Top 25 Medical VC Funds & Investors in South Africa (August 2026)

Portfolio highlights

• Zazu — Zazu is a neobank for African SMEs, offering seamless banking tools, cash flow automation, and real-time insights. Zazu simplifies finance management in one all-in-one solution.
• Fincart — Fincart is a leading shipping platform in Egypt, connecting your business with top courier services, automating operations, and helping you scale your eCommerce logistics.
• Udu Technologies — Udu Technologies is an AI infrastructure company that offers GPU systems, AI platform integration, and technical support services.

Portfolio highlights

• Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
• MariHealth Solutions (RF) (PTY) LTD — Proteomics-powered analytics for aquaculture. We quantify 3,000+ proteins per sample to deliver deep biological insights for fish health, nutrition, and farming.

Portfolio highlights

• Kaon — Chat with AI characters for free on FlowGPT! More than 1 million characters and bots to chat with, AI boyfriend, girlfriend, uncencored chat and AI tools.
• RedotPay — Where Crypto Meets Real Life | Trusted by 8M+ | Accepted at 130M+ merchants | Pay with BTC, ETH, USDC, USDT & more
• Pure — Pure Poker is a privately held fintech and software company that develops a legal, compliant, rake-free real-money online poker platform. Headquartered in San Francisco, California, the company replaces the traditional casino "house" model with a trusted, identity-verified social gaming network.

Portfolio highlights

• Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
• Trade Lenda — Trade Lenda: Access to Loans, Investments, Utility Payments, Credit Access, Insurance, and More! Unlock Opportunities to Earn, Invest, and Grow. Secure Personal or Business Loans Toda
• Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.

Portfolio highlights

• LipaLater — LipaLater is a lending marketplace that provides postpaid payments at e-commerce stores. They are making technology affordable for you. Get the electronic of your choice today and pay for it in comfortable monthly installments.
• REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
• Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.

Portfolio highlights

• Cuoral — Proactive customer success and engagement. We help you reduce customer churn and increase retention and revenue.
• BankWise — Liga123 merupakan situs slot jackpot 888 slots paling gacor dan juga platform ini terdata paling banyak dicari hari ini karena memiliki akses yang mudah tanpa harus menggunakan Apk tambahan seperti VPN untuk memainkan game favorit.
• PowerLabs — PowerLabs is an energy and climate technology research and implementation company whose goal is to use intelligent energy to build a world where human output is boundless.

Portfolio highlights

• PsyLabs — Licensed Cultivation and Production Facility - International Supplier of Pharmaceutical Grade Psychoactive Compounds

Portfolio highlights

• Contro — Explore a range of health services, wellness solutions, and expert treatments at Zapmed. Personalized care plans to help you live a healthier life.
• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• SigmaX — Math app to help learners&any other ordinary person to better understand math & learn it a fun way. Available on Google play store & via https://t.co/hMzLOv2qXZ

Portfolio highlights

• Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.

Portfolio highlights

• Yakeey — Yakeey is an end-to-end transactional marketplace that radically simplifies the experience of buying, selling and renting real estate.We leverage on data and technology to connect all real estate market players through a state of the art platform, create a chain of trust and powerful network effects and accelerate transactions.Yakeey is builton a community of real estate advisors, YakeeyPRO, to deliver a continuous professional and tailored service at every step of the transaction.
• Orca Fraud — Orca empowers fraud fighters with effective tools to combat fraud
• Aethex — End to end voice agents localized for your market.

Portfolio highlights

• Motai —
• Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
• Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.

Portfolio highlights

• ESI Energy Services — ESI Energy Services provides pipeline equipment rental and sales services.
• Battery Mineral Resources — Battery Mineral Resources is a multi-commodity battery materials provider focused on the development .
• Copenhagen Infrastructure Partners — Copenhagen Infrastructure Partners is a multinational team with extensive experience and knowledge within the fields of regulated infrastructure and renewable energy. The team has a broad range of competencies within corporate finance, merger & acquisitions, engineering, project development and project management.BACKGROUND OF THE PARTNERSThe CIP partners have extensive experience within the infrastructure and energy space and have significant knowledge of mergers & acquisitions, project development, corporate finance, financial structuring, construction management, and operational management.All partners have a corporate background and have held top management positions at inter alia DONG Energy. The partners have managed, been directly involved in and responsible for the construction and operation of some of Europe’s largest energy projects.

Portfolio highlights

• Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
• HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
• Keep IT Cool — Raino Tech4Impact is a social enterprise that leveraging technology as an enabler to empower African communities. Founded in 2014, They have been developing technology-driven solutions in health, agriculture, sports, green energy and offer business support services.In partnership with various key players in different sectors, they have developedunique and efficient different use cases of technological solutions impacting millions of lives.

Portfolio highlights

• BIMA — BIMA is an insurtech player using mobile technology to provide insurance and health services to emerging markets. To serve its customers, the company has developed a proprietary technology platform, established exclusive partnerships with mobile operators, and built relationships with international insurers. BIMA utilizes its technology platform toserve customers in 13 countries across Asia, Africa, and Latin America and has reached to date 31 million subscribers.
• CrowdForce — CrowdForce is an offline distribution network for market research and financial services. The company empowers businesses to drive mass adoption of digital, crypto, and financial services through the use of mobile technology to help businesses, banks, digital wallets, multinational organizations, NGOs, and government agencies to reach theunderserved population in their communities.CrowdForce was founded in 2016 and is headquartered in San Francisco, California.
• Helium Health — Helium Health empowers healthcare providers in Africa with digital tools, financing solutions, and data partnerships. Learn more about our innovative solutions.

Portfolio highlights

• MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
• AURA — A South African cloud-based security and safety startup .
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• Jahazii — Jahazii helps employers offer on-demand access to earned wages, giving employees financial flexibility without loans while reducing pressure on HR and payroll teams. Funds on M-PESA in seconds, at no cost to you.
• TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
• The Awareness Company — We use data to tell stories that are useful to humans.

Portfolio highlights

• CubeSpace — Industry-leading modular attitude determination and control (ADCS) products and solutions. Laser-focused on our customers' success. Your global ADCS partner.
• SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
• Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.

Portfolio highlights

• RICE — RCIE is a co-working ecosystem that connects entrepreneurs to a customized curriculum, corporate partners, and access to capital. It is designed to connect the next generation of multi-cultural and women entrepreneurs to the tools and relationships required to turn dreams into reality.The company was founded in 2016 and is headquartered inAtlanta, Georgia.
• PopID — PopID offers a facial recognition platform that enables users to authenticate identity and process payments through biometric verification. Its core service, PopPay, allows customers to link their facial image to a payment method, facilitating transactions at participating businesses without the need for physical cards or mobile devices. The systemsupports various retail formats, including kiosks, drive-thrus, and counter services, and integrates with loyalty programs to personalize the customer experience. PopID's technology has been adopted by merchants such as Whataburger and Steak 'n Shake, aiming to streamline ordering and checkout processes. The company emphasizes user consent and data security, storing encrypted biometric data and allowing users to opt-in or out at their discretion. PopID has also expanded internationally, partnering with entities like SoftBank's Japan Computer Vision to introduce its services in markets such as Japan.
• Shopware — Shopware is a trendsetting ecommerce platform to power your online business. Our ecommerce solution offers the perfect combination of beauty & brains you need to build and customize a fully responsive online store.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.

Portfolio highlights

• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
• Cape Doctors — CA Cape Doctors is a trusted private medical practice in Cape Town dedicated to providing high-quality primary healthcare services for individuals and families. With modern facilities located in Rondebosch and Claremont, the practice offers convenient access to professional medical care in a welcoming and patient-focused environment. Theexperienced team of doctors and healthcare professionals are committed to delivering safe, reliable, and comprehensive treatment for a wide range of medical needs.The practice provides a full spectrum of general practitioner services, including routine medical consultations, health screenings, chronic disease management, and treatment for acute illnesses. Patients can also access services such as blood tests, pathology, X-rays, minor procedures, and medical examinations for travel or visa requirements. CA Cape Doctors focuses on preventative healthcare, early diagnosis, and personalised treatment plans to help patients maintain long-term health and wellbeing.With flexible appointment scheduling, online booking options, and availability on weekends and public holidays, CA Cape Doctors aims to make quality healthcare accessible and convenient. The practice combines modern medical technology with compassionate care, ensuring that every patient receives professional attention and support tailored to their individual health needs.
• NewForm Foods — We are leveraging a continent-spanning R&D network to help food producers develop and scale cultivated animal products, fast & affordably.

Portfolio highlights

• Strove — Healthier people. Stronger businesses. Your employees are your greatest asset. Taking care of their physical and mental health has never been more important.
• EnviSync — EnviSync is a Large Language Model Operations (LLMops) platform specifically designed to empower global enterprises, particularly in regulated sectors such as finance, healthcare, and legal tech. The platform facilitates the deployment, monitoring, and optimization of LLM applications with high precision. Developed by experts from technology andinstitutional finance, EnviSync addresses critical challenges, including regulatory compliance with standards like GDPR and MiFID II, performance drift detection, and managing inference costs that can impact operational efficiency.
• InfiniNest — InfiniNest is an innovative Adaptive Learning Companion designed to revolutionize education for special children. Leveraging advanced Large Language Models and deep learning, InfiniNest tailors learning materials to each child's unique needs, from dyslexia to autism spectrum disorder. It offers interactive, multimodal content and real-timefeedback, making learning accessible and engaging. InfiniNest also integrates assistive technologies and provides continuous assessment, helping educators and parents track progress and identify areas for support. By fostering collaborative learning and emotional well-being, InfiniNest ensures every child has the tools to succeed and thrive in their educational journey.

Portfolio highlights

• Plentify — Plentify connects home appliances with cheaper cleaner energy. It does this with an intelligent residential load management platform which matches demand with clean energy supply for 75% cheaper than batteries. Plentify combines advanced hardware, AI, and user-centric design to create smart home products that delight customers while alsostrengthening electricity systems.
• Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
• Contactable — Digital Identity Orchestration platform - used extensively by corporates across all sectors for digital onboarding, e-KYC, Self-RICA and identity proofing.

Portfolio highlights

• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.

Portfolio highlights

• Gustav — Modern staffing teams use Gustav's VMS to source talent from trusted sub-vendors. Fast, secure, and compliant!
• Voltrac — Building electric autonomous vehicles for farming & frontline logistics
• enspired — Revolutionize battery storage with AI-powered BESS optimization. Our energy trading platform ensures smart, real-time market access. Contact us today!

Portfolio highlights

• Lupiya — Lupiya is a financial technology company that provides digital lending services designed to help individuals and small businesses access short-term credit and installment financing. The platform offers mobile-accessible loans that can be used for expenses such as personal needs, business cash flow, or emergency payments, using an online applicationprocess that evaluates creditworthiness through alternative data and behavioral indicators. Lupiya’s services include flexible repayment schedules, automated disbursement, and electronic account management so users can monitor balances and repayment activity within the app or web interface. The company also offers tools for budgeting and payment reminders to support borrowers in managing their credit obligations. Through integrations with local payment networks and banking partners, Lupiya facilitates secure fund transfers and compliance with financial regulations. Its lending infrastructure is tailored to expand access to credit for underserved populations and small enterprises that may have limited access to traditional banking services.
• Seamfix — Seamfix’s end-to-end electronic ID and credentials software solutions address the lack of digital ID systems for 30+ African countries and over 250M individuals, providing access to credit, banking, and other essential services for large parts of populations.
• Alma Clinics — ALMA CLINICS Primary Healthcare with Advanced Blockchain, AI technology. BEST Clinic providing affordable healthcare, Soweto, Johannesburg, South Africa.