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Top 50 Life Science Startup Investors in Japan in September 2025

Last updated: Sep 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Life science startups based in Japan. We rank investors based on the number of investments they made in Life science companies from Japan. We update this investor list every month.

Top 50 Life Science Startup Investors in Japan in September 2025

Investor	Life Science Japan investments
Mitsubishi UFJ Capital	4
Osaka University Venture Capital	4
Miyako Capital	4
UntroD Capital	4
Nissay Capital	4
JAFCO	3
SMBC Venture Capital	3
Keio Innovation Initiative	3
Senshu Ikeda Capital	3
Nippon Venture Capital	3
SBI Investment	3
Angel Bridge	2
Incubate Fund	2
ANRI	2
Mizuho Capital	2
Real Tech Japan	2
PALTEK	1
Sosei CVC	1
Japan Science and Technology Agency	1
Kaga Electronics	1
Sompo Holdings	1
Fast Track Initiative, Inc.	1
SPARX Group	1
Fuyo General Lease	1
Lifetime Ventures	1
WASEDA University Ventures	1
Innovation Engine	1
Mitsui Mining & Smelting	1
Hiroaki Kitano	1
DBJ Capital	1
Delight Ventures	1
Media Future	1
Will Capital Management	1
Mobile Internet Capital	1
FueTrek	1
Capital Medica Ventures	1
Mitsubishi Gas Chemical	1
ReBoost	1
HERO Impact Capital	1
Genesia Ventures	1
Energy & Environment Investment	1
Chuo Shinkin Venture Capital	1
Kyogin Lease & Capital	1
QB Capital	1
CareNet	1
Kenshin Fujiwara	1
Chushin Venture Capital	1
Japan Finance Corporation	1
Japan Material Technologies	1
Shoji Okamoto	1

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Investor list

Mitsubishi UFJ Capital is a venture capital firm focusing on life science, ICT, and high technology investments.

Investment focus

Information Technology, Software, Health Care
Funding Round, Series A, Series B
Japan, United States, Singapore

Portfolio highlights

LiLz — LiLz is an IT technology network for businesses looking to use AI and IoT to offer new services and value.
Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
FUNDiT — FUNDiT is an IT-focused M&A and business consolidation company that specializes in acquiring, managing, and scaling IT companies.

Osaka University Venture Capital is a venture capital firm that focuses on early-stage ventures in the fields of life innovation, green innovation, and platform technology. The firm was founded in 2014 and based in Osaka, Japan.

Investment focus

Biotechnology, Manufacturing, Health Care
Funding Round, Seed, Series A
Japan

Portfolio highlights

Ayumo — Ayumo is a research and development company that provides deep learning services with medical insights and AI technology.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
EX-Fusion — EX-Fusion develops the first commercial laser based nuclear fusion reactor for power generation.

Miyako Capital is the venture capital that manages Kyoto University 2nd Venture Fund (KUVF). The company was founded in 2013 and based in Kyoto & Tokyo, Japan. Investment fields are: 1) Life Science, Biotechnology: Drug creation, regenerative medicine, medical beauty equipment, medical services.2) Agri-Food: Industrialization,agricultural and fishery products growth-promoting technology, specified health food, health food.3) Environment, Energy: Alternative energy, and related technologies.4) IT, Electronics: Web, mobile related devices and application, telecommunication technology, security, consumer and business oriented application, mechatronic, robot.5) New services utilizing state-of-art technology.Investment stages: Primary investment stages are initial-growth stages of seed and early. However, we aim at all growth stages and make investment in post-IPO portfolio companies as well as public companies that are related with Kyoto University.

Investment focus

Medical, Biotechnology, Information Technology
Series A, Seed, Series B
Japan, United States, United Kingdom

Portfolio highlights

Mui Lab — Mui is an aesthetically-pleasing wooden IoT device connected to a cloud service. By accessing information through natural wood, we can rethink a new type of lifestyle.
Fermelanta — Fermelanta produces rare plant-based ingredients through microbial fermentation. It engineers a cell to build a biosynthetic pathway of target molecules with gene transfer and disruption.
Oishii — Oishii Farm provides indoor vertical farming technology. Oishii sells via supermarkets, offering a container of between eight and 11 strawberries for $50 per package. Hiroki Koga and Brendan Somerville started the company in 2017.

UntroD Capital is an R&D-based innovative technology that specializes in social implementation.

