Top 50 Health Care Startup Investors in Italy in May 2026

Portfolio highlights

• ALBA Robot — Through our micro mobility platform we add autonomy and artificial intelligence to transform passengers transportation.
• RARA Factory — RARA Factory is a company that provides research and development of sustainable materials utilizing physics-based artificial intelligence.
• Proxima Fusion — We are a European fusion energy startup pursuing the clearest path to grid deployment.

Portfolio highlights

• Stema — It serves as a platform for hiring engineers
• Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation
• Annaida Technologies — Empowering fertility providers and researchers with AI-driven metabolomic platforms. Non-invasive, real-time insights at the microscale for personalized medical treatments.

Portfolio highlights

• ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
• Rubedo Life Sciences — Rubedo Life Sciences is the Premier Longevity Company. Rubedo discovers and develops medicines to keep you biologically young.
• Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

Portfolio highlights

• NodThera — NodThera is a biotechnology company treating chronic diseases by targeting inflammation at its source.
• Biosyntia — Biosyntia is a biotech startup within synthetic biology and metabolic engineering. We develop biocatalysts at an unprecedented speed and efficiency by employing our patent pending high-throughput screening technology.By developing tailored processes based on biocatalysis, Biosyntia enables production of complex chemical compounds byfermentation. Biocatalysis may substantially reduce both production costs and environmental impact compared to other processes such as chemical synthesis. We partner with manufacturers of fine chemical compounds (flavors, fragrances, APIs, pigments, additives, intermediates, and more) in order to establish more sustainable manufacturing processes for a greener tomorrow.Biosyntia is located at the Novo Nordisk Foundation (NNF) Center for Biosustainability in Hørsholm, 25 kilometers north of Copenhagen.
• T-Therapeutics — T-Therapeutics is a expertise in mouse genome engineering, deep expertise in biopharmaceutical drug development, single cell genomics, machine-learning and structural biology, anchored in a culture of creativity and collaboration. .

Portfolio highlights

• DeepUll — DeepUll is a biotech company that focuses its activity on the development of a new diagnostic system for early-stage sepsis condition. DeepUll’s proposal is based on quickly identifying the pathogens and offering the antibiogram within a few hours on the one hand, and on using the data and learning about the patient’s immunological and functionalstatus on the other. The system allows doctors to predict the future appearance and evolution of sepsis within a short period of time and thus provide a suitable clinical response even before the symptoms arise.
• Salvia BioElectronics — Our mission is to give people with migraine a better life. As a pioneer in the field of medical devices, Salvia BioElectronics is passionately committed to empowering people with migraine to reclaim their lives.
• Endovascular Engineering — Endovascular Engineering is a preclinical stage company developing novel mechanical thrombectomy solutions to address peripheral indications.

Portfolio highlights

• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• CamGraPhIC — Our platform supports the ever-increasing data traffic demand with high-performing and low-power consumption electro-optical engines.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Therapeutics develops innovative targeted cancer therapy solutions using its proprietary YntraDose technology for nuclear medicine.

Portfolio highlights

• QSensAto — QSensAto is a quantum sensing company specializing in the development and research of integrated vapor cells and quantum atomic sensors.
• Agate Sensors — Agate Sensors offers equipment manufacturers advanced sensors that detect, identify, and classify people, vital signs, objects, and more. Their sensors come in a range of sizes, from single pixel devices to full matrix devices, and are produced using standard CMOS production processes, making them both cost-effective and efficient.
• Sparrow Quantum — Sparrow Quantum, a global leader in quantum photonic chip technology. Explore innovative solutions driving advancements in quantum computing, communication, and beyond. Stay ahead with cutting-edge technologies shaping the future.

Portfolio highlights

• KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• Tuidi — Tuidi is a tech startup that develops predictive models of AI, with a particular focus on the food distribution sector. They combine methodical study of data, personalization of business processes and speed of integration for to return an output that is not only accurate but also free from interpretation difficulties so as to increase profits,reduce stock outages and optimize inventories.
• Titan4 — Titan4 provides products and services based on research combining different satellite data and sources for applications. They also provide development and integration, InSAR data analysis and data mining, geological analysis, and deep learning analytic services.
• Live Story Inc. — The no-code frontend creative platform for enterprise digital, e-commerce and marketing teams. Design, publish and personalise digital experiences. Design to market with no developer queue and no compromises on governance.

