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Top 50 Biotechnology Startup Investors in Italy in January 2026

Last updated: Jan 2026 A list of 50 angel investors and VC (Venture Capital) funds that invest in Biotechnology startups based in Italy. We rank investors based on the number of investments they made in Biotechnology companies from Italy. We update this investor list every month.

Top 50 Biotechnology Startup Investors in Italy in January 2026

Investor	Biotechnology Italy investments
Sofinnova Partners	11
Italian Angels for Growth	9
Indaco Venture Partners	8
CDP Venture Capital	8
Vertis	7
LIFTT	6
Principia SGR	6
Innogest Capital	5
UniCredit	4
A11 Venture	4
Green Arrow Capital	4
Invitalia Ventures	3
INGENIUM Emilia Romagna	3
Atlante Ventures	3
Club degli Investitori	3
Progress Tech Transfer Fund	3
EUREKA! Venture SGR	3
Claris Ventures	3
Fondazione Cariverona	2
Barbara Castellano	2
Panakes Partners	2
Banco BPM	2
Italian Angels for Biotech	2
3B Future Health Fund	2
3LB Seed Capital Srl	2
European Investment Bank	2
Kering Ventures	2
Lazio Innova	2
StartUp Health	2
European Circular Bioeconomy Fund	2
Stefano Bernardi	2
Crédit Agricole Italia	1
Elena Paola Lanati	1
Utopia	1
Angels4Women	1
VI Partners	1
Istituto Nazionale Biostrutture e Biosistemi	1
Estor	1
FoolFarm	1
Deep Blue Ventures	1
MCF Holding	1
Exor Ventures	1
Deep Blue Ventures	1
NB Aurora	1
Maia Ventures	1
Angelini Ventures	1
United Ventures	1
Oskare Capital	1
FM Management	1
Lumen Ventures	1

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Investor list

Sofinnova Partners is a leading European venture capital firm in life sciences, specializing in healthcare and sustainability. Based in Paris, London and Milan, the firm brings together a team of professionals from all over the world with strong scientific, medical and business expertise.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
France, United States, United Kingdom

Portfolio highlights

DNA Script — DNA Script is a disruptive DNA synthesis company engineering biology to accelerate breakthroughs in life science and human health. Their revolutionary enzymatic technology powers the world's first benchtop DNA printer, SYNTAX, enabling labs to print their own synthetic oligos for greater workflow control and faster access to results.
AAVantgarde Bio — AAVantgarde Bio is developing gene therapies for inherited retinal disorders.
Excelsior Sciences — Rebuilding the World, From the Bottom Up

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
Rubedo Life Sciences — Rubedo Life Sciences is the Premier Longevity Company. Rubedo discovers and develops medicines to keep you biologically young.
Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

VENTURE We invest across all sectors with specific focus on technology and digital The largest independent more About Us Portfolio [...]

Investment focus

Biotechnology, Health Care, Life Science
Series A, Series B, Funding Round
Italy, Switzerland, United States

Portfolio highlights

Easy Rain — Easyrain pioneers active safety systems to prevent aquaplaning. We develop virtual sensors and hardware solutions to save lives on hazardous low-grip roads.
CamGraPhIC — Our platform supports the ever-increasing data traffic demand with high-performing and low-power consumption electro-optical engines.
Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Cubbit — Cubbit is secure encrypted cloud storage with a difference. A distributed cloud that is 100% private and green. Join the Swarm.
Titan4 — Titan4 provides products and services based on research combining different satellite data and sources for applications. They also provide development and integration, InSAR data analysis and data mining, geological analysis, and deep learning analytic services.
Dog Heroes — Dog Heroes delivers home recipes of fresh food, perfectly portioned to every dog's need. Only high-quality local ingredients are used in tailor-made portions that are ready to serve. Customers will find 55% meat of exclusively Italian origin in the company's recipes, balanced with vegetables, vitamins, and mineral salts. Dog Heroes doesnot use any chemical additives or preservatives.