Investment focus

Manufacturing, Biotechnology, Health Care
Funding Round, Seed, Series A
Japan, Singapore, Austria

Portfolio highlights

CyCraft — CyCraft secures national governments, Fortune 500 firms, and SMEs with our Japan Interop 2020 Best of Show and MITRE ATT&CK®-evaluated AI platform, CyCraft AIR, that delivers 1) endpoint detection & response, 2) network detection & response, 3) operational global threat intelligence and 4) enterprise cyber-health checks.
Innovacell — Innovacell is a biotechnology firm entirely focused on the area of tissue engineering and it operates one of Europe's largest and most modern production facilities for the proliferation of the body's own tissue cells. Its supervisory board is chaired by the experienced financial expert, Dr. Harald Pöttinger, a director of Alpine EquityManagement AG, based in Bregenz, Austria. Innovacell currently employs 20 staff as well as numerous outside experts.
Reborna Biosciences — Reborna Biosciences provides research and development in the field of genetic diseases. The company develops therapeutic options for area of unmet medical needs in genetic rare disease. The company's technology enables low-molecular compounds to target ribonucleic acid. The company provides new disease-modifying drugs for patients sufferingfrom rare genetic diseases including spinal muscular atrophy.

Nissay Capital is a venture capital Company specializing in seed, start-up, growth capital, middle stage, and later stage investment.

Investment focus

Health Care, Internet, Information Technology
Funding Round, Seed, Series A
Japan, United States, Ethiopia

Portfolio highlights

Japan AI — Japan AI specializes in R&D of artificial intelligence and consulting services.
Blackbox — Blackbox is an entertainment firm that is involved in businesses, including VTuber production, media mix, and live music events.
Linea Innovations — Linea Innovations is an energy production company that develops commercial fusion reactors with advanced fuel technology.

Since its founding in 1973, JAFCO has always worked with leading-edge entrepreneurs. The total capital commitments of its investment funds in Japan and overseas have exceeded 1 trillion yen and the number of portfolio IPOs to date has reached over 1,000. In addition to venture investment, JAFCO also carries out buyout investment and commit to thecreations of innovative technologies and services worldwide. As entrepreneurs’ closest partner in bringing their visions to life, JAFCO provides support in areas of HR, marketing/ sales, and back-office operations, in addition to providing financing.

Investment focus

Information Technology, Software, Artificial Intelligence
Series A, Funding Round, Series B
Japan, United States, Israel

Portfolio highlights

LayerX — LayerX which promotes the digitization of business processes utilizing technologies such as blockchain technology.
Commune — Commune is a developer of a platform that supports connections, community building, and customers between organizations and people.
Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Sumitomo Mitsui Banking Corporation (SMBC) and its group companies offer a broad range of financial services centered on banking. They are also engaged in the leasing, securities, credit card, investment, mortgage securitization, venture capital and other credit related businesses. The following lists the activities of SMBC, its subsidiaries andaffiliates in the various business segments.

Investment focus

Information Technology, Software, Health Care
Funding Round, Series A, Series B
Japan, United States, Singapore

Portfolio highlights

Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
Visual Bank — Visual Bank operates a stock photo business and provides an AI data platform. It aims to create a society in which the value of Japanese creations is maximized and optimized.
Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Keio Innovation Initiative (KII) is a venture capital established by Keio University. In order to make more effective use of the research results of Keio University, we aim to contribute to the development of society by creating investment for venture companies that utilize research results and creating new industries.The key to thinking aboutJapan's future growth strategy is to utilize advanced research results of the university. In addition to GDP, in addition to GDP, Japan is the world's third largest R & D exporter in R & D expenses, but as the low growth rate shows, it has a problem in investment efficiency in research and development. There are also reports on the entrepreneurial spirit that is indispensable for creating new industries, with the lowest entrepreneurial activity rate among developed countries.

Investment focus

Health Care, Medical, Biotechnology
Series A, Funding Round, Seed
Japan, United Kingdom

Portfolio highlights

Waku — Waku is a manufacturing company that specializes in the research and development of organic fertilizers for the agriculture industry.
Fermelanta — Fermelanta produces rare plant-based ingredients through microbial fermentation. It engineers a cell to build a biosynthetic pathway of target molecules with gene transfer and disruption.
Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Senshu Ikeda Capital offers financial consultancy services.

Investment focus

Software, Internet, Information Technology
Funding Round, Seed, Series A
Japan

Portfolio highlights

HOLO BIO — HOLO BIO is a research and technology firm that employs biological breeding techniques to address the food challenges faced by humanity.
EX-Fusion — EX-Fusion develops the first commercial laser based nuclear fusion reactor for power generation.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.

Nippon Venture Capital ("NVCC"), established in 1996 as one of the few largest Japanese independent venture capital firms, is destined to undertake the unprecedented task of providing full-range venture capital services in cooperation with major Japanese business leaders and leading companies, which have supported and nurtured various newbusinesses on their own, as well as proactively developing new venture enterprises.

