Top 50 SaaS VC Funds & Investors in Panama (July 2026)

Portfolio highlights

• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Joystream — Joystream is a block chain-based, decentralized video platform.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• Itheum — As we enter the web3 and metaverse era; Itheum unlocks data silos and generates new value for your data.
• OP_NET —
• Watch.fun —

Portfolio highlights

• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
• BluWhale — BluWhale's mission is to leverage AI and ML to allow game developers to focus on ways to improve the game rather than wrangling and making sense of astronomical amounts of data. BluWhale's smart automation will do the heavy lifting usually reserved for data analysts and data scientists all in the background, and surface actionable insight
• Sorted Wallet — Sorted Wallet simplifies crypto transactions for feature phones in emerging markets.

Portfolio highlights

• Wizzwoods — Wizzwoods is an open-world farming strategy game.
• Metatheory — Metatheory Inc. is an interactive technology and entertainment company building Web3 games, interactive content, social experiences, and other community-driven adventures. Metatheory’s mission is to inspire imagination by connecting people worldwide through immersive worlds built on cross-generational IP.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
• Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.
• A.A.A C(H+A)RM — AAA C(H+A)RM (Autonomous AI Agents Launchpad & Layer3) is the first AI-first, agent-focused orchestration platform.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Sumer Money — Sumer Money is a cross-chain synthetic assets protocol that enables composable Defi across blockchains.
• SYNTRA — Syntra is an AI-driven trading infrastructure company focused on disciplined execution, real-time risk management, and transparent market operations in digital asset markets. The company builds systems that monitor market structure, volatility, liquidity, and correlation dynamics, enabling automated decision-making with strict risk controls.Syntra’s infrastructure is designed to prioritize execution quality, capital preservation, and operational transparency over short-term performance optimization.Syntra operates a live execution environment where all system actions are observable in real time, providing an open view into how the trading system behaves across different market conditions. The platform is infrastructure-first, emphasizing robustness, scalability, and controlled growth rather than aggressive user acquisition. The company is currently focused on expanding its execution stack, data pipelines, and risk management framework to support broader market coverage and institutional-grade reliability.

Portfolio highlights

• AEON — AEON is a crypto payment framework designed for AI-driven and real-world transactions. It supports omni-chain payments across ecosystems like EVM, SVM, and TON, enabling seamless cross-chain usage. Its solutions include AI-powered payments, Web3 online and mobile payments, QR/contactless acceptance, and swap pay, all designed to simplifyadoption for users and merchants.
• AlchemyNFT — AlchemyNFT is a non-fungible token (NFT) service.
• Limited — Secure your treasury and scale your business globally with a truly self-custodial account that only you control. No banks. No middlemen.

Portfolio highlights

• GameFi.org —
• AllScale — AllScale is a next-generation platform empowering small businesses to scale globally faster with stablecoin. Payroll: Automate cross-border payroll in stablecoins—simplify contractor payments, eliminate costly intermediaries, and ensure instant global delivery.Invoicing: Create, e-sign, and send professional contracts and invoices in seconds.Get paid by clients in their preferred method and instantly receive stablecoin—maximizing liquidity, minimizing friction.Social Commerce: Transform your followers into customers. Embed a dynamic AllScale biolink on your social profiles, showcase your offerings, and securely collect instant stablecoin payments directly from your audience.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• ANT.FUN — ANT.FUN is an innovative and emerging on-chain trading platform dedicated to providing secure, transparent, and efficient solutions for on-chain transactions.
• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• MSafe — MSafe offers the most secure, decentralized, scalable Web3 non-custodial, multi-signature solution built on Move, ideal for dApp developers to use for treasury management, token management, smart contract development, blockchain protocol admin control, live on Aptos
• Polysights — Polysights is an AI-powered prediction market analytics and automation platform that delivers market intelligence and trade execution tools.
• Turtle Club — Turtle aligns incentives between protocols and LPs to offer the best curated incentives in DeFi.