Vertis is a dynamic and independent investment management company authorised by Bank of Italy. It manages five closed-end funds for qualified investors by participating in research projects, spin-offs, startups and PMI and deals with the investments of the innovative Made in Italy.

Investment focus

Software, Health Care, Computer
Seed, Series A, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Tuidi — Tuidi is a tech startup that develops predictive models of AI, with a particular focus on the food distribution sector. They combine methodical study of data, personalization of business processes and speed of integration for to return an output that is not only accurate but also free from interpretation difficulties so as to increase profits,reduce stock outages and optimize inventories.
Titan4 — Titan4 provides products and services based on research combining different satellite data and sources for applications. They also provide development and integration, InSAR data analysis and data mining, geological analysis, and deep learning analytic services.
Live Story Inc. — Forget about code and templates: with our freehand designable editor, you can quickly create layouts and publish them online in no time.

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Biotechnology, Software, Information Technology
Seed, Series A, Funding Round
Italy, United Kingdom, France

Portfolio highlights

QSensAto — QSensAto is a quantum sensing company specializing in the development and research of integrated vapor cells and quantum atomic sensors.
Agate Sensors — Agate Sensors offers equipment manufacturers advanced sensors that detect, identify, and classify people, vital signs, objects, and more. Their sensors come in a range of sizes, from single pixel devices to full matrix devices, and are produced using standard CMOS production processes, making them both cost-effective and efficient.
Sparrow Quantum — Sparrow Quantum, a global leader in quantum photonic chip technology. Explore innovative solutions driving advancements in quantum computing, communication, and beyond. Stay ahead with cutting-edge technologies shaping the future.

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

UniCredit is a pan-European commercial bank offering unique banking services in Italy, Germany, Central and Eastern Europe.

Investment focus

Energy, Manufacturing, Financial Services
Debt Financing, Post-IPO Debt, Funding Round
Italy, Germany, Sweden

Portfolio highlights

Noiet — Noiet is a biotechnology firm whose mission is to develop clean, natural, and fermented proteins that serve as multifunctional alternatives.
Peelpack — Peelpack is a packaging company that specializes in biodegradable and compostable biopolymer punnets, aiming to replace plastic packaging.
Alma Serum — Alma Serum is a cosmetic and biotech company that turns dairy industry into advanced cosmetic and biomedical materials.

A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi: scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.

Investment focus

Biotechnology, Medical Device, Health Care
Seed, Pre-Seed, Series A
Italy, United States

Portfolio highlights

Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Green Arrow Capital is an independent financial group specializing in alternative investments across Europe. They represent a one-of-a-kind platform, capable of connecting the financial system with the real economy through the management of private equity, private debt, infrastructure, and special credit situation funds as well as thematic fundssuch as microfinance and funds of funds that are currently under management. Their team has a successful track record in asset management, investment banking, industry sectors, technology startups, management consulting, renewable energy, and has government and regulatory experience. Their group is mainly composed of investment, asset management, and financial advisory companies. Their aim is to create a solid financial platform to launch and manage investment funds dedicated to alternatives and to the real economy.

Investment focus

Health Care, Biotechnology, Manufacturing
Funding Round, Seed, Series A
Italy, United Kingdom

Portfolio highlights

Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
Maticmind S.p.A — Maticmind S.p.A is a company that provides ICT and system integration solutions to telecommunications operators.
Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

INGENIUM Emilia Romagna was started with EUR 5.30 million by the Emilia Romagna region and EUR 1.7 million from fund managers. Managed by META Investment, the nine-year fund operated through the temporary acquisition of minority stakes in high-opportunity technological companies. It is now fully invested.

Investment focus

Medical, Health Care, Privacy
Seed, Angel, Funding Round
Italy

Portfolio highlights

CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

Atlante Ventures is a leading Italian VC fund, operated by IMI Fondi Chiusi SGR, part of Intesa Sanpaolo Group.