Investment focus

Software, Health Care, Information Technology
Funding Round, Series A, Seed
Japan, United States

Portfolio highlights

Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
Upward — UPWARD is highly by linking CRM · schedule map / location information, is a cloud service for the visiting business of field sales easier. Field salespersons who have many customers and who are out of the office feel that it is difficult to grasp all customers to Kampek and measure the timing of visits no matter how memorable they are.
Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

SBI Investment supports the business development and growth of private venture companies through fund investment. It manages and manages venture capital funds under the management philosophy of becoming a leading company responsible for the creation and development of core industries in the 21st century as a "new industry creator".SBIInvestment has invested in a total of 986 companies in the past, of which 169 (17.1% of investment companies) have exited through IPO or M & A.

Investment focus

Information Technology, Software, Financial Services
Series B, Series A, Funding Round
Japan, South Korea, United States

Portfolio highlights

Prorata.AI — ProrataAI builds technology that enables generative AIs to properly attribute contributing content and share revenues on a per-use basis.
Innovacell — Innovacell is a biotechnology firm entirely focused on the area of tissue engineering and it operates one of Europe's largest and most modern production facilities for the proliferation of the body's own tissue cells. Its supervisory board is chaired by the experienced financial expert, Dr. Harald Pöttinger, a director of Alpine EquityManagement AG, based in Bregenz, Austria. Innovacell currently employs 20 staff as well as numerous outside experts.
ASTRO — Situs Belanja Kebutuhan Harian Online dengan Harga Terjangkau dan Kualitas Terbaik. Pesan Kebutuhan Harian di ASTRO Pasti Sampai dalam Hitungan Menit

Angel Bridge is a angel investor groups in Japan and provide high quality and abundant funds to excellent companies.

Investment focus

Information Technology, Software, Consulting
Series A, Seed, Funding Round
Japan

Portfolio highlights

Fermelanta — Fermelanta produces rare plant-based ingredients through microbial fermentation. It engineers a cell to build a biosynthetic pathway of target molecules with gene transfer and disruption.
Goals — Goals specializes in development, sales and operational support for cloud services for food service companies.
Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.

Incubate Fund is an independent early-stage venture capital that specializes in providing capital to technology startups at the seed stage. The firm built a portfolio of over 300 companies in Asia, taking 12 companies to public and 20 companies to M&A exit since 2010.

Investment focus

Software, Information Technology, E-Commerce
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

Visual Bank — Visual Bank operates a stock photo business and provides an AI data platform. It aims to create a society in which the value of Japanese creations is maximized and optimized.
Nominal — Nominal empowers the next-generation economy.Nominal modernizes and automates accounting and financial management, providing robust reporting, multi-entity consolidation, workflow automation (including accruals and revenue), lease compliance (ASC 842/IFRS 16), period-end close collaboration, and much more.Nominal's generativesubledgers transform business logic into actions and insights using Generative AI - without the need for costly engineering or lengthy IT projects. Our shadow-ledger is implemented in days, not months, and seamlessly integrates with existing general ledgers and ERPs.
Rocket Link Technology — Rocket Link Technology is a product development company that specializes in designing LTP rockets for space travel.

ANRI is a Japanese venture capital firm that mainly invests in seed and early-stage startups.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Funding Round
Japan, United States, India

Portfolio highlights

Chorakuchoju — Chorakuchoju is a healthcare organization that tries to avoid isolation by implementing AI technologies and medical services.
Linea Innovations — Linea Innovations is an energy production company that develops commercial fusion reactors with advanced fuel technology.
Strand Therapeutics — Strand Therapeutics is developing the first platform for creating programmable mRNA drugs to deliver precise, multi-functional, potentially curative treatments.

Mizuho is the venture capital firm affiliated to Mizuho Bank, the second-largest Japanese bank in terms of assets. The firm has headquarters in Tokyo.The firm has ¥49.6 billion JPY under management, focusing on information technology and biotechnology investments. Over 600 Mizuho companies have gone public. According to Nikkei, Mizuho is thefifth-largest venture capital firm in Japan.Mizuho Capital was formed in 2002 by the merger of Fujigin Capital, Tokyo Venture Capital and IBJ Investment. Three firms were subsidiaries of Fuji Bank, Dai-Ichi Kangyo Bank and the Industrial Bank of Japan respectively.

Investment focus

Information Technology, Software, Internet
Funding Round, Series A, Series B
Japan, United States, China

Portfolio highlights

Terass — TERASS is a High-end real estate information site.
Helical Fusion — Helical Fusion is a startup company that aims to commercialize fusion energy using magnetic confinement of high-temperature plasmas.
Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Real Tech Japan is a venture capital firm that seeks to invest in innovative R&D technology companies. Realtech Fund is a joint venture between the Ministry of Economy, Trade, and Industry and NEDO (New Energy and Industrial Technology Development Organization). The firm was founded in 2014 and based in Tokyo, Japan.

Investment focus

Manufacturing, Biotechnology, Medical
Funding Round, Series A, Seed
Japan, Singapore, Austria

Portfolio highlights

Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.

PALTEK offers semiconductor products to electronics manufacturers and design consignment services.

Investment focus

Medical, Software, Life Science
Series A
Japan

Portfolio highlights

HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.

Sosei CVC is support the creation and growth of life science companies.

Investment focus

Biotechnology, Medical, Pharmaceutical
Funding Round, Series A, Series B
Japan

Portfolio highlights

StemRIM — Stem Rim is a biotechnology company aiming to develop “regenerative medicine”.We are developing drugs based on a new mechanism of action that mobilizes stem cells present in the living body to the injured or diseased tissue without removing them out of the body and induces functional tissue regeneration.
Chromocenter — Chromocenter is a next generation biopharmaceuticals Manufacturing company. It uses technologies such as artificial chromosome vectors, mainly for drug discovery such as medical pharmaceuticals
Stem Cell & Device Laboratory — Stem Cell & Device Laboratory is aiming to contribute to a healthy society with new cell application products.

Japan Science and Technology Agency is an integrated organization of science and technology that implements science and technology policy in Japan. It handles many projects, including the government’s Science and Technology Basic Plan and knowledge creation. The European Sustainability School ESSSR is the owner of Japan Science and TechnologyAgency.Japan Science and Technology Agency undertakes its task in a comprehensive manner. It also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.Japan Science and Technology Agency is headquartered in Tokyo, Japan.

Investment focus

Medical, Biotechnology, Health Care
Funding Round, Series A, Series B
Japan

Portfolio highlights

OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Kaga Electronics is a Japan based company engages in the sales of electronic components, electronic devices and other. It operates through following segments: Electronic Components, Information Equipment, Software and Other. The firm generates majority revenue from the Electronic Components.

Investment focus

Education, Internet, Artificial Intelligence
Funding Round, Series A, Seed
Japan, Taiwan

Portfolio highlights

Bonx — GO MAKE NOISE
17LIVE — Flip action technology, connect the world together; integrate instant audio and video into life, and create a new generation of action audio and video. No matter where you are, in any corner of the world, you can connect with the world anytime, anywhere through the 17LIVE platform, show your talent and enthusiasm, realize your dreams, and createyour own wonderful life.
Linkage — Linkage is a Online health support business and Online specific health guidance.

Sompo Holdings provides property and casualty insurance, life insurance, and other financial services. In addition to the core businesses of domestic non-life insurance business, overseas insurance business, domestic life insurance business, and long-term care/senior business, they will develop new business strategies in the fields of digitaland healthcare.It was established in 2010 and is based in Shinjuku-ku, Tokyo, Japan.

Investment focus

Health Care, Analytics, Nursing and Residential Care
Series B, Series A, Funding Round
Japan, Israel, Taiwan

Portfolio highlights

Allm — Allm is a medical ICT company dedicated to shaping healthcare. The company seeks to benefit society by launching next-generation technologies and medical communications platforms for the healthcare industry. The solutions are installed more than 18 countries across US, South America, EU, Japan, Middle East and Africa.
Wejo — We unlock limitless possibilities with connected vehicle data
Pulsora — Pulsora is the all-in-one platform for enterprise sustainability management, helping companies collect, report, and improve their ESG and sustainability performance.

Fast Track Initiative is a venture capital firm with an exclusive focus on life sciences and healthcare services.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series A, Series B
Japan, United States, United Kingdom

Portfolio highlights

Medii — Medii provides a physician sharing service for hospitals.
A10 Lab — A10 Lab is a company that aims to makes people happy with technology that is independent of Sony's new business creation program. It provides Google Play an app that allows users to do things that they have never been able to do with the custom app 'Min Chale' selected for two consecutive years. It is a company that brings profits tocompanies by improving lifetime value (sales) through the habitation of users that companies have.
CellFiber — Cell fiber technology was developed as a basic technology for handling cells in the engineering field.

