Top 15 Local Startup Investors in Italy (September 2026)

Portfolio highlights

• Cosmico — We are the platform connecting digital talents with the most ambitious companies, using remote work.We have over 8,000 members and our talents have accelerated dozens of projects alongside big names like Accenture Song, Tangity, Frog, Fjord, Sketchin, EY but also aggressive start-ups like Scalapay, Gimme5, Flowe, Unguess.If you are a digitalprofessional: we offer you a community in which to grow your talent through experiences, networks and cosmic projects.If you are a company: we offer you access to a community of designers, developers and marketers from which to select the talents to accelerate your digital transformation projects. Whether you are a manager or a digital professional, Cosmico is here to help you find your space
• A-Cube — A-Cube API: la piattaforma globale per la Tax Compliance. Integra la fatturazione elettronica e gli obblighi fiscali in ogni ERP o e-commerce in Italia e nel mondo.
• Incapto Coffee — Incapto provides coffee solutions that combine specialty whole-bean coffee, super-automatic coffee machines, and subscription-based delivery services for consumers and businesses. The company supplies freshly roasted coffee beans sourced from multiple origins and delivers them directly to customers through recurring subscriptions, ensuringcontinuous availability and freshness. Its offering includes fully automatic coffee machines that grind and brew beans on demand, enabling users to prepare coffee without single-use capsules or manual preparation steps. The company also provides workplace coffee solutions, supplying machines, beans, and technical support for offices, hotels, and food service environments.Incapto integrates digital tools that track consumption, manage inventory, and automate replenishment, allowing customers to monitor usage and receive supplies based on demand. It also offers complementary products such as accessories, beverages, and maintenance services to support ongoing operation of its coffee systems.

Portfolio highlights

• CityNews — Citynews is an italian based network of local newspaper sites. Actually active in 9 cities Citynews planning to open in the 30 principal italian cities. Actually 1,4 million visits each months.
• Fitprime — Il Partner unico per il Wellbeing Aziendale

Portfolio highlights

• UNGUESS (formerly AppQuality) — UNGUESS is the crowdsourcing platform for effective testing and real insights. Take the guesswork out of your work.
• Paragraph — Paragraph turns your startup's launches, product updates, customer learnings, and founder thinking into an owned media engine your team approves.
• La Passione — High quality Italian Road and Urban cycling wear at fair prices. We use only the finest materials and sell direct to you with no middleman. Shop now!

Portfolio highlights

• HEU — Draft, sign and store contracts in one place. AI extracts deadlines and clauses, signatures valid in 180+ countries.
• Tech4All — We support the study by using AI.
• GeneSys Bio — Antimicrobial Resistance (AMR) is a global health emergency projected to cause 10 million deaths annually by 2050. The crisis is fueled by slow, conventional diagnostics that take 3-5 days, forcing the empirical use of broad-spectrum antibiotics and accelerating the spread of superbugs.GeneSys Bio is commercialising a breakthrough solution: afully automated, sample-to-result molecular diagnostic platform that identifies infectious pathogens and their critical antibiotic resistance genes in under 30 minutes with >99% sensitivity and specificity. Our portable, laptop-sized device combines proprietary nucleic acid amplification with an AI-driven engine to deliver clear, actionable results directly to clinicians, veterinarians, and public health officials.Our platform is a modular "One Health" solution, adaptable via disease-specific kits for human, veterinary, and environmental applications. We are entering the market with a diagnostic for Urinary Tract Infections (UTIs), a condition affecting over 500 million people annually and a primary driver of antibiotic misuse. By enabling targeted therapy at the first patient encounter, our platform is set to reduce treatment costs by up to 13%, cut follow-up visits, and decrease mortality from complicated infections by 50%.GeneSys Bio is positioned to capture a significant share of this market by bridging the critical gap between speed, laboratory-grade accuracy, and accessibility. We are not just creating a device; we are building the future of decentralized infectious disease diagnostics to safeguard global health for generations to come

Portfolio highlights

• Shawton Energy — Shawton Energy provides innovative, sustainable energy solutions that help businesses reduce their carbon footprint, cut costs and optimise efficiency. Discover how we can power your business toward a greener future.
• North West Biomass Ltd — North West Biomass Ltd owns and operates a combined heat and power generation plant.
• Carbon Capture Scotland — Carbon Capture Scotland seeks to get rid of carbon dioxide that has been organically stored in grains and barley.

