Top 50 Medical Startup Investors in Italy (September 2026)

Portfolio highlights

• Mopso — Discover Mopso's anti money laundering detection system. Visit our website and try a 30 minutes free demo with one of our experts.
• Klaaryo — Klaaryo is the Conversational AI platform that helps organizations transform how they attract, hire, onboard, and develop their people.We design native AI Agents that communicate in natural language, understand people’s needs, and orchestrate complex HR processes in a simple, immediate, and scalable way.Our approach is WhatsApp-first, built toexpand into a multi-channel ecosystem that brings conversational intelligence everywhere people work, communicate, and interact.
• ExoLab Italia — Cosmetics Utilizing plant-derived exosomes in cosmetic products boosts skin absorption, enhancing bioavailability and stimulating cells to produce lacking compounds. Their ability to penetrate the dermis ensures maximum efficacy and optimal results for skincare products. more informations Supplements Plant-derived exosomes, rich in nutrients, enhance bioavailability by

Portfolio highlights

• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• AUDIOGEN — Generate your sounds with AI. Create an infinite world of sounds - sound effects, samples, and music, instantly. Get Started Free.
• Alomana — Autonomous systems for enterprise

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• Neuromod Devices — Neuromod is the global medical device company that developed Lenire, the FDA Approved tinnitus treatment device.
• DISCO Pharmaceuticals — DISCO Pharmaceuticals is a firm that specializes in large-scale surfaceome unlocking of cancer cells.
• Endovascular Engineering — Endovascular Engineering is a medical technology company focused on developing and deploying advanced clot removal solutions for the treatment of venous thromboembolism. It specializes in thrombectomy technologies designed to improve clinical outcomes and procedural efficiency in minimally invasive vascular interventions. The company’s flagshipinnovation is the Hēlo™ Thrombectomy System, a catheter-based device that uses a combination of mechanical agitation and physician-controlled aspiration to remove blood clots. Its technology emphasizes features such as a self-expanding funnel design and dual-action functionality to enhance clot engagement and navigation through complex anatomies. Endovascular Engineering primarily serves healthcare providers, including interventional cardiologists and radiologists, supporting the treatment of conditions such as pulmonary embolism and deep vein thrombosis.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• Rainbow Crops — Rainbow Crops is a next-generation Agtech company developing climate-resilient, high-performing crop varieties.
• Wearable Robotics — Wearable Robotics produces and develops wearable robotic systems and exoskeletons for rehabilitation, assistance and human-power augmentation.

Portfolio highlights

• Gility — Gility is a digital learning platform that collaborates with business schools and training institutions for an effective training offer. Established in 2022, it was supported by CDP Venture Capital and BPER Banca.
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.
• Valvitalia SpA. — VALVITALIA is a leading group in the field of design, production, and overall supply of equipment and components intended for the petroleum, water, natural gas industries, and petrochemical industry as well as electrical power stations. The group works mainly with valves (core product), actuators, pipe fittings, flanges and systems for measuring,filtering, and regulating fluids and gases and with FireFighting systems. VALVITALIA was set up with the precise objective of becoming the leading Italian group able to offer such a wide range of products and to compete with the large American multinationals that have always dominated this field. This young company has extensive experience in the sector, thanks to its professional management and historical brands in the valve world that have been taken on by the Group, including: ROTOR, DELTA V.E., THEVIGNOT, VANADOUR, VITAS, TORMENE T.G.T. and TECNOFORGE. VALVITALIA has always included safety and respect for the environment and its employees among its priorities.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — BigProfiles is an Artificial Intelligence Platform designed for Utilities, Telcos, Banks, Insurance companies and Retails.Large companies such as Teleperformance, Eni, Unicef already have already successfully subscribed to our services.BigProfiles is the No-Code Artificial Intelligence Platform for sales and antichurn that predicts thelikelihood to purchase and churn of each customer in a CRM, before proceeding to contact him in a sales or retention campaign.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• Relicta — Relicta solution is a water-soluble bioplastic material obtained from fish processing waste and suitable for packaging solutions.
• OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
• LOTO Biotech — LOTO Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations.