Investment focus

Software, Biotechnology, Hardware
Funding Round, Seed, Series A
Italy, United States, Israel

Portfolio highlights

treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.

Investment focus

Health Care, E-Commerce, Information Technology
Seed, Series A, Series B
Italy, Switzerland, United Kingdom

Portfolio highlights

Stema — It serves as a platform for hiring engineers
Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation
Annaida Technologies — Annaida Technologies has developed a groundbreaking device, EmbryoSpin, that performs microscopic Nuclear Magnetic Resonance (“µNMR”) at a scale 10-fold better than existing technologies.

Investment fund specialized in sustainable technologies from universities and public research organizations, start-ups, spin-offs, and entrepreneurs.

Investment focus

Biotechnology, Water, Manufacturing
Series A, Seed, Funding Round
Italy, Ireland, United Kingdom

Portfolio highlights

WembraneX — WembraneX's goal is to make wastewater treatment facilities more cost-effective by introducing a new class of anti-fouling and anti-biofouling membranes.
Naturbeads — Naturbeads creates biodegradable, sustainable and cost competitive cellulose microbeads to replace currently used microplastics.
Valuematic — Valuematic realizza soluzioni per il trattamento e gestione dei dati favorendo il miglioramento nei processi organizzativi e informativi di aziende ed enti.

Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments

Investment focus

Nanotechnology, Renewable Energy, Medical Device
Seed, Funding Round, Pre-Seed
Italy

Portfolio highlights

Caracol — Lead the future of manufacturing thanks to Caracol's 3D printing technologies. Discover our solutions for industrial, Large Format Additive Manufacturing.
FLEEPtech — FLEEP Technologies designs and develops printed electronics solutions for the biomedical and smart packaging sectors. The company, spin-off of Istituto Italiano di Tecnologia, was founded in May 2019.FLEEPtech developed a proprietary process for the fabrication of polymer-based integrated circuits based on Organic Thin-Film Transistors, creatingthe intelligent core for electronics systems that are mechanically flexible, printed like magazines and recyclable. FLEEPtech is the missing link in the printed electronics industry between a great number of flexible and printed products (i.e. sensors, actuators and energy supplies) that find little space in being integrated with standard non-flexible electronics. For such reasons, the company's mission revolves around the realization of a general purpose platform for the manufacturing of fully-printed integrated systems, composed by printed sensors, printed actuators, printed energy supplies and harvesters and, of course, printed integrated circuits.
INTA Systems — Nanotech and artificial intelligence for biomolecular analysis

Claris Ventures is a venture capital firm supporting the best scientists in building successful life sciences companies that will impact people's lives

Investment focus

Biotechnology, Health Care, Therapeutics
Seed, Series A, Series B
Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Fondazione Cariverona. Da oltre 25 anni per lo sviluppo civile, culturale ed economico di Verona, Vicenza, Belluno, Ancona e Mantova.

Investment focus

Venture Capital
Seed
Italy

Portfolio highlights

Noiet — Noiet is a biotechnology firm whose mission is to develop clean, natural, and fermented proteins that serve as multifunctional alternatives.
Peelpack — Peelpack is a packaging company that specializes in biodegradable and compostable biopolymer punnets, aiming to replace plastic packaging.
Alma Serum — Alma Serum is a cosmetic and biotech company that turns dairy industry into advanced cosmetic and biomedical materials.

Laura Iris Ferro

Investment focus

Health Care, Biotechnology, Medical Device
Pre-Seed, Funding Round
Italy

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.
CorFlow Therapeutics AG — CorFlow Therapeutics is a medtech startup that develops proprietary technologies for diagnosis and treatment of microvascular obstructions in heart attack patients. The CorFlow technologies enable interventional cardiologists to diagnose and treat MVO in severe heart attack patients thereby potentially reducing the short- and long-term complicationrates in these patients.

