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Top 50 Health Care Startup Investors in United States

A list of 50 angel investors and VC funds that invest in Health care startups based in United states. We rank investors based on the number of investments they made in Health care companies from United states. We update this investor list every month.

Top 50 Health Care Startup Investors in United States

Investor Health Care United States investments
Innova Memphis 132
ARCH Venture Partners 98
Khosla Ventures 92
New Enterprise Associates 91
Right Side Capital Management 89
Rock Health Capital 85
StartUp Health 80
Alumni Ventures 77
F-Prime Capital 77
Polaris Partners 73
Connecticut Innovations 73
OrbiMed 72
Gaingels 71
Canaan Partners 68
Alexandria Venture Investments 67
Atlas Venture 67
Versant Ventures 66
First Round Capital 66
BioAdvance 64
Lux Capital 63
5AM Ventures 62
Andreessen Horowitz 62
General Catalyst 61
Founders Fund 60
Third Rock Ventures 59
MPM Capital 59
Portfolia 57
SVA 56
BoxGroup 53
HealthTech Capital 52
Google Ventures 52
Wavemaker 360 50
Rev1 Ventures 48
Great Oaks Venture Capital 47
MB Venture Partners 47
Kleiner Perkins 47
DCVC 46
TEDCO 46
True Ventures 45
Felicis 45
Ben Franklin Technology Partners of Southeastern Pennsylvania 45
Hatteras Venture Partners 44
Fifty Years 44
Wisconsin Investment Partners 43
Slow Ventures 43
Greycroft 43
RA Capital Management 43
Boston Harbor Angels 42
Asset Management Ventures (AMV) 42
8VC 41
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Investor list
Innova Memphis VC Fund · Memphis, Tennessee, United States · 4 investments in the past 12 months
Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.
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Investment focus
  • Health Care, Medical, Medical Device
  • Seed, Pre-Seed, Convertible Note
  • United States, Argentina, United Kingdom
Portfolio highlights
  • Isomark Health — Isomark Health is a patented AI-based, real-time and 100% green breath technology that detects and prevents bacterial and viral infections.
  • Rantizo — Rantizo provides drone spraying systems and support services for custom applicators, agribusinesses and contractors. Elevating precision ag.
  • Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.
ARCH Venture Partners VC Fund · Chicago, Illinois, United States · 18 investments in the past 12 months
ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, China, Canada
Portfolio highlights
  • AIRNA — AIRNA is on a mission to transform the lives of patients with rare and common diseases by pioneering thediscovery and development of RNA editing therapeutics.
  • Generate Biomedicines — Generate Biomedicines is a biotechnological company focusing on creating breakthrough medicines.
  • Lightcast Discovery — Flexible control over droplet number, occupancy, location and movement. Enabling efficient, multi-step workflows with unprecedented flexibility.
Khosla Ventures VC Fund · Menlo Park, California, United States · 63 investments in the past 12 months
Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.
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Investment focus
  • Software, Health Care, Artificial Intelligence
  • Series A, Series B, Seed
  • United States, India, United Kingdom
Portfolio highlights
  • Aleph — Aleph helps top finance teams work with their data in real time. Businesses can automate financial models and streamline budgeting and forecasting with the fastest-to-implement FP&A platform. Aleph eliminates the need to export data from multiple sources by syncing spreadsheet models with data from 150+ integrations, and allows teams tointeract with their data in no-code dashboards.From annual budgeting to ad hoc reporting, scale your financial processes faster with better data without expanding your team. See why over 90% of people who start a trial with Aleph become customers!
  • Traba — Traba is on a mission to empower workers and local businesses to unlock their full productivity and earning potential.
  • Credit Genie — Credit Genie is a fintech company that provides financial tools and debt relief services. It helps Americans take control of their finances, by offering no-fee-or-interest cash advances between paydays, tools to get out of debt, and insights into their spending habits.
New Enterprise Associates VC Fund · Menlo Park, California, United States · 40 investments in the past 12 months
New Enterprise Associates, Inc. is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors, and geographies. With over $19 billion in cumulative committed capital since the firm’s founding in 1977, NEA invests in technology and healthcare companies at all stages in a company’slifecycle, from the seed stage through IPO. The firm's long track record of successful investing includes more than 210 portfolio company IPOs and more than 360 acquisitions.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series B, Series A, Series C
  • United States, India, China
Portfolio highlights
  • Meeno — Meeno is a relationship mentoring app powered by generative AI
  • Mojo Vision — Mojo Vision is a developer of augmented reality products and platforms intended to invent the future of computing. The company has developed a smart contact lens with a built-in display that gives timely information without interrupting the focus and delivers immediate, powerful, and relevant information without the intrusions of today'smobile devices, enabling users to connect with others at a glance, anytime, anywhere handsfree.Mojo Vision was founded in 2015 and headquartered in Saratoga, California.
  • Pulumi — Pulumi's open source infrastructure as code SDK enables you to create, deploy, and manage infrastructure on any cloud, using your favorite languages.
Right Side Capital Management VC Fund · San Francisco, California, United States · 6 investments in the past 12 months
Right Side Capital Management is a venture capital firm that helps startups build their company. It invests exclusively in the pre-seed round of technology startups and makes 75-100 investment per year. The firms prefers to invest in diversified technology sectors such as the internet and cloud companies.RSCM was established in 2010 and is basedin San Francisco, California.
