Top 50 Manufacturing Startup Investors in Japan (June 2026)

Portfolio highlights

• Diggle — DIGGLE is a service that provides fundamental management accounting management on the cloud called fraud management. It is possible to reduce the mistakes and man-hours of the fraud management task and easily carry out the fraud management task even if it is not an expert in finance or accounting.DIGGLE covers budget creation work and budgetrecord comparison work, especially in the foreman management work. In the budget creation work, the KPI and the budget are automatically created by inputting the target numerical value to the preset parameters utilizing the budget generator function, while the forecast contrasting work is made up of the financial information, non-financial information It is easy to calculate by simply entering the numerical value, and it is possible to carry out calculation of the forecast contrast.
• Fermelanta — Fermelanta produces rare plant-based ingredients through microbial fermentation. It engineers a cell to build a biosynthetic pathway of target molecules with gene transfer and disruption.
• Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.

Portfolio highlights

• Letara — Letara operates a space technology platform with the intention to serve a logistics network covering the solar system. The company produces hybrid propulsion engines for small spacecraft, promoting groundbreaking advances in space propulsion with high thrust, safe, and inexpensive propulsion system technology.
• Pragtech — Pragtech develops and operates parking lot service software that helps to eliminate payment congestion and reduce operating costs.
• Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.

Portfolio highlights

• CastBio — Castbio specializes in antibody-drug conjugate-based drug discovery research and development. Along with medications, it also creates research reagents, medical equipment, in vitro diagnostic items, and offers drug discovery consulting.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.
• Reborna Biosciences — Reborna Biosciences provides research and development in the field of genetic diseases. The company develops therapeutic options for area of unmet medical needs in genetic rare disease. The company's technology enables low-molecular compounds to target ribonucleic acid. The company provides new disease-modifying drugs for patients sufferingfrom rare genetic diseases including spinal muscular atrophy.

Portfolio highlights

• Paytner — yup is providing services to support freelance people's funding.The freelance population in Japan has been shown to continue to increase in many Chosa. While working styles are diversified, they are not able to respond to the development of the working environment, and they will develop their business to change the situation where problemssuch as funding, credit, sexual harassment, and power harassment are accumulated.
• Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
• Black Cat Carnival — Black Cat Carnival Inc. is a communication service development company.

Portfolio highlights

• Josys — Stop letting runaway SaaS costs & unsecured SaaS access ruin your day. Josys is the only SaaS Management Platform that provides true 360-degree control.
• YouAppi — Change the way the game is played and make a lasting impression, the second time around. YouAppi mobile advertising puts your app where you want it — top of mind. Find new users and reactivate lapsed users to grow your app revenue with YouAppi. Follow us on Twitter, Facebook or LinkedIn, or for more information, visit www.youappi.com.
• Zenno Astronautics — Zenno Astronautics hardware and software products ensure satellite missions are effectively managed, guaranteeing maximum economic returns and responsible use of space.

Portfolio highlights

• Logiless — Logiless is a cloud type all-in-one software dedicated to net shop. Since both orders and stocks can be managed together in a logical manner, efficiency of operations can be realized at low cost.
• LUC — LUC is a provider of the AI ​​x experience analysis platform "TERUS," .
• Turing — Turing develops and manufactures fully autonomous vehicles.

Portfolio highlights

• Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
• Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
• MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.

Portfolio highlights

• MOVeLOT — MOVeLOT is an AI company that provides skeletal platform and robot planning, development, and production services.
• Chaintope — Chaintope is specializes in blockchain technology with a focus for FinTech and non-FinTech sectors.
• xCARE — xCARE specializes in the development and commercialization phases of the pharmaceutical and medical device industries.

Portfolio highlights

• F.MED — F.MED is a manufacturing company that designs and develops robotic microsurgical devices for the healthcare industry.
• Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .

Portfolio highlights

• OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
• Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.

Portfolio highlights

• Piazza — PIAZZA deploy the regional platform PIAZZA.
• FullDepth — FullDepth is a drone development company.
• Gaudi Clinical — Gaudi Clinical is a health care firm that engages in regenerative medicine outsourcing and cell processing contract establishments.

Portfolio highlights

• Yadokari — Yadokari provides various types of Construction & Real Estate related other services.
• FullDepth — FullDepth is a drone development company.
• Peco Free — Peco Free is a school meal pre-order service that is selected using a smartphone.

Portfolio highlights

• Plott — Plott producing youtube animation platform under Vision “Become a Content holder from YouTube”. In August 2019, the company name was changed from Fabo to Plott. Plott, the new company name, is derived from the plot that you make before writing novels, etc., and the idea that “I want to make content all the time” is put in the company name.
• Sharing Energy — Sharing Energy is providing energy supply and energy management services.
• The Chain Museum — The Chain Museum creates a platform for connecting individuals .

