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Top 50 Health Care Startup Investors in United States in January 2025

Last updated: Jan 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Health care startups based in United states. We rank investors based on the number of investments they made in Health care companies from United states. We update this investor list every month.

Top 50 Health Care Startup Investors in United States in January 2025

Investor	Health Care United States investments
Innova Memphis	133
SOSV	123
ARCH Venture Partners	112
Alumni Ventures	107
New Enterprise Associates	106
Khosla Ventures	98
Right Side Capital Management	91
Rock Health Capital	88
F-Prime Capital	87
StartUp Health	84
OrbiMed	83
Polaris Partners	83
Alexandria Venture Investments	80
Gaingels	79
Andreessen Horowitz	78
Connecticut Innovations	78
General Catalyst	78
Versant Ventures	74
Lux Capital	73
Atlas Venture	73
Canaan Partners	70
First Round Capital	69
Portfolia	66
Third Rock Ventures	64
BioAdvance	64
5AM Ventures	64
Founders Fund	63
MPM Capital	62
SV Angel	62
BoxGroup	60
Google Ventures	59
HealthTech Capital	56
Wavemaker 360	55
Rev1 Ventures	55
RA Capital Management	52
Kleiner Perkins	50
TEDCO	50
8VC	49
Great Oaks Venture Capital	49
KdT Ventures	49
DCVC	48
Felicis	48
True Ventures	48
Asset Management Ventures (AMV)	47
MB Venture Partners	47
Ben Franklin Technology Partners of Southeastern Pennsylvania	47
Greycroft	47
Hatteras Venture Partners	47
Fifty Years	45
Slow Ventures	45

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Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, China, United Kingdom

Portfolio highlights

Rhygaze — Rhygaze develops a novel gene therapy that targets cone cells to restore vision in patients suffering from diseases causing blindness.
nChroma Bio — nChroma Bio's integrated product engine allows for safe, accurate, and targeted in vivo administration, addressing major shortcomings of current genetic medicine techniques.
Tenvie Therapeutics — Tenvie Therapeutics is a biotechnology company founded to improve patients' lives with neurological, cardiometabolic, and ophthalmic diseases. The company is focused on developing small molecules targeting brain inflammation, metabolic dysfunction, and lysosomal issues, with a robust pipeline inherited from Denali Therapeutics. Tenvie isprogressing a range of therapeutics aimed at addressing neurological, cardiometabolic, and ophthalmic conditions. Its collection of fully owned, highly brain-penetrant, and precisely designed peripherally restricted small molecules targets three main factors of disease: alleviating inflammation, correcting metabolic dysfunction, and rejuvenating lysosomal function.

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Spintly — Integrate the Spintly Smart Access control system with your apps and software, without having to toggle between multiple devices & software.
Torch Dental — Torch Dental develops an all-in-one technology designed to meet dental practices' supply ordering and inventory management needs. Torch Dental simplifies and streamlines the ordering process, allowing dentists to focus on their patients.
Mojave Energy Systems — Mojave the latest in HVAC innovation. Help the Climate. Reduce Energy Use. Improve Indoor Comfort. Perform Reliably. Lower Costs.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, China

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
Ouro Medicines — Ouroboros Medicines is a biotechnology company that specializes in immunology and focuses on treating long-term immune-mediated illnesses. The company addresses chronic immune-mediated conditions directly by integrating scientific knowledge, a proven history of progressing cell-depleting treatments through clinical trials, and a strong pipeline.
Orbis Medicines — Orbis Medicines is a novel macrocyclic chemistry and computational platform for high-throughput drug discovery.

