Top 50 SaaS Startup Investors in Panama in May 2026

Portfolio highlights

• Aark — Trade crypto perpetuals with up to 1000x leverage, zero gas fees, and an industry-low 0.01% trading fee. Earn payback on losses with VIP rewards. RWA & altcoin perps on Arbitrum. Backed by OKX Ventures.
• Itheum — As we enter the web3 and metaverse era; Itheum unlocks data silos and generates new value for your data.
• Fanable — Fanable is a Web3 marketplace specialized in Pokémon, comic books, and collectibles, allowing users to purchase, sell, and engage with their favorite products in both physical and digital forms.

Portfolio highlights

• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Joystream — Joystream is a block chain-based, decentralized video platform.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
• GAM3S.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Snackclub — Learn more about play to earn games

Portfolio highlights

• myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Metatheory — Metatheory Inc. is an interactive technology and entertainment company building Web3 games, interactive content, social experiences, and other community-driven adventures. Metatheory’s mission is to inspire imagination by connecting people worldwide through immersive worlds built on cross-generational IP.
• Pagos Solutions — Get real-time payment data detecting issues, trends, and opportunities plus intelligent payment solutions for optimizing payment performance.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
• Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.
• Eizper Chain — Eizper Chain is a blockchain action online multiplayer role-playing game that celebrates adventure and arena battle.

Portfolio highlights

• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• BluWhale — BluWhale's mission is to leverage AI and ML to allow game developers to focus on ways to improve the game rather than wrangling and making sense of astronomical amounts of data. BluWhale's smart automation will do the heavy lifting usually reserved for data analysts and data scientists all in the background, and surface actionable insight

Portfolio highlights

• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• tread.fi — Explore tread.fi's institutional-grade trading platform designed to seamlessly integrate into your workflow, automate trade execution, and minimize slippage. Learn more.
• Ledger Works — Blockchain consumers face significant and increasing cyber-crime. And Web3 security efforts focus on DeFi providers, not retail users. A crypto account holder should be able to receive the same fraud alerts and protection they have come to expect from their bank or credit card accounts. Our service provides account notification and cyber-crimeprotection to Crypto account holders.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Everlyn — Everlyn is a Web3 video AI model that generates a decentralized infrastructure layer for autonomous video.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Cold River Games — Crystalfall is an upcoming free online action RPG with customizable skills and an endless endgame, set in a steampunk world.

Portfolio highlights

• Evolv — Evolv is equipping brands with the technology to create immersive experiences for their customers.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Perena — Perena is a startup developing the basic infrastructure to address significant difficulties in the stablecoin sector.
• AlchemyNFT — AlchemyNFT is a non-fungible token (NFT) service.
• StakeStone — Discover the Autonomous Neo Bank redefining finance. Earn bank-grade yield, make borderless payments, and power intelligent money movement for humans, AI, and machines.

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
• Stems Labs — community and platform for collaborative creativity
• MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• RedStone — RedStone delivers frequently updated, reliable and diverse data for your dApp and smart contracts.

Portfolio highlights

• PACT — PACT designs Elegant materials produced in tune with the planet earth. It create revolutionary, sustainable biomaterials using the earth's resources, including collagen, herbal extracts, oils, and minerals.
• Rove — Claim your spot on the waitlist for the first ever travel credit card for Gen Z.
• Magrathea — Magrathea Metals is a mining company that unlocks centuries of growth in human civilization by reducing the socioenvironmental impacts.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• Momint — Momint is the Web3 investment platform of the future. The safest and easiest to use NFT marketplace in the world. Discover the real-world potential of NFTs.
• PropertyScout — PropertyScout is a proptech startup that builds an end-to-end rental and sale platform for owners, agents, buyers, and tenants. The startup is connecting over 1,800 agents and agencies with buyers, renters, and owners, servicing thousands of satisfied customers every month. PropertyScout leverages its database of more than 200,000 properties, itstechnology platform, and its centralized operations to digitize and automate 90% of the real estate transaction. This frees up agents’ time to professionally and efficiently communicate with buyers, renters, owners and co-agents to deliver outstanding service and close transactions faster. Providing a transparent and trusted experience, PropertyScout has quickly become the favorite go-to place for buying, selling, and renting real estate in Thailand, as proven by hundreds of five-star reviews.

Portfolio highlights

• Datagram — Datagram is an AI-driven, decentralized infrastructure platform operating as a DePIN baselayer. The company provides a live, scalable node network for launching custom DePIN networks and real-world decentralized applications, with cost savings over traditional cloud providers.
• Ooga Booga — Multichain Liquidity Aggregator
• Accountable — Accountable is the new standard for real-time financial verification. Prove assets and liabilities privately, powered by the Data Verification Network (DVN).

Portfolio highlights

• SolRazr — SolRazr is the first decentralized developer ecosystem for Solana, offering Launchpad, Accelerator, and Developer Tools.
• Exotic Markets — Exotic Markets bring wealth management and structured products out of the bank and in the decentralized finance world. Exotic Markets Maximise the investments with simple and sustainable products.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.
• TigerBeetle — TigerBeetle operates as a distributed financial accounting database for mission-critical safety and performance.

