Top 50 Biotechnology Startup Investors in Israel (August 2026)

Portfolio highlights

• IBI-Ag — We develop a wide array of selective bio-insecticides to help farmers grow more at lower cost with no harm to farm workers, consumers and the environment.
• Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
• Arcuro Medical — Arcuro develops a new repair system for meniscus tears of the knee. Arcuro’s proprietary SuperBall repair system consists of a knotless, all-suture anchor and innovative delivery system. The company was founded in 2013.

Portfolio highlights

• ArQule — ArQule, Inc. is a clinical-stage biotechnology company engaged in the research and development of cancer therapeutics. The Company employs technologies, such as its ArQule Kinase Inhibitor Platform (AKIP) to design and develop drugs. The Company's product is ARQ 197, an orally administered inhibitor of the c-Met receptor tyrosine kinase. ARQ197 is being evaluated as monotherapy and in combination therapy in a Phase II clinical development program that includes trials in Microphthalmia Transcription Factor (MiT) associated tumors, non-small cell lung cancer (NSCLC), pancreatic adenocarcinoma and hepatocellular carcinoma (HCC). The Company has licensed commercial rights to ARQ 197 for human cancer indications to Daiichi Sankyo Co., Ltd. (Daiichi Sankyo) in the United States, Europe, South America and the rest of the world, excluding Japan and certain other Asian countries, where it has licensed commercial rights to Kyowa Hakko Kirin Co., Ltd. (Kyowa Hakko Kirin).
• Otic Pharma — Otic Pharma is a clinical-stage pharmaceutical company focusing on the development and commercialization of products for disorders of the ear, nose, and throat (ENT). The company has two platform technologies, each of which has the potential to be developed for multiple ENT indications. The company is currently developing anasally-administered, combination drug product (OP-02) intended to address the underlying cause of otitis media and Eustachian tube dysfunction (OM/ETD), a condition that affects more than 700 million people around the world every year. Otitis media is one of the most common disease seen in pediatric practice and the most frequent reason children consume antibiotics or undergo surgery. The company also has a foam-based drug delivery technology platform (OP-01) that can be used to deliver drugs into the ear, nose, and sinus cavities. The company is currently developing OP-01 as an improved treatment option for acute otitis externa (“swimmers ear”). For more information on the company, please visit www.oticpharma.com
• Applied Immune Technologies — Applied Immune Technologies Ltd. engages in development of therapeutic molecules for cancer, viral, and autoimmune diseases. The company develops T-Cell Receptor-Like (TCRL) antibodies that are targeted to intracellular-derived peptides for various therapeutic and diagnostic applications. Its TCRL antibodies also have diagnostic applications inpathology; and vaccine design, validation, and monitoring, as well as in the analysis of antigen presentation in disease. The company was formerly known as BioMimic Pharma. The company was founded in 2006 and is based in Haifa, Israel.

Portfolio highlights

• Brevel — Brevel developed a disruptive cultivation technology for sustainable, low cost and high quality production of microalgae for various yet untapped markets. The technology is based on high-tech indoor, sterile and fully automated systems which are illuminated from within at high intensity. The technology enables the surprising results of more than90% cost reduction and up to 200 higher yields compared to current alternatives. Brevel is using the advantageous production capabilities to enter multiple markets where microalgae derived products are needed.
• NanoGhosts — NanoGhosts’ technology is based on its founder’s research, that the Technion's commercial unit has patented in the U.S. and Europe.
• GeoRank Studio — Get your business ranked on Google, cited by ChatGPT & Perplexity, and protected from reputation damage. Specialist SEO and GEO agency. Free consultation.

Portfolio highlights

• N.Light — N.Light is a Metaverse 3D design software that allows individuals to effortlessly turn their ideas into reality.
• Hemispheric — Hemispheric develops fundamental AI technologies aimed at deciphering brain activity for innovative applications.
• MUV Interactive — MUV Interactive designs and develops innovative technology for active human sensing, providing a natural and fluent interactive experience with any type of digital application, from displayed content, and smart home appliances to IOT (Internet of Things) devices, drones and AR/VR applications. The company’s flagship product, Bird, is anintuitive device that is worn on the index finger, which transforms any space into a 3D Interactive Environment. Bird is the first device to integrate the entire spectrum of input and control methods – including touch, remote touch, gesture control and mouse functionality. This gives users the flexibility to interact with each type of digital content in the most intuitive way, whether up close or from a distance of up to 100 feet away.

