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Top 30 Blockchain Startup Investors in Panama in January 2025

Last updated: Jan 2025 A list of 30 angel investors and VC (Venture Capital) funds that invest in Blockchain startups based in Panama. We rank investors based on the number of investments they made in Blockchain companies from Panama. We update this investor list every month.

Top 30 Blockchain Startup Investors in Panama in January 2025

Investor	Blockchain Panama investments
D1 Ventures	3
Morningstar Ventures	3
Animoca Brands	2
Loren Roosendaal	2
Infinity Ventures Crypto	2
M. H. Carnegie & Co.	2
SevenX Ventures	2
Huobi Ventures	2
ROK Capital	2
Ghaf Capital	2
Kieran Warwick	1
Mechanism Capital	1
MonkeVentures	1
Aquanow	1
Ghaf Capital Partners	1
White Star Capital	1
Arca	1
Danish Chaudhry	1
GateCap Ventures	1
Varys Capital	1
MoonBoots Capital	1
Eden Holdings	1
Richard Ma	1
Ascensive Assets	1
Nayt Technologies	1
Akatsuki Games Inc.	1
InnMind	1
SkyVision Capital	1
Genblock Capital	1
Einsvill Labs	1

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Investor list

Powering the Future of Open Economy

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

The Arena — Arena. social is a cutting-edge SocialFi platform that is revolutionizing how content producers interact, network, and make money from their work.
Vistara Labs — Hardware Availability Layer
Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

We are a proprietary investment firm focused on digital assets and blockchain technology, primarily focused on the Elrond Ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Germany

Portfolio highlights

Nexio — Nexio is a bitcoin scaling solution platform that helps to improve cryptocurrency's scalability by using parallelizing Bitcoin rollouts.
KIP Protocol — KIP Protocol is a decentralised AI framework unlocking digital property rights of Knowledge Assets in the AI-powered future.
COTI AI Agents — COTI AI Agents is an AI Agent platform on the COTI network that focuses on privacy and ease of use. Users can launch, train, and trade AI agents with just one click. Co-own agents to earn revenue share while enjoying personalized tools, fun interactions, and rewards.COTI AI Agents is the first grantee of MomentumX Accelerator - The #1 acceleratorfor startups exploring Web3 privacy, backed by COTI network & Poolz.

Animoca Brands is a metaverse and gaming venture capital firm that focuses on driving digital property rights to gamers and internet users through NFTs. It utilizes gamification and blockchain to develop and market a portfolio of mobile applications, games, and additional products oriented to educational learning to ensure transparency, security,and new business models.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

FLock.io — FLock.io aims to build a decentralised privacy-preserving solution for Artificial Intelligence.
Bounty Bay — Bounty Bay is a social commerce company.
Lava Network — Lava Network aims to be a marketplace for blockchain data.

Loren Roosendaal is the Founder and Chairman of Knowingo.

Investment focus

eSports, Blockchain, Online Games
Seed, Funding Round
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Who we are We are investors and entrepreneurs helping define the next generation of Blockchain startups. Our Focus Passionate founders. Disruptive models. Borderless markets. Exponential effects. Our Geography Starting from...

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, Philippines

Portfolio highlights

GAIB — GAIB is the economic foundation for the future of artificial intelligence and computers. GAIB is a crypto-AI platform under development that tokenize GPUs, making AI computing—the processing power required to train and run AI models—more accessible.
Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
Fluid Protocol — Fluid Protocol is a decentralized, over-collateralized lending mechanism designed especially for Fuel Network. In order to maximize capital efficiency, Fluid offers users a safe and effective method of releasing liquidity from their collateral without having to liquidate their underlying assets.

M.H. Carnegie & Co. was launched by Mark Carnegie in 2010 with total equity commitments of $132 million to capitalise on the post financial crisis environment in the Australian market for smaller alternative investment opportunities. M.H. Carnegie & Co. was launched with a focus and expertise in expansion capital, as well as operating realestate.

Investment focus

Medical Device, Health Care, Medical
Series B, Seed, Series A
United States, Panama

Portfolio highlights

EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

SevenX Ventures is a Research-driven Crypto Venture Capital founded in 2020.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
PumpBTC — PumpBTC is a liquid staking protocol that aims to help Bitcoin holders to stake their bitcoins and earn yield while bolstering the security.
StakeStone — StakeStone is the best yield-bearing ETH with a decentralized yield optimizing service ready for mass adoption on layer2s.

Huobi Ventures is a venture capital firm which focuses on projects related to blockchain technology, crypto assets, and digital currency.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

0XVM — 0xVM is a Infrastructure of rollup L2s in Bitcoin. And it's an EVM-compatible execution layer on Bitcoin. It brings Bitcoin to the next level by enabling Turing-complete smart contracts. 0xVM operates directly within Bitcoin's consensus layer, integrating an execution layer and a data consistency layer. By offering a platform forprogrammability on Bitcoin, 0xVM resonates with the BTC community's vision and principles and offers a scaling approach that enhances Bitcoin's utility while retaining its integrity.
SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
Sophon — A new era of entertainment. Onchain.