Portfolio highlights

• Menou — MENOU specializes in AI technology and sensing technology. It features a graphical image identification modeler software.
• Castee — Castee provides social collaboration services and also helps with a tool for job requests and overseas projects for creators.
• 3S — 3S is a SaaS developer platform that provides and operates 24-hour home nursing care services through technology.

Portfolio highlights

• Autify — AI software testing company aimed at solving the challenges associated with automation testing. We are passionate about making software testing faster and easier, empowering companies to release faster and keep their applications stable.
• Nekonome — Nekonome creates a game platform with global character designs, in-game updates, and regular events, providing a personalized gaming experience based on data.
• AVA Intelligence — AVA Intelligence is a Internet service development company.

Portfolio highlights

• Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.
• Japan Wind Tunnel Manufacturing — JAPAN FUDO is a company that develops and manufactures new products related to wind, such as the world's most compact wind tunnel "Aero Optim" series and double propeller wind turbines.
• RICOS — RICOS is a tech company that optimizes manufacturing processes using AI, simulation, and high-performance computing technologies.

Portfolio highlights

• Linqmed — Linqmed is a pharmaceutical company that specializes in the research and development of radiopharmaceuticals for cancer treatment.
• Simple Form — Simple Form provides real-time information on all domestic corporations necessary for financial institutions. We will accelerate the time-consuming and labor-intensive research work of corporations and take on the role of new financial underpinnings.
• Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.

Portfolio highlights

• QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
• Luxna Biotech — Luxana Biotech is established to contribute to medical treatment for suffering patients, .
• Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.

Portfolio highlights

• ElleThermo — elleThermo aims to implement Semiconductor-Sensitised Thermal Cells (STCs), an energy conversion technology that can generate electricity from unused waste heat above room temperature.
• Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• QibiTech — QibiTech created HATS, a service in which a human operator remotely supplements the operation of a robot. Add-on edge calculator or software for various robots to increase robot flexibility. It also serves as a platform for connecting operation data to the business improvement system.
• SPACECOOL — Spacecool offers zero-energy cooling materials that radiate heat to space, reducing temperatures and mitigating global warming.
• Turing — Turing develops and manufactures fully autonomous vehicles.

Portfolio highlights

• LQUOM — QWAVE offers cryptography communication technology.
• Captain Fresh — Captain Fresh is a freshwater fish and seafood supply chain platform. Captain Fresh is a B2B marketplace leveraging technology to deliver the fastest harvest-to-retail in the industry. The company focuses on aggregating the fragmented retail demand across the country and linking them to the small fishermen and farmers throughout the Indian coast.The company was founded in 2019 and is based in Bengaluru, India.
• Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.

Portfolio highlights

• Nexta — Nexta manufactures site, issues such as analog management, personalization of operations & labor shortages are becoming more serious.
• Logo Labo — Logo Labo provides branding and marketing services, including brand development, formulation, IT-based branding and marketing support.
• MUSE — MUSE is a robotics company that provides robotic solutions for retail stores to support in-store operations.

Portfolio highlights

• Ababa — Ababa provides recruitment and employment solutions.
• PlaceHolder — Placeholder is a space value creation company that provides people with inspiring and exciting experiences by fusing digital technology and real space.
• RICOS — RICOS is a tech company that optimizes manufacturing processes using AI, simulation, and high-performance computing technologies.

Portfolio highlights

• ImmunoScape — ImmuniScape discovers and develops novel TCR-based therapeutics against solid tumors
• Metcela — Cells hold endless possibilities. Through science, we will unlock these potentials and harness them to improve the lives of patients worldwide.
• Startbahn — Startbahn develops Startrail, a sustainable and scalable blockchain infrastructure that assures the reliability, authenticity, and traceability of artworks.

Portfolio highlights

• Cloudian — Cloudian provides exabyte-scale storage for your capacity-intensive workloads: S3-compatible storage for on-prem, hybrid cloud, and multi-cloud.
• Seajacks — Cadeler is a global leader in offshore wind farm construction, maintenance, and decommissioning.
• Vehicle Energy Japan — Vehicle Energy Japan specializes in development, manufacturing and sales of automotive lithium-ion batteries.

Portfolio highlights

• KG Motors — KG Motors is an automotive firm that manufactures electric vehicles that can be moved comfortably and safely by one person.
• Lx Design — Lx Design is an application that connects schools with people who wants to work as a teacher.
• ForestFolks — ForestFolks Provider of forest management and conservation services aimed at protecting forestry and the environment.The company exploits and successfully employs the forest's CO2 absorption potential and conserves and recovers forest resources and biodiversity, allowing for regulatory compliance and supporting environmental protection.

