Top 50 Medical Device Startup Investors in Japan (August 2026)

Portfolio highlights

• ADiXi — Adixi is a tech-driven business that supports the idea that people and technology may work together. It strives to open doors by utilizing cutting-edge technology, such as artificial intelligence, to promote long-term, sustainable corporate and societal progress.
• WARPSPACE — ARPSPACE is a space startup originating from the University of Tsukuba, has been launching and working on a satellite development project at the University of Tsukuba for five years until the company was established.
• Luxna Biotech — Luxana Biotech is a biotechnology firm dedicated to promoting the practical use of safe and effective nucleic acid therapies. Utilizing nucleic acid chemistry technology, the company strives to provide nucleic acid medicines to patients suffering from diseases that currently lack effective treatments.

Portfolio highlights

• CastBio — Castbio specializes in antibody-drug conjugate-based drug discovery research and development. Along with medications, it also creates research reagents, medical equipment, in vitro diagnostic items, and offers drug discovery consulting.
• Eco-Pork — Eco-Pork is a co-creation solution farm that supports farmers' food productivity improvement. It is connecting the pig and technology, pork ( Pork ) new business ecosystems ( Ecosystem By building a), in the pork growing demand around the world, to get the most out of the food supply capacity is finite.
• IGrid Solutions — IGrid Solutions will promote “eDCM” to optimize power energy demand.

Portfolio highlights

• ADiXi — Adixi is a tech-driven business that supports the idea that people and technology may work together. It strives to open doors by utilizing cutting-edge technology, such as artificial intelligence, to promote long-term, sustainable corporate and societal progress.
• Alxtal — Alxtal is a tech company who optimize the development, design, and manufacturing processes of the manufacturing industry with IT and AI.
• Yokohama Vanilla — Yokohama Vanilla is a Company which operates Yokohama-based gift sweets brand.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Storm Therapeutics — Targeting pathways that modify RNA to deliver novel cancer therapeutics.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.
• Starlight Engine — Starlight Engine develops and commercializes fusion energy power plant technologies.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• Space BD — Space BD aims to become a one-stop shop to respond to all issues related to industrialization of space, and alleviate the work of businesses that are developing new technologies.
• KUZEN — KUZEN provides enterprise-grade chatbot technologies, especially the bot framework and NLP, via a visual UI without coding. The company is utilizing technology to develop a system that broadens the scope of dialogue. They use technology to provide their customers with next-generation standard procedures that broaden the possibilities ofconversation, resulting in unprecedented business practices.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• CaTe — CaTe is based in Tokyo. CaTe develops and manufactures a Digital Therapeutic (DTx) for remote cardiac rehabilitation. Their invention allows heart disease patients to safely and successfully complete cardiac rehabilitation utilizing standing exercise in a confined space, such as at home, without the use of ergometers or similar instruments.
• bestat — bestat is a developer of platforms for 3D data creation, management, and utilization using AI and offers digital twins services.
• FunPep — FunPep is an Industry-university collaboration bioventure company.

Portfolio highlights

• LQUOM — QWAVE offers cryptography communication technology.
• Alxtal — Alxtal is a tech company who optimize the development, design, and manufacturing processes of the manufacturing industry with IT and AI.
• Direava — Direava is a medical device company that manufactures, sells, leases, and maintains medical equipments along with consulting services.

Portfolio highlights

• Welyco — Welyco is an information technology company.We operate smart restaurant "solto". Utilize IT to realize efficient and diverse restaurant management.
• Toranotec — TORANOTEC CORPORATION aims to create a world where investment is familiar to everyone by realizing "from consumption to investment" through the services of asset management subsidiaries , utilizing advanced technology.
• Zeal Boxing Fitness — Zeal Boxing Fitness combines power of sports with the power of technology to provide a service that allows to enjoy fitness.