ROK Capital is a multi-strategy hedge fund and accelerator aiming to grow the Korean crypto ecosystem.

Investment focus

Blockchain, Financial Services, Gaming
Seed, Series A, Funding Round
United States, Japan, Brazil

Portfolio highlights

Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
Snackclub — Learn more about play to earn games

Investment, M&A, Equity Capital, Debt Capital, Growth Capital, and VC Advisory Services.

Investment focus

Blockchain, eSports, Online Games
Seed, Funding Round
Kenya, Panama, United Arab Emirates

Portfolio highlights

myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Kieran Warwick Co-Founder at Illuvium

Investment focus

Cryptocurrency, Blockchain, Financial Services
Seed, Pre-Seed
United States, Canada, Panama

Portfolio highlights

Parcel — Parcel is on a mission to empower people with the tools they need to find their home in the metaverse. Born out of an industry that was scattered and lacked transparency, Parcel developed the first comprehensive marketplace tailored exclusively for virtual real estate. By aggregating digital land listings and fostering connection between landownersand creators, Parcel offers the full suite of services needed to build a thriving metaverse community and economy.
Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.

Mechanism Capital is an investment firm that invests in the cryptocurrency industry with a focus on decentralized finance or DeFi.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

DeFi.app — DeFi.app helps to make DeFi trading easier while keeping full ownership of crypto assets. It also helps to manage CEFI and DEFI more effectively.
Nectar AI — Nectar AI is a virtual AI companion platform that offers users the ability to create and interact with the digital customized personalities and companions.
Exponent Finance — Exponent Finance is a Solana Network DeFi fixed price market that creates time-locked tokens that can generate set returns or be traded for yield.

MonkeVentures is a venture capital firm.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed
Switzerland, United States

Portfolio highlights

Elusiv — Elusiv offers compliance in mind with next-generation privacy solutions for a better Web3.
TipLink — TipLink helps send crypto with a link. Someone with crypto can create a account and send that link to anyone over any platform. It’s like buying a gift card, connect the client's crypto wallet of choice and create a account by depositing how much they want to send.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Aquanow is a leading infrastructure and liquidity provider that enables institutional and enterprise use-cases for digital assets. Each month, billions of dollar value pass through our platform enabling a broad range of financial services for our clients. From our offices in Canada and Hong Kong, we serve an international customer base thatincludes the world’s fastest-growing financial institutions, internet platforms, and progressive businesses.Aquanow is privately funded, and guided by experienced financial executives and professional traders.

Investment focus

Apps, Web3, Gaming
Seed
Canada

Portfolio highlights

Tevaera — Tevaera is a ZK Stack powered gaming ecosystem for effortlessly launching and playing web3 games.
Accountable — Verifiable Yield Opportunities
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

GHAF Capital Partners is one of the first locally managed blockchain private investment firm based in Dubai, U.A.E.

Investment focus

Blockchain, Cryptocurrency, Finance
Seed, Funding Round, Pre-Seed
United States, India, Canada

Portfolio highlights

Nibiru Chain — Nibiru is a smart contract ecosystem with a high-performance, EVM-equivalent execution layer. Nibiru is engineered to meet the growing demand for versatile, scalable, and easy-to-use Web3 applications.
Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
Pixelverse — Pixelverse is a blockchain-based, pixelated P2E game.

Our presence, perspective and people enable us to partner closely with founders to help them define this future.

Investment focus

FinTech, Software, Financial Services
Series A, Seed, Series B
United States, Canada, United Kingdom

Portfolio highlights

Dfns — Supercharge your platform with keyless custody as a service. One API to generate secure wallets, manage your crypto, sign transactions, set up business rules, monitor security, and more.
Petfolk — Petfolk's world-class animal hospitals & pet care centers offer virtual, in-person & urgent veterinary care with a pet-parent-focused approach. Learn more!
Autoverse Studios — Autoverse Studios offers Auto Legends, a competitive social auto racing game, focusing on car culture and player engagement, offering a multi-platform experience for real-time tuning and customization.

Invest confidently in crypto assets with Arca-- an asset management firm offering institutional-caliber products for sophisticated investors.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, United Kingdom, Brazil

Portfolio highlights

375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
Moku — Moku is a web3 gaming platform that enables players connect to gaming guilds, NFT casting pages, game strategy communities, and more.
Skyfire Systems — Skyfire, a financial stack designed to enable autonomous agentic AI commerce, is to establish the first fully autonomous, open agentic AI economy in history.

