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Top 20 Biotech Startup Investors in Estonia (June 2026)

The most active venture capital funds and angel investors investing in Estonia Biotech startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in Estonia Biotech startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Prototron
VC Fund
3 Estonia, Finland, Germany Pre-Seed, Grant, Seed Software, Manufacturing, Internet of Things $3k–$27k
Enterprise Estonia
VC Fund
3 Estonia Grant, Seed, Pre-Seed Biotechnology, Software, Mobile Apps $16k–$4.3M
Voima Ventures
VC Fund
2 Finland, Sweden, Norway Seed, Pre-Seed, Series A Biotechnology, Health Care, Artificial Intelligence $439k–$18M
Nordic Foodtech VC
VC Fund
2 Finland, Sweden, Denmark Seed, Series A Biotechnology, Life Science, Water $549k–$18M
SOSV
VC Fund
1 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
AS AMALFI
Angel
1 Estonia Pre-Seed Biotechnology
Estonian Research Council
VC Fund
1 Estonia Seed Biotechnology
Johanna Britt Berzin
Angel
1 Estonia Pre-Seed Biotechnology
Robert Laud
Angel
1 Estonia Pre-Seed Biotechnology
Ivo Remmelg
Angel
1 Estonia, Latvia, Norway Seed, Angel, Pre-Seed Mobile, Sports, FinTech
Timo Rein
Angel
1 Estonia, Finland, United Kingdom Seed, Angel, Convertible Note Software, Recruiting, Human Resources $280k–$1.2M
Domain Associates
VC Fund
1 United States, Canada, Estonia Series B, Series C, Series A Biotechnology, Health Care, Medical $3.8M–$60M
Johnson & Johnson Development Corporation
VC Fund
1 United States, United Kingdom, Canada Series C, Series B Health Care, Biotechnology, Medical $12M–$49M
Hugues Flament
Angel
1 Estonia Pre-Seed Biotechnology
Siim Sikkut
Angel
1 Estonia Pre-Seed Biotechnology
Crosslight Partners
VC Fund
1 Sweden, Estonia Seed Biotechnology, B2B, Medical
Change Ventures
VC Fund
1 Estonia, Latvia, Lithuania Seed, Pre-Seed, Series A Software, Information Technology, Apps $273k–$33M
Specialist VC
VC Fund
1 Estonia, United Kingdom, Finland Seed, Pre-Seed Software, Information Technology, Artificial Intelligence $241k–$6.5M
Peep Vain
Angel
1 Estonia Seed, Angel Software, Genetics, Recruiting
Grid.vc
VC Fund
1 Finland, Estonia Seed, Pre-Seed Energy, Renewable Energy, SaaS $20k–$6.3M
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Investor list

Prototron
VC Fund · Tallinn, Harjumaa, Estonia · 3 investments in Estonia Biotech startups

Prototron is a start-up fund that gives money to teams for turning their great ideas into the first working prototype. Founded in 2012 by Swedbank, Tallinn Technical University and Tallinn Science Park Tehnopol. We finance teams with high growth potential in areas of Greentech, Electronics, Mechatronics and ICT. We run 3-4 rounds of financingevery year. During last 5 years we've funded 58 startups with over 470'000€ in cash + coaching/incubation services. Our protfolio has generated >4,5 M€ revenue and raised >17'000'000€ capital. These results make Prototron the most productive pre-seed fund in Estonia. Do you want to be part of the success? We seek for: *) New start-up teams who need money for building a prototype. Apply for funding: www.prototron.ee *) Additional partners who want to be part of Estonia's next success stories.

