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HBL Hadasit Bio Holdings, VC Fund

HBL Hadasit Bio Holdings

VC Fund

Jerusalem, Israel

HBL Hadasit Bio Holdings is a VC fund in Jerusalem focused on Biotechnology and Medical. Hadasit Bio-Holdings Ltd. ("HBL") was founded and floated on the Tel Aviv Stock Exchange (TASE : HDST ) and recently on the OTC (OTCBB : HADSY ) in order to allow public participation in the highly promising field of biotechnology.It serves as a precedent in biotech financing - for the first time, public investment is allowed toparticipate in a holding entity including companies based on IP generated by Israel’s foremost medical research center – Hadassah University Hospital ("HU").In addition to the public holdings (54%) – including major Israeli institutional investors, HBL is held by Hadasit (www.hadasit.co.il) (36%) and Consensus Business Group (http://www.consensusbusiness.com) (10%). The traded stock, as a unique investment vehicle, provides investment exposure to a select cluster of 6 biotech companies - all based on inventions developed and owned by HU.HBL is a publicly traded subsidiary of Hadasit Ltd. – the technology transfer company of the Hadassah University Hospital in Jerusalem, Israel. Hadasit was established for the purpose of promoting and commercializing the intellectual property (IP) and R&D capabilities generated by Hadassah, aimed at finding solutions to problems faced by modern medicine.

Total investments:
11
Last investment:
Lead investor:
9%

Last updated:

Industries HBL Hadasit Bio Holdings invests in

BiotechnologyMedicalHealth CarePharmaceuticalBiopharma

Stages HBL Hadasit Bio Holdings invests in

Funding RoundSeedSeries ASeries BVenture - Series Unknown

Countries HBL Hadasit Bio Holdings invests in

Israel

Contacts

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Investment Focus

Industry

  • Biotechnology 3 (27%)
  • Medical 2 (18%)
  • Health Care 2 (18%)
  • Pharmaceutical 2 (18%)
  • Biopharma 1 (9%)
See all 7 industries →

Stage

  • Funding Round 2 (18%)
  • Seed 1 (9%)
  • Series A 1 (9%)
  • Series B 1 (9%)
  • Venture - Series Unknown 1 (9%)

Team

NameTitleInvestmentsLinksEmail
CFO Total investments: 0 Find email
Rafi Hofstein
Rafi Hofstein President & CEO
President & CEO Total investments: 0
Find email

Investments

CompanyDescriptionRoundLinks
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $46.5M / Venture - Series Unknown / Jun 16, 2021
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $18M / Venture - Series Unknown / Feb 25, 2020
Enlivex Therapeutics Enlivex Therapeutics
Enlivex is a clinical-stage macrophage reprogramming immunotherapy company that targets diseased macrophages in patients with sepsis. The company develops an autologous and allogeneic drug pipeline for the treatment of autoimmune and inflammatory conditions such as Graft versus Host Disease (GvHD), solid organ transplant rejection, Crohn'sDisease, and other autoimmune and inflammatory disorders.The company's revolutionary approach is to induce immune tolerance by injecting apoptotic cells and facilitating their interaction with dendritic cells activates the body's innate, physiologic mechanism for down-regulating inflammation and autoimmunity.Enlivex is an Israeli-based cell immunotherapy company established in October 2005 by Professor Dror Mevorach, a world-renowned expert on clearance of dying (apoptotic) cells. $10M / Apr 23, 2018
Enlivex Therapeutics Enlivex Therapeutics
Enlivex is a clinical-stage macrophage reprogramming immunotherapy company that targets diseased macrophages in patients with sepsis. The company develops an autologous and allogeneic drug pipeline for the treatment of autoimmune and inflammatory conditions such as Graft versus Host Disease (GvHD), solid organ transplant rejection, Crohn'sDisease, and other autoimmune and inflammatory disorders.The company's revolutionary approach is to induce immune tolerance by injecting apoptotic cells and facilitating their interaction with dendritic cells activates the body's innate, physiologic mechanism for down-regulating inflammation and autoimmunity.Enlivex is an Israeli-based cell immunotherapy company established in October 2005 by Professor Dror Mevorach, a world-renowned expert on clearance of dying (apoptotic) cells. $8M / Series B / Sep 19, 2017
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $2.4M / Sep 09, 2013
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $3M / Apr 14, 2011
ProtAb ProtAb
ProtAb develops therapeutic agents that modulate cytokine regulation, tipping the balance toward anti-inflammatory signaling pathways in the treatment of autoimmune and inflammatory diseases. Its first product, Prozumab, is a monoclonal antibody with a novel mechanism of action. It is currently in late-stage preclinical development for thetreatment of inflammatory bowel disease or IBD, ulcerative colitis or UC, and rheumatoid arthritis or RA. It operates as a subsidiary of Hadasit Bio-Holdings. HBL is a publicly traded subsidiary of Hadasit, the technology transfer company of the Hadassah University Hospital in Jerusalem in Israel. $4M / Series A / Apr 23, 2010
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $1.5M / Dec 01, 2009
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. $500K / Jan 28, 2009
KAHR medical KAHR medical
KAHR Medical ("KAHR") is pioneering the development of "third generation biological drugs," a unique class of proprietary fusion-protein molecules with clear and far-reaching advantages. KAHR's technology represents a paradigm shift in protein-based pharmaceuticals that will significantly expand available treatment optionsfor cancer and autoimmune disorders. Seed
See all 11 investments →

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FAQ

What does HBL Hadasit Bio Holdings invest in?

HBL Hadasit Bio Holdings invests primarily in Biotechnology, Medical and Health Care startups, most often at Funding Round and Seed stage. Most of the 11 investments tracked by Shizune back companies in Israel. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact HBL Hadasit Bio Holdings?

Public channels for HBL Hadasit Bio Holdings include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at HBL Hadasit Bio Holdings?

The team at HBL Hadasit Bio Holdings includes Liat Hadad Simhayoff (CFO) and Rafi Hofstein (President & CEO). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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