Portfolio highlights

• Piantando — Piantando sells plants connected to initiatives for the preservation of the planet engaged in the following areas: land, water, climate, biodiversity and local communities. Each plant is equivalent to a transparent and unique contribution, destined to an initiative certified by our Value Chain. Everyone become ambassadors of a new way of livinggreen and understanding their commitment to the planet.
• FrescoFrigo - Healthy food close to you — FrescoFRIGO is a smart fridge with fresh and quality products designed for the needs of worker. Improve everyday lifestyle, through automated proximity selling of good, fresh and healthy product, innovating technology and user experience.
• The Nemesis — The Nemesis is the playground for play-to-earn games and adventures in virtual worlds. Accessible on both mobile and desktop.

Portfolio highlights

• PatchAi — Improve patient engagement and experience in clinical trials and standard care. Discover Patchai solution.
• 1000Farmacie — 1000Farmacie is the leading Pharmacy Marketplace in Italy. Though a network of independent Pharmacies we deliver faster!
• YourCoach Health — Health and Wellness coach practice management solution enabling coaches to holistically lead their clients, connecting mind, body and soul through behavior modification and accountability tools towards outcomes

Portfolio highlights

• NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
• ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
• Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
• Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Portfolio highlights

• Loquis — La prima piattaforma per ascoltare e raccontare il mondo tramite podcast geolocalizzati
• Intron Health — Voice AI Built for How Africa Speaks Our next-generation intelligent voice model built from the ground up for AfricaUnlike Global systems retrofitted for the continent Sahara v-2 understands how Africa actually sounds Build with Sahara Try Sahara Built for African SpeechFrom Lagos Call Centers, to Hospitals in Nairobi, Boardrooms in Cape Town, and Courtrooms in
• Cyberwave — Transform your industry with AI-defined robotics. Frictionless automation that makes advanced robotics accessible to manufacturers of all sizes.

Portfolio highlights

• Biovitae — Benvenuto sul sito ufficiale di Biovitae, la tecnologia italiana brevettata per la sanificazione degli ambienti.
• VR Media Srl — Kiber is a hands-free remote assistance and inspection platform for industry. Capture visual data, collaborate remotely and generate structured real-time reports.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
• CaSRevolution — A novel disease-modifying approach against neurodegeneration
• Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Portfolio highlights

• PlantBit — PlantBit is a producer of sensors and services for smart farming.
• LOTO Biotech — LOTO Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations.
• LayerLogic AB — Reliable and instantaneous bacteria detection

Portfolio highlights

• Caracol — Lead the future of manufacturing thanks to Caracol's 3D printing technologies. Discover our solutions for industrial, Large Format Additive Manufacturing.
• FLEEPtech — FLEEP Technologies designs and develops printed electronics solutions for the biomedical and smart packaging sectors. The company, spin-off of Istituto Italiano di Tecnologia, was founded in May 2019.FLEEPtech developed a proprietary process for the fabrication of polymer-based integrated circuits based on Organic Thin-Film Transistors, creatingthe intelligent core for electronics systems that are mechanically flexible, printed like magazines and recyclable. FLEEPtech is the missing link in the printed electronics industry between a great number of flexible and printed products (i.e. sensors, actuators and energy supplies) that find little space in being integrated with standard non-flexible electronics. For such reasons, the company's mission revolves around the realization of a general purpose platform for the manufacturing of fully-printed integrated systems, composed by printed sensors, printed actuators, printed energy supplies and harvesters and, of course, printed integrated circuits.
• INTA Systems — Nanotech and artificial intelligence for biomolecular analysis

Portfolio highlights

• Therini Bio — Therini Bio is developing novel therapeutics based insights into the role of fibrin in driving chronic innate immune activation.
• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Avation Medical — 42 million men and women have symptoms of OAB and incontinence. Vivally can help.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
• Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

Portfolio highlights

• UNGUESS (formerly AppQuality) — UNGUESS is the crowdsourcing platform for effective testing and real insights. Take the guesswork out of your work.
• Paragraph — Powerful stories and powerful storytellers. Each week find seven of the world's best shorts in text, audio, and video: http://bit.ly/1usXQd5
• La Passione — High quality Italian Road and Urban cycling wear at fair prices. We use only the finest materials and sell direct to you with no middleman. Shop now!

