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Top 25 Cryptocurrency Startup Investors in Panama in September 2025

Last updated: Sep 2025 A list of 25 angel investors and VC (Venture Capital) funds that invest in Cryptocurrency startups based in Panama. We rank investors based on the number of investments they made in Cryptocurrency companies from Panama. We update this investor list every month.

Top 25 Cryptocurrency Startup Investors in Panama in September 2025

Investor	Cryptocurrency Panama investments
D1 Ventures	3
Morningstar Ventures	3
Loren Roosendaal	2
Animoca Brands	2
SevenX Ventures	2
ROK Capital	2
M. H. Carnegie & Co.	2
Huobi Ventures	2
Ghaf Capital	2
IVC	2
Arca	1
Akatsuki Games Inc.	1
MoonBoots Capital	1
InnMind	1
Danish Chaudhry	1
Mechanism Capital	1
Sarson Funds	1
Ghaf Capital Partners	1
Genblock Capital	1
MH Ventures	1
Eden Holdings	1
Richard Ma	1
Ascensive Assets	1
Kieran Warwick	1
Yield Guild Games	1

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Investor list

Powering the Future of Open Economy

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
Vistara Labs — Hardware Availability Layer
Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

We are a proprietary investment firm focused on digital assets and blockchain technology, primarily focused on the Elrond Ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Germany

Portfolio highlights

FereAI — Unlock real-time AI crypto insights and automated trading with FereAI. Discover top crypto trends, optimize investments, and start trading smarter with your personal AI team.
SYNTHR — SYNTHR utilizes omnichain synthetic assets to power a zero-slippage execution environment. The protocol brings together a combination of pull and push oracles, a zero-slippage omnichain liquidity layer, and multiple independent consensus layers, providing you with a unique cross-chain solution.
Arknet — Join Arknet, the distributed internet platform for secure, private communication, and advanced blockchain technology. Discover AI, neural networks, and Bitcoin integration.

Loren Roosendaal is the Founder and Chairman of Knowingo.

Investment focus

eSports, Blockchain, Online Games
Seed, Funding Round
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Animoca Brands is a metaverse and gaming venture capital firm that focuses on driving digital property rights to gamers and internet users through NFTs. It utilizes gamification and blockchain to develop and market a portfolio of mobile applications, games, and additional products oriented to educational learning to ensure transparency, security,and new business models.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

HackQuest — HackQuest is a Multichain Web3 developer and founder platform, with education, community events, hackathons, and accelerators at its core. HackQuest helps over 20 leading ecosystems such as Mantle, Solana, Arbitrum, and Linea onboard quality developers and supports developers to jumpstart their careers in Web3.
Quack AI — Quack AI is an artificial intelligence governance Layer for Web3.
VERB Technology Company — VERB Technology Company is a software-as-a-Service, or SaaS, applications platform developer. Its platform is comprised of sales enablement business software products marketed on a subscription basis. The applications are available in both mobile and desktop versions. It includes verbCRM, Customer Relationship Management application, verbLEARN,Learning Management System application, and verbLIVE, its Live Broadcast Video Webinar application.

SevenX Ventures is a Research-driven Crypto Venture Capital founded in 2020.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
PumpBTC — PumpBTC is a liquid staking protocol that aims to help Bitcoin holders to stake their bitcoins and earn yield while bolstering the security.
StakeStone — StakeStone is the best yield-bearing ETH with a decentralized yield optimizing service ready for mass adoption on layer2s.

ROK Capital is a multi-strategy hedge fund and accelerator aiming to grow the Korean crypto ecosystem.

Investment focus

Blockchain, Financial Services, Gaming
Seed, Series A, Funding Round
United States, Japan, Brazil

Portfolio highlights

Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
GAM3S.GG — The future of gaming offering game discovery, reviews, guides, news & quests for a full experience across Steam, PlayStation, Epic Games, Xbox, Nintendo and web3.
Snackclub — Learn more about play to earn games

M.H. Carnegie & Co. was launched by Mark Carnegie in 2010 with total equity commitments of $132 million to capitalise on the post financial crisis environment in the Australian market for smaller alternative investment opportunities. M.H. Carnegie & Co. was launched with a focus and expertise in expansion capital, as well as operating realestate.