Portfolio highlights

• CardiAQ Valve Technologies — CardiAQ Valve Technologies (CVT), a privately held company, is developing innovative approaches to heart valve replacement and is initially focused on transcatheter mitral valve implantation (TMVI).
• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• Acceleron Pharma — At Merck, we're following the science to tackle some of the world's greatest health threats. Get a glimpse of how we work to improve lives.

Portfolio highlights

• Adcytherix — Adcytherix is a biopharmaceutical company focused on the development of novel antibody drug conjugates (ADC) to treat high unmet need diseases such as cancer.
• Lin Health — Online chronic pain recovery program designed to get you back to the life you want to live. One-on-one coaching. Real pain reduction results.
• Connie Health — At Connie Health, our Medicare advisors help older Americans find the right Medicare plan - all at no cost to you.

Portfolio highlights

• MDI Health — Transform Quality Metrics Clinical Outcomes & Costs all inOne Platform. Your AI Co-Pilot for Medication Management
• Antidote Health — AntidoteHealth.ai offers primary care on its telehealth app on a 24/7 basis, including prescriptions & more. Book your appointment today!
• Marquee — Marquee turns football data into decision-ready insights in seconds, unifying external and internal data and filtering it through your club's sporting DNA.

Portfolio highlights

• Newmoo — Newmoo makes plant-based cheeses and dairy alternatives.
• WeedOut — WeedOut: Exploiting Sterility against Resistant Weeds
• Earth Force Technologies — Earth Force is a Vegetation Management System platform.

Portfolio highlights

• Lendbuzz — Lendbuzz is an AI-based auto finance platform that helps consumers with thin or no credit history obtain financing when purchasing a car. Powered by machine learning and proprietary algorithms, Lendbuzz is able to better assess the creditworthiness of consumers with limited credit history, who are underserved by the traditional banks. By partneringwith auto dealerships, Lendbuzz is able to offer consumers attractive financing solutions and dealerships are able to close additional business opportunities and serve a more diversified client base. Lendbuzz is headquartered in Boston, Massachusetts and was founded in 2015.
• Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
• Nocion Therapeutics — Nocion Therapeutics is a developer of novel pharmaceuticals intended to treat the conditions arising from neurogenic inflammation. The company is developing "nocions" which are a new kind of therapy that selectively affects actively firing nociceptors, enabling patients to provide targeted, robust and sustained relief for the treatment ofserious conditions including cough, itch, pain and inflammation.

Portfolio highlights

• Check-Cap — Check-Cap Ltd. is merging with MBody AI to create a leading publicly traded embodied AI company powering autonomous workforces.
• Ocon Healthcare — OCON Healthcare innovates, develops, manufactures, and commercializes cutting-edge women’s health products based on our patented IUB™ (Intra Uterine Ball) proprietary platform. The IUB™, made from a super-elastic alloy Nitinol, is an ideal carrier for multiple drugs to the uterus to treat a variety of conditions.In addition to our flagshipproduct, the IUB™ Ballerine®, OCON healthcare is developing an innovative pipeline of products utilizing the IUB™ frame for indications such as abnormal uterine bleeding (AUB), heavy menstrual bleeding (HMS), myomas/fibroids, and infertility.
• Raziel Health — Raziel Health’s mission is to bring world-class, disruptively less expensive healthcare to everyone, in the comfort of their home. Its unique, integrated system combines easy-to-use technologies that support positive patient experience, enable timely clinical intervention, and meet individual patient goals while using data analytics to supportwellness and disease management.

Portfolio highlights

• ProtAb — ProtAb develops therapeutic agents that modulate cytokine regulation, tipping the balance toward anti-inflammatory signaling pathways in the treatment of autoimmune and inflammatory diseases. Its first product, Prozumab, is a monoclonal antibody with a novel mechanism of action. It is currently in late-stage preclinical development for thetreatment of inflammatory bowel disease or IBD, ulcerative colitis or UC, and rheumatoid arthritis or RA. It operates as a subsidiary of Hadasit Bio-Holdings. HBL is a publicly traded subsidiary of Hadasit, the technology transfer company of the Hadassah University Hospital in Jerusalem in Israel.
• KAHR medical — KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders.
• Enlivex Therapeutics — Enlivex is a clinical-stage macrophage reprogramming immunotherapy company that targets diseased macrophages in patients with sepsis. The company develops an autologous and allogeneic drug pipeline for the treatment of autoimmune and inflammatory conditions such as Graft versus Host Disease (GvHD), solid organ transplant rejection, Crohn'sDisease, and other autoimmune and inflammatory disorders.The company's revolutionary approach is to induce immune tolerance by injecting apoptotic cells and facilitating their interaction with dendritic cells activates the body's innate, physiologic mechanism for down-regulating inflammation and autoimmunity.Enlivex is an Israeli-based cell immunotherapy company established in October 2005 by Professor Dror Mevorach, a world-renowned expert on clearance of dying (apoptotic) cells.