Portfolio highlights

• Koeda — KOEDA is researching and developing medical devices that are safe, painless, and easy to use for acute cholecystitis. KOEDA will transform the management of cholecystitis. So far, endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) has been a notably difficult procedure carried out by skilled doctors at specific advanced centers. Althoughinserting a tube into the gallbladder is less invasive, it is complex, and there may be concerns regarding bile leakage. By combining clinical expertise with precision engineering, KOEDA addresses a clearly defined medical need in a growing global market and is currently moving forward on schedule for regulatory clearance and commercialization.
• AI Silk — AI Silk are innovative conductive fibers produced with a dyeing technique. By using natural silk and giving conductivity to the fiber itself, They have succeeded in producing electrodes that reduce some of the risks and challenges of conventional medical electrodes, which can cause discomfort,skin and in vivo inflammation, and measurement failuredue to sweat or other elements. Their brand, AI Silk, is a new material that has strong and diverse application potential, even beyond the health / medical field.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• CELLORB — CELLORB provides player management, sports event planning, and event management services.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• CuboRex — CuboRex realizes creative mobility using its crawler technology.
• RemitAid — RemitAid is a fintech company that operates an overseas payment platform for cross-border transactions between companies.
• FiberCraze — FiberCraze is a manufacturing company that specializes in the development and sales of thread materials.

Portfolio highlights

• Aracan — Aracan is an e-commerce business that provides online and offline car-sharing services for vehicles.
• Biophilia — Biophilia is a company specializing in pet-related, consulting business, internet service business, and consignment development business. The company was established in August 2017 and is based in Shibuya-ku, Tokyo, Japan.
• Pacific Meta — Pacific Meta is a tech startup that creates a web3 platform with the goal of offering guidance to businesses using blockchain technology. The firm platform aids in the product's localization for the Japanese market and offers community management services, enabling businesses to promote themselves on social media platforms and work withinfluencers in the cryptocurrency space.

Portfolio highlights

• Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.
• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
• Zip Infrastructure — Inquiry : https://docs.google.com/forms/d/e/1FAIpQLSfDmxd1TpPP331TY4VoRsvn0yWX3Ca5Jd-bfBiuPwvpD2SKtA/viewform

Portfolio highlights

• Josan-shes — Josan shes is web start up that offers nursing service to women and babies.
• ACCEL Stars — ACCEL Stars is a fitness and wellness firm that offers sleep diagnosis and examinations like sleep health, hygiene and medical devices.
• Cellid — Cellid developing the waveguide-architecture display module for AR glasses and high-performance spatial recognition software.

Portfolio highlights

• KG Motors — KG Motors is an automotive firm that manufactures electric vehicles that can be moved comfortably and safely by one person.
• SoVa — SoVa operates an accounting firm that combines technology and experts.
• Pixie Dust Technologies — Pixie Dust Technologies is a developer of computational technologies, including its ultrasonic phased array system with which one can generate force in mid-air; transport things in mid-air without touching anything; target and deliver different sounds from person to person in a crowd; direct guide-dogs; and even apply this in agricultural farming.

Portfolio highlights

• Gecipe — Gecipe is a video service for e-sports players.
• Issues — Issues provides development and management of web service issues that solve the problems.
• SecureNavi — SecureNavi offers automation tools for the information security management system. It reduces conventional analogue operations using excel and word. For inquiries, telephone numbers and physical addresses are available on their website.

Portfolio highlights

• CUSTA —
• YOUTRUST — YOUTRUST is a startup to operate YOUTRUST a referral recruitment platform for side-job change.
• Josh Collaboration — Josh Collaboration is a software company that provides mailing, fax transmission, and partner management services.

Portfolio highlights

• KOMPEITO — Office de Yasai is an online platform that enables users to order and get vegetables delivered to their offices. The platform’s operations are based in Tokyo, Japan.
• Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.
• Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• RoboTruck — RoboTruck develops autonomous driving technologies for huge trucks, as well as practical applications.
• Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

Portfolio highlights

• Nstock — Nstock is specialized in developing SAAS based applications for ecosystem.
• STRACT — STRACT is a web platform that provides online platform, dating app, knowledge sharing cloud platform, and casual entertainment services.
• PartnerSuccess — PartnerSuccess develops and provides SaaS tools that automate the collaboration between manufacturers and distributors.

Portfolio highlights

• Nyriad — Nyriad is developing the industry's first storage solutions based on a new architecture that redefines how data is stored. The architecture combines the power of GPUs and CPUs to deliver an unprecedented combination of performance, resilience, and efficiency, enabling massive amounts of data and multiple data types to be managed in a singlestorage system that is simple to deploy, operate, scale, and maintain. Headquartered in Austin, Texas, Nyriad is building a new storage architecture from the ground up that empowers businesses to grow, adapt, and stay competitive in a data-driven world. For more information, visit us on the web at www.nyriad.io.
• Astra Food Plan — Astra Food Plan is a manufacturer and supplier of superheated steamer, food processing equipment and food powders.
• Aero Development Japan — Aero Development Japan develops drone engine for the transportation industry. It was established to develop only one hybrid engine for large and long-distance drones in the world. Vision aims to contribute to the development of the world by developing a hybrid engine suitable for drones with less electrical control and providing it as a powersource for weight and long-distance drones. The company's distinctive feature is that it does not embrace all of its technological processes, and integration of these excellent technologies to develop hybrid engines for large and long-distance drones from Japan.

