Top 50 Wellness Startup Investors in Japan (October 2026)

Portfolio highlights

• Any Style — Any Style develops a messaging app from voice actors that regularly sends messages via subscription. It also engages in the planning and production of audio content and the VTuber production business.
• Arrowsmith — Arrowsmith is committed to unlocking the full potential of bacteriophages to revolutionize the treatment of bacterial infectious diseases. Through transformative science, Arrowsmith strive to create a world free from the pain and fear caused by antimicrobial resistance.
• Typewriter Therapeutics — Typewriter Therapeutics, Inc. develops mRNA-based gene therapies using a gene writing, or gene writing, platform for precise insertion of therapeutic genes into the genome. The company builds on transposon-based technologies originating from research by Professor Emeritus Haruhiko Fujiwara at the University of Tokyo. Its programs focus on all‑RNA,nonviral gene writing systems that repurpose natural genetic elements to address severe genetic disorders with limited treatment options. Typewriter Therapeutics conducts research and development across its U.S. and Japan operations and collaborates with investors and partners to advance genetic medicine candidates toward the clinic.

Portfolio highlights

• KUZEN — KUZEN provides enterprise-grade chatbot technologies, especially the bot framework and NLP, via a visual UI without coding. The company is utilizing technology to develop a system that broadens the scope of dialogue. They use technology to provide their customers with next-generation standard procedures that broaden the possibilities ofconversation, resulting in unprecedented business practices.
• AOI Biosciences — AOI Biosciences is a biotechnology company that creates testing and drug discovery businesses.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• Yoom — Yoom is a consulting company that offers system development services on AI, IoT, data solutions, and cloud integration.
• Ocean — Ocean is a technology-driven company dedicated to promoting digital transformation in the tax-free and retail shopping sectors. By developing innovative digital platforms and integrated solutions, the company streamlines tax refund processes and enhances the overall shopping experience for international travelers and retailers alike.
• TricoLogic — TricoLogic is a consultancy that offers technical code coaching, language skills training, and digital marketing services.

Portfolio highlights

• AI Mage — AI Mage is an IT company that provides AI solutions for anime production business industries.
• Umami United — Umami United is a plant-based food brand with unique focus on Japanese food technologies and traditional ingredients to make delicious and healthy food to unite people at one table. The wide lineups are designed to be vegan-friendly, buddhist friendly, and halal friendly for all.
• Gravity Design — Gravity Design is a full-stack platform consolidating supply chains for home interior materials.

Portfolio highlights

• Factory X — Factory X is an information technology company that helps to increase value manufacturers with the inventory strategy model.
• Quastella — Quastella develops quality control technologies for cell-based manufacturing and life science applications. The company provides systems for analyzing, recording, and managing cellular data using image-based evaluation methods. Its technology supports the construction and utilization of cell-related datasets, monitoring of cell states, comparisonof historical records, and quantitative assessment of cell quality. The company serves organizations engaged in biotechnology, regenerative medicine, and related research and industrial activities.
• New Space Intelligence — We provide Satellite data pipeline services and Remote sensing Satellite Solutions with AI, machine learning and Big data such as Change detection through optical and SAR time series data, crop pattern classification, Infrastructure monitoring.

Portfolio highlights

• Facilo — Facilo is a real estate communication provider that uses cloud computing to enhance sales and ease transactions of real estate brokerage.
• ARK — ARK specializes in the research, development, and manufacturing of land-based aquaculture equipment for sustainable fish farming.
• Intentia — Intentia is a technology startupspecializes in developing and implementing AI-driven workflow support tools and operational systems.

Portfolio highlights

• REVORN — REVORN is a fragrance AI and DX research and development company. They develop products such as odor sensors that can respond to odor issues and needs. They provide consultation at a range of levels, from identifying issues to developing solutions.
• Rutilea — RUTILEA is an IT company that aims to solve social issues through open-source. By advancing revolutionary 'AI teaching AI' concept, edefine automation, data-driven decision-making, and operational efficiency.
• LENZO — They are system architects and builders, committed to engineering high-performance, energy-efficient hardware for a new generation of workloads. They hold great expectations that Japan-based LENZO will drive a game-changing breakthrough with its innovative semiconductors and establish a strong presence on the global stage. Their proprietary CGLAarchitecture delivers breakthrough performance per watt in a compact, cost-effective form.

