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Top 50 Biotechnology Startup Investors in Japan (June 2026)

The most active venture capital funds and angel investors investing in Japan Biotechnology startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in Japan Biotechnology startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Mitsubishi UFJ Capital
VC Fund
18 Japan, United States, Singapore Series A, Series B Information Technology, Software, Health Care $2M–$397M
UntroD Capital
VC Fund
18 Japan, Singapore, Austria Seed, Series A Manufacturing, Biotechnology, Medical $2M–$241M
Fast Track Initiative, Inc.
VC Fund
16 Japan, United States, United Kingdom Series A, Seed, Series B Health Care, Biotechnology, Medical $1.1M–$184M
Osaka University Venture Capital
VC Fund
15 Japan Seed, Series A Biotechnology, Health Care, Manufacturing $7.1M–$142M
ANRI
VC Fund
15 Japan, United States, India Seed, Series A Software, Health Care, Information Technology $1M–$624M
SMBC Venture Capital
VC Fund
14 Japan, United States, Singapore Series A, Series B Information Technology, Health Care, Software $5M–$425M
Keio Innovation Initiative
VC Fund
12 Japan, United Kingdom Series A, Seed Health Care, Medical, Biotechnology $1.5M–$400M
UTEC - The University of Tokyo Edge Capital Partners
VC Fund
12 Japan, United States, India Seed, Series A Health Care, Biotechnology, Medical $3.1M–$85M
JAFCO
VC Fund
11 Japan, United States, Israel Series A, Series B Information Technology, Software, Artificial Intelligence $2.7M–$425M
SBI Investment
VC Fund
9 Japan, United States, South Korea Series B, Series A Information Technology, Software, Financial Services $4.8M–$283M
Real Tech Japan
VC Fund
9 Japan, Singapore, Austria Series A, Seed Manufacturing, Biotechnology, Medical $5M–$241M
Mizuho Capital
VC Fund
9 Japan, United States, China Series A, Series B Information Technology, Software, Internet $2.7M–$850M
Miyako Capital
VC Fund
8 Japan, United States, United Kingdom Series A, Seed, Series B Medical, Biotechnology, Information Technology $5.6M–$3B
DBJ Capital
VC Fund
7 Japan, United States, Australia Series A, Series B Software, Medical, Health Care $4M–$510M
Nissay Capital
VC Fund
7 Japan, United States, Ethiopia Seed, Series A Health Care, Information Technology, Medical $709k–$77M
Japan Science and Technology Agency
VC Fund
6 Japan Series A, Seed Medical, Biotechnology, Manufacturing $1.7M–$255M
Miraidoa
VC Fund
6 Japan, United States, Myanmar Seed, Series A Health Care, Manufacturing, Information Technology $933k–$125M
Nippon Venture Capital
VC Fund
5 Japan, United States Series A, Series B Software, Health Care, Medical $3M–$425M
Senshu Ikeda Capital
VC Fund
5 Japan Seed, Series A Software, Internet, Manufacturing $1.5M–$142M
FFG Venture Business Partners
VC Fund
5 Japan, Indonesia, United States Series A, Seed Software, Health Care, Artificial Intelligence $1.2M–$113M
Fujifilm
VC Fund
4 Japan, United States, China Series A, Corporate Round Biotechnology, Health Care, Medical $1.3M–$1.7B
D3
VC Fund
4 Japan, United States Series A, Seed, Series B Medical, Software, Therapeutics $1.5M–$170M
DG Daiwa Ventures
VC Fund
4 Japan, United States, India Seed, Series A FinTech, Software, Internet $2M–$142M
Incubate Fund
VC Fund
4 Japan, United States, India Seed, Series A Software, Information Technology, E-Commerce $362k–$113M
Remiges Ventures
VC Fund
4 United States, Japan, Canada Series A, Series B, Seed Biotechnology, Medical, Health Care $8.1M–$553M
F-Prime
VC Fund
4 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $9.2M–$130M
Chushin Venture Capital
VC Fund
3 Japan Series A, Seed, Series B Biotechnology, Health Care, Manufacturing $955k–$128M
Eight Roads Ventures
VC Fund
3 United States, China, India Series B, Series A, Series C Software, Health Care, Biotechnology $6.4M–$113M
Angel Bridge
VC Fund
3 Japan Series A, Seed Information Technology, Software, Consulting $746k–$198M
JIC Venture Growth Investments
VC Fund
3 Japan, Singapore, United States Series B, Series C Information Technology, Software, Medical $6.5M–$1.1B
Kyogin Lease & Capital
VC Fund
3 Japan Series A, Series B Medical, Manufacturing, Task Management $6.1M–$340M
Tsukuba Institute of Research
VC Fund
3 Japan Series A, Seed Medical, Biotechnology, Manufacturing $31M–$122M
Sosei CVC
VC Fund
3 Japan Series A, Series B Biotechnology, Medical, Pharmaceutical
KSP
VC Fund
3 Japan Series A, Series B Biotechnology, Health Care, Medical
Takeda Ventures
VC Fund
3 United States, United Kingdom, Israel Series A, Series B Biotechnology, Health Care, Therapeutics $10M–$130M
Takeda
VC Fund
3 United States, Japan, China Grant, Corporate Round Biotechnology, Health Care, Pharmaceutical $5k–$1.4B
Higin Capital
VC Fund
3 Japan Series A, Series B Biotechnology, Medical, Software $1.9M–$184M
Kobe University Capital
VC Fund
2 Japan Series A Apps, Health Care, Health Diagnostics
Koki Yabu
Angel
2 Japan Angel, Pre-Seed Content, Finance, Data Mining
SBI Group
VC Fund
2 Japan, United States, United Kingdom Series A, Series B Financial Services, FinTech, Information Technology
QB Capital
VC Fund
2 Japan, Singapore, United States Seed, Series A Manufacturing, Medical, Biotechnology
Global Brain Corporation
VC Fund
2 Japan, United States, United Kingdom Series A, Series B Information Technology, Software, Artificial Intelligence
Innovation Network Corporation of Japan
VC Fund
2 Japan, United States, United Kingdom Series B, Series A Manufacturing, Software, Robotics
Chugin Capital Partner
VC Fund
2 Japan Series A, Seed, Series B Information Technology, Biotechnology, E-Commerce
Japanese Organization for Medical Device Development
VC Fund
2 Japan, United States Seed, Series A Biotechnology, Laser, Medical $2.1M–$85M
Capital Medica Ventures
VC Fund
2 Japan Seed, Series A Medical, Software, Health Care $14M–$50M
NEC Capital Solutions
VC Fund
2 Japan, United States, Tanzania Series B, Series A Internet, Manufacturing, Information Technology $5.1M–$553M
Media Future
VC Fund
2 Japan Series A Medical, Biotechnology, Genetics $38M–$78M
SPARX Group
VC Fund
2 Japan, United States, United Kingdom Series B, Series A Software, Artificial Intelligence, Information Technology $17M–$425M
Yokohama Capital
VC Fund
2 Japan Series A, Series D Health Care, Information Technology, Artificial Intelligence $38k–$780M
Access all 441 investors in Japan Biotechnology startups.

Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

Mitsubishi UFJ Capital
VC Fund · Tokyo, Tokyo, Japan · 18 investments in Japan Biotechnology startups

Mitsubishi UFJ Capital is a venture capital firm focusing on life science, ICT, and high technology investments.

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Investment focus

  • Industry: Information Technology, Software, Health Care
  • Stage:Series A, Series B
  • Geography: Japan, United States, Singapore

Investor stats

  • Total investments: 462
  • Round size: Series A $2M–$113M; Series B $6.4M–$397M
  • Lead/follow: 5% lead, 95% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2020

Portfolio highlights

  • Sotas — Sotas provides services to chemical trading companies and bridges the gap between raw material producers and consumers.
  • PartnerProp — PartnerProp is a PRM tool with outstanding potential and a wide variety of capabilities that resolves all partner business difficulties.
  • Infobox — Infobox is a sales data platform that includes every detail from market research to creating a list of companies and contacting decision-makers.
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UntroD Capital
VC Fund · Sumida, Tokyo, Japan · 18 investments in Japan Biotechnology startups

UntroD Capital is an R&D-based innovative technology that specializes in social implementation.

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Investment focus

  • Industry: Manufacturing, Biotechnology, Medical
  • Stage:Seed, Series A
  • Geography: Japan, Singapore, Austria

Investor stats

  • Total investments: 119
  • Round size: Seed $2M–$43M; Series A $2.1M–$241M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • CastBio — Castbio specializes in antibody-drug conjugate-based drug discovery research and development. Along with medications, it also creates research reagents, medical equipment, in vitro diagnostic items, and offers drug discovery consulting.
  • Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.
  • Reborna Biosciences — Reborna Biosciences provides research and development in the field of genetic diseases. The company develops therapeutic options for area of unmet medical needs in genetic rare disease. The company's technology enables low-molecular compounds to target ribonucleic acid. The company provides new disease-modifying drugs for patients sufferingfrom rare genetic diseases including spinal muscular atrophy.
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Fast Track Initiative, Inc.
VC Fund · Hongo, Tokyo, Japan · 16 investments in Japan Biotechnology startups

Fast Track Initiative is a venture capital firm with an exclusive focus on life sciences and healthcare services.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Seed, Series B
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 73
  • Round size: Seed $1.2M–$117M; Series A $1.1M–$142M; Series B $7.7M–$184M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: May invest from a new fund soon — raised $1.1B in 2021

Portfolio highlights

  • NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
  • Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.
  • Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.
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Osaka University Venture Capital
VC Fund · Osaka, Osaka, Japan · 15 investments in Japan Biotechnology startups

Osaka University Venture Capital is a venture capital firm that focuses on early-stage ventures in the fields of life innovation, green innovation, and platform technology. The firm was founded in 2014 and based in Osaka, Japan.

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Investment focus

  • Industry: Biotechnology, Health Care, Manufacturing
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 75
  • Round size: Seed $7.1M–$99M; Series A $18M–$142M
  • Lead/follow: 35% lead, 65% follow

Portfolio highlights

  • Ayumo — Ayumo is a research and development company that provides deep learning services with medical insights and AI technology.
  • QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
  • Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.
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ANRI
VC Fund · Tokyo, Tokyo, Japan · 15 investments in Japan Biotechnology startups

ANRI is a Japanese venture capital firm that mainly invests in seed and early-stage startups.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 235
  • Round size: Seed $1M–$94M; Series A $6.1M–$624M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: Likely still investing — raised $102M in 2022

Portfolio highlights

  • Fondi — fondi is a completely new English conversation communication service that allows you to live a virtual communal life with the world.
  • Taian — Taian, which specializes in bridal industry services and software. They also provide ''Concept Marry,'' which allows couples to design invites and seating charts that match their wedding theme, as well as display guest information on Oiwaii.
  • Knowledge Work — Knowledge Work specializes in the development and sales of software for companies.
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SMBC Venture Capital
VC Fund · Tokyo, Tokyo, Japan · 14 investments in Japan Biotechnology startups

Sumitomo Mitsui Banking Corporation (SMBC) and its group companies offer a broad range of financial services centered on banking. They are also engaged in the leasing, securities, credit card, investment, mortgage securitization, venture capital and other credit related businesses. The following lists the activities of SMBC, its subsidiaries andaffiliates in the various business segments.

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Investment focus

  • Industry: Information Technology, Health Care, Software
  • Stage:Series A, Series B
  • Geography: Japan, United States, Singapore

Investor stats

  • Total investments: 485
  • Round size: Series A $5M–$170M; Series B $7.4M–$425M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.
  • Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.
  • Okuma Diamond Device — Ookuma Diamond Device Co., Ltd. | Creating a next-generation semiconductor industry from Japan, driven by the mission to support the decommissioning of Fukushima Daiichi Nuclear Power Plant.
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Keio Innovation Initiative
VC Fund · Tokyo, Tokyo, Japan · 12 investments in Japan Biotechnology startups

Keio Innovation Initiative (KII) is a venture capital established by Keio University. In order to make more effective use of the research results of Keio University, we aim to contribute to the development of society by creating investment for venture companies that utilize research results and creating new industries.The key to thinking aboutJapan's future growth strategy is to utilize advanced research results of the university. In addition to GDP, in addition to GDP, Japan is the world's third largest R & D exporter in R & D expenses, but as the low growth rate shows, it has a problem in investment efficiency in research and development. There are also reports on the entrepreneurial spirit that is indispensable for creating new industries, with the lowest entrepreneurial activity rate among developed countries.

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Investment focus

  • Industry: Health Care, Medical, Biotechnology
  • Stage:Series A, Seed
  • Geography: Japan, United Kingdom

Investor stats

  • Total investments: 76
  • Round size: Seed $1.5M–$213M; Series A $2.3M–$400M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2020

Portfolio highlights

  • ElleThermo — elleThermo aims to implement Semiconductor-Sensitised Thermal Cells (STCs), an energy conversion technology that can generate electricity from unused waste heat above room temperature.
  • Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
  • Nanofiber Quantum Technologies — Discover how NanoQT builds the foundation for scalable quantum computing with nanofiber cavity-QED technology and high-fidelity quantum connectivity.
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UTEC - The University of Tokyo Edge Capital Partners
VC Fund · Tokyo, Tokyo, Japan · 12 investments in Japan Biotechnology startups

UTEC-The University of Tokyo Edge Capital Partners Co., Ltd.. UTEC is a seed/early stage technology focused venture capital firm associated with The University of Tokyo.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 172
  • Round size: Seed $3.1M–$54M; Series A $5.2M–$85M
  • Lead/follow: 37% lead, 63% follow

Portfolio highlights

  • ALGO ARTIS — ALGO ARTIS is a software company that offers optimization in plant operations, tanking, ship allocation plan, and logistics.
  • SUN METALON — SUN METALON aims to create a world where metal products can be produced from local ores. The company was founded in 2021 and is headquartered in Redondo Beach, California.
  • BUGWORKS Research — Bugworks, a clinical stage biopharmaceutical company Harnessing the power of science to develop affordable, accessible, novel therapies against infectious disea
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JAFCO
VC Fund · Tokyo, Tokyo, Japan · 11 investments in Japan Biotechnology startups

Since its founding in 1973, JAFCO has always worked with leading-edge entrepreneurs. The total capital commitments of its investment funds in Japan and overseas have exceeded 1 trillion yen and the number of portfolio IPOs to date has reached over 1,000. In addition to venture investment, JAFCO also carries out buyout investment and commit to thecreations of innovative technologies and services worldwide. As entrepreneurs’ closest partner in bringing their visions to life, JAFCO provides support in areas of HR, marketing/ sales, and back-office operations, in addition to providing financing.