Portfolio highlights

• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
• VLP Therapeutics — VLP Therapeutics, LLC (VLP) was established in 2012 by seasoned biopharmaceutical veterans with mission to develop innovative medical treatment which transforms traditional vaccine and targeted antibody therapies to address global unmet medical needs. Its vision is to combat the 21st century global public health problems through revolutionary nextgeneration i-αVLP (inserted alpha VLP) Technology. The company is headquartered in Gaithersburg, Maryland
• XFOREST Therapeutics — xFOREST Therapeutics develops a drug discovery platform that targets RNA structures.

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• Robofull — Robofull is a manufacturing firm that specializes in the design and sale of automation equipment for factories to solve the labor shortage.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• ACCIONA — At ACCIONA we offer sustainable solutions to the most urgent challenges facing the planet, such as global warming, energy needs and water shortages
• Kyoto Fusioneering — Kyoto Fusioneering is a research & development, design, and manufacture of parts related to fusion reactors.
• Hunter Point Capital — Hunter Point Capital is an independent investment firm seeking to provide innovative capital solutions to alternative asset managers across the globe.

Portfolio highlights

• Lisse — Lisse offers legal business innovation through the use of AI.
• FastLabel — FastLabel's mission is to become an infrastructure that solves the problems and accelerate the practical application of AI.
• Jeplan — JEPLAN Creates New Recycling Infrastructures & Managements For the Future of Our Planet.

Portfolio highlights

• MoonJapan — MoonJapan is an educational impact startup that offers a variety of programs and thorough assistance.
• Respo — Respo is a service that enables people to save money by buying things at a discount.
• Prefab — Prefab offers cutting-edge AI SaaS solutions tailored for the construction industry, enhancing efficiency, safety, and decision-making through data-driven insights.

Portfolio highlights

• PXP — PXP is a green tech development firm that develops clean energy using next-generation photoelectric conversion elements.
• SPACECOOL — Spacecool offers zero-energy cooling materials that radiate heat to space, reducing temperatures and mitigating global warming.
• Clean Energy Connect — Clean Energy Connect is into offering green energy solutions. It invests in its own generation capacity for a stable electricity supply by not harming nature.

Portfolio highlights

• TBM — TBM is a company that develops, manufactures and sells paper and plastic alternative products made from a limestone-based material known as “LIMEX”.
• FIREBUG — FIREBUG enables comedians, actresses, models, artists, managers, and creators to develop their skills. They arrange production plans for numerous talents and create IP and advertising items based on the social networking sites of the talents. Additionally, they offer marketing solutions built around a range of talent-focused content. They offerbasic marketing assistance and advertising for businesses.
• IDN Media — IDN Media is the leading media platform company for Millennials and Gen Z in Indonesia.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Scimplify — Scimplify delivers innovative specialty chemical solutions as a trusted manufacturer and global supplier to industries including pharma, food, and cosmetics
• EF Polymer — EF Polymer Private Limited providing 100% Organic and fully Biodegradable Super Absorbent Polymer cum Fertilizer to reduce Water and Fertilizer requirement for your plant. Let's grow organically.
• iMicrobes — We are a synthetic biology company on the mission to work with the world's largest companies to use new raw materials and recycle waste for chemical production, polymers, agriculture, and space exploration.

Portfolio highlights

• Univearth — Univearth is a tech company that specializes in developing a logistics digital transformation platform to modernize the logistics industry.
• Stack — Stack is the developer and provider of the SaaS-based retail mission-critical system.
• Umee Technologies — Umee Technologies is an IT firm that offers full-stack development, conversational AI, and psychological analysis engine services.

Portfolio highlights

• Sabu — Sabu is an online work agency that offers back-office operations, web production, and outsourcing services for the dental care industry.
• Vesicle — Vesicle is a fruit and vegetable company that provides distribution and delivery of fresh vegetables.
• CLEAR INNOVATION — CLEAR INNOVATION Co., Ltd. is a technology company with the mission to "Turn the unconventional into the new normal." This reflects a commitment to reshaping standards by addressing and solving potential problems previously deemed unsolvable, and by establishing new de facto infrastructure for society. The company positions itself at theforefront of innovation, consistently pursuing solutions that others have given up on and challenging norms to create lasting positive change.