Khosla Ventures invests in companies that are bold, early, and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs.Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech, digital health, medtech anddiagnostics, therapeutics, and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Zetwerk — Zetwerk offers high-quality production, globally competitive costs, and unparalleled lead times in every area of manufacturing.
Jones — Jones is a software company that rebuilt liability management for real estate companies who want do less and get more – much more. We are solving one of the most archaic and outdated processes in commercial real estate - insurance certificates. For owners, managers and developers who need to solve insurance compliance for everyone in the valuechain, Jones is the simplest solution ever made.
Basis — Basis operates as an AI platform built specifically for accounting firms.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
UBILD — A.I powered construction workforce and vendor procurement platform
Hutsy — Hutsy helps you budget, spend less and offers a concierge service to handle tasks like negotiating bills, canceling subscriptions, saving you time and money.

We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.

Investment focus

Health Care, Software, Medical
Seed, Series A, Series B
United States, Denmark

Portfolio highlights

Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Synapticure — The era of personalized care is finally coming to ALS. Synapticure will give all ALS patients access to the best care while fueling the advancement of personalized treatments for every type of ALS.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

Rhygaze — Rhygaze develops a novel gene therapy that targets cone cells to restore vision in patients suffering from diseases causing blindness.
TripSuite — Spend more time growing your agency and less time tracking commissions.
Tenvie Therapeutics — Tenvie Therapeutics is a biotechnology company founded to improve patients' lives with neurological, cardiometabolic, and ophthalmic diseases. The company is focused on developing small molecules targeting brain inflammation, metabolic dysfunction, and lysosomal issues, with a robust pipeline inherited from Denali Therapeutics. Tenvie isprogressing a range of therapeutics aimed at addressing neurological, cardiometabolic, and ophthalmic conditions. Its collection of fully owned, highly brain-penetrant, and precisely designed peripherally restricted small molecules targets three main factors of disease: alleviating inflammation, correcting metabolic dysfunction, and rejuvenating lysosomal function.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

Rapt Therapeutics — RAPT Therapeutics is a clinical stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in oncology and inflammatory diseases. Utilizing its proprietary discovery and development engine, the company is developing highly selectivesmall molecules designed to modulate the critical immune responses underlying these diseases. In its first four years since inception, RAPT has discovered and advanced two unique drug candidates, each targeting C-C motif chemokine receptor 4. The company’s lead oncology drug candidate, FLX475, reached the clinic in just two and a half years with its lead inflammation drug candidate, RPT193, also in the clinic. The company is also pursuing a range of targets, including general control nonderepressible 2 and hematopoietic progenitor kinase 1, that are in the discovery stage of development.
Verdiva Bio — Verdiva Bio is committed to developing next-generation therapies to help people living with obesity, cardiometabolic disorders, and related complications achieve better outcomes via more patient-friendly therapeutic options.
Aviceda Therapeutics — Aviceda Therapeutics is a late-stage, pre-clinical biotech company developing drugs for treating glyco-immune diseases. The company focuses on the next generation of immunomodulators by harnessing the power of glycobiology to address the innate immune system and chronic non-resolving inflammation specifically and profoundly. A combination ofcutting-edge technologies and deep biological insights form Aviceda’s engine of transformative product creation.Aviceda uses its cell-based high-throughput screening (HTS) platform to rapidly screen, select, and optimize ligands based on maximum affinity and specificity for each different type of innate immune cell. . The company's products are for eye diseases, fibrosis, neurology, and oncology, for eye diseases like AVD-104, AVD-302, AVD-401 for dry eye, diabetic retinopathy, and retinoblastoma respectively AVD-601, AVD-701 and AVD-801 for oncology, neurology, and fibrosis respectively.

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Ireland, Singapore

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
TRex Bio — TRexBio is a discovery stage biotechnology company leveraging cutting-edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for cancer and inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us toidentify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.
Noema Pharma — BEYOND SYMPTOM CONTROL Developing therapies to help both orphan and larger patient populations with conditions of the brain and nervous system live their li ...