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Investment focus
  • Software, SaaS, Health Care
  • Seed, Pre-Seed, Convertible Note
  • United States, Canada, United Kingdom
Portfolio highlights
  • OFFSITE — OFFSITE provides cloud computing and data center solutions.
  • Offsite — Offsite operates a platform that provides retreat planning for remote and hybrid teams. The company helps in the planning, management, and follow-up of team retreats, client-facing events, and other transformational, in-person experiences.
  • ZippedScript — ZippedScript is an application programming interface system developer that specializes in automatically verifying educational details. ZippedScript is located in Toronto, Ontario.
Rock Health Capital VC Fund · San Francisco, California, United States · 2 investments in the past 12 months
We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.
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Investment focus
  • Health Care, Software, Medical
  • Seed, Series A, Series B
  • United States, Denmark
Portfolio highlights
  • WellTheory — Our programs support autoimmune lifestyle changes with an actionable and supportive membership experience, no matter where you are in your autoimmune journey.
  • Oula Health — Oula is a modern maternity clinic combining the best of obstetrics and midwifery care to deliver an evidence-based and personalized pregnancy experience
  • Ribbon Health — Ribbon Health is building the infrastructure to transform healthcare decisions: with accurate and actionable provider information, including insurance coverage, prices, and performance.
StartUp Health VC Fund · New York, New York, United States · 11 investments in the past 12 months
Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots
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Investment focus
  • Health Care, Wellness, Medical
  • Seed, Funding Round, Pre-Seed
  • United States, Canada, United Kingdom
Portfolio highlights
  • AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
  • Medwise.ai — Medwise.ai is the Google for doctors.
  • Pear Suite — Pear Suite enables anyone—community health workers, other healthcare staff, and volunteers—to assess and address the social drivers of health for older adults in a scalable, cost-effective, and person-centered way.
Alumni Ventures VC Fund · Manchester, New Hampshire, United States · 101 investments in the past 12 months
Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.
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Investment focus
  • Software, Information Technology, Health Care
  • Seed, Series A, Series B
  • United States, United Kingdom, Canada
Portfolio highlights
  • 1up — 1up is a competitive AI for users to observe and understand everything their competitors are doing. 1up accelerates and automates the competitive experience for teams. 1up enables teams to save hours of manual effort in product, sales, and marketing, understand what their competitors are building and saying, and win competitive deals faster andeasier than ever before.
  • Cedar — Cedar is the operator of a platform designed to shorten the time between land acquisition and permitting. The web-based explorer of the company simplifies property search, site analysis, zoning, code compliance, and financial modeling, allowing clients to select the best design options for the site.
  • EarlyBird — EarlyBird simplifies investing for parents and elevates gifting by empowering friends and family to make meaningful investments to the children they love.
F-Prime Capital VC Fund · Cambridge, Massachusetts, United States · 30 investments in the past 12 months
F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.
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Investment focus
  • Health Care, Biotechnology, Medical
  • Series A, Series B, Series C
  • United States, United Kingdom, China
Portfolio highlights
  • Warmly — Instant information & unique details about everyone you meet with. Build rapport directly in Zoom. Absolutely free.
  • Doceree — Doceree is a pharmaceutical advertising & healthcare marketing company which helps in getting a better healthcare services
  • Avalyn Pharma — This does NOT display on the home page
Polaris Partners VC Fund · Boston, Massachusetts, United States · 16 investments in the past 12 months
Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.
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Investment focus
  • Health Care, Biotechnology, Medical
  • Series B, Series A, Series C
  • United States, Singapore, Ireland
Portfolio highlights
  • Tausight — Tausight is specifically designed to help Healthcare ensure the confidentiality, integrity, and availability of ePHI.
  • Triveni Bio — Triveni Bio is pioneering a genetics-informed precision medicine approach to develop functional antibodies to treat immunological and inflammatory disorders.
  • Engine Biosciences — We digitize and decipher complex biology with cutting-edge technologies to discover and develop life-changing medicines.
Connecticut Innovations VC Fund · Rocky Hill, Connecticut, United States · 10 investments in the past 12 months
At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.
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Investment focus
  • Health Care, Biotechnology, Software
  • Seed, Series A, Funding Round
  • United States, Israel, Canada
Portfolio highlights
  • Slooh — Explore space in real-time from your home using slooh online telescopes. Learn about the different objects in our solar system, track asteroids and deep sky objects like nebulas, galaxies, etc. Teachers, Students, and Astronomers can work together to observe and photograph astronomical objects.
  • Anonybit — Anonybit offers top-notch identity protection & secure authentication solutions. Experience the power of decentralized biometric security for enhanced privacy.
  • Modifi Bio — Modifying DNA toEradicate Cancer At Modifi Bio, we are changing the oncology treatment paradigm. Bypassing the conventional approach of indirectly targeting proteins in cancer cells, Modifi Bio is redefining the rules of oncology treatment: eradicating cancer via direct DNA modification. Our novel platform demonstrates powerful anti-tumor activity in glioma and many other cancers with intrinsic
OrbiMed VC Fund · New York, New York, United States · 39 investments in the past 12 months
Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series B, Series A, Series C
  • United States, China, Israel
Portfolio highlights
  • Triveni Bio — Triveni Bio is pioneering a genetics-informed precision medicine approach to develop functional antibodies to treat immunological and inflammatory disorders.