Panakès Partners is a Venture Capital firm, based in Milan, which invests in the most ambitious companies and teams, developing revolutionary technologies and products, in the field of life sciences, aiming to improve the lives of people around the world. Panakès, founded in 2015 by Fabrizio Landi, Alessio Beverina and Diana Saraceni, has 250million under management.

Investment focus

Health Care, Medical, Medical Device
Series B, Series A, Series C
Italy, Switzerland, United Kingdom

Portfolio highlights

DeepUll — DeepUll is a biotech company that focuses its activity on the development of a new diagnostic system for early-stage sepsis condition. DeepUll’s proposal is based on quickly identifying the pathogens and offering the antibiogram within a few hours on the one hand, and on using the data and learning about the patient’s immunological and functionalstatus on the other. The system allows doctors to predict the future appearance and evolution of sepsis within a short period of time and thus provide a suitable clinical response even before the symptoms arise.
Neuromod Devices — Neuromod is a medical device company formed to advance the science of bi-modal neuromodulation.We are committed to delivering treatments that significantly reduce the suffering of underserved patient populations who live with chronic and debilitating conditions globally. Our goal is to design products that empower patients to take control oftheir own treatment, delivering targeted therapies that integrate seamlessly into a modern lifestyle.Neuromod has developed and patented a bi-modal neuromodulation technology that it is evaluating for neurological disorders including chronic tinnitus, a condition affecting 10% of the adult population and commonly known as 'ringing in the ears'.
Salvia BioElectronics — Our mission is to give people with migraine a better life. As a pioneer in the field of medical devices, Salvia BioElectronics is passionately committed to empowering people with migraine to reclaim their lives.

Scopri i servizi bancari e finanziari di Banco BPM: conti, mutui, carte, prestiti, assicurazioni, trading e tanto altro. Per privati e imprese.

Investment focus

Manufacturing, Product Design, Energy
Debt Financing, Post-IPO Debt, Pre-Seed
Italy, United States, Spain

Portfolio highlights

NextChem — NextChem is the green chemistry subsidiary of Maire Tecnimont, an Italian multinational company specializing in engineering, technology, and energy. NextChem focuses on the energy transition by developing and deploying innovative solutions for sustainable industrial processes. It aims to accelerate decarbonization and promote the circular economythrough advanced technologies.
Bending Spoons — We own and operate leading digital products, including Evernote, komoot, Meetup, Remini, and WeTransfer. And we develop the technology to power them.
Maire Tecnimont — We are enablers of innovation, working alongside businesses to develop sustainable technologies and design integrated solutions that inspire energy transition.

Angel group focuses on biotech

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Helsinn Investment Fund S.A. is a Luxembourg fund focused on early-stage investments in areas of high unmet patient need.

Investment focus

Biotechnology, Therapeutics, Medical
Series B, Series A, Funding Round
United States, Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
Fore Biotherapeutics — We are a precision oncology company pioneering the development of cancer therapies guided by our proprietary functional genomics.
On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

3LB Seed Capital is not an alternative to start-ups incubators and accelerators, rather acts as a complementary reality that helps to enhance your project in terms of attractiveness for the investor and venture capital market.As investors they are the first willing to know if your project has what it takes to grow successfully. If they areconvinced of your potential, they are ready to bet on you, by joining you and helping you to develop your project.3LB Seed Capital does not provide a percentage of equity in exchange for accompanying activities, but relies exclusively on a premium at the time of its first direct investment in your company.