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Seed
United States, Canada, France

Portfolio highlights

nChroma Bio — nChroma Bio's integrated product engine allows for safe, accurate, and targeted in vivo administration, addressing major shortcomings of current genetic medicine techniques.
Nuvig Therapeutics — Nuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune homeostasis, rebalance immune function following inﬂammation, and improve the treatment options for patients. Nuvig is building a pipeline of novel immune therapeutics for chronic inflammatory and autoimmunediseases.
Autoimmunity BioSolutions — ABS is developing a next-generation, immuno-corrective therapy to restore normal immune function in a genetically-defined subpopulation of autoimmune disease patients.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

OneRail — OneRail is a final mile delivery orchestration platform providing real-time visibility, actionable data, and data-driven optimization capabilities for its enterprise clients. OneRail’s cloud-based “delivery switch” simplifies same-day and on-demand delivery execution by connecting the demand signal (POS, eCommerce, ERP) with the ecosystem ofdelivery networks and internal fleets in real-time. The result of OneRail’s centralized view of disparate final mile data enables data-driven optimization, positively impacting the dependability, speed, and cost of final mile fulfillment.
Holly — Holly operates as an AI company that modernizing government hiring.
Qnovia — Respira Technologies is a platform device and biotechnology company focusing on aerosol science. The company is creating breakthrough aerosol devices and formulations that safely deliver a broad range of pharmaceuticals and nicotine.Respira Technologies' mission is to create novel medical devices of unparalleled efficiency and to advance theprotection of public health with consumer devices through novel innovation, responsible sourcing, draft legislative proposals, transparent product information, and common sense oversight.

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Brazil

Portfolio highlights

Whatnot — Whatnot is a community marketplace where you can safely buy, sell, go live and geek out with collectors and other like-minded people. All items on Whatnot are verified. Shop on web or download the app.
Anysphere — Anysphere is a company that builds Artificial Intelligence tools and assistants to help humans.
Hippocratic AI — The First Safety Focused LLM for Healthcare

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

CREW Carbon — CREW Carbon is on a mission to remove CO2 across Earth's water cycle by first leveraging wastewater systems as a scalable, deployable solution today. We empower the global wastewater sector to lead the fight against climate change.
VeraDermics — VeraDermics Inc. is a dermatology pharmaceutical start-up, makers of WartPatch
Nimbus Power Systems — Nimbus builds a cleaner world through design and integration of zero-emission fuel cell systems for heavy-duty markets.

Investing in powerful, positive change that endures

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Seed, Series B
United States, India, United Kingdom

Portfolio highlights

Cartesia — Cartesia provides real-time multimodal intelligence for all devices. Its objective is to develop the next generation of AI: pervasive, interactive intelligence that operates everywhere.
Current — Current is a financial technology company that offers mobile payments, online banking, and financial services. The company's mission is to enable members to change their lives by creating better financial outcomes. It was founded in 2015 and headquartered in New York, United States.
Hippocratic AI — The First Safety Focused LLM for Healthcare

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

858 Therapeutics — 858 Therapeutics is a stealth company specializing in the area of healthcare services, pharmaceutical, and biotechnology. The company was founded in 2019 and is headquartered in San Diego, California, USA.
Antag Therapeutics — Antag Therapeutics operator of a biotechnology company intended to develop metabolic and anti-obesity therapeutic drugs.The company specializes in the development of peptide-based GIP receptor antagonist in order to monitor dietary-related metabolic diseases through the infusion, enabling the healthcare industry to decrease blood flow and lipiduptake in adipose tissue in an efficient manner.
Pep2Tango Therapeutics — Pep2Tango Therapeutics is a biotechnology company that offers superior unimolecular multi-receptor drugs for obesity and related disorders.