Portfolio highlights

• MMI — The future of Microsurgery: microinstruments that expand the possibilities of surgical interventions. Wristed robotic microinstruments for unprecedented results in microsurgery.
• Tubulis — Reimagining Antibody Drug Conjugates Tubulis generates uniquely matched protein-drug conjugates through the combination of novel proprietary technologies and disease-specific biologic insight. Our goal is to expand the therapeutic potential of antibody-drug conjugates (ADCs) by increasing design flexibility while overcoming constraints of toxicity, efficacy and indication. Tubulis will build new conjugates to fill its pipeline and
• Mineralys Therapeutics — Evolving science is revealing the importance of aldosterone in cardio-renal-metabolic diseases.We are focused on improving outcomes for people managing hypertension, CKD and related diseases that are driven by dysregulated aldosterone. About Aldosterone

Portfolio highlights

• GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
• ALLSIDES — Covision Media specializes in creating high-quality, relightable 3D models using their industrial 3D scanners. These scanners capture detailed surface information and PBR textures, and are designed for easy integration into virtual environments.
• Cyberwave — Transform your industry with AI-defined robotics. Frictionless automation that makes advanced robotics accessible to manufacturers of all sizes.

Portfolio highlights

• Toduba — Toduba is a digitalization company that provides shopping vouchers, food stamps, gift cards, and travel expense management.
• Hotiday — Hotiday is the first hospitality startup that applies Instant Buying to the hotel industry to become a true "Online-Only" hotel chain, completely decentralized
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.

Portfolio highlights

• D-Orbit — End-to-end services for the New Space industry, including platform engineering, launch and deployment, and decommissioning.
• Bricks.sh — The fastest way to build and manage your Supabase database. One-click admin panel with powerful features for teams.
• RARA Factory — RARA Factory is a company that provides research and development of sustainable materials utilizing physics-based artificial intelligence.

Portfolio highlights

• Eden Bio — Eden Bio is a biotech using machine learning to guide the genetic engineering of microorganism strain optimisation, improving protein yield.
• Golden — Golden is a developer of a self-constructing knowledge database used to accelerate discovery and education. The company uses and leverages human effort by using machine intelligence to make the process of gathering and communicating knowledge simpler.It combines a powerful search across several entities with fine-grain alerts to stay on top ofchanges, and semi-automatic research assistance for gaps in knowledge that enable people in organizations to stay current, understand and leverage the latest trends in their industry.
• Kresko Labs — Join the Quest for accessible wealth with Kresko, a synthetic asset protocol. Explore innovative possibilities now.

Portfolio highlights

• MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
• Yoyomove — Yoyomove is a long-term car rental company that offers long-term vehicle rental and flexible mobility solutions designed to simplify your everyday journeys
• Displaid — Displaid abilita la manutenzione predittiva condition-based di tutti i ponti della rete infrastrutturale grazie ad una soluzione di monitoraggio standardizzata, scalabile, e completamente integrata.

Portfolio highlights

• Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
• Biome Analytics — Biome is an analytic applications that help cardiovascular teams do their best work. It helps forward thinking hospitals profitably transition and thrive in the new world of healthcare. During COVID-19, Biome has focused on assessing hospital capacity.
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.

Portfolio highlights

• AWorld — AWorld is The Sustainability Platform and Mobile App chosen by the United Nations to support the ActNow Campaign.
• Medics — 3D anatomical modeling per la pianificazione pre-operatoria e il supporto intra-operatorio delle chirurgie complesse.
• Faccin Group — Faccin Group leads in manufacturing top tier metal forming & bending machines. Operating as Faccin, Roundo & Boldrini, we offer unparalleled expertise.