Portfolio highlights

• MW — MW is a smart home solution company that develops smart residential physical AI, robotics, and home design services.
• InsightX — InsightX is a technology platform focused on empowering businesses by simplifying complex processes and enabling smarter, more personalized user experiences.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
• TXP Medical — TXP Medical build a next-generation medical system through acute care.
• Startbahn — Startbahn aims to realize a richer society by providing the technology needed by artists and people involved with art all over the world. We are developing Startbahn Cert., a service that issues blockchain certificates for artworks, and promoting the development of Startrail, a blockchain infrastructure that is the basis for Startbahn Cert. We alsorun joint projects with other companies.

Portfolio highlights

• Any Style — Any Style develops a messaging app from voice actors that regularly sends messages via subscription. It also engages in the planning and production of audio content and the VTuber production business.
• Chaintope — Chaintope is specializes in blockchain technology with a focus for FinTech and non-FinTech sectors.
• Smile Robotics — Smile Robotics provides Service Robots in Japan.

Portfolio highlights

• A-Wave — A-Wave is a manufacturing company that develops and markets medical devices, pharmaceuticals, computer software, and hardware.
• Quali — Quali is dedicated to developing innovative products and solutions that support microsurgery, with the goal of addressing critical challenges in the medical field and improving patient outcomes and overall quality of life.
• Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• RoboTruck — RoboTruck develops autonomous driving technologies for huge trucks, as well as practical applications.
• Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

Portfolio highlights

• Varinos — Varinos is a clinical laboratory contract analysis company that is a partner of medical institutions. Varinos provides genomic testing development and contract analysis services using the latest technology, the next-generation sequencer.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .
• Equitas Medical Co. — Equitas Medical provides management support for clinics, including operational improvement, strategic planning, recruitment, digital transformation, and back-office administration. It supports business succession for clinic owners by providing transition options intended to maintain patient and staff continuity. The company also promotes healthcaredigital transformation through AI, cloud services, remote-care tools, hospital real-world data use, and medical department digitalization. Its services are intended for healthcare professionals, clinic owners, and healthcare organizations.

Portfolio highlights

• CMerTV — CMer TV is a platform that connects advertisers with newspapers, magazines, and specialized media by video
• Link Therapeutics — Link Therapeutics specializes in developing therapeutic methods for targeting autoantibodies and identifying pathogenic autoantibodies.
• Pixie Dust Technologies — Pixie Dust Technologies is a developer of computational technologies, including its ultrasonic phased array system with which one can generate force in mid-air; transport things in mid-air without touching anything; target and deliver different sounds from person to person in a crowd; direct guide-dogs; and even apply this in agricultural farming.

Portfolio highlights

• JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.
• LQUOM — QWAVE offers cryptography communication technology.
• Toregem BioPharma — Toregem BioPharma is a startup from Kyoto University that develops a treatment for congenital adentia. Toregem BioPharma is headquartered in Kyoto, Japan.

Portfolio highlights

• REVORN — REVORN is a fragrance AI and DX research and development company. They develop products such as odor sensors that can respond to odor issues and needs. They provide consultation at a range of levels, from identifying issues to developing solutions.
• Helical Fusion — Helical Fusion is a startup company that aims to commercialize fusion energy using magnetic confinement of high-temperature plasmas. It is a spin-off startup from the National Institute for Fusion Science (NIFS) in Japan that provides a fusion reactor based on the stellarator design, a magnetic confinement approach that enables inherently stable,continuous plasma operation.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• Triorb — The corporate website of TriOrb Inc., revolutionizing production lines with our ball-driven omnidirectional mobility platform.
• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
• Solaris — Solaris commercializes, manufactures, and sells soft robotics using pneumatic artificial muscles. Solaris was founded in 2017 and was headquartered in Tokyo, Japan.