Portfolio highlights

• Atomo Coffee — Atomo Coffee is a developer of molecular coffee. Atomo has reverse-engineered the coffee bean to create a smooth cup of coffee, made of naturally derived ingredients, and more sustainable than current commercial coffee.
• SWARM — SWARM is a Software-as-a-Service platform that uses a next generation cognitive computing system, structured around a multi-agent approach which can utilize a cur
• Kuehnle Agrosystems — Kuehnle AgroSystems curates a unique set of algae originating from pristine waters and ecosystems of Hawaii, as well as tropical botanical accessions representing plants prized by Polynesian voyagers.

Portfolio highlights

• TytoCare — TytoCare offers the Home Smart Clinic - for accessible, high-quality primary care from home, with no compromises.
• Sight Diagnostics — Combining AI and breakthrough hardware to bring lab-quality CBC results to the doctor's office.
• Cadent Therapeutics — Cadent Therapeutics is a precision neuroscience company developing novel medicines that tune and modulate brain rhythms to restore cognitive and motor function in patients with serious neurological disease. The company leverages its precision neuroscience approach combining target specificity, patient selection, drug design and optimization, andnovel quantitative endpoints to create first-in-class molecules to treat movement and cognitive disorders.It was founded in 2010 and headquartered in Cambridge, Massachusetts.

Portfolio highlights

• IBI-Ag — We develop a wide array of selective bio-insecticides to help farmers grow more at lower cost with no harm to farm workers, consumers and the environment.
• Synchrony Medical — Synchrony Medical is a clinical stage medical device company developing LibAirty, a next generation, home-use, airway clearance system designed to help patients with chronic lung disease such as COPD and CF maintain clear lungs with a short, daily, proficient treatment.
• Arcuro Medical — Arcuro develops a new repair system for meniscus tears of the knee. Arcuro’s proprietary SuperBall repair system consists of a knotless, all-suture anchor and innovative delivery system. The company was founded in 2013.

Portfolio highlights

• Nopalera — Vegan, cruelty free, and Latina owned. Handmade cactus products that celebrate culture and resilience.
• Pigmentum — Pigmentum is an ag-tech firm developing a molecular technology platform that enables external gene activation in plants.
• ProFuse Technology — ProFuse Technology revolutionizes cultured meat production by shortening it duration, improving the meat quality and increasing yields.

Portfolio highlights

• PoLoPo — PoLoPo is a biotech company that produces proteins on a large scale and according to specifications. PoLoPo develops a "superAA" plant by employing directed metabolic engineering techniques and fully utilizing plants' capacity as various metabolite and green protein factories. A significant amount of free amino acids can be producedby the superAA. The increased production of amino acids is then translated into an increase in the scale at which proteins are produced in plant organs.
• SuperMeat — SuperMeat is an Israeli bio-tech and food-tech company, developing a technology to create clean meat from chicken cells in a safe and controlled environment, external to the animal’s body. SuperMeat is set to revolutionize the meat industry from its core, aspiring to secure a better future for humans and animals alike. Clean meat is grown in acontrolled, sterile environment without the use of antibiotics and without any possibility of fecal contamination, such as salmonella. Clean meat will require significantly less resources for its production (99% less land, 90% less water), making it both a healthy and sustainable food source for the coming century.
• Meala Foodtech — Revolutionary texturized plant proteins that replace eggs and hydrocolloids. Clean-label, allergen-free solutions for baking, savory foods, and dressings.

Portfolio highlights

• Nas Daily —
• ActiveLens — Full automation. Full visibility. Always in control.
• Recapp — Recapp Sports Highlights is a video-format app for NBA, NFL, CBB, WNBA, MLB, NHL, CFB, and MLS game recaps, news, and highlights in one app

Portfolio highlights

• Pigmentum — Pigmentum is an ag-tech firm developing a molecular technology platform that enables external gene activation in plants.
• Ever After Foods — We produce slaughter-free meats that prevent animal cruelty, and support health, security and sustainability for our planet and its people.
• ProFuse Technology — ProFuse Technology revolutionizes cultured meat production by shortening it duration, improving the meat quality and increasing yields.