SPARX Group Co., Ltd. is an independent Asia-based equity and credit asset management services and Asian fund financial specialist with offices in Tokyo, Hong Kong and Seoul for global institutional and individual investors, including financial advisors and financial planners, with alternative strategies (including activist, short-enabled, private equity and quantitative and fund-of-funds) and mutual funds (through SPARX Asia Funds such as SPARX Asia Pacific Opportunities Fund, SPARX Asia Pacific Equity Income Fund, SPARX Japan Smaller Companies Fund and SPARX Japan Fund) managed or sub-advised by SPARX Asset Management Co. Ltd., SPARX Asia Investment Advisors Limited and Cosmo Asset Management Co., Ltd.

Investment focus

Software, Artificial Intelligence, Information Technology
Funding Round, Series B, Series A
Japan, United States, China

Portfolio highlights

Blue Skies Space — Blue Skies Space provides access to space science data from low-cost space missions.
Blue Laser Fusion — Blue Laser Fusion is a commercial fusion company. Blue Laser Fusion is a laser startup to commercialize laser fusion by inventing its own laser and fusion reactor.
Nanofiber Quantum Technologies — Powering a globally connected quantum future with pioneering nanofiber cavity QED.

Fuyo General Lease focuses in the leasing and installment sales trading of equipment and fixtures, and financial transaction. The company provides leasing services of information-related equipment, office equipment, and industrial equipment, installment sales of commercial facilities, production facilities, and hospital facilities. It also providessecurities management services and anonymous association composition.Fuyo General Lease was founded on 1969 and is headquartered in Tokyo, Japan.

Investment focus

Manufacturing, Biotechnology, Sales
Series A, Funding Round, Corporate Round
Japan

Portfolio highlights

avatarin — avatarin develops next-generation mobility and human augmentation platforms.
A.L.I. Technologies Japan — Aerial Lab Industries focuses on research and development of UAV (unmanned miniature aircraft).
3D Printing Corporation — 3D Printing Corporation provides 3D printing technology solutions.

Lifetime Ventures is a VC firm that specializes in pre-seed and seed investments.

Investment focus

Health Care, Software, Medical
Seed, Funding Round, Pre-Seed
Japan, South Africa, United Kingdom

Portfolio highlights

Kinish — Kinish is a company leading a revolution in dairy products. To achieve environmentally friendly and delicious dairy products, we are developing a special rice variety that produces milk proteins.
Kwahuu Ocean — Kwahuu Ocean develops sustainable squid farming systems.
Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

WASEDA University Ventures (WUV) is a venture capital firm specialising in founding investments by creating new start-up companies that make use of academia and are based on "the practical application of scholarship". Our mission is to be a capitalist that implements academic knowledge and

Investment focus

Laser, Commercial, Manufacturing
Seed, Convertible Note
Japan, United States

Portfolio highlights

VETA — VETA strives to minimize friction caused by value differences in society through cutting-edge social science research.
Pestalozzi Technology — Pestalozzi Technology is a development and provision of educational products in the fields of physical education and club activities.
Power Diamond Systems — Power Diamond Systems is a research and development firm that focuses on diamond semiconductor devices.

Innovation Engine has been is promoting investment to create and grow promising business areas created from technology.

Investment focus

Software, Information Technology, Health Care
Funding Round, Series A, Series C
Japan

Portfolio highlights

Asilla — Asilla develops and provides AI specialized in image and video analysis. Its services, the Vehicle recognition AI, recognizes the manufacturer and model from the image of the vehicle. It also has a censorship service that detects inappropriate images that can not be released, including copyrights and obscene expressionsAsilla was founded in 2015and is based in Tokyo, Japan.
Ranimaru — Ranimaru is pet service providing company that offers pet sitting, care of your pet dog in events, professional course about pet sitting.
Drone Show Japan — Drone Show Japan company specializes in drone shows for events, aerial photography, and workshops.

Mitsui Mining & Smelting Company, Ltd. mainly produces non-ferrous metal such as lead and copper alloys.

Investment focus

Life Science, Renewable Energy
Series A
Japan

Portfolio highlights

Atomis — Atomis provides global solutions for precisely controlling gases. Its core technology, porous coordination polymers (PCPs; also known as metal-organic frameworks (MOFs)), is based on research developed by Distinguished Professor Susumu Kitagawa at the Institute for Advanced Study at Kyoto University. It aims not only to provide solutions such asthe optimization for manufacturing processes of PCPs but to also develop applications that provide innovative value using these materials.It was founded by Masakazu Higuchi in 2015 and is headquartered in Kyoto, Japan.
Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.
Chitose Group — CHITOSE GROUP is a family of biotechnology companies operating mainly in Southeast Asia and Japan with an aim of leaving mankind with an environment where they can live in abundance for over a thousand years. CHITOSE GROUP is creating new values in the fields of agriculture, medical, food, energy, chemistry and others through “Technologicaldevelopment capabilities in the biotechnology field by constantly promoting economic rationality” and “Business development capabilities for drawing a path towards commercialization by understanding the essence and limitations of biotechnology”.