  • Rampart Bioscience — Rampart Bioscience develops gene medicines to provide long-lasting treatments for a wide range of diseases. It also offers proprietary development and delivery platforms, which together, create optimized therapeutics in a revocable, non-viral format. It also assists patients with genetically driven diseases by integrating capabilities from avariety of key scientific disciplines including gene delivery, protein sciences, and clinical translation.
  • Terremoto Biosciences — By unleashing the power of covalent chemistry, we can deliver superior small molecule medicines with enhanced therapeutic benefit.
Gaingels VC Fund · New York, New York, United States · 91 investments in the past 12 months
Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.
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Investment focus
  • Software, Health Care, FinTech
  • Seed, Series A, Series B
  • United States, Canada, Germany
Portfolio highlights
  • Finerio Connect — Finerio is an automated and free personal finance platform in Mexico. Finerio allows users to link debit and credit accounts of the most important banks in Mexico while providing them insights on how to financially plan and save money.
  • Pair Team — Pair Team is on a mission to build the primary care infrastructure for America’s most vulnerable communities.They are the first tech-enabled care team that empowers safety-net primary care systems and the Medicaid & Medicare patients they serve. They act as an extension of the clinical staff to provide a personalized, high-touch careexperience while addressing patients' barriers to care such as lack of transportation, housing/food insecurity, and mobile phone access. Internally, they are building a unique care delivery platform to ensure clinical best practices, integrate care with community-based organizations, and automate administrative work so that clinicians can focus on time with our patients.
  • Finerio — Finerio is the first automated and free personal finance app in Mexico.
Canaan Partners VC Fund · Menlo Park, California, United States · 16 investments in the past 12 months
Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.
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Investment focus
  • Software, Biotechnology, Health Care
  • Series A, Series B, Series C
  • United States, Israel, India
Portfolio highlights
  • Acesion Pharma — Acesion Pharma ApS is a Danish biotech company founded in 2011 and based in Copenhagen. Acesion Pharma develops more efficacious and safe drugs for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia.
  • Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.
  • AgomAb Therapeutics — AgomAb is developing molecular therapies for the regeneration of damaged tissues. Their unique agonistic monoclonal antibody molecules (“agomAbs”) stimulate molecular and cellular repair mechanisms that have the potential to restore organ function in patients with fibrotic, inflammatory, autoimmune and degenerative diseases.
Alexandria Venture Investments VC Fund · Pasadena, California, United States · 18 investments in the past 12 months
Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, France, Canada
Portfolio highlights
  • Triveni Bio — Triveni Bio is pioneering a genetics-informed precision medicine approach to develop functional antibodies to treat immunological and inflammatory disorders.
  • Deka Biosciences — Deka BioSciences, Inc. is committed to developing and delivering life-changing medicines to patients with cancer and inflammatory diseases.
  • Arialys Therapeutics — Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience. The company focuses on how the immune system impacts CNS health, disease, and treatment.
Atlas Venture VC Fund · Cambridge, Massachusetts, United States · 8 investments in the past 12 months
Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, United Kingdom, Canada
Portfolio highlights
  • Aiolos Bio — Long Description: Aiolos Bio is a biotech company focused on developing therapies for respiratory diseases like asthma as well as other immune conditions. The company is initially focused on advancing AIO-001, a monoclonal antibody therapy for moderate-to-severe asthma that only requires dosing every 6 months. Aiolos Bio was founded by anaccomplished team with decades of drug development experience and leadership in the biotech industry.
  • Triveni Bio — Triveni Bio is pioneering a genetics-informed precision medicine approach to develop functional antibodies to treat immunological and inflammatory disorders.
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
Versant Ventures VC Fund · Menlo Park, California, United States · 7 investments in the past 12 months
Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series A, Series B, Series C
  • United States, Switzerland, Canada
Portfolio highlights
  • Kate Therapeutics — Kate Therapeutics is a patient-focused biotechnology company developing AAV-based gene therapies to treat genetically defined muscle and heart diseases.
  • Nexo Therapeutics — Nexo Therapeutics is a small molecule oncology company dedicated to the discovery and development of new drugs for cancer patients who currently lack meaningful therapies.
  • Tentarix Biotherapeutics — Tentarix creates innovative protein therapeutics with uniquely combined bioactivities that leverage synthetic biology. The company develops a protein engineering platform designed for multispecific therapies.
First Round Capital VC Fund · San Francisco, California, United States · 17 investments in the past 12 months
First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.
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Investment focus
  • Software, E-Commerce, Health Care
  • Seed, Series A, Series B
  • United States, Canada, India
Portfolio highlights
  • Cymbal — The human readable block explorer. Explore any wallet, NFT or collection to understand their activity, all in real time.
  • Spline — Spline is a free 3D design software with real-time collaboration to create web interactive experiences in the browser. Easy 3d modeling, animation, textures, and more.
  • Ossium Health — Ossium is building the world's first bone marrow bank to treat blood cancers, improve organ transplantation, and repair damage from radiation.The cells of the immune system are the human body’s natural defenders against disease. At Ossium, they are developing better methods of recovering, preserving, deploying these critical cells to keepdisease at bay.