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Investment focus

  • Industry: Information Technology, Software, Artificial Intelligence
  • Stage:Series A, Series B
  • Geography: Japan, United States, Israel

Investor stats

  • Total investments: 252
  • Round size: Series A $2.7M–$255M; Series B $8.3M–$425M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: May invest from a new fund soon — last raise in 2019

Portfolio highlights

  • Caguuu — Caguuu offers high-quality designer furniture at affordable prices, through e-commerce, eliminating middlemen and store operating costs.
  • QREATION — QREATION is a digital intellectual property studio specializing in producing a wide range of popular content that originates primarily from social media platforms. The company focuses on creating high-quality short-form entertainment, including short dramas, comedy sketches, and variety shows.
  • ARCS — ARCS specializes in developing assisted reproductive medical devices using robotics and artificial intelligence technology.
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SBI Investment
VC Fund · Minato, Chiba, Japan · 9 investments in Japan Biotechnology startups

SBI Investment supports the business development and growth of private venture companies through fund investment. It manages and manages venture capital funds under the management philosophy of becoming a leading company responsible for the creation and development of core industries in the 21st century as a "new industry creator".SBIInvestment has invested in a total of 986 companies in the past, of which 169 (17.1% of investment companies) have exited through IPO or M & A.

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Investment focus

  • Industry: Information Technology, Software, Financial Services
  • Stage:Series B, Series A
  • Geography: Japan, United States, South Korea

Investor stats

  • Total investments: 327
  • Round size: Series A $4.8M–$170M; Series B $5.9M–$283M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: May invest from a new fund soon — raised $1.1B in 2020

Portfolio highlights

  • Recho — Recho’s voice AI solutions must offer some unique features. Recho has a mission to "create the future of communication" and provides the VoiceAI platform and its application, Voice Agent.
  • Pliant — Pliant makes the latest generation of corporate credit cards that adapt perfectly to business processes and needs.
  • Captain Fresh — Captain Fresh is a freshwater fish and seafood supply chain platform. Captain Fresh is a B2B marketplace leveraging technology to deliver the fastest harvest-to-retail in the industry. The company focuses on aggregating the fragmented retail demand across the country and linking them to the small fishermen and farmers throughout the Indian coast.The company was founded in 2019 and is based in Bengaluru, India.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

Browse database — It's Free!
Real Tech Japan
VC Fund · Sumida, Tokyo, Japan · 9 investments in Japan Biotechnology startups

Real Tech Japan is a venture capital firm that seeks to invest in innovative R&D technology companies. Realtech Fund is a joint venture between the Ministry of Economy, Trade, and Industry and NEDO (New Energy and Industrial Technology Development Organization). The firm was founded in 2014 and based in Tokyo, Japan.

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Investment focus

  • Industry: Manufacturing, Biotechnology, Medical
  • Stage:Series A, Seed
  • Geography: Japan, Singapore, Austria

Investor stats

  • Total investments: 79
  • Round size: Seed $5M–$43M; Series A $6M–$241M
  • Lead/follow: 41% lead, 59% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
  • Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
  • MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.
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Mizuho Capital
VC Fund · Tokyo, Tokyo, Japan · 9 investments in Japan Biotechnology startups

Mizuho is the venture capital firm affiliated to Mizuho Bank, the second-largest Japanese bank in terms of assets. The firm has headquarters in Tokyo.The firm has ¥49.6 billion JPY under management, focusing on information technology and biotechnology investments. Over 600 Mizuho companies have gone public. According to Nikkei, Mizuho is thefifth-largest venture capital firm in Japan.Mizuho Capital was formed in 2002 by the merger of Fujigin Capital, Tokyo Venture Capital and IBJ Investment. Three firms were subsidiaries of Fuji Bank, Dai-Ichi Kangyo Bank and the Industrial Bank of Japan respectively.

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Investment focus

  • Industry: Information Technology, Software, Internet
  • Stage:Series A, Series B
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 418
  • Round size: Series A $2.7M–$156M; Series B $3.8M–$850M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2020

Portfolio highlights

  • Logiless — Logiless is a cloud type all-in-one software dedicated to net shop. Since both orders and stocks can be managed together in a logical manner, efficiency of operations can be realized at low cost.
  • ARCS — ARCS specializes in developing assisted reproductive medical devices using robotics and artificial intelligence technology.
  • OpenHeart — OpenHeart is a provider of the tactile 3D platform.
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Miyako Capital
VC Fund · Kyoto, Kyoto, Japan · 8 investments in Japan Biotechnology startups

Miyako Capital is the venture capital that manages Kyoto University 2nd Venture Fund (KUVF). The company was founded in 2013 and based in Kyoto & Tokyo, Japan. Investment fields are: 1) Life Science, Biotechnology: Drug creation, regenerative medicine, medical beauty equipment, medical services.2) Agri-Food: Industrialization,agricultural and fishery products growth-promoting technology, specified health food, health food.3) Environment, Energy: Alternative energy, and related technologies.4) IT, Electronics: Web, mobile related devices and application, telecommunication technology, security, consumer and business oriented application, mechatronic, robot.5) New services utilizing state-of-art technology.Investment stages: Primary investment stages are initial-growth stages of seed and early. However, we aim at all growth stages and make investment in post-IPO portfolio companies as well as public companies that are related with Kyoto University.

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Investment focus

  • Industry: Medical, Biotechnology, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 52
  • Round size: Seed $5.6M–$118M; Series A $6.1M–$70M; Series B $99M–$3B
  • Lead/follow: 19% lead, 81% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2019

Portfolio highlights

  • Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
  • VLP Therapeutics — VLP Therapeutics, LLC (VLP) was established in 2012 by seasoned biopharmaceutical veterans with mission to develop innovative medical treatment which transforms traditional vaccine and targeted antibody therapies to address global unmet medical needs. Its vision is to combat the 21st century global public health problems through revolutionary nextgeneration i-αVLP (inserted alpha VLP) Technology. The company is headquartered in Gaithersburg, Maryland
  • XFOREST Therapeutics — xFOREST Therapeutics develops a drug discovery platform that targets RNA structures.
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DBJ Capital
VC Fund · Otemachi, Tokyo, Japan · 7 investments in Japan Biotechnology startups

DBJ Capital Co., Ltd. was founded in June 2010 through the integration of two venture capital firms of the DBJ Group, New Business Investment Co., Ltd. and Intellectual Properties Development & Investment, Inc. We are a wholly-owned subsidiary of Development Bank of Japan Inc.At DBJ Capital, we focus on venture firms which use newtechnologies and business models to grow and compete on the global market, regardless of their industry or scale. To meet the particular needs of each client, we mobilize the entire DBJ Group to arrange the best investment solutions, ranging from growth-spurring equity investment to financing schemes drawing on DBJ's vast networks.We also assist in venture start-ups. Our value enhancement team provides the kind of comprehensive, hands-on support needed to commercialize outstanding intellectual property and technologies developed by firms, research labs, and universities, and to carve out a place for them in the market.DBJ Capital will continue to play in a part in Japan's economic revival - by helping the firms we invest in to grow, and by encouraging the creation of new industries in Japan.