Portfolio highlights

• But Beautiful — A collaborative AI workspace, built on your company context. Build and orchestrate agents right alongside your team's projects, meetings, and connected apps.
• QueryLift — QueryLift provides software that analyzes AI-generated brand visibility and monitors generative AI security risks.
• Ocean — Ocean is a technology-driven company dedicated to promoting digital transformation in the tax-free and retail shopping sectors. By developing innovative digital platforms and integrated solutions, the company streamlines tax refund processes and enhances the overall shopping experience for international travelers and retailers alike.

Portfolio highlights

• bellFace — bellFace is an InsideSales System specialized targetted for Business to business sales customer support.No log in, no installation required. No matter where you are, it connects in 5 seconds becacuse it operates in the browser (patented). The audio system is connected through the telephone lines, there is no interruption like with Web meetingsystems. bellFace which is specific to sales, comes with document sharing and script function, so your experience is just like face to face communication . It is also suited for inside sales.
• WineBank — "WineBank" is a real-time online wine management and investment solution that we offer. In addition to operating a restaurant, it runs a sales company for food, drink, and other items.
• Mourning Clothes Rescue — Mourning Clothes Rescue operates a specialized clothing rental model utilizing automated, 24-hour unmanned storefronts. Users complete reservations and payments through smartphones to instantly access physical retail outlets via smart locks. This continuous availability solves the immediate challenge of acquiring formal attire on short noticeduring unexpected bereavement. By removing traditional staff overhead, the system passes cost efficiencies to consumers while providing private, on-site fitting options and long-term rental periods.

Portfolio highlights

• Space BD — Space BD aims to become a one-stop shop to respond to all issues related to industrialization of space, and alleviate the work of businesses that are developing new technologies.
• Hinoki — Hinoki is a business succession company that acquires small and mid-sized businesses for long-term ownership and supports their continued growth through management, technology, and talent investments.
• Bridgesmile Corporation — Bridgesmile operates an on-site installation and replacement service platform.

Portfolio highlights

• Caguuu — Caguuu offers high-quality designer furniture at affordable prices, through e-commerce, eliminating middlemen and store operating costs.
• Smart Craft —
• Link Therapeutics — Link Therapeutics specializes in developing therapeutic methods for targeting autoantibodies and identifying pathogenic autoantibodies.

Portfolio highlights

• Meesho — Meesho operates as an online reselling platform that enables anyone to start a business without investment. Meesho is a business platform trusted by more than 2.6 million resellers across India. The company was founded in 2015 by Vidit Aatrey and Sanjeev Barnwa and is headquartered in Bangalore, Karnataka.
• Pine Labs — Pine Labs offers a merchant platform that includes technology and financial solutions for merchants. These solutions are aimed at helping merchants in increasing their revenue and reducing cost, complexity, and risk.The company connects financial institutions and consumer brands to enable merchants to deliver value to their retail customers. Itpowers offline and online last-mile retail transactions, provides customer insights for targeted sales, and offers financial solutions. The company’s cloud-based platform powers 3,50,000+ POS terminals across 3700 cities and towns in India and Malaysia.Over 1,00,000 merchants across sectors - electronics, food and beverage, fashion, airlines, and more, use Pine Labs’ solutions. 15 major banks, 7 financial institutions, and 100+ brands are part of Pine Labs’ platform.
• Quintessent — Quintessent is developing optical connectivity solutions to scale computing and Artificial Intelligence (A.I.).

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• AnotherBall — AnotherBall is a blockchain startup that combines entertainment and blockchain.
• SBX Corporation — AI R&D: Deep learning, Machine learning, Automation, Text mining. Development, customization and maintenance of software platforms for drug discovery and life science research.

Portfolio highlights

• Yondemy — Yondemy is an online platform for children reading books.
• Yokohama Vanilla — Yokohama Vanilla is a Company which operates Yokohama-based gift sweets brand.
• Zeal Boxing Fitness — Zeal Boxing Fitness combines power of sports with the power of technology to provide a service that allows to enjoy fitness.