Investment focus

E-Commerce, Software, Information Technology
Seed, Pre-Seed, Series A
Italy, United States, United Kingdom

Portfolio highlights

YoAgents — Yo Agents nasce dalla unione delle competenze di ogni singolo founder messe a fattor comune per creare un sales hub innovativo.
Botsociety — Your conversational design suite. Design and prototype your next chatbot or voice assistant. Create a mockup of your project on Messenger, Slack, Google Assistant, Alexa and more. The next generation design solution for chatbots and voice.
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

The European Investment Bank (EIB) offers lending, borrowing, and treasury services primarily within the European Union. It provides project loans for public and private sectors, loans to banks and intermediaries, structured finance products, guarantees, and securitization instruments for debts. Additionally, EIB offers equity and fund investmentproducts, including infrastructure and environmental funds, as well as venture capital funds. EIB also supports microfinance and risk-sharing finance for research and innovation, and provides technical expertise for sustainable energy projects. Its services include infrastructure advisory, urban development support, guarantees for transport infrastructure, and funding for public-private partnerships and small- to medium-sized enterprises. The bank serves various sectors, including transportation, energy, health, education, and agriculture.

Investment focus

Biotechnology, Health Care, Energy
Debt Financing, Post-IPO Debt, Funding Round
France, Germany, The Netherlands

Portfolio highlights

Solynta — Welcome to the homepage of Solynta, leader in hybrid potato breeding and development of hybrid true potato seeds with attractive traits.
Evaxion Biotech — Evaxion Biotech A/S is a clinical-stage AI-immunology™ platform company decoding the human immune system to discover and develop novel immunotherapies to treat cancer and infectious diseases. Based on its proprietary and scalable AI-immunology core technology, Evaxion is developing a broad pipeline of novel product candidates which currentlyincludes three patient-specific cancer immunotherapies, two of which are in Phase I/IIa clinical development. In addition, Evaxion is advancing a portfolio of vaccines to prevent bacterial and viral infections with one program currently in preclinical development against S. aureus (including Methicillin-resistant S. aureus) induced skin and soft tissue infections.
Electrica — Electrica is a holding company involved in projects connected to the provision of power to final consumers as well as the development and operation of electrical distribution networks. It primarily serves as the principal electricity supplier in and throughout the town as well as an electricity distribution operator. The following segments make upthe company's business: electricity and gas supply, which is involved in acquiring and providing electricity and gas to end users, electricity generation, which produces electricity, electricity distribution, which offers services related to electricity distribution, external electricity network services, which provides maintenance, repairs, and other services for electricity networks owned by other distributors, and electricity distribution.

Kering Ventures is the venture investment arm of the Kering Group, acquiring minority holdings in startups.

Investment focus

Biotechnology, Interior Design
Series A
Italy

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
SQIM — SQIM is a biotechnological based agency.

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

doc-doc — Accede a los mejores especialistas en medicina, cuando y donde quieras.
Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
Biome Analytics — Providing doctors and hospitals precision insights needed to deliver better care at a lower cost. Cardiovascular program improvement, clinical performance applications, precision clinical and financial insights.

European Circular Bioeconomy Fund invest and partner with entrepreneurs to accelerate late-stage circular bioeconomy companies.

Investment focus

Biotechnology, AgTech, Agriculture
Series B, Series A, Series C
The Netherlands, France, Italy

Portfolio highlights

OroraTech — From safeguarding forests and ecosystems to protecting communities and critical assets, OroraTech's advanced technology and reliable insights address challenges, mitigate risks, and drive meaningful impact.
Elicit Plant — We work with farmers around the world to meet the challenges of climate change and the impact of water scarcity on field crops.
watttron — Watttron invents a revolutionary heating system that can heat up surfaces heterogeneously.Watttron develops an innovative heating technology that can be used in various industrial processes. It is superior to current heating systems in many ways and offers a number of advantages. On the following pages, you will find information about possibleapplications and opportunities.The company is located in the Technologie- und Gründerzentrum Freital – a technology and start-up center on the outskirts of Dresden, the state capital of Saxony.

Stefano Bernardi is the Investment Director, Climate at Fondazione ENEA Tech.

Investment focus

Biotechnology, Software, Artificial Intelligence
Seed, Pre-Seed, Funding Round
United Kingdom, Italy, France

Portfolio highlights

Freatic — Building the monetization layer for your alpha
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Automated Architecture — A global ecosystem of automated micro-factories, to deliver sustainable, affordable and beautiful architecture to millions of people.