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Investment focus

  • Industry: Software, Medical, Health Care
  • Stage:Series A, Series B
  • Geography: Japan, United States, Australia

Investor stats

  • Total investments: 145
  • Round size: Series A $4M–$283M; Series B $6.9M–$510M
  • Lead/follow: 17% lead, 83% follow

Portfolio highlights

  • Reject — Reject is an esports firm that focuses on management of its team REJECT, players, apparel business, and event management services.
  • Linqmed — Linqmed is a pharmaceutical company that specializes in the research and development of radiopharmaceuticals for cancer treatment.
  • Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.
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Nissay Capital
VC Fund · Tokyo, Tokyo, Japan · 7 investments in Japan Biotechnology startups

Nissay Capital is a venture capital Company specializing in seed, start-up, growth capital, middle stage, and later stage investment.

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Investment focus

  • Industry: Health Care, Information Technology, Medical
  • Stage:Seed, Series A
  • Geography: Japan, United States, Ethiopia

Investor stats

  • Total investments: 223
  • Round size: Seed $709k–$43M; Series A $2.7M–$77M
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Todoker — Todoker is a baggage delivery convenient service providing company.
  • CREO Bioscience — Cleo Bioscience is a Biotechnology company.
  • Fabric Tokyo — FABRIC TOKYO is a Japanese startup provides a direct-to-consumer custom-made apparel brand. (former-company name Lifestyle Design Co., Ltd.). It enables customers to save their sizes, idea fabrics, and favorite designs, allowing them to make their original clothing later.FABRIC TOKYO was founded in 2012 by Yuichiro Mori and is based in Tokyo,Japan.
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Japan Science and Technology Agency
VC Fund · Tokyo, Tokyo, Japan · 6 investments in Japan Biotechnology startups

Japan Science and Technology Agency is an integrated organization of science and technology that implements science and technology policy in Japan.  It handles many projects, including the government’s Science and Technology Basic Plan and knowledge creation. The European Sustainability School ESSSR is the owner of Japan Science and TechnologyAgency.Japan Science and Technology Agency undertakes its task in a comprehensive manner. It also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.Japan Science and Technology Agency is headquartered in Tokyo, Japan.

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Investment focus

  • Industry: Medical, Biotechnology, Manufacturing
  • Stage:Series A, Seed
  • Geography: Japan

Investor stats

  • Total investments: 40
  • Round size: Seed $1.7M–$50M; Series A $3.1M–$255M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
  • Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
  • Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
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Miraidoa
VC Fund · Kyoto, Kyoto, Japan · 6 investments in Japan Biotechnology startups

Future Venture Capital Co., Ltd. is a venture capital firm specializing in early stage investment. The firm invests in diversified investment in a broad range of industrial sectors. It seeks to invest in Japan. The firm prefers to be the lead investor in its portfolio companies. Future Venture Capital Co., Ltd. was founded in 1998 and is based inKyoto, Japan with offices in Tokyo, Aomori, Iwate, Yamagata, Kanazawa, Mie, Sakai, Kobe, and Ehime.

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Investment focus

  • Industry: Health Care, Manufacturing, Information Technology
  • Stage:Seed, Series A
  • Geography: Japan, United States, Myanmar

Investor stats

  • Total investments: 140
  • Round size: Seed $933k–$33M; Series A $2.5M–$125M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: May invest from a new fund soon — raised $36M in 2020

Portfolio highlights

  • Tear Exo — Tear Exo is a biotechnology research company that produces and sells liquid biopsy using materials for molecular recognition.
  • TelaAxon — TelaAxon develops artificial intelligence technology for sustainable operations, enhancing human-AI coexistence, safety, and wellness.
  • Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
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Nippon Venture Capital
VC Fund · Tokyo, Tokyo, Japan · 5 investments in Japan Biotechnology startups

Nippon Venture Capital ("NVCC"), established in 1996 as one of the few largest Japanese independent venture capital firms, is destined to undertake the unprecedented task of providing full-range venture capital services in cooperation with major Japanese business leaders and leading companies, which have supported and nurtured various newbusinesses on their own, as well as proactively developing new venture enterprises.

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Investment focus

  • Industry: Software, Health Care, Medical
  • Stage:Series A, Series B
  • Geography: Japan, United States

Investor stats

  • Total investments: 156
  • Round size: Series A $3M–$85M; Series B $8.2M–$425M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely still investing — raised $278M in 2023

Portfolio highlights

  • Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
  • Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
  • Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.
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Senshu Ikeda Capital
VC Fund · Osaka, Osaka, Japan · 5 investments in Japan Biotechnology startups

Senshu Ikeda Capital offers financial consultancy services.

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Investment focus

  • Industry: Software, Internet, Manufacturing
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 61
  • Round size: Seed $1.5M–$61M; Series A $1.9M–$142M
  • Lead/follow: 5% lead, 95% follow
  • Last fund: May invest from a new fund soon — raised $177M in 2019

Portfolio highlights

  • Sagri — Sagri is developing agriculture software for experienced farmers.
  • Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.
  • Rehabilitation 3.0 — Rehabilitation 3.0 focuses on a preventive medical system that provides AI assessment and tracking on health, exercise, mood, and wellness.
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FFG Venture Business Partners
VC Fund · Fukuoka, Fukuoka, Japan · 5 investments in Japan Biotechnology startups

FFG Venture Business Partners is a large-scale enterprise that offers in traditional regional bank venture capital.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Series A, Seed
  • Geography: Japan, Indonesia, United States

Investor stats

  • Total investments: 72
  • Round size: Seed $5.7M–$69M; Series A $1.2M–$113M
  • Lead/follow: 10% lead, 90% follow
  • Last fund: May invest from a new fund soon — raised $691M in 2020

Portfolio highlights

  • InsightX — InsightX is a technology platform focused on empowering businesses by simplifying complex processes and enabling smarter, more personalized user experiences.
  • ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .
  • Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.
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Fujifilm
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups

Fujifilm develops and sells consumer products and business products related to photography. Fujifilm Holdings Corporation is a Japanese multinational photography and imaging company. The company serves various industries, including medical, graphic arts, optics, enterprise storage, motion picture, and photography.The company’s consumer productsare categorized as digital cameras and accessories, film photography, Instax photography, and binoculars. Its business products are categorized as medical systems, Fujinon endoscopy, microfilm, data storage, graphic arts and printing, professional video, optical devices, specialty chemicals, printing imaging colorants, and more. Color films, digital cameras, photofinishing equipment, color papers, photofinishing chemicals, medical imaging equipment, graphic arts equipment and materials, flat panel displays, and photocopiers and printers are some products developed by Fujifilm USA.Fujifilm USA is based in Minato-ku, Tokyo, Japan.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Corporate Round
  • Geography: Japan, United States, China

Investor stats

  • Total investments: 25
  • Round size: Series A $15M–$425M; Corporate Round $1.3M–$1.7B
  • Lead/follow: 28% lead, 72% follow