Portfolio highlights

• Reap — Reap helps you pay expenses using a credit card, collect payments from around the world, and improve your expense and cash flow management. All in one platform.
• Glints — Explore internships, graduate jobs & career development resources on Glints. Do what you love on our career discovery & development platform.
• Tangia — Tangia is an all in one platform that allows content creators to supercharge their viewer engagement, boost income, and unleash viewer creativity

Portfolio highlights

• SurgiQ — SurgiQ strives to make surgical pathways more effective, less invasive and easier on surgeons, patients, and their families. We help healthcare providers being more efficient and deliver timely care by providing an innovative audit and planning platform supported by AI algorithms.
• Tossed — Healthy eating doesn't have to be boring with our delicious hot pots, house salads, power bowls & rainbow wraps made with fresh vegetables, lean protein & low GI carbs.
• AirHelp — AirHelp is an online legal service that helps air passengers get compensation from airlines when their flight gets canceled, delayed, or overbooked. Passengers can access the service via its official Facebook page or its mobile app available for iOS and Android devices.AirHelp takes care of all the paperwork and legal communications with theairline on behalf of the passengers and claims 25% of the compensation obtained as its service fee. The compensation amount varies between $170 to $650 based on the distance flown by the flight and the duration of the delay experienced by the passenger at the final destination.AirHelp was launched in 2013 by Greg Roodt, Henrik Zillmer, and Nicolas Michaelsen.

Portfolio highlights

• Noiet — Noiet is a biotechnology firm whose mission is to develop clean, natural, and fermented proteins that serve as multifunctional alternatives.
• Feralpi Group — Feralpi Group is a steel manufacturer that specializes in the production of construction steels, responsibility, safety, and innovation.
• E4 Computer Engineering — E4 Computer Engineering stands out for its tireless pursuit of the most cutting edge proposals in the IT sector.

Portfolio highlights

• GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
• Insoore — Insoore is a platform that helps insurance companies to improve the claims management process, thanks to on-demand photographic inspections and damage estimates provided by a community of experts.
• Carol — Carol is a tech-enabled healthcare provider delivering membership-based primary care services, on a mission to make high-quality healthcare accessible and affordable for everyone. To achieve this goal, Carol leverages a highly scalable technology, combined with high quality clinical operations and a salaried provider model.

Portfolio highlights

• Talyn Air — Inspired by two-stage rockets, our innovative eVTOL uses two flight vehicles to transform flight. Fixed-wing performance with VTOL capabilities.
• BillionToOne — We are a team at the forefront of disease detection focused on moving Prenatal Screening and Liquid Biopsy forward.
• CaSRevolution — A novel disease-modifying approach against neurodegeneration

Portfolio highlights

• EarlySight — EarlySight start-up company is founded in order to accelerate the development and to bring the technology to clinics.
• BeDimensional — New Material Solution
• Magentiq Eye Ltd — AI assisted colonoscopy by MAGENTIQ EYE set a new standard of , recognized by the gastroenterology community for its superior performance.

Portfolio highlights

• BonusX — Con l'app BonusX hai un supporto anti-burocrazia tutto l'anno. Accedi a centinaia di bonus e servizi pubblici, senza stress e code.
• WithLess — Apps multiply, costs grow, admin spirals. We get it. The tools your team needs WithLess time, money, and admin.
• Vivaio Ventures — Vivaio Ventures partners with early-stage and creator-led consumer brands to scale food, beverage, and beauty products. We offer capital, consulting, and Made in Italy manufacturing excellence for the next CPG leaders.

Portfolio highlights

• NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
• Fore Biotherapeutics — We are a precision oncology company pioneering the development of cancer therapies guided by our proprietary functional genomics.
• On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

Portfolio highlights

• Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
• Maticmind S.p.A — Maticmind S.p.A is a company that provides ICT and system integration solutions to telecommunications operators.
• Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Portfolio highlights

• Gamindo — Create interactive training experiences in minutes with AI and gamification. Increase engagement, completion rates and learning outcomes.
• Lampoo — Consign your luxury items and earn up to 80% of the sale! Shop authenticated designer brands at second hand prices! Fast deliveries and easy returns!
• This Unique — Customize your own period with a unique assortment to fit your needs that's sustainable and committed.

