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Top 50 Biotech Startup Investors in Japan in May 2025

Last updated: May 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Biotech startups based in Japan. We rank investors based on the number of investments they made in Biotech companies from Japan. We update this investor list every month.

Top 50 Biotech Startup Investors in Japan in May 2025

Investor	Biotech Japan investments
Mitsubishi UFJ Capital	18
UntroD Capital	17
Fast Track Initiative, Inc.	15
Osaka University Venture Capital	15
SMBC Venture Capital	13
UTEC - The University of Tokyo Edge Capital Partners	12
ANRI	12
JAFCO	11
Keio Innovation Initiative	10
Real Tech Japan	9
SBI Investment	8
Mizuho Capital	8
DBJ Capital	7
Nissay Capital	7
Japan Science and Technology Agency	6
Future Venture Capital	6
Miyako Capital	5
Nippon Venture Capital	5
Senshu Ikeda Capital	4
F-Prime Capital	4
Remiges Ventures	4
Fujifilm	4
Incubate Fund	4
FFG Venture Business Partners	4
DG Daiwa Ventures	3
KSP	3
Tsukuba Institute of Research	3
Chushin Venture Capital	3
Takeda	3
Takeda Ventures	3
D3	3
Eight Roads Ventures	3
Kyogin Lease & Capital	3
JIC Venture Growth Investments	3
Sosei CVC	3
Japanese Organization for Medical Device Development	2
Capital Medica Ventures	2
Yokohama Capital	2
Koki Yabu	2
Tohoku University Venture Partners	2
Chugin Capital Partner	2
NEC Capital Solutions	2
Spiral Capital	2
The Awa Bank	2
Coral Capital	2
Japan Asia Investment	2
TechAccel Ventures	2
UTokyo Innovation Platform	2
Global Brain Corporation	2
Primal Capital	2

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Investor list

Mitsubishi UFJ Capital is a venture capital firm focusing on life science, ICT, and high technology investments.

Investment focus

Information Technology, Software, Health Care
Funding Round, Series A, Series B
Japan, United States, Singapore

Portfolio highlights

Manabie — Manabie is an Education Technology start-up company on a mission to provide a new style of online & offline merged learning around the world. We provide students with everything they need for efficient learning; high-quality learning materials, great learning environments, personal coaches and more! We believe that our new method of learning,integrating online and offline will dramatically innovate the way students learn.
M&A Cloud — M & A is a Match Platform for Small & Medium Venture Companies
NABLA Mobility — Solving the complexities involved in the "Operation of Fleets" of Mobility and support its evolution and decarbonization

UntroD Capital is an R&D-based innovative technology that specializes in social implementation.

Investment focus

Manufacturing, Biotechnology, Robotics
Funding Round, Seed, Series A
Japan, Singapore, India

Portfolio highlights

Alternō — Alternō was founded with a vision to create Asia's first low-cost thermal energy storage solution for renewable energy, to be deployed widely across the region by 2050. Alternō received early stage funding from Antler VC in Jan 2023 to kick off the research & development.
Q5D Technology — Additive manufacturing with conductors. Eliminate traditional wiring, saving space and weight. Unique 5-axis robots add power and data functions to products. Simplify supply chains and manufacturing. Transform productivity with our hardware, software, and support.
Optieum Biotechnologies — Optieum Biotechnologies Inc. is a pre-clinical stage biotechnology company committed to developing innovative scFv antibody-based therapies for the treatment of patients with cancers. Their proprietary platform technology, Eumbody System™, enables to develop and detect a scFv-based product candidates that specifically bind to, and modulate tooptimize the immune-cell function for oncology targets.We are committed to helping patients with severe diseases by bringing life-changing therapies to the patients in need.

Fast Track Initiative is a venture capital firm with an exclusive focus on life sciences and healthcare services.

Investment focus

Health Care, Biotechnology, Medical
Series A, Seed, Funding Round
Japan, United States, United Kingdom

Portfolio highlights

Medii — Medii provides a physician sharing service for hospitals.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Osaka University Venture Capital is a venture capital firm that focuses on early-stage ventures in the fields of life innovation, green innovation, and platform technology. The firm was founded in 2014 and based in Osaka, Japan.

Investment focus

Biotechnology, Manufacturing, Health Care
Funding Round, Seed, Series A
Japan

Portfolio highlights

Ayumo — Ayumo is a research and development company that provides deep learning services with medical insights and AI technology.
QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .

Sumitomo Mitsui Banking Corporation (SMBC) and its group companies offer a broad range of financial services centered on banking. They are also engaged in the leasing, securities, credit card, investment, mortgage securitization, venture capital and other credit related businesses. The following lists the activities of SMBC, its subsidiaries andaffiliates in the various business segments.