Portfolio highlights

• Ripcord — Ripcord turns documents into powerful data. As a disruptor in the document intelligence market, Ripcord’s AI-driven platform harnesses proprietary robotics, generative AI, and cloud software to digitize and accurately derive vital information from paper and digital documents. Founded out of NASA research, Ripcord is backed by leading investorsincluding Kleiner Perkins, Google Ventures, Icon Ventures, Lux Capital, MUIP, and Apple co-founder Steve Wozniak.
• Rapidus — Rapidus is an Electronic component research, development, design, production, and sales that includes semiconductor elements and integrated circuits. Environmentally friendly, energy-saving semiconductors and semiconductor manufacturing technology are being researched and developed. Human resource development and training for the semiconductorsector.
• VALANX Biotech — VALANX Biotech is a site-specific protein conjugation platform to enable fast and cost efficient protein-drug-conjugates development.

Portfolio highlights

• BiPSEE — BiPSEE is a medical XR company that provides treatment support for children for the purpose of nurturing a sense of self-efficacy. They also deploy AR and VR animation with one button dentistry and medicine, whether outpatient or hospitalized in various situations your child's anxiety and pain relieve. It aims to reduce anxiety and pain inchildren in a wide range of medical fields such as dentistry, pediatrics, and dermatology.BiPSEE is abs ed in Tokyo, Japan.
• SEQUENTIAL — 5,971 Followers, 1,054 Following, 268 Posts - See Instagram photos and videos from Sequential Skin (@sequential.skin)
• ALT Sports Data — Real Time Alternative Sports Betting Data.

Portfolio highlights

• Molmir — Molmir is a biotech company that conducts research and develops treatments for intractable diseases based on sensing technology.
• EUV Photon — EUV Photon is an irradiation services company that conducts processing, evaluation, and measurement of materials for EUV lights.
• Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.

Portfolio highlights

• CELLORB — CELLORB provides player management, sports event planning, and event management services.
• L&F — L&F is a real estate company that develops rental portals and tools for vacant houses, family trusts, and rental property management.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• FerroptoCure — FerroptoCure is a research firm that specializes in ferroptosis research and the development of therapeutic drugs to treat diseases.
• Global Vascular — Global Vascular is an deep-tech firm focused on creating a stent designed to minimize foreign body reactions, utilizing a technological platform developed through a collaboration between medical and engineering experts. The company seeks to achieve early pharmaceutical approval to facilitate the restoration of blood circulation in the legs ofpatients suffering from peripheral arterial disease, who experience walking difficulties and need prompt intervention.
• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• KanonCure — KanonCure is a research and development company that engages in the discovery and development of regenerative medicine products and pharmaceuticals for liver diseases. The company conducts research in cell therapy and related therapeutic approaches for the treatment, diagnosis, and prevention of severe liver disorders. Its work includes methodsintended to reduce fibrosis associated with cirrhosis and support liver tissue regeneration.
• GAIA BioMedicine — GAIA BioMedicine is Based on the intellectual property and technology.
• Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• AstroX — AstroX is a private space startup company that develops satellite launch vehicles for space development. It utilizes the rockoon method for developing launch vehicles and small rockets to help clients easily use space.
• Sonire Therapeutics — SONIRE Therapeutics Inc. (SONIRE) is working on a next-generation high-intensity focused ultrasound (HIFU) therapy system that will employ acoustic engineering (ultrasound) technologies developed through cutting-edge academic research. SONIRE has been working on a next-generation high-intensity focused ultrasound (HIFU) treatment system as a noveltherapeutic modality with the goal of giving cancer patients and their families a new future.

Portfolio highlights

• LQUOM — QWAVE offers cryptography communication technology.
• FullDepth — FullDepth is a company that creates marine drones to aid with underwater monitoring. The company's drones work in tandem with marine navigation technology, which monitors and captures aquatic life, communicates data to connected devices, and provides infiltration information that can be freely used with a cloud service, allowing customers towitness and study marine life for educational and recreational purposes.FullDepth is a company that creates marine drones to aid with underwater monitoring. The company's drones work in tandem with marine navigation technology, which monitors and captures aquatic life, communicates data to connected devices, and provides infiltration information that can be freely used with a cloud service, allowing customers to witness and study marine life for educational and recreational purposes.
• Physiologas Technologies — Physiologas Technologies is a manufacturing company that designs and develops medical equipment for the healthcare industry.

