Top 25 Enterprise Software Startup Investors in Italy in May 2026

Portfolio highlights

• ALBA Robot — Through our micro mobility platform we add autonomy and artificial intelligence to transform passengers transportation.
• RARA Factory — RARA Factory is a company that provides research and development of sustainable materials utilizing physics-based artificial intelligence.
• Proxima Fusion — We are a European fusion energy startup pursuing the clearest path to grid deployment.

Portfolio highlights

• Noiet — Noiet is a biotechnology firm whose mission is to develop clean, natural, and fermented proteins that serve as multifunctional alternatives.
• Feralpi Group — Feralpi Group is a steel manufacturer that specializes in the production of construction steels, responsibility, safety, and innovation.
• E4 Computer Engineering — E4 Computer Engineering stands out for its tireless pursuit of the most cutting edge proposals in the IT sector.

Portfolio highlights

• Temelion — Temelion is an AI copilot to assist building engineers during their pre-construction workflows so they can deliver high quality projects on time, faster while preserving their margins.
• iNGage — iNGage is a manufacturer of high-performance inertial MEMS navigation sensors for high-volume autonomous mobility markets
• Innoviz Technologies — A leading supplier of high-performance, automotive-grade LiDAR sensor platforms.

Portfolio highlights

• THRON — Siamo THRON. Quelli della piattaforma unica per governare insieme asset digitali e dati di prodotto, distribuendoli su tutti i tuoi canali di comunicazione.

Portfolio highlights

• Plino — Plino is the SMEs FP&A co-pilot, integrating your company data and making it faster and easier to analyse them, empowering entrepreneurs in taking successful informed decisions. On one side it collects, organizes and analyses data from different company’s data sources such as invoices, bank accounts, MES, ERP, WMS, industry 4.0 data, andcompany documents (contracts, technical data sheets). On the other, it provides a user-friendly chat where the user (either the entrepreneur, the CFO, or the accountant) can type questions and receive fast, precise and insightful answers on the company’s revenues, costs, clients, products, and production process. Its mission is to empower SME’s managers to take better informed strategic decisions to lead the company to scale toward success by overcoming market uncertainty.
• Cyberwave — Transform your industry with AI-defined robotics. Frictionless automation that makes advanced robotics accessible to manufacturers of all sizes.
• The Bland Company — The Bland Company is a biotechnology and food startup headquartered in London, focused on developing simple, transformative ingredients. The company operates within the biotechnology research industry and has a small team, with a company size estimated between 2–10 employees. Its official website, theblandcompany.co, indicates it is preparing tolaunch products or services, as the site currently features a "Coming Soon" message along with a newsletter subscription option.

Portfolio highlights

• Lexroom.ai — Lexroom.ai allows lawyers to complete hours of legal research in seconds.Legal professionals spend up to 50% of their time in repetitive, low value-adding tasks. That’s why we’re building Lexroom.ai, a product that allows lawyers to complete hours of research in seconds, so they can focus on what really matters.Lexroom.ai perfectly integrateswith lawyers' daily workflow and enables them to speed up time-consuming legal research tasks while increasing output quality, so that they can focus more on value-adding activities.Lexroom.ai is building a bridge between advanced artificial intelligence technologies and legal professionals, through a product specifically tailored to their needs.
• Epiminds — Epiminds develops multi-agent AI systems to run marketing end-to-end.
• Handhold — Handhold is an AI platform that creates multimodal agents to automate the sales and onboarding process for inbound leads.

Portfolio highlights

• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• Bricks.sh — The fastest way to build and manage your Supabase database. One-click admin panel with powerful features for teams.
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• qomodo — Qomodo: La piattaforma BNPL innovativa. Rate a tasso zero, approvazioni veloci, transazioni sicure. Rivoluzionaria nell'acquisto per aziende e consumatori.
• QisstPay — QisstPay makes eCommerce easier by allowing you to better convert customers with a seamless checkout experience. You can add and test any payment method; payment processors, BNPL, Crypto, Financing, and more.
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.
• Connectome Health — Connectome is a cognitive intelligence platform that measures and understands how the brain changes over time using transparent, science-backed data people and organisations can trust.
• Multiverse Computing — World leaders in quantum computing for the financial industry. The first quantum & quantum-inspired toolbox for finance.

