Top 25 eSports Startup Investors in Panama (October 2026)

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Rivalz Network — Join the connectivity infrastructure between AI Agents, DeFAI and Markets.
• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• OP_NET — OPNET is a Bitcoin Layer 1 metaprotocol that enables smart contracts to function directly on the Bitcoin blockchain, without the use of sidechains or Layer 2 solutions.
• Watch.fun — Watch.fun is a platform that offers ticket-based entries for luxury watch giveaways.
• Space — Space is a leveraged prediction market platform built on Solana, designed to reward users for accurate insights while enabling efficient capital flow through competitive forecasting, combining high-performance blockchain infrastructure with advanced market mechanisms to create a transparent, scalable, and engaging environment for decentralizedprediction and informed decision-making.

Portfolio highlights

• Quotr.ai — Quotr.ai is the all-in-one pre-construction engine built to bridge the costly "takeoff-to-transaction" gap for modern subcontractors, contractors and developers. The San Francisco-based platform serves every construction trade by consolidating fragmented workflows into a single workspace. Instead of bouncing between disjointed tools,users can seamlessly transition from advanced AI takeoffs and estimates to competitive bidding, material procurement, and developer proformas. To directly improve project margins, Quotr.ai integrates dynamic material list matching, connecting users with diverse suppliers to source materials cheaper and faster. Quotr.ai enables teams to slash material costs by up to 40% and cut estimation time by 90%, bringing modern, high-ROI software to one of the world's largest industries. Backed by Llama Ventures, Quotr.ai is rapidly becoming the platform of choice for forward-thinking construction firms with a mission to make pre-construction faster, easier, and more accurate.
• AEON — AEON is a crypto payment framework designed for AI-driven and real-world transactions. It supports omni-chain payments across ecosystems like EVM, SVM, and TON, enabling seamless cross-chain usage. Its solutions include AI-powered payments, Web3 online and mobile payments, QR/contactless acceptance, and swap pay, all designed to simplifyadoption for users and merchants.
• KOR Protocol — KOR Protocol is a decentralized intellectual property (IP) infrastructure designed to empower creators, protect rights, and enable seamless collaboration and monetization of IP assets across various industries, including music, film, TV, gaming, and art. Backed by notable entities like Animoca Brands, Republic, Niantic, Sfermion, Solana, andprominent creators such as Black Mirror, Disclosure, deadmau5, and Richie Hawtin, KOR leverages blockchain, AI, and DeFi to offer a transparent, efficient, and scalable environment for IP expansion.

Portfolio highlights

• SnakeLite — Predict the performance of Hyperliquid traders, track the flow of smart funds, and earn profits in the decentralized prediction market through AI signals and real-time data.
• Sophon — Soph(+) is a tech studio building novel consumer experiences in crypto and ai. we build, own, and ship our own products, starting with pyre.
• A.A.A C(H+A)RM — AAA C(H+A)RM (Autonomous AI Agents Launchpad & Layer3) is the first AI-first, agent-focused orchestration platform.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Sumer Money — Sumer Money is a cross-chain synthetic assets protocol that enables composable Defi across blockchains.
• SYNTRA — Syntra is an AI-driven trading infrastructure company focused on disciplined execution, real-time risk management, and transparent market operations in digital asset markets. The company builds systems that monitor market structure, volatility, liquidity, and correlation dynamics, enabling automated decision-making with strict risk controls.Syntra’s infrastructure is designed to prioritize execution quality, capital preservation, and operational transparency over short-term performance optimization.Syntra operates a live execution environment where all system actions are observable in real time, providing an open view into how the trading system behaves across different market conditions. The platform is infrastructure-first, emphasizing robustness, scalability, and controlled growth rather than aggressive user acquisition. The company is currently focused on expanding its execution stack, data pipelines, and risk management framework to support broader market coverage and institutional-grade reliability.

Portfolio highlights

• myco — Stream English Premier League, live cricket, international TV channels, web series, movies from Hollywood, Bollywood, Turkish, Irani, and Pakistani dramas.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Wizzwoods — 1st pixel farm game integrates interchain capabilities with a SocialFi twist.
• SuperIntent — Discover intelligent crypto investing with SuperIntent. Supercharged by DeFAI, it's your all-in-one app for smarter strategies and stress-free asset management.
• SuperGaming — At SuperGaming, we are putting India on the global gaming map.

Portfolio highlights

• Superlogic — OneOf is the mass-consumer Web3 company connecting the next 100M non-crypto-native fans to iconic brands, artists, and athletes. OneOf technology enables global brands and enterprises to reimagine commerce, loyalty and engagement, allowing consumers to seamlessly collect or trade digital assets with no prior crypto expertise. Deeply committed to a sustainable and inclusive blockchain future, minting digital assets on OneOf's platform uses up to 2 million times less energy than previous generation proof-of-work networks, and costs up to 99% less in gas fees. A leader in diversity, over 80% of the collections curated by OneOf come from minority or female creators.
• PERPTools — PERPTools combines crypto perpetual trading with activity points and risk-free market predictions.
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.