Portfolio highlights

• Caden — Caden is the world's first Zero-Party Data platform. We allow users to own and control their own personal data, make money off it, and share it with trusted consumer brands, while maintaining their privacy.
• AnthologyAI — AnthologyAI is the breakthrough Artificial Intelligence Consumer Insights & Predictions Platform with billions of real-time data sourced directly and ethically from consumers. Access previously unavailable levels of intelligence about retail spending, geolocation, media consumption, travel, ride sharing and more — in realtime, at scale.
• Vero Technologies — Vero Technologies is a Financial Services based company.

Portfolio highlights

• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Portfolio highlights

• BBy — BBy connects nursing mothers with couples who can't produce or do not produce enough breast milk to feed their child
• Careerist — Careerist is the connecting bridge between people without tech or coding background and the U.S. tech industry. We quickly train and apply our students for simple well-paid jobs like software testing, while helping them grow into more advanced roles.
• Legistify — Legistify offers AI-powered legal operations software to streamline workflows, manage contracts, track legal cases and improve productivity for enterprise legal teams

Portfolio highlights

• Bujeti — Bujeti is the finance control centre for African businesses. Manage expenses, automate payments, and issue corporate cards for total control and visibility.
• FlexDesk — FlexDesk is creating a new evolution of the flexible workspace model. Remote workers use the platform to discover and book a dedicated desk or private office by the day. FlexDesk unlocks this inventory by partnering with office landlords and coworking operators that have furnished, underutilized space.
• SearchEye — Get tech-driven SEO at scale, speed and a fraction of the cost compared to traditional agencies. Acquire PR Mentions, Digital PR and Content.

Portfolio highlights

• Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Dinari — Discover Equity Boundless - Simplify everything from equity management and options grant to payroll so that you no longer have to worry about compliance, taxes, or vesting schedules no matter where your employees are.
• BitcoinOS — BitcoinOS is a Decentralized Finance company that builds and develops Bitcoin ecosystem.

Portfolio highlights

• Aire — The income assessment platform that leverages first-party data. Access real-time confidence in the stated income of any consumer.
• Questflow — Questflow Labs seeking to give customers with an all-in-one solution for user intent perception and distribution, AI agentic workflow automation, and human-AI cooperation. Questflow Labs is pioneering a novel approach to decentralized AI agentic workflow.
• Flare — Flare equips your team to shut down cybercrime before it escalates. Detect, prioritize, and remediate external cyber threats with automated Threat Exposure Management.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• Shippify — Shippify is an innovative logistics service that connects businesses with a diverse network of drivers & 3PLs to provide same day delivery . Shippify is backed by strategic leading venture capital and angel investors. Currently available in Brasil, Mexico, Chile and Ecuador. The company was founded in 2014.

Portfolio highlights

• Splyce Finance — dETF protocol. Permissionless, on-chain index- and yield ETFs.

Portfolio highlights

• Thyme Care — Thyme Care is a dedicated team of nurses and care experts offering value-based cancer care to help you through all phases of the cancer experience.
• WelbeHealth — At WelbeHealth, we envision a world in which every human being is able to participate fully in life through their final days. We serve frail seniors through a model of comprehensive medical and social care called PACE (Program of All-Inclusive Care for the Elderly), helping our participants live better, longer, and more independently.Founded by aseasoned group of physician entrepreneurs, our leadership team hails from leading payer and provider organizations such as GoHealth Urgent Care, BAYADA Home Health, AirStrip Technologies, Evolent Health, and On Lok.With funding from leading venture capital firms, we're looking for team members who are inspired to help us deliver on our mission of unlocking the full potential of the most vulnerable seniors in our communities. Our colleagues are energized by working in diverse groups toward our shared purpose, are eager to drive groundbreaking innovations, and have the courage to care for our participants with empathy and love.
• Eleanor Health — At Eleanor Health, our mission is to help anyone concerned about their mental health or affected by addiction live amazing lives.

Portfolio highlights

• 375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
• Moku — Moku is a web3 gaming platform that enables players connect to gaming guilds, NFT casting pages, game strategy communities, and more.
• Skyfire Systems — Skyfire, a financial stack designed to enable autonomous agentic AI commerce, is to establish the first fully autonomous, open agentic AI economy in history.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Multisynq — Multisynq is a decentralized and low-latency synchronization network.
• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Elusiv — Elusiv offers compliance in mind with next-generation privacy solutions for a better Web3.
• TipLink — TipLink helps send crypto with a link. Someone with crypto can create a account and send that link to anyone over any platform. It’s like buying a gift card, connect the client's crypto wallet of choice and create a account by depositing how much they want to send.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Gata — Gata uses data technology to develop superintelligence and to ensure its alignment with human objectives.
• Algebra.Finance — Algebra.Finance is the Financial Services.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Anoma — A sovereign, proof-of-stake blockchain protocol that enables private, asset-agnostic cash and private bartering among any number of parties.
• Keplr — Introducing the first, and leading, IBC-enabled wallet for Cosmos and beyond
• Datachain — Datachain is a tech company that revolutionizes blockchain interoperability and stablecoin settlement. we aim to make it possible for the world to interact as one network, making it easier to use a variety of services.

