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Top 25 Blockchain VC (Venture Capital) Funds in Panama in January 2025

Last updated: Jan 2025 A list of 25 VC (Venture Capital) funds that invest in Blockchain startups based in Panama. We rank investors based on the number of investments they made in Blockchain companies from Panama. We update this investor list every month.

Top 25 Blockchain VC (Venture Capital) Funds in Panama in January 2025

Investor	Blockchain Panama investments
D1 Ventures	3
Morningstar Ventures	3
ROK Capital	2
Infinity Ventures Crypto	2
M. H. Carnegie & Co.	2
Ghaf Capital	2
SevenX Ventures	2
Huobi Ventures	2
Animoca Brands	2
Genblock Capital	1
Arca	1
Mechanism Capital	1
GateCap Ventures	1
Varys Capital	1
Yield Guild Games	1
MonkeVentures	1
White Star Capital	1
Ascensive Assets	1
MoonBoots Capital	1
Akatsuki Games Inc.	1
Eden Holdings	1
Aquanow	1
InnMind	1
Ghaf Capital Partners	1
Nayt Technologies	1

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Investor list

Powering the Future of Open Economy

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

The Arena — Arena. social is a cutting-edge SocialFi platform that is revolutionizing how content producers interact, network, and make money from their work.
Vistara Labs — Hardware Availability Layer
Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

We are a proprietary investment firm focused on digital assets and blockchain technology, primarily focused on the Elrond Ecosystem.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Germany

Portfolio highlights

Nexio — Nexio is a bitcoin scaling solution platform that helps to improve cryptocurrency's scalability by using parallelizing Bitcoin rollouts.
KIP Protocol — KIP Protocol is a decentralised AI framework unlocking digital property rights of Knowledge Assets in the AI-powered future.
COTI AI Agents — COTI AI Agents is an AI Agent platform on the COTI network that focuses on privacy and ease of use. Users can launch, train, and trade AI agents with just one click. Co-own agents to earn revenue share while enjoying personalized tools, fun interactions, and rewards.COTI AI Agents is the first grantee of MomentumX Accelerator - The #1 acceleratorfor startups exploring Web3 privacy, backed by COTI network & Poolz.

ROK Capital is a multi-strategy hedge fund and accelerator aiming to grow the Korean crypto ecosystem.

Investment focus

Blockchain, Financial Services, Gaming
Seed, Series A, Funding Round
United States, Japan, Brazil

Portfolio highlights

Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
GAM3S.GG — Your home of web3 gaming offering game discovery, reviews, guides, news & quests for a full experience.
Snackclub — Learn more about play to earn games

Who we are We are investors and entrepreneurs helping define the next generation of Blockchain startups. Our Focus Passionate founders. Disruptive models. Borderless markets. Exponential effects. Our Geography Starting from...

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, Philippines

Portfolio highlights

GAIB — GAIB is the economic foundation for the future of artificial intelligence and computers. GAIB is a crypto-AI platform under development that tokenize GPUs, making AI computing—the processing power required to train and run AI models—more accessible.
Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
Fluid Protocol — Fluid Protocol is a decentralized, over-collateralized lending mechanism designed especially for Fuel Network. In order to maximize capital efficiency, Fluid offers users a safe and effective method of releasing liquidity from their collateral without having to liquidate their underlying assets.

M.H. Carnegie & Co. was launched by Mark Carnegie in 2010 with total equity commitments of $132 million to capitalise on the post financial crisis environment in the Australian market for smaller alternative investment opportunities. M.H. Carnegie & Co. was launched with a focus and expertise in expansion capital, as well as operating realestate.

Investment focus

Medical Device, Health Care, Medical
Series B, Seed, Series A
United States, Panama

Portfolio highlights

EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Investment, M&A, Equity Capital, Debt Capital, Growth Capital, and VC Advisory Services.

Investment focus

Blockchain, eSports, Online Games
Seed, Funding Round
Kenya, Panama, United Arab Emirates

Portfolio highlights

myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

SevenX Ventures is a Research-driven Crypto Venture Capital founded in 2020.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Funding Round
United States, Singapore, United Kingdom

Portfolio highlights

Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
PumpBTC — PumpBTC is a liquid staking protocol that aims to help Bitcoin holders to stake their bitcoins and earn yield while bolstering the security.
StakeStone — StakeStone is the best yield-bearing ETH with a decentralized yield optimizing service ready for mass adoption on layer2s.

Huobi Ventures is a venture capital firm which focuses on projects related to blockchain technology, crypto assets, and digital currency.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Initial Coin Offering
United States, Singapore, United Kingdom

Portfolio highlights

0XVM — 0xVM is a Infrastructure of rollup L2s in Bitcoin. And it's an EVM-compatible execution layer on Bitcoin. It brings Bitcoin to the next level by enabling Turing-complete smart contracts. 0xVM operates directly within Bitcoin's consensus layer, integrating an execution layer and a data consistency layer. By offering a platform forprogrammability on Bitcoin, 0xVM resonates with the BTC community's vision and principles and offers a scaling approach that enhances Bitcoin's utility while retaining its integrity.
SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
Sophon — A new era of entertainment. Onchain.

Animoca Brands is a metaverse and gaming venture capital firm that focuses on driving digital property rights to gamers and internet users through NFTs. It utilizes gamification and blockchain to develop and market a portfolio of mobile applications, games, and additional products oriented to educational learning to ensure transparency, security,and new business models.

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, United Kingdom

Portfolio highlights

FLock.io — FLock.io aims to build a decentralised privacy-preserving solution for Artificial Intelligence.
Bounty Bay — Bounty Bay is a social commerce company.
Lava Network — Lava Network aims to be a marketplace for blockchain data.

Genblock Capital invests exclusively in blockchain and cryptocurrency, with a focus on decentralized finance.

Investment focus

Blockchain, Cryptocurrency, Financial Services
Seed, Funding Round, Initial Coin Offering
United States, Singapore, Switzerland

Portfolio highlights

OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
Root Protocol — Root is building an operating system with the composition of an intent-centric aggregator of digital identity, virtual accounts, social graphs, and more to enable unified access to Web3.
BitFlow Finance — The decentralized exchange for Bitcoiners. Bitflow Foundation supports the governance and growth of the Bitflow DeFi Protocol.

Invest confidently in crypto assets with Arca-- an asset management firm offering institutional-caliber products for sophisticated investors.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, United Kingdom, Brazil

Portfolio highlights

375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
Moku — Moku is a web3 gaming platform that enables players connect to gaming guilds, NFT casting pages, game strategy communities, and more.
Skyfire Systems — Skyfire, a financial stack designed to enable autonomous agentic AI commerce, is to establish the first fully autonomous, open agentic AI economy in history.

Mechanism Capital is an investment firm that invests in the cryptocurrency industry with a focus on decentralized finance or DeFi.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Canada

Portfolio highlights

DeFi.app — DeFi.app helps to make DeFi trading easier while keeping full ownership of crypto assets. It also helps to manage CEFI and DEFI more effectively.
Nectar AI — Nectar AI is a virtual AI companion platform that offers users the ability to create and interact with the digital customized personalities and companions.
Exponent Finance — Exponent Finance is a Solana Network DeFi fixed price market that creates time-locked tokens that can generate set returns or be traded for yield.

GateCap Ventures investing in early-stage companies building the infrastructure for the digitization of traditional financial assets. The firm draws on a 20+ year history of managing and advising multi-billion dollar private equity portfolios for large institutional investors. It was founded in 1998.

Investment focus

Banking, FinTech, Blockchain
Series B
United States

Portfolio highlights

Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Varys Capital is a total return fund providing secure access to the digital asset class through its dual approach to investment returns in venture capital.

Investment focus

Blockchain, Software, FinTech
Seed, Pre-Seed, Initial Coin Offering
Spain, Panama, Bulgaria

Portfolio highlights

tread.fi — Explore tread.fi's institutional-grade trading platform designed to seamlessly integrate into your workflow, automate trade execution, and minimize slippage. Learn more.
Ledger Works — Blockchain consumers face significant and increasing cyber-crime. And Web3 security efforts focus on DeFi providers, not retail users. A crypto account holder should be able to receive the same fraud alerts and protection they have come to expect from their bank or credit card accounts. Our service provides account notification and cyber-crimeprotection to Crypto account holders.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Yield Guild Games (YGG) is a decentralized autonomous organization (DAO) for investing in non fungible tokens (NFTs) used in virtual worlds and blockchain-based games. The organization’s mission is to create the biggest virtual world economy, optimizing its community-owned assets for maximum utility, and sharing its profits with its token holders.

Investment focus

Gaming, Blockchain, Video Games
Seed, Funding Round, Initial Coin Offering
United States, Singapore, Australia

Portfolio highlights

LOScoin — LOScoin is a web3 gaming and social application based on telegram bot. LOScoin is committed to profoundly combining Web3's novel interactive experience with the passion of LOScoin's MEME community, creating a highly engaging, entertaining, and economically active DAO community, and providing users with a completely new gaming and socialexperience.
Party Icons — Party Icons is a web3 mobile gaming platform. Its mission is to blend the social glue of party games with the intensity of extraction shooters.
Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!

