Top 50 Medical Device Startup Investors in Japan in May 2026

Portfolio highlights

• Innovacell — Innovacell is a biotechnology firm entirely focused on the area of tissue engineering and it operates one of Europe's largest and most modern production facilities for the proliferation of the body's own tissue cells. Its supervisory board is chaired by the experienced financial expert, Dr. Harald Pöttinger, a director of Alpine EquityManagement AG, based in Bregenz, Austria. Innovacell currently employs 20 staff as well as numerous outside experts.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.
• Blue Whale Energy — Blue Whale Energy connects and optimises distributed batteries across Singapore, helping businesses and solar developers unlock new revenue streams while supporting a cleaner, more reliable grid.

Portfolio highlights

• Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
• Upward — UPWARD is highly by linking CRM · schedule map / location information, is a cloud service for the visiting business of field sales easier. Field salespersons who have many customers and who are out of the office feel that it is difficult to grasp all customers to Kampek and measure the timing of visits no matter how memorable they are.
• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.

Portfolio highlights

• Superworm — Superworm is a producer of environmentally friendly and long-term solutions to societal challenges. The company undertakes genome editing research and sells protein powders, biofuels, and organic fertilizers made from superworms, allowing customers to consume insect-derived proteins and biofuels.
• Japan Agriculture — Exportation of Japanese agricultural products is currently small in volume. While Japanese farmers aspire to export their products to foreign countries for more people to enjoy and local consumers universally share the positive perception of the quality of Japanese agricultural products, issues such as price, communication, and logistics hinder theexpansion of exportation.They aim to solve these issues and satisfy the needs of both Japanese farmers and global consumers which are so clearly evident but devastatingly unmet.
• Bluefield Energy — Bluefield Energy redefines Japan's electricity sector through technology-driven renewable energy solutions. Its mission centers on liberating people and society from energy constraints by tackling high costs, environmental impact, and supply instability.

Portfolio highlights

• CREO Bioscience — Cleo Bioscience is a Biotechnology company.
• Global Trust Networks — Global Trust Networks is a company that helps foreigners to live in Japan
• Fabric Tokyo — FABRIC TOKYO is a Japanese startup provides a direct-to-consumer custom-made apparel brand. (former-company name Lifestyle Design Co., Ltd.). It enables customers to save their sizes, idea fabrics, and favorite designs, allowing them to make their original clothing later.FABRIC TOKYO was founded in 2012 by Yuichiro Mori and is based in Tokyo,Japan.

Portfolio highlights

• Space quarters — Space Quarters is a manufacturing company that produces payload deploy and panels, and develops space assembly robotic systems.
• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• Ichirou — Ichirou provides digital senior care support services to connect elderly people with caretakers. It offers caretaker services for different types of support, including housework, hospital care, nursing, hospital and doctor visits, and shopping assistance.
• RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• RoboTruck — RoboTruck develops autonomous driving technologies for huge trucks, as well as practical applications.
• Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

Portfolio highlights

• QREATION — QREATION is a digital intellectual property studio specializing in producing a wide range of popular content that originates primarily from social media platforms. The company focuses on creating high-quality short-form entertainment, including short dramas, comedy sketches, and variety shows.
• Forward — Forward is a SaaS-based startup that offers recruitment agency services.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
• Aerem — Make the switch to rooftop solar effortlessly with Aerem solution's innovative solar finance and technology solutions. Discover how we're making solar adoption easier than ever before and start saving on your energy costs.
• Power Wave — Power Wave seeks a carbon-neutral world using wave technology for wireless power, tackling global warming and fuel depletion.

Portfolio highlights

• Fivot — Fivot is a financial company that provides venture capital, financing, credit, money lending, and prepaid payment services.
• MODE — With offices in both San Mateo, California, and Tokyo, Japan. The company is rapidly growing with now over fifty employees and is in business to provide end-to-end semi-custom IoT and AI solutions for organizations to improve their operations by connecting them to their data, giving them “real-time” insights, so they can turn innovative ideas intosustainable solutions that address a wide range of challenges.Simple, yet powerful, our latest "next generation" BizStack IoT and BizStack AI solutions are comprised of a continuous improvement technology stack that collects real-time data from any sensor, device, product, equipment, or legacy system. The data is then sanitized, uniquely structured, and provided to highly customizable, intuitive dashboards with powerful insights, along with proper security in the cloud for ongoing IoT and AI applications.BizStack can be deployed 4X faster and 75% less expensively than in-house developers or outside consultants.
• OPTEMO — OPTEMO develops and supplies sales technology that allows businesses and customers to connect through a website.

