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Top 50 Biotech Startup Investors in Italy

Last updated: Apr 2024 A list of 50 angel investors and VC funds that invest in Biotech startups based in Italy. We rank investors based on the number of investments they made in Biotech companies from Italy. We update this investor list every month.

Top 50 Biotech Startup Investors in Italy

Investor	Biotech Italy investments
Sofinnova Partners	11
Italian Angels for Growth	9
Indaco Venture Partners	7
Vertis SGR S.p.A.	7
Principia SGR	6
Innogest Capital	6
LIFTT	5
Invitalia Ventures	4
Atlante Ventures	4
Green Arrow Capital	4
A11 Venture	4
CDP Venture Capital	3
Club degli Investitori	3
Claris Ventures	3
Eureka Venture	3
StartUp Health	2
Lazio Innova	2
INGENIUM Emilia Romagna	2
Progress Tech Transfer Fund	2
Italian Angels for Biotech	2
3B Future Health Fund	2
UniCredit Group	2
Laura Iris Ferro	2
European Investment Bank	2
F3F	1
Forbion Capital Partners	1
MVM Life Science Partners	1
Andrea Dusi	1
Pi Campus	1
Deep Blue Ventures	1
Oskare Capital	1
Seroba Life Sciences	1
Scientifica Venture Capital	1
Stefano Bernardi	1
Crédit Agricole Italia	1
Lumen Ventures	1
Index Ventures	1
Angels4Women	1
Launch Tennessee	1
Embed Capital	1
Atlas Venture	1
European Circular Bioeconomy Fund	1
RECOMEC	1
Enrico Pandian	1
Riso Gallo	1
Istituto Nazionale Biostrutture e Biosistemi	1
Kering Ventures	1
Schia Ventures	1
Intesa Sanpaolo	1
European Commission	1

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Investor list

Sofinnova Partners is a leading European venture capital firm in life sciences, specializing in healthcare and sustainability. Based in Paris, London and Milan, the firm brings together a team of professionals from all over the world with strong scientific, medical and business expertise.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
France, United States, United Kingdom

Portfolio highlights

Cure51 — Cure51 mission is to create a database of cancer survivors to leverage their exceptional biological features and find new drugs to cure Cancer.
Bioptimus — Our mission is to build the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovations in biomedicine and beyond.
MISSION Therapeutics — Deubiquitylating enzymes: multiple drug opportunities across therapeutic areas

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Viceversa — Viceversa provides capital to European digital businesses to support companies in sustainable and ethical growth. The company was founded in 2021 and has locations in Milan and Dublin.
Clearbox AI — Benefit from Synthetic Data to unlock your AI projects, overcome privacy issues and improve the utility of your data.

VENTURE We invest across all sectors with specific focus on technology and digital The largest independent more About Us Portfolio [...]

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
Easy Rain — We are Easyrain. Continuous innovation runs in our blood.With our expertise, we develop, simulate, and test solutions, launching our ideas into production. We exploit the basic laws of physics to engineer a tangible solution!
Alia Therapeutics — Alia Therapeutics is developing next-generation gene-editing medicines to cure rare genetic diseases.

Vertis is a dynamic and independent investment management company authorised by Bank of Italy. It manages five closed-end funds for qualified investors by participating in research projects, spin-offs, startups and PMI and deals with the investments of the innovative Made in Italy.

Investment focus

Software, E-Commerce, Computer
Seed, Funding Round, Series A
Italy, United States

Portfolio highlights

NEWTWEN — We develop software that generates real-time embedded digital twin solutions for model predictive control and diagnostics of electromechanical systems, enhancing performance, longevity, and reliability. In essence, our toolchain creates a precise digital replica of a physical device, such as an electric motor or generator, in order to accuratelymodel the electrodynamic and thermodynamic behavior of the system across a wide range of operating conditions. We then apply our proprietary mathematical approach to exponentially reduce the computational complexity of this model—so much so, in fact, that our digital twin can be integrated into the device itself to compute in real-time, “on-chip,” as part of an amazingly fast and accurate firmware solution. By accurately predicting temperatures and other critical system parameters thousands of times per second, our Digital Twin On-Chip solutions not only provide unprecedented insight for real-time control techniques to enhance system performance, but also pave the way for data-as-a-service capabilities such as predictive maintenance, monitoring of component aging, and anomaly detection.
Coverzen — The digital office of insurers
Sibylla Biotech — Sibylla Biotech developed small molecule folding interfering degraders (FIDs) that can address a range of therapeutic areas.