Investment focus

Information Technology, Health Care, Software
Funding Round, Series B, Series A
Japan, United States, Singapore

Portfolio highlights

Ababa — Ababa provides recruitment and employment solutions.
DelizMart — Deliz Mart is a digital-driven platform that helps to solve food distribution challenges and reduce cost transactions in the food industry.
Penetrator — Penetrator transforms the real estate market with space technology, tackling transaction issues and forming landslide observation systems.

UTEC-The University of Tokyo Edge Capital Partners Co., Ltd.. UTEC is a seed/early stage technology focused venture capital firm associated with The University of Tokyo.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Funding Round
Japan, United States, Singapore

Portfolio highlights

Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
Aerem — Make the switch to rooftop solar effortlessly with Aerem solution's innovative solar finance and technology solutions. Discover how we're making solar adoption easier than ever before and start saving on your energy costs.
Piece — Piece is a digital real estate platform offering the easiest and most transparent way to participate in income-producing real estate in Europe. Our mission is to make real estate ownership inclusive and more accessible.

ANRI is a Japanese venture capital firm that mainly invests in seed and early-stage startups.

Investment focus

Software, Information Technology, Health Care
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

iiba — Iiba is a geospatial platform that specializes in providing location information related to child-rearing.
AiCAN — AiCAN provides system planning and development, data analysis, IT, and consulting services related to child welfare.
Asusola — Asusola engaged in the renewable energy power generation business

Since its founding in 1973, JAFCO has always worked with leading-edge entrepreneurs. The total capital commitments of its investment funds in Japan and overseas have exceeded 1 trillion yen and the number of portfolio IPOs to date has reached over 1,000. In addition to venture investment, JAFCO also carries out buyout investment and commit to thecreations of innovative technologies and services worldwide. As entrepreneurs’ closest partner in bringing their visions to life, JAFCO provides support in areas of HR, marketing/ sales, and back-office operations, in addition to providing financing.

Investment focus

Information Technology, Software, Artificial Intelligence
Series A, Funding Round, Series B
Japan, United States, Israel

Portfolio highlights

Sanu — SANU is a subscription service that offers a home in nature.
Pocket Sign — Pocket Sign develops digital platforms that store e-signatures and other authentication details for it's users privacy and security.
Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Keio Innovation Initiative (KII) is a venture capital established by Keio University. In order to make more effective use of the research results of Keio University, we aim to contribute to the development of society by creating investment for venture companies that utilize research results and creating new industries.The key to thinking aboutJapan's future growth strategy is to utilize advanced research results of the university. In addition to GDP, in addition to GDP, Japan is the world's third largest R & D exporter in R & D expenses, but as the low growth rate shows, it has a problem in investment efficiency in research and development. There are also reports on the entrepreneurial spirit that is indispensable for creating new industries, with the lowest entrepreneurial activity rate among developed countries.

Investment focus

Health Care, Medical, Biotechnology
Funding Round, Series A, Seed
Japan

Portfolio highlights

JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.
Linqmed — Linqmed is a pharmaceutical company that specializes in the research and development of radiopharmaceuticals for cancer treatment.
Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.

Real Tech Japan is a venture capital firm that seeks to invest in innovative R&D technology companies. Realtech Fund is a joint venture between the Ministry of Economy, Trade, and Industry and NEDO (New Energy and Industrial Technology Development Organization). The firm was founded in 2014 and based in Tokyo, Japan.

Investment focus

Manufacturing, Biotechnology, Medical
Funding Round, Series A, Seed
Japan, Singapore, Austria

Portfolio highlights

Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.

SBI Investment supports the business development and growth of private venture companies through fund investment. It manages and manages venture capital funds under the management philosophy of becoming a leading company responsible for the creation and development of core industries in the 21st century as a "new industry creator".SBIInvestment has invested in a total of 986 companies in the past, of which 169 (17.1% of investment companies) have exited through IPO or M & A.

Investment focus

Information Technology, Software, Financial Services
Series B, Series A, Funding Round
Japan, South Korea, United States

Portfolio highlights

Zolve — Best neo bank in India offering international banking & financial services online. Apply for a US bank account, credit card & student education loan with Zolve!
Zerodoor HD — Zerodoor HD specializes in digital transformation in constructing industry.
TOKYO GameFi — TOKYO GameFi is a Web3 firm formed by a management team of developers and engineers with previous experience at CyberAgent.

Mizuho is the venture capital firm affiliated to Mizuho Bank, the second-largest Japanese bank in terms of assets. The firm has headquarters in Tokyo.The firm has ¥49.6 billion JPY under management, focusing on information technology and biotechnology investments. Over 600 Mizuho companies have gone public. According to Nikkei, Mizuho is thefifth-largest venture capital firm in Japan.Mizuho Capital was formed in 2002 by the merger of Fujigin Capital, Tokyo Venture Capital and IBJ Investment. Three firms were subsidiaries of Fuji Bank, Dai-Ichi Kangyo Bank and the Industrial Bank of Japan respectively.