Portfolio highlights

• Tuduu — Tuduu.it: Revolutionizing the Internationalization of Italian Food E-commerceTuduu.it is an innovative internationalization-as-a-service platform designed to empower small and medium-sized Italian food producers to overcome the digital and linguistic barriers that limit their global reach. By providing a scalable AI-powered ecosystem, Tuduuenables these producers to seamlessly translate, enrich, and showcase their product catalogs and recipes in over 17 languages, unlocking new export opportunities across Europe and beyond.The Challenge The Italian agri-food sector is a global leader, generating over €523 billion in turnover and employing 3.6 million people. However, only 15% of this turnover currently derives from exports, and just 20% of Italian food companies have an e-commerce presence — often limited to Italian language only. This poor digitalization and language gap create significant competitive disadvantages for many small and medium producers eager to reach international customers.Tuduu’s Solution Tuduu.it addresses these challenges through a comprehensive, AI-driven digital platform designed as an internationalization-as-a-service (IaaS) model for Made in Italy food e-commerce. The key pillars of Tuduu’s solution include:AI-powered catalog and recipe translation: Automatic, scalable translation of product catalogs, recipes, and user-generated content (UGC) videos into 17 languages, including automated dubbing of video content, enabling producers to speak directly to diverse international markets.Personalized user experience: Dynamic nutrition filters allow users to explore products and recipes tailored to their dietary profiles (e.g., vegan, gluten-free, allergies), with AI algorithms that automatically determine macro- and micronutrients, and assess nutritional compatibility with specific dietary restrictions.Seamless marketplace integration: Producers set up or maintain their own e-commerce sites and access Tuduu’s ecosystem by installing a simple plugin or API feed. This approach preserves producers’ autonomy while enabling them to benefit from Tuduu’s unique international visibility and user engagement.Recipe-driven commerce: Tuduu innovates by combining product discovery with rich recipe content, allowing consumers to explore authentic Italian culinary experiences and directly purchase ingredients through integrated shopping lists and seamless checkout flows.SEO and marketing optimization: Tuduu acts as a multilingual media showcase optimized for both Google search and YouTube video discovery, leveraging AI-generated content and influencer marketing networks to boost brand awareness and export sales.Market Opportunity 54,000+ Italian food companies generate approximately €67 billion in export value annually.The total addressable market (TAM) of the Italian agri-food sector is €523 billion, with the serviceable available market (SAM) focused on the digitally mature segment estimated at €12 billion.Tuduu’s projected serviceable obtainable market (SOM) aims to capture €11.4 million in transactions within five years, with a target of more than 800 retailers and 90 million euros in transaction volume.Business Model Tuduu operates primarily on a performance-based affiliation fee of 10% on sales, coupled with a SaaS subscription starting at €99/month for access to advanced platform features. Custom projects and media services (including influencer campaigns) are offered to support brand promotion and growth.The Tuduu Ecosystem and Team The platform is built on three key scalable AI models:Product Model: Analyzes and translates product data with nutritional profiling and cross-contamination detection.Recipe Model: Automates recipe nutrient calculation and compatibility with specific dietary needs.Nutrition Model: Generates personalized nutrition plans and profiles.The Tuduu team combines expertise in food tech, software development, UX design, marketing, and business development, driven by a shared mission to support Italian food producers’ digital transformation and international expansion.Sustainability and Impact Tuduu embraces sustainability not only as a goal but as a driver of growth. By promoting healthier eating habits through nutritionist-guided recipes and improving access to authentic local products, Tuduu aligns with several United Nations Sustainable Development Goals (SDGs). The platform also supports small producers by facilitating their entry into global markets via digital channels, thereby enhancing social and economic sustainability in local communities.Side Project: Tuduu Nutrition Expanding the core technology, Tuduu has developed a complementary SaaS platform for nutritionists called Tuduu Nutrition. This platform enables rapid creation, analysis, and digitization of personalized nutrition plans, integrated into a mobile app for patient compliance and monitoring.Key features of Tuduu Nutrition include:Generation of tailored nutrition profiles and plans based on validated dietary guidelines.Weekly meal planning with integrated recipes from Tuduu’s extensive database.Shared and collaborative shopping lists that automatically sync with partner retailers for easy purchasing.SaaS pricing based on a monthly subscription (€29/month) plus a fee per managed patient (€2.5/month).Tuduu Nutrition leverages the same AI technology and data models as Tuduu.it, creating synergy between food e-commerce and health-oriented nutrition planning.Financial Outlook and Fundraising Tuduu is currently in a growth and fundraising phase, targeting €1,000,000 in capital with investment tickets starting from €5,000. The company projects rapid scaling with increasing revenues from marketplace transactions, media services, and SaaS subscriptions, aiming for over €11 million in revenues by 2029 and expanding its brand network substantially.Summary Tuduu.it is poised to transform the Italian food export landscape by bridging the gap between small producers and international consumers through advanced AI-driven digital tools, an engaging marketplace experience, and a strong commitment to sustainability and nutrition. Alongside its sister platform Tuduu Nutrition, it creates a comprehensive ecosystem that connects producers, consumers, and health professionals in a unique, scalable way.
• Jet HR — Jet HR makes managing people incredibly simple: payroll, benefits, devices, compliance and much more. We re-thought the HR function, removing anything that is cumbersome and simplifying any action on employees. We are funded by the best Italian VCs (Exor Ventures, Italian Founders Fund and 6 more) and by the best Italian founders (founders ofCasavo, Satispay, Scalapay, Bending Spoons, Musixmatch, Talent Garden, Oyster HR, etc).