Portfolio highlights

• KAHR medical — KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders.
• March Biosciences — Transforming Patient Care by Unlocking New Target Spaces march.biosciences is a clinical-stage company in the cell therapy field focused on developing CAR-T cell strategies to address the most challenging hematological cancers Pipeline MB-105 https://march.bio/wp-content/uploads/2023/05/shutterstock_1008023995-HD-30.mp4 Focused on Excellence Target Space Our approach combines biological and engineering insights to enable target-unlock without the risk and complexity of
• Starget Pharma — Starget Pharma develops a new generation of targeted radiopharmaceutical technologies for the treatment of solid tumors. Starget Pharma has a pipeline of novel targeted radiopharmaceutical molecules that act as a vector for selectively transferring radioisotopes to cancer tumor tissues.

Portfolio highlights

• Kimba — Kimba is the first sleep system that reads your body and responds to it silently and automatically every night, using the only sensory pathway that can reach a sleeping brain. Reserve your Kimba today!
• CopilotKit — The Enterprise-Ready Frontend Stack for Agents. CopilotKit lets you integrate LLMs or agents with real-time context, UI control, and full flexibility.
• Shifters AI — Shifters builds autonomous robotic teams for dangerous ground missions.

Portfolio highlights

• Moon Surgical — Create the OR of the future, one that is sustainable, efficient, and digitalized.
• Manus Neurodynamica — Manus Neurodynamica is a triage device to support early diagnostics in Parkinson's disease.
• Glyphic Biotechnologies — We sequence proteins. Glyphic Biotechnologies is decoding the human proteome through full coverage, de novo protein sequencing at single molecule resolution to enable the development of novel therapeutics and diagnostics and, ultimately, a deeper understanding of life itself.

Portfolio highlights

• Navina — Navina uses medically-informed AI to replace disorganized patient data with an intuitive Patient Portrait - a logical grid that makes it possible for every primary care physician to assess even the most complex cases in minutes. Designed for and loved by physicians, Navina allows for high quality and empathic patient care, resulting in better treatment, reduced missed diagnoses and enhanced financial performance for providers and payers.
• Vessi Medical — Vessi Medical is developing an innovative, IP protected cryo spray for hollow & humid organs, a new approach in the treatment of Non Muscle Invasive Bladder Cancer (NMIBC).
• Magenta Medical — Founded in October, 2012, Magenta Medical Ltd. is a privately held company that is engaged in the development of novel device solutions for the treatment of acute and chronic heart failure.

Portfolio highlights

• Integra Therapeutics — Integra Therapeutics is a developer of next generation of gene editing tools to cure diseases.
• Accipiter Biosciences — Accipiter Biosciences is a biotechnology company.
• Harness Therapeutics — Transine Therapeutics is a private biotechnology company focused on the development of a novel class of therapeutic RNAs that can upregulate protein expression with an unprecedented level of control and specificity: the SINEUPs®. The company's pioneering technology is expected to offer an entirely unique mechanism of action for currentlyhard-to-treat diseases by massively extending the druggable proteome and allowing it to address diseases that have been beyond the reach of small molecules, conventional biologics, or gene therapies.

Portfolio highlights

• LimitlessCNC — Limitless CNC is an AI-powered technology intended to improve CNC machining operations. It offers an AI CAM agent that works with NX-CAM to give industry-specific strategies and operations.
• Scala Biodesign — At Scala Biodesign, we provide our partners a unique one-shot computational protein design solutions to dramatically increase the value and accelerate the development of proteins into commercial products.
• FormX — California's trusted sustainable builders. FormX delivers fully customized single-family homes, ADUs, and backyard offices built faster with component-based modular construction.

Portfolio highlights

• Adro — Designed to work when you arrive Spend and save like a local. Easy to use. No unfair fees.
• BQP — At BQP, we’re developing a quantum-accelerated digital twin platform for mission-critical applications. The platform, BQPhy, is a back-end engine that integrates seamlessly into existing engineering workflows and operates on today’s infrastructure without requiring quantum hardware. BQPhy helps teams solve large-scale, complex challenges inengineering optimization, data-driven modeling (ML), and physics-based (CFD) simulations. We are bridging the gap between current high-performance computers and future quantum systems with probabilistic algorithms from quantum information science, unlocking simulation capabilities that were previously impractical or impossible. BQPhy reduces time, accuracy, and throughput inefficiencies, thereby accelerating development cycles, unlocking previously unexplored design spaces, lowering costs, and enhancing product outcomes.
• CryoBio — CryoBio offers a food-safe spray solution to protect crops from extreme frost, reducing losses and replacing manual labor with effective, biodegradable frost protection technology.