Investment focus

Information Technology, Software, Internet
Funding Round, Series A, Series B
Japan, United States, China

Portfolio highlights

Quemix — Quemix is an IT company specialized in providing quantum computing solutions.
Plainer — Plainer is an IT company that provides software development, data management, and SaaS solutions.
Unito — Unito offers people a friction-free lifestyle by pursuing optimization of living.

DBJ Capital Co., Ltd. was founded in June 2010 through the integration of two venture capital firms of the DBJ Group, New Business Investment Co., Ltd. and Intellectual Properties Development & Investment, Inc. We are a wholly-owned subsidiary of Development Bank of Japan Inc.At DBJ Capital, we focus on venture firms which use newtechnologies and business models to grow and compete on the global market, regardless of their industry or scale. To meet the particular needs of each client, we mobilize the entire DBJ Group to arrange the best investment solutions, ranging from growth-spurring equity investment to financing schemes drawing on DBJ's vast networks.We also assist in venture start-ups. Our value enhancement team provides the kind of comprehensive, hands-on support needed to commercialize outstanding intellectual property and technologies developed by firms, research labs, and universities, and to carve out a place for them in the market.DBJ Capital will continue to play in a part in Japan's economic revival - by helping the firms we invest in to grow, and by encouraging the creation of new industries in Japan.

Investment focus

Software, Health Care, Medical
Funding Round, Series A, Series B
Japan, United States, Australia

Portfolio highlights

Ababa — Ababa provides recruitment and employment solutions.
Linqmed — Linqmed is a pharmaceutical company that specializes in the research and development of radiopharmaceuticals for cancer treatment.
Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.

Nissay Capital is a venture capital Company specializing in seed, start-up, growth capital, middle stage, and later stage investment.

Investment focus

Health Care, Internet, Information Technology
Funding Round, Seed, Series A
Japan, United States, Ethiopia

Portfolio highlights

CloudLegal — CloudLegal provides AI-powered legal services, combining generative AI with legal expertise to streamline corporate operations.
Blackbox — Blackbox is an entertainment firm that is involved in businesses, including VTuber production, media mix, and live music events.
Knowhere — Knowhere is a company that applies high-performance AI to sports.

Japan Science and Technology Agency is an integrated organization of science and technology that implements science and technology policy in Japan. It handles many projects, including the government’s Science and Technology Basic Plan and knowledge creation. The European Sustainability School ESSSR is the owner of Japan Science and TechnologyAgency.Japan Science and Technology Agency undertakes its task in a comprehensive manner. It also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.Japan Science and Technology Agency is headquartered in Tokyo, Japan.

Investment focus

Medical, Biotechnology, Health Care
Funding Round, Series A, Series B
Japan

Portfolio highlights

OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Future Venture Capital Co., Ltd. is a venture capital firm specializing in early stage investment. The firm invests in diversified investment in a broad range of industrial sectors. It seeks to invest in Japan. The firm prefers to be the lead investor in its portfolio companies. Future Venture Capital Co., Ltd. was founded in 1998 and is based inKyoto, Japan with offices in Tokyo, Aomori, Iwate, Yamagata, Kanazawa, Mie, Sakai, Kobe, and Ehime.

Investment focus

Health Care, Information Technology, Manufacturing
Funding Round, Seed, Series A
Japan, United States, Myanmar

Portfolio highlights

Nagaku — Nagaku is a web magazine that publishes about culture along with web development, PR, marketing, and consulting services.
Perkup — Perkup is a coworking company that conducts off-site meetings and training camps for organizations.
Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Miyako Capital is the venture capital that manages Kyoto University 2nd Venture Fund (KUVF). The company was founded in 2013 and based in Kyoto & Tokyo, Japan. Investment fields are: 1) Life Science, Biotechnology: Drug creation, regenerative medicine, medical beauty equipment, medical services.2) Agri-Food: Industrialization,agricultural and fishery products growth-promoting technology, specified health food, health food.3) Environment, Energy: Alternative energy, and related technologies.4) IT, Electronics: Web, mobile related devices and application, telecommunication technology, security, consumer and business oriented application, mechatronic, robot.5) New services utilizing state-of-art technology.Investment stages: Primary investment stages are initial-growth stages of seed and early. However, we aim at all growth stages and make investment in post-IPO portfolio companies as well as public companies that are related with Kyoto University.

Investment focus

Medical, Biotechnology, Information Technology
Seed, Series A, Series B
Japan, United States, United Kingdom

Portfolio highlights

Peds3 — Peds3 is a digital healthcare platform that specializes in the research and development of pediatric medicine and maternal and child health fields.
Oishii — Oishii Farm provides indoor vertical farming technology. Oishii sells via supermarkets, offering a container of between eight and 11 strawberries for $50 per package. Hiroki Koga and Brendan Somerville started the company in 2017.
Innovative Space Carrier — Innovative Space Carrier is a aerospace company that offers space transportation systems, planning, drafting and technology strategies.