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• BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

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• Joinrs — Cut the noise. Joinrs uses AI to find the jobs that actually match your skills, experience and preferences. Over 2 million job seekers trust Joinrs.
• Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
• Ticketoo — Compra e vendi biglietti in modo etico su Ticketoo. La piattaforma sicura per transazioni fan-to-fan. Trova i migliori eventi e assicurati il biglietto per i tuoi spettacoli preferiti.

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• MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
• Freedome — Freedome is the leading marketplace for outdoor activities in Italy

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• Euleria Health — Devices and technologies for more accessible and measurable rehabilitation and telerehabilitation at the service of clinics and movement experts, in the clinic and at home.

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• LIV4 — LIV4 a new voice of quality, offers a practical solution to a pressing need creative startup
• Feralpi Group — Feralpi Group is a steel manufacturer that specializes in the production of construction steels, responsibility, safety, and innovation.
• Stormind Games — Stormind Games is the video game studio specialized in the development of intense stories for PC and consoles.

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• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.
• CorFlow Therapeutics AG — CorFlow Therapeutics is a medtech startup that develops proprietary technologies for diagnosis and treatment of microvascular obstructions in heart attack patients. The CorFlow technologies enable interventional cardiologists to diagnose and treat MVO in severe heart attack patients thereby potentially reducing the short- and long-term complicationrates in these patients.