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Caden — Caden is the world's first Zero-Party Data platform. We allow users to own and control their own personal data, make money off it, and share it with trusted consumer brands, while maintaining their privacy.
• AnthologyAI — AnthologyAI is the breakthrough Artificial Intelligence Consumer Insights & Predictions Platform with billions of real-time data sourced directly and ethically from consumers. Access previously unavailable levels of intelligence about retail spending, geolocation, media consumption, travel, ride sharing and more — in realtime, at scale.
• Vero Technologies — Vero Technologies is a Financial Services based company.

Portfolio highlights

• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Portfolio highlights

• Splyce Finance — dETF protocol. Permissionless, on-chain index- and yield ETFs.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Euclid Protocol — Euclid creates a chain agnostic liquidity layer that allows any application to integrate and swap against an efficient market to provide the best user experience for users.

Portfolio highlights

• PACT — PACT designs Elegant materials produced in tune with the planet earth. It create revolutionary, sustainable biomaterials using the earth's resources, including collagen, herbal extracts, oils, and minerals.
• Rove — Claim your spot on the waitlist for the first ever travel credit card for Gen Z.
• Magrathea — Magrathea Metals is a mining company that unlocks centuries of growth in human civilization by reducing the socioenvironmental impacts.

Portfolio highlights

• Composable Corp — Composable Corp is a blockchain financial application developer.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• OpenPad AI — OpenPad - The 1st AI Decentralized Launchpad
• Stabble — stabble is a protocol revolutionizing liquidity pools by introducing protocol-managed and arbitrage pools. This allows stabble to tackle critical inefficiencies prevalent within Solana's decentralized exchanges.
• AI Cross Matrix — AI Cross Matrix is a DeFi platform that makes the crypto economy simple by streamlining the exchange process with useful solutions.

Portfolio highlights

• Demole — Demole is a play to earn NFT gamification platform.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Radom — A Decentralised Network for Coordination of Cloud Applications and Connected Assets

Portfolio highlights

• Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• VAST.app —
• Mavryk Dynamics — Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).
• Swarm Network — Swarm Network is a decentralized network for owning, controlling, and monetizing AI agents.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Amyl Therapeutics — Amyl Therapeutics is a preclinical stage biotechnology company. Amyl Therapeutics uses a novel mechanism to bind to the amyloid fold of toxic protein aggregates of various types, including antibody light chain (AL) or transthyretin (TTR) aggregates, which accumulate in peripheral organs to cause systemic amyloidosis diseases, but also amyloid-β(Aβ), Tau, and α-synuclein aggregates, which accumulate in the brain to cause Alzheimer's and Parkinson's diseases.

Portfolio highlights

• Anoma — A sovereign, proof-of-stake blockchain protocol that enables private, asset-agnostic cash and private bartering among any number of parties.
• Keplr — Introducing the first, and leading, IBC-enabled wallet for Cosmos and beyond
• Datachain — Datachain is a tech company that revolutionizes blockchain interoperability and stablecoin settlement. we aim to make it possible for the world to interact as one network, making it easier to use a variety of services.

Portfolio highlights

• Starbots — Starbots is Solana's first-ever battle NFT game.
• Linear — Linear allows the user to manage software development and track bugs. Built for speed and efficiency.The founders started Linear from their own frustrations building software projects in successful high-growth companies like Airbnb, Coinbase and Uber. The founders wanted to create the tools that focus us and its team in making progress, not getin the way. Tools that are fast and efficient. Speed and performance were the main things Linear focuses on early on and keep focusing on that.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• Ankr — Get faster, more reliable multi-chain development tools
• WOO Network — Discover WOO's ecosystem of centralized and decentralized apps to seize every opportunity in crypto.
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.

Portfolio highlights

• StripChain — Stripchain is an intent-based interoperability standard that enables chain abstraction.
• Nest Wallet — A Wallet Built for Traders
• Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• Infinity Arena — The place to connect players who love tactical card games or have passionate about collecting valuable and rare NFT cards.
• Ancient Kingdom — Ancient Kingdom is the first ancient martial arts game on the blockchain platform, pioneering the realization of real-time games on the blockchain platform.

Portfolio highlights

• Delabs Games — At Delabs Games, we want to create fun games that last a thousand years.
• PublicAI — PublicAI is a Web3 distributed AI training network that helps people to earn rewards by contributing data work.
• Power Protocol — Power Protocol is an infrastructure layer that drives the single, cohesive blockchain entertainment ecosystem.