Portfolio highlights

• Treetoscope — The first and only commercial device that senses the internal water flow of a plant and directly measures its water consumption and real-time irrigation needs. without extrapolations based on indirect sensing technologies.Treetoscope offers a SaaS irrigation management platform, based on direct plant sensing technology. We tackle one of the mostcrucial challenges farmers face today: water scarcity and irrigation optimization. Our groundbreaking ag-tech enables the unprecedented measurement of real-time actual water use of trees (based on our patented single probe Sap Flow sensor). Through the Treetoscope solution, growers gain great value as a result of the affordability, scalability, and ease of deployment of our technology.
• MSICS Pharma — MSICS Pharma is a pharmaceutical company that manufactures and produce naturally-sourced Psilocybin for medical purpose.
• Quris — Quris Technologies is a bio-AI clinical-prediction platform is being developed to assure the safety and efficacy of medications.The company provides a fully automated, self-training AI platform accurately predicts clinical safety and efficacy for novel drugs faster and more cost-effectively while minimizing animal testing, allowing pharmacompanies to avoid the enormous risks and costs of failed clinical trials and end the reliance on ineffective animal testing.Quris Technologies was established in 2019 by Isaac Bentwich in Tel Aviv, Israel.

Portfolio highlights

• Skip Therapeutics — Skip Therapeutics develops precision, RNA-based, treatments for rare genetic diseases. Millions of people worldwide are affected by thousands of rare genetic disorders, yet the limited patient populations, further divided by patient-specific mutations, have hampered the discovery of effective treatments. Recent developments in RNA-therapeuticsprovide an enlarged molecular toolkit that can be used quickly and affordably to repair damaged genes' ability to make proteins. Computational techniques could be used to help identify sub-patient populations that would be eligible for treatment with RNA-based therapeutics and match molecular therapy options across the large landscape of known disease-causing mutations.
• Protekt Therapeutics — ProteKt Therapeutics is a drug development company aiming to develop potent and selective oral inhibitors of the kinase PKR for the treatment of neurodegenerative and neuroinflammatory diseases. The company has raised a $4M pre-A round and graduated from the FutuRx accelerator in 2019.
• Bsense Bio Therapeutics — Bsense Bio Therapeutics develops small molecules for the treatment of sensory hyperexcitability related disorders. Bsense pioneers a novel approach targeting multiple hyperexcitability-related mechanisms using a single compound, to achieve greater efficacy and safety.

Portfolio highlights

• TripleW Group NV — Making Waste History. TripleW upcycles food waste into high-value bioplastic
• ansā — Ansā is a coffee roasting solution designed specifically for the workplace. It offers a system that enables organizations to roast coffee on-site. The solution focuses on providing fresh coffee tailored to workplace preferences. The industries served include food service and hospitality.
• Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability

Portfolio highlights

• BacoCure — BacoCure is developing a novel bacterial product for local therapy of non-muscle invasive bladder cancer (NMIBC) patients.
• Splisense — Transformative RNA Based Treatments -Antisense Oligonucleotides- Targeting the Root Cause of Pulmonary Diseases Our innovative RNA based therapies, based on Antisense Oligonucleotides (ASOs), restore and modify protein functionality, addressing untreatable pulmonary diseases.
• Rebiotic Rx — Develops nanotechnology-based antibiotics with the focus on resistant bacteria

Portfolio highlights

• Enzymit — Enzymit's platform technology can build molecular machines that enable never before seen chemistry aiming to solve humanity's greatest challenges
• Lidwave — Lidwave’s deep-tech solution revolutionizes 3D sensing and the verticals relying on it by examining the biggest challenge in LiDAR technology from a new perspective, free of bandwidth limitations.
• DeepCure — DeepCure is a Boston-based therapeutics company that harnesses advanced AI, physics-based tools and automation to discover novel small molecules for challenging targets. DeepCure currently has a lead asset in IND-enabling studies and other programs focused on drugging intractable targets that have t

Portfolio highlights

• TULU — TULU is a smart platform and amenity services provider to over 10,000 people in 50 buildings across the United States, Europe and Israel. Founded in 2019, TULU provides urban tenants with on-demand access to hundreds of brand name appliances, grocery staples, micro-mobility and entertainment devices, and more. TULU’s IoT-based modular units arecustomized to provide the most necessary and useful items, while leveraging advanced machine learning tools to analyze behavioral patterns, optimize usage, refine inventory, and create a personalized experience for our users. The outcome is a new way of living, encouraging more responsible consumption, reducing the cost of living in the city, and consistent with the trend to smaller and smaller living spaces.
• Yuki — Reduce warehouse waste, prevent budget spikes, and keep queries fast across Snowflake and BigQuery. Yuki keeps AI workloads under control with budgets and priorities built in, optimizing in real time with zero engineer effort.
• Majestic Labs ai — Majestic Labs ai builds power-efficient AI servers for the largest and most advanced AI workloads.

