Top 25 Biotech Startup Investors in Estonia (November 2026)

Portfolio highlights

• Solaride — Solaride is a bunch of progressive pioneers of the future who are building Estonia's first solar car to face the ultimate challenge to prove how successfully students can create innovation.
• RAIKU — RAIKU is a cleantech startup that produces 100% natural packaging material that has also great looks and shock absorption - most importantly, it gives 15-20 times more volume to its raw material making it one of the most resource efficient material uses in the world with high margins. Both the production is and products are clean making no harm tonature. RAIKU has raised over 1.2mln€ in the pre-seed stage, built a team of over 10 people, its own IP and clients are already using its packaging material. This material will up-end the 1 trillion € packaging sector.
• Jälle Technologies — Jälle Technologies create advanced recycling technologies that transform battery waste into high-value resources.

Portfolio highlights

• ÄIO — Innovative food technologies to replace palm oil, coconut oil and animal fats with sustainable and healthier alternatives.
• Lifeyear — Digital-first heart care. At scale.
• Rollo Robotics — 1ROLLO is the world's first commercial autonomous one-wheeled security robot. Making security services 10x cheaper, smarter, and more energy-efficient.

Portfolio highlights

• OlsAro — OlsAro produces salt-tolerant crops.
• MÖ Foods — MÖ Kaurajogu is domestic, completely herbal and above all delicious. All our products are manufactured in Central Ostrobothnia, Lohtaja.
• AquaNab Solutions — AquaNab is a biotechnology startup developing precision immunotherapies for aquaculture. The company's core platform uses alpaca-derived nanoantibodies (called AquaNabs) formulated directly into fish feed. This approach allows the therapeutic molecules to cross the fish's intestinal barrier and target pathogens from the bloodstream.

Portfolio highlights

• FluoSphera — Fluosphera better predicts the effects of molecules through animal-free microphysiological systems, helping you to discover more efficient drugs with less adverse side effects.
• Giraffe Bio — Giraffe Bio uses AI and biomolecules to optimize metal extraction, increase yield, and reduce environmental impact. Revolutionizing sustainable mining technology.
• Transition Metal Solutions — Transition harnesses wild microbial communities to recover copper and other critical metals from low-grade mining resources.

Portfolio highlights

• Halla — Halla Intelligence is a digital solution that leverages over 100 billion shopper and product data points to recommend and promote what grocery items.
• Verdex Technologies — Verdex Technologies is an advanced materials platform technology that uses nanofibers to disrupt industries. Verdex doesn't just compete, it innovates and disrupts.
• Samphire Neuroscience — Samphire Neuroscience builds clinically validated neurotechnology to support women across their lives. Our wearable devices, Nettle™ and Lutea™, are built on the same underlying brain-stimulation technology, targeting neural pathways involved in pain, mood, stress, and sleep regulation. - Lutea™ is available globally as a wellness device. Itstimulates the same regions of the brain to support stress regulation, sleep, and recovery - key drivers of readiness and long-term performance - allowing athletes and teams to move beyond wellbeing education alone to practical, evidence-based intervention. - Nettle™ is a CE-marked (EU and UK regulated), drug- and hormone-free device that has been clinically shown to improve pain, mood, functionality, and the ability to train during the menstrual cycle, with measurable benefits after one month of use - supporting athletes to maintain training intensity and movement quality during their period. - The Samphire App is the platform controlling all Samphire hardware products with the use of CycleSync™ AI technology: the only one of its kind to support personalized neurotechnology use for women.

Portfolio highlights

• Reduciner — Reduciner's vision to turn industrial CO₂ emissions from a liability into a valuable resource. Its technology converts captured carbon dioxide and biochar into valuable feedstocks such as carbon monoxide and activated carbon, enabling circular carbon use in emissions-intensive industries. Reduciner combines strong scientific expertise withindustrial applicability across sectors such as cement, steel, and chemicals. Its electricity-driven process allows industries to reduce emissions without major changes to existing infrastructure, offering a resilient and cost-competitive way to reduce carbon dependency while creating new value from CO₂ emissions.
• TheStorage — Flexible industrial heat electrification and scalable energy storage. TheStorage offers cost efficient, sustainable grid scale energy storage that can discharge heat, steam or CHP.
• Aventix — Aventix is a bioanalytics/life-science instrumentation company that develops sensor-based laboratory tools.