Portfolio highlights

• FELIQS — FELIQS is a preclinical-stage start-up company established based on the robust science from molecular pathobiology, department of pharmaceutical science, Kyushu university.
• ATOMica — ATOMica is a co-working space and business management company for conference rooms, event venues, circles, and schools. The company uses coworking spaces as HUBs to provide services that maximize individuals' power. It can be used for a variety of purposes, including coworking space, shared office space, meetings, events, and web seminars. Itis also possible to use it only once. They plan and run local communities that bring together a diverse range of people, including students, workers, businesses, universities, and governments.
• OPTEMO — OPTEMO develops and supplies sales technology that allows businesses and customers to connect through a website.

Portfolio highlights

• Ripcord — Ripcord is a robotics company that combines hardware and software robotics via an integrated SaaS offering. Its focus is on smart robotics digitization, smart content management with AI, and helping enable RPA and business processes.Ripcord is based in Hayward, California, and is backed by leading investors Kleiner Perkins Caufield & Byers,Google Ventures, Lux Ventures, Legend Star, and Apple Co-Founder Steve Wozniak.
• 24M Technologies — 24M Technologies develops energy storage systems for grid and transportation applications. 24M Technologies, Inc. builds energy storage systems for grid and transportation applications. The company was founded in 2010 and is based in Cambridge, Massachusetts.
• Tome Biosciences — Tome Biosciences is a biotechnology company that develops programmable gene insertion technology. Using CRISPR, its technologies allow them to insert any genetic sequence of any size at any location into any genome.

Portfolio highlights

• ANSeen — ANSeeN Inc. - X-ray COLOR Imaging
• GAIA BioMedicine — GAIA BioMedicine Inc., a spin-out venture from Kyushu University founded on 2015, is a technology-driven biopharmaceutical company focusing on cellular therapies and immunotherapies mainly for intractable malignancies.
• Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).

Portfolio highlights

• Morus — Morus is a university-based biotech startup developing functional food ingredients from silkworms to address global health and nutrition challenges.
• FunPep — FunPep is an Industry-university collaboration bioventure company.
• AI Silk — AI Silk are innovative conductive fibers produced with a dyeing technique. By using natural silk and giving conductivity to the fiber itself, They have succeeded in producing electrodes that reduce some of the risks and challenges of conventional medical electrodes, which can cause discomfort,skin and in vivo inflammation, and measurement failuredue to sweat or other elements. Their brand, AI Silk, is a new material that has strong and diverse application potential, even beyond the health / medical field.

Portfolio highlights

• Ubitus — As cloud gaming enablers, Ubitus' GPU virtualization, Streaming technology and hybrid cloud deployment can serve different kinds of solutions for Telco, Game companies to quick enter cloud gaming market. Moreover, Ubitus provide Global distribution and New Media content solution for new media studio and fashion brand to help them distribute rich media contents worldwide.
• Drivezy — Own the Experience, not the Car
• Address — ADDress is a provider of co-living spaces in both urban and rural areas, enabling people to live in a range of luxurious residences at fixed prices.

Portfolio highlights

• G-ant — G-ant runs the MITACLE BLOCK service, transforming 2D illustrations into custom 3D block figures using voxel technology.
• MoonJapan — MoonJapan is an educational impact startup that offers a variety of programs and thorough assistance.
• Prefab — Prefab offers cutting-edge AI SaaS solutions tailored for the construction industry, enhancing efficiency, safety, and decision-making through data-driven insights.

Portfolio highlights

• 3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
• THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
• Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.

