Top 50 Wellness Startup Investors in Japan (June 2026)

Portfolio highlights

• Fondi — fondi is a completely new English conversation communication service that allows you to live a virtual communal life with the world.
• Taian — Taian, which specializes in bridal industry services and software. They also provide ''Concept Marry,'' which allows couples to design invites and seating charts that match their wedding theme, as well as display guest information on Oiwaii.
• Knowledge Work — Knowledge Work specializes in the development and sales of software for companies.

Portfolio highlights

• Eitoss — Eitoss is a technology company which has developed and provided the proposal improvement cloud "Cayzen".
• Recerqa — Recerqa is a supply chain management SaaS that utilizes advanced development technology and AI to improve the purchasing, inventory, and sales management experiences.
• Finovo — Finovo specializes in the research, development, operation, and maintenance of cutting-edge accounting and financial software solutions.

Portfolio highlights

• Find — Find is a software company that provides cloud development and operation services.
• Yosemite — Yosemite is a wellness company that provides health and wellness products, supplements, skincare, and personal care items.
• CommerceX Holdings — CommerceX Holdings is a DX infrastructure company group that uses technology to replicate retail growth, drawing on on-site knowledge gained from running its own businesses.

Portfolio highlights

• Oryzae — Oryzae attempts to alleviate social challenges through ancient Japanese fermenting processes.
• Awarefy — Awarefy is a mental health tech startup that offers CBT-based apps to maximize well-being.
• New Space Intelligence — New Space Intelligence is a space research company that provides satellite data pipeline services to optimize user requests.

Portfolio highlights

• AiCAN — AiCAN provides system planning and development, data analysis, IT, and consulting services related to child welfare.
• 3S — 3S is a SaaS developer platform that provides and operates 24-hour home nursing care services through technology.
• CI Partners — CI Partners mission is to "eliminate the word 'disability' from this country," and with the message "Everyone is a star."

Portfolio highlights

• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
• Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.

Portfolio highlights

• YOUTRUST — YOUTRUST is a startup to operate YOUTRUST a referral recruitment platform for side-job change.
• Orange — Orange is a developer of a variety of deep-learning models with a focus on computer vision and natural language processing for comics.
• Teller Novel — Teller Novel is an online platform that publishes stories based on terror novels in the form of comics.

Portfolio highlights

• Anchi — Anchi is a technology company that provides user-friendly services to support V-talents.
• Awarefy — Awarefy is a mental health tech startup that offers CBT-based apps to maximize well-being.
• Torihada — Torihada is a creative firm specializing in influencer marketing, creating content, and digital marketing.

Portfolio highlights

• REVORN — REVORN is a fragrance AI and DX research and development company. They develop products such as odor sensors that can respond to odor issues and needs. They provide consultation at a range of levels, from identifying issues to developing solutions.
• Log build — Log build offers a new form of on-site management that enables productivity improvement and real-time visualization and sharing of on-site information through on-site management robots and VR software. The company provides AI development, VR development, construction site construction management robot, cloud site management, and construction siteplatform.
• LENZO —

Portfolio highlights

• Jualo — Situs jual beli online barang baru dan bekas yang mudah dan aman untuk digunakan bagi masyarakat Indonesia. Jadikan Jualo.com teman jual belimu.
• Caduceus Foundation — Caduceus a foundation building a blockchain protocol for the metaverse. Caduceus has developed a meta-array full-merge transaction engine that draws on the matric processing methods of GPUs and AI NPUs.
• WEE marketplace — WEE is an internet-based company operating from the United Arab Emirates, focusing on providing a marketplace platform that caters to the needs of its users by offering a wide selection of goods with the convenience of fast delivery services. Established in 2021, WEE aims to enhance the shopping experience by ensuring that customers can shop onlineand receive their orders swiftly, emphasizing the value of saving time. With a team of 45 employees, WEE supports various payment methods, including Cash on Delivery, and promotes customer satisfaction with a 14-day free return policy. The company also engages in community activities, such as sponsoring events, to maintain a close relationship with its user base.

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• Epistra — Epistra accelerates research and development in life sciences.
• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.

Portfolio highlights

• iiba — Iiba is a geospatial platform that specializes in providing location information related to child-rearing.
• xxxxnese — xxxxnese is a logistics company that focuses on import, export, domestic sales, influencer marketing, and software development businesses.
• Kiwami — Kiwami offers sales promotion assistance and labor-saving solutions through the virtual store clerk.