Portfolio highlights

• Newcleo — newcleo is the clean and safe nuclear technology company. Privately funded and headquartered in London, UK, newcleo was launched in 2021 to be a disruptor in the field of nuclear energy. Its mission is to generate safe, clean and inexhaustible energy for the world, through a radically innovative combination of existing, accessible technologies.newcleo is building the next generation system with the goals to: (1) eliminate the need for geological repositories by using a fast neutron flux avoiding production of long life radioactive elements; (2) develop an Accelerator Driven System (ADS), based on the intrinsically safe coupling of a particle accelerator and a sub-critical reactor; (3) accelerate the development of new fuel cycles, including thorium, that provide economic, clean, safe and inexhaustible energy from nuclei and the opportunity to burn the long-lived nuclear waste produced by the old generation of nuclear reactors.With visionary co-founders, newcleo brings together a team of engineers with deep knowledge of nuclear energy with younger recruits with a fresh mindset, working to design an innovative micro Lead Fast Reactor with significant commercial applications, for example in shipping. newcleo wants to be the first step toward the evolution of its industry to become fully respectful of people and the environment. To develop a new, sustainable, and completely safe way of generating nuclear energy that will lead humanity to zero emissions, and to the mitigation of global warming.
• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• Scuter — Scuter is the smart e-scooter sharing service that makes city mobility,simple, enjoyable and sustainable. Scuter is on well on its path toward making a dent in this space.
• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• Health Triage — Health Triage, crea nuove tecnologie per offrire modelli innovativi di diagnosi clinica, identificazione e cura delle malattie oncologiche.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Passpack — Users can make and store passwords in a single, organized list, then access them from anywhere leaving no traces behind on the computer. Secure collaboration features allow users to make, send, share or provision passwords to colleagues, clients and partners -- a secure alternative to spreadsheets in the workplace. Managed via a central onlinerepository.Passpack is a free, professional tool. Optional premium upgrades are available for the micro-small business sector.
• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.

Portfolio highlights

• HEU — Draft, sign and store contracts in one place. AI extracts deadlines and clauses, signatures valid in 180+ countries.
• Tech4All — We support the study by using AI.
• GeneSys Bio — Antimicrobial Resistance (AMR) is a global health emergency projected to cause 10 million deaths annually by 2050. The crisis is fueled by slow, conventional diagnostics that take 3-5 days, forcing the empirical use of broad-spectrum antibiotics and accelerating the spread of superbugs.GeneSys Bio is commercialising a breakthrough solution: afully automated, sample-to-result molecular diagnostic platform that identifies infectious pathogens and their critical antibiotic resistance genes in under 30 minutes with >99% sensitivity and specificity. Our portable, laptop-sized device combines proprietary nucleic acid amplification with an AI-driven engine to deliver clear, actionable results directly to clinicians, veterinarians, and public health officials.Our platform is a modular "One Health" solution, adaptable via disease-specific kits for human, veterinary, and environmental applications. We are entering the market with a diagnostic for Urinary Tract Infections (UTIs), a condition affecting over 500 million people annually and a primary driver of antibiotic misuse. By enabling targeted therapy at the first patient encounter, our platform is set to reduce treatment costs by up to 13%, cut follow-up visits, and decrease mortality from complicated infections by 50%.GeneSys Bio is positioned to capture a significant share of this market by bridging the critical gap between speed, laboratory-grade accuracy, and accessibility. We are not just creating a device; we are building the future of decentralized infectious disease diagnostics to safeguard global health for generations to come