Portfolio highlights

• SOUNDRAW — Your personal AI music generator.
• Inter — Inter delivers solutions for global difficulties using vacuum technology, which uses a particular check valve to maintain a 99.5% vacuum rate.
• Better Place — Better place vision is to create a world in which kind people can continue to be kind, as well as a society in which people can work in their own way without worrying about money.

Portfolio highlights

• India Chip — India Chip is formed to manufacture and designed for a capacity of 20,000 wafers per month and can produce 36 million display driver chips.
• indiGO Tech — Indigo Technologies is transforming the way the transportation industry moves people and things.As the world becomes more crowded and resources are in greater demand, we’re faced with never-before-seen challenges. Indigo turns those challenges into opportunities. Our experienced team is driving the world forward in automotive technology andenergy.
• Neteera — Neteera's FDA-clear contactless RPM platform transforms patient care by accurately monitoring heart rate, respiratory rate, and behavioral parameters.

Portfolio highlights

• Unocoin — Unocoin a cryptocurrency exchange in India, offers seamless trading of Bitcoin & other cryptos. With 2M users Since 2013. Join India's trusted crypto platform.
• Kava Labs — Kava is a lightning-fast Layer-1 blockchain that combines the two most used permissionless execution environments into a single, scalable, developer-optimized network.
• Triple W Japan — Triple W develops DFree, the first wearable device for incontinence that can track the progression of bladder movements using a non-invasive ultrasonic sensor. The device will help elderly and disabled people who suffer from incontinence by notifying when they will need to go to the bathroom. DFree is now widely marketed in Asia and Europe and usedin over 500 senior care facilities. Triple W has offices in Japan, France, and the US.

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• Knowhere — Knowhere is a company that applies high-performance AI to sports.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• Alumnote — The alumni association management software developed by Alumnote allows schools to manage their alumni associations online. The focus of the company is to undertake loyalty building and marketing for potential donors such as graduates and provides digital tools, and supports the execution of donation acquisition.
• SkyDrive — SkyDrive is a start-up for development,manufacturing,sales of the “Flying cars” established by CARTIVATOR members.
• NABLA Mobility — Solving the complexities involved in the "Operation of Fleets" of Mobility and support its evolution and decarbonization

Portfolio highlights

• Eco-Pork — Eco-Pork is a co-creation solution farm that supports farmers' food productivity improvement. It is connecting the pig and technology, pork ( Pork ) new business ecosystems ( Ecosystem By building a), in the pork growing demand around the world, to get the most out of the food supply capacity is finite.
• Brainbuddy — Brainbuddy specializes in sales support, business growth, recruiting, consulting, and training services.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
• Thinker — Thinker provides sales of proximity sensors and proposed solutions using these products.
• Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.

Portfolio highlights

• Anaguma — Anaguma handles business development based on the philosophy of helping people with a sustainable structure. The company's business objective is to eliminate concerns about purchases and reservations, and it delivers before-sales social networks. It also provides matching services exclusively for housekeepers' personal contracts. Thecompany also offers influencer marketing services with a focus on removing waste completely from advertising and realizing a world in which good products can be sold regardless of advertising costs.Anaguma was founded in January 2016 and is headquartered in Tokyo, Japan.
• Ageless — Ageless is a staffing agency that provides human resources-related services primarily to middle-aged and senior citizens.
• Forest — Forest Co., Ltd. operates as an e-commerce aggregator, seeks to identify sustainable, high-quality products and brands that embrace the spirit of Japan and help them grow and enter the global market by using the power of technology.

Portfolio highlights

• MOVeLOT — MOVeLOT is an AI company that provides skeletal platform and robot planning, development, and production services.
• Kisui Tech — Kisui Tech is an agricultural AI robotics company that help farmers for farming.
• LYMPHOGENiX — LYMPHOGENiX is the pioneer company for lymphatic vessels regeneration. Our proprietary technology revitalizes the function of lymphatic vessels, making us experts in treating various health conditions. Our treatment is also great for skin-aging, obesity, Alzheimer's diseases and infertility. We believe in helping our clients improve their vitality and energy, one treatment at a time.