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Software, Biotechnology, Health Care
Seed, Series A, Funding Round
Italy, United Kingdom, Switzerland

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
SteerLight — SteerLight is a startup that develops LiDAR-based optical sensors, also known as laser-based optical systems, to aid with mobility.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Atlante Ventures is a leading Italian VC fund, operated by IMI Fondi Chiusi SGR, part of Intesa Sanpaolo Group.

Investment focus

Software, Biotechnology, Hardware
Funding Round, Seed, Series A
Italy, United States, Israel

Portfolio highlights

treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Green Arrow Capital is an independent financial group specializing in alternative investments across Europe. They represent a one-of-a-kind platform, capable of connecting the financial system with the real economy through the management of private equity, private debt, infrastructure, and special credit situation funds as well as thematic fundssuch as microfinance and funds of funds that are currently under management. Their team has a successful track record in asset management, investment banking, industry sectors, technology startups, management consulting, renewable energy, and has government and regulatory experience. Their group is mainly composed of investment, asset management, and financial advisory companies. Their aim is to create a solid financial platform to launch and manage investment funds dedicated to alternatives and to the real economy.

Investment focus

Health Care, Biotechnology, Manufacturing
Funding Round, Seed, Series A
Italy, United Kingdom

Portfolio highlights

Cogisen — Cogisen develops artificial intelligence solutions. It offers SENCOGI, an eye-tracking software for smartphones/mobile phones. Chiara Passacantilli and Christiaan Erik Rijnders founded Cogisen in 2009. Its headquarters is in Naples in Italy.
Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi: scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.

Investment focus

Biotechnology, Medical Device, Health Care
Seed, Pre-Seed, Series A
Italy, United States

Portfolio highlights

Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
Italy, United States, Germany

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
Voidless — VOIDLESS is the new generation of box-on-demand packaging. An innovative system that bets everything on reliability and integrability.
Daze — Discover Daze's innovative electric car charging systems. The only charging systems with integrated load balancing.

Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.

Investment focus

E-Commerce, Health Care, Software
Seed, Series A, Funding Round
Italy, United Kingdom, Israel

Portfolio highlights

Algor Education — Algor Lab is a company that provides tools and materials needed for teaching through artificial intelligence.
CarpeCarbon — CarpeCarbon is a company that develops technologies for Direct Air Capture (DAC) to extract CO2 directly from the atmosphere. Based in Italy, with a Global vision, the company is made of young researchers (Physics, Chemistry, Astrophysics, Biology, Complex Systems, Engineering) and economists.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.

Claris Ventures is a venture capital firm supporting the best scientists in building successful life sciences companies that will impact people's lives

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Repron Therapeutics — Repron Therapeutics provides treatments for solid tumor cases where radical excision is not possible and metastasis or recurrence is extremely likely.

Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments

Investment focus

Nanotechnology, Renewable Energy, Medical Device
Funding Round, Seed, Pre-Seed
Italy

Portfolio highlights

Planckian — Charging the future by powering energy with science We explore frontiers of energy science by developing quantum...
INTA Systems — INTA Systems is a developer of lab-on-a-chip for biomolecular analysis through the combination of nanotech and artificial intelligence.
BeDimensional — We produce graphene and others two-dimensional materials (2D) with few atomic layers. Find out more.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
Pear Suite — Pear Suite enables anyone—community health workers, other healthcare staff, and volunteers—to assess and address the social drivers of health for older adults in a scalable, cost-effective, and person-centered way.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Health Care, Software, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

INGENIUM Emilia Romagna was started with EUR 5.30 million by the Emilia Romagna region and EUR 1.7 million from fund managers. Managed by META Investment, the nine-year fund operated through the temporary acquisition of minority stakes in high-opportunity technological companies. It is now fully invested.