Nippon Venture Capital ("NVCC"), established in 1996 as one of the few largest Japanese independent venture capital firms, is destined to undertake the unprecedented task of providing full-range venture capital services in cooperation with major Japanese business leaders and leading companies, which have supported and nurtured various newbusinesses on their own, as well as proactively developing new venture enterprises.

Investment focus

Software, Health Care, Information Technology
Funding Round, Series A, Seed
Japan, United States

Portfolio highlights

Gecipe — Gecipe is a video service for e-sports players.
Awarefy — Awarefy is a mental health tech startup that offers CBT-based apps to maximize well-being.
Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Senshu Ikeda Capital offers financial consultancy services.

Investment focus

Software, Internet, Information Technology
Funding Round, Seed, Series A
Japan

Portfolio highlights

HOLO BIO — HOLO BIO is a research and technology firm that employs biological breeding techniques to address the food challenges faced by humanity.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

Dinari — Discover Equity Boundless - Simplify everything from equity management and options grant to payroll so that you no longer have to worry about compliance, taxes, or vesting schedules no matter where your employees are.
Toku — Toku helps companies to automate collections and facilitate payment processes. Toku enables companies to optimize the collection of recurring payments.
Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.

Remiges Ventures is a venture capital firm that focuses on groups and businesses in the Japanese academia and pharmaceutical industry.

Investment focus

Biotechnology, Medical, Health Care
Series A, Series B, Seed
United States, Japan, Canada

Portfolio highlights

Immunis — Currently seeking participants for age-related muscle atrophy (sarcopenia) clinical trails
Cyrano Therapeutics — Cyrano Therapeutics is the leader in Smell Loss therapy and smell loss research. Recover your sense of smell today!
KisoJi Biotechnology — KisoJi is a leading next-generation antibody company developing multi-specific antibodies to address difficult targets in oncology and other diseases

Fujifilm develops and sells consumer products and business products related to photography. Fujifilm Holdings Corporation is a Japanese multinational photography and imaging company. The company serves various industries, including medical, graphic arts, optics, enterprise storage, motion picture, and photography.The company’s consumer productsare categorized as digital cameras and accessories, film photography, Instax photography, and binoculars. Its business products are categorized as medical systems, Fujinon endoscopy, microfilm, data storage, graphic arts and printing, professional video, optical devices, specialty chemicals, printing imaging colorants, and more. Color films, digital cameras, photofinishing equipment, color papers, photofinishing chemicals, medical imaging equipment, graphic arts equipment and materials, flat panel displays, and photocopiers and printers are some products developed by Fujifilm USA.Fujifilm USA is based in Minato-ku, Tokyo, Japan.

Investment focus

Biotechnology, Health Care, Medical
Series A, Funding Round, Series B
Japan, United States, China

Portfolio highlights

Ripcord — Ripcord is a robotics company that combines hardware and software robotics via an integrated SaaS offering. Its focus is on smart robotics digitization, smart content management with AI, and helping enable RPA and business processes.Ripcord is based in Hayward, California, and is backed by leading investors Kleiner Perkins Caufield & Byers,Google Ventures, Lux Ventures, Legend Star, and Apple Co-Founder Steve Wozniak.
24M Technologies — 24M Technologies develops energy storage systems for grid and transportation applications. 24M Technologies, Inc. builds energy storage systems for grid and transportation applications. The company was founded in 2010 and is based in Cambridge, Massachusetts.
Tome Biosciences — Tome Biosciences is a biotechnology company that develops programmable gene insertion technology. Using CRISPR, its technologies allow them to insert any genetic sequence of any size at any location into any genome.

Incubate Fund is an independent early-stage venture capital that specializes in providing capital to technology startups at the seed stage. The firm built a portfolio of over 300 companies in Asia, taking 12 companies to public and 20 companies to M&A exit since 2010.

Investment focus

Software, Information Technology, E-Commerce
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

Gatebox — It is a research laboratory beyond dimension" which is researching and developing to realize "a world where you can live with a character". Therefore, Gatebox Co., Ltd. refers to itself as "Gatebox Lab" and conducts research and development beyond dimension in the area of Akihabara day and night. Dreaming that day,coming to meet beyond dimension.
NABLA Mobility — Solving the complexities involved in the "Operation of Fleets" of Mobility and support its evolution and decarbonization
Mjolnir Spaceworks — Mjolnir Spaceworks desings and manufactures state-of-the-art novel space rockets with efficient engines as well as other space equipments.

FFG Venture Business Partners is a large-scale enterprise that offers in traditional regional bank venture capital.

Investment focus

Software, Health Care, Artificial Intelligence
Funding Round, Series A, Seed
Japan, United States

Portfolio highlights

Oxxx — Oxxx is an e-commerce management agency that provides EC site management, planning, and sales of frozen home delivery infant food mogumo.
aiESG — aiESG offers an AI platform that conducts ESG assessments of supply chains and facilitates an in-depth sustainability evaluation.
Josan-shes — Josan shes is web start up that offers nursing service to women and babies.