Portfolio highlights

• F.MED — F.MED is a manufacturing company that designs and develops robotic microsurgical devices for the healthcare industry.
• BioPhenoMA — BioPhenoMA develops an AI-powered platform for detecting ultra-trace proteins that helps accelerate new drug discovery phases.
• Spiral — Spiral is a game changer in providing autonomous drone solutions for indoor environments, most notably during non-GPS situations.

Portfolio highlights

• LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
• Metcela — Cells hold endless possibilities. Through science, we will unlock these potentials and harness them to improve the lives of patients worldwide.
• Hirosaki Lifescience Innovation — Hirosaki Lifescience Innovation is engaged in the development, manufacture, and sale of regenerative medicine products.

Portfolio highlights

• Alivas — Alivas is a medical company that develops new therapeutic medical devices for refractory constipation. It is a joint venture between Stanford University and the University of Tokyo with the Japan Biodesign program for innovative medical device creation. The company was founded in 2017 and is based in Hongo, Tokyo in Japan.
• PaMeLa — PaMeLa is a company that measures pain with science.PaMeLa will establish a method of objectively assessing pain and contribute to medical care.
• SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.

Portfolio highlights

• Tacoms — CAMEL is a service that allows you to easily manage orders from multiple food delivery / takeout services on a single tablet.
• Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
• Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Portfolio highlights

• KAICO — KAICO is a pharmaceuticals, diagnostic drugs production company.
• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
• Bluefield Energy — Bluefield Energy redefines Japan's electricity sector through technology-driven renewable energy solutions. Its mission centers on liberating people and society from energy constraints by tackling high costs, environmental impact, and supply instability.

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• Ana Neo — Ana Neo is a digital lifestyle and mobile gaming platform that provides a virtual entertainment experience.
• Swivel — Swivel's mission is to create the fishing brand.

Portfolio highlights

• AdipoSeeds — Making Platelets from Fat and Inventing New Blood Supply System.
• Green Card — Green Card s a company in Fukuoka that runs Junior Soccer NEWS and youth soccer cheering teams.
• KabuK Style — KabuK Style provides services that combines co -working spaces, accommodation facilities and cafes.Our service will be started from Nagasaki and We aim to expand the services all over the world.

Portfolio highlights

• Moova — Moova is a technological platform that captures idle last mile logistic capacity and transforms it into high efficiency and low cost shipping solutions. The platform connects E-Commerce and retail businesses with a fleet of "Moovers" who complete deliveries on their bicycle, motorcycle, car or van to generate an additional source ofincome. Through route optimization software, real-time traceability, flexible warehousing, and analytics, Moova is propelling the nascent E-Commerce industry in Latin America by reimagining the last mile for a sustainable world.
• LIGHTz — LIGHTz delivers a technology transfer and information exchange platform leveraging AI.
• May Mobility — May Mobility is a leader in autonomous vehicle technology development and deployment. With more than 275,000 autonomous rides to date, May Mobility is committed to delivering safe, efficient and sustainable shuttle solutions designed to complement today's public transportation options. The company's ultimate goal is to realize a worldwhere self-driving systems make transportation more accessible and reliable, the roads safer, and encourage better land use in order to foster more green, vibrant, and livable spaces.

Portfolio highlights

• Scimplify — Scimplify delivers innovative specialty chemical solutions as a trusted manufacturer and global supplier to industries including pharma, food, and cosmetics
• EF Polymer — EF Polymer Private Limited providing 100% Organic and fully Biodegradable Super Absorbent Polymer cum Fertilizer to reduce Water and Fertilizer requirement for your plant. Let's grow organically.
• iMicrobes — We are a synthetic biology company on the mission to work with the world's largest companies to use new raw materials and recycle waste for chemical production, polymers, agriculture, and space exploration.

Portfolio highlights

• Fermelanta — Fermelanta produces rare plant-based ingredients through microbial fermentation. It engineers a cell to build a biosynthetic pathway of target molecules with gene transfer and disruption.
• Goals — Goals specializes in development, sales and operational support for cloud services for food service companies.
• Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.

