Top 20 Hardware Startup Investors in Panama (October 2026)

Portfolio highlights

• Hawksight — Hawksight provides a protocol that optimizes yield on Solana DeFi. It offers a concentrated liquidity yield optimizer with self-custodial and automated market-making strategies. Users can earn optimized yields from Solana's top DeFi protocols and manage their positions in one platform. Hawksight aims to build Solana's largestdecentralized finance yield aggregator protocol.
• Hybrid — Hybrid is a fintech company that offers a decentralized central AI tool with Web3's ecosystem of AI experts, agents, and data.
• Liquorice — Equip your trading with inventory management tools and unified access to DeFi protocols like 1inch and Uniswap X. Join Liquorice's intent-based lending markets.

Portfolio highlights

• Spicenet — Spicenet is a hyper-fast Layer 2 (L2) trading solution, engineered as a custom application rollup to deliver ultra-fast, reliable, and efficient transaction processing for seamless trading experiences.
• Real Finance — Purpose-built blockchain infrastructure for issuing, managing, settling, and distributing tokenized financial assets across institutional workflows. Regulated banking integrated at the foundation.
• WorkQuest — About WorkQuest WorkQuest is a decentralized employment and workforce automation protocol enabling employers and workers to collaborate through smart contracts, stablecoin payments, AI matching engines, and on-chain reputation scoring. The platform transforms global employment into a transparent, verifiable, and borderless digital labor economy.

Portfolio highlights

• Anoma — Anoma is the distributed operating system that frees builders from blockchain complexity. Build apps that are easy, private, and compatible with any chain.
• Keplr — Introducing the first, and leading, IBC-enabled wallet for Cosmos and beyond
• Datachain — Datachain is a tech company that revolutionizes blockchain interoperability and stablecoin settlement. we aim to make it possible for the world to interact as one network, making it easier to use a variety of services.

Portfolio highlights

• Revomon — Revomon launches on mobile after a first successful version in VR gathering 200,000+ downloads. Join this new journey introducing an online RPG Open-World with 10+ regions to explore and 320+ creatures to catch
• MonoPolist — MonoPolist offers a cross-platform gaming universe with NFT features and rewards players with MONO and MOB tokens.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• Thyme Care — Thyme Care is a dedicated team of nurses and care experts offering value-based cancer care to help you through all phases of the cancer experience.
• Angle Health — Angle Health provides a technology-enabled health insurance platform to simplify employer-sponsored healthcare benefits. The company's service offers fully configurable group health plans that employers can tailor and deploy quickly through its “Benefit Builder” and “Quote-to-Card” tools, often eliminating the need for individual member-level underwriting. It integrates medical, pharmacy, demographic, claims, and population-health data with AI-enabled analytics to help employers, brokers, and care teams anticipate health needs and design plans accordingly. Angle Health’s plans typically include telemedicine, digital behavioral health, chronic-disease management, and access to a national network of doctors and providers—services that are often bundled into standard coverage.
• Spark Pediatrics — Discover Spark Pediatrics, offering comprehensive, nurturing medical daycare for children with complex medical needs. Experience our dedicated pediatric care.

Portfolio highlights

• Starbots — Starbots is Solana's first-ever battle NFT game.
• Linear — Linear allows the user to manage software development and track bugs. Built for speed and efficiency.The founders started Linear from their own frustrations building software projects in successful high-growth companies like Airbnb, Coinbase and Uber. The founders wanted to create the tools that focus us and its team in making progress, not getin the way. Tools that are fast and efficient. Speed and performance were the main things Linear focuses on early on and keep focusing on that.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• TronBank.Pro — TronBank.Pro is a DeFi platform that offers energy leasing, TRX staking, and on-chain yield optimization services via smart contracts.
• TradingRazor — TradingRazor is an AI-native trading decision and market intelligence platform engineered specifically for multi-chain cryptocurrency and decentralized finance (DeFi) markets. Rather than acting as an asset custodian or execution venue, the system serves as a predictive analytics layer that tracks fragmented on-chain capital flows, cross-marketdata, and emerging arbitrage opportunities.
• Block Security Arena — Block Security Arena is a next-generation Web3 security learning platform that leverages AI-powered quizzes, immersive hands-on Capture The Flag (CTF) challenges, and expert-led video courses to help developers, security researchers, and blockchain enthusiasts build real-world skills in identifying, understanding, and mitigating smart contract andblockchain security vulnerabilities.

Portfolio highlights

• A-World — Welcome to Animal World, a battle game based on #BNBCHAIN's super metaverse card tower defense. By setting up a hero tower to destroy monsters.
• NeuronX — NeuronX Protocol is the pioneering decentralized lending protocol on Dfinity, setting the stage for smart DeFi. By focusing on AI-driven automation and enhanced user experiences, NeuronX aims to revolutionize the DeFi landscape and appeal to a broader audience. At the core of NeuronX is a groundbreaking innovation: AI-Powered Smart LiquidityPlatforms (AILPs). These AILPs are advanced vault strategies operated by intelligent AI algorithms. Users can effortlessly gain leverage by simply depositing a base asset. Behind the scenes, AILPs leverage AI to automate complex transactions and continuously rebalance positions, ensuring optimal leverage without the risk of liquidation. This integration of AI streamlines the process, making advanced financial strategies accessible and hassle-free.
• Vue Protocol — Community-First Layer for AI Memecoins. @solana @pumpdotfun @ton_blockchain Dvo1Fb7FxtUxsLbcQaizftfUT9HtL9P6swaQAScZDeQQ

Portfolio highlights

• MSafe — MSafe offers the most secure, decentralized, scalable Web3 non-custodial, multi-signature solution built on Move, ideal for dApp developers to use for treasury management, token management, smart contract development, blockchain protocol admin control, live on Aptos
• Polysights — Polysights is the intelligence and execution layer for prediction markets: market discovery, a trading terminal, research, and insider tracking in one place.
• Turtle Club — Aggregated, diligenced, personalized onchain yield management.

