Top 45 Enterprise Software Startup Investors in Italy (August 2026)

Portfolio highlights

• Evja — Evja supports growers in optimizing the management and monitoring of irrigation, nutrition and protection of their crops through the use of OPI, the most advanced system for precision agriculture .
• Mopso — Discover Mopso's anti money laundering detection system. Visit our website and try a 30 minutes free demo with one of our experts.
• ALLSIDES — Covision Media specializes in creating high-quality, relightable 3D models using their industrial 3D scanners. These scanners capture detailed surface information and PBR textures, and are designed for easy integration into virtual environments.

Portfolio highlights

• Klaro — Klaro is an AI platform that assists small businesses with credit and improves cash flow management.
• Talentware — Talentware is the platform that lets you manage your company and people by putting skills first: boosting engagement, talent retention, and productivity.
• Circular Materials — Scopri Circular Materials: immagina una tecnologia che tratta le acque reflue e, allo stesso tempo, recupera metalli preziosi.

Portfolio highlights

• Banxware — Banxware provides the technology and the funds for business financing of any kind: fully embedded in your platform or as an affiliate solution - all managed by Banxware
• Retina — Retina si occupa di realizzare infrastrutture nel Mezzogiorno per la produzione di biometano dalla conversione dei reflui zootecnici.
• Polo Strategico Nazionale — Scopri Polo Strategico Nazionale: il cloud sovrano per la gestione dei dati e servizi della Pubblica Amministrazione italiana.

Portfolio highlights

• Gility — Gility is a digital learning platform that collaborates with business schools and training institutions for an effective training offer. Established in 2022, it was supported by CDP Venture Capital and BPER Banca.
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.
• Valvitalia SpA. — VALVITALIA is a leading group in the field of design, production, and overall supply of equipment and components intended for the petroleum, water, natural gas industries, and petrochemical industry as well as electrical power stations. The group works mainly with valves (core product), actuators, pipe fittings, flanges and systems for measuring,filtering, and regulating fluids and gases and with FireFighting systems. VALVITALIA was set up with the precise objective of becoming the leading Italian group able to offer such a wide range of products and to compete with the large American multinationals that have always dominated this field. This young company has extensive experience in the sector, thanks to its professional management and historical brands in the valve world that have been taken on by the Group, including: ROTOR, DELTA V.E., THEVIGNOT, VANADOUR, VITAS, TORMENE T.G.T. and TECNOFORGE. VALVITALIA has always included safety and respect for the environment and its employees among its priorities.

Portfolio highlights

• ORiS — ORiS (Orbital Recharge in Space) develops laser-based wireless power transmission to extend the autonomy of satellites, drones, and lunar habitats.
• Doctorsa — Doctorsa is a digital marketplace offering travelers instant access to urgent care online for common conditions, starting at just €20.
• Always Friday — Piattaforma AI per eventi aziendali in Italia: 2.500+ location, team building, retreat e eventi su misura con proposte qualificate e un event manager dedicato per ogni progetto.

Portfolio highlights

• Cleafy — A new era for online fraud management: Cleafy combines in real-time all the most advanced fraud detection technologies in one fraud management solution.
• Beelzebub — A secure low code deception runtime framework, leveraging AI for System Virtualization.
• Seltz — The Web Knowledge Layer for AI Agents.

Portfolio highlights

• THRON — La piattaforma che raccoglie, cataloga, connette e distribuisce il patrimonio di contenuti e dati di prodotto della tua azienda.

Portfolio highlights

• CiaoDott — Automatizza le telefonate, prenotazioni e FAQ del tuo studio medico con CiaoDott, l'assistente vocale AI disponibile 24/7. Provalo gratis.
• Octostar — Octostar is the AI-powered investigative intelligence platform for law enforcement, national security, and financial institutions. Connect the dots and discover the facts across petabytes of data.
• Mirai Robotics — Autonomy and intelligence for the seas. We're building software-defined autonomous systems and AI platforms that unify vessels, sensing, and command at sea.

Portfolio highlights

• Spoki — Spoki is the WhatsApp Marketing platform that boosts sales and engagement. Automated campaigns, AI-powered customer service, 100+ integrations. Start free.
• Kleecks — Kleecks is an innovative SaaS platform that optimises performance marketing activities, improves website health and speed in real-time, and has a significant impact on businesses by increasing revenues, lowering costs, and accelerating time-to-market
• Connected-Stories — Connected-Stories is the Multi agent Ai system that powers generative AI for marketing, creative automation, and personalized content at scale.