Portfolio highlights

• LQUOM — QWAVE offers cryptography communication technology.
• Alxtal — Alxtal is a tech company who optimize the development, design, and manufacturing processes of the manufacturing industry with IT and AI.
• Direava — Direava is a medical device company that manufactures, sells, leases, and maintains medical equipments along with consulting services.

Portfolio highlights

• 10pct. — 10pct. is a consulting firm that provides hotel management, marketing, and operation support services to its clients.
• Sharing Energy — Sharing Energy is providing energy supply and energy management services.
• Monochrome — Monochrome is creating a home operating system in order to power the next generation of energy-producing homes and roofs. The company is based in Chuo Ward, Tokyo.

Portfolio highlights

• Recri — Recri works for the entertainment industry and specializes in operations management tasks like ticketing for stage, film, and music shows.
• Letara — Letara operates a space technology platform with the intention to serve a logistics network covering the solar system. The company produces hybrid propulsion engines for small spacecraft, promoting groundbreaking advances in space propulsion with high thrust, safe, and inexpensive propulsion system technology.
• AI Mage — AI Mage is an IT company that provides AI solutions for anime production business industries.

Portfolio highlights

• Torihada — Torihada is a creative firm specializing in influencer marketing, creating content, and digital marketing.
• xxxxnese — xxxxnese is a logistics company that focuses on import, export, domestic sales, influencer marketing, and software development businesses.
• ZIRITZ — StockFormer is a real estate investment platform that connects investors with property opportunities. Users can calculate their asset score and gain a better understanding of their position and status as an investor, as well as their creditworthiness to financial institutions, among other things. Investors can exchange information on purchased andsold properties, as well as loan terms. The log provides investors with an understanding of the current real estate market conditions, investment conditions, and loan conditions that correspond to their asset formation level, allowing them to make appropriate investment decisions.

Portfolio highlights

• JPYC — JPYC is a financial institution that issues the community stablecoin JPYC, which is pegged to the yen of Japanese. They want to create a society where everyone can develop by fusing the real world with the world of cryptocurrencies and increasing the liquidity of capital to achieve their goal of overcoming the social conundrum. It will promotecapital's liquidity and create an environment that helps in development for all.
• Terass — TERASS is a High-end real estate information site.
• LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.

Portfolio highlights

• ARK — ARK specializes in the research, development, and manufacturing of land-based aquaculture equipment for sustainable fish farming.
• Gaxi — Gaxie is an IT firm that provides a cloud management system and manages scholarship sites for business.
• Factory X — Factory X is an information technology company that helps to increase value manufacturers with the inventory strategy model.

Portfolio highlights

• Sazo — Sazo specializes in constructing a global e-commerce and logistics network with AI.
• Dioseve — Dioseve is providing novel possibilities for all life.
• Genba Hub — Genba Hub specializes in providing business management systems for construction and maintenance enterprises.

Portfolio highlights

• WAKA — WAKA is a studio that produces metaverse games and specializes in contract development for domestic businesses.
• Rehabilitation 3.0 — Rehabilitation 3.0 focuses on a preventive medical system that provides AI assessment and tracking on health, exercise, mood, and wellness.
• Movus Technologies — Movus Technologies Indonesia is automotive company that provides car ownership rental services.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• AstroX — AstroX is a private space startup company that develops satellite launch vehicles for space development. It utilizes the rockoon method for developing launch vehicles and small rockets to help clients easily use space.
• Sonire Therapeutics — SONIRE Therapeutics Inc. (SONIRE) is working on a next-generation high-intensity focused ultrasound (HIFU) therapy system that will employ acoustic engineering (ultrasound) technologies developed through cutting-edge academic research. SONIRE has been working on a next-generation high-intensity focused ultrasound (HIFU) treatment system as a noveltherapeutic modality with the goal of giving cancer patients and their families a new future.

Portfolio highlights

• Comvey — Comvey provides a shopping experience that is friendly to people and the earth. It primarily offers a foldable share bag online.
• SoVa — SoVa operates an accounting firm that combines technology and experts.
• Irori — Irori blends online and offline spaces, supporting creators and new projects with platform models and sustainable growth.

