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Top 25 Cryptocurrency Startup Investors in Panama in May 2025

Last updated: May 2025 A list of 25 angel investors and VC (Venture Capital) funds that invest in Cryptocurrency startups based in Panama. We rank investors based on the number of investments they made in Cryptocurrency companies from Panama. We update this investor list every month.

Top 25 Cryptocurrency Startup Investors in Panama in May 2025

Investor	Cryptocurrency Panama investments
D1 Ventures	3
Morningstar Ventures	3
SevenX Ventures	2
Loren Roosendaal	2
M. H. Carnegie & Co.	2
Ghaf Capital	2
Huobi Ventures	2
ROK Capital	2
IVC	2
Animoca Brands	2
Richard Ma	1
Einsvill Labs	1
InnMind	1
Danish Chaudhry	1
Yield Guild Games	1
Mechanism Capital	1
Ghaf Capital Partners	1
Genblock Capital	1
Akatsuki Games Inc.	1
MoonBoots Capital	1
MH Ventures	1
Eden Holdings	1
Ascensive Assets	1
SkyVision Capital	1
Arca	1

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Investor list

Powering the Future of Open Economy

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

The Arena — Arena. social is a cutting-edge SocialFi platform that is revolutionizing how content producers interact, network, and make money from their work.
Vistara Labs — Hardware Availability Layer
Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

We are a proprietary investment firm focused on digital assets and blockchain technology, primarily focused on the Elrond Ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Germany

Portfolio highlights

FereAI — Unlock real-time AI crypto insights and automated trading with FereAI. Discover top crypto trends, optimize investments, and start trading smarter with your personal AI team.
SYNTHR — SYNTHR utilizes omnichain synthetic assets to power a zero-slippage execution environment. The protocol brings together a combination of pull and push oracles, a zero-slippage omnichain liquidity layer, and multiple independent consensus layers, providing you with a unique cross-chain solution.
Arknet — Join Arknet, the distributed internet platform for secure, private communication, and advanced blockchain technology. Discover AI, neural networks, and Bitcoin integration.

SevenX Ventures is a Research-driven Crypto Venture Capital founded in 2020.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
PumpBTC — PumpBTC is a liquid staking protocol that aims to help Bitcoin holders to stake their bitcoins and earn yield while bolstering the security.
StakeStone — StakeStone is the best yield-bearing ETH with a decentralized yield optimizing service ready for mass adoption on layer2s.

Loren Roosendaal is the Founder and Chairman of Knowingo.

Investment focus

eSports, Blockchain, Online Games
Seed, Funding Round
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

M.H. Carnegie & Co. was launched by Mark Carnegie in 2010 with total equity commitments of $132 million to capitalise on the post financial crisis environment in the Australian market for smaller alternative investment opportunities. M.H. Carnegie & Co. was launched with a focus and expertise in expansion capital, as well as operating realestate.

Investment focus

Medical Device, Health Care, Medical
Series B, Seed, Series A
United States, Panama

Portfolio highlights

EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Investment, M&A, Equity Capital, Debt Capital, Growth Capital, and VC Advisory Services.

Investment focus

Blockchain, eSports, Online Games
Seed, Funding Round
Kenya, Panama, United Arab Emirates

Portfolio highlights

myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Huobi Ventures is a venture capital firm which focuses on projects related to blockchain technology, crypto assets, and digital currency.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

0XVM — 0xVM is a Infrastructure of rollup L2s in Bitcoin. And it's an EVM-compatible execution layer on Bitcoin. It brings Bitcoin to the next level by enabling Turing-complete smart contracts. 0xVM operates directly within Bitcoin's consensus layer, integrating an execution layer and a data consistency layer. By offering a platform forprogrammability on Bitcoin, 0xVM resonates with the BTC community's vision and principles and offers a scaling approach that enhances Bitcoin's utility while retaining its integrity.
SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.

ROK Capital is a multi-strategy hedge fund and accelerator aiming to grow the Korean crypto ecosystem.