Portfolio highlights

• Yondemy — Yondemy is an online platform for children reading books.
• Yokohama Vanilla — Yokohama Vanilla is a Company which operates Yokohama-based gift sweets brand.
• Zeal Boxing Fitness — Zeal Boxing Fitness combines power of sports with the power of technology to provide a service that allows to enjoy fitness.

Portfolio highlights

• ASEMtech — ASEMtech is a technology company that specializes in research, development, sales, and leasing of medical equipment via the ASEM method.

Portfolio highlights

• AlgaleX — AlgaleX is a food technology and biotechnology company that develops AI-powered algae fermentation technology to produce sustainable food ingredients, nutritional compounds, and bioproducts. The company leverages proprietary AI-driven cultivation and fermentation systems to convert underutilized food byproducts into high-value microalgae rich innutrients such as DHA, umami compounds, and other functional ingredients. Its mission is to build a circular bioeconomy by reducing food waste while providing sustainable alternatives to marine- and animal-derived ingredients.The company's core technology is Touji-24, an AI-powered algae cultivation and fermentation control system that automates and optimizes microalgae production. Using proprietary fermentation processes and food byproducts such as awamori lees, AlgaleX cultivates algae that can be used to produce Umamo, a plant-based ingredient combining seafood-like umami flavor with high concentrations of DHA. This approach reduces reliance on wild-caught fish as a source of omega-3 fatty acids while upcycling food industry byproducts into valuable nutritional ingredients.
• Solafune — Solafune integrates multi-domain intelligence across space, cyber, and physical layers to create actionable, sovereign decision systems.
• Mign — Mign offers a generative AI-related SaaS solutions for the construction and real estate fields.

Portfolio highlights

• Molmir — Molmir is a biotech company that conducts research and develops treatments for intractable diseases based on sensing technology.
• ASEMtech — ASEMtech is a technology company that specializes in research, development, sales, and leasing of medical equipment via the ASEM method.
• Greenase — greenase is a manufacturer and seller of processed agricultural products.

Portfolio highlights

• Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
• Serendip Consulting — Serendip Consulting refers to business portfolio optimization and provision of effective solutions.The Serendip Group operates not only strategic and financial consulting, but also a business company with a focus on manufacturing. Aiming for further growth of the entire group by restructuring the "business portfolio" based on the know-howof nurturing small and medium-sized businesses cultivated over 10 years since its foundation and investment experience, and "modernizing management" by dispatching professional managers You.
• Monozukuri Business Succession Holdings (JMS) — Monozukuri Business Succession Holdings is a specialized corporate investment subsidiary. The platform modernizes mid-sized manufacturing firms facing generational leadership transitions. Strategic institutional banking partnerships protect public shareholder equity from dilution. After acquisition, the firm installs professional management andautomated factory systems. All operational yields consolidate into the parent organization to drive long-term growth.

Portfolio highlights

• Deja — Modern Rituals & Natural Products from the Ancient Science of Ayurveda
• Enoki Inc — Multiplayer-enabled tools for developers. Enoki has 18 repositories available. Follow their code on GitHub.
• Homethings — Single-use plastic is bonkers. Homethings makes cleaning products that make sense. No more shipping water in plastic bottles. We send non toxic cleaning tabs so that you can refill over and over again using your tap.

Portfolio highlights

• Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
• Black Cat Carnival — Black Cat Carnival Inc. is a communication service development company.
• Carbon CryoCapture — Carbon CryoCapture specializes in the carbon dioxide separation systems aimed at creating economically viable, energy-efficient, and genuinely sustainable CO2 separation and recovery technologies. The company is dedicated to deploying cost-effective, efficient systems for CO2 capture that integrate smoothly with current infrastructures, all whileenhancing energy consumption and production. This enables clients to attain zero emissions throughout the development and application of resources.