Portfolio highlights

  • Ripcord — Ripcord is a robotics company that combines hardware and software robotics via an integrated SaaS offering. Its focus is on smart robotics digitization, smart content management with AI, and helping enable RPA and business processes.Ripcord is based in Hayward, California, and is backed by leading investors Kleiner Perkins Caufield & Byers,Google Ventures, Lux Ventures, Legend Star, and Apple Co-Founder Steve Wozniak.
  • Rapidus — Rapidus is an Electronic component research, development, design, production, and sales that includes semiconductor elements and integrated circuits. Environmentally friendly, energy-saving semiconductors and semiconductor manufacturing technology are being researched and developed. Human resource development and training for the semiconductorsector.
  • VALANX Biotech — VALANX Biotech is a site-specific protein conjugation platform to enable fast and cost efficient protein-drug-conjugates development.
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D3
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups

DISCOVERY, DEVELOPMENT, DEPLOYMENT FOR GLOBAL HEALTH, WITH SCIENCE & BUSINESS ACUMEN

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Investment focus

  • Industry: Medical, Software, Therapeutics
  • Stage:Series A, Seed, Series B
  • Geography: Japan, United States

Investor stats

  • Total investments: 10
  • Round size: Series A $1.5M–$170M
  • Lead/follow: 60% lead, 40% follow

Portfolio highlights

  • Neumo — Neumo is a musical education-based firm that offers pitch measurement courses, programs, consulting, and tests.
  • RevolKa — RevolKa manufactures bio-products pharmaceuticals intended to serve the healthcare sector.
  • Neros Technologies — Neros is vertically integrating production of unmanned defense systems in the United States, securing the autonomous supply chain. Are you with us?
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DG Daiwa Ventures
VC Fund · Marunouchi, Tokyo, Japan · 4 investments in Japan Biotechnology startups

DG Daiwa Ventures invests in start-up companies with next-generation technology and provides business development support. It is focused on blockchain, xR, AI, security, and BioHealth, as they are likely to be at the foundations of future businesses. In addition to the five core technologies, the fund will also focus on IoT technologies, whichoften overlap or serve as an application layer.

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Investment focus

  • Industry: FinTech, Software, Internet
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 63
  • Round size: Seed $2M–$26M; Series A $4M–$142M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • digzyme — Digzyme is a research and development platform for creating, discovering, and evaluating new enzyme-catalyzed reactions by bioinformatics.
  • Zehitomo — Zehitomo is an Japanese online platform that enables user to hire local service professionals, from photographers to personal trainers.
  • MyDearest — MyDearest is a Full dive product planning and development company
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Incubate Fund
VC Fund · Tokyo, Tokyo, Japan · 4 investments in Japan Biotechnology startups

Incubate Fund is an independent early-stage venture capital that specializes in providing capital to technology startups at the seed stage. The firm built a portfolio of over 300 companies in Asia, taking 12 companies to public and 20 companies to M&A exit since 2010.

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Investment focus

  • Industry: Software, Information Technology, E-Commerce
  • Stage:Seed, Series A
  • Geography: Japan, United States, India

Investor stats

  • Total investments: 269
  • Round size: Seed $362k–$46M; Series A $5.2M–$113M
  • Lead/follow: 23% lead, 77% follow
  • Last fund: Likely still investing — raised $2.4B in 2021

Portfolio highlights

  • Letara — Letara operates a space technology platform with the intention to serve a logistics network covering the solar system. The company produces hybrid propulsion engines for small spacecraft, promoting groundbreaking advances in space propulsion with high thrust, safe, and inexpensive propulsion system technology.
  • Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
  • Black Cat Carnival — Black Cat Carnival Inc. is a communication service development company.
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Remiges Ventures
VC Fund · Cambridge, Massachusetts, United States · 4 investments in Japan Biotechnology startups

Remiges Ventures is a venture capital firm that focuses on groups and businesses in the Japanese academia and pharmaceutical industry.

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Investment focus

  • Industry: Biotechnology, Medical, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, Japan, Canada

Investor stats

  • Total investments: 24
  • Round size: Seed $10M–$42M; Series A $8.1M–$85M; Series B $8.2M–$553M
  • Lead/follow: 63% lead, 37% follow
  • Last fund: May invest from a new fund soon — raised $95M in 2019

Portfolio highlights

  • Kupando — Kupando is a biopharmaceutical company that develops agonists to stimulates innate immunity.
  • Glycomine — We are developing a PMM2-CDG substrate replacement therapy. GLM101 is a mannose-1 phosphate treatment.
  • Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.
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F-Prime
VC Fund · Cambridge, Massachusetts, United States · 4 investments in Japan Biotechnology startups

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 410
  • Round size: Series A $9.2M–$87M; Series B $16M–$130M; Series C $22M–$115M
  • Lead/follow: 27% lead, 73% follow

Portfolio highlights

  • SILQ — Bringing visibility to brands by customizing sourcing and shipping on everything that you need for your business.
  • Deal Engine — Deal Engine is a travel solutions software company that reduces corporate travel expenditure ensuring saving on a flight itinerary.
  • RightHand Robotics — RightHand Robotics offers advanced robotic piece-picking technology for efficient and predictable order fulfillment. Contact us today to learn how.
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Chushin Venture Capital
VC Fund · Kyoto, Kyoto, Japan · 3 investments in Japan Biotechnology startups

Chushin Venture Capital is a venture capital fund established by Kyoto Chuo Shinkin Bank.

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Investment focus

  • Industry: Biotechnology, Health Care, Manufacturing
  • Stage:Series A, Seed, Series B
  • Geography: Japan

Investor stats

  • Total investments: 10
  • Round size: Series A $955k–$128M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Nexta — Nexta manufactures site, issues such as analog management, personalization of operations & labor shortages are becoming more serious.
  • Cizucu — Cizucu is a stock photo community that helps creators and brands to create photos.
  • DeepForest Technologies — DeepForest Technologies is an IT firm that offers drone photography, forest information analysis, DF Scanner, and data processing services.
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Eight Roads Ventures
VC Fund · London, England, United Kingdom · 3 investments in Japan Biotechnology startups

Eight Roads has a 50+ year history of investing and partners with game-changing technology and healthcare companies, supporting them as they scale to become global leaders.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, India

Investor stats

  • Total investments: 354
  • Round size: Series A $6.4M–$62M; Series B $8M–$85M; Series C $13M–$113M
  • Lead/follow: 42% lead, 58% follow
  • Last fund: Likely still investing — raised $350M in 2022

Portfolio highlights

  • JIFFYAI — Transform client engagement with AI solutions for Wealth Management. Deliver personalized experiences, streamline workflows, and scale meaningful interactions.
  • StashAway — StashAway is a MAS-licensed investment platform in Singapore that's designed for portfolio and wealth management for all at low fees.
  • Securonix — Explore Securonix for comprehensive cybersecurity across SIEM, TDIR, UEBA, and SOAR on a scalable cloud platform. Proven effectiveness with top customer ratings.
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Angel Bridge
VC Fund · Tokyo, Tokyo, Japan · 3 investments in Japan Biotechnology startups

Angel Bridge is a angel investor groups in Japan and provide high quality and abundant funds to excellent companies.