Portfolio highlights

• Cosmico — We are the platform connecting digital talents with the most ambitious companies, using remote work.We have over 8,000 members and our talents have accelerated dozens of projects alongside big names like Accenture Song, Tangity, Frog, Fjord, Sketchin, EY but also aggressive start-ups like Scalapay, Gimme5, Flowe, Unguess.If you are a digitalprofessional: we offer you a community in which to grow your talent through experiences, networks and cosmic projects.If you are a company: we offer you access to a community of designers, developers and marketers from which to select the talents to accelerate your digital transformation projects. Whether you are a manager or a digital professional, Cosmico is here to help you find your space
• A-Cube — A-Cube API: la piattaforma globale per la Tax Compliance. Integra la fatturazione elettronica e gli obblighi fiscali in ogni ERP o e-commerce in Italia e nel mondo.
• Incapto Coffee — Incapto provides coffee solutions that combine specialty whole-bean coffee, super-automatic coffee machines, and subscription-based delivery services for consumers and businesses. The company supplies freshly roasted coffee beans sourced from multiple origins and delivers them directly to customers through recurring subscriptions, ensuringcontinuous availability and freshness. Its offering includes fully automatic coffee machines that grind and brew beans on demand, enabling users to prepare coffee without single-use capsules or manual preparation steps. The company also provides workplace coffee solutions, supplying machines, beans, and technical support for offices, hotels, and food service environments.Incapto integrates digital tools that track consumption, manage inventory, and automate replenishment, allowing customers to monitor usage and receive supplies based on demand. It also offers complementary products such as accessories, beverages, and maintenance services to support ongoing operation of its coffee systems.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• I-VASC — I-VASC has developed the VELEX device using new technology to treat CVI and varicose veins.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Recornea — Recornea is a developer of a corneal medical device to restore the physiological curvature of the cornea with clear and predictable clinical outcomes.
• Health Triage — Health Triage, crea nuove tecnologie per offrire modelli innovativi di diagnosi clinica, identificazione e cura delle malattie oncologiche.

Portfolio highlights

• Verado — Verado is a global technology platform designed to empower everyone to instantly monetize their belongings. Whether selling an old laptop or unlocking cash by collateralizing valuables for a loan, our technology is crafted to enable consumers to do so with unprecedented ease. Snap a picture of your electronics, valuables, apparel or otherbelongings, get an instant appraisal through our real time valuation engine, and receive a direct payout to your bank account immediately. We are a deep technology company, envisioning a world where products’ lifecycle is lengthened and the ecological burden of trashing minimised. What exists currently is falling short of the experience modern consumers expect. They value convenience, comfort and speed, and don’t deem existing selling channels even marginally satisfactory. They are tired of the tedious paper-work, negotiating with uncommitted buyers through outdated messaging systems, managing the logistics, and the time-consuming nature of the process. Through our innovative solutions, we are cutting down from days to seconds the time it takes to receive a valuation; and from weeks to hours, the time necessary to sell!Verado is changing the rules of the game - It’s simplicity, re-engineered. We believe selling should be as seamless as buying. Therefore, rather than accumulating unused products at home or worse letting them end up in a landfill forever - we enable individuals to monetize their unwanted things, free up valuable space in their home and reduce their need for borrowing whilst simultaneously minimizing their ecological footprint.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• Evja — Evja supports growers in optimizing the management and monitoring of irrigation, nutrition and protection of their crops through the use of OPI, the most advanced system for precision agriculture .
• BionIT Labs — We apply IT to Bionics in order to Turn disabilities into New Possibilities
• Planeat.eco — Planeat.eco is the site where you can plan your food shopping in a simple and economical way, starting from the recipes and receiving at home all the ingredients ready for preparation , weighed and divided into compostable containers. They offer their products online.