Portfolio highlights

• HITOTSU — HITOTSU is a software development company that provides medical device management systems for all hospitals and clinics.
• Miresso — Miresso is a startup firm that offers nuclear fusion power generation services through natural resources.
• StoryHub — StoryHub is a powerful all-in-one AI editing assistant designed to help users create high-quality content quickly, efficiently, and at a significantly lower cost. Whether you're drafting blog posts, polishing articles, scripting videos, or refining marketing copy, StoryHub streamlines the entire content creation process with intelligent tools

Portfolio highlights

• JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.

Portfolio highlights

• Team T5 Inc. — TeamT5 is a professional cyber security solution provider. Compared with other cyber threat intelligence (CTI) vendors, TeamT5 has the deepest understanding of cyber espionage in the Asia-Pacific region. Our world-class research team has dedicated to malware research and security incident response for more than 10 years. With solid technicalbackground and frontline expertise, our portal ThreatVision delivers the best CTI, and ThreatSonar offers the most effective APT hunting solutions. With TeamT5, you are able to being ahead of your threats.
• NEXTAGE — Nextage is an Agri-tech company that offers wasabi cultivation in a container.
• Save Medical — Digital Therapeutic company for Japan market. First product is for Type 2 Diabetes patients.

Portfolio highlights

• INDX — Unstructured data support, AI utilization without exposing confidential data, rapid implementation. Extensive experience in manufacturing, finance, and healthcare. Provide company-specific AI solutions with custom tuning.
• Paytner — yup is providing services to support freelance people's funding.The freelance population in Japan has been shown to continue to increase in many Chosa. While working styles are diversified, they are not able to respond to the development of the working environment, and they will develop their business to change the situation where problemssuch as funding, credit, sexual harassment, and power harassment are accumulated.
• Mjolnir Spaceworks — Mjolnir Spaceworks desings and manufactures state-of-the-art novel space rockets with efficient engines as well as other space equipments.

Portfolio highlights

• Marugoto — Marugoto is a human resource company that engages in offering recruitment support and back office services.
• Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.
• Interstellar Technologies — Interstellar Technologies is a rocket development, manufacturing and launch service.

Portfolio highlights

• WELMO — WELMO has currently been working on R&D to launch Japan's largest welfare AI service platform called "CPA(Care Plan Assistant)" which supports care coordinator (caregiver), who helps a daily activities of the elderly people, to create a care plan for them, with using ICT and advanced technology, especially NLP(Natural LanguageProcessing), in terms of knowledge support. It has mainly two fundamental technologies; data warehouse includes all fast date and big date about care, explainable AI that describes a reason why the care is provided for the users. It also reduces time and cost to create the care plan, which enables anyone to be able to use easily and get enough information that the users want to know and use.
• CROSS SYNC — The company was founded in October 2019 by Dr. Takaki, a Japanese intensivist with more than 20-year experience in critical care medicine, from his strong desire of wanting to decrease preventable death and sudden changes in patient conditions while in the ICU. CROSS SYNC’s vision is to provide ICU-level medical treatment anywhere. The mission isto help and assist medical professionals utilizing the power of technology so that they can provide high-quality medical care even in an environment where there is a shortage of specialist physicians, and to ensure the best patient outcomes. As a Yokohama University certified startup, CROSS SYNC develops a variety of AI clinical assistant tools in collaboration with affiliated hospitals, the school of medicine, and the department of health data science. By delivering our AI-based platform to acute care settings all over the world, we aim to create a world without avoidable deaths and preventable acute changes for in-patients.
• Ispace Technologies — ispace is a private lunar robotic exploration company that is developing micro-robotic technology to provide a low-cost and frequent transportation service to and on the Moon, conduct lunar surface exploration to map, process and deliver resources to our customers in cislunar space.

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• Anyplace — Find furnished accommodations to rent for a month or longer. Choose apartments catered for remote work with an equipped home office and high-speed internet.
• Firstcard — All-in-One Student Credit Builder. Build credit. Earn cashback. Grow your deposit.

Portfolio highlights

• AGRIST — AGRIST Co., Ltd. is a venture company that solves agricultural problems with technology. An automatic harvesting robot solves the problem of a shortage of farmers who are aging and harvesting agricultural products.
• AMI — AMI Corp is engaged in medical consulting, medical device development and writing.
• MabGenesis — MabGenesis is a biopharmaceutical company that provides therapeutic monoclonal antibody drugs in human and animal fields.