Portfolio highlights

• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company

Portfolio highlights

• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company

Portfolio highlights

• Alomana — Autonomous systems for enterprise

Portfolio highlights

• Ventive Group — Ventive Group is a venture capitalist that provides personalized advice to support innovative startups and SMEs.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.
• Tethys Robotics — Tethys Robotics develops AI-powered application oriented robotics system that enables professionals in carrying underwater search & recovery to inspection & surveillance.

Portfolio highlights

• Warren — Enabling wealth, Boosting welfare
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.
• Sightera Biosciences — Revolutionizing drug discovery through AI-powered analysis of patient-derived models for breakthrough therapeutics in cancer and regenerative medicine.

Portfolio highlights

• Gyala — Gyala protegge le infrastrutture IT, OT e IoT con Agger: detection e reaction automatiche H24, AI di derivazione militare e tecnologia 100% italiana.
• Hibot — Hibot offers robotic platforms, and related hardware and software solutions. The company offers robots for hazardous operations as well as for maintenance and inspection of infrastructure, search, and rescue missions. The company was founded in 2004 and is based in Tokyo, Japan.
• Hypermeteo — Hypermeteo develops and provides high-quality, high-resolution weather and climate data through a powerful API-based platform. By analyzing observations on detailed territorial grids, the company provides historical, real-time, nowcasting and forecasting data, risk assessments, early warning systems, and future climate projections that supportinformed decision-making. These insights enable companies and organizations to integrate climate intelligence into their business planning, enhance operational capabilities, manage climate-related risks, and adapt to climate change, ultimately helping to reduce climate-driven impacts and losses across sectors such as energy, insurance, infrastructure, finance, agriculture, and urban planning.

Portfolio highlights

• Seltz — The Web Knowledge Layer for AI Agents.
• compri — AI Agents that automate sourcing, supplier management and procurement operations for manufacturing companies. Your new team colleagues.
• Pillar — Sites, finance and administration in one intelligent platform.

Portfolio highlights

• THRON — La piattaforma che raccoglie, cataloga, connette e distribuisce il patrimonio di contenuti e dati di prodotto della tua azienda.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — BigProfiles is an Artificial Intelligence Platform designed for Utilities, Telcos, Banks, Insurance companies and Retails.Large companies such as Teleperformance, Eni, Unicef already have already successfully subscribed to our services.BigProfiles is the No-Code Artificial Intelligence Platform for sales and antichurn that predicts thelikelihood to purchase and churn of each customer in a CRM, before proceeding to contact him in a sales or retention campaign.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• Alomana — Autonomous systems for enterprise
• PteroDynamics — PteroDynamics in an aircraft manufacturer that builds ultra-long-range VTOL aircraft based on its Transwing aircraft design with folding wings
• Purple Style Labs — Purple Style Labs is an IIT-Bombay graduate and ex-banker with Deutsche. It aspires to be the biggest fashion house of India managing multiple designer brands in the premium, luxury as well as affordable retail segment.

Portfolio highlights

• Bricks.sh — The fastest way to build and manage your Supabase database. One-click admin panel with powerful features for teams.
• TaDa — TaDa is an energy efficiency company that provides disaggregate energy consumption analytics for users to manage energy usage.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• CiaoDott — Automatizza le telefonate, prenotazioni e FAQ del tuo studio medico con CiaoDott, l'assistente vocale AI disponibile 24/7. Provalo gratis.
• Quantum Bridge — Quantum Bridge is a pioneer in Distributed Symmetric Key Exchange (DSKE) technology. It offers quantum-safe cybersecurity products and services. Quantum-safe product and services, Quantum-safe roadmap and quantum-safe solutions implementation.

Portfolio highlights

• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company
• Lumio Technologies — Lumio app is the free and smart way for people to track, save and invest every penny without needing a spreadsheet.
• MV.Health — MysteryVibe offers the most advanced & award winning smart sex toys for men, women & couples that elevates their sexual health and wellbeing.