Hiroaki Kitano is the SVP at Softbank Mobile. He attended Waseda University.

Investment focus

Health Care, Information Technology, Fitness
Seed, Angel, Debt Financing
Japan, United States

Portfolio highlights

GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
Epistra — Epistra accelerates research and development in life sciences.
Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.

DBJ Capital Co., Ltd. was founded in June 2010 through the integration of two venture capital firms of the DBJ Group, New Business Investment Co., Ltd. and Intellectual Properties Development & Investment, Inc. We are a wholly-owned subsidiary of Development Bank of Japan Inc.At DBJ Capital, we focus on venture firms which use newtechnologies and business models to grow and compete on the global market, regardless of their industry or scale. To meet the particular needs of each client, we mobilize the entire DBJ Group to arrange the best investment solutions, ranging from growth-spurring equity investment to financing schemes drawing on DBJ's vast networks.We also assist in venture start-ups. Our value enhancement team provides the kind of comprehensive, hands-on support needed to commercialize outstanding intellectual property and technologies developed by firms, research labs, and universities, and to carve out a place for them in the market.DBJ Capital will continue to play in a part in Japan's economic revival - by helping the firms we invest in to grow, and by encouraging the creation of new industries in Japan.

Investment focus

Software, Health Care, Medical
Funding Round, Series A, Series B
Japan, United States, Australia

Portfolio highlights

Anaguma — Anaguma handles business development based on the philosophy of helping people with a sustainable structure. The company's business objective is to eliminate concerns about purchases and reservations, and it delivers before-sales social networks. It also provides matching services exclusively for housekeepers' personal contracts. Thecompany also offers influencer marketing services with a focus on removing waste completely from advertising and realizing a world in which good products can be sold regardless of advertising costs.Anaguma was founded in January 2016 and is headquartered in Tokyo, Japan.
Ageless — Ageless is a staffing agency that provides human resources-related services primarily to middle-aged and senior citizens.
Forest — Forest Co., Ltd. operates as an e-commerce aggregator, seeks to identify sustainable, high-quality products and brands that embrace the spirit of Japan and help them grow and enter the global market by using the power of technology.

Delight Ventures is a venture capital firm that thoroughly reduces the hurdles of entrepreneurship in Japan and supports entrepreneurs in the world. Entrepreneurship is taken as a natural career path, and we aim to be a society where both successful and unsuccessful people can continue to take on challenges.

Investment focus

Software, Artificial Intelligence, Information Technology
Seed, Series A, Series B
Japan, United States, South Korea

Portfolio highlights

KAUCHE — KAUCHE is a social commerce app. They provide services for online and mail-order retail shops. Their customers' inquiries are addressed through phone, email, and online applications.
OSHIAI — OSHIAI is an AI chat software that lets you communicate with your favorite idol's "Ai" avatar, which represents their hobbies, preferences, and speaking style.
NaLaLys — NaLaLys is a business consulting firm that provides management, distribution, research, and consulting services.

Media Future is a group of communication technology professionals that works on connecting feelings and thoughts. The Tokyo, Tokyo-based company was established in 2013.

Investment focus

Medical, Biotechnology, Genetics
Series A, Funding Round
Japan

Portfolio highlights

HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
HekaBio — HekaBio connects world-leading healthcare innovations to unmet medical needs in the Asia Pacific, with broad category development expertise in pharma, medical device, in-vitro diagnostics, digital health, and cell & gene therapies.
Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).

Will Capital Management is a capital management company that specializes in business development consulting and principal investment.

Investment focus

Aquaculture, Life Science, Biotechnology
Seed
Japan

Portfolio highlights

HOLO BIO — HOLO BIO is a research and technology firm that employs biological breeding techniques to address the food challenges faced by humanity.

Mobile Internet Capital (MIC) keeps up on the latest developments of Mobile Internet technologies and services at a high level, and continues to be a venture capital with both technical expertise and execution capability.

Investment focus

Software, Mobile, Internet
Funding Round, Series A, Seed
Japan, United States, China

Portfolio highlights

KAKEAI — Amazon S3 is cloud object storage with industry-leading scalability, data availability, security, and performance. S3 is ideal for data lakes, mobile applications, backup and restore, archival, IoT devices, ML, AI, and analytics.
Amptalk — Amptalk is a software development firm specializing in operating automatic transcription and analysis of online business negotiations.
Recustomer — Recustomer is an IT company that develops software for digital payment and provides support for web development.

FueTrek provides a better and faster way to communicate through with speech recognition, speech dialogue, and speech translation.