Portfolio highlights

• AGREE — AGREE is an application developer and operator for medical consultation. Its product is the medical consultation application, LEBER. It allows its users to consult with a doctor on their smartphone 24/7. It was founded in 2017 and is headquartered in Tsukuba, Ibaraki Prefecture, Japan.
• SmartScan — SmartScan is a Japanese company that manufactures preventive medicines. SmartScan's mission is to create and provide an image screening environment that is easy for anyone to visit.
• Kringle Pharma — Kringle Pharma, Inc., a biopharmaceutical company, develops pharmaceutical products based on its research on hepatocyte growth factor (HGF) and NK4. Its HGF has the regenerative healing ability in regard to liver cells, as well as various cells and organs; and NK4 is a bi-functional molecule, which inhibits the invasion and metastasis of tumorcells as an HGF-antagonist, as well as possesses antiangiogenic activity. The company’s pipeline includes recombinant human HGF for the treatment of acute renal failure, skin ulcers, and CNS diseases; and recombinant human NK4 and NK4 gene drugs for cancer therapy. Kringle Pharma, Inc. was founded in 2001 and is based in Toyonaka, Japan.

Portfolio highlights

• Repro — Repro is a mobile analytics tool that offers insights into mobile app users through play-by-play videos of their behavior. It was launched in 2014 and is operated from Tokyo, Japan.
• HoloEyes — HoloEyes plans to use the funds raised this round to build the system and business base for HoloEyes VR and expand its staff.Collecting the data from CT scans, forming 3D human body models, and accumulating it creates a so-called medical VR database.
• InstaVR — InstaVR has been selected by over 50,000 companies and professionals. No-Coding, Web Browser based, Interactive Authoring Tool allows you to make and publish interactive 360 images / video based VR

Portfolio highlights

• OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
• FerroptoCure — FerroptoCure is a research firm that specializes in ferroptosis research and the development of therapeutic drugs to treat diseases.
• RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Portfolio highlights

• Caulis — Caulis is a cybersecurity company building the open security platform for every single device.
• Oh My Glasses — Oh My Glasses TOKYO is a lifestyle brand that offer high quality made in Japan eyewear at an affordable price.Oh My Glasses has been providing an eyeglass e-commerce service that offers five sets of eyeglasses at a time upon order, and buy one if you can find any favorite among them. So customers can try them on before buying.
• Triple W Japan — Triple W develops DFree, the first wearable device for incontinence that can track the progression of bladder movements using a non-invasive ultrasonic sensor. The device will help elderly and disabled people who suffer from incontinence by notifying when they will need to go to the bathroom. DFree is now widely marketed in Asia and Europe and usedin over 500 senior care facilities. Triple W has offices in Japan, France, and the US.

Portfolio highlights

• LPIXEL — LPIXEL hones its expertise in the life sciences and image analysis technologies, congregating data from the medical, pharmaceutical and agricultural sectors to shape the coming future. LPIXEL will serve as a hub for open innovation, expand its expertise acquired from the world of research, provide a prosperous future and deliver revolutionary products. With this belief in mind, LPIXEL is on a continuous journey to make the world a happier place for everyone.
• Eximis Surgical — Eximis Surgical is developing an enabling technology that allows surgeons to quickly remove large specimens through small incisions. Its technology uses RF energized cutting wires temporarily held in place within a containment bag. It was founded in 2014 and headquartered in Louisville, Colorado.

Portfolio highlights

• LPIXEL — LPIXEL hones its expertise in the life sciences and image analysis technologies, congregating data from the medical, pharmaceutical and agricultural sectors to shape the coming future. LPIXEL will serve as a hub for open innovation, expand its expertise acquired from the world of research, provide a prosperous future and deliver revolutionary products. With this belief in mind, LPIXEL is on a continuous journey to make the world a happier place for everyone.
• Riverfield — Riverfield is a Japanese start-up that develops robotic technology for use in the healthcare sector. Jafco has invested in robotics before. Earlier this year, portfolio company Cyberdyne, a robot suit maker, raised $8