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Investment focus

  • Industry: Information Technology, Software, Consulting
  • Stage:Series A, Seed
  • Geography: Japan

Investor stats

  • Total investments: 55
  • Round size: Seed $2.2M–$113M; Series A $746k–$198M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: May invest from a new fund soon — raised $152M in 2019

Portfolio highlights

  • Emole — Emole is a platform that connects content creators with viewers through short drama content, offering a variety of engaging stories.
  • Loglass — Loglass offers corporate intelligence to enhance business management.
  • GenerativeX — GenerativeX provides AI app development, consulting, and generative model development.
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JIC Venture Growth Investments
VC Fund · Marunouchi, Tokyo, Japan · 3 investments in Japan Biotechnology startups

JIC-VGI helps promote innovation and improve its international competitiveness through growth-investments in startup companies. The firm accelerating innovation and helping to solve industrial and social issues by supporting and seeking innovative technologies and new businesses.JIC Venture Growth Investments was established in July 2020 and isbased in Tokyo, Japan.

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Investment focus

  • Industry: Information Technology, Software, Medical
  • Stage:Series B, Series C
  • Geography: Japan, Singapore, United States

Investor stats

  • Total investments: 76
  • Round size: Series B $6.5M–$1.1B; Series C $11M–$411M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • KOMPEITO — Office de Yasai is an online platform that enables users to order and get vegetables delivered to their offices. The platform’s operations are based in Tokyo, Japan.
  • bitkey — Bitkey is a company provides its own key technology.
  • Ark Edge Space — Ark Edge Space provides design, manufacturing & operational services for micro-satellites along with software solutions and consulting.
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Kyogin Lease & Capital
VC Fund · Kyoto, Kyoto, Japan · 3 investments in Japan Biotechnology startups

Kyogin Lease & Capital is an investment firm that specializes in the leasing, stock and bond investment and public offering consulting.

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Investment focus

  • Industry: Medical, Manufacturing, Task Management
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 28
  • Round size: Series A $6.1M–$57M; Series B $38M–$340M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • KOMPEITO — Office de Yasai is an online platform that enables users to order and get vegetables delivered to their offices. The platform’s operations are based in Tokyo, Japan.
  • Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.
  • Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.
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Tsukuba Institute of Research
VC Fund · Ibaraki, Osaka, Japan · 3 investments in Japan Biotechnology startups

Tsukuba Institute of Research (筑波総研) is an R&D center owned by housing and wood products group Sumitomo Forestry. The facility develops technologies to make more effective use of wood in a wide range of fields.

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Investment focus

  • Industry: Medical, Biotechnology, Manufacturing
  • Stage:Series A, Seed
  • Geography: Japan

Investor stats

  • Total investments: 7
  • Round size: Series A $31M–$122M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • LIGHTz — LIGHTz delivers a technology transfer and information exchange platform leveraging AI.
  • Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.
  • Veneno Technologies — Veneno Technologies engages in the research and development of therapeutic disulfide-rich peptides and contribute to advanced medicine.
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Sosei CVC
VC Fund · Tokyo, Tokyo, Japan · 3 investments in Japan Biotechnology startups

Sosei CVC is support the creation and growth of life science companies.

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Investment focus

  • Industry: Biotechnology, Medical, Pharmaceutical
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 7
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Junten Bio — JUNTEN BIO is a company is to develop new technologies in the field of regenerative medicine.
  • Chromocenter — Chromocenter is a next generation biopharmaceuticals Manufacturing company. It uses technologies such as artificial chromosome vectors, mainly for drug discovery such as medical pharmaceuticals
  • Noile-Immune Biotech — Neurymune Biotech Co., Ltd. is a national cancer research center specializing in the development of cancer immunotherapies based on CAR-T cell therapy and a venture company from Yamaguchi University. They aim to be a leading company responsible for the next generation in the field of cancer immunotherapy.
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KSP
VC Fund · Kawasaki, Kanagawa, Japan · 3 investments in Japan Biotechnology startups

KSP, Inc. is the core business entity responsible for operating the Kanagawa Science Park (KSP) and has accepted the challenge of creating new industries through the support, development, and incubation of venture businesses. We provide a variety of business support services that best meet the needs of venture businesses in each stage of theirbusiness growth, ranging from the processes of startup and growth to public offerings. Several hundreds of new startup companies have been created and nurtured since its foundation. An incubation manager (IM) acts as a coordinator and provides a variety of support services to a venture company to help them successfully launch and develop their new business, such as offering individual consultations and a variety of information or advice. KSP, Inc. is well poised to cope with the varying needs of new ventures for highly sophisticated, specialized tasks by offering a business school, business support center, business matching services, and investment funds.The public sector, such as the Kanagawa prefectural government, Kawasaki city government, and the Development Bank of Japan, Inc., has an equity participation in KSP, thus playing a vital role in the deployment of local industrial development policy.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 36
  • Lead/follow: no public data

Portfolio highlights

  • 3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
  • THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
  • Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.
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Takeda Ventures
VC Fund · San Diego, California, United States · 3 investments in Japan Biotechnology startups

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 103
  • Round size: Series A $10M–$58M; Series B $20M–$130M
  • Lead/follow: 18% lead, 82% follow

Portfolio highlights

  • Degron Therapeutics — Degron Therapeutics is a leading platform company in discovery of molecular glue degraders for cancer treatment.
  • Accipiter Biosciences — Accipiter Biosciences is a biotechnology company.
  • Harness Therapeutics — Transine Therapeutics is a private biotechnology company focused on the development of a novel class of therapeutic RNAs that can upregulate protein expression with an unprecedented level of control and specificity: the SINEUPs®. The company's pioneering technology is expected to offer an entirely unique mechanism of action for currentlyhard-to-treat diseases by massively extending the druggable proteome and allowing it to address diseases that have been beyond the reach of small molecules, conventional biologics, or gene therapies.
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Takeda
VC Fund · Osaka, Osaka, Japan · 3 investments in Japan Biotechnology startups

Takeda is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Grant, Corporate Round
  • Geography: United States, Japan, China

Investor stats

  • Total investments: 53
  • Round size: Grant $5k–$35k; Corporate Round $52M–$1.4B
  • Lead/follow: 62% lead, 38% follow

Portfolio highlights

  • Ascentage Pharma — As one of the leading clinical stage biopharmaceutical companies, we develop innovative therapies for global medical needs. Our biotech company is engaged in developing novel approaches for treating cancer.
  • Beacon Biosignals — AI + EEG to change the way patients are treated for disorders of the brain.
  • Crescendo Biologics — Crescendo Biologics is a new Cambridge-based company whose vision is to deliver next-generation antibody therapeutics based on novel class-leading platforms.The focus of the company is on developing platforms that will address key issues in generating high-affinity, soluble, human VH antibody fragments. These are the smallest fragments thatretain antibody binding, and have many desirable properties as potential therapeutics. Crescendo will then utilise these platforms for product development of in-house targets or in partnership with other companies.
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Higin Capital
VC Fund · Kumamoto, Kumamoto, Japan · 3 investments in Japan Biotechnology startups

Higegin Capital is a venture capital firm.