Investment focus

Medical Device, Health Care, Medical
Series B, Seed, Series A
United States, Panama

Portfolio highlights

EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Huobi Ventures is a venture capital firm which focuses on projects related to blockchain technology, crypto assets, and digital currency.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

0XVM — 0xVM is a Infrastructure of rollup L2s in Bitcoin. And it's an EVM-compatible execution layer on Bitcoin. It brings Bitcoin to the next level by enabling Turing-complete smart contracts. 0xVM operates directly within Bitcoin's consensus layer, integrating an execution layer and a data consistency layer. By offering a platform forprogrammability on Bitcoin, 0xVM resonates with the BTC community's vision and principles and offers a scaling approach that enhances Bitcoin's utility while retaining its integrity.
SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.

Investment, M&A, Equity Capital, Debt Capital, Growth Capital, and VC Advisory Services.

Investment focus

Blockchain, eSports, Online Games
Seed, Funding Round
Kenya, Panama, United Arab Emirates

Portfolio highlights

myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Who we are We are investors and entrepreneurs helping define the next generation of Blockchain startups. Our Focus Passionate founders. Disruptive models. Borderless markets. Exponential effects. Our Geography Starting from...

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

Delabs Games — At Delabs Games, we want to create fun games that last a thousand years.
Orange Cap Games — Orange Cap Games is a game and experience design studio that creates digital and physical trading card games featuring Pudgy Penguins.
SuperGaming — At SuperGaming, we are putting India on the global gaming map.

Invest confidently in crypto assets with Arca-- an asset management firm offering institutional-caliber products for sophisticated investors.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, United Kingdom, Brazil

Portfolio highlights

Beamable — One line of code is all you need to build your own custom server logic via microservices along with a world of LiveOps tools and live services.
Beam — Beam enables you to send and receive payments with speed, efficiency, and security like never before.
Nevermined — Nevermined helps you monetize AI agents with flexible billing, licensing, payments, and real-time settlement. Get started for free.

Akatsuki offers MobileSocialGame services. They utilize cutting edge technology and ideas to realize and deliver their ambitions to their users. They provide new value to society through the services we manage daily. Providing services throughout the world that brighten up everyone's daily lives.

Investment focus

Media and Entertainment, Gaming, Content
Seed, Funding Round, Corporate Round
Japan, India, United States

Portfolio highlights

Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
Stems Labs — community and platform for collaborative creativity
MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

MoonBoots Capital, we add value, capital, and community to the most innovative decentralized blockchain technologies and projects.

Investment focus

Cryptocurrency, Blockchain, Online Games
Seed, Funding Round
United Kingdom, Panama, Singapore

Portfolio highlights

Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Deal-origination and data intelligence platform for startup founders and VC investors in web 3.0, crypto, blockchain verticals

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed
Panama

Portfolio highlights

Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Danish Chaudhry is a GP & Co-Founder at Paper Ventures.

Investment focus

Blockchain, Cryptocurrency, Decentralized Finance (DeFi)
Seed, Pre-Seed, Funding Round
United States, India, Canada

Portfolio highlights

Nexio — Nexio is a bitcoin scaling solution platform that helps to improve cryptocurrency's scalability by using parallelizing Bitcoin rollouts.
Turtle Club — Turtle is a distribution protocol, democratizing liquidity access, monetizing Web3 activities, and redistributing value fairly in DeFi.
Neutral Trade — Neutral Trade, an on-chain multi-strategy hedge fund platform, offers innovative delta-neutral trading and liquidity provisioning strategies to deliver consistent, risk-adjusted returns.