Portfolio highlights

• iwoca — Iwoca provides financing to businesses for various purposes, including bridging short-term cashflow gaps and investing in stock opportunities. It services retailers, restaurants, hotels, and other businesses. It offers flexible repayment options from 1 day to 24 months, with no penalties for early repayment. Iwoca helps businesses manage cash flowgaps and invest in growth opportunities, enhancing their financial capabilities.
• Straiker — Security for agentic AI applications built from the ground up with fine-tuned models to protect and secure every layer of your agentic AI stack.
• Nuclidium — NUCLIDIUM is a clinical-stage radiopharmaceutical company that develops novel radionuclide PET tracers for precision diagnostics. Using copper isotopes, Copper-61 for diagnostics and Copper-67 for therapeutics, the company is creating a differentiated platform with the potential to overcome existing limitations in radiotheranostics.

Portfolio highlights

• C.NEXT — C.NEXT develops innovation projects for businesses and organizations by supporting the economy and territorial regeneration.
• Vivavoce — Il centro medico Vivavoce, Specializzato nel trattamento riabilitativo della #balbuzie. Disturbi del Linguaggio, DSA, Psicologia e Neuropsichiatria infantile.
• Way Experience — Way Experience operates in all the entertainment B2C sectors, using augmented and virtual reality technology. They also work in the B2B area by applying their technologies for customized consultancy projects in the following sectors: design, fashion, medical, events, and training.

Portfolio highlights

• VENPA — Noleggio Piattaforme Aeree e Noleggio Macchine Movimento Terra. Scopri tutti i mezzi da cantiere Venpa!
• Tony Kart — Tony Kart is an automotive company specializing in designing and manufacturing chassis, OTK kart parts, and karting wears.
• Hippocrates — Hippocrates operates a pharmacy platform with a network of over 120 owned pharmacies concentrated in central and northern Italy. Since its foundation, it has approached the pharmacy sector with an industrial and long-term logic. The company was founded in March 2018 by Davide Tavaniello and Rodolfo Guarino, co-CEOs of Hippocrates.

Portfolio highlights

• Palyon Medical — Palyon Medical Corporation is a medical device company developing technologies for the treatment of chronic pain, spasticity and other neurological diseases.
• Neuromod Devices — Neuromod is the global medical device company that developed Lenire, the FDA Approved tinnitus treatment device.
• Vivasure Medical — Pioneering the Future of Large-Bore Vessel Closure for Arterial and Venous Access. The first and only 100% bio-absorbable, sutureless patch..

Portfolio highlights

• qomodo — Qomodo: La piattaforma BNPL innovativa. Rate a tasso zero, approvazioni veloci, transazioni sicure. Rivoluzionaria nell'acquisto per aziende e consumatori.
• Serenis Health — Serenis Health provides video-based psychotherapy, coaching, and psychological support courses. It believes that the internet is critical to increasing access to mental health care. It makes use of data and digital tools to improve the efficacy of therapies. But, unlike other platforms, it is also a medical center, which means it is responsible forcourse quality and must meet the same standards as any polyclinic.
• AutoConnexa — Scopri AutoConnexa, l'assicurazione online per la tua auto che premia lo stile di guida. Con Drive Connexa, meglio guidi e meno paghi.

Portfolio highlights

• Busforfun — Shared and Green traveling to experience the world of fun#WeTheFun | Busforfun is a young mobility company traveling in a sustainable, safe and low-cost way across Europe. Busforfun vision is a green and shared mobility to experience the world of fun.#WeTheTech | Busforfun is a combination of high tech-startup, e-commerce-platform andtransportation company, Busforfun is going to establish European largest bus network for events in the short time. Thanks to a powerful search engine, business intelligence, an user-friendly booking system and an extensive route network, Busforfun offers travellers the opportunity to experience the world of fun with lower fares.#WeTheGreen | Our low-emission buses comply with the highest safety and environmental standards, so Busforfun offers a sustainable and convenient alternative to cars. With main partner Treedom, Busforfun plants new trees at any travel worldwide.Live Fun Experience in partnership – our concept for successBusforfun provides customers with great offers at lowest budget, through smart network planning, dynamic price management and an adaptive web engine.Busforfun platform is where the innovation and start-up spirit meet the experience and know-how of traditional bus companies and travel agencies.Incredible success can be attributed to the digitalization of old-fashioned bus travel industry: Busforfun has not suppliers or clients: but partners only!
• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• Faccin Group — Faccin Group leads in manufacturing top tier metal forming & bending machines. Operating as Faccin, Roundo & Boldrini, we offer unparalleled expertise.