Portfolio highlights

• Nomerra — The AI Coworker in Private Market Operations
• LimX Dynamics — Zhuji Dynamics is a general-purpose footed robot company that focuses on the R&D and manufacturing of sports intelligence and footed robots
• Zhuji Dynamics — Zhuji Dynamics is a general-purpose footed robot company that focuses on the R&D and manufacturing of sports intelligence and footed robots

Portfolio highlights

• Akeron Srl — Akeron Srl offers services such as implementation and training, managed services, support and houselab.

Portfolio highlights

• TAC S.r.l. — Entra nel futuro del networking con Smart Card personalizzate. Tecnologia NFC e QR. Porta il tuo Business con te.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• Webidoo — Scopri il Webidoo AI Operating System per il Business, il layer operativo che potenzia le imprese e guida l'innovazione tecnologica nel B2B.
• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company
• UpSurgeOn — The UpSurgeOn Academy is a hi-tech sequence of virtual and physical technologies designed to support Mental and Manual training and empower cognitive and psychomotor skills of any surgeon.

Portfolio highlights

• TextYess — Increase your eCommerce Retention with a Frictionless Experience.
• Tot — Tot is a business banking platform for SMEs.
• compri — AI Agents that automate sourcing, supplier management and procurement operations for manufacturing companies. Your new team colleagues.

Portfolio highlights

• THRON — La piattaforma che raccoglie, cataloga, connette e distribuisce il patrimonio di contenuti e dati di prodotto della tua azienda.

Portfolio highlights

• Webidoo — Scopri il Webidoo AI Operating System per il Business, il layer operativo che potenzia le imprese e guida l'innovazione tecnologica nel B2B.
• Satispay — Satispay: l'app per i pagamenti di tutti i giorni. Scopri i servizi per pagare e risparmiare, gli strumenti per il Business e i prodotti Welfare per aziende.
• SonoBee Ultrasound — As Malaysia's most trusted ultrasound and health screening centre, we combine expert radiologists with advanced imaging for precise results. Experience care you can rely on. Book your appointment.

Portfolio highlights

• Kampaay — The digital platform for organizing corporate events, in person, virtual or hybrid, in just a few clicks!
• Serenis Health — Serenis Health provides video-based psychotherapy, coaching, and psychological support courses. It believes that the internet is critical to increasing access to mental health care. It makes use of data and digital tools to improve the efficacy of therapies. But, unlike other platforms, it is also a medical center, which means it is responsible forcourse quality and must meet the same standards as any polyclinic.
• AutoConnexa — Scopri AutoConnexa, l'assicurazione online per la tua auto che premia lo stile di guida. Con Drive Connexa, meglio guidi e meno paghi.

Portfolio highlights

• qomodo — Qomodo: La piattaforma BNPL innovativa. Rate a tasso zero, approvazioni veloci, transazioni sicure. Rivoluzionaria nell'acquisto per aziende e consumatori.
• QisstPay — QisstPay makes eCommerce easier by allowing you to better convert customers with a seamless checkout experience. You can add and test any payment method; payment processors, BNPL, Crypto, Financing, and more.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• Glaut — Glaut is the AI-native platform for market research. Use AI-moderated interviews (AIMI) to collect qualitative insights at scale, with multilingual support, fraud prevention, and real-time analysis.
• Volta — Volta is a developer of software-as-a-service platform focusing on B2B commerce.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• AGORA — Agora World discover and create honest beauty content.
• ZAGO Milano — La tua skincare e skin-prep Made in Italy con Amore!
• Applied Computing — Applied Computing delivers industrial AI to the energy industry including oil and gas, refineries, and petrochemical plants, helping critical operations harness 100% of their data and optimise in real time for safer, faster, higher-performing decisions

Portfolio highlights

• Remuner — Say goodbye to spreadsheets. Remuner is the sales compensation software that automate your commissions and drive performance.
• Niino.it — Niino is a digital healthcare logistics platform provide easy, rapid, and transparent access to non-urgent medical rides, transforming a historically fragmented and analog sector into an automated, digital-first experience.
• CommerceClarity — AI-native platform powering the next generation of e-commerce through intelligent agents.