Portfolio highlights

• Loquis — La prima piattaforma per ascoltare e raccontare il mondo tramite podcast geolocalizzati
• Intron Health — Intron provides clinical speech recognition for 200+ accents spoken in developing countries starting with Africa, reducing documentation time by 6x so doctors can spend more time with patients
• Cyberwave — Transform your industry with AI-defined robotics. Frictionless automation that makes advanced robotics accessible to manufacturers of all sizes.

Portfolio highlights

• Archimede — Deep tech company based in Sicily #archmesh is our satellite kit
• Mirai Robotics — Autonomy and intelligence for the seas. We're building software-defined autonomous systems and AI platforms that unify vessels, sensing, and command at sea.
• Quantum Bridge — Quantum Bridge is a pioneer in Distributed Symmetric Key Exchange (DSKE) technology. It offers quantum-safe cybersecurity products and services. Quantum-safe product and services, Quantum-safe roadmap and quantum-safe solutions implementation.

Portfolio highlights

• PerMicro — PerMicro: credito e microcredito per l'inclusione. Al fianco di startup, micro e piccole imprese e famiglie con esigenze primarie.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• iRaiser — Elevate your charity fundraising with iRaiser's tailored solutions. Trusted by over 850 charities globally. Boost donations, engage supporters, and track success effortlessly. Unleash generosity today!
• EatRight — EatRight are into packaging of fresh and good quality food products.
• Trapview — Trapview provides automated pest monitoring and forecasting tools for agriculture, forestry and food storage. Get real-time insights and reduce insecticide use.

Portfolio highlights

• Vestinda — Vestinda is the platform that provides investments in digital assets. Their features are portfolio tracking, crypto portfolio tracking, strategy libraries,crypto investment strategies,strategy builders, trading strategies built with no code, backtesting backtested crypto trading strategies,demo trading,crypto paper trading, and risk-free livetrading.
• LIA — Lia gestisce fatture, solleciti e piani di rientro in autonomia: tu mantieni la visione sul cashflow, sui clienti e sulle decisioni che contano.
• Lendit — Lia gestisce fatture, solleciti e piani di rientro in autonomia: tu mantieni la visione sul cashflow, sui clienti e sulle decisioni che contano.

Portfolio highlights

• Linkem — Linkem ti offre Internet senza linea fissa per la tua casa grazie alla tecnologia FWA. Naviga senza limiti di traffico.
• PerMicro — PerMicro: credito e microcredito per l'inclusione. Al fianco di startup, micro e piccole imprese e famiglie con esigenze primarie.
• Green Arrow Capital — Piattaforma indipendente italiana leader negli investimenti alternativi.

Portfolio highlights

• CityNews — Citynews is an italian based network of local newspaper sites. Actually active in 9 cities Citynews planning to open in the 30 principal italian cities. Actually 1,4 million visits each months.

Portfolio highlights

• SeqOne Genomics — Healthcare is undergoing a revolution, known as genomic medicine, that uses the patient’s genomic information to optimise treatment. This trend is accelerating thanks to the arrival of New Generation Sequencing (NGS) techniques that have reduced the cost of decoding genomic material while increasing the amount useful data obtained. However, NGShas had only limited impact on mainstream healthcare due to the difficulties in analyzing more and richer genomic data. SeqOne’s mission is to provide tools that enable the healthcare industry to analyse NGS genomic data better and more cost-effectively to provide universal access to genomic medicine.
• Adictiz — Adictiz, a French company founded in 2009 by Charles Christory, develops and publishes social games for the web and mobile phones.With successful brands including “Space Dog” and “What a Stupid Pigeon”, which attract close to 2.5 million players every month, Adictiz has established itself as an expert player in social and mobile gaming.Basedat the EuraTechnologies economic excellence hub in Lille, which is dedicated to serving information and communication technology companies, Adictiz set up Adictiz Studio in late 2011, which specialises in the creation of customised social games for brands. Adictiz Studio was recently selected by Facebook as a PMD (Preferred Marketing Developer).
• Complix — Complix is a biopharmaceutical company focused on the discovery and development of Alphabodiesâ„¢, a novel class of biopharmaceuticals that offer significant advantages over existing protein based therapies. Alphabodiesâ„¢ bind with high affinity to a wide range of disease targets and are particularly suited to address certain targets that aredifficult to reach with antibodies or other types of protein scaffolds. Due to their unique stability and versatility Alphabodiesâ„¢ can be delivered via alternative non-injectable routes of administration, unlike most therapeutic proteins.

Portfolio highlights

• CityNews — Citynews is an italian based network of local newspaper sites. Actually active in 9 cities Citynews planning to open in the 30 principal italian cities. Actually 1,4 million visits each months.