BioAdvance VC Fund · Philadelphia, Pennsylvania, United States · 3 investments in the past 12 months
BioAdvance actively invests venture capital in therapies, medical devices, research tools, diagnostics and health IT in the Mid-Atlantic region.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Seed, Funding Round, Series A
  • United States, Canada
Portfolio highlights
  • Senzo — SENZO HEALTH HAS DEVELOPED A REVOLUTIONARY LATERAL FLOW TEST WHICH DELIVERS THE SAME ACCURACY AS LABORATORY-BASED PCR, WITH RESULTS AVAILABLE WITHIN 10 MINUTES, AT A FRACTION OF THE COST.
  • KayoThera — KayoThera is a biotechnology company developing therapeutics used to cure late-stage and metastatic cancers. Its programs work on inhibiting a key enzyme that is responsible for protecting the cancer cells and depleting regulatory T-cells that intends to cure hitherto incurable cancers and give hope to patients. The company's mission is todevelop the first-in-class immuno- and targeted therapies to drive cures in advanced cancersKayoThera was founded in 2019 and is headquartered in Princeton, New Jersey.
  • Palvella Therapeutics — Palvella Therapeutics is committed to developing safe and effective therapies that specifically target the root cause of genetic skin diseases.
Lux Capital VC Fund · New York, New York, United States · 33 investments in the past 12 months
Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series A, Seed, Series B
  • United States, Canada, United Kingdom
Portfolio highlights
  • Modal Labs — Modal develops machine learning software to help run code in the cloud. The software enables users to run or deploy machine learning models, massively parallel compute jobs, task queues, web apps, and more. It also writes the code to launch hundreds of custom containers and runs scripts in the cloud faster than on the local machine.
  • Delphi — Delphi is digital cloning that scales time, monetizes knowledge, and interacts audience at scale.
  • Factory — The machine that builds the machine.
5AM Ventures VC Fund · Menlo Park, California, United States · 3 investments in the past 12 months
5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States, Switzerland, Canada
Portfolio highlights
  • Spruce Biosciences — Developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need
  • Nvelop Therapeutics — Nvelop Therapeutics is a biotechnology company that provides gene editing technology services for unmet major disease needs.
  • Precede Biosciences — Precede Biosciences is revolutionizing precision medicine by revealing unprecedented insights into disease-defining biology from a simple blood test. Discover how we are helping create a world where medicine is developed more successfully, and every diagnosis is precise and minimally invasive.
Andreessen Horowitz VC Fund · Menlo Park, California, United States · 122 investments in the past 12 months
Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.
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Investment focus
  • Software, Information Technology, Internet
  • Series A, Seed, Series B
  • United States, United Kingdom, Canada
Portfolio highlights
  • Klu.ai — Klu.ai is a generative AI platform that simplifies the process of designing, deploying, and optimizing AI applications.The company integrates major large language models (LLMs) such as Anthropic Claude, Azure OpenAI, GPT-4, and over 15 other models, enabling rapid prompt/model experimentation, data gathering, and user feedback. The platformoffers features like Klu Actions for content generation, business operations workflows, content analysis, and summarization, as well as optimization techniques for A/B testing and fine-tuning support for models like OpenAI's GPT-3.5 Turbo and GPT-4. Klu.ai is committed to data privacy and security, providing data obfuscation and redaction features to protect sensitive information.Klu.ai is founded by Stephen M. Walker II in 2022 and is located in San Francisco, California.
  • Waymark — Waymark is a company dedicated to improving access and quality of care for people receiving Medicaid.
  • Gate Bioscience — Gate Bioscience is developing Molecular Gates, a new frontier in protein elimination. Molecular Gates are small molecule drugs that selectively eliminate harmful extracellular proteins at their origin, inside cells, and prevent them from emerging to cause disease.
General Catalyst VC Fund · Cambridge, Massachusetts, United States · 74 investments in the past 12 months
Investing in powerful, positive change that endures
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Investment focus
  • Software, Health Care, Internet
  • Series A, Series B, Seed
  • United States, United Kingdom, India
Portfolio highlights
  • Deasie — Deasie ensures that only relevant, high-quality, and safe data is fed into language models.
  • Nova Credit — Nova Credit is a consumer credit bureau that connects consumers and lenders with trusted data and analytics to expand access to credit.
  • Samara — Discover Samara's Backyard accessory dwelling units. Elevated design, expertly crafted. Fast and easy installation. Solar-powered and future-ready.
Founders Fund VC Fund · San Francisco, California, United States · 43 investments in the past 12 months
Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.
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Investment focus
  • Software, Health Care, FinTech
  • Series A, Seed, Series B
  • United States, United Kingdom, Germany
Portfolio highlights
  • Opal — Opal makes it easy to look and sound professional on video calls. We built the Opal C1, the first professional camera and Composer, the best video editing camera software companion.
  • Traba — Traba is on a mission to empower workers and local businesses to unlock their full productivity and earning potential.
  • Wraithwatch — Wraithwatch is building the next generation of cyber defense for the United States and its allies.
Third Rock Ventures VC Fund · Boston, Massachusetts, United States · 5 investments in the past 12 months
Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series A, Series B, Series C
  • United States
Portfolio highlights
  • Flare Therapeutics — Flare Therapeutics is a biotechnology company opening up a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders, Flare’s team has uncovered ‘switch sites,’ druggable regions that are key targets fortranscription factor regulation to address mutations that cause disease. Our drug discovery to target switch sites has rapidly advanced, resulting in an emerging pipeline of drug programs that address well-validated transcription factors, initially focused on precision oncology with future potential in neurology, rare genetic disorders, immunology, and inflammation.
  • Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
  • CARGO Therapeutics — CARGO Therapeutics develops CAR T-cell therapy to overcome cancer treatment resistance and address access barriers so that more patients can benefit from potentially curative therapies. The company is on a mission to outwit cancer by developing best-in-class chimeric antigen receptor (CAR) T-cell therapies. Despite commercially available autologousCARs advancements, these treatments are curative for less than half of all cancer patients. Furthermore, far too many patients are unable to access these potentially curative therapies due to other obstacles such as manufacturing, supply constraints, long turnaround times, and reimbursement barriers. CARGO's team is intensely focused on pursuing novel solutions to improve cancer treatment outcomes and experiences.
MPM Capital VC Fund · Cambridge, Massachusetts, United States · 7 investments in the past 12 months
Powering Breakthroughs in Life Sciences
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Investment focus
  • Biotechnology, Health Care, Pharmaceutical
  • Series B, Series A, Series C
  • United States, Canada, Germany
Portfolio highlights
  • Deka Biosciences — Deka BioSciences, Inc. is committed to developing and delivering life-changing medicines to patients with cancer and inflammatory diseases.
  • ReCode Therapeutics — ReCode is the first genetic medicines platform to enable highly targeted delivery to organs, tissues and cells beyond the liver. Our pipeline of rare disease therapeutics uses optimized mRNA and gene correction with redosing capability.
  • Arialys Therapeutics — Arialys Therapeutics is a pre-clinical stage company that develops auto-antibody focusing on neuroscience. The company focuses on how the immune system impacts CNS health, disease, and treatment.
Portfolia VC Fund · San Mateo, California, United States · 16 investments in the past 12 months
Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact
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Investment focus
  • Health Care, Software, Biotechnology
  • Seed, Series A, Series B
  • United States, Canada, Argentina
Portfolio highlights
  • Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
  • Prime Roots — Prime Roots is on a mission to provide a better cut of meat for every type of eater. Rooted in koji, Prime Roots is able to replicate the taste and texture of meat without any of the environmental costs of animal proteins.
  • Carbice Corporation — Carbice is the first no-compromise thermal interface material. It achieves all the advantages of both solid and liquid thermal interface materials without any of the pitfalls.
SVA VC Fund · San Francisco, California, United States · 41 investments in the past 12 months
SV Angel is a San Francisco-based venture fund. Their experience spans helping companies like Airbnb, Coinbase, Databricks, DoorDash, Faire, Flexport, GitHub, Notion, Pinterest, Snap, Square, and Stripe Scale. Over the last 30 years of investing, their core values of trust, loyalty, and integrity along with a founder-first approach have driven ourstrategy. They are a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.
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Investment focus
  • Software, Internet, Mobile
  • Seed, Series A, Series B
  • United States, Canada, United Kingdom
Portfolio highlights
  • Induced AI — Induced is an AI-native browser RPA platform that lets users combine browsing and web tools, along with smart reasoning and memory, to automate enterprise workflows of all kinds.
  • Samara — Discover Samara's Backyard accessory dwelling units. Elevated design, expertly crafted. Fast and easy installation. Solar-powered and future-ready.
  • Factory — The machine that builds the machine.
BoxGroup VC Fund · New York, New York, United States · 40 investments in the past 12 months
BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com
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Investment focus
  • Software, Health Care, Internet
  • Seed, Series A, Series B
  • United States, France, Mexico
Portfolio highlights
  • Basis — Basis operates as an AI platform built specifically for accounting firms.
  • Factory — The machine that builds the machine.
  • Prophetic AI — Prophetic AI is a non-invasive neurotech company that offers neural devices to help people stabilize and induce lucid dreaming.
HealthTech Capital VC Fund · Los Altos Hills, California, United States
Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups
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Investment focus
  • Health Care, Medical Device, Medical
  • Seed, Series A, Convertible Note
  • United States
Portfolio highlights
  • Agile Therapeutics — Agile Therapeutics, Inc., a specialty pharmaceutical company, engages in the development of women's healthcare products. It offers a low estrogen dose seven-day transdermal contraceptive patch system that delivers a combination of levonorgestrel and Ethinylestradiol. The company was founded in 1997 as Levotech, Inc. and changed its name toAgile Therapeutics, Inc. in April 2001. It is based in Princeton, New Jersey.
  • GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
  • Wavely Diagnostics — Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.
Google Ventures VC Fund · Mountain View, California, United States · 63 investments in the past 12 months
GV supports innovative founders moving the world forward.
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Investment focus
  • Software, Health Care, Biotechnology
  • Series A, Series B, Seed
  • United States, United Kingdom, Canada
Portfolio highlights
  • Censys — Exposure Management, External Attack Surface Management, and Threat Hunting solutions powered by the most comprehensive dataset of internet intelligence.
  • Signos — For your personalized weight loss journey, Signos gives you simple actions to improve your health. See your data from the Continuous Glucose Monitor (CGM) device in our easy-to-use app!
  • Gate Bioscience — Gate Bioscience is developing Molecular Gates, a new frontier in protein elimination. Molecular Gates are small molecule drugs that selectively eliminate harmful extracellular proteins at their origin, inside cells, and prevent them from emerging to cause disease.
Wavemaker 360 VC Fund · Pasadena, California, United States · 6 investments in the past 12 months
Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.
