is a sub-decentralized autonomous organization (subDAO) of the play-to-earn blockchain game YGG. The YGG SEA will be based on smart contracts built on the Etherum blockchain.

Portfolio highlights

• Trufin — TruFin offers software and niche lending solutions, specializing in liquid staking and Web3 financial tools.
• LIFE AI — LIFE AI (lifenetwork.ai) is an AI-powered blockchain platform for decentralized science in genomics, enabling users to own, control, and monetize personal genomic data while accelerating personalized medicine development 10x faster and cheaper.​ It provides clean, labeled genetic profiles via the LIFE Chain, LIFE App, and marketplace, supportingfeatures like DNA-powered LIFE IDs and Gene NFTs for secure, transparent data access.
• Security Token Partners (now Security Token Group) —

Portfolio highlights

• AlphaPoint — Join over 150 customers from 35 countries that have leveraged AlphaPoint's white label software to launch and operate digital asset markets.
• Argo Blockchain — Argo Blockchain (NASD:ARBK), is the First Climate Positive Bitcoin Mining Company. A Pioneer in Using Renewable Power & Innovation in Blockchain Technology
• Digital Prime Technologies — Full-Service Institutional-Grade Prime Brokerage for Digital Asset Management. DLCC offers full-service Prime Brokerage solutions for digital assets. Our all-in-one user interface leverages both API and Saas product offerings to connect clients with a growing network of liquidity providers to transact, borrow, and lend digital assets, and managecollateral. Our product suite also offers traditional Prime Brokerage services, such as consultation and capital introduction.

Portfolio highlights

• AltLayer — AltLayer is a system of highly scalable application-dedicated execution layers that derive security from an underlying L1/L2.
• Panoptic — The Panoptic protocol enables the minting, trading, and market-making of perpetual put and call options.
• Mask Network — Your Portal To The New, Open Internet.

Portfolio highlights

• XMTP — XMTP is a decentralized and quantum-resistant messaging protocol for builders.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• Superstate — Superstate is modernizing investing through tokenized financial products

Portfolio highlights

• MoonPay — MoonPay offers a fast and simple way to buy and sell cryptocurrencies. Buy crypto with credit card, bank transfers or Apple Pay today.
• Disclosure Facts — Prevent FTC disclosure risk and ad disputes with a provable system of record for creator and influencer ad disclosures.
• Diadia Health, Inc — An AI medical reasoning platform that helps clinicians analyze the root causes of symptoms and create personalized protocols that drive better outcomes.

Portfolio highlights

• Wizzwoods — Wizzwoods is an open-world farming strategy game.
• Metatheory — Metatheory Inc. is an interactive technology and entertainment company building Web3 games, interactive content, social experiences, and other community-driven adventures. Metatheory’s mission is to inspire imagination by connecting people worldwide through immersive worlds built on cross-generational IP.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• Zabo — Zabo is an API for connecting to any crypto exchange, wallet, protocol or account. Sign up for access to free API keys at Zabo.com
• Mash — The internet is fundamentally broken. It's because of monetization. “Show me the incentives and I'll show you the outcome.”Our mission is to remonetize the web by enabling value for value monetary exchanges between pubs/creators/orgs and their users. A new business model for the open internet.We are unlocking this withfriction-minimized streaming payments that are no/low cost, instantly settled, trust-minimized.It is built on the best global digital monetary network ever conceived, Bitcoin. Enabled by Lightning Network. Most users don't need to know this or be a Bitcoiner. Over time we suspect many will.
• XFX — XFX makes global money movement fast, transparent, and capital-efficient across fiat and stablecoin rails.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• SuperIntent —
• Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Portfolio highlights

• AKEDO — AKEDO is a AI framework that creates and designs engaging games.
• Diadia Health, Inc — An AI medical reasoning platform that helps clinicians analyze the root causes of symptoms and create personalized protocols that drive better outcomes.
• Tools For Humanity — Tools for Humanity is a technology company building for humans in the age of AI.

Portfolio highlights

• Perion — Win Crypto Questing in AAA Games.
• Farmington State Bank — Do more with a Moonstone FDIC insured bank account and manage your non-traditional assets from the same place.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• Joystream — Joystream is a block chain-based, decentralized video platform.
• Superstate — Superstate is modernizing investing through tokenized financial products
• Tools For Humanity — Tools for Humanity is a technology company building for humans in the age of AI.

Portfolio highlights

• Project Eleven — Project Eleven is a development company dedicated to advancing post-quantum cryptography solutions.
• Tenbin Labs — Tenbin Labs is a New York-based startup developing a tokenized asset protocol for real-world assets like commodities and foreign exchange markets.
• Birch Hill Holdings — Birch Hill Holdings provides digital asset infrastructure for institutions allocating capital onchain. The firm focuses on onchain lending, tokenized asset markets, and digital asset treasury workflows. It offers risk curation, yield vault management, and portfolio visibility tools that emphasize disciplined credit underwriting, constraints, andcontinuous monitoring. Its services aim to bridge traditional and decentralized finance for institutional participants managing digital asset exposure.

Portfolio highlights

• Guild — Guild is a decentralized platform leveraging AI to augment creation, ownership, distribution and monetization of content and digital goods. AI plays a pivotal role in automating tasks, providing data-driven insights, and offering strategic guidance to creators. Whether it's managing marketing campaigns, optimizing release schedules, oridentifying new opportunities, the AI in Guild serves as an invaluable tool for artists, producers, and songwriters. The platform's blockchain integration ensures that all music assets are securely owned and transparently managed, giving creators full control over their work. By combining the practical benefits of AI—like process automation and data analysis—with the security of blockchain, Guild empowers creators to focus on their craft while effectively managing their careers.
• Open Campus — The Open Campus is a community-driven protocol that leverages the power of blockchain and invites all to build the future of education by putting the power of learning back in the hands of educators, students, and the community.
• Pheasant Network — Pheasant Network uses intent-based bridging and an innovative cross-chain swap protocol to connect 30+ blockchain networks quickly and efficiently.

Portfolio highlights

• Flood — Flood: The best DEX aggregator to optimize your trading. Experience top rates, zero gas fees, and full MEV protection. Trade across Arbitrum and Ethereum today.
• Stack — Recognize and reward the relationships that matter
• Reservoir — Infrastructure and APIs to bring efficient token markets to every chain, wallet, and app