Portfolio highlights

• CADDi — CADDi analyzes and connects manufacturing data fragmented across departments, locations, and systems, turning it into an enterprise asset. It uses AI to transform how manufacturers make decisions and execute work.
• Facilo — Facilo is a real estate communication provider that uses cloud computing to enhance sales and ease transactions of real estate brokerage.
• kikitori — kikitori engages in the development and operation of applications and web systems in the fruit and vegetable distribution field.

Portfolio highlights

• Naorai — Naorai is a food and beverage firm that manufactures wine, beer, spirits, and non-alcoholic beverages.
• Sinumy — Sinumy develops touchless identity authentication technology and high-speed, high-precision position measurement technology.
• Dioseve — Dioseve is providing novel possibilities for all life.

Portfolio highlights

• CaTe — CaTe is based in Tokyo. CaTe develops and manufactures a Digital Therapeutic (DTx) for remote cardiac rehabilitation. Their invention allows heart disease patients to safely and successfully complete cardiac rehabilitation utilizing standing exercise in a confined space, such as at home, without the use of ergometers or similar instruments.
• AIONA — AIONA uses AI to produce high-quality products and provides everyone with access to knowledge.
• Yoom — Yoom is a consulting company that offers system development services on AI, IoT, data solutions, and cloud integration.

Portfolio highlights

• OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
• Eight Knot — Eight Knot is a developer of autonomous navigation systems intended for water mobility. They provide autonomous ship maneuvering technology using robotics, enabling customers with water-on-demand transportation using environment-friendly EV robotic boats.
• Zeal Boxing Fitness — Zeal Boxing Fitness combines power of sports with the power of technology to provide a service that allows to enjoy fitness.

Portfolio highlights

• Porty — Porty is a real estate platform company that provides property search tools, urban housing services, and data-driven solutions.
• PG Labs — PG Labs is a Web3 studio that upholds the philosophy of "Public Goods".
• Pheasant Network — AI-Powered DeFi Super App for Cross-chain Intent.

Portfolio highlights

• Nehan — Nehan is a software firm that offers AI bidding information and a media outlet that delivers to local government businesses.
• Insight Core — Insight Core is a store promotion specialized application platform service. With no upfront costs, InsightCore creates customer-attracting apps tailored to various business categories such as apparel, restaurants, and retail. InsightCore develops the functions required for the store application and prepares a mechanism that allows the functions tobe implemented with the least amount of effort.
• Omatsuri Japan — Omatsuri is Japan's first festival company specializing in Japan.We provide planning, management, promotion, and customer support for festival organizers from local governments to store associations.

Portfolio highlights

• Sazo — Sazo specializes in constructing a global e-commerce and logistics network with AI.
• Vitom — Vitom is a FoodTech startup that addresses the issues of sustainability and reliability in the food industry.
• CrossVision — CrossVision offers solutions and services specific to the VTuber market.

Portfolio highlights

• Takadao — Takadao builds technology that enables communities to pool money together to mutually insure one another without the need for an insurance company.
• Meme — MEME is a money app for parents and children to make money more familiar and simplifies the flow of money.
• EduCare — EduCare provides affordable solutions to financial assistance for giving education to students.

Portfolio highlights

• Ababa — Ababa provides recruitment and employment solutions.
• Pick You — Pick You offers a marketplace that facilitates seamless purchase of items directly from popular Instagram users.
• Tenchijin — Tenchijin is optimiz human civilization using space big data.

Portfolio highlights

• Ubiden — Ubiden provides Artificial intelligence and Internet of Things mobile network services. The company develops applications for electric vehicle charging services.
• SDP Japan — SDP Japan is a provider of super Doctor Produce Business and procurement and sales of surgical components, pharmaceuticals, and consumables.
• Terra Charge — Terra Charge offers EV charging infrastructure business, EV charger installation proposals, installation work, operation, and maintenance.

Portfolio highlights

• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
• Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
• MinD in a Device — MinD in a Device Co., Ltd. is a university-launched venture that aims to port human consciousness to devices (machines and computers) in the medium to long term based on long-term research results on consciousness. As the first step toward realization, we will evolve and deepen the "generation model" considered to be the source ofconsciousness, and promote the development of next-generation AI and social implementation.