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Investment focus

  • Industry: Software, Manufacturing, Internet of Things
  • Stage:Pre-Seed, Grant, Seed
  • Geography: Estonia, Finland, Germany

Investor stats

  • Total investments: 55
  • Round size: Seed $4k–$13k; Grant $3k–$27k; Pre-Seed $6k–$27k
  • Lead/follow: 75% lead, 25% follow

Portfolio highlights

  • Neurosalience — Neurosalience develops a tool for the early detection of dementia from structural MRI scans.
  • RAIKU — RAIKU is a cleantech startup that produces 100% natural packaging material that has also great looks and shock absorption - most importantly, it gives 15-20 times more volume to its raw material making it one of the most resource efficient material uses in the world with high margins. Both the production is and products are clean making no harm tonature. RAIKU has raised over 1.2mln€ in the pre-seed stage, built a team of over 10 people, its own IP and clients are already using its packaging material. This material will up-end the 1 trillion € packaging sector.
  • Jälle Technologies — Jälle Technologies create advanced recycling technologies that transform battery waste into high-value resources.
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Enterprise Estonia
VC Fund · Tallinn, Harjumaa, Estonia · 3 investments in Estonia Biotech startups

Enterprise Estonia (EAS), established in 2000, promotes business and regional development in Estonia. Enterprise Estonia is one of the largest institutions within the national support system for entrepreneurship, providing financial assistance, advisory, cooperation opportunities and training for entrepreneurs, research establishments, public andthird sector.

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Investment focus

  • Industry: Biotechnology, Software, Mobile Apps
  • Stage:Grant, Seed, Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 28
  • Round size: Seed $800k–$1.1M; Grant $16k–$2.1M; Pre-Seed $1.2M–$4.3M
  • Lead/follow: 54% lead, 46% follow

Portfolio highlights

  • Lifeyear — Digital-first heart care. At scale.
  • Rollo Robotics — Rollo Robotics develops autonomous monowheel security robots using gyroscopic stabilisation technology.
  • Jälle Technologies — Jälle Technologies create advanced recycling technologies that transform battery waste into high-value resources.
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Voima Ventures
VC Fund · Helsinki, Southern Finland, Finland · 2 investments in Estonia Biotech startups

Voima Ventures’ mission is to solve major global problems by combining science, entrepreneurship, and value adding capital. They shed light on the ideas and technology which require time and courage to build. Industry domains include bio and new materials, medical technologies and life sciences, imaging and optics, IoT and electronics, robotics,software & ICT and AI. In addition, Voima Ventures has invested in more than 30 deep tech startups, including companies like Solar Foods, Infinited Fiber Company, and Dispelix. Cornerstone investors are VTT Technical Research Centre of Finland and European Investment Fund (EIF), backed by Finnish private and institutional investors.

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Investment focus

  • Industry: Biotechnology, Health Care, Artificial Intelligence
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Finland, Sweden, Norway

Investor stats

  • Total investments: 59
  • Round size: Seed $1M–$5.5M; Pre-Seed $439k–$2.1M; Series A $3.8M–$18M
  • Lead/follow: 64% lead, 36% follow

Portfolio highlights

  • MVision AI — AI-powered solutions that automate repetitive tasks, enable efficient radiotherapy workflows, and promote consistency across clinical processes.
  • Quantrol Ox — Building Machine Learning Based Software for Quantum Control with a goal to maximise quantum computer uptime.
  • Adamant Health — Adamant Health’s unique technology to analyse Parkinson’s disease symptoms is based on over 15 years of academic research at the University of Eastern Finland. With the technology, clinicians have several days detailed visibility to the patient’s symptoms and is able to optimise the treatment accordingly. Pharma companies benefit from the objectiveand long-term RW data in their clinical and post market studies and can utilise it as complementary diagnostics tool for personalised medication.
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Nordic Foodtech VC
VC Fund · Helsinki, Southern Finland, Finland · 2 investments in Estonia Biotech startups

We are investing in #FutureFood. Nordic FoodTech VC is the first fund in the Nordics investing explicitly in the future of food

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Investment focus

  • Industry: Biotechnology, Life Science, Water
  • Stage:Seed, Series A
  • Geography: Finland, Sweden, Denmark

