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XGEN Venture, VC Fund

XGEN Venture

VC Fund

Milan, Italy

XGEN Venture is an Italian alternative investment fund manager (Società di Gestione del Risparmio, or SGR) with over 15 years of experience in the startup process and the development of innovative solutions for high unmet medical needs.

Total investments:
11
Last investment:
Lead investor:
55%
Fund size:
$186M
Last fund:

Last updated:

Industries XGEN Venture invests in

BiotechnologyHealth CareTherapeuticsMedicalLife Science

Stages XGEN Venture invests in

Series ASeries BSeedSeries C

Countries XGEN Venture invests in

ItalySwedenGermanySwitzerlandUnited Kingdom

Round sizes

Series A $11M–$98MSeries B $4.6M–$141M

Contacts

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Round size

Series A
$11M–$98M
Series B
$4.6M–$141M

Investment Focus

Industry

  • Biotechnology 8 (73%)
  • Health Care 4 (36%)
  • Therapeutics 3 (27%)
  • Medical 2 (18%)
  • Life Science 2 (18%)
See all 13 industries →

Stage

  • Series A 4 (36%)
  • Series B 4 (36%)
  • Seed 1 (9%)
  • Series C 1 (9%)

Country

  • Italy 6 (55%)
  • Sweden 1 (9%)
  • Germany 1 (9%)
  • Switzerland 1 (9%)
  • United Kingdom 1 (9%)

Team

NameTitleInvestmentsLinksEmail
Daniele Scarinci
Daniele Scarinci Co-Founder & Managing Partner
Co-Founder & Managing Partner Total investments: 1
Find email

Investments

CompanyDescriptionRoundLinks
Aptadir Therapeutics is developing RNA inhibitor-based therapeutics for treating intractable cancers and genetic conditions. $45.5M / Seed / Sep 29, 2026
Dialybrid provide product that include silkothane arteriovenous graft, SAG biomimetic nanostructure, and situ tissue engineering products. Their proprietary innovative technology, silkothane, is a hybrid material combining silk fibroin and polyurethane. Their aim is to develop a novel semi-degradable vascular access for hemodialysis. $17.2M / Series A / Sep 22, 2026
EpilepsyGTx is a late-stage biotech company exploring cutting-edge gene therapies to improve the management of focal refractory epilepsy (FRE). $33M / Series A / Dec 10, 2025
AAVantgarde Bio is developing gene therapies for inherited retinal disorders. $141M / Series B / Nov 03, 2025
Founded in 2017, Gesynta Pharma bases its R&D on research from the Karolinska Institutet. The most advanced drug candidate, GS-248, reduces inflammation and increases blood flow in the microvasculature, thereby having the potential to provide improved treatments for several serious diseases. In an ongoing clinical proof-of-concept study,GS-248 is being evaluated for its capacity to normalize vascular blood flow and reduce pain in patients with the autoimmune disease systemic sclerosis. Positive results from this study may lead to a rapid broadening of the development program towards additional indications, for example cardiovascular diseases and rheumatic diseases other than systemic sclerosis. Major shareholders include Industrifonden, Linc, Hadean Ventures, and a number of successful life science entrepreneurs. For more information, please visit www.gesynta.se $4.6M / Series B / Oct 21, 2025
NanoPhoria is a biotechnology company focused on the development of innovative cardiovascular treatments. It specializes in a non-viral, nano-in-micro delivery system for biologics, designed to target the heart directly. This preclinical stage company is exploring the potential of inhalable therapies, utilizing tissue-directed delivery methods fortherapeutic peptides and RNAs. NanoPhoria's approach aims to revolutionize the treatment of cardiovascular diseases by offering a versatile, non-viral drug delivery platform, formulated for both inhalation and other administration routes. With a dedicated team, NanoPhoria is committed to advancing cardiovascular health through groundbreaking research and development. $97.8M / Series A / Oct 06, 2025
Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases, particularly primary immunodeficiencies and inherited metabolic diseases. $52.2M / Series B / Sep 24, 2024
TES Pharma is a research-based biopharmaceutical company focusses on delivering first in class preclinical candidates that unlock the potential of novel therapeutic targets and mechanisms. $10.7M / Series A / Apr 10, 2024
ProtEmbo is designed to be a simple and reliable solution for one of the most feared complications during TAVR.The advent of transcatheter treatments for valvular heart disease has been a major revolution in the care of patients with disabilities or intercurrent illnesses that precluded undergoing stressful open cardiac surgical procedures.Nonetheless, in spite of ongoing improvements in TAVR procedures and outcomes, the occurrence of cerebrovascular events represents a significant morbidity of TAVR.Protembis was founded based on the vision to reduce the risk of cerebrovascular events, thereby improving outcomes and making TAVR even safer – especially in light of TAVR shifting to younger and lower-risk patients. The ProtEmbo System is an adjunctive device used during TAVR and removed following completion of valve implantation. The ProtEmbo is an intra-aortic filter device that is designed to deflect embolic material arising during TAVR away from the cerebral circulation. $32.5M / Series B / Mar 26, 2024
Nouscom is a developer of an immunotherapy platform that aims to create modified viral vector vaccines for cancer treatment. The company's platform makes use of a portfolio of engineered viral vectors that have been optimized for the efficient expression of long strings of tumor neoantigens. It also includes a toolkit for inducing broad andpotent antitumor T-cell responses, allowing patients to boost cancer-specific cellular immunity. $73.4M / Series C / Nov 14, 2023
See all 11 investments →

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FAQ

What does XGEN Venture invest in?

XGEN Venture invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 11 investments tracked by Shizune back companies in Italy. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does XGEN Venture invest in?

XGEN Venture typically joins rounds of $11M–$98M at Series A and $4.6M–$141M at Series B. These are whole funding-round sizes, not XGEN Venture's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds XGEN Venture took part in.

How do I contact XGEN Venture?

Public channels for XGEN Venture include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at XGEN Venture?

The team at XGEN Venture includes Daniele Scarinci (Co-Founder & Managing Partner). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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