Portfolio highlights

• Takadao — Takadao builds technology that enables communities to pool money together to mutually insure one another without the need for an insurance company.
• Meme — MEME is a money app for parents and children to make money more familiar and simplifies the flow of money.
• EduCare — EduCare provides affordable solutions to financial assistance for giving education to students.

Portfolio highlights

• Opt Fit — Opt Fit is a fitness industry that provides fitness, wellness and health-care services.
• Gaxi — Gaxie is an IT firm that provides a cloud management system and manages scholarship sites for business.
• Helical Fusion — Helical Fusion is a startup company that aims to commercialize fusion energy using magnetic confinement of high-temperature plasmas.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
• Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Portfolio highlights

• OASIZ — Oasiz is a creative agency that provides vertical video production and business consulting services.
• MTU — MTU offers medical security cloud services to medical organizations and delivers IT support, including the recent cyber harm to medical institutions, both online and offline.
• Urth — Urth is an IT company that specializes in architectural design by providing corporations with a metaverse for architects' business models.

Portfolio highlights

• Sazo — Sazo specializes in constructing a global e-commerce and logistics network with AI.
• Pragtech — Pragtech develops and operates parking lot service software that helps to eliminate payment congestion and reduce operating costs.
• Shinsekai Technologies — SHINSEKAI Technologies focuses on supporting companies, enabling them to advance their services to Web3 and NFT technologies.

Portfolio highlights

• Recho — Recho’s voice AI solutions must offer some unique features. Recho has a mission to "create the future of communication" and provides the VoiceAI platform and its application, Voice Agent.
• Pliant — Pliant makes the latest generation of corporate credit cards that adapt perfectly to business processes and needs.
• Captain Fresh — Captain Fresh is a freshwater fish and seafood supply chain platform. Captain Fresh is a B2B marketplace leveraging technology to deliver the fastest harvest-to-retail in the industry. The company focuses on aggregating the fragmented retail demand across the country and linking them to the small fishermen and farmers throughout the Indian coast.The company was founded in 2019 and is based in Bengaluru, India.

Portfolio highlights

• Vently — Discover the best nightlife events in SF.
• PvX Partners — PvX Partners is a platform designed to help consumer apps scale. PvX Capital is our first line of services focused on cohort financing: fast, flexible capital without the risk and drawbacks of traditional equity or debt. PvX Capital enables you to scale marketing spends meaningfully without the worry of equity dilution or loan defaults. PvX is alsodeveloping an operating system for growth — a unified platform enabling incremental ROAS. A single integration that will grant you access to the industry’s most useful tools proven to help consumer businesses scale.
• Habit Factory — Habit Factory provides financial big data analytics solutions.

Portfolio highlights

• Sazo — Sazo specializes in constructing a global e-commerce and logistics network with AI.
• Vitom — Vitom is a FoodTech startup that addresses the issues of sustainability and reliability in the food industry.
• CrossVision — CrossVision offers solutions and services specific to the VTuber market.

Portfolio highlights

• Agatha — Agatha is a provider of strategic software solutions to the health care and life sciences industry. It is dedicated to helping hospitals, biotechnology, pharmaceutical, contract research organizations, and medical device firms optimize the management of their quality and clinical documentation and processes.
• Aperza — Aperza's mission is to contribute to redesigning the manufacturing industry by eliminating three barriers in the industry which are the barrier of information, transaction and communication which most of companies and people often face in this industry.Manufacturing industry is Japanese core industry. We would like to contribute to therebirth of this industry by those activities such as supporting those companies who challenges the global market and supporting those start-ups who tries brand-new industry trend such as Industry 4.0, smart factory or IoT. We believe that this lead to the increase of the people in this industry, and the growth of the industry eventually.
• Bureau — Bureau is trust network that facilitates end-to-end identity verification, compliance, and fraud prevention for new-age businesses.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• Lavol —
• Morus — Morus is a university-based biotech startup developing functional food ingredients from silkworms to address global health and nutrition challenges.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• BACKSEAT — BACKSEAT provides embedded crypto exchange and Web3 Services.
• Forest — Forest Co., Ltd. operates as an e-commerce aggregator, seeks to identify sustainable, high-quality products and brands that embrace the spirit of Japan and help them grow and enter the global market by using the power of technology.
• Super Galaxy Records — Super Galaxy Records is a company that plans and produces IP that creates new works, and is also a record company that produces and manages voice actors and artists.

Portfolio highlights

• AceRNA — AceRNA contributes to regenerative medicine and drug discovery through the discovery of novel miRNA functions. It began operation in April 2018, with its headquarters in Kyoto in Japan.
• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Go Visions — Go Visions engages in the edutainment tech for children and human resources services.