DG Daiwa Ventures invests in start-up companies with next-generation technology and provides business development support. It is focused on blockchain, xR, AI, security, and BioHealth, as they are likely to be at the foundations of future businesses. In addition to the five core technologies, the fund will also focus on IoT technologies, whichoften overlap or serve as an application layer.

Investment focus

FinTech, Software, Internet
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

Lens — Lens ocuses on supporting corporate activities related to governance, risk management, compliance (GRC), and security.
Zolve — Best neo bank in India offering international banking & financial services online. Apply for a US bank account, credit card & student education loan with Zolve!
Acompany — Acompany provides products and consulting development related to secret computing.

KSP, Inc. is the core business entity responsible for operating the Kanagawa Science Park (KSP) and has accepted the challenge of creating new industries through the support, development, and incubation of venture businesses. We provide a variety of business support services that best meet the needs of venture businesses in each stage of theirbusiness growth, ranging from the processes of startup and growth to public offerings. Several hundreds of new startup companies have been created and nurtured since its foundation. An incubation manager (IM) acts as a coordinator and provides a variety of support services to a venture company to help them successfully launch and develop their new business, such as offering individual consultations and a variety of information or advice. KSP, Inc. is well poised to cope with the varying needs of new ventures for highly sophisticated, specialized tasks by offering a business school, business support center, business matching services, and investment funds.The public sector, such as the Kanagawa prefectural government, Kawasaki city government, and the Development Bank of Japan, Inc., has an equity participation in KSP, thus playing a vital role in the deployment of local industrial development policy.

Investment focus

Biotechnology, Health Care, Medical
Funding Round, Series A, Series B
Japan

Portfolio highlights

3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.

Tsukuba Institute of Research (筑波総研) is an R&D center owned by housing and wood products group Sumitomo Forestry. The facility develops technologies to make more effective use of wood in a wide range of fields.

Investment focus

Medical, Biotechnology, Manufacturing
Series A, Funding Round, Seed
Japan

Portfolio highlights

LIGHTz — LIGHTz delivers a technology transfer and information exchange platform leveraging AI.
Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.
Veneno Technologies — Veneno Technologies engages in the research and development of therapeutic disulfide-rich peptides and contribute to advanced medicine.

Chushin Venture Capital is a venture capital fund established by Kyoto Chuo Shinkin Bank.

Investment focus

Retail, Travel, Home Decor
Series A, Series B
Japan

Portfolio highlights

HOLO BIO — HOLO BIO is a research and technology firm that employs biological breeding techniques to address the food challenges faced by humanity.
RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.
DeepForest Technologies — DeepForest Technologies is an IT firm that offers drone photography, forest information analysis, DF Scanner, and data processing services.

Takeda is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines.

Investment focus

Biotechnology, Health Care, Pharmaceutical
Grant, Funding Round, Corporate Round
United States, Japan, China

Portfolio highlights

Ascentage Pharma — As one of the leading clinical stage biopharmaceutical companies, we develop innovative therapies for global medical needs. Our biotech company is engaged in developing novel approaches for treating cancer.
Crescendo Biologics — Crescendo Biologics is a new Cambridge-based company whose vision is to deliver next-generation antibody therapeutics based on novel class-leading platforms.The focus of the company is on developing platforms that will address key issues in generating high-affinity, soluble, human VH antibody fragments. These are the smallest fragments thatretain antibody binding, and have many desirable properties as potential therapeutics. Crescendo will then utilise these platforms for product development of in-house targets or in partnership with other companies.
Atlanta Community Food Bank — We're on a mission to end hunger in our community. Learn more about how the Atlanta Community Food Bank provides hunger relief to families in need.

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Funding Round
United States, United Kingdom, Israel

Portfolio highlights

Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Degron Therapeutics — Degron Therapeutics is a leading platform company in discovery of molecular glue degraders for cancer treatment.
EvolveImmune Therapeutics — EvolveImmune Therapeutics transforms the discovery and development of novel immunotherapies. By leveraging its proprietary in vivo target discovery platform, EvolveImmune is building a pipeline of novel therapeutic candidates against numerous targets that are expressed on multiple immune cell types. The company’s platform will generatefirst-in-class treatments for unmet needs in oncology and autoimmune diseases.

DISCOVERY, DEVELOPMENT, DEPLOYMENT FOR GLOBAL HEALTH, WITH SCIENCE & BUSINESS ACUMEN

Investment focus

Electronics, Medical Device, Artificial Intelligence
Seed

Portfolio highlights

Swarmer — Swarmer is an AI based mission control center for coordinated drones that acts as Firmware for video streaming, logging and monitoring.
Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.
Neros Technologies — Neros is vertically integrating production of unmanned defense systems in the United States, securing the autonomous supply chain. Are you with us?