Portfolio highlights

• Efenco — Efenco is a deep-tech startup developing patented clean energy conversion technologies, that increase the combustion efficiency of natural gas and hydrogen by unprecedented 18%
• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics
• Nordic Automation Systems — Nordic Automation Systems (NAS) is an industrial automation company. We believe in the world with precise data and less tedious repetitive manual tasks. We create sensor technologies, data analysis and monitoring solutions.LoRa® technology enables us to provide end-to-end LoRaWAN™ - smart metering, smart monitoring, smart city and industrialIoT applications. NAS has about 25 employees in it's Norwegian and Estonian offices and customers in every continent.

Portfolio highlights

• Corthera —
• Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
• NovaDigm Therapeutics — NovaDigm blends modern telemedicine with a focus on longevity and wellness, while continuing to report on cutting-edge advancements in biotechnology and therapeutics.

Portfolio highlights

• GaltTec — GaltTec focuses on developing and marketing microtubular solid oxide fuel cells. GaltTec specializes in drones, off-grid equipment, IoT, portable devices, and space equipment. GaltTec was founded in 2022 and was headquartered in Tartu, Estonia.
• Bisly — Bisly is an Estonian startup developing intelligent building solutions.
• Nanordica Medical — Nanordica Medical develops novel nanoparticle-based antibacterial wound care products.

Portfolio highlights

• YuMuuv — Employee wellness app for organizing any type of workplace wellness challenge. Proven platform to increase happiness and engagement at work.
• Antegenes — Antegenes’ novel genetic tests assess a patient’s personal cancer risks, and include clinical recommendations for personalized cancer prevention. The tests are based on innovative polygenic risk score technology which helps to clarify a person’s genetic predispositions to cancer. It therefore allows for more accurate prevention and early detectionmeasures – crucial in the fight with cancer. The tests are currently being used to determine the genetic risk for four cancers: breast cancer, prostate cancer, colon cancer, and skin melanoma.
• Bidrento — One powerful platform for your entire portfolio. The leading property and tenant management software. Scale your operations and maximize your profit with Bidrento. Try it already today!

Portfolio highlights

• Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
• Ronovo Surgical — Ronovo Surgical is an emerging medtech company focused on innovating minimally invasive (MIS) and digital surgery.
• Osteal Therapeutics — Osteal Therapeutics is a privately-held, clinical-stage pharmaceutical company developing novel musculoskeletal therapeutics to treat orthopedic infections and their consequences.

Portfolio highlights

• Impress — Impress – is European leading digital orthodontic DSO of new generationWe have a defensible model with the personal touch of an in-house orthodontist, true clinical expertise, and engaging directly with consumersImpress was founded in 2019 in Barcelona with the idea of combining the best of orthodontic tradition with the most innovativetechnology in the sector. From the very beginning the vision of the Impress founders was to introduce a different business model with a strong focus on medical experience and digitalization. The company is transforming the oral healthcare industry by developing its own chain of orthodontic clinics, which are characterized by their disruptive design and modern patient experience. The founders decided to build a medical company with the personal touch of in-house orthodontists, face-to-face care, and unique clinical expertise, where the proper implementation of business processes and digitalization are at the core.In less than 2 years, Impress has managed to position itself as the European leader in the orthodontic sector, has treated more than 22.000 smiles and already has a presence in more than 80 European cities. Its innovation and quality have earned it recognition from Sifted as one of the fastest growing HealthTech companies in Europe in 2020.
• Santander Brasil — Banco Santander in Brazil, its largest division in Latin America and one of the world's most important, accounting for 50%.
• Dandara Solar Power SAE — Dandara Solar Power SAE is a special purpose vehicle, established to develop a major renewable energy and storage project in Upper Egypt. The entity oversees the development and operational construction of a 500 MW solar PV plant integrated with a 100 MWh Battery Energy Storage System. All electricity generated by the company is bound to be sold to the industrial manufacturer Misr Aluminum Company under a long term, take or pay power purchase agreement.