Portfolio highlights

• Crowdz — Make accounts receivables a thing of the past with a competitive invoice auction for selling your invoices with invoice financing
• Glamplus — Glamplus is a SAAS-enabled beauty marketplace for salons and spas in the SMB segment. Glamplus customized to suit salon,s needs. Glamplus offers Hassle-free digital appointment tracking, invoicing, customer engagement, revenue management & much more.
• Klaar — Klaar eliminates the stress and bias of performance management with timely AI-powered insights that help teams identify areas for improvement, make data-driven decisions, and ultimately drive better performance & careers.

Portfolio highlights

• TronBank.Pro — TronBank.Pro is a DeFi platform that offers energy leasing, TRX staking, and on-chain yield optimization services via smart contracts.
• TradingRazor — TradingRazor is an AI-native trading decision and market intelligence platform engineered specifically for multi-chain cryptocurrency and decentralized finance (DeFi) markets. Rather than acting as an asset custodian or execution venue, the system serves as a predictive analytics layer that tracks fragmented on-chain capital flows, cross-marketdata, and emerging arbitrage opportunities.
• Block Security Arena — Block Security Arena is a next-generation Web3 security learning platform that leverages AI-powered quizzes, immersive hands-on Capture The Flag (CTF) challenges, and expert-led video courses to help developers, security researchers, and blockchain enthusiasts build real-world skills in identifying, understanding, and mitigating smart contract andblockchain security vulnerabilities.

Portfolio highlights

• XOCIETY — The XOCIETY metaverse is being developed by a well-established team of over 50 developers with decades of experience in the tech and web2 gaming fields.
• The FishVerse — FishVerse combines GameFi, AI, and blockchain technology, allowing players to fish in a dynamic open environment from their own homes.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• XBuild — Generate professional estimates and proposals in minutes with AI. Close deals on site. See team performance in real time. Built for contractor sales teams. Try it free.
• Eezee — Singapore’s first & largest industrial marketplace that connects local suppliers to corporate clients, leveraging technology to help both parties make informed decisions.The company offers a secure platform for buyers and sellers to transact.Our aim is to improve the efficiency of business to business (B2B) transactions. We do this byensuring that the process of selecting and purchasing your supplies becomes quicker, more convenient and transparent. We support local suppliers in establishing their presence online, enabling them to be discovered by corporate organisations.
• Vammo — Leoparda Electric is a company that manufactures electric motorcycles.

Portfolio highlights

• Spicenet — Spicenet enables universal access to the top DeFi venues across all networks, creating better financial outcomes for all.
• Real Finance — Real Finance is driven by the mission to revolutionize the financial landscape by integrating real-world assets with blockchain technology, creating a more transparent, secure, and efficient ecosystem that bridges traditional finance with decentralized innovation, enhances asset liquidity, and unlocks new opportunities for global investors.
• WorkQuest — About WorkQuest WorkQuest is a decentralized employment and workforce automation protocol enabling employers and workers to collaborate through smart contracts, stablecoin payments, AI matching engines, and on-chain reputation scoring. The platform transforms global employment into a transparent, verifiable, and borderless digital labor economy.

Portfolio highlights

• Gamium — Gamium is a Web3 and Metaverse technology company building the truly Decentralized Social Metaverse.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.
• Alliance Games — Build Beyond Limits. Multiplayer for the Next, Decentralized Era.

Portfolio highlights

• Kuri — Kuri is a healthtech company that uses AI for revenue cycle management services at hospitals, laboratories, and clinics.
• Seeri — Easy, affordable, and comprehensive: personalized catalog, sales tracking, credit, inventory management, and more, all in one place.
• 4.screen — The Driver Interaction Platform. Connect with drivers in real-time to deliver personalized and targeted campaigns.