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Investment focus
  • Health Care, Medical, Medical Device
  • Seed, Series A, Funding Round
  • United States, United Kingdom, Canada
Portfolio highlights
  • 32Co — 32Co is a medical technology platform that helps general dentists deliver clear aligner orthodontics to their patients.
  • Essenvia — Rapidly submit eSTAR, EUMDR and IVDR applications, eliminate errors and accelerate approvals with the only regulatory submission platform made for MedTech
  • Gradient Health — One of the biggest barriers to accelerating AI development is access to large datasets of labeled pathologies.
Rev1 Ventures VC Fund · Columbus, Ohio, United States · 8 investments in the past 12 months
Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!
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Investment focus
  • Software, Health Care, Information Technology
  • Seed, Series A, Funding Round
  • United States, Germany
Portfolio highlights
  • Lentechs — CREATING A NEW VISION LENTECHS is a privately-held, clinical-stage, ophthalmic medical device company in Columbus, Ohio dedicated to improving vision at every stage of life through innovative design and breakthrough contact lens technology. LENTECHS is focused on developing a patented, first-of-its-kind line of soft, suspended contact lens designed to deliver exceptional, glasses-like vision at all
  • ConverSight — ConverSight.ai is artificial intelligence and analytics-based platform that uncovers actionable business insights for enterprises through natural language conversations and enables them to take action instantly. The platform generates tremendous efficiencies across organizational hierarchies from junior to senior leadership, reducing our customerreport generation costs by over 50%.The company was founded in 2017 and is headquartered in Indianapolis.
  • Print Syndicate — Print Syndicate is an apparel and home goods company that offers its consumers access to timely, curated, and well-designed products that allow them to express who they are. The company's design team interprets and converts social trends into digital designs, which are then printed on objects including apparel, phone cases, and housewares.Itwas founded in 2012 and headquartered in Columbus, Ohio.
Great Oaks Venture Capital VC Fund · New York, New York, United States · 11 investments in the past 12 months
Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.
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Investment focus
  • E-Commerce, Software, Health Care
  • Seed, Series A, Series B
  • United States, United Kingdom, Spain
Portfolio highlights
  • Leverage — Answering the Fundamental Question: "Where
  • Lex — Lex is a lo-fi, text-based social app for womxn, trans, genderqueer, intersex, two spirit, and non-binary people for meeting lovers and friends. Lex—short for lexicon—is the only social app where the text comes first and the selfies, second.
  • Dashy Dash — Dashy Dash is a free community powered tool that makes it easy to manage invoices, discover new products & compare prices to help you save money.
MB Venture Partners VC Fund · Memphis, Tennessee, United States
MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases
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Investment focus
  • Health Care, Medical, Medical Device
  • Seed, Series B, Series C
  • United States, Israel
Portfolio highlights
  • Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
  • SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
  • Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.
Kleiner Perkins VC Fund · Menlo Park, California, United States · 15 investments in the past 12 months
Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley.
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Investment focus
  • Software, Health Care, Information Technology
  • Series B, Series A, Series C
  • United States, China, United Kingdom
Portfolio highlights
  • Captions — Say hello to Captions, the only camera and editing app that automatically transcribes, captions and clips your talking videos for you.
  • Flagship — Flagship develops a SaaS data science solution that brings predictive machine-learning intelligence to retail. Its centralized platform helps businesses make timely, data-driven decisions across internal stakeholders and channels. Flagship enriches retail brands' first-party data with machine learning algorithms to optimize customer retention,inventory sell-through, and revenue.
  • Lightforce Orthodontics — LightForce Orthodontics, founded in 2015, makes the world’s first and only fully customized 3D-printed bracket system that is based on the anatomy and tooth morphology of each patient. The company’s mission is to apply modern technology and mass-customization to improve the orthodontic experience for both patients and doctors. LightForce’s platformunites the latest in digital treatment capabilities with cutting-edge, on-demand, 3D manufacturing to offer clinicians the first significant advancement in bracket-based treatment protocol in the past 50 years. A first-of-its-kind in the orthodontic space, Lightforce offers an unparalleled platform for orthodontists and LightForce technicians to collaborate on treatment plans for each individual patient. The company’s solution significantly reduces patient visits to the orthodontist and time spent wearing braces by providing 100 percent fully-customized solutions that improve both convenience and quality, ensuring patients receive the gold standard of care.
DCVC VC Fund · San Francisco, California, United States · 23 investments in the past 12 months
We are deep tech venture capital.
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Investment focus
  • Software, Artificial Intelligence, Health Care
  • Seed, Series A, Series B
  • United States, Canada, United Kingdom
Portfolio highlights
  • Noetik — Noetik is an AI-native biotechnology company. Our mission is to leverage advanced machine learning methods to discover and develop cancer immunotherapies.
  • Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.
  • Reality Defender — Reality Defender is deepfake detection done right. With billions of visual and audio assets indexed, we offer the most robust deepfake detection available.
TEDCO VC Fund · Columbia, Maryland, United States · 7 investments in the past 12 months
TEDCO was created by the Maryland State Legislature in 1998 to facilitate the transfer and commercialization of technology from Maryland’s research universities and federal labs into the marketplace and to assist in the creation and growth of technology-based businesses in all regions of the State. TEDCO is an independent organization thatstrives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy. In Maryland and beyond, TEDCO is a resource of mentoring, funding and networking for entrepreneurs and start-ups that need guidance as they bring innovative concepts to market. TEDCO is more than an early stage funding resource. It is the hub of Maryland’s entrepreneurial network where startups find mentors, organizational assistance, facilities for daily operations, and a roadmap for success.