Portfolio highlights

• UP Catalyst — UP Catalyst produces sustainable carbon nanomaterials and graphite for the green energy storage industry.
• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• BirdyChat — One chat for your team, people outside your company, and your agents. Free, built, and hosted in the EU.
• Giraffe360 — Real estate camera and AI software that turns one property capture into HDR photos, floor plans, 360 virtual tours, videos and property websites.
• Saltz — Premium ingredients for your menu with no hidden delivery fees or markups.

Portfolio highlights

• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• Patchstack — Keep your WordPress sites and JavaScript apps safe from vulnerable plugins, themes & npm packages. Protect sites with virtual patching.
• Nora AI — Nora AI offers a course for antiviral drug discovery by focusing on host cells. Nora provides scientists with profound insights into disease mechanisms and spotlights high-potential drug candidates.
• DriveX Technologies — Decrease your average claim size with AI vehicle inspection tool for CASCO pre-checks and windshield claims.

Portfolio highlights

• Copla — Simplify cybersecurity compliance with automated workflows, audits, and risk management. Our expert CISO team tailors solutions to your organization's needs.
• CyberUpgrade — Simplify cybersecurity compliance with automated workflows, audits, and risk management. Our expert CISO team tailors solutions to your organization's needs.
• Nanordica Medical — Nanordica Medical develops novel nanoparticle-based antibacterial wound care products.

Portfolio highlights

• Bioreactor — Bioreactor is a revolutionary technology that converts bio waste into clean energy through biomass gasification. It's a sustainable, efficient and cost-effective solution that addresses energy poverty, energy security and climate change. With the use of the latest technology in computational fluid dynamics, cloud-optimized digital twin anddeep learning algorithms, the Bioreactor can optimize its performance in real-time over a wide range of fuels and operating conditions. The Bioreactor is a game changer in the energy industry, it can reduce greenhouse gas emissions, drastically lower energy costs, and help to alleviate energy poverty on a national scale.
• Safegrid — Smarter sensors for a smarter grid
• Vensum Power — Revolutionizing power conversion. More power in same package, less energy waste and low maintenance.

Portfolio highlights

• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• Antegenes — Antegenes’ novel genetic tests assess a patient’s personal cancer risks, and include clinical recommendations for personalized cancer prevention. The tests are based on innovative polygenic risk score technology which helps to clarify a person’s genetic predispositions to cancer. It therefore allows for more accurate prevention and early detectionmeasures – crucial in the fight with cancer. The tests are currently being used to determine the genetic risk for four cancers: breast cancer, prostate cancer, colon cancer, and skin melanoma.

Portfolio highlights

• Gearbox Biosciences — Gearbox Biosciences provides stable template plasmids for long poly(A) mRNA therapeutics

Portfolio highlights

• Antegenes — Antegenes’ novel genetic tests assess a patient’s personal cancer risks, and include clinical recommendations for personalized cancer prevention. The tests are based on innovative polygenic risk score technology which helps to clarify a person’s genetic predispositions to cancer. It therefore allows for more accurate prevention and early detectionmeasures – crucial in the fight with cancer. The tests are currently being used to determine the genetic risk for four cancers: breast cancer, prostate cancer, colon cancer, and skin melanoma.
• Bisly — Bisly is an Estonian startup developing intelligent building solutions.
• Bidrento — One powerful platform for your entire portfolio. The leading property and tenant management software. Scale your operations and maximize your profit with Bidrento. Try it already today!

Portfolio highlights

• MYCEEN — MYCEEN is a carbon-negative materials combining mushroom mycelium and industrial byproducts.
• KappaZeta — Kappazeta's AI-driven satellite insights help governments and businesses make fact-baseddecisions and save time on analyzing vast amounts of data globally.