Top 10 CleanTech Startup Investors in Italy in May 2025
A list of 10 angel investors and VC (Venture Capital) funds that invest in Cleantech startups based in Italy. We rank investors based on the number of investments they made in Cleantech companies from Italy. We update this investor list every month.Top 10 CleanTech Startup Investors in Italy in May 2025
Investor | CleanTech Italy investments |
---|---|
Cassa Depositi e Prestiti | 6 |
CDP Venture Capital | 4 |
LIFTT | 1 |
Club degli Investitori | 1 |
Novum Capital Partners | 1 |
EUREKA! Venture SGR | 1 |
A11 Venture | 1 |
Lazio Innova | 1 |
Key Capital | 1 |
Stefano Mezzadri | 1 |
The Cassa Depositi e Prestiti Group is the national promotional institution that has supported the Italian economy since 1850
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Investment focus
- Health Care, Manufacturing, CleanTech
- Pre-Seed, Post-IPO Debt, Debt Financing
- Italy, Spain
Portfolio highlights
- BKN301 — Scopri tutti i servizi dedicati a privati, aziende ed esercenti. Accedi all'area riservata.
- NextChem — NextChem is the green chemistry subsidiary of Maire Tecnimont, an Italian multinational company specializing in engineering, technology, and energy. NextChem focuses on the energy transition by developing and deploying innovative solutions for sustainable industrial processes. It aims to accelerate decarbonization and promote the circular economythrough advanced technologies.
- TimeFlow — TimeFlow is a software that acts as a B2B marketplace dedicated to the technical and managerial consulting sector.
CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.
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Investment focus
- Software, Health Care, Information Technology
- Seed, Series A, Funding Round
- Italy, United States, United Kingdom
Portfolio highlights
- Tundr — Tundr offers smartcard to companies for sustainable mobility.
- Genius4U — Genius4U offers washing, sewing, registered mail, shipping, and parcel delivery services. They provide physiotherapist massager, osteopath, nutritionist, hairdresser, beautician, and psychologist services. They also provide professional babysitting services.
- Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.
A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.
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Investment focus
- Biotechnology, Software, Information Technology
- Seed, Funding Round, Series A
- Italy, United Kingdom, France
Portfolio highlights
- Lumai — Lumai delivers fully optical computing for a quicker, smarter and more sustainable world. Lumai power the revolution of fully optical computing by working at the nexus of photonics and machine learning.
- Mediaire — mediaire supports radiologists with AI-based tools for MRI reporting. This enables them to make a more accurate and objective assessment even faster.
- Sparrow Quantum — Sparrow Quantum, a global leader in quantum photonic chip technology. Explore innovative solutions driving advancements in quantum computing, communication, and beyond. Stay ahead with cutting-edge technologies shaping the future.
Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.
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Investment focus
- Health Care, E-Commerce, Information Technology
- Seed, Series A, Series B
- Italy, Switzerland, United Kingdom
Portfolio highlights
- Stema — It serves as a platform for hiring engineers
- Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation
- Lymphatica Medtech — Lymphatica Medtech is a medical device development company developing a minimally invasive solution for chronic lymphedema.Lymphedema is the chronic swelling that generally occurs in the arms or the legs.Lymphedema is most commonly caused by the removal of or the damage to the lymph nodes as a part of cancer treatment. It results from ablockage in the lymphatic system, which is part of the immune system. The blockage prevents the lymphatic system from draining excess fluids, and the fluid buildup leads to swelling, infections, and pain.Unfortunately, there is no cure for lymphedema. It can be managed with early diagnosis and diligent care of the affected limb, through daily compression, bandages, and manual drainage sessions. From the moment of the diagnosis, the life of lymphedema patients changes forever.Cancer and cancer-related interventions (i.e. surgery, radiotherapy) are frequent causes of lymphedema occurring both in the upper and lower limbs. Breast cancer survivors are at high risk for developing lymphedema, as well as patients treated for melanoma, pelvic and head and neck cancer or other cancer treatments that require lymph node dissection. Physical trauma can also result in lymphedema, a major cause of lymphatic disease among wounded veterans.Lymphedema is associated with significantly impaired quality of life, skin changes, increased risk of infection and in rare cases lymphedema itself may undergo malignant transformation.Lymphatica offers a permanent solution that will allow patients to regain their normal lifestyle.
