Top 10 CleanTech Startup Investors in Italy in April 2025

Last updated: Apr 2025 A list of 10 angel investors and VC (Venture Capital) funds that invest in Cleantech startups based in Italy. We rank investors based on the number of investments they made in Cleantech companies from Italy. We update this investor list every month.

Top 10 CleanTech Startup Investors in Italy in April 2025

Investor	CleanTech Italy investments
Cassa Depositi e Prestiti	6
CDP Venture Capital	4
Stefano Mezzadri	1
LIFTT	1
Key Capital	1
Club degli Investitori	1
Novum Capital Partners	1
Lazio Innova	1
Eureka Venture	1
A11 Venture	1

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Investor list

The Cassa Depositi e Prestiti Group is the national promotional institution that has supported the Italian economy since 1850

Investment focus

Health Care, Manufacturing, CleanTech
Pre-Seed, Post-IPO Debt, Debt Financing
Italy, Spain

Portfolio highlights

Arxax — Arxax is a cleantech company paving the way towards a more sustainable future by revolutionizing refueling in road transport.Through our passion for a cleaner, greener world we have developed a smart network of green refueling stations powered by our proprietary suite of connected technology solutions. Our suite of products uses data signalsfrom existing IoT hardware devices such as truck telematics, sensors, Outdoor Payment Terminals and smartphones to bring access to low and zero carbon fuels at optimally located refuelling stations, competitive pricing and full refuelling visibility to our customers.
MrCall — Un assistente digitale dedicato al tuo business, che risponde quando non puoi, raccoglie i messaggi e li trascrive in una mail, un SMS o un messaggio Whatsapp.Configurabile e attivo sul telefono in due passaggi. Senza cambiare operatore, senza installare nuovi software, senza nuovi centralini.Nessun investimento o costo di attivazionerichiesto.
TimeFlow — TimeFlow is a software that acts as a B2B marketplace dedicated to the technical and managerial consulting sector.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Funding Round
Italy, United States, Germany

Portfolio highlights

Mopso — Discover Mopso's anti money laundering detection system. Visit our website and try a 30 minutes free demo with one of our experts.
Postura Ergonomics — Postura transform workers videos into ergonomic risk assessments for manufacturing companies. Our AI delivers quick, accurate, and scalable analyses, cutting costs and compliance time. ergonomia lavoro ufficio
Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Stefano Mezzadri

Investment focus

Events, Battery, CleanTech
Pre-Seed
Italy, Denmark

Portfolio highlights

Tame — ABOUT With Tame you can fully customise your virtual events, and make them fun, engaging & exciting to attend.- Apply your branding: Customise your virtual event completely - Personalised Welcome: Personal welcome message when attendees enter - Multiple stages: Broadcast content across multiple stages. - Live streaming: Stream live via anybroadcasting software - Pre-recorded videos: Broadcast pre-recorded videos as if it was live - Breakout sessions: Enable public or private breakout sessions. - Virtual Sponsor booths: Allow attendees to engage with sponsors live. - Customise Chat: Allow for 1:1 chat, group chat or session chat. - 1:1 Video Meetings: Empower social networking virtually.OUR COMPANY We are an experience-centric company, and we believe in the power of great experiences.   Our international group of dreamers, creators and rule-breakers passionate about merging design and technology together, enables us to transform that into one truly amazing event platform.OUR PEOPLE The team behind Tame has an aggregated decades long experience of creating events and building products that solve real problems for real people. So, what got us here? Our ambition to change a broken event industry through innovation, customer obsession and a relentless focus on the great experience.
Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Biotechnology, Software, Information Technology
Seed, Funding Round, Series A
Italy, United Kingdom, France

Portfolio highlights

Mediaire — mediaire supports radiologists with AI-based tools for MRI reporting. This enables them to make a more accurate and objective assessment even faster.
MicroLub — MicroLub produces a fat replacement for lower-calorie plant-based diets. It is cutting-edge innovation to the next generation of protein technology, creating exclusive ingredient solutions that significantly minimize molecular friction.
Composite Research — CoRe Research is an start-up, aimed at the study of new product and process solutions in the field of composite materials.

We are a venture incubator that wants to exploit the extraordinary human capital of the new digital entrepreneurship. From design to ready-to-market, up looking for new partners and capital, we create value along the entire continuum of mentoring: direct investment , skills qualified and specialized network support the growth of new businesses oftomorrow. With our deal flow , we are able to select innovative ideas with high potential with a business model that minimizes the investment risk and guarantee the success on the market.

Investment focus

Internet, Apps, E-Commerce
Seed, Pre-Seed, Series A
Italy, United States, Philippines

Portfolio highlights

Pixies — Pixies is a Startup that design solutions for Autonomous Cities and a more sustainable future of our planet. Merging Urban Design, Robotics and AI, we believe that urban spaces can now become able to take care of themselves.
Alokino Gelato — Alokino Gelato produces plant-based and preservative-less artisanal ice creams.
Wopta Assicurazioni — Wopta Assicurazioni is the first Italian phygital insurtech which, thanks to a digital platform and a network of tied specialist throughout the country, was created to protect artisans, SMEs and freelances from everyday risks.

Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.

Investment focus

Health Care, E-Commerce, Information Technology
Seed, Series A, Series B
Italy, Switzerland, United Kingdom

Portfolio highlights

Stema — It serves as a platform for hiring engineers
Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation
Lymphatica Medtech — Lymphatica Medtech is a medical device development company developing a minimally invasive solution for chronic lymphedema.Lymphedema is the chronic swelling that generally occurs in the arms or the legs.Lymphedema is most commonly caused by the removal of or the damage to the lymph nodes as a part of cancer treatment. It results from ablockage in the lymphatic system, which is part of the immune system. The blockage prevents the lymphatic system from draining excess fluids, and the fluid buildup leads to swelling, infections, and pain.Unfortunately, there is no cure for lymphedema. It can be managed with early diagnosis and diligent care of the affected limb, through daily compression, bandages, and manual drainage sessions. From the moment of the diagnosis, the life of lymphedema patients changes forever.Cancer and cancer-related interventions (i.e. surgery, radiotherapy) are frequent causes of lymphedema occurring both in the upper and lower limbs. Breast cancer survivors are at high risk for developing lymphedema, as well as patients treated for melanoma, pelvic and head and neck cancer or other cancer treatments that require lymph node dissection. Physical trauma can also result in lymphedema, a major cause of lymphatic disease among wounded veterans.Lymphedema is associated with significantly impaired quality of life, skin changes, increased risk of infection and in rare cases lymphedema itself may undergo malignant transformation.Lymphatica offers a permanent solution that will allow patients to regain their normal lifestyle.

Novum Capital Partners is a Swiss multi-family office.

Investment focus

Energy, CleanTech, Smart Cities
Seed, Series B
Italy

Portfolio highlights

Wiseair — Wiseair's mission is to enable everyone in the world to breathe clean air. We believe that a problem you can't measure is a problem you can't solve, so we work to enable municipalities, citizens and businesses to measure and learn about air quality, creating actionable, solution-oriented data and information, and generatingawareness.
Energy Dome — Energy Dome | Groundbreaking Long Duration Energy Storage. Using CO2 against climate change. Our Technology enables to store renewable energy efficiently.

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments

Investment focus

Nanotechnology, Renewable Energy, Medical Device
Funding Round, Seed, Pre-Seed
Italy

Portfolio highlights

Planckian — Charging the future by powering energy with science We explore frontiers of energy science by developing quantum...
INTA Systems — Nanotech and artificial intelligence for biomolecular analysis
BeDimensional — New Material Solution

A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi: scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.