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Top 15 Medical VC Funds & Investors in South Africa (June 2026)

The most active venture capital funds investing in South Africa Medical startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Medical startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
54 Collective
VC Fund
2 Kenya, Nigeria, South Africa Seed, Pre-Seed Health Care, Information Technology, FinTech $40k–$4M
ASISA Enterprise Development Fund
VC Fund
1 South Africa Medical, E-Commerce, Health Care
WZ Capital
VC Fund
1 South Africa Pre-Seed Medical, Wellness, Health Care
Ardent Capital
VC Fund
1 Nigeria, Indonesia, Thailand Seed, Pre-Seed, Series A E-Commerce, Internet, Software
Growth Grid Venture Capital Partners
VC Fund
1 South Africa Medical, Software, E-Commerce
PUSH Ventures
VC Fund
1 Austria, United States, Germany Seed, Series A Software, Apps, Health Care
AAIC Holdings
VC Fund
1 Togo, Nigeria, South Africa Seed, Series A Health Care, Medical, Apps
HAVAÍC
VC Fund
1 South Africa, United States, Kenya Seed, Series A Software, Health Care, FinTech $57k–$15M
Enza Capital
VC Fund
1 Kenya, Nigeria, South Africa Seed, Series A Financial Services, Finance, E-Commerce $238k–$31M
PayPal
VC Fund
1 United States, Ireland, Sweden Seed, Grant Financial Services, FinTech, Marketplace $15k–$18M
i-Cubed Capital
VC Fund
1 South Africa Pre-Seed Medical, Wellness, Health Care
Jozi Angels
VC Fund
1 South Africa Pre-Seed, Seed B2B, Medical, Software $39k–$1M
AngelHub Ventures
VC Fund
1 South Africa, Mexico, Colombia Seed, Series A Software, Information Technology, Education $300k–$2.3M
JPMorgan Chase & Co.
VC Fund
1 United States, Brazil, Canada Debt Financing, Seed FinTech, Software, Financial Services $4.2M–$800M
Goodwater Capital
VC Fund
1 United States, India, South Korea Seed, Series A, Series B FinTech, Financial Services, E-Commerce
Access all 33 VC funds in South Africa Medical startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

54 Collective
VC Fund · Johannesburg, NA - South Africa, South Africa · 2 investments in South Africa Medical startups

Building and scaling African tech startups with catalytic capital, value-add support and our global network.

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Investment focus

  • Industry: Health Care, Information Technology, FinTech
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 107
  • Round size: Seed $40k–$4M; Pre-Seed $40k–$1.3M
  • Lead/follow: 36% lead, 64% follow

Portfolio highlights

  • mTek — mTek is a digital online insurance platform that provides an entirely paperless ecosystem for the insurance industry.
  • REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
  • Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.
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ASISA Enterprise Development Fund
VC Fund · 1 investments in South Africa Medical startups

ASISA Enterprise Development Fund

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Investment focus

  • Industry: Medical, E-Commerce, Health Care
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
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WZ Capital
VC Fund · 1 investments in South Africa Medical startups

WZ Capital is a boutique venture capital firm investing in early-stage tech startups.

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Investment focus

  • Industry: Medical, Wellness, Health Care
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
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Ardent Capital
VC Fund · Bangkok, Krung Thep, Thailand · 1 investments in South Africa Medical startups, 7 in the past 12 months

Leading Venture Capital & Builder in Southeast Asia | Experts in E-Commerce, B2B, B2C, Fulfilment Startups | Seed, Series A Funding

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Investment focus

  • Industry: E-Commerce, Internet, Software
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Nigeria, Indonesia, Thailand

Investor stats

  • Total investments: 37
  • Lead/follow: no public data

Portfolio highlights

  • Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
  • Trade Lenda — With Trade Lenda, get quick finance in Nigeria without collateral.
  • Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.
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Growth Grid Venture Capital Partners
VC Fund · 1 investments in South Africa Medical startups

Growth Grid Venture Capital Partners

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Investment focus

  • Industry: Medical, Software, E-Commerce
  • Geography: South Africa

Investor stats

  • Total investments: 3
  • Lead/follow: no public data

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.
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PUSH Ventures
VC Fund · Vienna, Wien, Austria · 1 investments in South Africa Medical startups

We are an early-stage Venture Capital Firm investing in outstanding teams with convincing products and high growth potential.