Crédit Agricole Italia is a bank that offers loans and financial services.

Investment focus

Financial Services, Finance, Water
Debt Financing, Seed
Italy

Portfolio highlights

Ogyre —
FoolFarm — UN NUOVO MODO DI CREARE STARTUP Investiamo in imprenditori con idee rivoluzionarie in AI e Deep-tech. Offriamo supporto operativo ed investimenti per costruire aziende leader attraverso un metodo validato ed un team esperto in startup. CANDIDA LA TUA IDEA DIVENT
Krill Design — Krill Design is a design studio that creates circular economy projects to convert organic waste into material resources. It is a patented process that intercepts resources from the food supply chain to create zero-impact eco-designed 3D printed products.

Elena Paola Lanati

Investment focus

Biotechnology, Manufacturing, Nanotechnology
Seed
Italy

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.

Utopia is a venture capital firm that is dedicated to life sciences.Utopia SIS is an investment company specializing in healthcare and biomedical research, promoted and owned by the Golinelli Foundation.Utopia was established with the aim of bridging this gap, through investments in high-potential start-ups operating in the Life Sciencessector.

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

CaSRevolution — A novel disease-modifying approach against neurodegeneration

Angels4Women is a company that invests in business startups lead by females.

Investment focus

Retail, Fashion, Lingerie
Seed, Angel, Funding Round
Italy, United States

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
FUTURELY — FUTURELY is a platform which will help to choose university.
Chite Milano — Lingerie the Italian way. Discover 100% Made in Italy lingerie. Make your own: customise your lingerie and nightwear.

VI Partners are Venture Capitalists successfully financing outstanding teams and innovations in the Healthcare and Technology space since 20 years.

Investment focus

Health Care, Biotechnology, Medical Device
Series A, Series B, Series C
Switzerland, Germany, United States

Portfolio highlights

Xeltis — Xeltis is pioneering a restorative approach in cardiovascular therapy.
LeaseTeq — LeaseTeq bietet Privat- sowie Unternehmenskunden das erste komplett digitale Leasingangebot.
Unique — Try Unique Finance GPT to increase productivity by automating manual workload through AI and ChatGPT solutions.

Istituto Nazionale Biostrutture e Biosistemi is a platform for biostructures and biosystems that represent the intersection and the synthesis between the life sciences and physical sciences.

Investment focus

Wellness, Health Care, Biotechnology
Corporate Round
Italy

Portfolio highlights

Adamas Biotech — More than a decade of basic research in the field of botanical function-specific antioxidants. The nutraceutical solutions proposed to stem from a patented protected technology.

Estor is a Investment Firm.

Investment focus

Health Care, Biotechnology, Medical Device
Seed
Italy

Portfolio highlights

Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.

UN NUOVO MODO DI CREARE STARTUP Investiamo in imprenditori con idee rivoluzionarie in AI e Deep-tech. Offriamo supporto operativo ed investimenti per costruire aziende leader attraverso un metodo validato ed un team esperto in startup. CANDIDA LA TUA IDEA DIVENT

Investment focus

Software, Biometrics, Blockchain
Pre-Seed
Italy

Portfolio highlights

IIO — Il VoiceAgent AI visivo che parla, consiglia e accompagna i tuoi clienti all'acquisto. Personal shopping, raccomandazioni, recupero carrelli e supporto 24/7.
VoiceMe — SaaS solution of Voice Customer Authentication - a platform allowing electronic payments, single-sign-on and secured digital signing.