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Biotechnology
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Cala Health — Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company's wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation. The first indication for Cala Health's wearable therapy is an essential tremor, adisease experienced by more than seven million people and characterized by severe hand tremors. New therapies are under development in neurology, cardiology, and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.
Fiddler AI — Monitor, observe, analyze, and explain your machine learning models in production with Fiddler AI. Maximize ML model performance with our Model Performance Management Platform that simply plugs in.
Bluenote Health — Accelerate innovation with AI built for and trusted by leading life sciences companies.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, United Kingdom, Israel

Portfolio highlights

Glooko — Glooko's digital health and connected care solutions improve health outcomes for people with diabetes and related chronic conditions.
Nivoda — Nivoda provides jewellery businesses with a simple solution to strengthen profits, increase efficiency and accelerate growth with its B2B diamond marketplace. Designed to save you time and money whilst giving you access to the world’s diamond supply at the best prices with zero inventory risk, Nivoda is trusted by thousands of retailers all overthe globe.
Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

Investment focus

Software, Information Technology, Internet
Seed, Series A, Series B
United States, Canada, India

Portfolio highlights

Reducto — Reducto is an API that provides high quality data ingestion for large language models (LLMs). It works with any vector database or embedding system. It can parse PDFs, Excel, PowerPoint, and more.
Omnea — The all-in-one procurement platform. Request purchases, automate approvals, and streamline your procurement process in one centralised solution.
Prepared — We are harnessing the power of everyday technology to enhance the way that people communicate during emergencies.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Software, Biotechnology
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and
Zero Point Five Therapeutics — A drug development company treating soil transmitted helminthiasis (STH) through the FDA as a single dose formulation. STH is a disease impacting poor rural communities of color with poor sewage systems.

Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Marea Therapeutics — Marea Therapeutics is a clinical-stage biotechnology firm that uses the most recent advancements in human genetics to create first-in-class, next-generation medications for cardiometabolic illnesses.
Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.
Candid Therapeutics — Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions.

BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.

Investment focus

Biotechnology, Health Care, Medical
Seed, Funding Round, Series A
United States, Canada

Portfolio highlights

KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies. they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Switzerland, United Kingdom

Portfolio highlights

RareCyte — Rarecyte provides precision medicine solutions focused on multiplexed analysis of cells and tissue with applications in both research and clinical diagnostics.
TMRW Life Sciences — TMRW helps patients and clinics safely store their eggs and embryos
Tectonic Therapeutic — Tectonic and AVROBIO have completed their anticipated merger.Please follow this link to our press release for additional information.

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Network Bio — Network Bio is a clinical and molecular data library enabling precision medicine approaches for common human diseases. Its platform delivers a centralized repository for clinical and molecular data that allows researchers to identify patterns and correlations that can be used to develop new treatments and diagnostic tools.
Crusoe Energy Systems — Crusoe is on a mission to help the oil industry reduce routine flaring of natural gas. They are passionate about creating solutions that benefit the environment, local communities, and energy producers.Crusoe Energy Systems provides oil and gas companies with a fast, low cost and simple solution to natural gas flaring. As the energy industrystruggles with pipeline constraints and increasing regulations around flaring and combusting, Crusoe is here to help. Their service lets operators preserve or regain regulatory compliance, maintain existing production and facilitate future development.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series B, Series A, Series C
United States, United Kingdom, Canada

Portfolio highlights

AstronauTx — AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.
Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies

SV Angel is a San Francisco-based venture fund. Their experience spans helping companies like Airbnb, Coinbase, Databricks, DoorDash, Faire, Flexport, GitHub, Notion, Pinterest, Snap, Square, and Stripe Scale. Over the last 30 years of investing, their core values of trust, loyalty, and integrity along with a founder-first approach have driven ourstrategy. They are a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

Investment focus

Software, Internet, Mobile
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Cartesia — Cartesia provides real-time multimodal intelligence for all devices. Its objective is to develop the next generation of AI: pervasive, interactive intelligence that operates everywhere.
Hippocratic AI — The First Safety Focused LLM for Healthcare
Plume Network — Plume is the first modular L2 blockchain for RWAs that simplifies onchain asset deployment while fostering a composable ecosystem through DeFi applications

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

Investment focus

Software, Health Care, Internet
Seed, Series A, Series B
United States, France, Mexico

Portfolio highlights

Gigs — Gigs is building Stripe for SIM cards. Providing platforms custom phone & data plans through an easy to use API in 180+ countries.
Prima — Reliable manufacturing & supply chain partner for custom parts, metal fabrication & efficient sourcing from Mexico. Manage design, production & delivery
Tempest — Tempest is a ready-to-use self-serve platform that enables developers to automate app development, deployment, and management while ensuring security and compliance.

GV supports innovative founders moving the world forward.

Investment focus

Software, Health Care, Biotechnology
Series A, Series B, Seed
United States, United Kingdom, Switzerland

Portfolio highlights

Rhygaze — Rhygaze develops a novel gene therapy that targets cone cells to restore vision in patients suffering from diseases causing blindness.
Cala Health — Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company's wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation. The first indication for Cala Health's wearable therapy is an essential tremor, adisease experienced by more than seven million people and characterized by severe hand tremors. New therapies are under development in neurology, cardiology, and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.
Prudentia Sciences — Prudentia Sciences is a platform enables AI-powered Asset Diligence and Valuation to De-Risk Investment in Drug Development.

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

Investment focus

Health Care, Medical Device, Medical
Seed, Series A, Convertible Note
United States, Canada

Portfolio highlights

xCures — An AI-assisted platform that can automatically retrieve medical records from anywhere in the US, within 15 minutes, and extract vital data
S2 Genomics — The Singulator Platform automates the dissociation of tissues into single cells and nuclei for genomics applications. Learn more at S2genomics.com
GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

Feeling Great — Feeling Great is a mental wellness app that offers a revolutionary AI-powered chatbot and interactive learning program, which have been developed based on the groundbreaking work of David Burns, MD and his T.E.A.M. approach to cognitive behavioral therapy.
Marigold Health — Marigold Health is an anonymous social network where people with mental health and substance use conditions support each other.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
United States, Germany

Portfolio highlights

HubiFi — SaaS Financial Automation & Analysis for High Transaction Businesses
Myoptechs — Myoptechs, a pediatric ophthalmic medical device startup in the clinical stage, has made advancements in its fund-raising and clinical research program. The company creates innovative soft contact lenses and spectacles that reduce the growth of myopia while offering incredibly clear vision.
Power to Hydrogen — Power to Hydrogen (P2H2) is simplifying hydrogen. Our technology enables a brighter energy future by solving the technical and economic challenges that come with producing hydrogen. Our AEM-based, electrolysis technology produces high pressure, high efficiency hydrogen from renewable energy with lower cost materials thancompeting electrolyzers. This technology can reduce the total cost of hydrogen to enable clean transportation, store energy efficiently, and decarbonize industrial processes. In addition to low-cost, high-pressure hydrogen production, the technology can produce high-pressure oxygen and be used reversibly to produce electricity. Both services can create additional revenue streams to make the total cost of hydrogen $1/kg.

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

Investment focus

Biotechnology, Health Care, Therapeutics
Series B, Series C, Series A
United States, United Kingdom, Canada

Portfolio highlights

Monopar — Monopar Therapeutics is an emerging biopharmaceutical company focused on developing orphan oncology compounds.Its lead compound, Hu-ATN-658, is a novel monoclonal antibody for the potential treatment of several deadly cancers. Hu-ATN-658 targets the urokinase plasminogen activator receptor (uPAR). Cancer Research UK will be conductingHu-ATN-658’s early development, including a Phase I clinical trial.In 2014, Chandler D. Robinson, Christopher M. Starr, and Andrew P. Mazar founded the company in Wilmette, Illinois.
Verdiva Bio — Verdiva Bio is committed to developing next-generation therapies to help people living with obesity, cardiometabolic disorders, and related complications achieve better outcomes via more patient-friendly therapeutic options.
Vor Biopharma — Shield the healthy cells, expose the cancer - Vor Bio (also known as Vor Biopharma) aims to cure blood cancers through cell and genome engineering.