Investor stats

  • Total investments: 26
  • Round size: Seed $549k–$5.5M; Series A $7.4M–$18M
  • Lead/follow: 54% lead, 46% follow
  • Last fund: Likely still investing — raised $49M in 2021

Portfolio highlights

  • EvodiaBio — Mirroring nature with pioneering bioscience for natural flavors
  • Endless Food — Endless Food Co is a food innovation firm focusing on the junction of pleasure and sustainability. Endless Food Co was pulled together by a common idea that the transition to a greener and more egalitarian future food system will be driven by flavor, and having spent the last decade pioneering sustainable gastronomy
  • Happy Plant Protein — Revolutionize plant protein production with Happy Plant Protein's innovative technology, transforming local ingredients into high-quality, sustainable solutions for the food industry.
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SOSV
VC Fund · Princeton, New Jersey, United States · 1 investments in Estonia Biotech startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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AS AMALFI
Angel · 1 investments in Estonia Biotech startups

AS AMALFI

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
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Estonian Research Council
VC Fund · Tartu, Tartumaa, Estonia · 1 investments in Estonia Biotech startups

We support research and innovation in Estonia: provide research funding, R&D analysis, input for better policy-making and science communication activities.

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Investment focus

  • Industry: Biotechnology
  • Stage:Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: no public data

Portfolio highlights

  • MYCEEN — MYCEEN is a carbon-negative materials combining mushroom mycelium and industrial byproducts.
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Johanna Britt Berzin
Angel · Tartu, Tartumaa, Estonia · 1 investments in Estonia Biotech startups

Johanna Britt Berzin

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
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Robert Laud
Angel · 1 investments in Estonia Biotech startups

Robert Laud

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
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Ivo Remmelg
Angel · Tallinn, Harjumaa, Estonia · 1 investments in Estonia Biotech startups

Ivo Remmelg is a Venture Partner at Superhero Capital and the Founding Partner of NestCap. Ivo Remmelgs, President of the Estonian Business Angel Network.

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Investment focus

  • Industry: Mobile, Sports, FinTech
  • Stage:Seed, Angel, Pre-Seed
  • Geography: Estonia, Latvia, Norway

Investor stats

  • Total investments: 5
  • Lead/follow: 20% lead, 80% follow

Portfolio highlights

  • Sportlyzer — Sportlyzer is a player development and team management software for youth and amateur sports clubs. The platform connects coaches, managers, players and parents.
  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
  • Nordic Automation Systems — Full vertical LPWAN solution provider with flexible in-house R&D and production to enable fast roll out to the market.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Timo Rein
Angel · New York, New York, United States · 1 investments in Estonia Biotech startups

Timo Rein - Co-Founder @ Pipedrive

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Investment focus

  • Industry: Software, Recruiting, Human Resources
  • Stage:Seed, Angel, Convertible Note
  • Geography: Estonia, Finland, United Kingdom

Investor stats

  • Total investments: 10
  • Round size: Seed $280k–$1.2M
  • Lead/follow: 30% lead, 70% follow

Portfolio highlights

  • YuMuuv — YuMuuv is an employee wellness platform that uses science-based formulas to capture data and keeps track of physical activity & leaderboard.
  • Antegenes — Antegenes’ novel genetic tests assess a patient’s personal cancer risks, and include clinical recommendations for personalized cancer prevention. The tests are based on innovative polygenic risk score technology which helps to clarify a person’s genetic predispositions to cancer. It therefore allows for more accurate prevention and early detectionmeasures – crucial in the fight with cancer. The tests are currently being used to determine the genetic risk for four cancers: breast cancer, prostate cancer, colon cancer, and skin melanoma.
  • Bidrento — One powerful platform for your entire portfolio. The leading property and tenant management software. Scale your operations and maximize your profit with Bidrento. Try it already today!
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Domain Associates
VC Fund · San Diego, California, United States · 1 investments in Estonia Biotech startups