Eight Roads has a 50+ year history of investing and partners with game-changing technology and healthcare companies, supporting them as they scale to become global leaders.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, India

Portfolio highlights

Swan — Use Swan's APIs to embed white-labeled banking features like accounts, cards, and IBANs into your workflows and UX.
BlissClub — BlissClub is the community's first women's activewear brand.
Eleos Health — Eleos Health provides AI-powered, highly compliant documentation automation to ease the operational burden on behavioral healthcare providers.

Kyogin Lease & Capital is an investment firm that specializes in the leasing, stock and bond investment and public offering consulting.

Investment focus

Manufacturing, Task Management, Medical
Funding Round, Series A, Series B
Japan

Portfolio highlights

Thinca — Thinca is an IT system planning, development, and operations company that provides a cloud-based CTI (Computer Telephony Integration) hospitality & communication solution for corporate offices.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.

JIC-VGI helps promote innovation and improve its international competitiveness through growth-investments in startup companies. The firm accelerating innovation and helping to solve industrial and social issues by supporting and seeking innovative technologies and new businesses.JIC Venture Growth Investments was established in July 2020 and isbased in Tokyo, Japan.

Investment focus

Information Technology, Software, Financial Services
Series B, Series C, Funding Round
Japan, Singapore, Thailand

Portfolio highlights

Manabie — Manabie is an Education Technology start-up company on a mission to provide a new style of online & offline merged learning around the world. We provide students with everything they need for efficient learning; high-quality learning materials, great learning environments, personal coaches and more! We believe that our new method of learning,integrating online and offline will dramatically innovate the way students learn.
Gaudi Clinical — Gaudi Clinical is a health care firm that engages in regenerative medicine outsourcing and cell processing contract establishments.
Boston Medical Sciences — Boston Medical Sciences conducts research, prevention, and diagnostics procedures to eliminate colorectal cancer deaths.

Sosei CVC is support the creation and growth of life science companies.

Investment focus

Biotechnology, Medical, Pharmaceutical
Funding Round, Series A, Series B
Japan

Portfolio highlights

Junten Bio — JUNTEN BIO is a company is to develop new technologies in the field of regenerative medicine.
Chromocenter — Chromocenter is a next generation biopharmaceuticals Manufacturing company. It uses technologies such as artificial chromosome vectors, mainly for drug discovery such as medical pharmaceuticals
Noile-Immune Biotech — Neurymune Biotech Co., Ltd. is a national cancer research center specializing in the development of cancer immunotherapies based on CAR-T cell therapy and a venture company from Yamaguchi University. They aim to be a leading company responsible for the next generation in the field of cancer immunotherapy.

The Japan Medical Device Development Organization aims to activate Japan's medical innovation and medical device industry, centering on the medical device incubation business, and aim for Japan to become a world leader in this field.Japanese Organization for Medical Device Development is a country of craftsmanship, possesses high technicaland quality control skills, and should be good at producing medical equipment. However, in the medical device field, imports exceed 600 billion yen every year. Japan's “manufacturing” technology has not been fully utilized.

Investment focus

Biotechnology, Laser, Medical
Seed, Series A, Funding Round
Japan, United States

Portfolio highlights

Luxonus — Luxonus is a product development of a new imaging device using optical ultrasonic technology.
Meltin MMI — Meltin MMI is a cyborg-technology company that focuses on biosensors and robotic arms. Meltin has successfully enabled fine finger movements, such as for amputees and participated in Cybathlon 2016 and won the Microsoft Innovation Award.
Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.

Capital Medica Ventures is a venture capital firm based in Tokyo, Japan with a focus on startups in the healthcare industry.Capital Medica Ventures is a venture capital that operates a venture fund specializing in the healthcare field. It is the only healthcare-specialized VC in Japan that can provide 30 medical institutions as a business trialfield.

Investment focus

Medical, Software, Health Care
Seed, Series A, Funding Round
Japan

Portfolio highlights

HCMJ — HCMJ specializes in software development in the medical industry.
Epigno — Epigno provides hospital management systems for medical institutions.
Rehab — Rehab for Japan is developing a special rehabilitation SaaS for day service .

Yokohama Capital as a venture capital firm conducts investment and rehabilitation support for small and medium-sized companies.

Investment focus

Health Care, Artificial Intelligence, Manufacturing
Funding Round, Series A, Series B
Japan

Portfolio highlights

Any — any. develops and offers knowledge sharing tool Qast.
PXP — PXP is a green tech development firm that develops clean energy using next-generation photoelectric conversion elements.
NABLA Mobility — Solving the complexities involved in the "Operation of Fleets" of Mobility and support its evolution and decarbonization

Koki Yabu is Founder, President & CEO at Mobcast inc.

Investment focus

Content, Finance, Data Mining
Angel, Pre-Seed
Japan

Portfolio highlights

Mobcast group — mobcast is a sports entertainment company that operates a mobile entertainment platform for smartphones and feature phones. It supports customers with social game and social media services. The company was founded in 2009 and is based in Tokyo, Japan. Currently, it operates as a subsidiary of mobcast Inc.
SmartApp Japan — Smart Apps is a developer of a blockchain services application designed for smartphones. The company's application uses cryptocurrency technology to offer token issuance, initial coin offering and dApps design support, providing a launchpad for start-up blockchain-related businesses.