Portfolio highlights

• Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
• Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• NEAR — NEAR is the unified commerce layer for unlocking asset liquidity and empowering agents to autonomously transact.
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• Shiden Network — Shiden Network is a multi-chain decentralized application layer on Kusama Network. Kusama Relaychain does not support smart contract functionality by design - Kusama Network needs a smart contract layer. This is where Shiden Network comes in. Shiden supports Ethereum Virtual Machine, WebAssembly, and Layer2 solutions from day one. The platform supports various applications like DeFi, NFTs and more.

Portfolio highlights

• PERL.eco — The Planetary Ecosystem Registration Ledger will be a dedicated blockchain for real-world ecological assets through tokenizing carbon credits and biodiversity, NFTs and decentralised (DeFi) rewards.
• Meter.io — Meter.io is a base layer hybrid consensus protocol built to address the volatility, scaling and interoperability problems in the existing cryptocurrencies.
• Injective — Explore Injective: the high-performance blockchain powering decentralized finance, governance, and next-gen Web3 apps with unmatched speed and scale.

Portfolio highlights

• Wicrypt — Wicrypt is a dynamic organization that consistently allows its users to get paid by sharing their Wi-Fi.
• Gamic — Gamic is a community communication/collaboration app for gamers, creators, and web3 enthusiasts.The platform combines the advantages of blockchain technology with the conventional web2 community setup, creating a seamless environment where users can interact and enjoy the benefits of web3 advancements. This simplifies the process for web2communities to access and leverage the latest blockchain technology innovations, eliminating the need to navigate across various platforms.Today, the user experience is poor for online communities trying to engage with Web3 products and services because users are required to jump across different platforms. Sharing, trading, or managing Web3 assets on most traditional communication and social apps is hard. Addressing this is crucial because Web3 access means financial freedom and opportunity for many all around the world, especially in Africa. Gamic’s central mission is to encourage blockchain adoption as a means to improve the socio-economic opportunities available to global communities. We enable users to communicate and operate in the same place, with increased security and better monetisation opportunities.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• 375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
• XTAO — XTAO's objective is to accelerate the development and use of decentralized AI.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• Mudafy — Mudafy is a tech-enabled real estate broker for LatAm.
• AgentPhone — AgentPhone is an AI and telecommunications company providing phone numbers, SMS messaging, and voice calling APIs for AI agents.
• Callab AI — Clusterlab is an AI company creating smart voice agents that automate business calls like routing, bookings, outreach, and follow-ups. Integrated with CRMs and phone systems, our solution cuts costs and enhances customer experience for modern businesses.

Portfolio highlights

• AHAlife — AHAlife is a fashion-based e-commerce platform connecting designers, brands, and publishers to individuals. The company's mission is to connect the best the world has to offer with discerning individuals from around the world. It is a discovery shopping destination for curated lifestyle products that span design, technology, fashion, media,food, beauty, and travel. Its platform sits at the intersection of content, commerce, and curation.
• Greenphire — Greenphire is the leading provider of global financial lifecycle management solutions for clinical trials, delivering the most complete data and workflow automation from budgeting through analysis to drive unprecedented business insight and smarter trials.Since 2008, we have continued to set the standard for regulated global payment workflowautomation in clinical trials. The choice of industry leaders worldwide, Greenphire delivers proven performance, resulting in more efficient and more successful trials.
• Meteor Entertainment — Meteor Entertainment engages in developing and publishing video games. The company was incorporated in 2011 and is based in Seattle, Washington.

Portfolio highlights

• Hybrid — Hybrid is a fintech company that offers a decentralized central AI tool with Web3's ecosystem of AI experts, agents, and data.
• Ajuna Network — Ajuna Network is a decentralized ecosystem for gamers and creators.
• Liquorice — Liquorice is a developer of a DeFi protocol that combines one-sided loan pools with a MEV-free trading engine.

Portfolio highlights

• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Hashflow — Tight spreads. Zero slippage. MEV-resistant.
• Joystream — Joystream is a block chain-based, decentralized video platform.

Portfolio highlights

• Biconomy — Blockchain transactions made simple. Enable Gasless meta-transactions, instant cross-chain transfers, easy layer 2 onboarding & zero failed transactions
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.
• Composable Finance — Composable is a hyper liquidity infrastructure layer for DeFi assets powered by Layer 2 Ethereum and Polkadot.