Portfolio highlights

• Fore Biotherapeutics — We are a precision oncology company pioneering the development of cancer therapies guided by our proprietary functional genomics.
• Epsilogen — IGEM Therapeutics is a developer of an immuno-oncology company intended to develop immunoglobulin antibodies to treat cancer.The company's offerings include IgE-based drugs targeting solid tumors, enabling patients to kill parasites which reside in human tissue, also the home of the solid tumor.
• Kainova Therapeutics — Domain Therapeutics is a biopharmaceutical company focused on GPCR in immuno-oncology. Discover more than you think on our innovative cancer treatments tackling GPCR mediated-immunosuppression

Portfolio highlights

• Baluwo — Providing basic essentials has never been this easy. Sending money is not always the solution so we provide easy, fast & convenient ways to send prepaid electricity top-ups, mobile top-ups and basic food items to support your family back home in The Gambia, and very soon in Senegal and Nigeria.
• Freedome — Freedome is the leading marketplace for outdoor activities in Italy
• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• CityFibre — CityFibre is a brand new full fibre network built for the data age. Never worry about speed or reliability again. Connect your home and business today.
• Power Dot — Powerdot offers electric vehicle charging solutions in convenient locations across six European countries.
• Origis Energy — Origis Energy is powering the solar revolution with solar power and energy storage projects for utility, corporate and public sector energy clients.

Portfolio highlights

• Gardin — We believe in a world in which everyone has the right to access high quality, nutritious food that is good for you and for our planet. Our environmental issues are real, something, somewhere needs to change. Gardin promises to create the step-change required by deploying its technology.
• NoTraffic — NoTraffic has developed the first AI-powered traffic signal platform that connects road...
• Stellar — At Stellar we bring perfect internet on the move to vehicles and passengers, leveraging the combined strength of cellular, wi-fi, and satellite networks, through AI and fully integrated solutions. We offer SaaS, data plans, and all-inclusive options for enterprise connectivity needs on the move.

Portfolio highlights

• CiaoDott — Automatizza le telefonate, prenotazioni e FAQ del tuo studio medico con CiaoDott, l'assistente vocale AI disponibile 24/7. Provalo gratis.
• Octostar — Octostar is the sovereign, AI-powered investigative intelligence platform for law enforcement, national security and financial institutions.
• Mirai Robotics — Autonomy and intelligence for the seas. We're building software-defined autonomous systems and AI platforms that unify vessels, sensing, and command at sea.

Portfolio highlights

• EBAMed — EBAMed SA is a Swiss startup based in Geneva whose mission is to enable safe and effective non-invasive treatments of heart arrhythmias with protontherapy. The company is currently developing a medical device to enable non-invasive heart motion imaging and real-time synchronization of the therapeutic beam. This device consists in both hardware andsoftware components and expands treatment possibilities for existing protontherapy centres, enabling them for the first time to treat heart patients.
• Hylomorph — Hylomorph is a clinical-stage medical device company developing innovative materials designed to transform the biocompatibility of implantable medical devices.
• CV Lab — CV Lab is the first incubator fully focused on cardiovascular innovation in Europe. It supports the most promising ideas through patenting, prototyping, and proof of concept until they mature enough to give life to a spin-off and meet international capitals. CVLab puts to good use the experience of entrepreneurs and specialists with strongexpertise in biomedical. The company collaborates with experts in the field. CVLab is a lean organization, close to researchers and clinical needs.