MonkeVentures is a venture capital firm.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed
Switzerland, United States

Portfolio highlights

Elusiv — Elusiv offers compliance in mind with next-generation privacy solutions for a better Web3.
TipLink — TipLink helps send crypto with a link. Someone with crypto can create a account and send that link to anyone over any platform. It’s like buying a gift card, connect the client's crypto wallet of choice and create a account by depositing how much they want to send.
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Our presence, perspective and people enable us to partner closely with founders to help them define this future.

Investment focus

FinTech, Software, Financial Services
Series A, Seed, Series B
United States, Canada, United Kingdom

Portfolio highlights

Dfns — Supercharge your platform with keyless custody as a service. One API to generate secure wallets, manage your crypto, sign transactions, set up business rules, monitor security, and more.
Petfolk — Petfolk's world-class animal hospitals & pet care centers offer virtual, in-person & urgent veterinary care with a pet-parent-focused approach. Learn more!
Autoverse Studios — Autoverse Studios offers Auto Legends, a competitive social auto racing game, focusing on car culture and player engagement, offering a multi-platform experience for real-time tuning and customization.

Ascensive Assets is a seed-stage venture firm that invests in blockchain-enabled companies across the full spectrum of web3.

Investment focus

Blockchain, Cryptocurrency, Gaming
Seed, Funding Round, Series A
United States, Singapore, Brazil

Portfolio highlights

StripChain — Stripchain is an intent-based interoperability standard that enables chain abstraction.
Nest Wallet — A Wallet Built for Traders
Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

MoonBoots Capital, we add value, capital, and community to the most innovative decentralized blockchain technologies and projects.

Investment focus

Cryptocurrency, Blockchain, Online Games
Seed, Funding Round
United Kingdom, Panama, Singapore

Portfolio highlights

Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
Planet Sandbox — Planet Sandbox is the third-person NFT sandbox game that powers players with limitless building tools to customize their own worlds and design game modes. It allows players to build and own arenas to fight other players in different game modes using their own NFT weapons and accessories.
Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Akatsuki offers MobileSocialGame services. They utilize cutting edge technology and ideas to realize and deliver their ambitions to their users. They provide new value to society through the services we manage daily. Providing services throughout the world that brighten up everyone's daily lives.

Investment focus

Media and Entertainment, Gaming, Content
Seed, Funding Round, Corporate Round
Japan, India, United States

Portfolio highlights

Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
Stems Labs — community and platform for collaborative creativity
MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Eden Holdings operates as a venture capital firm.

Investment focus

eSports, Blockchain, Online Games
Seed
Panama

Portfolio highlights

Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Aquanow is a leading infrastructure and liquidity provider that enables institutional and enterprise use-cases for digital assets. Each month, billions of dollar value pass through our platform enabling a broad range of financial services for our clients. From our offices in Canada and Hong Kong, we serve an international customer base thatincludes the world’s fastest-growing financial institutions, internet platforms, and progressive businesses.Aquanow is privately funded, and guided by experienced financial executives and professional traders.

Investment focus

Apps, Web3, Gaming
Seed
Canada

Portfolio highlights

Tevaera — Tevaera is a ZK Stack powered gaming ecosystem for effortlessly launching and playing web3 games.
Accountable — Verifiable Yield Opportunities
Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

Deal-origination and data intelligence platform for startup founders and VC investors in web 3.0, crypto, blockchain verticals

Investment focus

Blockchain, Gaming, Cryptocurrency
Seed
Panama

Portfolio highlights

Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

GHAF Capital Partners is one of the first locally managed blockchain private investment firm based in Dubai, U.A.E.

Investment focus

Cryptocurrency, Blockchain, Finance
Seed, Funding Round, Pre-Seed
India, United States, Canada

Portfolio highlights

Nibiru Chain — Nibiru is a smart contract ecosystem with a high-performance, EVM-equivalent execution layer. Nibiru is engineered to meet the growing demand for versatile, scalable, and easy-to-use Web3 applications.
Shardeum — Shardeum is an EVM-based, linearly scalable smart contract platform that maintains low gas fees while providing true decentralization and solid security
Ithaca Finance — Ithaca Finance a cross-chain derivatives trading and settlements protocol, is composed of an on-chain settlement layer with an innovative off-chain matching engine.

Nayt Technologies Quantitative trading company.

Investment focus

Finance, Lending, Software
Series A
Panama

Portfolio highlights

Blueberry Protocol — Blueberry is an interface for interacting with the rest of DeFi with the ability to leverage and hedge by borrowing from an internal lending market.

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