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Investment focus

  • Industry: Biotechnology, Medical, Software
  • Stage:Series A, Series B
  • Geography: Japan

Investor stats

  • Total investments: 22
  • Round size: Series A $1.9M–$184M; Series B $3.8M–$170M
  • Lead/follow: 0% lead, 100% follow
  • Last fund: May invest from a new fund soon — raised $137M in 2020

Portfolio highlights

  • Molmir — Molmir is a biotech company that conducts research and develops treatments for intractable diseases based on sensing technology.
  • Photo Electron Soul — Photo electron Soul mission is to innovate the world of "seeing (fine observation)" and "creating (fine processing)" through the development of photocathode electron beam technology. The photocathode electron beam technology developed by our company will produce next generation electron beams with high performance andversatility (pulse structure, low dispersion, large current). By renewing the electron beam, which is a key device for industrial equipment such as electron microscopes, semiconductor device manufacturing / inspection equipment, and metal 3D printers, it is possible to realize fine observation, fine processing, high throughput, etc. Breakthroughs in a wide range of fields such as science, materials, and electronics.
  • Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.
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Kobe University Capital
VC Fund · Kobe, Kyoto, Japan · 2 investments in Japan Biotechnology startups

Kobe University Capital is create new indstry academia cllabration and technology transfer models.

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Investment focus

  • Industry: Apps, Health Care, Health Diagnostics
  • Stage:Series A
  • Geography: Japan

Investor stats

  • Total investments: 7
  • Lead/follow: no public data

Portfolio highlights

  • Pittan — PITTAN is a health tech startup that focuses on the development of high-speed analytical equipment for use in the healthcare industry. The company's primary service is to analyze the internal status of an individual's body to promote beautiful and healthy skin. This is achieved through the application of analytical chemistry.PITTAN's services are designed to provide insights into the body's health, which can be used to inform personal care and wellness decisions.
  • TelaAxon — TelaAxon develops artificial intelligence technology for sustainable operations, enhancing human-AI coexistence, safety, and wellness.
  • Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.
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Koki Yabu
Angel · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Koki Yabu is Founder, President & CEO at Mobcast inc.

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Investment focus

  • Industry: Content, Finance, Data Mining
  • Stage:Angel, Pre-Seed
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Lead/follow: no public data

Portfolio highlights

  • Mobcast group — mobcast is a sports entertainment company that operates a mobile entertainment platform for smartphones and feature phones. It supports customers with social game and social media services. The company was founded in 2009 and is based in Tokyo, Japan. Currently, it operates as a subsidiary of mobcast Inc.
  • SmartApp Japan — Smart Apps is a developer of a blockchain services application designed for smartphones. The company's application uses cryptocurrency technology to offer token issuance, initial coin offering and dApps design support, providing a launchpad for start-up blockchain-related businesses.
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SBI Group
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

SBI Group aims to become a corporate entity that provides a variety of one-stop financial services over the Internet now that two major events, the Financial Big Bang resulting from deregulation, and the Internet Revolution resulting from IT innovation, have radically transformed the financial industry.

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Investment focus

  • Industry: Financial Services, FinTech, Information Technology
  • Stage:Series A, Series B
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 120
  • Lead/follow: no public data

Portfolio highlights

  • Kigen — Kigen provides technologies for enabling mobile communications for your devices. From SIM to eSIM and RSP, discover our products.
  • Digift — Security Token DEX: Bridging traditional finance and DeFi.
  • Seal Security — Streamline your open source vulnerability remediation without introducing the risk of breaking changes. Say goodbye to alert fatigue and start patching with Seal Security.
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QB Capital
VC Fund · Fukuoka, Fukuoka, Japan · 2 investments in Japan Biotechnology startups

QB Capital is make equity investments in venture companies.

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Investment focus

  • Industry: Manufacturing, Medical, Biotechnology
  • Stage:Seed, Series A
  • Geography: Japan, Singapore, United States

Investor stats

  • Total investments: 49
  • Lead/follow: no public data

Portfolio highlights

  • Alumnote — The alumni association management software developed by Alumnote allows schools to manage their alumni associations online. The focus of the company is to undertake loyalty building and marketing for potential donors such as graduates and provides digital tools, and supports the execution of donation acquisition.
  • Equmenopolis — Equmenopolis is an information services company that specializes in conversational AI agent platforms and application developments.
  • Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.
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Global Brain Corporation
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups, 69 in the past 12 months

Global Brain Corporation is a venture capital firm that invests in companies from seed or early to pre-IPO startups. Global Brain has invested in 300+ startups from seed/early to pre-IPO startups and achieved 25 IPOs and 61 M&As as a result of providing hands-on support services and resources to its portfolio startups. Global Brain hasmanaged a pure investment fund as well as multiple corporate venture capital funds partnered together with tier 1 public companies of telecom, real estate development, financial service, beverages, agriculture food, logistics, and electronic devices.

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Investment focus

  • Industry: Information Technology, Software, Artificial Intelligence
  • Stage:Series A, Series B
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 457
  • Lead/follow: no public data

Portfolio highlights

  • Wiom — Provides affordable and unlimited Internet to Middle and lower middle income households
  • HIVED — Looking for a greener, cheaper and better way to send your parcels? All parcels tracked and insured. Same-day, next-day and other options. Contact us today.
  • Things — Things offer product development and various information such as CAD, drawings, parts configuration, and price information.
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Innovation Network Corporation of Japan
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Innovation Network Corporation of Japan (INCJ) is a public-private partnership aimed at promoting innovation and enhancing value.Leveraging the rich history of Japanese technological prowess, INCJ aims to provide financial, technological and management support in order to promote the creation of next-generation businesses through “openinnovation,” or the flow of technology and expertise beyond the boundaries of existing organizational structures.INCJ will draw on funding as well as management and technological expertise from the public and private sectors. INCJ is actively reviewing various investment opportunities in areas of green energy, electronics, IT and biotechnology to infrastructure-related sectors such as water supply. Each investment will be thoroughly vetted to ensure it meets the exacting standards of INCJ's Innovation Network Committee, which will make the final investment decisions.INCJ is capitalized at 280 billion yen, with the Japanese government injecting 266 billion yen and 26 private corporations (refer to details in Appendix below) providing a further 14 billion yen. The government will also provide guarantees up to a total of 1,800 billion yen for INCJ investments, giving it an investment capability of approximately 2,000 billion yen. INCJ will be established for a period of 15 years.

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Investment focus

  • Industry: Manufacturing, Software, Robotics
  • Stage:Series B, Series A
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 123
  • Lead/follow: no public data

Portfolio highlights

  • Cloudian — Cloudian provides exabyte-scale storage for your capacity-intensive workloads: S3-compatible storage for on-prem, hybrid cloud, and multi-cloud.
  • Seajacks — Cadeler is a global leader in offshore wind farm construction, maintenance, and decommissioning.
  • Vehicle Energy Japan — Vehicle Energy Japan specializes in development, manufacturing and sales of automotive lithium-ion batteries.
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Chugin Capital Partner
VC Fund · Okayama, Okayama, Japan · 2 investments in Japan Biotechnology startups

Chugin Capital Partner is a venture capital firm that invests in startups and business succession.