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Investment focus
  • Software, Health Care, Biotechnology
  • Seed, Pre-Seed, Series A
  • United States
Portfolio highlights
  • Hopr — Hopr recognizes the increasing relevance of cybersecurity in today's global digital society. Hopr objective is to assist organizations in protecting their digital operations and data by rethinking old challenges and then developing innovative cybersecurity solutions to tackle them.
  • Fem Equity — Fem Equity is a work platform that develops real-time solutions for women and underrepresented professionals experiencing salary or professional inequalities.
  • N5 Sensors — Sensors and solutions for protecting lives and infrastructure from environmental hazards.
True Ventures VC Fund · Palo Alto, California, United States · 32 investments in the past 12 months
A Silicon Valley-based venture capital firm focused on early stage technology startups. We invest in brilliant people who bring ideas that matter to life.
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Investment focus
  • Software, Information Technology, Internet
  • Series A, Seed, Series B
  • United States, United Kingdom, Finland
Portfolio highlights
  • Seurat Technologies — Seurat Technologies, Inc. was incorporated in 2015. Main offices in Wilmington, MA
  • RadiantGraph — RadiantGraph is on a mission to make healthcare more accessible and user-friendly for all of us. AI technology assists top healthcare organizations in developing deeper and more meaningful connections with their patients, resulting in tailored engagement and therapeutic outcomes.
  • Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.
Felicis VC Fund · Menlo Park, California, United States · 29 investments in the past 12 months
Backing founders building iconic companies that transcend boundaries
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Investment focus
  • Software, SaaS, Health Care
  • Series A, Seed, Series B
  • United States, Canada, Germany
Portfolio highlights
  • Opsera — Opsera automates any CI/CD toolchain, enables declarative pipelines, and provides unified insights across your entire software delivery process.
  • Warmly — Instant information & unique details about everyone you meet with. Build rapport directly in Zoom. Absolutely free.
  • Oro Labs — A supplier management tool that can flex and scale with evolving business needs.
Ben Franklin Technology Partners of Southeastern Pennsylvania VC Fund · Philadelphia, Pennsylvania, United States
We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.
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Investment focus
  • Health Care, Software, Information Technology
  • Seed, Grant, Debt Financing
  • United States
Portfolio highlights
  • Yellowdig — Yellowdig offers educators a gameful learning digital solution to improve student engagement by building learning communities.
  • ImpactableX — The social impact modeling & management toolkit behind leading solutions to our world's most pressing challenges.
  • GrowFlux — GrowFlux, Inc. they offers a ecosystem of commercial scale wireless lighting controls, cloud services, and cloud connected agricultural sensors.
Hatteras Venture Partners VC Fund · Durham, North Carolina, United States · 8 investments in the past 12 months
Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.
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Investment focus
  • Biotechnology, Health Care, Medical
  • Series A, Series B, Funding Round
  • United States, Canada
Portfolio highlights
  • 410 Medical — 410 Medical has developed a simple, intuitive solution that allows a single healthcare provider to rapidly deliver fluid to critically ill patients, improving care, and saving lives. Their device allows fast set-up, improves resuscitation speed, minimizes provider fatigue, and frees providers to address other patient care issues simultaneously.This solution is particularly useful in pre-hospital settings and the emergency department and where speed is critical and resources may be limited.It was founded in 2013 and headquartered in Durham, North Carolina.
  • Myeloid Therapeutics — Myeloid Therapeutics is an immunology company focused on combining immunologic insights with cutting-edge technologies to harness myeloid cells to eradicate cancer and other diseases. The Company's ATAKTM platform technology can be broadly applied, and it is initially advancing a cell therapy program for T cell lymphoma and a primed monocyteapproach to treat glioblastoma. The ATAK platform is scalable to multiple treatment modalities and other disease areas in collaboration with partners.
  • Veralox Therapeutics — Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes. Based on an understanding of the molecular mechanisms of these diseases, these efforts will lead to new treatment paradigms and better outcomes for patients.
Fifty Years VC Fund · San Francisco, California, United States · 10 investments in the past 12 months
WE BACK HEROES using technology to solve the world's biggest problems
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Investment focus
  • Biotechnology, Health Care, Medical
  • Seed, Series A, Series B
  • United States, Germany, Canada
Portfolio highlights
  • Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
  • BIOS — BIOS Health is unlocking the potential of the nervous system in treating chronic disease by using AI-powered neural interfaces that can automatically read and write neural signals.
  • Elicit — Elicit is an artificial intelligence research assistant that uses language models to help users automate research workflows. This research assistant finds relevant papers without a perfect keyword match, summarizes takeaways from the papers, and extracts key information from the papers.
Wisconsin Investment Partners VC Fund · Madison, Wisconsin, United States · 4 investments in the past 12 months
Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.
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Investment focus
  • Health Care, Biotechnology, Medical
  • Funding Round, Seed, Series A
  • United States, Canada, United Kingdom
Portfolio highlights
  • Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
  • BeeReaders — ## Build Setup
  • Midwest Games — Midwest Games GREAT GAMES CAN COME FROM ANYWHERE. Let's change where games come from!