Portfolio highlights

• Dmail — Dmail Network is a decentralized mailbox that provides a safe and private environment for users' communication, storage, tokens, and NFTs. The company was founded by Mittal S. and Lucas L. in 2021.
• OMNIA Protocol — OMNIA Protocol offers a secure and private infrastructure for accessing blockchain technology. It provides high availability RPC endpoints for Ethereum, ensuring users can connect to the blockchain without being traced or monitored. The company focuses on delivering a compliant environment for handling personal data, including blockchain addressesand transactional information. OMNIA Protocol aims to democratize access to blockchain infrastructure, challenging the current concentration of this access among a few corporations. It supports various blockchains, including Bitcoin, Binance, Avalanche, Polygon, Arbitrum, and Optimism, through its platform, offering secure Arbitrum RPC Nodes features.
• Cumulus Encrypted Storage System (CESS) — CESS revolutionizes AI, DeSci, RWA, Enterprise, and more with secure, transparent, and traceable data solutions. Delivering AI computing and data infrastructure, CESS enables data privacy and sovereignty with a focus on AI Agent applications and frameworks.

Portfolio highlights

• Caden — Caden is the world's first Zero-Party Data platform. We allow users to own and control their own personal data, make money off it, and share it with trusted consumer brands, while maintaining their privacy.
• Dashy Dash — Dashy Dash is a free community powered tool that makes it easy to manage invoices, discover new products & compare prices to help you save money.
• Vero Technologies — Vero Technologies is a Financial Services based company.

Portfolio highlights

• Sidus Heroes — gaming company
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.
• CryptoVsZombie — CryptoVsZombie is the ultimate crypto tower defence in which players are required to multitask in both offensive and defensive modes.

Portfolio highlights

• Crowdz — Make accounts receivables a thing of the past with a competitive invoice auction for selling your invoices with invoice financing
• Glamplus — Glamplus is a SAAS-enabled beauty marketplace for salons and spas in the SMB segment. Glamplus customized to suit salon,s needs. Glamplus offers Hassle-free digital appointment tracking, invoicing, customer engagement, revenue management & much more.
• Klaar — Klaar eliminates the stress and bias of performance management with timely AI-powered insights that help teams identify areas for improvement, make data-driven decisions, and ultimately drive better performance & careers.

Portfolio highlights

• Portal to Bitcoin — The only custody-less interoperability protocol for Bitcoin. Swap native BTC, Ordinals, Runes with L2s and L1s
• Acta Finance — Acta Finance develops a complete DeFi ecosystem, EVM compatible, able to deploy and integrate EVM compatible networks.
• Monarch Wallet — As part of this journey, we will discontinue our wallet services effective July 1, 2024.

Portfolio highlights

• Demole — Demole is a play to earn NFT gamification platform.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Radom — A Decentralised Network for Coordination of Cloud Applications and Connected Assets

Portfolio highlights

• XOCIETY — The XOCIETY metaverse is being developed by a well-established team of over 50 developers with decades of experience in the tech and web2 gaming fields.
• The FishVerse — FishVerse combines GameFi, AI, and blockchain technology, allowing players to fish in a dynamic open environment from their own homes.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• Gamium — Gamium is a Web3 and Metaverse technology company building the truly Decentralized Social Metaverse.
• Lympid — We believe that anyone should have access to the amazing opportunities found on the blockchain, from DeFi protocols (aave, compound, yearn…) to Crypto Indexes, there's so much to discover! At Lympid you will be able to do it all easily in the same app, and directly through EUR.
• Alliance Games — Build Beyond Limits. Multiplayer for the Next, Decentralized Era.

Portfolio highlights

• Starbots — Starbots is Solana's first-ever battle NFT game.
• Linear — Linear allows the user to manage software development and track bugs. Built for speed and efficiency.The founders started Linear from their own frustrations building software projects in successful high-growth companies like Airbnb, Coinbase and Uber. The founders wanted to create the tools that focus us and its team in making progress, not getin the way. Tools that are fast and efficient. Speed and performance were the main things Linear focuses on early on and keep focusing on that.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• ZAP — ZAP offers a reputation-based token distribution protocol that supports fair rewards for user contributions within the Blast ecosystem. It enables users to participate in various projects through missions and seamless investment options. Additionally, ZAP is expanding its services to other blockchains and developing tools to simplify access toventure-capital-backed projects.
• Galaxis — Galaxis maintains an engagement platform that aims to transform and strengthen the relationship between creators and their communities. The company's platform assists creators by injecting simple NFTs with unique utilities that can expand and alter.
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.

Portfolio highlights

• Zuki Moba — The First E-Sports Game Empowering Gamers | Zuki Moba
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.

Portfolio highlights

• Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
• Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.
• Layer Social Labs — A home for global companionship and endless entertainment. Post More, Play More, Earn More.