Investment focus

Medical, Health Care, Privacy
Seed, Angel, Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.
GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

Investment fund specialized in sustainable technologies from universities and public research organizations, start-ups, spin-offs, and entrepreneurs.

Investment focus

Water, Eyewear, Farming
Seed, Pre-Seed, Series A
Italy, Ireland

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
Valuematic — Valuematic realizza soluzioni per il trattamento e gestione dei dati favorendo il miglioramento nei processi organizzativi e informativi di aziende ed enti.
HT Materials Science — HT Materials Science provides nanofluid science in thermal systems for commercial and industrial infrastructure.

Angel group focuses on biotech

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Helsinn Investment Fund S.A. is a Luxembourg fund focused on early-stage investments in areas of high unmet patient need.

Investment focus

Biotechnology, Medical, Biopharma
Series B, Series A, Funding Round
United States, Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
Sibylla Biotech — Sibylla Biotech developed small molecule folding interfering degraders (FIDs) that can address a range of therapeutic areas.
On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

UniCredit Group is an Italian global banking and financial services company. Its network spanning 50 markets in 20 countries, with more than 9,000 branches and over 148,000 employees. Its strategic position in Western and Eastern Europe gives the group one of the region's highest market shares.

Investment focus

Software, Financial Services, Banking
Debt Financing, Funding Round, Post-IPO Debt
Italy, Germany, Sweden

Portfolio highlights

Ecopol — The Ecopol's PVA water-soluble film technology is the world leading solution in packaging applications, such as detergents, agrochemicals, etc.
Edison Spa — Edison S.p.A is an energy company in the field of electricity and natural gas.
Goglio Group — Goglio Group produces full trademark food packaging.

Laura Iris Ferro

Investment focus

Health Care, Biotechnology, Medical Device
Pre-Seed, Funding Round
Italy

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.

European Investment Bank (EIB) provides lending, borrowing, and treasury services primarily in the European Union.The company offers project loans for the public and private sectors; loans to banks and other intermediaries; structured finance products; guarantees and securitization instruments for senior and subordinated debts; project bonds;equity and fund investment products such as infrastructure equity and debt funds, and environmental funds; and venture capital funds and security packages for funds.The company also offers microfinance; risk sharing finance for research, development, and innovation projects; finance and technical expertise for sustainable energy projects; infrastructure project advisory services; support for urban development projects; guarantees for transport infrastructure; and funding for public-private partnerships and small- and medium-sized enterprises.EIB serves the transportation, global loans, energy, industry, health, education, water, sewerage, infrastructure, services, telecommunications, agriculture, and fisheries sectors.European Investment Bank was founded in 1958 and is based in Luxembourg.

Investment focus

Biotechnology, Health Care, Software
Debt Financing, Post-IPO Debt, Funding Round
France, Germany, The Netherlands

Portfolio highlights

Eldrive — The largest charging point operator in Eastern Europe | Our network is expanding rapidly yet our focus is fixed on renewables, for a greener future. We provide AC & DC charging across Bulgaria, Romania and Lithuania.
ABN AMRO Bank — Als bank leggen wij de focus op inclusiviteit, duurzaamheid, sociaal ondernemen, innovatie, dagelijkse bankzaken en meer.
Enel Green Power — Enel Green Power is the company that deals with renewable energy from every perspective: from direct sales through PPA, to commitment at the forefront with its plants worldwide.

F3F

Investment focus

Hardware, Hospital, Software
Series A, Series C
Italy

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Impacting the future of medicine.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, United Kingdom, The Netherlands

Portfolio highlights

Kynexis — Kynexis is leading the way in precision medicine, focusing on the treatment of cognitive impairment associated with schizophrenia (CIAS). Explore our innovative approach and our dedication to improving the lives of millions globally.
Calluna Pharma — Join Calluna Pharma on our mission to revolutionize the treatment of inflammatory and fibrotic diseases. With a robust pipeline, seasoned leadership, and strategic alliances, help us reshape the treatment landscape for the better.
Orbis Medicines — Orbis Medicines is a novel macrocyclic chemistry and computational platform for high-throughput drug discovery.