THVP is a venture capital corporation for startup innovation. It was established in 2015 and is based in Nagoya, Japan.

Investment focus

Medical, Nursing and Residential Care, Manufacturing
Series A, Seed, Series C
Japan

Portfolio highlights

LIGHTz — LIGHTz delivers a technology transfer and information exchange platform leveraging AI.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
Hakko Holdings — Hakko Holdings is a food-tech company that specializes in producing and manufacturing fermented plant-based food with unique fermentation technology for healthy and sustainable lives.

Chugin Capital Partner is a venture capital firm.

Investment focus

Communities, Health Care, Biotechnology
Seed, Series A, Series B
Japan

Portfolio highlights

ByWill — ByWill creates and distributes environmental value while eventually becoming carbon neutral.
xCARE — xCARE specializes in the development and commercialization phases of the pharmaceutical and medical device industries.
Better Place — Better place vision is to create a world in which kind people can continue to be kind, as well as a society in which people can work in their own way without worrying about money.

NEC Capital Solutions Limited provides financial services in Japan. It's Main Business is Leasing for Information and Communication Equipment, Office Equipment, Industrial Equipment and Installment Sales, Business Loans, Factoring Services, Business Outsourcing and Sales of Used Equipment.

Investment focus

Internet, Manufacturing, Information Technology
Funding Round, Series B, Series A
Japan, United States, Tanzania

Portfolio highlights

GITAI — GITAI is a robotics startup for space development. The company aims to replace astronauts with robots that can work for a long time while being remotely controlled from earth while in low earth orbit space stations to decrease the burden on astronauts, shorten the time it takes to perform work in space, and reduce costs.
Luup — Luup is an Internet Company.
S-Mat — Smartmat is an eco-friendly IoT purchase system for on-demand, no-hassle grocery with cost-effective shipping.

Spiral Capital is a venture capital fund.

Investment focus

Software, Information Technology, Internet
Funding Round, Series B, Series A
Japan, United Kingdom

Portfolio highlights

Bloomo Securities — Bloomo Investment is a software company that specializes in the development of smart and fun investment apps.
HQ — Hq is a consutling firm that works in the area of personnel organization strategy, working style office strategy and software development.
Acompany — Acompany provides products and consulting development related to secret computing.

The Awa Bank provides financial services such as deposits, loans, and foreign exchange transaction.

Investment focus

Software, Automotive, Taxi Service
Series A, Funding Round
Japan

Portfolio highlights

DennoKotsu — Denno Kotsu is a Taxi dispatch system development and provision, taxi company contract dispatch service
Setsuro Tech — Seturotech Co., Ltd. is a biotechnology venture company established on February 22, 2017 by Tatsuya Takemoto (PI: Principal Investigator) of the University of Tokushima as a venture from Tokushima University. In 2015, Takemoto and Masakazu Hashimoto (Osaka University) developed a simple and highly efficient method for producing genetically modified(genome-edited) mice using CRISPR / Cas9, and filed a patent application for the technology. The technology is called fertilized egg electroporation (GEEP method), a technology that introduces molecules required for genome editing by CRISPR into fertilized eggs at high throughput by the power of electricity (electroporation). Using this technology, Seturotech will start from the production and sale of genetically modified mice, and will become a fundamental company providing all genetically modified animals, anticipating the future use of genetically modified animals in industry.

Coral Capital is a seed stage venture capital firm in Japan.

Investment focus

Software, Information Technology, SaaS
Seed, Series A, Series B
Japan, United States

Portfolio highlights

Lens — Lens ocuses on supporting corporate activities related to governance, risk management, compliance (GRC), and security.
CoLab — CoLab is a technology company that provides robotics, artificial intelligence solutions, and business consulting services.
NutmegLabs — NutmegLabs takes care of tourism and leisure by helping with online booking and digitizing the business. It was founded in 2019 and is based in San Francisco, California, United States.

JAIC is Japan's largest independent venture capital firm and has accumulated experience and know-how over a period of 15 years as a pioneer of venture capital investments in Asia. Building on such strengths, they are establishing a globally linked organization that pursues investment opportunities centering on the three regions of Japan, Asia,and the United States.