INVESTMENT ADVISORS TO THE FIRST VC FUND DEDICATED TO BIOTECH INVESTMENT MANAGER OF 9 SUBSEQUENT BIOTECH VC FUNDS

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series C, Series A
  • Geography: United States, Canada, Estonia

Investor stats

  • Total investments: 194
  • Round size: Series A $3.8M–$50M; Series B $10M–$60M; Series C $10M–$57M
  • Lead/follow: 16% lead, 84% follow
  • Last fund: May invest from a new fund soon — raised $164M in 2016

Portfolio highlights

  • Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
  • Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
  • Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.
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Johnson & Johnson Development Corporation
VC Fund · New Brunswick, New Jersey, United States · 1 investments in Estonia Biotech startups

JJDC, Inc. is the strategic venture capital arm of Johnson & Johnson Innovation. Learn more about our equity investment strategy.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series C, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 129
  • Round size: Series B $15M–$49M; Series C $12M–$40M
  • Lead/follow: 19% lead, 81% follow

Portfolio highlights

  • Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
  • Ronovo Surgical — Founded in 2019 and headquartered in Shanghai, Ronovo Surgical is founded by industry veterans from global leaders in surgical and industrial robotics, such as Intuitive Surgical, Johnson & Johnson, Medtronic and KUKA. Aiming to transform how surgery is performed in China, Ronovo is leveraging robust R&D capabilities and strategicpartnerships globally to accelerate the development of a broad portfolio of MIS and digital surgery solutions that exemplifies the core themes of simplicity, precision, and intelligence.
  • Osteal Therapeutics — Osteal Therapeutics is a privately-held, clinical-stage pharmaceutical company developing novel musculoskeletal therapeutics to treat orthopedic infections and their consequences.
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Hugues Flament
Angel · Brussels, Brussels Hoofdstedelijk Gewest, Belgium · 1 investments in Estonia Biotech startups

Hugues Flament

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
Show all investments...

Siim Sikkut
Angel · 1 investments in Estonia Biotech startups

Siim Sikkut

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Investment focus

  • Industry: Biotechnology
  • Stage:Pre-Seed
  • Geography: Estonia

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Gearbox Biosciences — A biotechnology company that licenses novel antibiotic-free recombinant protein production technology in E. coli.
Show all investments...

Crosslight Partners
VC Fund · 1 investments in Estonia Biotech startups

Crosslight Partners is a growth equity firm. The firm invests in the environment, healthcare, impact, and technology sectors across Europe.

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Investment focus

  • Industry: Biotechnology, B2B, Medical
  • Stage:Seed
  • Geography: Sweden, Estonia

Investor stats

  • Total investments: 2
  • Lead/follow: 50% lead, 50% follow

Portfolio highlights

  • Gelatex Technologies — Gelatex is a Techstars-backed materials technology company that invented the fastest technology for producing bio-based nanofibers on a large scale. It is a platform technology that enables faster and up to 100 cheaper nanofiber production for applications like 3D scaffolds for tissue engineering, cultured meat, bio-based filters, eco-friendlyleather-like textile, energy storage, wound care, and many more. The technology is patent-pending and the machinery fully functional. The company was founded in 2016 and until COVID-19 pandemic developed eco-friendly leather-like textile from gelatin nanofibers, using this nanofiber production technology as part of the process. COVID-19 was a trigger to understand the wider potential of the technology which then led to pivot.The company is based in Estonia and holding incorporated in UK (2019).
  • Sigrid Therapeutics — Sigrid Therapeutics is developing an ingested medical device for lowering blood sugar in prediabetics.
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Change Ventures
VC Fund · Tallinn, Harjumaa, Estonia · 1 investments in Estonia Biotech startups

We are a seed stage venture capital fund based in the Baltic states, backing ambitious Baltic founders anywhere in the world.