MVM invests in innovative healthcare companies. Our active portfolio companies are transforming the delivery of healthcare by enabling higher quality, cost-effective care in large, global markets.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series B, Series C
United States, United Kingdom, Switzerland

Portfolio highlights

Icotec — Icotec develops and produces carbon fiber reinforced plastic implants for spine surgeries and accident treatments.
Gynesonics — Gynesonics is a women’s healthcare company focused on the development of advanced incision-free solutions for the treatment of uterine conditions. Gynesonics serves customers worldwide. It was founded in 2005 and is headquartered in Redwood City, California.
Nalu Medical — Nalu Medical is an early-stage company that develops a range of medical devices. Their vision to modernize and improve the technology in medical devices, thus improving the lives of people.The Nalu neurostimulation system is a battery-free, micro-implantable pulse generator (iPG) currently cleared by the FDA for both Spinal Cord Stimulation (SCS)and Peripheral Nerve Stimulation (PNS) for mitigating chronic pain. The company was founded in 2014 and is based in Carlsbad, California.

Entrepreneur and investor. After working in management consulting, in 2006 he created Wish Days, known above all for the Emozione3 gift boxes. In April 2016, he sold the company to the Smartbox group with a millionaire exit. In 2017, together with Cristina Pozzi, already a partner in Wish Days he founded Impactscool.He is advisor of dozens oftechnological initiatives and business angels in 150+ startups focusing on clean tech.He is the author of the book “Come far fallire una startup ed essere fellici” – How to make a startup fail and be happy, published by Bompiani, Bestseller in 2018.

Investment focus

Biotechnology, Health Care, Information Technology
Seed, Pre-Seed, Series A
Italy, United States, United Kingdom

Portfolio highlights

Talyn Air — Inspired by two-stage rockets, our innovative eVTOL uses two flight vehicles to transform flight. Fixed-wing performance with VTOL capabilities.
BillionToOne — We are a team at the forefront of disease detection focused on moving Prenatal Screening and Liquid Biopsy forward.
CaSRevolution — A novel disease-modifying approach against neurodegeneration

Pi Campus is a startup district and a venture fund that invests in talent. We provide startups with money, mentorship and the best work environment for growth.

Investment focus

Software, Mobile, Biotechnology
Seed, Pre-Seed, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Fondo — Fondo is an all-in-one accounting platform for startups. We'll handle your bookkeeping, tax, and tax credits so you can focus on building your startup.
Turion Space — Turion Space provides a spacecraft to remove orbital debris and services to existing satellites. The spacecraft will rendezvous and dock with current satellites and large debris objects using vision sensors and robotic arms. Utilizing the onboard propulsion system, the spacecraft will either deorbit or change the orbit of the debris object orsatellite.
Sixfold Bioscience — Sixfold Bioscience engineers programmable oligonucleotide delivery systems are able to deliver RNA exclusively to diseased cells. It is based in London.

DEEP BLUE VENTURES Venture Capital Fund DEEP BLUE VENTURES DBV Deep Blue Ventures is our first Venture Capital fund DBV is an early stage deep tech fund, investing in outstanding deep technologies, and people able to harnessing them to great global success. Deep Blue Ventures

Investment focus

Biotechnology, Medical Device, Artificial Intelligence
Seed
Italy

Portfolio highlights

INTA Systems — INTA Systems is a developer of lab-on-a-chip for biomolecular analysis through the combination of nanotech and artificial intelligence.

Oskare Capital is a venture capital firm.

Investment focus

Health Care, Biotechnology, Medical
Seed, Pre-Seed, Series A
Italy, Denmark, United Kingdom

Portfolio highlights

Leva Clinic — Leva Clinic offers health care services for people with chronic pain. Their medical services include back pain, cancer pain, endometriosis, facial pain, fibromyalgia, joint pain, knee pain, multiple sclerosis, sciatica, and so on.
Octarine Bio — Octarine Bio is a synthetic biology company that produces superior cannabinoids for the pharmaceutical industry.
Herbolea Biotech — Unique bio-processing technologies NATURAL, SOLVENT-LESS Botanical extraction Learn more

Seroba is a leading European life sciences venture capital firm focused on value creation through backing winning biotech innovations.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Funding Round
Ireland, United States, United Kingdom

Portfolio highlights

Shorla Pharma — Shorla Pharma is an Irish specialty pharmaceutical company. It is growing portfolio brings accessible, affordable and life-saving treatments to patients, delivering a major contribution to patient care and providing a significant clinical impact.
Storm Therapeutics — Targeting pathways that modify RNA to deliver novel cancer therapeutics.
Artica Therapeutics — Artica Therapeutics specializes in biotechnological research and development for medical devices, pharmaceutical processes, and food.