Portfolio highlights

• Opt Fit — Opt Fit is a fitness industry that provides fitness, wellness and health-care services.
• Voxela — Voxels is an AI powered platform on a mission to reinvent caregiving by making incident detection intelligent and actionable.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.
• Mediclo — Mediclo is a real estate company that provides renting, property management, and B2C services.
• Otetsutabi — Otetsutabi is a regional revitalization platform that offers the opportunity for participants to help at accommodations and breweries in rural areas that struggle with seasonal labor shortages. The locals offer transportation expenses and places to stay in return, so participants can travel to the areas with ease.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• Co-nect — Co-nect is a Body maintenance is a Body maintenance service platform.
• Wamazing — WAmazing provides free subscriber identification module (SIM) cards that allow foreign travelers to register before their arrival in Japan. Through an app, WAmazing also provides tourists with free internet services of up to 500MB. The service aims to prevent visitors from being locked out of free wifi because of sign-up pages in Japanese thatdemand a local phone number.WAmazing was founded in 2016 and is based in Tokyo, Japan.
• CO-NECT — CO-NECT is a cloud-based online ordering system designed to let users place and receive orders anytime.

Portfolio highlights

• Henry — Henry develops and provides a cloud-based electronic medical record and receipt system for small and medium-sized hospitals.
• Ruten — Ruten is a brain-machine interface company that specializes in reconstructive treatments for infeasible and ineffective conditions.
• Tokenz — Tokenz is your all-in-one platform for global digital payments, cross-border tax compliance, and seamless payouts.

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• RE — RE specializes in smartphone application design and development.
• Vitalogue Health — Vitalogue Health is a hormone testing service intended to provide access to hormones and medical care. They allow users to self-check the physical condition for pregnancy and how hormones affect it, whether the symptoms are related to menopause, and provide personalized test results, commented on by physicians.

Portfolio highlights

• LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
• Metcela — Cells hold endless possibilities. Through science, we will unlock these potentials and harness them to improve the lives of patients worldwide.
• Hirosaki Lifescience Innovation — Hirosaki Lifescience Innovation is engaged in the development, manufacture, and sale of regenerative medicine products.

Portfolio highlights

• Bravia — Bravia is a planned joint-venture company for Sony and TCL home entertainment products.
• Rapidus — Rapidus is an Electronic component research, development, design, production, and sales that includes semiconductor elements and integrated circuits. Environmentally friendly, energy-saving semiconductors and semiconductor manufacturing technology are being researched and developed. Human resource development and training for the semiconductorsector.
• Kadokawa Corporation — Kadokawa Corporation is a comprehensive entertainment company that includes publishing, video, games, Web services, education, MD, and business for inbound customers, as well as products and services through the promotion of digital transformation, including activity-based working and global intellectual property expansion.

Portfolio highlights

• Morght — Morght is an information technology service company.
• Nanameue — Nanameue creating a new future that makes people smile and has a fun experience. Create your own place by connecting people to people in “nanameue” way.
• Hogetic Lab — Hogetic Lab specialize in DCaaS, AI development, and Data human resources training.

Portfolio highlights

• Argos — Argos provides the online insurance medical treatment service.
• Brainbuddy — Brainbuddy specializes in sales support, business growth, recruiting, consulting, and training services.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• BABY JOB — BABY JOB offers nursery support and child care support businesses.
• GoFood — GoFood operates an online food delivery service providing healthy and sugar-restricted frozen foods for a healthy lifestyle. The company aims to make daily home meals easier, more delicious, and healthier. It was founded in 2019 and is based in Tokyo, Japan.

Portfolio highlights

• Wakaze — Wakaze is a supplier of craft sake beer. They provide products that include beer, other alcoholic beverages, food products, snacks, and drinks. They provide products that are available for online shopping. An online inquiry form is available on the company's website.
• Cogsmart — Cogsmart provides services for brain function research and development. In hopes of helping prevent dementia and maintain and improve other cognitive functions, they manufacture and sell software for medical and healthcare devices.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .