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Top 15 Medical VC Funds & Investors in South Africa (July 2026)

The most active venture capital funds investing in South Africa Medical startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Medical startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
54 Collective
VC Fund
2 Kenya, Nigeria, South Africa Seed, Pre-Seed Health Care, Information Technology, FinTech $40k–$4M
Psyence Biomedical
VC Fund
2 South Africa Corporate Round Medical, Health Care, Pharmaceutical $500k–$3.5M
Enza Capital
VC Fund
1 Kenya, Nigeria, South Africa Seed, Series A, Pre-Seed Financial Services, Finance, E-Commerce $100k–$31M
AngelHub Ventures
VC Fund
1 South Africa, Mexico, Colombia Seed, Series A, Pre-Seed Software, Information Technology, Education $300k–$2.3M
JPMorgan Chase & Co.
VC Fund
1 United States, Canada, Brazil Debt Financing, Post-IPO Debt, Grant Financial Services, FinTech, Software $400k–$18B
Goodwater Capital
VC Fund
1 United States, India, South Korea Seed, Series A, Series B FinTech, Financial Services, E-Commerce
ASISA Enterprise Development Fund
VC Fund
1 South Africa Medical, E-Commerce, Health Care
WZ Capital
VC Fund
1 South Africa Pre-Seed Medical, Wellness, Health Care
Ardent Capital
VC Fund
1 Nigeria, Indonesia, Thailand Seed, Pre-Seed, Series A E-Commerce, Internet, Software
Growth Grid Venture Capital Partners
VC Fund
1 South Africa Medical, Software, E-Commerce
PUSH Ventures
VC Fund
1 Austria, United States, Germany Seed, Series A Software, Apps, Health Care
AAIC Holdings
VC Fund
1 Togo, Nigeria, South Africa Seed, Series A Health Care, Medical, Apps
i-Cubed Capital
VC Fund
1 South Africa Seed, Pre-Seed, Private Equity Medical, Health Care, Personal Health $200k–$575k
Jozi Angels
VC Fund
1 South Africa, Kenya Pre-Seed, Seed B2B, Finance, Lending $39k–$1M
Foreign & Commonwealth Office - UK
VC Fund
1 Kenya, Mauritius, South Africa Seed, Pre-Seed Medical, Logistics, E-Commerce $500k–$790k
Access all 41 VC funds in South Africa Medical startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

54 Collective
VC Fund · Johannesburg, NA - South Africa, South Africa · 2 investments in South Africa Medical startups

Building and scaling African tech startups with catalytic capital, value-add support and our global network.

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Investment focus

  • Industry: Health Care, Information Technology, FinTech
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 108
  • Round size: Seed $40k–$4M; Pre-Seed $40k–$1.3M
  • Lead/follow: 35% lead, 65% follow

Portfolio highlights

  • Yeah — Yeah is a financial technology company that offers payment processing services while building a credit profile for the banked and unbanked.
  • REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
  • Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.
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Psyence Biomedical
VC Fund · Toronto, Ontario, Canada · 2 investments in South Africa Medical startups

Psyence Biomedical is a life science biotechnology company that focuses on advancement of psychedelic medicines.

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Investment focus

  • Industry: Medical, Health Care, Pharmaceutical
  • Stage:Corporate Round
  • Geography: South Africa

Investor stats

  • Total investments: 2
  • Round size: Corporate Round $500k–$3.5M
  • Lead/follow: 100% lead, 0% follow

Portfolio highlights

  • PsyLabs — PsyLabs focuses on cultivating and producing trippy active pharmaceutical ingredients and isolates for use in research, clinical trials, and medication development.
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Enza Capital
VC Fund · Nairobi, Nairobi Area, Kenya · 1 investments in South Africa Medical startups

Venture investor in high-growth Founders and Teams using technology to solve large and meaningful problems across Africa

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Investment focus

  • Industry: Financial Services, Finance, E-Commerce
  • Stage:Seed, Series A, Pre-Seed
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 53
  • Round size: Seed $617k–$8M; Pre-Seed $100k–$4M; Series A $3.6M–$31M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Djamo — Djamo is a Provider of financial applications to allow customers to use their cards with zero fees in a wide range of services.
  • Tugende — Tugende helps motorcycle taxi drivers own their own motorcycles in eighteen months or less instead of renting indefinitely. Ownership significantly increases income, job security and road safety.
  • Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.
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AngelHub Ventures
VC Fund · Stellenbosch, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Operating out of Stellenbosch in South Africa and backed by two family offices Angelhub Ventures's team is passionate about early stage investments in (South) Africa. Being entrepreneurial ourselves, we thoroughly understand the challenges and changes our founders face – which is why we back them in any way we can. Most importantly, we believein building great businesses and we are in it for the long haul.

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Investment focus

  • Industry: Software, Information Technology, Education
  • Stage:Seed, Series A, Pre-Seed
  • Geography: South Africa, Mexico, Colombia

Investor stats

  • Total investments: 14
  • Round size: Seed $2M–$2.3M; Series A $300k–$1.7M
  • Lead/follow: 71% lead, 29% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Motai
  • Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
  • Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.
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JPMorgan Chase & Co.
VC Fund · New York, New York, United States · 1 investments in South Africa Medical startups, 24 in the past 12 months

JPMorgan Chase & Co. provides innovative financial solutions for consumers, small businesses, corporations, governments, and institutions. The firm is serving customers, helping small businesses, or putting its skills to work with partners, they strive to identify issues and propose solutions that will propel the future and strengthen both itsclients and communities.

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Investment focus

  • Industry: Financial Services, FinTech, Software
  • Stage:Debt Financing, Post-IPO Debt, Grant
  • Geography: United States, Canada, Brazil

Investor stats

  • Total investments: 60
  • Round size: Grant $400k–$610k; Post-IPO Debt $20M–$18B; Debt Financing $15M–$867M
  • Lead/follow: 52% lead, 48% follow

Portfolio highlights

  • IKS Health — IKS Health delivers revenue cycle management, clinical support, and value based care solutions to create transformative value in healthcare.
  • GoodLife Fitness — From personal training to our fitness classes, the goal of every GoodLife Fitness club and gym is to help all Canadians live a fit and healthy good life.
  • Prometheus — Project Prometheus develops AI tools designed to learn from and interact with the physical world, rather than just process digital data. Its product efforts target engineering and manufacturing in aerospace, automotive, and computing sectors, using AI to optimize design, production, and performance.
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Goodwater Capital
VC Fund · Burlingame, California, United States · 1 investments in South Africa Medical startups, 67 in the past 12 months

Goodwater empowers exceptional entrepreneurs everywhere to change the world for the better. They believe consumer technology is a force on earth, shaping culture and transforming the global economy at unprecedented speed and scale. They invest in promising entrepreneurs to solve pressing problems. As a combined force, Goodwater companies are aglobal force for change, poised to measurably improve billions of lives.

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Investment focus

  • Industry: FinTech, Financial Services, E-Commerce
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, South Korea

Investor stats

  • Total investments: 316
  • Lead/follow: no public data

Portfolio highlights

  • Vendah — Social commerce platform democratizing the e-commerce in LATAM through local entrepreneurs
  • Zepto — India's fastest grocery delivery service.
  • TANGGapp — Send money to the Philippines with the best exchange rates! Money transfers are received in minutes. Get full transparency on your transaction - no FX markups or secret costs. Download TANGapp today and get started!
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ASISA Enterprise Development Fund
VC Fund · 1 investments in South Africa Medical startups

ASISA Enterprise Development Fund

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Investment focus

  • Industry: Medical, E-Commerce, Health Care
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
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WZ Capital
VC Fund · 1 investments in South Africa Medical startups

WZ Capital is a boutique venture capital firm investing in early-stage tech startups.

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Investment focus

  • Industry: Medical, Wellness, Health Care
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
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Ardent Capital
VC Fund · Bangkok, Krung Thep, Thailand · 1 investments in South Africa Medical startups, 7 in the past 12 months

Leading Venture Capital & Builder in Southeast Asia | Experts in E-Commerce, B2B, B2C, Fulfilment Startups | Seed, Series A Funding

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Investment focus

  • Industry: E-Commerce, Internet, Software
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Nigeria, Indonesia, Thailand

Investor stats

  • Total investments: 37
  • Lead/follow: no public data

Portfolio highlights

  • Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
  • Trade Lenda — With Trade Lenda, get quick finance in Nigeria without collateral.
  • Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.
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Growth Grid Venture Capital Partners
VC Fund · 1 investments in South Africa Medical startups

Growth Grid Venture Capital Partners

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Investment focus

  • Industry: Medical, Software, E-Commerce
  • Geography: South Africa

Investor stats

  • Total investments: 3
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.
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822 industries, 177 countries. Updated daily. Emails and phones included.

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PUSH Ventures
VC Fund · Vienna, Wien, Austria · 1 investments in South Africa Medical startups

We are an early-stage Venture Capital Firm investing in outstanding teams with convincing products and high growth potential.

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Investment focus

  • Industry: Software, Apps, Health Care
  • Stage:Seed, Series A
  • Geography: Austria, United States, Germany

Investor stats

  • Total investments: 23
  • Lead/follow: no public data

Portfolio highlights

  • FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
  • Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
  • Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.
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AAIC Holdings
VC Fund · Singapore, Central Region, Singapore · 1 investments in South Africa Medical startups

AAIC Holdingsis engages in nurturing investments in emerging countries, consulting and M&A, management outsourcing and human capital.

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Investment focus

  • Industry: Health Care, Medical, Apps
  • Stage:Seed, Series A
  • Geography: Togo, Nigeria, South Africa

Investor stats

  • Total investments: 7
  • Lead/follow: no public data

Portfolio highlights

  • Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
  • CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
  • RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.
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i-Cubed Capital
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

i-Cubed Capital provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retiremen, including savings plans with tax incentives.i-Cubed provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retirement, including savings plans with tax incentives. We assess fund managerperformances by reviewing fact sheets and provide our clients with a variety of options to meet their investment objectives.

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Investment focus

  • Industry: Medical, Health Care, Personal Health
  • Stage:Seed, Pre-Seed, Private Equity
  • Geography: South Africa

Investor stats

  • Total investments: 4
  • Round size: Pre-Seed $200k–$575k
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
  • Cape Doctors — CA Cape Doctors is a trusted private medical practice in Cape Town dedicated to providing high-quality primary healthcare services for individuals and families. With modern facilities located in Rondebosch and Claremont, the practice offers convenient access to professional medical care in a welcoming and patient-focused environment. Theexperienced team of doctors and healthcare professionals are committed to delivering safe, reliable, and comprehensive treatment for a wide range of medical needs.The practice provides a full spectrum of general practitioner services, including routine medical consultations, health screenings, chronic disease management, and treatment for acute illnesses. Patients can also access services such as blood tests, pathology, X-rays, minor procedures, and medical examinations for travel or visa requirements. CA Cape Doctors focuses on preventative healthcare, early diagnosis, and personalised treatment plans to help patients maintain long-term health and wellbeing.With flexible appointment scheduling, online booking options, and availability on weekends and public holidays, CA Cape Doctors aims to make quality healthcare accessible and convenient. The practice combines modern medical technology with compassionate care, ensuring that every patient receives professional attention and support tailored to their individual health needs.
  • NewForm Foods
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Jozi Angels
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Jozi Angels is an angel network based in Johannesburg, South Africa. We exist to grow the startup ecosystem and facilitate the growth of innovative startups.

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Investment focus

  • Industry: B2B, Finance, Lending
  • Stage:Pre-Seed, Seed
  • Geography: South Africa, Kenya

Investor stats

  • Total investments: 6
  • Round size: Pre-Seed $39k–$1M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Jahazii — Jahazii provides an online platform for workforce management. The company offers tools for storing and organizing employee records in one system. It manages scheduling, attendance tracking, and timesheets for different types of workers. The platform connects attendance and payroll functions to support salary processing. It allows employers toautomate payroll calculations and salary disbursement. The company also provides earned wage access, letting employees receive part of their pay before payday.
  • TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
  • The Awareness Company — We use data to tell stories that are useful to humans.
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Foreign & Commonwealth Office - UK
VC Fund · London, England, United Kingdom · 1 investments in South Africa Medical startups

Foreign & Commonwealth Office is a government organization that provides tourists and travellers with travel alerts, tips, and advice. It promotes the United Kingdom's interests overseas supporting its citizens and businesses around the globe.Foreign & Commonwealth Office has a worldwide network of embassies and consulates thatemploys over 14,000 people in nearly 270 diplomatic offices. It works with international organizations to promote British interests and global security, including the EU, NATO, Foreign & Commonwealth Office was founded on January 1, 1936 and is based in London, United Kingdom.

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Investment focus

  • Industry: Medical, Logistics, E-Commerce
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Mauritius, South Africa

Investor stats

  • Total investments: 4
  • Round size: Seed $500k–$790k
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
  • HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
  • Raino Tech4Impact — Raino Tech4Impact is a social enterprise that leverages technology as an enabler to empower African communities. We have been deploying technology-driven solutions in agriculture and health, powered by renewable energy to achieve sustainability.
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Medical VC funding in South Africa at a glance

Stats across 33 deals from 41 investors.

41
investors
in South Africa Medical startups
33
deals
in South Africa Medical startups
$328k
median round
in South Africa Medical startups
44%
lead investors
lead at least one round
15%
Private Equity
most common funding stage

Access all 41 VC funds in South Africa Medical startups.

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