Portfolio highlights

• GLHF — GLHF is a crypto-native game studio founded by industry veterans. The studio is known for its deflationary NFT collection, GLHFers, on the Ethereum mainnet, and for its Gigaverse ROM collection on Abstract.
• Tuduu — Tuduu.it: Revolutionizing the Internationalization of Italian Food E-commerceTuduu.it is an innovative internationalization-as-a-service platform designed to empower small and medium-sized Italian food producers to overcome the digital and linguistic barriers that limit their global reach. By providing a scalable AI-powered ecosystem, Tuduuenables these producers to seamlessly translate, enrich, and showcase their product catalogs and recipes in over 17 languages, unlocking new export opportunities across Europe and beyond.The Challenge The Italian agri-food sector is a global leader, generating over €523 billion in turnover and employing 3.6 million people. However, only 15% of this turnover currently derives from exports, and just 20% of Italian food companies have an e-commerce presence — often limited to Italian language only. This poor digitalization and language gap create significant competitive disadvantages for many small and medium producers eager to reach international customers.Tuduu’s Solution Tuduu.it addresses these challenges through a comprehensive, AI-driven digital platform designed as an internationalization-as-a-service (IaaS) model for Made in Italy food e-commerce. The key pillars of Tuduu’s solution include:AI-powered catalog and recipe translation: Automatic, scalable translation of product catalogs, recipes, and user-generated content (UGC) videos into 17 languages, including automated dubbing of video content, enabling producers to speak directly to diverse international markets.Personalized user experience: Dynamic nutrition filters allow users to explore products and recipes tailored to their dietary profiles (e.g., vegan, gluten-free, allergies), with AI algorithms that automatically determine macro- and micronutrients, and assess nutritional compatibility with specific dietary restrictions.Seamless marketplace integration: Producers set up or maintain their own e-commerce sites and access Tuduu’s ecosystem by installing a simple plugin or API feed. This approach preserves producers’ autonomy while enabling them to benefit from Tuduu’s unique international visibility and user engagement.Recipe-driven commerce: Tuduu innovates by combining product discovery with rich recipe content, allowing consumers to explore authentic Italian culinary experiences and directly purchase ingredients through integrated shopping lists and seamless checkout flows.SEO and marketing optimization: Tuduu acts as a multilingual media showcase optimized for both Google search and YouTube video discovery, leveraging AI-generated content and influencer marketing networks to boost brand awareness and export sales.Market Opportunity 54,000+ Italian food companies generate approximately €67 billion in export value annually.The total addressable market (TAM) of the Italian agri-food sector is €523 billion, with the serviceable available market (SAM) focused on the digitally mature segment estimated at €12 billion.Tuduu’s projected serviceable obtainable market (SOM) aims to capture €11.4 million in transactions within five years, with a target of more than 800 retailers and 90 million euros in transaction volume.Business Model Tuduu operates primarily on a performance-based affiliation fee of 10% on sales, coupled with a SaaS subscription starting at €99/month for access to advanced platform features. Custom projects and media services (including influencer campaigns) are offered to support brand promotion and growth.The Tuduu Ecosystem and Team The platform is built on three key scalable AI models:Product Model: Analyzes and translates product data with nutritional profiling and cross-contamination detection.Recipe Model: Automates recipe nutrient calculation and compatibility with specific dietary needs.Nutrition Model: Generates personalized nutrition plans and profiles.The Tuduu team combines expertise in food tech, software development, UX design, marketing, and business development, driven by a shared mission to support Italian food producers’ digital transformation and international expansion.Sustainability and Impact Tuduu embraces sustainability not only as a goal but as a driver of growth. By promoting healthier eating habits through nutritionist-guided recipes and improving access to authentic local products, Tuduu aligns with several United Nations Sustainable Development Goals (SDGs). The platform also supports small producers by facilitating their entry into global markets via digital channels, thereby enhancing social and economic sustainability in local communities.Side Project: Tuduu Nutrition Expanding the core technology, Tuduu has developed a complementary SaaS platform for nutritionists called Tuduu Nutrition. This platform enables rapid creation, analysis, and digitization of personalized nutrition plans, integrated into a mobile app for patient compliance and monitoring.Key features of Tuduu Nutrition include:Generation of tailored nutrition profiles and plans based on validated dietary guidelines.Weekly meal planning with integrated recipes from Tuduu’s extensive database.Shared and collaborative shopping lists that automatically sync with partner retailers for easy purchasing.SaaS pricing based on a monthly subscription (€29/month) plus a fee per managed patient (€2.5/month).Tuduu Nutrition leverages the same AI technology and data models as Tuduu.it, creating synergy between food e-commerce and health-oriented nutrition planning.Financial Outlook and Fundraising Tuduu is currently in a growth and fundraising phase, targeting €1,000,000 in capital with investment tickets starting from €5,000. The company projects rapid scaling with increasing revenues from marketplace transactions, media services, and SaaS subscriptions, aiming for over €11 million in revenues by 2029 and expanding its brand network substantially.Summary Tuduu.it is poised to transform the Italian food export landscape by bridging the gap between small producers and international consumers through advanced AI-driven digital tools, an engaging marketplace experience, and a strong commitment to sustainability and nutrition. Alongside its sister platform Tuduu Nutrition, it creates a comprehensive ecosystem that connects producers, consumers, and health professionals in a unique, scalable way.
• Blade of God X — Blade of God X provides cross-platform play as an optimum medium and way of interaction between people and the virtual world.

Portfolio highlights

• treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.