Investment focus

Medical, Biotechnology, Health Care
Series B, Funding Round, Series C
Japan, United States, China

Portfolio highlights

FacePeer — FacePeer is looking for people who want to challenge at startup.
REGiMMUNE — REGiMMUNE Corporation is a private biopharmaceutical company developing innovative solutions for treating immune disorders caused by nonspecific and/or excessive immune reactions. REGiMMUNE uses its proprietary technology platform, reVax (reverse vaccination), to target immune tolerance against specific disease-causing antigens throughinduction of regulatory T cells (Treg). This technology has potential applications in a number of immune system disorders and diseases including Graft versus Host Disease (GvHD), type 1 diabetes mellitus (T1DM), rheumatoid arthritis (RA), multiple sclerosis (MS) and systemic lupus erythematosus (SLE).Currently, the company has one clinical-stage compound in a Phase I/II trial in the United States (RGI-2001) as a treatment for GvHD associated with hematopoietic stem cell transplantation and has a second product in preclinical development (RGI-3001) as a new treatment for T1DM. In addition, it has a number of well-differentiated compounds in its research-stage pipeline.In healthy individuals, the normal immune system works to protect humans from disease-causing viruses, bacterium, and cancers; or foreign antigens such as peanuts, wheat and tree pollens. Conventional immunosuppressants have several significant side effects associated with long-term administration including risk of infection, toxicity and relapse. Products developed with ReVax technology are expected to reduce or eliminate such side effects as well as reduce long-term treatment.
Integral Geometry Science — Integral Geometry Science is a specialized manufacturer of measuring equipment and signal / image processing software.

TechAccel Ventures is a Seed and Early-Stage Venture Capital firm focused on technology startups in Japan. The firm contributes to the development of the Japanese industry by providing investment and support based on a technical perspective.

Investment focus

Manufacturing, Information Technology, Information Services
Funding Round, Series A, Series B
Japan, United States

Portfolio highlights

SIRU+ — SIRU+ is a startup that enables you to convert consumer purchasing data into nutrients and visualize and quantify consumer shopping trends. Through the app developed by the company, consumers can know their nutrition status. The service “SIRU+ (SIRU+)” is an app that lets you know the nutrition of what you bought by simply registering a super pointcard.
EAGLYS — EAGLYS provides a platform for secure computing and AI.
KOALA Tech — Koala Tech Inc. is an innovative high-tech startup company, whose goal is to pioneer practical applications of the world's first organic semiconductor laser diode that has been realized in the Center for Organic Photonics and Electronics Research (OPERA) at Kyushu University.

The University of Tokyo IPC is a company responsible for expanding the innovation ecosystem of the University of Tokyo. Accelerate global innovation from the University of Tokyo through three activities: start-up support, investment business, and corporate innovation support.It was established as a wholly-owned subsidiary of the University ofTokyo in 2016 with the enforcement of the revised law of the Industrial Competitiveness Enhancement Law, which is the basis law. The investment targets of the Todai IPC are venture companies that utilize the research results and human resources of the University of Tokyo, but they also make FOF (fund of funds) investments in funds managed by some private venture capital companies. In 2019, it started a consortium-type incubation program (University of Tokyo IPC 1stRound) to support the establishment and financing of Tokyo University-related ventures.

Investment focus

Biotechnology, Medical, Manufacturing
Series A, Funding Round, Series B
Japan, United States, United Kingdom

Portfolio highlights

Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
RoboTruck — RoboTruck develops autonomous driving technologies for huge trucks, as well as practical applications.
Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

Global Brain Corporation is a venture capital firm that invests in companies from seed or early to pre-IPO startups. Global Brain has invested in 300+ startups from seed/early to pre-IPO startups and achieved 25 IPOs and 61 M&As as a result of providing hands-on support services and resources to its portfolio startups. Global Brain hasmanaged a pure investment fund as well as multiple corporate venture capital funds partnered together with tier 1 public companies of telecom, real estate development, financial service, beverages, agriculture food, logistics, and electronic devices.

Investment focus

Information Technology, Software, Artificial Intelligence
Series A, Series B, Funding Round
Japan, United States, United Kingdom

Portfolio highlights

10x — 10x provides One-stop service from meal planning to grocery shopping.
Otetsutabi — Otetsutabi is a regional revitalization platform that offers the opportunity for participants to help at accommodations and breweries in rural areas that struggle with seasonal labor shortages. The locals offer transportation expenses and places to stay in return, so participants can travel to the areas with ease.
Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.

Primal Capital, an independent venture capital " incubator bait fund at ", served as the Associate than July 2012 Hiroshi was Sasaki is the venture capital fund that serves as the representative partner. Representative of Sasaki, the seed acceleration program "Incubate Camp" operated by Incubate bait fund is carried out a totalof four times of planning and management than in 2012, They have also engaged in support operations of portfolio companies. - See more at: https://www.crunchbase.com/organization/primal-capital#sthash.m2z1DCbt.dpuf

Investment focus

Software, Information Technology, Internet
Seed, Funding Round, Pre-Seed
Japan, Spain, Switzerland

Portfolio highlights

Hivello — Hivello is a Decentralized Physical Infrastructure Network aggregator. Contribute resources, connect with Web3 protocols, and effortlessly generate passive income.
RemitAid — RemitAid is a fintech company that operates an overseas payment platform for cross-border transactions between companies.
xCARE — xCARE specializes in the development and commercialization phases of the pharmaceutical and medical device industries.

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