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Investment focus

  • Industry: Information Technology, Biotechnology, E-Commerce
  • Stage:Series A, Seed, Series B
  • Geography: Japan

Investor stats

  • Total investments: 18
  • Lead/follow: no public data

Portfolio highlights

  • Experisus — Experisus provides Website production, development and management, and software.
  • Waku — Waku is a manufacturing company that specializes in the research and development of organic fertilizers for the agriculture industry.
  • Zip Infrastructure — Inquiry : https://docs.google.com/forms/d/e/1FAIpQLSfDmxd1TpPP331TY4VoRsvn0yWX3Ca5Jd-bfBiuPwvpD2SKtA/viewform
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Japanese Organization for Medical Device Development
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

The Japan Medical Device Development Organization aims to activate Japan's medical innovation and medical device industry, centering on the medical device incubation business, and aim for Japan to become a world leader in this field.Japanese Organization for Medical Device Development is a country of craftsmanship, possesses high technicaland quality control skills, and should be good at producing medical equipment. However, in the medical device field, imports exceed 600 billion yen every year. Japan's “manufacturing” technology has not been fully utilized.

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Investment focus

  • Industry: Biotechnology, Laser, Medical
  • Stage:Seed, Series A
  • Geography: Japan, United States

Investor stats

  • Total investments: 6
  • Round size: Series A $2.1M–$85M
  • Lead/follow: 33% lead, 67% follow

Portfolio highlights

  • Luxonus — Luxonus is a product development of a new imaging device using optical ultrasonic technology.
  • Meltin MMI — Meltin MMI is a cyborg-technology company that focuses on biosensors and robotic arms. Meltin has successfully enabled fine finger movements, such as for amputees and participated in Cybathlon 2016 and won the Microsoft Innovation Award.
  • Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
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Capital Medica Ventures
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Capital Medica Ventures is a venture capital firm based in Tokyo, Japan with a focus on startups in the healthcare industry.Capital Medica Ventures is a venture capital that operates a venture fund specializing in the healthcare field. It is the only healthcare-specialized VC in Japan that can provide 30 medical institutions as a business trialfield.

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Investment focus

  • Industry: Medical, Software, Health Care
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 9
  • Round size: Seed $14M–$17M; Series A $23M–$50M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • HCMJ — HCMJ specializes in software development in the medical industry.
  • Epigno — Epigno provides hospital management systems for medical institutions.
  • Rehab — Rehab for Japan is developing a special rehabilitation SaaS for day service .
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NEC Capital Solutions
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

NEC Capital Solutions Limited provides financial services in Japan. It's Main Business is Leasing for Information and Communication Equipment, Office Equipment, Industrial Equipment and Installment Sales, Business Loans, Factoring Services, Business Outsourcing and Sales of Used Equipment.

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Investment focus

  • Industry: Internet, Manufacturing, Information Technology
  • Stage:Series B, Series A
  • Geography: Japan, United States, Tanzania

Investor stats

  • Total investments: 56
  • Round size: Series A $5.1M–$142M; Series B $7.1M–$553M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • GITAI — GITAI is a robotics startup for space development. The company aims to replace astronauts with robots that can work for a long time while being remotely controlled from earth while in low earth orbit space stations to decrease the burden on astronauts, shorten the time it takes to perform work in space, and reduce costs.
  • Luup — Luup is an Internet Company.
  • Idea Record — Idea;record specializes in web marketing, cloud services, and ICT solutions. They are creating a SaaS firm that will generate revenue. GATE is a SaaS that solves challenges for restaurant businesses and solutions to multiple problems faced by stores.
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Media Future
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

Media Future is a group of communication technology professionals that works on connecting feelings and thoughts. The Tokyo, Tokyo-based company was established in 2013.

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Investment focus

  • Industry: Medical, Biotechnology, Genetics
  • Stage:Series A
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Round size: Series A $38M–$78M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
  • HekaBio — HekaBio connects world-leading healthcare innovations to unmet medical needs in the Asia Pacific, with broad category development expertise in pharma, medical device, in-vitro diagnostics, digital health, and cell & gene therapies.
  • Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).
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SPARX Group
VC Fund · Tokyo, Tokyo, Japan · 2 investments in Japan Biotechnology startups

SPARX Group Co., Ltd. is an independent Asia-based equity and credit asset management services and Asian fund financial specialist with offices in Tokyo, Hong Kong and Seoul for global institutional and individual investors, including financial advisors and financial planners, with alternative strategies (including activist, short-enabled, private equity and quantitative and fund-of-funds) and mutual funds (through SPARX Asia Funds such as SPARX Asia Pacific Opportunities Fund, SPARX Asia Pacific Equity Income Fund, SPARX Japan Smaller Companies Fund and SPARX Japan Fund) managed or sub-advised by SPARX Asset Management Co. Ltd., SPARX Asia Investment Advisors Limited and Cosmo Asset Management Co., Ltd.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Series B, Series A
  • Geography: Japan, United States, United Kingdom

Investor stats

  • Total investments: 76
  • Round size: Series A $17M–$241M; Series B $25M–$425M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: May invest from a new fund soon — raised $2.1B in 2018

Portfolio highlights

  • Blue Laser Fusion — Blue Laser Fusion is a commercial fusion company. Blue Laser Fusion is a laser startup to commercialize laser fusion by inventing its own laser and fusion reactor.
  • Alloyed — Alloyed delivers cutting-edge innovation in materials science, additive manufacturing, and advanced metallurgy. Explore our technologies and career opportunities.
  • Nanofiber Quantum Technologies — Discover how NanoQT builds the foundation for scalable quantum computing with nanofiber cavity-QED technology and high-fidelity quantum connectivity.
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Yokohama Capital
VC Fund · Yokohama, Kanagawa, Japan · 2 investments in Japan Biotechnology startups

Yokohama Capital as a venture capital firm conducts investment and rehabilitation support for small and medium-sized companies.

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Investment focus

  • Industry: Health Care, Information Technology, Artificial Intelligence
  • Stage:Series A, Series D
  • Geography: Japan

Investor stats

  • Total investments: 49
  • Round size: Series A $38k–$241M; Series D $7.4M–$780M
  • Lead/follow: 8% lead, 92% follow

Portfolio highlights

  • JPYC — JPYC is a financial institution that issues the community stablecoin JPYC, which is pegged to the yen of Japanese. They want to create a society where everyone can develop by fusing the real world with the world of cryptocurrencies and increasing the liquidity of capital to achieve their goal of overcoming the social conundrum. It will promotecapital's liquidity and create an environment that helps in development for all.
  • Varinos — Varinos is a clinical laboratory contract analysis company that is a partner of medical institutions. Varinos provides genomic testing development and contract analysis services using the latest technology, the next-generation sequencer.
  • Reborna Biosciences — Reborna Biosciences provides research and development in the field of genetic diseases. The company develops therapeutic options for area of unmet medical needs in genetic rare disease. The company's technology enables low-molecular compounds to target ribonucleic acid. The company provides new disease-modifying drugs for patients sufferingfrom rare genetic diseases including spinal muscular atrophy.
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Biotechnology Investor funding in Japan at a glance

Stats across 369 deals from 441 investors.

441
investors
in Japan Biotechnology startups
369
deals
in Japan Biotechnology startups
$35M
median round
in Japan Biotechnology startups
28%
lead investors
lead at least one round
20%
Series A
most common funding stage
98/2
VC / Angel
share of investor count

Access all 441 investors in Japan Biotechnology startups.

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