Portfolio highlights

• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• Glaut — Glaut is the AI-native platform for market research. Use AI-moderated interviews (AIMI) to collect qualitative insights at scale, with multilingual support, fraud prevention, and real-time analysis.
• qomodo — Qomodo: La piattaforma BNPL innovativa. Rate a tasso zero, approvazioni veloci, transazioni sicure. Rivoluzionaria nell'acquisto per aziende e consumatori.
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• ReportAId — ReportAId is an AI-powered software that breathes life into medical reports to make healthcare more organized, customized, and accessible.
• Sava Technology — SAVA is reinventing health monitoring with a novel biosensing platform enabling real-time, affordable, and painless molecular monitoring.
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• Bricks.sh — The fastest way to build and manage your Supabase database. One-click admin panel with powerful features for teams.
• compri — Automate all your Procurement activities with AI
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• TAC S.r.l. — Entra nel futuro del networking con Smart Card personalizzate. Tecnologia NFC e QR. Porta il tuo Business con te.
• CommerceClarity — CommerceClarity offers AI-powered catalogue optimization solutions that turn catalogue operations into a competitive advantage.

Portfolio highlights

• Webidoo — We provide the digital tools and advanced that big businesses use, but built and designed so they can be easily utilized by local independent business owners. webidoo is dedicated to partnering with local businesses. We’re here to give the solutions you need to connect with customers, wherever they may be. Our clients include businesses of everytype: restaurants, attorneys, builders, doctors, delicatessens, electricians and many others. We can provide solutions that allow companies to connect with their customers, real and potential, like never before. We’re all about supporting local businesses. And we feel good about that.
• Satispay — Satispay: l'app per i pagamenti di tutti i giorni. Scopri i servizi per pagare e risparmiare, gli strumenti per il Business e i prodotti Welfare per aziende.
• SonoBee Ultrasound — As Malaysia's most trusted ultrasound and health screening centre, we combine expert radiologists with advanced imaging for precise results. Experience care you can rely on. Book your appointment.

Portfolio highlights

• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Therapeutics develops innovative targeted cancer therapy solutions using its proprietary YntraDose technology for nuclear medicine.

Portfolio highlights

• AGORA — Agora World discover and create honest beauty content.
• ZAGO Milano — La tua skincare e skin-prep Made in Italy con Amore!
• Applied Computing — Applied Computing delivers industrial AI to the energy industry including oil and gas, refineries, and petrochemical plants, helping critical operations harness 100% of their data and optimise in real time for safer, faster, higher-performing decisions

Portfolio highlights

• Akamas — Akamas uses advanced application-aware AI to optimize performance, reduce cloud costs, and ensure reliability
• Volume — Payment Infrastructure for the Internet
• Cyberwave — Transform your industry with AI-defined robotics. Frictionless automation that makes advanced robotics accessible to manufacturers of all sizes.

Portfolio highlights

• Akeron Srl — Akeron Srl offers services such as implementation and training, managed services, support and houselab.

Portfolio highlights

• GHOSTDRIVE — The Ghostdrive leverages the decentralized nature of P2P networks (IPFS, and Filecoin) to provide unlimited data uploads. Unlike traditional centralized systems, where storage capacity is finite, P2P networks can dynamically expand their storage capabilities as more users join the network.
• Flanksource — Mission Control is an open-source, Kubernetes inspired internal developer portal that helps teams improve developer productivity and operational resilience.
• SEO Site Checkup — SEO Site Checkup offers webmasters, small business owners, and SEO agencies with SEO tools, software, and articles. It offers users with analysis and monitoring tools to analyze SEO issues of websites, to generate white-label SEO reports, to receive notifications on SEO score changes, and to understand their competitors’ SEO profiles.SEO SiteCheckup is operated from New York, United States.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• THRON — Siamo THRON. Quelli della piattaforma unica per governare insieme asset digitali e dati di prodotto, distribuendoli su tutti i tuoi canali di comunicazione.

Portfolio highlights

• KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• THRON — Siamo THRON. Quelli della piattaforma unica per governare insieme asset digitali e dati di prodotto, distribuendoli su tutti i tuoi canali di comunicazione.

Portfolio highlights

• Mela Works — Manage your work site with Mela, and generate logbooks and reports with one click. Download Mela now!
• unusuals — We are unusuals. We are AI. We are automatic detection. Take control of your infrastructure and start saving by unlocking visual data potential.