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

Terradot — The Earth Regeneration Company
Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.
Hippocratic AI — The First Safety Focused LLM for Healthcare

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

Investment focus

Health Care, Software, Biotechnology
Seed, Grant, Pre-Seed
United States, Canada

Portfolio highlights

Escalate USA — At Escalate, we solve the talent crisis for retail corporations. We increase employee retention and the internal pool of skilled middle-wage candidates by providing frontline workers with weekly asynchronous online training that leads to industry-recognized certifications and upward mobility.
Pedestal — Pedestal creates visual albums for artists.
Tight & Right Hair Revolution — WELCOME Tight & Right Hair Revolution Inc Where we specialize in beautifying fitness! We are a company that focuses on creating innovative hair technology to help improve the ease of maintaining your style! OUR STORY This one hits home for me personally. My mom has...

8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Surglogs — Surglogs streamlines and automates the administration of logbooks, medications, supplies, in-services, and drills in healthcare facilities. The outdated pen-and-paper method is replaced with a HIPAA compliant state of the art digital application, complemented with a desktop portal that serves as an administrative dashboard.Surglogs was founded in2015 and headquartered in California, United States.
Seen Health — We are building a culturally-focused, technology-enabled healthcare organization that integrates comprehensive medical care and social support with a high-touch, interdisciplinary approach. We plan to augment a proven home and community based services model by embracing the unique cultural and healthcare needs of the communities we serve, and empowering our staff with thoughtfully designed technology to scale the highest quality care to many more older adults.
Reveal Technology — Reveal Technology is the next-generation defense technology platform, delivering a suite of products that generates critical intelligence and autonomy value at the tactical edge.

Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.

Investment focus

E-Commerce, Software, Health Care
Seed, Series A, Series B
United States, United Kingdom, Spain

Portfolio highlights

Fleet — Fleet is a mobility-as-a-Service software for enterprise transportation needs.
Amulet — Amulet is shining a light on invisible threats in our food system. Amulet has two core brands: - Allergy Amulet helps consumers determine whether their foods are safe by detecting potentially life-threatening allergenic ingredients. - Amulet Scientific equips businesses and manufacturers with tools to help ensure the safety of their food supplychain. Learn more: www.allergyamulet.com www.amuletscientific.com
Tracer Biotechnologies — Tracer Biotechnologies is a biotechnology company that offers monitoring services for oncology patients.

KdT Ventures is the standard for early-stage frontier science investing.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Israel, Germany

Portfolio highlights

Shiprocket — Shiprocket is India's most-used eCommerce logistics and shipping software solution for the best courier services. Avail features like COD (Cash on Delivery), prepaid delivery, automated shipping, etc.
March Biosciences — Transforming Patient Care by Unlocking New Target Spaces March Biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity
Montara Therapeutics — Montara Therapeutics is a precision-medicine neuroscience biotech startup improving safety and efficacy of therapies for people with neurological diseases

We are deep tech venture capital.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Fervo Energy — Fervo Energy delivers 24/7 carbon-free energy through development of next-generation geothermal projects.
Slip Robotics — Auto-load and auto-unload any truck in 5 minutes with SlipBots to drive 10X speed, safety, and savings across the supply chain. With Slip, truckers don't wait and forklift drivers don't risk it.

Backing founders building iconic companies that transcend boundaries

Investment focus

Software, SaaS, Health Care
Series A, Seed, Series B
United States, Canada, Germany

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Wherobots Inc. — Wherobots provides software solutions to enable every orgranization to drive value from data via geospatial location and time
Stainless — With Stainless, you can deliver idiomatic SDKs while you stay focused on building the API.

A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.

Investment focus

Software, Information Technology, Internet
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Team-GPT — Team-GPT helps companies use any AI model, find the right use cases for it, keep data safe, organize workflows, and track results. It speed up work with pre-made prompts, use cases, and editable AI Pages. Team-GPT is built with enterprise security, privacy, and compliance in mind from day one.
Chain Cat — Chain Cat is a discount marketplace for local life services. The company has developed a "digital + local life" life empowerment system that covers housing, food, transportation, and apparel, relying on key technologies including big data summary analysis, intelligent screening, and AI clever algorithms.
Enveda Biosciences — Enveda Biosciences is a biotechnology company building new medicines from plants. It harnesses the complexity of the natural world to tackle today’s biggest healthcare challenges. With the help of the advancements in knowledge graphs, machine learning, and metabolomics, they discover the next generation of small molecules. Its technologiessystematize the discovery of small molecules and novel targets for complex diseases. By probing novel chemical space and mechanisms of action, they are breaking the status quo for challenging diseases with a need for effective treatments, such as fibrosis or neurodegeneration.Enveda, launched in 2019, is based in San Francisco, California.

AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage

Investment focus

Health Care, Biotechnology, Software
Series A, Seed, Series B
United States, Cyprus, Ireland

Portfolio highlights

basys.ai — Basys.ai automates the process of prior authorization and utilization management to improve costs and timeliness for health plans/payers using an AI-based platform. The proprietary platform automates the process of encoding/digitizing the payer policies using machine learning, thus reducing the piloting timeline by up to 9 months.
Autonomize AI — AI Copilots for Healthcare & Life Sciences. Empower knowledge workers, reduce administrative burden and improve health outcomes.
Endless Health — We are a one-stop-shop for cardiovascular health. Empower yourself with research-backed info on your heart condition and how to prevent progression. Connect with a certified healthcare professional via video chat, messaging, and goal-setting to stay accountable. Stay in control of your health journey with a single dashboard that combines key dataand behavior tracking. Share with ease.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

Investment focus

Health Care, Software, Information Technology
Seed, Grant, Debt Financing
United States

Portfolio highlights

GrowFlux — GrowFlux, Inc. they offers a ecosystem of commercial scale wireless lighting controls, cloud services, and cloud connected agricultural sensors.
SFA Therapeutics — SFA Therapeutics is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.
Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.

Venture capital and technology investments

Investment focus

Software, Artificial Intelligence, E-Commerce
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Whatnot — Whatnot is a community marketplace where you can safely buy, sell, go live and geek out with collectors and other like-minded people. All items on Whatnot are verified. Shop on web or download the app.
Reflexivity — Say goodbye to stodgy terminals and clunky, decades-old interfaces. By asking questions in natural language, our institutional-grade analytic tools come alive and at your service.
Thread AI — Thread AI makes infrastructure simple for enterprises and can drive adoption and innovation in AI.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
United States, Canada

Portfolio highlights

Endogenex — DyaMX is an early stage medical device company focused on the treatment of Type 2 Diabetes
Synaptrix — Synaptrix is a medical device start-up company dedicated to developing and commercializing drug-free pain management solutions for postoperative joint surgery patients. The proprietary NOVABLOC system is a procedure-based solution that delivers a novel type of electrical stimulation. Human feasibili
AtaCor Medical — AtaCor Medical Inc., is a San Clemente-based medical device maker. It designs innovative solutions to deliver temporary, interim, and permanent cardiac pacing when, and where it matters most.

WE BACK HEROES using technology to solve the world's biggest problems

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Germany, Canada

Portfolio highlights

Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
Aalo Atomics — Creating abundant and dependable clean energy to power humanity for generations.
Waypoint Bio — Waypoint's proprietary spatial multi-omics platform enables us to solve critical issues around understanding how cell therapies navigate the three-dimensional tumor microenvironment and allow the measurement of cell-to-cell interactions.

Slow Ventures is a venture capital firm that focuses on investing in companies central to the technology industry as well as those operating at the intersection of science, society, and culture. The firm seeks to support innovative ideas and solutions that shape the future across various sectors.

Investment focus

Software, Internet, Health Care
Seed, Series A, Series B
United States, United Kingdom, Israel

Portfolio highlights

Prospinity — Prospinity provides the technical and legal infrastructure to make these success pools work.
Craftwork — Craftwork is a modern general contracting company that uses technology to simplify repair and renovation projects for homeowners.
Sublime Security — Sublime lets you write, run, and share rules to block phishing attacks, hunt for threats, and more.

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