Portfolio highlights

• M&A Cloud — M & A is a Match Platform for Small & Medium Venture Companies
• TrustHub — TrustHub operates an e-commerce marketplace "Clove" that specializes in trading collectibles.
• Tokyo Artisan Intelligence — Tokyo Artisan Intelligence develops od purely domestic AI high-speed code generation tools as part of deep learning and hardware research. Their objectives are to contribute to the development of new computational technology and its application in society, particularly by providing experts through the training of doctoral students.

Portfolio highlights

• Wewill — Wewill is a consulting company that provides accounting, SaaS, business development, and business consulting services.
• Grand Central — Grand Central is a consulting company specializing in the sales field.
• Seiwa Holdings — Seiwa Holdings is a company that specializes in the welding of large structures. It holds a significant share in the large sign industry in the Chubu region. The company also has a subsidiary, Toei Coating, which boasts one of the largest facilities in Gifu for electric zinc plating. Seiwa Holdings is also involved in the production of road signposts and bridge fall prevention devices. The company operates in the financial services industry and has a workforce of 2 employees.

Portfolio highlights

• KAICO — KAICO is a pharmaceuticals, diagnostic drugs production company.
• Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
• Quollio Technologies — Quollio Technologies is an IT company that specializes in corporate data governance, SaaS, metadata management, and software solutions.

Portfolio highlights

• TYPICA — TYPICA is a marketplace where you can directly trade unique and high quality green coffee beans in units of one bag.
• At Forest — At Forest is an end-of-life service provider that organizes circular burial services for the deceased.
• Rei-Frontier — Rei-Frontier Inc. is the Japanese company which provides the mobile application using augmented reality technology. Rei-Frontier Inc. is based in Tokyo, Japan and was founded in 2008.

Portfolio highlights

• MedUp — MedUp operates foro CRM, a SaaS CRM tool that provides hospitals with sales and marketing support, data analysis and visualization, and more.
• ACCEL Stars — ACCEL Stars is a fitness and wellness firm that offers sleep diagnosis and examinations like sleep health, hygiene and medical devices.

Portfolio highlights

• AIQ — AIQ is a Artificial intelligence technology development
• MIRROR FIT — MIRROR FIT provides online fitness services. MIRROR FIT features include AI-assisted high-level form checks, game-like exercises, communication with friends, and positive support. They have programmes for novices and advanced users. It includes content such as live lessons from popular trainers, personal training, and over 300 different types ofon-demand classes.
• Skyfall — Skyfall is a media business and internet advertising company. It is an online advertising platform for online marketing, internet advertising, digital advertising, and web advertising which uses the internet to promote products and services to audiences and platform users.

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• Auba — Auba is engaged in open innovation program, consulting specialized in Ol, and media outreach activities.
• Lx Design — Lx Design is an application that connects schools with people who wants to work as a teacher.

Portfolio highlights

• KAKEAI — KAKEAI, an AIcloud system that improves the status of member management in the middle management layer as its main business.
• Katagrma — KatagrMa is the first organization that optimizes the organization and human resources development.
• Recustomer — Recustomer is an IT company that develops software for digital payment and provides support for web development.

Portfolio highlights

• One Medica — One Medica is a platform that provides people outside of China with access to Japan's state-of-the-art medical care. They collaborate with numerous Japanese medical facilities to offer online second opinions and comprehensive medical services for tourists visiting Japan.

Portfolio highlights

• FELIQS — FELIQS is a preclinical-stage start-up company established based on the robust science from molecular pathobiology, department of pharmaceutical science, Kyushu university.
• ATOMica — ATOMica is a co-working space and business management company for conference rooms, event venues, circles, and schools. The company uses coworking spaces as HUBs to provide services that maximize individuals' power. It can be used for a variety of purposes, including coworking space, shared office space, meetings, events, and web seminars. Itis also possible to use it only once. They plan and run local communities that bring together a diverse range of people, including students, workers, businesses, universities, and governments.
• OPTEMO — OPTEMO develops and supplies sales technology that allows businesses and customers to connect through a website.

Portfolio highlights

• SARAH — SARAH has been working on the planning and operation of the gourmet community app "SARAH", which operates a menu gourmet site "SARAH" that allows you to search for items you want to eat from menu-based posts.
• MTU — MTU offers medical security cloud services to medical organizations and delivers IT support, including the recent cyber harm to medical institutions, both online and offline.