DEEP BLUE VENTURES Venture Capital Fund DEEP BLUE VENTURES DBV Deep Blue Ventures is our first Venture Capital fund DBV is an early stage deep tech fund, investing in outstanding deep technologies, and people able to harnessing them to great global success. Deep Blue Ventures

Investment focus

Biotechnology, Medical Device, Artificial Intelligence
Seed
Italy

Portfolio highlights

AI4IV — AI4IV is a start-up developing and marketing revolutionary bio-inspired vision sensor technology, combing the advantages of neuromorphic devices with those of digital CMOS devices. No other technologies currently available provide this unique combination or are based on similar concepts.Our vision sensor technology has already been validated withsilicon prototypes. We now aim at making available camera chips that can acquire images without artifacts even in the most challenging light conditions and extract the relevant information from the scene with an innovative on-die integrated AI processor.Our target use cases include autonomous vehicles, machine vision, robotics, security & surveillance and agriculture.
INTA Systems — Nanotech and artificial intelligence for biomolecular analysis

MCF Holding is a holding company of financial investments that engages in the management of events, retail, and real estate business.

Investment focus

Biopharma, Life Science, Biotechnology
Funding Round
Italy

Portfolio highlights

Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Exor Ventures is the venture capital arm of Exor, one of Europe's largest diversified holding companies. Exor Ventures focuses on early and growth-stage investments in technology-driven companies across various sectors, including digital services, fintech, cybersecurity, and mobility. Exor Ventures leverages its strategic insights and globalnetwork to identify promising startups with disruptive potential and supports them through funding, mentorship, and access to its extensive resources. EXOR Seeds offers a truly different type of partnership to the select group of entrepreneurs that it backs:- As a fifth-generation family-led business, we proved that we are builders not traders;- Our permanent capital allows us to take a long-term view and put the interest of the companies We invest in first;- Our global network, across industries and geographies, is a unique advantage to entrepreneurs

Investment focus

Software, Health Care, FinTech
Seed, Series A, Pre-Seed
United States, Italy, United Kingdom

Portfolio highlights

N5 Now — N5 has developed the way out of your complex legacy systems and into the fintech digital world, without having to change your core technology. Contact Us!
PhaseV — PhaseV empowers biopharma sponsors and CROs with AI/ML-driven solutions for fast, efficient, and accurate clinical development decisions.
Byzantine Finance — Stake assets, secure other services, and earn more. Restake now with Byzantine Finance to become part of DeFi's next generation. Building the most secure and profitable future for staking.

Deep Blue Ventures is an international holding company that acquires, manages, and scales the next generation of online brands.

Investment focus

Biopharma, Life Science, Biotechnology
Funding Round
Italy

Portfolio highlights

Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

NB Aurora supports entrepreneurs by providing professional management, governance, expertise and capital for growth and by leveraging its strong local presence and reputation with the global network of the Neuberger platform.

Investment focus

Bakery, Retail, Industrial
Private Equity
Italy

Portfolio highlights

PHSE — PHSE provides shipping solutions to biopharma, healthcare, and pharmaceutical companies.
Farmo — Farmo processes and supplies a wide range of food products such as pasta, salty snacks, cake, biscuits, mix and ready meals.
Rino Mastrotto Group S.p.A. — Rino Mastrotto Group S.p.A. produces and supplies leather products.

Seeding change investing in category-defining agri & foodtech ventures.

Investment focus

Medical, Software, Health Care
Series A, Funding Round
Italy

Portfolio highlights

Biorsaf — Biorsaf is an IT company that develops mobile apps and web control panels to assist companies to bring efficiency to their operations.
Lembas — Lembas is a foodtech startup that has developed "GLP-1 Edge," a patent-pending peptide ingredient designed to naturally boost the GLP-1 hormone, which helps regulate appetite and metabolism for weight management. Using AI-driven discovery and licensed technology from Tel Aviv University, Lembas offers this peptide powder as abusiness-to-business ingredient for food and supplement brands, providing a science-backed, non-pharmaceutical alternative to weight loss drugs with no reported side effects
ExoLab Italia — Cosmetics Utilizing plant-derived exosomes in cosmetic products boosts skin absorption, enhancing bioavailability and stimulating cells to produce lacking compounds. Their ability to penetrate the dermis ensures maximum efficacy and optimal results for skincare products. more informations Supplements Plant-derived exosomes, rich in nutrients, enhance bioavailability by

Angelini Ventures is an investment firm.