Portfolio highlights

• JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.
• Cosomil — Cosomil develops early diagnostic drugs for diseases and provides research and development support to healthcare companies.
• Physiologas Technologies — Physiologas Technologies is a manufacturing company that designs and develops medical equipment for the healthcare industry.

Portfolio highlights

• Luxonus — Luxonus is a product development of a new imaging device using optical ultrasonic technology.
• Meltin MMI — Meltin MMI is a cyborg-technology company that focuses on biosensors and robotic arms. Meltin has successfully enabled fine finger movements, such as for amputees and participated in Cybathlon 2016 and won the Microsoft Innovation Award.
• Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.

Portfolio highlights

• Listie — Listie is an industrial engineering company that develops, supplies, and maintains lithium separation equipment and membranes. It is an important infrastructure resource that supports modern life, including electric vehicles, smartphones, and renewable energy storage.
• Dioseve — Dioseve is providing novel possibilities for all life.
• BEAM Technologies — BEAM Technologies, focuses on developing optical semiconductor devices using special light to offer clean solutions to ecosystem-related problems.

Portfolio highlights

• SecureNavi — SecureNavi offers automation tools for the information security management system. It reduces conventional analogue operations using excel and word. For inquiries, telephone numbers and physical addresses are available on their website.
• Kokoro Mill — Kokoro Mill is a manufacturing company that designs medical devices to analyze autonomic nervous system activity and arrhythmias.
• NEXTAGE — Nextage is an Agri-tech company that offers wasabi cultivation in a container.

Portfolio highlights

• MOVeLOT — MOVeLOT is an AI company that provides skeletal platform and robot planning, development, and production services.
• Kisui Tech — Kisui Tech is an agricultural AI robotics company that help farmers for farming.
• LYMPHOGENiX — LYMPHOGENiX is the pioneer company for lymphatic vessels regeneration. Our proprietary technology revitalizes the function of lymphatic vessels, making us experts in treating various health conditions. Our treatment is also great for skin-aging, obesity, Alzheimer's diseases and infertility. We believe in helping our clients improve their vitality and energy, one treatment at a time.

Portfolio highlights

• Unocoin — Unocoin a cryptocurrency exchange in India, offers seamless trading of Bitcoin & other cryptos. With 2M users Since 2013. Join India's trusted crypto platform.
• Kava Labs — Kava is a lightning-fast Layer-1 blockchain that combines the two most used permissionless execution environments into a single, scalable, developer-optimized network.
• Triple W Japan — Triple W develops DFree, the first wearable device for incontinence that can track the progression of bladder movements using a non-invasive ultrasonic sensor. The device will help elderly and disabled people who suffer from incontinence by notifying when they will need to go to the bathroom. DFree is now widely marketed in Asia and Europe and usedin over 500 senior care facilities. Triple W has offices in Japan, France, and the US.

Portfolio highlights

• Ubitus — As cloud gaming enablers, Ubitus' GPU virtualization, Streaming technology and hybrid cloud deployment can serve different kinds of solutions for Telco, Game companies to quick enter cloud gaming market. Moreover, Ubitus provide Global distribution and New Media content solution for new media studio and fashion brand to help them distribute rich media contents worldwide.
• POPS Worldwide — POPS Worldwide is the leading digital entertainment company in Southeast Asia. With over 4 billion monthly views of its music and entertainment content, POPS is the fastest growing digital entertainment media company with hundreds of artists, content creators and partners from broadcast television, publishing and production in the POPS Network.POPS also produces a wide variety of original content for its industry-leading owned and operated channels like POPS Music, POPS Kids, POPS TV, Beauty Me, HerVoice and CoolTV that target highly sought after demographics: teens, kids, women and men.
• Global Equipment Services — As a strategic partner to developers of multi-sector products, Averna provides innovative automated testing tool and quality assurance solutions.