Portfolio highlights

• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• Banxware — Banxware provides the technology and the funds for business financing of any kind: fully embedded in your platform or as an affiliate solution - all managed by Banxware
• Greenvolt Power — Greenvolt Power is a renewable energy platform that develops and operates onshore Wind and photovoltaic installations. Greenvolt Power is a global producer of renewable electricity that relies on experienced employees in Europe and the United States to apply their know-how and expertise to solar and wind projects, as well as energy storage.
• Polo Strategico Nazionale — Scopri Polo Strategico Nazionale: il cloud sovrano per la gestione dei dati e servizi della Pubblica Amministrazione italiana.

Portfolio highlights

• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• Biorfarm — Adotta il tuo Albero, crea il tuo Campo Digitale e ricevi a domicilio la tua frutta biologica. Solo con Biorfarm puoi seguire la crescita dei tuoi frutti!
• EvenFi — Criptalia uses blockchain technology to connect businesses that have projects to be funded with people and organizations who are looking for high-yield investments. We offer an online platform where companies publish their innovative ideas and industrial improvement projects. Investors, people, and institutions can fund these projects by lendingmoney in exchange for a higher interest rate.
• Latitudo40 — Empower sustainable growth with AI-driven satellite insights from Latitudo 40. Unlock precise, real-time data for smarter urban planning, climate risk management, and industry innovation. Enhance resilience and lead with confidence.

Portfolio highlights

• TeiaCare — TeiaCare is an Italian start-up born in 2018 with the aim of transferring technology and innovation knowledge to care homes.Our first solution, Ancelia, is an AI-powered operating system designed to increase transparency in the care and assistance processes, both inside the care home and towards residents' families.TeiaCare, based inMilan, operates in Italy and Spain, has a team of 15 people and is supported by international investors.
• VoiceMed — We bring deep-tech innovation into your smartphone. With vocal biomarkers and artificial intelligence, we measure respiratory diseases.
• Hale — Hale is the digital solution supporting people with genito-pelvic pain, helping them live better with their condition. Download our app now!

Portfolio highlights

• BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...

Portfolio highlights

• Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Portfolio highlights

• Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
• Maticmind S.p.A — Maticmind S.p.A is a company that provides ICT and system integration solutions to telecommunications operators.
• Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Portfolio highlights

• Viceversa — Viceversa provides capital to European digital businesses to support companies in sustainable and ethical growth. The company was founded in 2021 and has locations in Milan and Dublin.
• Hercle — Hercle is a regulated digital asset liquidity provider specializing in OTC trading and market making.
• Underscore District — Underscore District unlocks the potential of Made in Italy fashion brands through the power of technology and data analytics.

Portfolio highlights

• Altoida — Altoida is creating a new gold standard in brain health with Precision Neurology. We're radically transforming the method for measuring brain function and diagnosing neurological disease, using just your smartphone or tablet.Our products are backed by more than 20 years of innovative research in digital biomarkers, augmented reality (AR),and artificial intelligence (AI).Altoida received FDA Breakthrough Device Designation in July 2021. Our first device is a Computerized Cognitive Assessment Aid that is classified as Class II, 510(k) exempt.
• SMART VALOR — SMART VALOR is a secure investment platform offering easy buy and sell of cryptocurrencies like Bitcoin, Ethereum, Dash and more. Trade and store digital assets.
• JenaValve Technology — Redefining what it means to treat patients with severe aortic regurgitation.