Portfolio highlights

• Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
• Musketeer — Help anywhere, anytime. Musketeer enables personal safety, alerting people close by and emergency services that someone needs help. In addition, it builds real life communities and promotes proactive safety by allowing people to ask for assistance, such as having someone walk them to their car because it's night and they don't want to bealone. All for free.Musketeer is the first social network dedicated to personal safety. By leveraging 21st century technology (crowdsourcing, cloud, and mobile) Musketeer enables users to seek assistance from people around them in case of distress. The system also provides safety related information in real-time and in aggregate for smarter Region/City management.

Portfolio highlights

• Athian — Funding livestock sustainability via a connected carbon marketplace.
• Octarine Bio — Octarine Bio is a world leading synthetic biology platform with a core mission to drive bio-based, sustainable solutions to address the most pressing planetary issues through innovation & exploration. Inspired by nature, to protect nature.
• Meala Foodtech — Revolutionary texturized plant proteins that replace eggs and hydrocolloids. Clean-label, allergen-free solutions for baking, savory foods, and dressings.

Portfolio highlights

• Aposense — Aposense (formerly NST) is a clinical-stage molecular imaging and drug development company, with a pipeline of products based on its patented platform technology for targeting apoptosis (programmed cell death) in vivo. The company translating the science of Apoptosis (programmed cell death) into personalized patient care in multiple diseasecategories, including oncology, cardiology, and neurology. Targeting of this important biological process in-vivo opens opportunities for real-time clinical imaging of disease activity and targeted therapy.Aposense specializing in the development of novel drugs and utilizing membrane electrical forces for trans-membrane of macromolecule drugs, mainly siRNA. It also developed rationally-designed molecular nano-motors (MNMs), being novel small-molecule chemical entities and its translation into kinetic energy for movement within the hydrophobic membrane core.Aposense was founded in 1996 and is headquartered in Petah Tiqva, HaMerkaz, Israel.
• MAKO Surgical — MAKO Surgical is a medical device company, markets its advanced robotic arm solution, joint specific applications for the knee and hip, and orthopedic implants for orthopedic procedures in the United States and internationally. The company offers MAKOplasty, a restorative surgical solution that enables orthopedic surgeons to treat patient specificosteoarthritic disease. It also provides robotic arm interactive orthopedic system (RIO) consisting of a tactile robotic arm utilizing an integrated bone cutting instrument; and a patient specific visualization component, which offers pre-operative and intra-operative guidance to the orthopedic surgeon, enabling tissue sparing bone removal, and accurate implant insertion and alignment.In 2011, The company was named the No.1 on the Technology Fast 500 as the fastest growing technology company by Deloitte and received the CSSEC Award for loyal, customer-focused staff members presented by the Technology Services Industry Association and ACE Award (Achievement in Customer Excellence) from MarketTools and Fast Tech Award as one of the 25 fastest growing technology companies in South Florida by South Florida Business Journal.MAKO Surgical was founded in 2004 and is headquartered in Florida, USA.
• MobileAccess Networks — Corning Everon Network Solutions offer in-building cellular solutions to meet a broad array of design scenarios and mitigate RF propagation challenges.

Portfolio highlights

• twig bio — twig bio operates as a bioengineering startup. twig bio using AI and robotics to find sustainable replacements for harmful ingredients.
• Cosaic — Cultivated - Creamy, dairy-free indulgence
• UNCAGED Innovations — What if we could make leather without the animal? We are a biomaterials company combining the power of nature and technology to reimagine leather.

Portfolio highlights

• LaraPharm — LaraPharm Ltd. is a group of people joined together by the belief that active components found in the Cannabis plant can provide a real answer to hundreds of types of disease currently not addressed at all, or poorly addressed.
• AutoMax Motors — AutoMax Motors is a vehicle importer company. It involved in the parallel importation and selling of various private automobile products.
• MitoCareX Bio — MitoCareX Bio is a biotechnology company that focuses on the discovery and development of drugs for cancers & other life-threatening diseases.