Portfolio highlights

• Neubond — Neubond develops wearable devices for stroke mobility rehabilitation. These devices provide autonomous assistance and therapy during daily activities, integrating rehabilitation into the patient's daily life regardless of their motor capabilities. Neubond's solutions are designed to be intuitive and effective, aiming to improve thequality of life for individuals undergoing rehabilitation.
• Pestalozzi Technology — Pestalozzi Technology is a development and provision of educational products in the fields of physical education and club activities.
• Gel-Coat Biomaterials — Gel-Coat Biomaterials is a biotechnology company that develops innovative bio-based materials and new medical technologies.

Portfolio highlights

• LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
• Metcela — Cells hold endless possibilities. Through science, we will unlock these potentials and harness them to improve the lives of patients worldwide.
• Hirosaki Lifescience Innovation — Hirosaki Lifescience Innovation is engaged in the development, manufacture, and sale of regenerative medicine products.

Portfolio highlights

• F.MED — F.MED is a manufacturing company that designs and develops robotic microsurgical devices for the healthcare industry.
• Peco Free — Peco Free is a school meal pre-order service that is selected using a smartphone.
• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.

Portfolio highlights

• ULUU — ULUU is an ocean material that replaces plastic and actively benefits the world.
• Aquaria — Aquaria provides solutions to secure access to clean water. The organization adapts its approaches based on the needs of these communities. It addresses water-related challenges through various methods.
• Funderbeam — Funderbeam is a funding and trading platform that connects companies and investors to buy and sell equity stakes. The platform allows the founders to gain exposure, legal support, a funding manager, or an investor network. It also allows the investors to take control of their investments and trade anytime they want.The company was founded in 2013as a global data platform for startup companies.

Portfolio highlights

• Kakutoku — Nitlon Inc. provides crowdsourcing management services. The company was founded by Seiya Mitsuda on February 02, and is headquartered in Beppu, Japan.
• AlarmBox — AlarmBox develops services that make use of professional knowledge of technology and corporate screening, and changes common sense of risk management of enterprise.
• NexusAdvisors — NexusAdvisors operates AvaCareer, an AI-powered recruitment platform that leverages intelligent AI agents to support both companies and job seekers by streamlining hiring processes, enhancing candidate matching, and improving recruitment efficiency.

Portfolio highlights

• 3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
• THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
• Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.

Portfolio highlights

• Sinumy — Sinumy develops touchless identity authentication technology and high-speed, high-precision position measurement technology.
• xCARE — xCARE specializes in the development and commercialization phases of the pharmaceutical and medical device industries.
• Yellow Blue — Yellow Blue develops and operates "Blue One," a next-generation AI translation service designed for professionals.

Portfolio highlights

• CaTe — CaTe is based in Tokyo. CaTe develops and manufactures a Digital Therapeutic (DTx) for remote cardiac rehabilitation. Their invention allows heart disease patients to safely and successfully complete cardiac rehabilitation utilizing standing exercise in a confined space, such as at home, without the use of ergometers or similar instruments.
• OOYOO — OOYOO Co., Ltd. is a DeepTech venture that combines international entrepreneurial spirit, and a 'Made In Japan' excellence, to bring the latest innovations in clean technology to society for a smarter, cleaner, and more mobile world.
• KG Motors — KG Motors is an automotive firm that manufactures electric vehicles that can be moved comfortably and safely by one person.

Portfolio highlights

• LQUOM — QWAVE offers cryptography communication technology.
• Atom — Atom is a humanoid robot built platform. Its bipedal, dual-armed robots are designed not just as industrial tools but as collaborators that expand human capability. By combining advanced Physical AI—environmental perception, judgment, and action planning—with robust robotic hardware, Atom is creating adaptive agents capable of working acrossdiverse settings to augment or, where appropriate, replace human labor. The company positions these robots as a next step in societal evolution: a new class of machines that learn and behave in human-like ways to advance productivity, safety, and quality of life.
• Link Therapeutics — Link Therapeutics specializes in developing therapeutic methods for targeting autoantibodies and identifying pathogenic autoantibodies.