Portfolio highlights

• ARCH — ARCH provides research, development, operation, and support systems for gynecology and fertility treatment solutions
• Sunnies — Sunnies is a new-generation password manager that manages user privacy and account information.
• Pathfinder — Pathfinder is a research and development company that provides MaaS and delivery vehicle application development services.

Portfolio highlights

• Reiwa Travel — Reiwa Trave is a digital travel agency intended that optimizes overseas travel. The company's platform uses online travel booking tools that provide digitalized contracts along with trip management, thereby enabling its customers' vacation and leisure experiences.
• Atlast health — Atlast Health provides high-quality psychological care to patients through technology.
• Yosemite — Yosemite is a wellness company that provides health and wellness products, supplements, skincare, and personal care items.

Portfolio highlights

• PeopleX — PeopleX encourages and assists employees in their professional development.
• Digireha — Digireha is an IT company that provides a tool for rehabilitation by combining digital art and sensors.
• H2 — H2 Corporation offers an automation solution called "AI Estimation" for estimating tasks.

Portfolio highlights

• MTU — MTU offers medical security cloud services to medical organizations and delivers IT support, including the recent cyber harm to medical institutions, both online and offline.
• Recustomer — Recustomer is an IT company that develops software for digital payment and provides support for web development.
• Codeless Technology — Codeless Technology is a software development company that helps businesses save time, reduce errors, and improve overall efficiency.

Portfolio highlights

• xMap — Explore xMap, a premier location intelligence SaaS platform. Access vast data sets from multiple industries worldwide, visualize on maps, and drive data-driven decisions. Elevate your business strategy with unparalleled insights and achieve market leadership.
• Pi-xcels — Eco-friendly NFC digital receipts solution for actionable shopper data and enhanced customer journeys. No App, Just Tap. With one-tap convenience, Pi-xcels unlocks omni-channel marketing opportunities and boosts performance for retailers with our customer intelligence platform.
• Woodstock — Woodstock is an investment app that allows to invest in US stocks.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• Hmcomm — Hmcomm is a provider of AI technology-based voice recognition and abnormal sound detection services for business applications. The company offers speech recognition / natural language processing solutions such as cloud-based voice recognition, text recognization in voice calls, bone conduction, automatic answering machine and meeting minutescreation, thereby enabling businesses to improve efficiency through technology.
• lafool — lafool is a mental health tech company that provides an organizational diagnostic tool "Laful Survey" to realize health management.
• earlyworks — Earlyworks Co., Ltd. provides blockchain technology solutions. The Company develops hybrid blockchain product that is fast and secure. Earlyworks offers software and system development, consulting, and security solution services.

Portfolio highlights

• RABO — RABO is a Cat-Tech Company that "watches cat life with technology.
• MICOLY — MICOLY is a operator of a website aimed at publishing and selling creative video lessons. The company hosts lectures that are presented by the creators of all categories who are keen on sharing their techniques and philosophies in areas of nail art, Japanese calligraphy, flower arrangement, knitting and many more, as well as interacting with theirpassionate fans, enabling users to take creative lessons and start a new hobby.
• Asoview — ASOVIEW Inc. is an online booking website that provides booking services for weekend leisure activities like skydiving and rafting. The company was founded in 2011 and is based in Shibuya, Kanagawa.

Portfolio highlights

• Argos — Argos provides the online insurance medical treatment service.
• Brainbuddy — Brainbuddy specializes in sales support, business growth, recruiting, consulting, and training services.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• ACCEL Stars — ACCEL Stars is a fitness and wellness firm that offers sleep diagnosis and examinations like sleep health, hygiene and medical devices.

Portfolio highlights

• EAGLYS — EAGLYS provides a platform for secure computing and AI.
• lafool — lafool is a mental health tech company that provides an organizational diagnostic tool "Laful Survey" to realize health management.

Portfolio highlights

• Castee — Castee provides social collaboration services and also helps with a tool for job requests and overseas projects for creators.
• Tribeau — Tribute is a word-of-mouth app for aesthetic medicine for cosmetic surgeries, cosmetic dermatologists, and orthodontists who are not covered by health insurance.
• Recustomer — Recustomer is an IT company that develops software for digital payment and provides support for web development.

Portfolio highlights

• MoonJapan — MoonJapan is an educational impact startup that offers a variety of programs and thorough assistance.
• Respo — Respo is a service that enables people to save money by buying things at a discount.
• Prefab — Prefab offers cutting-edge AI SaaS solutions tailored for the construction industry, enhancing efficiency, safety, and decision-making through data-driven insights.