Investment focus

Health Care, Therapeutics, Biotechnology
Series A, Series B, Series C
United States, Italy, Belgium

Portfolio highlights

Biovitae — Benvenuto sul sito ufficiale di Biovitae, la tecnologia italiana brevettata per la sanificazione degli ambienti.
Nuevocor — Nuevocor is a preclinical-stage biopharmaceutical company focused on developing gene therapy‑based treatments that have the potential to restore cardiac function in diseased hearts.
Nuclidium — NUCLIDIUM is a clinical-stage radiopharmaceutical company that develops novel radionuclide PET tracers for precision diagnostics. Using copper isotopes, Copper-61 for diagnostics and Copper-67 for therapeutics, the company is creating a differentiated platform with the potential to overcome existing limitations in radiotheranostics.

We are an independent Venture Capitalfirm supporting visionary entrepreneurs toreinvent industries through technology.

Investment focus

Software, FinTech, Information Technology
Series A, Seed, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Exein — Exein provides the most advanced IoT security solution to protect your devices and containers. Protect your IoT devices in real time and at scale.
Avaneidi — Discover Avaneidi's enterprise storage solutions. Designed in Italy with a 'security by design' approach for unparalleled security and reliability.
IdentifAI — IdentifAI pioneers discerning human-AI creations, bolstering authenticity with advanced models. Determine if an image come from AI or from human!

Oskare Capital is a venture capital firm.

Investment focus

Health Care, Biotechnology, Medical
Seed, Pre-Seed, Series A
Italy, Denmark, United Kingdom

Portfolio highlights

Leva Clinic — Leva Clinic offers health care services for people with chronic pain. Their medical services include back pain, cancer pain, endometriosis, facial pain, fibromyalgia, joint pain, knee pain, multiple sclerosis, sciatica, and so on.
Octarine Bio — Octarine Bio is a synthetic biology company that produces superior cannabinoids for the pharmaceutical industry.
Herbolea Biotech — Unique bio-processing technologies NATURAL, SOLVENT-LESS Botanical extraction Learn more

FM Management is a private equity firm focused on the growth and development of small- and medium-sized companies.

Investment focus

Health Care, Biotechnology, Pharmaceutical
Series A
Italy

Portfolio highlights

Erydel — Based in Urbino, EryDel has developed and patented a technology for drug delivery of pharmacological agents through erythrocytes (red blood cells). This process allow to easily load red blood cells with drugs, proteins, contrasting agents for diagnostic purposes, nanoparticles etc. that can be progressively released into the patient body thusallowing an increased efficacy of the therapy and a reduction of collateral effects. The benefit is extremely significant particularly for chronic pathologies that requires continuous daily treatments for patients which could be substituted by monthly transfusion of blood loaded with specific therapeutic agents. Currently, the solution has been tested by several patients for the treatment of Inflammatory Bowel Diseases (IBDs) such as ulcer colitis and Crohn disease. The company can provide a complete support for the drug delivery process including a specific device for the erythrocytes loading ("Red Cell Loader"), and disposable kits.
Datamars — Datamars was founded in 1988 as a joint venture between the technology companies Datalogic and Audemars to develop, design and manufacture state-of-the-art RFID solutions. The company quickly established itself as a world leader in RFID solutions for the animal and textile identification markets.

Lumen Ventures is a venture capital firm that focuses on seed investments, early-stage investments, and private equity.

Investment focus

B2B, E-Commerce, Food and Beverage
Seed, Pre-Seed, Series A
Italy

Portfolio highlights

Macai — Ceramica di Caltagirone. Bomboniere Pigne e Teste di Moro. Autentica ceramica siciliana, bomboniere siciliane . Ceramiche Online
GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
Insoore — Insoore is a platform that helps insurance companies to improve the claims management process, thanks to on-demand photographic inspections and damage estimates provided by a community of experts.

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