Novum Capital Partners is a Swiss multi-family office.
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Investment focus
- Energy, CleanTech, Smart Cities
- Seed, Series B
- Italy
Portfolio highlights
- Wiseair — Wiseair's mission is to enable everyone in the world to breathe clean air. We believe that a problem you can't measure is a problem you can't solve, so we work to enable municipalities, citizens and businesses to measure and learn about air quality, creating actionable, solution-oriented data and information, and generatingawareness.
- Energy Dome — Energy Dome | Groundbreaking Long Duration Energy Storage. Using CO2 against climate change. Our Technology enables to store renewable energy efficiently.
Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments
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Investment focus
- Nanotechnology, Renewable Energy, Medical Device
- Seed, Funding Round, Pre-Seed
- Italy
Portfolio highlights
- Novac — Progettiamo supercondensatori da affiancare alle batterie, per incrementare performance ed efficienza dei veicoli elettrici.
- WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.
- BeDimensional — New Material Solution
A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi:
scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.
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Investment focus
- Biotechnology, Medical Device, Health Care
- Seed, Pre-Seed, Series A
- Italy, United States
Portfolio highlights
- Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
- Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
- Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.
Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.
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Investment focus
- Software, Health Care, Artificial Intelligence
- Seed, Pre-Seed, Grant
- Italy, United Kingdom
Portfolio highlights
We are a venture incubator that wants to exploit the extraordinary human capital of the new digital entrepreneurship. From design to ready-to-market, up looking for new partners and capital, we create value along the entire continuum of mentoring: direct investment , skills qualified and specialized network support the growth of new businesses oftomorrow. With our deal flow , we are able to select innovative ideas with high potential with a business model that minimizes the investment risk and guarantee the success on the market.
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Investment focus
- Internet, Apps, E-Commerce
- Seed, Pre-Seed, Series A
- Italy, United States, Philippines
Portfolio highlights
- Pixies — Pixies is a Startup that design solutions for Autonomous Cities and a more sustainable future of our planet. Merging Urban Design, Robotics and AI, we believe that urban spaces can now become able to take care of themselves.
- Alokino Gelato — Alokino Gelato produces plant-based and preservative-less artisanal ice creams.
- Wopta Assicurazioni — Wopta Assicurazioni is the first Italian phygital insurtech which, thanks to a digital platform and a network of tied specialist throughout the country, was created to protect artisans, SMEs and freelances from everyday risks.
Stefano Mezzadri
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Investment focus
- Events, Battery, CleanTech
- Pre-Seed
- Italy, Denmark
Portfolio highlights
- Tame — ABOUT With Tame you can fully customise your virtual events, and make them fun, engaging & exciting to attend.- Apply your branding: Customise your virtual event completely - Personalised Welcome: Personal welcome message when attendees enter - Multiple stages: Broadcast content across multiple stages. - Live streaming: Stream live via anybroadcasting software - Pre-recorded videos: Broadcast pre-recorded videos as if it was live - Breakout sessions: Enable public or private breakout sessions. - Virtual Sponsor booths: Allow attendees to engage with sponsors live. - Customise Chat: Allow for 1:1 chat, group chat or session chat. - 1:1 Video Meetings: Empower social networking virtually.OUR COMPANY We are an experience-centric company, and we believe in the power of great experiences. Our international group of dreamers, creators and rule-breakers passionate about merging design and technology together, enables us to transform that into one truly amazing event platform.OUR PEOPLE The team behind Tame has an aggregated decades long experience of creating events and building products that solve real problems for real people. So, what got us here? Our ambition to change a broken event industry through innovation, customer obsession and a relentless focus on the great experience.
- Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
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