Mechanism Capital is an investment firm that invests in the cryptocurrency industry with a focus on decentralized finance or DeFi.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

DeFi.app — DeFi.app helps to make DeFi trading easier while keeping full ownership of crypto assets. It also helps to manage CEFI and DEFI more effectively.
MagicBlock — MagicBlock Labs is a gaming and technology firm that creates infrastructure for fully on-chain games.
Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Sarson Funds is an independent provider of blockchain technology cryptocurrency marketing and educational services. It focuses on the financial professional community and its clients.

Investment focus

Web3, Blockchain, Cryptocurrency
Pre-Seed
Panama

Portfolio highlights

Splyce Finance — dETF protocol. Permissionless, on-chain index- and yield ETFs.

GHAF Capital Partners is one of the first locally managed blockchain private investment firm based in Dubai, U.A.E.

Investment focus

Blockchain, Cryptocurrency, Finance
Seed, Funding Round, Pre-Seed
United States, India, Canada

Portfolio highlights

Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
Pixelverse — Pixelverse is a blockchain-based, pixelated P2E game.
Mavryk Dynamics — Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).

Genblock Capital invests exclusively in blockchain and cryptocurrency, with a focus on decentralized finance.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Pre-Seed
United States, Singapore, Switzerland

Portfolio highlights

OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
AINN Layer2 — A Bitcoin Layer2 Solution Built On AI-Driven Modular Architecture
Sanctum — Stake SOL and earn optimized LST returns from JupSOL, bbSOL, and more, and launch your own custom LST and Solana validator.

MH Ventures is a world class community-backed Venture Capital investing in top blockchain projects of the future

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Funding Round, Pre-Seed
United States, Singapore, United Arab Emirates

Portfolio highlights

HeyElsa — Harness the power of AI in Crypto with Elsa, your crypto co-pilot. Uncover opportunities, trade smarter, and maximize returns, all with unparalleled ease and safety.
PublicAI — PublicAI is a Web3 distributed AI training network that helps people to earn rewards by contributing data work.
Cold River Games — Cold River Games is a Swedish game studio currently developing the ARPG Crystalfall.

Eden Holdings operates as a venture capital firm.

Investment focus

eSports, Blockchain, Online Games
Seed
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Richard Ma is the Founder and CEO of Quantstamp.

Investment focus

Blockchain, Financial Services, Information Technology
Seed, Series A, Funding Round
Singapore, United States, Japan

Portfolio highlights

DuckChain — DuckChain engages in bridging telegram users into the blockchain space.
Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
YOAKE Entertainment — YOAKE Entertainment is a music studio that specializes in the planning, production, and development of entertainment content.

Ascensive Assets is a seed-stage venture firm that invests in blockchain-enabled companies across the full spectrum of web3.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Brazil

Portfolio highlights

StripChain — Stripchain is an intent-based interoperability standard that enables chain abstraction.
Nest Wallet — A Wallet Built for Traders
Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

Kieran Warwick Co-Founder at Illuvium

Investment focus

Cryptocurrency, Blockchain, Financial Services
Seed, Pre-Seed
United States, Canada, Panama

Portfolio highlights

Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.
Layer Social Labs — A home for global companionship and endless entertainment. Post More, Play More, Earn More.

Yield Guild Games (YGG) is a decentralized autonomous organization (DAO) for investing in non fungible tokens (NFTs) used in virtual worlds and blockchain-based games. The organization’s mission is to create the biggest virtual world economy, optimizing its community-owned assets for maximum utility, and sharing its profits with its token holders.

Investment focus

Gaming, Blockchain, Video Games
Seed, Funding Round, Initial Coin Offering
United States, Singapore, Australia

Portfolio highlights

LOScoin — LOScoin is a web3 gaming and social application based on telegram bot. LOScoin is committed to profoundly combining Web3's novel interactive experience with the passion of LOScoin's MEME community, creating a highly engaging, entertaining, and economically active DAO community, and providing users with a completely new gaming and socialexperience.
Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
Pixion Games — Pixion Games is a studio focused on building competitive esports games for mobile device.

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