Slow Ventures VC Fund · San Francisco, California, United States · 17 investments in the past 12 months
Slow Ventures is a community built on the collective experience and fueled by curiosity, Slow understands the entrepreneurial journey. Investing at the center of technology and on the edges of science, society, and culture, Slow gives founders the resources, connections, experiences, and empathy required to build strong, sustainable companies.
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Investment focus
  • Software, Internet, Health Care
  • Seed, Series A, Series B
  • United States, Israel, United Kingdom
Portfolio highlights
  • KINO — KINO is a film production company that brings fans behind the scenes of their favorite hollywood films.
  • Gleen AI — Delight your customers. Get Gleen, the world's most accurate & capable generative AI-based chatbot. Trustworthy answers. Automatic actions. Unify knowledge.
  • Metropolis — Metropolis unites technology and operations to make parking remarkable.
Greycroft VC Fund · New York, New York, United States · 29 investments in the past 12 months
Venture capital and technology investments
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Investment focus
  • Software, E-Commerce, Internet
  • Series A, Seed, Series B
  • United States, United Kingdom, Germany
Portfolio highlights
  • CNaught — CNaught is an online platform that helps companies to purchase a diversified portfolio of carbon offsets.
  • Riffusion — Riffusion allows users to make short music clips with AI-generated vocals.
  • Vera — Vera develops an assessment platform to identify and address risks in artificial intelligence and machine learning models. It engages key stakeholders across teams to create data-driven assessments and use data science tools to investigate AI and ML models, helping organizations navigate through uncertainty and protecting companies and individualsfrom risky artificial intelligence systems.
RA Capital Management VC Fund · Boston, Massachusetts, United States · 46 investments in the past 12 months
RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.
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Investment focus
  • Biotechnology, Health Care, Therapeutics
  • Series B, Series A, Series C
  • United States, United Kingdom, China
Portfolio highlights
  • Aiolos Bio — Long Description: Aiolos Bio is a biotech company focused on developing therapies for respiratory diseases like asthma as well as other immune conditions. The company is initially focused on advancing AIO-001, a monoclonal antibody therapy for moderate-to-severe asthma that only requires dosing every 6 months. Aiolos Bio was founded by anaccomplished team with decades of drug development experience and leadership in the biotech industry.
  • Rampart Bioscience — Rampart Bioscience develops gene medicines to provide long-lasting treatments for a wide range of diseases. It also offers proprietary development and delivery platforms, which together, create optimized therapeutics in a revocable, non-viral format. It also assists patients with genetically driven diseases by integrating capabilities from avariety of key scientific disciplines including gene delivery, protein sciences, and clinical translation.
  • Harpoon Therapeutics — Harpoon Therapeutics is a clinical-stage immunotherapy company developing a novel class of T cell engagers that harness the power of the body’s immune system to treat patients suffering from cancer and other diseases. T cell engagers are engineered proteins that direct a patient’s own T cells to kill target cells that express specific proteins, orantigens, carried by the target cells. Using its proprietary Tri-specific T cell Activating Construct (TriTAC), platform, Harpoon is developing a pipeline of novel T cell engagers, or TriTACs, initially focused on the treatment of solid tumors and hematologic malignancies. Harpoon's first drug candidate, HPN424, is currently in Phase 1 clinical trial as a treatment for prostate cancer.
Boston Harbor Angels VC Fund · Boston, Massachusetts, United States
Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.
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Investment focus
  • Biotechnology, Health Care, Medical Device
  • Angel, Seed, Series A
  • United States, Canada, India
Portfolio highlights
  • Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
  • Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
  • Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.
Asset Management Ventures (AMV) VC Fund · Palo Alto, California, United States
AMV is the leading early-stage venture capital firm investing in digital health, technology and life sciences. It has assembled the leading early-stage
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Investment focus
  • Health Care, Biotechnology, Software
  • Series A, Seed, Series B
  • United States, Cyprus, Ireland
Portfolio highlights
  • SubjectWell — SubjectWell connects patients with chronic health conditions to trials and treatments. Since 2012, SubjectWell has been registering tens of millions of healthcare-motivated patients with known conditions. At SubjectWell, we already have the patients you need.
  • Autonomize AI — Autonomize AI is a human-centric AI platform that learns from multi-structured clinical and biomedical data and pairs it with human context to aid decision-making and data discovery. They extract contextual information from multi-structured healthcare data, enrich with human know-how, and aid decision-making and data discovery.
  • Carta Healthcare — Our industry-leading, AI-driven technology converts both structured and unstructured healthcare data into a high-quality, reliable, standardized dataset that can be used across your organization.
8VC VC Fund · San Francisco, California, United States · 39 investments in the past 12 months
8VC seeks to enable industry transformation. In a wave of creative destruction, they believe emerging platforms will replace the decades-old technology infrastructure behind many industries, promoting greater innovation and prosperity.
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Investment focus
  • Software, Health Care, Artificial Intelligence
  • Seed, Series A, Series B
  • United States, Canada, Colombia
Portfolio highlights
  • Saronic — Providing naval and maritime forces with the most intelligent Autonomous Surface Vessels available.
  • ClearFeed — Conversational Support Platform on Slack
  • Samara — Discover Samara's Backyard accessory dwelling units. Elevated design, expertly crafted. Fast and easy installation. Solar-powered and future-ready.
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