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Pontifax, VC Fund

Pontifax

VC Fund

Herzliya, Israel

Pontifax is a healthcare-dedicated venture capital firm.The fund focuses on innovative bio-pharma opportunities.

Total investments:
117
Last investment:
Lead investor:
24%
Fund size:
$14M
Last fund:

Last updated:

Industries Pontifax invests in

BiotechnologyHealth CarePharmaceuticalTherapeuticsMedical

Stages Pontifax invests in

Series ASeries BSeries CFunding RoundPost-IPO Equity

Countries Pontifax invests in

United StatesIsraelFranceThe NetherlandsBelgium

Round sizes

Series A $6.3M–$110MSeries B $20M–$130MSeries C $12M–$101M

Contacts

NameEmailPhoneSocials

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Round size

Series A
$6.3M–$110M
Series B
$20M–$130M
Series C
$12M–$101M

Investment Focus

Industry

  • Biotechnology 57 (49%)
  • Health Care 46 (39%)
  • Pharmaceutical 22 (19%)
  • Therapeutics 21 (18%)
  • Medical 20 (17%)
See all 30 industries →

Stage

  • Series A 29 (25%)
  • Series B 24 (21%)
  • Series C 18 (15%)
  • Funding Round 11 (9%)
  • Post-IPO Equity 6 (5%)
See all 10 stages →

Country

  • United States 31 (26%)
  • Israel 24 (21%)
  • France 7 (6%)
  • The Netherlands 3 (3%)
  • Belgium 2 (2%)
See all 10 countries →

Team

NameTitleInvestmentsLinksEmail
Ohad Hammer
Ohad Hammer Partner
Partner Total investments: 19
Find email
Ran Nussbaum
Ran Nussbaum Managing Partner and Co-Founder
Managing Partner and Co-Founder Total investments: 10
Find email
Tomer Kariv
Tomer Kariv Co-Founder and Chief Executive Officer
Co-Founder and Chief Executive Officer Total investments: 7
Find email
Momi Karako Partner
Partner Total investments: 1
Find email

Investments

CompanyDescriptionRoundLinks
Crystalys Therapeutics Crystalys Therapeutics
Crystalys Therapeutics is a clinical-stage biopharmaceutical company transforming the treatment of gout. $130M / Series B / Jul 22, 2026
ADCendo ADCendo
ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment. $75M / Series C / Apr 14, 2026
Adcytherix Adcytherix
Adcytherix is a biopharmaceutical firm that specializes in the development of new antibody drug conjugates (ADC) to treat diseases with a high unmet need, including cancer. $122.8M / Series A / Oct 16, 2025
Adcytherix Adcytherix
Adcytherix is a biopharmaceutical firm that specializes in the development of new antibody drug conjugates (ADC) to treat diseases with a high unmet need, including cancer. $122.8M / Series A / Oct 16, 2025
Step Pharma Step Pharma
Step Pharma is a spin-off of Imagine Institute stemming from Pr. Alain Fischer’s research on genetic immunodeficiencies. Step Pharma is a joint venture between Imagine, a research and innovative healthcare institute, Sygnature Discovery, a leading provider of integrated drug discovery resource and expertise, and Kurma Partners, a major player inthe funding of healthcare and biotechnology in Europe. $44.3M / Series C / Oct 15, 2025
Crystalys Therapeutics Crystalys Therapeutics
Crystalys Therapeutics is a clinical-stage biopharmaceutical company transforming the treatment of gout. $205M / Series A / Sep 30, 2025
Kamari Pharma Kamari Pharma
Kamari Pharma develops innovative treatments for unmet needs and rare diseases in dermatology. $23M / Series A / Jun 03, 2025
Kamari Pharma Kamari Pharma
Kamari Pharma develops innovative treatments for unmet needs and rare diseases in dermatology. $23M / Series A / Jun 03, 2025
Abcuro Abcuro
Abcuro’s mission is to develop a new class of immune-modulatory bio-therapeutics for treating both autoimmunity and cancer. They leverage the systematic target validation and clinical insights gained by its founders to identify new targets. Their intensive use of bioinformatics to interrogate the transcriptome of human disease together with ex-vivovalidation in diseased tissue has uncovered new approaches to target key compartments of the immune system.The company was incorporated in 2015 and is based in Newton, Massachusetts. $200M / Series C / Feb 12, 2025
Lutris Pharma Lutris Pharma
Lutris Pharma develops drugs to improve anti-cancer therapy effectiveness. The company develops the topical B-Raf inhibitor LUT014, a proprietary small molecule that allows administration of epidermal growth factor receptor (EGFR) inhibitors to patients without the interruptions caused by typical cutaneous side effects.Lutris Pharma wasestablished in 2015 and is based in Tel Aviv-yafo, Israel. $30M / Venture - Series Unknown / Jan 28, 2025
See all 117 investments →

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FAQ

What does Pontifax invest in?

Pontifax invests primarily in Biotechnology, Health Care and Pharmaceutical startups, most often at Series A and Series B stage. Most of the 117 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Pontifax's check size?

Pontifax typically joins rounds of $6.3M–$110M at Series A, $20M–$130M at Series B and $12M–$101M at Series C. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Pontifax participates in.

How do I contact Pontifax?

Public channels for Pontifax include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Pontifax?

The team at Pontifax includes Ohad Hammer (Partner), Ran Nussbaum (Managing Partner and Co-Founder) and Tomer Kariv (Co-Founder and Chief Executive Officer). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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