Portfolio highlights

• Ca' D'ORO — Ca' D'ORO is an industrial company that focuses on the natural stone sector. The company's main production of natural stone blocks and semi-finished products such as marble, granite, onyx, travertine, and quartzite are the main natural products that the company transforms and markets all over the world.
• BMG Pharma — BMG Pharma S.p.A.is an Italian pharmaceutical company and the first company in the world to develop products based on modified Sodium Hyaluronate, a patent protected technology which they brand as hyaluromimethic technology. BMG headquarters is currently located in Milan, Italy. It is a business to business company and its business model is basedon signing distribution and licensing agreements with companies worldwide to sell and distribute its products. In 2018, BMG acquired another Italian company, Sigea S.r.l, with expertise in the development of targeted functional ingredients, specifically focused on modified Hyaluronic Acid (Sodium Hyaluronate).
• Poetronicart — Poetronicart is a technological platform which enhance and create opportunity for artistic work and projects.

Portfolio highlights

• GHOSTDRIVE — The Ghostdrive leverages the decentralized nature of P2P networks (IPFS, and Filecoin) to provide unlimited data uploads. Unlike traditional centralized systems, where storage capacity is finite, P2P networks can dynamically expand their storage capabilities as more users join the network.
• Flanksource — Mission Control is an open-source, Kubernetes inspired internal developer portal that helps teams improve developer productivity and operational resilience.
• SEO Site Checkup — SEO Site Checkup offers webmasters, small business owners, and SEO agencies with SEO tools, software, and articles. It offers users with analysis and monitoring tools to analyze SEO issues of websites, to generate white-label SEO reports, to receive notifications on SEO score changes, and to understand their competitors’ SEO profiles.SEO SiteCheckup is operated from New York, United States.

Portfolio highlights

• Newcleo — newcleo is the clean and safe nuclear technology company. Privately funded and headquartered in London, UK, newcleo was launched in 2021 to be a disruptor in the field of nuclear energy. Its mission is to generate safe, clean and inexhaustible energy for the world, through a radically innovative combination of existing, accessible technologies.newcleo is building the next generation system with the goals to: (1) eliminate the need for geological repositories by using a fast neutron flux avoiding production of long life radioactive elements; (2) develop an Accelerator Driven System (ADS), based on the intrinsically safe coupling of a particle accelerator and a sub-critical reactor; (3) accelerate the development of new fuel cycles, including thorium, that provide economic, clean, safe and inexhaustible energy from nuclei and the opportunity to burn the long-lived nuclear waste produced by the old generation of nuclear reactors.With visionary co-founders, newcleo brings together a team of engineers with deep knowledge of nuclear energy with younger recruits with a fresh mindset, working to design an innovative micro Lead Fast Reactor with significant commercial applications, for example in shipping. newcleo wants to be the first step toward the evolution of its industry to become fully respectful of people and the environment. To develop a new, sustainable, and completely safe way of generating nuclear energy that will lead humanity to zero emissions, and to the mitigation of global warming.
• Kampaay — The digital platform for organizing corporate events, in person, virtual or hybrid, in just a few clicks!
• Underscore District — Underscore District unlocks the potential of Made in Italy fashion brands through the power of technology and data analytics.

Portfolio highlights

• Logiq.ai — Logiq is a real-time log aggregation and analysis platform for monitoring and logs. It was founded in 2019 and is based in San Jose, California.
• Kayna — Enhance your SaaS platform's value by integrating Kayna's insurance solutions. Drive additional revenue and offer more to your users with every policy sold.
• StrainX Bioworks —

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Therapeutics develops innovative targeted cancer therapy solutions using its proprietary YntraDose technology for nuclear medicine.

Portfolio highlights

• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company

Portfolio highlights

• SylloTips — SylloTips is an all-in-one knowledge sharing platform that leverages artificial intelligence to optimize the circulation of skills and knowledge among all employees in a company

Portfolio highlights

• Kampaay — The digital platform for organizing corporate events, in person, virtual or hybrid, in just a few clicks!

Portfolio highlights

• BKN301 — Scopri tutti i servizi dedicati a privati, aziende ed esercenti. Accedi all'area riservata.
• Subbyx — Subbyx provides long-term subscriptions for technology products and small home appliances.
• DRONUS — Dronus provides inspection, safety, and smart city capabilities from an innovative, minimally invasive base that guarantees the drone's flight stability and safety during take-off and landing, even in difficult climatic conditions.