Portfolio highlights

• Perfuze — Perfuze was founded in 2018 by Wayne Allen and Liam Mullins. Perfuze is located within Galway City in the West of Ireland. The founders have over 30 years combined medtech experience within start-up and large corporations.Perfuze is developing innovative medical technology to treat acute ischemic stroke.Perfuze is developing innovative cathetertechnology to treat acute ischemic stroke. Their technology is intended to provide superior clinical outcomes in shorter procedural times; resulting in safe, cost-effective therapy. Perfuze was founded in 2018 by Wayne Allen and Liam Mullins. The founders have over 30 years combined medtech experience within start-up and large corporations. Perfuze is currently located in the Business Innovation Centre on the campus of the National University of Ireland, Galway, and is in the process of relocating to the IDA Business Park in Dangan, Galway.
• Novate Medical — NOvate Medical Technologies is a New Orleans-based medical device development company, focused on commercializing high-quality, low-cost, and sustainable medical products while addressing critical global health needs. NOvate’s first product offering, InfaClip, previously known as SafeSnip, is a patented disposable plastic obstetric device thatsimultaneously cuts, clamps, and shields the infant, mother, and birthing attendant from infection, aimed at reducing maternal and neonatal mortality in developing countries.
• INNOVO by Atlantic Therapeutics — INNOVO is a completely non-invasive, clinically proven and long-lasting solution to urinary incontinence and bladder weakness. See results in 4 weeks!

Portfolio highlights

• NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
• ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• Clean Cells — Clean Cells is your reliable CMO/CRO for cell and virus banks manufacturing with a strong expertise in Quality Control Testing for all kind of Bioproducts from R&D to market and in compliance with worldwide regulatory agencies.
• PlasmidFactory — PlasmidFactory is the leading contract manufacturer and service provider for plasmid DNA and minicircle DNA, custom DNA, In-Stock DNA for AAV and clinical application
• Corealis Pharma — Corealis Pharma provides services on a contract basis in the areas of formulation and process development as well as in small-scale clinical trial material manufacturing and the packaging of solid dosage forms to pharmaceutical and biotech companies. Its services include API characterization, salt selection, pre-formulation, formulation and processdevelopment, analytical method development, stability storage, and testing, technical transfer and scale-up, cGMP manufacturing and packaging of phase I and II CTM, and dossier support.

Portfolio highlights

• Ossio — OSSIO is an orthopedic fixation company committed to transforming the orthopedic experience for patients, physicians, and payors. Their vision is to provide the first credible replacement to metal implants in the $10B+ orthopedic fixation market (screws, pins, plates) with an Intelligent Bone Regeneration Technology. OSSIOfiber represents abreakthrough material platform for orthopedic and podiatric surgeons who seek a more biologically friendly way to restore patient stability and mobility with nothing permanent left behind.Founded in 2014, OSSIO began as the culmination of years of biomechanical research and a vision for the possibility of better bone healing. The technological basis of OSSIOfiber™ was developed and would lay the groundwork for ushering in a new breakthrough category of non-permanent fixation, “Bio-Integratives” hardware that has both desired strength AND bio-friendliness. Hardware that has the mechanical strength for easy insertion and secure fixation, while enabling the body to regrow bone, incorporating and replacing the implant (without the adverse inflammation and weakness often seen in “bio-resorbables and other “bio-composites”), has remained elusive to the industry until now.
• Icotec — Icotec develops and produces carbon fiber reinforced plastic implants for spine surgeries and accident treatments.
• Nalu Medical — Nalu Medical is an early-stage company that develops a range of medical devices. Their vision to modernize and improve the technology in medical devices, thus improving the lives of people.The Nalu neurostimulation system is a battery-free, micro-implantable pulse generator (iPG) currently cleared by the FDA for both Spinal Cord Stimulation (SCS)and Peripheral Nerve Stimulation (PNS) for mitigating chronic pain. The company was founded in 2014 and is based in Carlsbad, California.