Portfolio highlights

• Hemi Labs — Hemi builds Bitcoin infrastructure for money that can be moved, programmed and put to work.
• Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• 5ire — 5ire is a blockchain network that brings sustainability, technology, and Innovation to build the 5th industrial revolution (5IR). The mission of the 5ire ecosystem is to embed the for-benefit paradigm at the heart of the blockchain, highly incentivize practices that align with the United Nations Sustainable Development Goals (SDGs), facilitate thetransition from the 4IR to 5IR and accelerate the implementation of the UN 2030 Agenda for Sustainable Development. The company's primary offering is 5ireChain, a layer one, sustainability-driven 5th generation blockchain that ensures adherence to the philosophy of 5IR, creating a net positive impact on the planet and serving humanity.
• Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Meta Pool — Meta Pool DAO builds, runs infrastructure, and incubates projects through a milestone-based program.
• Amnis Finance — Stake APT on the best liquid staking protocol on Aptos to receive daily rewards with an attractive APR of 2%.
• Velvet Capital — Velvet Capital is a DeFi operating system that helps launch and manage on-chain funds and structured products. Velvet Capital offers its users a way to gain exposure to digital assets.

Portfolio highlights

• 375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
• XTAO — xTAO Inc. (TSXV: XTAO.U, OTC: XTAIF) is a public company building the infrastructure for open, decentralized AI on Bittensor.
• Agentum — Agentum provides an autonomous economic layer built on the BNB Chain that enables AI agents to transact trustlessly with one another without human intervention. The protocol utilizes a combination of TEE confidential computing, zkVM verifiable evaluation, and specialized ERC standards to ensure secure task execution, portable agent reputations, andautomated escrow settlements. By aligning economic incentives at the protocol layer, it ensures that honest machine-to-machine commerce always carries higher payoffs than deceptive practices.

Portfolio highlights

• Kapkap — KAPKAP x PISCES88 menghadirkan akses APK Slot88 online dengan koleksi permainan dari berbagai provider dalam satu platform. Nikmati pilihan game yang beragam, tampilan responsif, akses praktis melalui perangkat mobile, serta informasi permainan terbaru.
• SuperIntent — Discover intelligent crypto investing with SuperIntent. Supercharged by DeFAI, it's your all-in-one app for smarter strategies and stress-free asset management.
• Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Portfolio highlights

• BAYZ — NFT Gaming Startup | Esports & Content Community HUB | #PlayToEarn
• UNXD — UNXD is a curated NFT marketplace for the best of digital luxury and culture. Featuring NFTs from Dolce&Gabbana, Jacob & Co., and more.
• Mon Studios — An indie game development studio

Portfolio highlights

• Capx — Run a company from your terminal. Casa, Launchpad, Terminal.
• Noodles Finance — The no-brainer trading platform for Sui.
• YOAKE Entertainment — YOAKE Entertainment is a music studio that specializes in the planning, production, and development of entertainment content.

Portfolio highlights

• Delabs Games — At Delabs Games, we want to create fun games that last a thousand years.
• PublicAI — PublicAI is a Web3 distributed AI training network that helps people to earn rewards by contributing data work.
• Power Protocol — The ecosystem for blockchain entertainment. Fueled by $POWER. Launch Partner: @Fableborne Power Up Your Play

Portfolio highlights

• OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
• AINN Layer2 — AINN Layer2 is a decentralized Bitcoin Layer2 network development.It promotes large-scale AI applications
• Sanctum — Stake SOL and earn optimized LST returns from JupSOL, bbSOL, and more, and launch your own custom LST and Solana validator.

Portfolio highlights

• Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
• Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.
• Layer Social Labs — A home for global companionship and endless entertainment. Post More, Play More, Earn More.

Portfolio highlights

• Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
• Stems Labs — community and platform for collaborative creativity
• MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Portfolio highlights

• Nexio — Making Bitcoin Productive
• Turtle Club — Aggregated, diligenced, personalized onchain yield management.
• Neutral Trade — Where allocators source strategies and traders raise capital. Institutional-grade quant vaults on-chain.

Portfolio highlights

• Pixelverse — 30M+ players. Meme IP integrations. Pixelverse is scaling Telegram-native games into a social, competitive platform economy.
• Mavryk Dynamics — Mavryk Dynamics simplifies trading real-world assets (RWA) and using decentralized finance (DeFi).
• Swarm Network — Swarm Network is a decentralized network for owning, controlling, and monetizing AI agents.

Portfolio highlights

• StripChain — A full-stack, intent-based interoperability protocol for omnichain apps. Connecting 13+ blockchains through StripChain's unified interoperability layer.
• Nest Wallet — A Wallet Built for Traders
• Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

Portfolio highlights

• Play AI — The Orchestration Layer for Crypto x AI
• Metagood — Metagood is the operating layer for tokenized assets across their full lifecycle: compliance, transfer rules, entitlements, corporate actions, and audit.
• VOYA Games — Voya Games is a Berlin-based game development studio. The company focuses on creating a network of interconnected Web3 games centered around player ownership and tokenized economies. Their flagship title, Craft World, is a casual resource management game set in a post-apocalyptic world where players collaborate with friendly dinosaurs to rebuildcivilization. Craft World integrates blockchain features such as NFTs and a utility token called Dyno Coin, enabling players to own, trade, and participate in a decentralized game economy.