Portfolio highlights

• Remilk — Remilk is a food-tech company that uses microbes to produce the key ingredients in milk. The company is developing technology for creating a milk substitute that is similar to cow milk in flavor, nutritional composition, composition, and functionality. It was founded in 2019 and is based in Tel Aviv, Israel.
• Pigmentum — Pigmentum is an ag-tech firm developing a molecular technology platform that enables external gene activation in plants.
• ProFuse Technology — ProFuse Technology revolutionizes cultured meat production by shortening it duration, improving the meat quality and increasing yields.

Portfolio highlights

• Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
• UltraClear — UltraClear is a skincare clinic that provides facial rejuvenation solutions for the treatment of all skin types.
• GT Medical Technologies — GT Medical Technologies, Inc. (GT), an Arizona-based medical device company, is focused on improving the lives of patients with brain tumors. GT has developed an innovative approach to treatment by combining a conformable collagen matrix with brachytherapy (radiation) seeds. The company's first product, GammaTile™ is protected by 10 US and 2Canadian issued patents, and 1 EPO patent. The product has the promise to revolutionize treatment for 176,000 patients/year in the US alone. To date, we have treated 120 patients with recurrent brain tumors in a clinical trial at Barrow Neurological Institute (BNI) and observed significant clinical improvement.

Portfolio highlights

• Brevel — Brevel developed a disruptive cultivation technology for sustainable, low cost and high quality production of microalgae for various yet untapped markets. The technology is based on high-tech indoor, sterile and fully automated systems which are illuminated from within at high intensity. The technology enables the surprising results of more than90% cost reduction and up to 200 higher yields compared to current alternatives. Brevel is using the advantageous production capabilities to enter multiple markets where microalgae derived products are needed.
• Clarifruit — First automated fruit and vegetable fresh produce quality control software solution by Clarifresh. Optimize your fresh produce QC >>
• Edete Precision Technologies for Agriculture — edete Precision Agriculture Technologies is solving the world’s ever-growing pollination challenge by developing and manufacturing an efficient, automated fruit orchard pollination system and providing optimized pollination services to companies and growers.By reducing the dependency on haphazard, insect-based pollination processes, edete’scontrolled and manageable mechanical pollination system improves the quantity and quality of fruit orchard yields.

Portfolio highlights

• Convizit — Convizit's AI automatically captures user actions, adds properties, and delivers this behavioral data directly into your analytics and marketing platforms.
• Connie Health — At Connie Health, our Medicare advisors help older Americans find the right Medicare plan - all at no cost to you.
• QuantHealth — QuantHealth is an AI company that provides a platform to simulate clinical trials in order to accelerate and de-risk drug development.

Portfolio highlights

• Shiru — Discover Shiru. We are an Ingredient Company that Identifies and Creates Functional Ingredients for the Plant-Based Industry.
• Xias Bio — Xias Bio is a biotechnology startup specializing in the production of recombinant proteins, offering formulators advanced soluble, active ingredients with improved attributes such as enhanced gel and film formation, as well as antioxidant properties. The company creates non-immunogenic natural motifs to produce a better delivery platform offunctionalities for research, beauty, and healthcare.
• Asterix Foods — Asterix Foods is a biotechnology company designed to build protein production using plant-cell culture techniques. The company's platform is developing and growing bioactive proteins for food that are scalable, functional, and complex, enabling users with plant cell-cultured and animal-free proteins.It was founded in 2022 and is located inTel Aviv, Israel.

Portfolio highlights

• Pi Therapeutics — Pi Therapeutics is a discovery-stage biopharmaceutical company aiming to develop a novel cancer drug. The company is financed by a syndicate of Takeda Pharmaceutical Company through its venture group Takeda Ventures Inc., Johnson & Johnson Innovation – JJDC, OrbiMed Israel Partners, Pontifax, and the Israel Innovation Authority, and hasoperated since March 2015 in the FutuRx biotech accelerator in Ness Ziona, Israel. The company’s mission is to develop novel first-in-class drugs directed against the ubiquitin-proteasome system (UPS), mainly for treatment of cancer.
• Skip Therapeutics — Skip Therapeutics develops precision, RNA-based, treatments for rare genetic diseases. Millions of people worldwide are affected by thousands of rare genetic disorders, yet the limited patient populations, further divided by patient-specific mutations, have hampered the discovery of effective treatments. Recent developments in RNA-therapeuticsprovide an enlarged molecular toolkit that can be used quickly and affordably to repair damaged genes' ability to make proteins. Computational techniques could be used to help identify sub-patient populations that would be eligible for treatment with RNA-based therapeutics and match molecular therapy options across the large landscape of known disease-causing mutations.
• Protekt Therapeutics — ProteKt Therapeutics is a drug development company aiming to develop potent and selective oral inhibitors of the kinase PKR for the treatment of neurodegenerative and neuroinflammatory diseases. The company has raised a $4M pre-A round and graduated from the FutuRx accelerator in 2019.