Portfolio highlights

• Syndax Pharmaceuticals — Syndax Pharmaceuticals is a clinical-stage pharmaceutical company that focuses on an HDAC inhibitor for solid tumors and hematological tumors. It offers therapies to treat solid tumors and lung, breast, and hematological cancer. The company is developing axatilimab, a monoclonal antibody that blocks the colony-stimulating factor 1 (CSF-1) receptor,in development for chronic Graft versus Host Disease, and entinostat, a class I HDAC inhibitor.Syndax Pharmaceuticals pipeline includes and SNDX-5613, a highly selective inhibitor of the Menin–MLL binding interaction, in development for the treatment of patients with MLLr and NPM1 acute leukemias.
• Portola Pharmaceuticals — As Alexion, AstraZeneca Rare Disease, we are delivering life-changing therapies to people living with rare diseases.
• Rhythm Pharmaceuticals — Rhythm Pharmaceuticals is a global biopharmaceutical company committed to transforming the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.

Portfolio highlights

• BIT ODD — Gaming company building games filled with wonder, weirdness and delight
• Dream Games — Join Dream Games and explore a vibrant universe of characters and puzzles. Discover why millions of players worldwide love our mobile games. Visit us to learn more about our games, company culture, and career opportunities.
• Acutus Medical — Acutus Medical develops medical technologies to treat complex cardiac arrhythmia. The company's platform displays the heart’s true activation pattern, turning the chaos of a complex arrhythmia into a clear vision for electrophysiologists.Acutus Medical is a privately funded company founded in 2011 and based in Carlsbad, California. Itsproducts are co-developed in the U.S. and Europe with an exceptional team of medical scientists, biomedical engineers, and other professionals.It was founded in 2011 and headquartered in Carlsbad, California.

Portfolio highlights

• Convoy — Convoy uses technology to make freight more efficient, reduce shippers' costs, increase carriers' earnings, and eliminate carbon emissions.
• FinCompare - Smarter Business Finance — FinCompare was founded by Stephan Heller and is a fintech startup that helps businesses to find, compare, and close the financing solutions. Via the online platform, companies can access a wide range of financing options. They can independently compare offers from well-known banks, fintechs, and alternative financial services providers in Germanyand close the financing. The company also offers a convenient one-stop destination for all financing questions relating to the company.FinCompare financing solutions including corporate loan, factoring, company leasing/hire purchase, warehouse financing, fine trading/purchase financing, and mezzanine capital. It simplifies the financing process with its digital application process and can thus provide your company financing. The company allows SMEs to receive and compare various offers for loans.FinCompare was founded in October 2016 by Stephan Heller and is headquartered in Berlin, Germany.
• Finom — Finom combines digital business account benefits with multiple services to provide financial solutions for entrepreneurs, self-employed, and freelancers. It pulls together accounting, financial management, and banking functions for early-stage businesses and SMEs into one mobile-first product.Founded in 2019, Finom is headquartered in Amsterdam,The Netherlands.

Portfolio highlights

• DAXOR — DAXOR Corporation is an innovative medical instrumentation and biotechnology company. DAXOR designed and developed the BVA-100 Blood Volume Analyzer. It is the first instrument approved by the FDA to provide rapid direct measurement of a patient's true blood volume. We believe that the BVA-100 Blood Volume Analyzer has the potential totransform therapy in a broad range of surgical and medical conditions. It is our goal, working in conjunction with hospitals and clinics, to achieve that possibility.The BVA-100 is a semi-automated Blood Volume Analyzer. It is used in conjunction with a single use diagnostic kit. It is the first FDA-approved instrument to provide rapid direct measurement of a patient's blood volume.
• Preteckt — Preteckt's AI software predicts & prevents breakdowns in buses & coaches. Reduce costs, maximize uptime, & extend vehicle life
• Daily Crunch — Daily Crunch is an offline and online store that offers cherry-berry nuts, cacao sea salt, and sprouted almonds products.

Portfolio highlights

• Orfium — Find, use, track, and monetize music content across all channels with Orfium's industry-leading music rights management software.
• CyberRidge — CyberRidge is a deep-tech cybersecurity firm that develops photonic encryption to protect data privacy.
• Powerful Medical — Powerful Medical is a deep-tech company, tackling the most challenging problems of modern medicine using artificial intelligence and machine learning.