Investment focus

Mobile, Robotics, Health Care
Series A
Japan

Portfolio highlights

Yukai Engineering — YUKAI Engineering - THE ROBOT COMPANY

Capital Medica Ventures is a venture capital firm based in Tokyo, Japan with a focus on startups in the healthcare industry.Capital Medica Ventures is a venture capital that operates a venture fund specializing in the healthcare field. It is the only healthcare-specialized VC in Japan that can provide 30 medical institutions as a business trialfield.

Investment focus

Medical, Software, Health Care
Seed, Series A, Funding Round
Japan

Portfolio highlights

HCMJ — HCMJ specializes in software development in the medical industry.
Epigno — Epigno provides hospital management systems for medical institutions.
Rehab — Rehab for Japan is developing a special rehabilitation SaaS for day service .

Mitsubishi Gas Chemical contributes to societal growth and harmony by creating a wide range of value through chemistry.

Investment focus

Pharmaceutical, Chemical, Medical
Series A, Funding Round, Seed
Japan, United States

Portfolio highlights

Resource Chemical — Resource Chemical develops CO2 into high-performance plastics that do not pollute the environment. The company's headquarters are in Berkeley, California.
Albatross Technology — Albatross Technology is a technology company that develops offshore renewable energy devices and floating offshore wind turbines.
TKG Therapeutics — Tokyo Nucleic Acid Synthesis is a pharmaceutical company that focuses on developing nucleic acid drugs using new-age medical technology.

ReBoost specializes in recruiting and training business.

Investment focus

Content, Medical, Hospital
Seed, Pre-Seed, Funding Round
Japan

Portfolio highlights

Medii — Medii provides a physician sharing service for hospitals.
digzyme — Digzyme is a research and development platform for creating, discovering, and evaluating new enzyme-catalyzed reactions by bioinformatics.
viviane — viviane is running Japan's best video streaming guide, 1Screen.

HERO Impact Capital is a venture capital firm that co-founds research and development startups.

Investment focus

Solar, Security, Aerospace
Series A, Pre-Seed, Series B
Japan

Portfolio highlights

ChillStack — ChillStack provides information on AI, security, and development.
toggle — toggle is the social implementation of technology in the real estate area.
Cosmobloom Co. — Cosmobloom Co. is a manufacturing company that analyses, designs, and develops space solar power generation systems and solar power sails.

Genesia Ventures is a venture capital firm focused on seed/early stage startups in Japan and Southeast Asia. Since it's inception in Dec 2016, Genesia Ventures has invested in over 90 companies in Japan, Indonesia, Vietnam, Singapore and the US. Genesia Ventures invests in various sectors: SaaS, marketplace, Media, Finance, Insurance,RealEstate, Healthcare, Medical, Travel, Education, Manufacturing, Construction, HR, Agriculture, Sports, Retail, Entertainment, etc.

Investment focus

Information Technology, Software, Health Care
Seed, Series A, Funding Round
Japan, Vietnam, Indonesia

Portfolio highlights

Nonat — Nonat is a company focused on supporting the future of women and children by driving innovation across generations. It is developing a foundational model specifically designed to address the needs of women and children.
Miresso — Miresso is a startup firm that offers nuclear fusion power generation services through natural resources.
MetaSensing — MetaSensing specializes in the development, manufacturing, and commercialization of advanced attachable Raman sensors, designed to provide precise, real-time chemical and molecular analysis across a wide range of applications, including pharmaceuticals, biotechnology, environmental monitoring, and industrial process control.

Energy & Environment Investment, Inc. (EEI) is Japan’s first venture capital specialized in the clean technology sector. With core members who have rich hands on experience in founding and managing venture companies, we aim to provide risk money and various strategic values to promising venture companies and businesses.

Investment focus

Software, Energy, Internet of Things
Funding Round, Series A, Series B
Japan, United States, Germany

Portfolio highlights

Asusola — Asusola engaged in the renewable energy power generation business
Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
NABLA Mobility — Solving the complexities involved in the "Operation of Fleets" of Mobility and support its evolution and decarbonization

Chuo Shinkin Venture Capital is a venture fund of Kyoto Chuo Shinkin Bank

Investment focus

Health Care, Sales, Food Processing
Series A, Funding Round, Seed
Japan

Portfolio highlights

Thyas — Thyas Co. Ltd. provides preparations of regenerative immunocell therapy for cancer and infection.
Regional Fish — Regional Fish provides seed, seedlings, aquaculture methods and fisheries services.
Space Power Technologies — Space Power Technologies (SPT) was founded in 2019 as Japan's first start-up for “Spatial Transmission Wireless Power Transmission (WPT)”. We will harmonize elemental technologies cultivated through academics with people and society, and solve social issues related to power supply.