Portfolio highlights

• ZAP — ZAP offers a reputation-based token distribution protocol that supports fair rewards for user contributions within the Blast ecosystem. It enables users to participate in various projects through missions and seamless investment options. Additionally, ZAP is expanding its services to other blockchains and developing tools to simplify access toventure-capital-backed projects.
• Galaxis — Galaxis maintains an engagement platform that aims to transform and strengthen the relationship between creators and their communities. The company's platform assists creators by injecting simple NFTs with unique utilities that can expand and alter.
• Velvet Capital — Velvet Capital is a DeFi operating system that helps launch and manage on-chain funds and structured products. Velvet Capital offers its users a way to gain exposure to digital assets.

Portfolio highlights

• XOCIETY — XOCIETY is a POP Shooter with RPG progression. Shoot, Earn, Pioneer: Now We Live in XOCIETY.
• The FishVerse — FishVerse combines GameFi, AI, and blockchain technology, allowing players to fish in a dynamic open environment from their own homes.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• Ankr — Get faster, more reliable multi-chain development tools
• WOO Network — Discover WOO's ecosystem of centralized and decentralized apps to seize every opportunity in crypto.
• AllianceBlock — Find the resources and tools to build scalable, interoperable solutions with Nexera's modular infrastructure.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Amyl Therapeutics — Amyl Therapeutics is a preclinical stage biotechnology company. Amyl Therapeutics uses a novel mechanism to bind to the amyloid fold of toxic protein aggregates of various types, including antibody light chain (AL) or transthyretin (TTR) aggregates, which accumulate in peripheral organs to cause systemic amyloidosis diseases, but also amyloid-β(Aβ), Tau, and α-synuclein aggregates, which accumulate in the brain to cause Alzheimer's and Parkinson's diseases.

Portfolio highlights

• Neosoul — NeoSoul uses an open architecture with autonomous agents operating under user-defined constraints to link agent intelligence, deterministic capital controls, and verifiable market execution.
• ORO — ORO is an AI-powered DeFi companion that lets users manage, trade, stake, lend, and research crypto assets through natural-language conversations, ORO aims to simplify onchain finance by bringing portfolio management and DeFi actions into one conversational interface.
• GAEA — GAEA is a decentralized artificial intelligence training network and data infrastructure platform focused on building a comprehensive multimodal emotional database.

Portfolio highlights

• Outer Ring — Outer Ring is a play-to-earn MMORPG (Massively Multiplayer Online Role-Playing Game) video game in the science fiction and fantasy universe. The game model is freemium, i.e., the player can access and play from the very first moment without paying anything and can obtain benefits by earning achievements.
• Infinity Arena — The place to connect players who love tactical card games or have passionate about collecting valuable and rare NFT cards.
• Ancient Kingdom — Ancient Kingdom is the first ancient martial arts game on the blockchain platform, pioneering the realization of real-time games on the blockchain platform.

Portfolio highlights

• CESS — CESS revolutionizes AI, DeSci, RWA, Enterprise, and more with secure, transparent, and traceable data solutions. Delivering AI computing and data infrastructure, CESS enables data privacy and sovereignty with a focus on AI Agent applications and frameworks.
• Dmail — Dmail Network is a decentralized mailbox that provides a safe and private environment for users' communication, storage, tokens, and NFTs. The company was founded by Mittal S. and Lucas L. in 2021.
• Cumulus Encrypted Storage System (CESS) — CESS revolutionizes AI, DeSci, RWA, Enterprise, and more with secure, transparent, and traceable data solutions. Delivering AI computing and data infrastructure, CESS enables data privacy and sovereignty with a focus on AI Agent applications and frameworks.

Portfolio highlights

• Demole — Demole is a play to earn NFT gamification platform.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Radom — A Decentralised Network for Coordination of Cloud Applications and Connected Assets

Portfolio highlights

• Wicrypt — Wicrypt is a dynamic organization that consistently allows its users to get paid by sharing their Wi-Fi.
• Gamic — Africa's biggest gaming guild.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• Yellow — Trades clear off-chain through state channels. Only the net result settles on-chain, across the chains participants already use.
• KIP Protocol — KIP Protocol is a decentralised AI framework unlocking digital property rights of Knowledge Assets in the AI-powered future.
• Alliance Games — Build Beyond Limits. Multiplayer for the Next, Decentralized Era.

Portfolio highlights

• Zecrey — Zecrey is a digital asset privacy protocol provider, based on the application of the Sigma protocol.
• Vee Finance — Bridge the gap between traditional banking and crypto Defi Earn fixed/flexible return on deposited assets
• The Unfettered — The Unfettered is a blockchain PC game.