Danish Chaudhry is a GP & Co-Founder at Paper Ventures.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Funding Round, Pre-Seed
United States, India, Canada

Portfolio highlights

DAM — DAM is a protocol for creating purchasing power from cross-chain token portfolios through dPRIME, a Dotsama-based stablecoin.
EclipseFi — EclipseFi is a Cosmos modular multi-chain token issuance platform that seeks to tackle Launchpad's cross-chain user experience and sustainability challenges with features like smart accounts and cross-chain design.
Altitude — Actively managed collateralised loans

GateCap Ventures investing in early-stage companies building the infrastructure for the digitization of traditional financial assets. The firm draws on a 20+ year history of managing and advising multi-billion dollar private equity portfolios for large institutional investors. It was founded in 1998.

Investment focus

Banking, FinTech, Blockchain
Series B
United States

Portfolio highlights

Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Varys Capital is a total return fund providing secure access to the digital asset class through its dual approach to investment returns in venture capital.

Investment focus

Blockchain, Software, FinTech
Seed, Pre-Seed, Initial Coin Offering
Spain, Panama, Bulgaria

Portfolio highlights

tread.fi — Explore tread.fi's institutional-grade trading platform designed to seamlessly integrate into your workflow, automate trade execution, and minimize slippage. Learn more.
Ledger Works — Blockchain consumers face significant and increasing cyber-crime. And Web3 security efforts focus on DeFi providers, not retail users. A crypto account holder should be able to receive the same fraud alerts and protection they have come to expect from their bank or credit card accounts. Our service provides account notification and cyber-crimeprotection to Crypto account holders.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

MoonBoots Capital, we add value, capital, and community to the most innovative decentralized blockchain technologies and projects.

Investment focus

Cryptocurrency, Blockchain, Online Games
Seed, Funding Round
United Kingdom, Panama, Singapore

Portfolio highlights

Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Eden Holdings operates as a venture capital firm.

Investment focus

eSports, Blockchain, Online Games
Seed
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Richard Ma is the Founder and CEO of Quantstamp.

Investment focus

Blockchain, Financial Services, Internet
Seed, Series A, Funding Round
United States, Singapore, India

Portfolio highlights

DuelNow — DuelNow offers bookie-free sports betting. At DuelNow you can create crypto bets, set your odds, and win on your terms.
RiskLayer — RiskLayer is an economic security middleware for DeFi and providing services and validating Creating positive feedback loops.
Peach Worlds — The Only No-Code Builder for Extraordinary 3D Websites. Empowering designers to create stand out and premium 3D Sites without any coding.

Ascensive Assets is a seed-stage venture firm that invests in blockchain-enabled companies across the full spectrum of web3.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Brazil

Portfolio highlights

StripChain — Stripchain is an intent-based interoperability standard that enables chain abstraction.
Nest Wallet — A Wallet Built for Traders
Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

Nayt Technologies Quantitative trading company.

Investment focus

Finance, Lending, Software
Series A
Panama

Portfolio highlights

Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Akatsuki offers MobileSocialGame services. They utilize cutting edge technology and ideas to realize and deliver their ambitions to their users. They provide new value to society through the services we manage daily. Providing services throughout the world that brighten up everyone's daily lives.

Investment focus

Media and Entertainment, Gaming, Content
Seed, Funding Round, Corporate Round
Japan, India, United States

Portfolio highlights

Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
Stems Labs — community and platform for collaborative creativity
MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Deal-origination and data intelligence platform for startup founders and VC investors in web 3.0, crypto, blockchain verticals

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed
Panama

Portfolio highlights

Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

SkyVision Capital (SVC) promotes new, open decentralized technology and its development. We are a Crypto Fund that is dedicated to incubating and investing in founders of tomorrow, today.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

Demether — Demether is a DeFi protocol that works to enable zero-cost access to TVL for blockchains.
Amnis Finance — Amnis Finance is a staking technology built on the Aptos blockchain. It is the game-changing liquid staking solution that offers a simple way to earn rewards on your APT tokens. By staking with Amnis, your tokens remain liquid and may be utilized in a variety of DeFi applications, earning additional incentives.
Nexus Interactive — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Genblock Capital invests exclusively in blockchain and cryptocurrency, with a focus on decentralized finance.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Pre-Seed
United States, Singapore, Switzerland

Portfolio highlights

OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
AINN Layer2 — A Bitcoin Layer2 Solution Built On AI-Driven Modular Architecture
Sanctum — Sanctum offers the ability to launch millions of new LSTs utilizing solana.

An invesment fully drive into blockchain technology in Defi, SosialFi, GameFi, MachineFi, Web3 and all related in crypto

Investment focus

Blockchain, Cryptocurrency, Developer Platform
Seed, Funding Round, Secondary Market
Panama, United States

Portfolio highlights

NEAR — NEAR is the chain abstraction stack, empowering builders to create apps that scale to billions of users and across all blockchains.
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
Shiden Network — Shiden Network is a multi-chain decentralized application layer on Kusama Network. Kusama Relaychain does not support smart contract functionality by design - Kusama Network needs a smart contract layer. This is where Shiden Network comes in. Shiden supports Ethereum Virtual Machine, WebAssembly, and Layer2 solutions from day one. The platform supports various applications like DeFi, NFTs and more.

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