Kyogin Lease & Capital is an investment firm that specializes in the leasing, stock and bond investment and public offering consulting.

Investment focus

Manufacturing, Task Management, Medical
Funding Round, Series A, Series B
Japan

Portfolio highlights

KOMPEITO — Office de Yasai is an online platform that enables users to order and get vegetables delivered to their offices. The platform’s operations are based in Tokyo, Japan.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.

QB Capital is make equity investments in venture companies.

Investment focus

Manufacturing, Medical, Biotechnology
Funding Round, Seed, Series A
Japan, Singapore, United States

Portfolio highlights

Alumnote — The alumni association management software developed by Alumnote allows schools to manage their alumni associations online. The focus of the company is to undertake loyalty building and marketing for potential donors such as graduates and provides digital tools, and supports the execution of donation acquisition.
Equmenopolis — Equmenopolis is an information services company that specializes in conversational AI agent platforms and application developments.
Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.

CareNet is a marketing company providing various solutions to pharma companies through the management of media specialized in medical/pharmaceutical education for HCPs. For more than 20 years and since its foundation in 1996, CareNet has continually provided places for exchanging therapeutic information, as well as valuable solutions to HCPsand pharmaceutical companies from the position of the No. 1 media in clinical medical education.

Investment focus

Life Science, Biotechnology, Health Care
Series A, Series B, Series C
Japan, United States

Portfolio highlights

Modalis Therapeutics — Modalis Therapeutics Corporation is an biotech company focusing on developing transformative therapeutics for unmet medical needs using its proprietary technologies on CRISPR and protein engineering platforms. The company has a strong foundation on intellectual property licensed from the University of Tokyo.
DiscGenics — DiscGenics is focused on developing regenerative therapies that alleviate pain and restore function in patients with degenerative diseases of the spine.

Kenshin is a CEO at Hacarus Inc., a healthcare technology startup based in Kyoto, Japan.He co-founded several tech startups with 2 exits in the past 15 years. His first career started as an engineer at Sony Computer Entertainment and worked on PlayStation development projects. HIs fist startup was acquired by Japanese public company, and thesecond startup was sold to the US company.Born in 1976. He holds a Computer Science degree from California State University. He loves mountain hiking and currently living in Kyoto Japan with his wife and family.

Investment focus

Mobile, Medical, Software
Seed, Series A
Japan

Portfolio highlights

Helpfeel — Our vision is to make saving, sharing, and exploring ideas as natural as breathing. On this journey we're humbled to be helping millions around the world from solo makers to university research labs, from gamers to pro designers, and large to small teams like ours.
HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.

Chushin Venture Capital is a venture capital fund established by Kyoto Chuo Shinkin Bank.

Investment focus

Retail, Travel, Home Decor
Series A, Series B
Japan

Portfolio highlights

Cizucu — Cizucu is a stock photo community that helps creators and brands to create photos.
HOLO BIO — HOLO BIO is a research and technology firm that employs biological breeding techniques to address the food challenges faced by humanity.
RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Japan Finance provides a diversified portfolio of financial services to the small and medium enterprise sector.

Investment focus

Software, Information Technology, Internet
Debt Financing, Funding Round, Seed
Japan, India, Hong Kong

Portfolio highlights

AirKamuy — AirKamuy is an aviation company that designs and manufactures fixed-wing VTOL aircraft and drones with the help of modern technology.
Haul — Haul is a human resources company that provides recruitment consulting and marketing SaaS development services.
Sorabito — SORABITO is an eCommerce marketplace for used construction equipment and machinery.

Japan Materials Technology commercializes necessary material innovations for society.

Investment focus

Chemical, Software, Recruiting
Funding Round, Series A, Seed
Japan

Portfolio highlights

Tryeting — TRYETING provides an AI platform that integrates various types of software. One of the strengths of the company is materials informatics, a field that applies the techniques of informatics, such as AI and big data, to materials. This approach can significantly speed the development of new materials.
TopoLogic — TopoLogic designs and manufactures heat flow sensors, thermoelectric conversion devices, and topological and novel spintronics materials.
Sotas — Sotas provides services to chemical trading companies and bridges the gap between raw material producers and consumers.

Shoji Okamoto is the President of Mirai Works.

Investment focus

Lifestyle, Life Science, Service Industry
Seed
Japan

Portfolio highlights

Mono.un — Mono.un provides users with opportunities to meet authors and collaborate on tales and specializes in bringing exciting experiences full of stories of Japanese culture to the world.
Memory Lab — Memory Lab is a research laboratory that offers AI paper analysis and development solutions.

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