Portfolio highlights

• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• AUDIOGEN — Generate your sounds with AI. Create an infinite world of sounds - sound effects, samples, and music, instantly. Get Started Free.
• Alomana — Autonomous systems for enterprise

Portfolio highlights

• Myota — Precision prebiotic products developed by gut microbiome scientists. Clinically proven to improve your mental and physical health, and patented.
• Ilant Health — We offer a comprehensive solution that take the stress and stigma out of obesity treatment. We increase access, improve quality, and drive reduction in total cost of care.
• KÄÄPÄ Biotech — Medicinal mushrooms, biotechnology, mycology, forestry, agroforestry, and food production.

Portfolio highlights

• Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
• Vessi Medical — Vessi Medical is developing an innovative, IP protected cryo spray for hollow & humid organs, a new approach in the treatment of Non Muscle Invasive Bladder Cancer (NMIBC).
• SetBone Medical — SetBone Medical develops a new bone cement for the treatment of VCF and primarily caused by osteoporosis.

Portfolio highlights

• Bulbi — Bulbi is a child development platform designed to help parents discover online and face-to-face educational activities for their children.
• Convex — All gas, no breakages. Convex is the reactive backend platform that keeps up with you and your agents.
• Extend Robotics — Extend Human Capabilities Beyond Physical Presence

Portfolio highlights

• Gadfin — Gadfin design and develops long-range Urgent-delivery systems of the future, which is no less than a game-changer for the Medical and Time-critical deliveries market. Its system brings together traditional flight knowledge, unmanned and autonomy technology, thus redefining delivery capabilities in terms of flight radius, safety, reliability, andautomation, that is going to disrupt the world.
• Stargo — AI powered routing, pricing and payment solutions for the freight industry
• Electriq Global — Electriq is a hydrogen carrier that acts like coffee powder for a coffee machine - simplifying storage, transport, and use of hydrogen in off-grid applications and long-term storage.

Portfolio highlights

• Ukko — Our mission is to improve the lives of the millions that suffer from food allergies and gluten-related disorders
• Vensica Medical — Currently, after surgical removal of tumors found in the bladder, a drug is instilled into the bladder via a catheter. This treatment method is inefficient and ineffective: Urinary bladder cancer has the highest recurrence rates among all types of cancer (70%).Using Vensica’s device, the drug will be instilled in a quick, pain-free proceduresubsequent to the delivery of ultrasound to the urinary bladder. Ultrasound improves the uptake of the drug and its penetration into the bladder wall and is expected to improve the treatment and reduce recurrence rates.
• Nectin Therapeutics — NectinTX develops next-generation delivery platforms for immuno-oncology and precision therapeutics. Discover breakthrough protein expression technologies that power safer, more effective treatments.

Portfolio highlights

• LapSpace — LapSpace Medical was founded in 2011. It operates within the framework of the Misgav Venture Accelerator, part of The Trendines Group. The LapSpace team combines strong business and medical experience and knowledge.
• Sqwik - powered by Geev.Me.Tech LTD — Sqwik is a new way to create, join & follow fun activities, with new friends, within 3 hours.
• Digma Medical — Digma Medical | DiaGone - safe, one-time, 30 minute, minimaly-invasive, GI procedure for Restoring Glycemic Control for T2DM & NASH patients | No Implant

Portfolio highlights

• Hooked Foods — Hooked Foods is working on a plant-based tuna substitute. By serving delicious plant-based seafood for everyone to enjoy, the company is leading the transition to a healthier seafood ecosystem. The company was established in 2019 and is headquartered in Sweden.
• Perfat Technologies — Perfect fats for better foods.
• Roslin Technologies — Roslin Tech is on a mission to improve protein production through disruptive technologies. Our core capability is in animal stem cells; we have developed the world’s perpetually self-renewing, pluripotent stem cells for animals (iPS cells) which will accelerate the development of cultivated meat for the consumer market.