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Investment focus

  • Industry: Software, Information Technology, Apps
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Estonia, Latvia, Lithuania

Investor stats

  • Total investments: 63
  • Round size: Seed $500k–$4.5M; Pre-Seed $273k–$2.2M; Series A $1M–$33M
  • Lead/follow: 56% lead, 44% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Eurora — Eurora develops an e-commerce suite of customs compliance tools.
  • FanSifter — FanSifter is a fan data management platform that leverages machine learning to help rights holders in music, entertainment, and sports increase tickets, music, merch, experiences, and sponsorships sales.
  • RecruitLab — Teamdash's built-in recruitment, applicant tracking, and marketing features give you the focus you need to achieve the impossible. Here's how.
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Specialist VC
VC Fund · Tallinn, Harjumaa, Estonia · 1 investments in Estonia Biotech startups, 9 in the past 12 months

United Angels VC is an early stage venture capital fund based in Estonia.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Seed, Pre-Seed
  • Geography: Estonia, United Kingdom, Finland

Investor stats

  • Total investments: 64
  • Round size: Seed $587k–$6.5M; Pre-Seed $241k–$2.2M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: Likely still investing — raised $55M in 2022

Portfolio highlights

  • Sera — Sera's AI streamlines prospecting with tailored lists and enriched profiles, including accurate emails and metrics.
  • Copla — Simplify cybersecurity compliance with automated workflows, audits, and risk management. Our expert CISO team tailors solutions to your organization's needs.
  • CyberUpgrade — Simplify cybersecurity compliance with automated workflows, audits, and risk management. Our expert CISO team tailors solutions to your organization's needs.
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Peep Vain
Angel · 1 investments in Estonia Biotech startups

Peep Vain is the Private Investor at Vain and Partners. He attended Bentley University.

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Investment focus

  • Industry: Software, Genetics, Recruiting
  • Stage:Seed, Angel
  • Geography: Estonia

Investor stats

  • Total investments: 5
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Antegenes — Antegenes’ novel genetic tests assess a patient’s personal cancer risks, and include clinical recommendations for personalized cancer prevention. The tests are based on innovative polygenic risk score technology which helps to clarify a person’s genetic predispositions to cancer. It therefore allows for more accurate prevention and early detectionmeasures – crucial in the fight with cancer. The tests are currently being used to determine the genetic risk for four cancers: breast cancer, prostate cancer, colon cancer, and skin melanoma.
  • Bisly — Bisly Scalable Building Automation reduces the overhead for building professionals and makes energy saving easy and affordable.
  • Bidrento — One powerful platform for your entire portfolio. The leading property and tenant management software. Scale your operations and maximize your profit with Bidrento. Try it already today!
Show all investments...

Grid.vc
VC Fund · Helsinki, Southern Finland, Finland · 1 investments in Estonia Biotech startups

Grid.vc is the first investor in superb teams disrupting the energy business.

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Investment focus

  • Industry: Energy, Renewable Energy, SaaS
  • Stage:Seed, Pre-Seed
  • Geography: Finland, Estonia

Investor stats

  • Total investments: 6
  • Round size: Seed $20k–$6.3M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Bioreactor — Bioreactor is a revolutionary technology that converts bio waste into clean energy through biomass gasification. It's a sustainable, efficient and cost-effective solution that addresses energy poverty, energy security and climate change. With the use of the latest technology in computational fluid dynamics, cloud-optimized digital twin anddeep learning algorithms, the Bioreactor can optimize its performance in real-time over a wide range of fuels and operating conditions. The Bioreactor is a game changer in the energy industry, it can reduce greenhouse gas emissions, drastically lower energy costs, and help to alleviate energy poverty on a national scale.
  • Safegrid — Smarter sensors for a smarter grid
  • Vensum Power — Revolutionizing power conversion. More power in same package, less energy waste and low maintenance.
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