Investment focus

Blockchain, Financial Services, Gaming
Seed, Series A, Funding Round
United States, Japan, Brazil

Portfolio highlights

Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
Snackclub — Learn more about play to earn games

Who we are We are investors and entrepreneurs helping define the next generation of Blockchain startups. Our Focus Passionate founders. Disruptive models. Borderless markets. Exponential effects. Our Geography Starting from...

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

GAIB — GAIB is the economic foundation for the future of artificial intelligence and computers. GAIB is a crypto-AI platform under development that tokenize GPUs, making AI computing—the processing power required to train and run AI models—more accessible.
Tarta Labs — Tarta Labs is dedicated to building a next-generation anime IP ecosystem and aims to innovate within the anime gaming space by blending engaging narratives, high-quality visuals, and community-driven gameplay experiences.
Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Animoca Brands is a metaverse and gaming venture capital firm that focuses on driving digital property rights to gamers and internet users through NFTs. It utilizes gamification and blockchain to develop and market a portfolio of mobile applications, games, and additional products oriented to educational learning to ensure transparency, security,and new business models.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

Memes Lab — Memes Lab is a multi-level meme infrastructure on TON, integrated with Telegram Stars, which allows users to purchase meme coins without a wallet.
Domin Network — Domin Network is a decentralized business network that connects software and hardware in many business situations using the NFT middleware protocol and DePIN rollup technology.
Slingshot DAO — Bet on the next billion dollar games! Slingshot is the AI Roblox Game Launcher, powered by the $SLING Token and home to Game Factory.

Richard Ma is the Founder and CEO of Quantstamp.

Investment focus

Blockchain, Financial Services, Cryptocurrency
Seed, Series A, Funding Round
Singapore, United States, India

Portfolio highlights

DuckChain — DuckChain engages in bridging telegram users into the blockchain space.
Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
Peach Worlds — Peach Worlds is the Squarespace for 3D immersive websites. It's the first no-code builder powered by AI, enabling designers to effortlessly create 3D websites without any coding.

An invesment fully drive into blockchain technology in Defi, SosialFi, GameFi, MachineFi, Web3 and all related in crypto

Investment focus

Blockchain, Cryptocurrency, Developer Platform
Seed, Funding Round, Secondary Market
Panama, United States

Portfolio highlights

NEAR — NEAR is the chain abstraction stack, empowering builders to create apps that scale to billions of users and across all blockchains.
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
Shiden Network — Shiden Network is a multi-chain decentralized application layer on Kusama Network. Kusama Relaychain does not support smart contract functionality by design - Kusama Network needs a smart contract layer. This is where Shiden Network comes in. Shiden supports Ethereum Virtual Machine, WebAssembly, and Layer2 solutions from day one. The platform supports various applications like DeFi, NFTs and more.

Deal-origination and data intelligence platform for startup founders and VC investors in web 3.0, crypto, blockchain verticals

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed
Panama

Portfolio highlights

Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Danish Chaudhry is a GP & Co-Founder at Paper Ventures.

Investment focus

Blockchain, Cryptocurrency, Decentralized Finance (DeFi)
Seed, Pre-Seed, Funding Round
United States, India, Canada

Portfolio highlights

Term Labs — Fixed rate lending for everyone
Nexio — Nexio is a bitcoin scaling solution platform that helps to improve cryptocurrency's scalability by using parallelizing Bitcoin rollouts.
Turtle Club — Turtle Club is a distribution Protocol, democratizing liquidity access, monetizing Web3 activities, and redistributing value fairly in DeFi.

Yield Guild Games (YGG) is a decentralized autonomous organization (DAO) for investing in non fungible tokens (NFTs) used in virtual worlds and blockchain-based games. The organization’s mission is to create the biggest virtual world economy, optimizing its community-owned assets for maximum utility, and sharing its profits with its token holders.