Scientifica Venture Capital offers private equity and venture capital investment services for Italy based startups and firms.

Investment focus

Medical, Biotechnology, Manufacturing
Seed, Private Equity
Italy

Portfolio highlights

Relicta — Relicta solution is a water-soluble bioplastic material obtained from fish processing waste and suitable for packaging solutions.
OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
QuantaBrain — QuantaBrain purpose is to accelerate the diagnosis of psychiatric and neurodevelopmental diseases by applying artificial intelligence.

Stefano Bernardi is the Investment Director, Climate at Fondazione ENEA Tech.

Investment focus

Software, Biotechnology, Artificial Intelligence
Seed, Pre-Seed, Funding Round
Italy, France, Norway

Portfolio highlights

Freatic — We bridge the gap between individuals with untapped knowledge and actors who can take advantage of these opportunities.
Eden Bio — Eden Bio is a biotech using machine learning to guide the genetic engineering of microorganism strain optimisation, improving protein yield.
CaSRevolution — A novel disease-modifying approach against neurodegeneration

Crédit Agricole Italia is a bank that offers loans and financial services.

Investment focus

Water, Farming, Software
Debt Financing, Seed
Italy

Portfolio highlights

Ecopol — The Ecopol's PVA water-soluble film technology is the world leading solution in packaging applications, such as detergents, agrochemicals, etc.
Finapp — Finapp is an innovative startup that produces a new generation of CRNS probes that allow measuring the water content. Water in the ground, then soil moisture, water out of the ground, then in the biomass, water in the snow, then snow water equivalent. The applications are really many, such as the research of water losses along aqueducts,hydrological and hydraulic modeling, estimates of hydroelectric energy but mainly agricultural ones.
Generalfinance — Generalfinance is a financial management agency that provides flexible services designed to address the company's debt issues.

Lumen Ventures is a venture capital firm that focuses on seed investments, early-stage investments, and private equity.

Investment focus

B2B, E-Commerce, Food and Beverage
Seed, Pre-Seed, Series A
Italy

Portfolio highlights

Macai — Ceramica di Caltagirone. Bomboniere Pigne e Teste di Moro. Autentica ceramica siciliana, bomboniere siciliane . Ceramiche Online
GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
Insoore — Insoore is a platform that helps insurance companies to improve the claims management process, thanks to on-demand photographic inspections and damage estimates provided by a community of experts.

Index Ventures is an international venture capital firm with dual headquarters in San Francisco and London, investing in technology-enabled companies with a focus on e-commerce, fintech, mobility, gaming, infrastructure/AI, and security.

Investment focus

Software, E-Commerce, Internet
Series A, Series B, Seed
United States, United Kingdom, France

Portfolio highlights

SESO — Seso is a labor solution for agriculture. We provide support with the entire H-2A process, including the H-2A Visa, recruiting farmworkers, H-2A compliance, and digital worker onboarding.
Vizcom — Vizcom is an Ai-powered creative tool designed for design and creative professionals. It offers a transformative approach to concept drawing, enabling users to turn their sketches into impressive realistic renderings quickly and efficiently.
Nourish — Achieve your desired health and wellness through personalized nutrition counseling. Nourish is the easiest way to find a registered dietitian and get it covered by your insurance. Find a dietitian today and start your telehealth appointments.

Angels4Women is a company that invests in business startups lead by females.

Investment focus

Retail, Fashion, Lingerie
Seed, Angel, Funding Round
Italy, United States

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
FUTURELY — FUTURELY is a platform which will help to choose university.
Chite Milano — Lingerie the Italian way. Discover 100% Made in Italy lingerie. Make your own: customise your lingerie and nightwear.

Launch Tennessee provides startup resources to entrepreneurs, including capital sources, mentorship, accelerators, entrepreneurship training and more

Investment focus

Software, Health Care, Medical
Grant, Seed, Series A
United States, China, Italy

Portfolio highlights

DAXOR — DAXOR Corporation is an innovative medical instrumentation and biotechnology company. DAXOR designed and developed the BVA-100 Blood Volume Analyzer. It is the first instrument approved by the FDA to provide rapid direct measurement of a patient's true blood volume. We believe that the BVA-100 Blood Volume Analyzer has the potential totransform therapy in a broad range of surgical and medical conditions. It is our goal, working in conjunction with hospitals and clinics, to achieve that possibility.The BVA-100 is a semi-automated Blood Volume Analyzer. It is used in conjunction with a single use diagnostic kit. It is the first FDA-approved instrument to provide rapid direct measurement of a patient's blood volume.
Preteckt — Preteckt's AI software predicts & prevents breakdowns in buses & coaches. Reduce costs, maximize uptime, & extend vehicle life
Branch Technology — Patented 3D-printed fabrication technology combining additive manufacturing, prefabrication, and digital technology at construction scale, with true design freedom.

Embed Capital directly invests in startups, established or in the process of creation.Embed is mainly focused on innovative companies that:- Are active in the so-called “real economy” sectors: industrials, technology, environment, services, retail or social;- Are characterized by simple and intuitive business models and valuepropositions, and operate in markets or market segments featuring high growth potential;- Present a clear competitive advantage and high barriers-to-entry;- Are cash-generative in the medium term.Given that Embed Capital is not a closed-end fund, it doesn’t have specific time-constrains and it can assess on a project-by-project basis to determine the best time to sell a participation, and sign customized agreements with the entrepreneurs.

Investment focus

Information Technology, Health Care, Mobile
Seed, Funding Round, Pre-Seed
Italy, Switzerland, United Kingdom

Portfolio highlights

Piantando — Piantando sells plants connected to initiatives for the preservation of the planet engaged in the following areas: land, water, climate, biodiversity and local communities. Each plant is equivalent to a transparent and unique contribution, destined to an initiative certified by our Value Chain. Everyone become ambassadors of a new way of livinggreen and understanding their commitment to the planet.
FrescoFrigo - Healthy food close to you — FrescoFRIGO is a smart fridge with fresh and quality products designed for the needs of worker. Improve everyday lifestyle, through automated proximity selling of good, fresh and healthy product, innovating technology and user experience.
The Nemesis — The Nemesis is the Metaverse for the mass market: virtual worlds, adventures, gaming Play & Earn and amazing experiences.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Triveni Bio — Triveni Bio is pioneering a genetics-informed precision medicine approach to develop functional antibodies to treat immunological and inflammatory disorders.
Remix Therapeutics — Remix Therapeutics is a biotechnology company that develops novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.
Accent Therapeutics — Accent Therapeutics is a biopharmaceutical company developing oncology-focused, small molecule therapies in the emerging field of epitranscriptomics. This field of biology encompasses post-transcriptional chemical modifications of RNA that provide cells with a unique mechanism for regulating proteins critical for cellular growth anddifferentiation. By targeting cancer-linked RNA-modifying proteins (RMPs) with precision therapies, they aim to translate extraordinary science into life-changing therapies for patients.

European Circular Bioeconomy Fund invest and partner with entrepreneurs to accelerate late-stage circular bioeconomy companies.

Investment focus

Biotechnology, AgTech, Agriculture
Series B, Series A, Series C
The Netherlands, France, Belgium

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
watttron — Watttron invents a revolutionary heating system that can heat up surfaces heterogeneously.Watttron develops an innovative heating technology that can be used in various industrial processes. It is superior to current heating systems in many ways and offers a number of advantages. On the following pages, you will find information about possibleapplications and opportunities.The company is located in the Technologie- und Gründerzentrum Freital – a technology and start-up center on the outskirts of Dresden, the state capital of Saxony.
RED Horticulture — RED Horticulture specializes in horticulture LED lighting systems, photobiology research, and indoor and greenhouse lighting.