Investment focus

Gaming, Blockchain, Video Games
Seed, Funding Round, Initial Coin Offering
United States, Singapore, Australia

Portfolio highlights

LOScoin — LOScoin is a web3 gaming and social application based on telegram bot. LOScoin is committed to profoundly combining Web3's novel interactive experience with the passion of LOScoin's MEME community, creating a highly engaging, entertaining, and economically active DAO community, and providing users with a completely new gaming and socialexperience.
Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
Pixion Games — Pixion Games is a studio focused on building competitive esports games for mobile device.

Mechanism Capital is an investment firm that invests in the cryptocurrency industry with a focus on decentralized finance or DeFi.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

DeFi.app — DeFi.app helps to make DeFi trading easier while keeping full ownership of crypto assets. It also helps to manage CEFI and DEFI more effectively.
MagicBlock — MagicBlock Labs is a gaming and technology firm that creates infrastructure for fully on-chain games.
Mirai Labs — Mirai Labs is a game development company that offers web3, mobile apps, and blockchain services.

GHAF Capital Partners is one of the first locally managed blockchain private investment firm based in Dubai, U.A.E.

Investment focus

Blockchain, Cryptocurrency, Finance
Seed, Funding Round, Pre-Seed
United States, India, Canada

Portfolio highlights

Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
Pixelverse — Pixelverse is a blockchain-based, pixelated P2E game.
Mavryk Dynamics — Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).

Genblock Capital invests exclusively in blockchain and cryptocurrency, with a focus on decentralized finance.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Pre-Seed
United States, Singapore, Switzerland

Portfolio highlights

OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
AINN Layer2 — A Bitcoin Layer2 Solution Built On AI-Driven Modular Architecture
Sanctum — Sanctum offers the ability to launch millions of new LSTs utilizing solana.

Akatsuki offers MobileSocialGame services. They utilize cutting edge technology and ideas to realize and deliver their ambitions to their users. They provide new value to society through the services we manage daily. Providing services throughout the world that brighten up everyone's daily lives.

Investment focus

Media and Entertainment, Gaming, Content
Seed, Funding Round, Corporate Round
Japan, India, United States

Portfolio highlights

Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
Stems Labs — community and platform for collaborative creativity
MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

MoonBoots Capital, we add value, capital, and community to the most innovative decentralized blockchain technologies and projects.

Investment focus

Cryptocurrency, Blockchain, Online Games
Seed, Funding Round
United Kingdom, Panama, Singapore

Portfolio highlights

Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

MH Ventures is a world class community-backed Venture Capital investing in top blockchain projects of the future

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

Pizzapad — Pizzapad leverages cutting-edge AI technology to intelligently screen the most promising projects. Through data-driven predictions and automated due diligence, we bring you investment opportunities with high success rates.
Gata — Gata uses data technology to develop superintelligence and to ensure its alignment with human objectives.
Miden — Miden grants applications the power to scale with public and private transactions.

Eden Holdings operates as a venture capital firm.

Investment focus

eSports, Blockchain, Online Games
Seed
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Ascensive Assets is a seed-stage venture firm that invests in blockchain-enabled companies across the full spectrum of web3.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Brazil

Portfolio highlights

StripChain — Stripchain is an intent-based interoperability standard that enables chain abstraction.
Nest Wallet — A Wallet Built for Traders
Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

SkyVision Capital (SVC) promotes new, open decentralized technology and its development. We are a Crypto Fund that is dedicated to incubating and investing in founders of tomorrow, today.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

Demether — Demether is a DeFi protocol that works to enable zero-cost access to TVL for blockchains.
Amnis Finance — Stake APT on the best liquid staking protocol on Aptos to receive daily rewards with an attractive APR of 9%.
NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Invest confidently in crypto assets with Arca-- an asset management firm offering institutional-caliber products for sophisticated investors.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, United Kingdom, Brazil

Portfolio highlights

Beamable — One line of code is all you need to build your own custom server logic via microservices along with a world of LiveOps tools and live services.
Moku — Moku is a web3 gaming platform that enables players connect to gaming guilds, NFT casting pages, game strategy communities, and more.
Nevermined — Creating the Payment Infrastructure for AI-commerce. We help AI builders accept payments and manage usage of their apps, agents and GPTs.

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