RECOMEC operates as a venture capital firm that primarily invests in the healthcare sector.

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

Enrico Pandian is the Co-Founder and CEO of StartupGym and the Founder of FrescoFrigo. He previously worked at Checkout Technologies as a Co-Founder and President of the Board. Enrico Pandian attended the University of Verona.

Investment focus

E-Commerce, SaaS, Pharmaceutical
Seed, Angel, Pre-Seed
Italy, United States

Portfolio highlights

Quisto — On Quisto, Ho.Re.Ca. retailers can find the best suppliers in their area and purchase 24/7 whatever they need for their business --> www.quisto.it
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Viceversa — Viceversa provides capital to European digital businesses to support companies in sustainable and ethical growth. The company was founded in 2021 and has locations in Milan and Dublin.

Riso Gallo is a rice producer specializing in processing, and distributing of risotto rice to consumers around the world.

Investment focus

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.

Istituto Nazionale Biostrutture e Biosistemi is a platform for biostructures and biosystems that represent the intersection and the synthesis between the life sciences and physical sciences.

Investment focus

Wellness, Health Care, Biotechnology
Corporate Round
Italy

Portfolio highlights

Adamas Biotech — More than a decade of basic research in the field of botanical function-specific antioxidants. The nutraceutical solutions proposed to stem from a patented protected technology.

Kering Ventures is the venture investment arm of the Kering Group, acquiring minority holdings in startups.

Investment focus

Biotechnology, Interior Design
Series A
Italy

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.

Schia Ventures is investment firm.

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

Intesa Sanpaolo is a banking group that specializes in wealth management, protection, advisory, and digital orientation. Their products and services include accounts, cards, loans, mortgages, insurance, digital payments, retirement planning, investments, and consulting.

Investment focus

Financial Services, FinTech, Renewable Energy
Debt Financing, Post-IPO Debt, Series A
Italy, United Kingdom, United States

Portfolio highlights

Soplaya — Ordina in un click e ricevi nel tuo ristorante in 12/48h, migliaia di ingredienti direttamente dal produttore. Consegna sempre gratuita
Sendabox — Sendabox.it is the first online express courier rate comparison. With sendabox.it compare and ship at unbeatable prices without leaving home. Thanks to the innovative private platform, SMEs, e-commerce and freelancers can save money by simplifying processes and optimizing their business.
Vena Energy — Vena Energy is a leading Independent Power Producer (IPP) and an integrated pure-renewable energy company in the Asia-Pacific region.

The official website of the European Commission, providing access to information about its political priorities, policies and services

Investment focus

Software, Health Care, Biotechnology
Grant, Seed, Pre-Seed
Spain, France, United States

Portfolio highlights

Kikleo — Kikleo provides smart solutions for monitoring the food waste in restaurants and collects and analyzes the data to implement solutions.
Elcogen — Elcogen is a manufacturer and developer of high-performance anode-supported Intermediate Temperature Solid Oxide Fuel Cells (IT-SOFC) and SOFC stacks based on proprietary materials and technological solutions. Fuel cells will help enable a clean energy future. Fuel cell technology significantly reduces emissions from natural gas systems,delivering twice the power for the same amount of gas. Fuel cells also unlock greater renewable energy generation, converting electricity to hydrogen for long-term storage. Solid oxide fuel cells are the most efficient energy conversion method possible, and Elcogen manufactures the highest performing SOFC. Elcogen makes the fuel cell technology underpinning the clean energy systems of the future.Elcogen was established in 2001.
AlgoWatt — algoWatt designs, develops and integrates solutions for the management of energy and natural resources , in a sustainable and socially responsible way , guaranteeing a competitive advantage. The Company provides management and control systems that integrate devices, networks, software and services with a clear sectoral focus: digital energy andutilities , smart cities & enterprises and green mobility .algoWatt was born from the merger of TerniEnergia, a leading company in the renewable energy and environmental industry, and Softeco, an IT solution provider with over 40 years of experience for customers operating in the energy, industry sectors and transportation.

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