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Investment focus

  • Industry: Software, Apps, Health Care
  • Stage:Seed, Series A
  • Geography: Austria, United States, Germany

Investor stats

  • Total investments: 23
  • Lead/follow: no public data

Portfolio highlights

  • FERNRIDE — Fernride enables automated, sustainable logistics by combining the skills of remote drivers with autonomous technologies.
  • Valutico — Valutico is the world‘s leading provider of web-based company valuation tools.Started in 2014 by a team of enthusiastic Corporate Finance professionals and web developers, the concept was born out of frustration with the status-quo in Corporate Finance practice: That professional company valuations used to be the domain of only the mostsophisticated of investors.At Valutico, it has been their mission from the outset to offer cutting-edge valuation tools to a much wider audience. Today they empower everybody to perform company valuations that meet and exceed the standards of even the leading investment banks and advisory firms.The company today is headquartered in Vienna/Austria and has an additional office in Frankfurt/Germany.
  • Ohana — Ohana helps you to protect your child in the digital world. Limit screentime, get insights & guidance, block apps & websites and filter inappropriate content.
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AAIC Holdings
VC Fund · Singapore, Central Region, Singapore · 1 investments in South Africa Medical startups

AAIC Holdingsis engages in nurturing investments in emerging countries, consulting and M&A, management outsourcing and human capital.

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Investment focus

  • Industry: Health Care, Medical, Apps
  • Stage:Seed, Series A
  • Geography: Togo, Nigeria, South Africa

Investor stats

  • Total investments: 7
  • Lead/follow: no public data

Portfolio highlights

  • Gozem — Gozem is a transport technology platform for Francophone West and Central Africa.
  • CrowdForce — We empower businesses to drive mass adoption of digital, and financial services to underserved population in their communities.
  • RelianceHMO — RelianceHMO is solving this problem by providing affordable and reliable insurance packages for the average African. Reliance makes health insurance in Africa cheaper and easier to access by combining Telemedicine with data science.
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HAVAÍC
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

HAVAÍC is an investment and advisory firm that specialises in early-stage, high-growth African businesses with proven concepts and global prospects, offering investment opportunities to sophisticated investors and international venture capital companies with an interest in Africa. As a complementary offering, HAVAÍC provides corporate advisory andcapital raising services to emerging, internationally scalable businesses.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Seed, Series A
  • Geography: South Africa, United States, Kenya

Investor stats

  • Total investments: 43
  • Round size: Seed $57k–$4M; Series A $1.9M–$15M
  • Lead/follow: 60% lead, 40% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • AURA — A South African cloud-based security and safety startup .
Show all investments...

Enza Capital
VC Fund · Nairobi, Nairobi Area, Kenya · 1 investments in South Africa Medical startups

Venture investor in high-growth Founders and Teams using technology to solve large and meaningful problems across Africa

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Investment focus

  • Industry: Financial Services, Finance, E-Commerce
  • Stage:Seed, Series A
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 48
  • Round size: Seed $238k–$12M; Series A $3.6M–$31M
  • Lead/follow: 21% lead, 79% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Craydel — Craydel is transforming the way students and working professionals in Africa discover, compare and apply to higher education. Our online platform has thousands of quality undergraduate, postgraduate and vocational programs offering degrees, diplomas and degrees, certificates from leading universities and colleges in 15 countries around the world.Many of these programs are even available online from the comfort of your home.Craydel makes it easy for you to compare and select the programs and institutions that best fit your career goals, personality, grades and budget.
  • Tugende — Tugende helps motorcycle taxi drivers own their own motorcycles in eighteen months or less instead of renting indefinitely. Ownership significantly increases income, job security and road safety.
  • Quro Medical — Quro Medical is an innovative digital health company pioneering premium hospital-at-home services.
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PayPal
VC Fund · San Jose, California, United States · 1 investments in South Africa Medical startups

PayPal has remained at the forefront of the digital payment revolution for more than 20 years. By leveraging technology to make financial services and commerce more convenient, affordable, and secure, the PayPal platform is empowering more than 375 million consumers and merchants in more than 200 markets to join and thrive in the global economy.

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Investment focus

  • Industry: Financial Services, FinTech, Marketplace
  • Stage:Seed, Grant
  • Geography: United States, Ireland, Sweden

Investor stats

  • Total investments: 33
  • Round size: Seed $45k–$18M; Grant $15k–$110k
  • Lead/follow: 33% lead, 67% follow

Portfolio highlights

  • Fordefi — The MPC wallet platform and Web3 gateway from Fordefi allow institutions to connect to dApps across multiple chains while keeping digital assets secure. Fordefi is the first institutional MPC wallet and security platform designed for decentralised finance. It provides MPC key management, self-service DeFi policy controls, time-of-transaction smartcontract insights, transaction simulation, and risk alerts.
  • Padiepal — Discover the Future of Digital Finance with Padiepal Transforming Digital Finance At Padiepal, we're on a mission to redefine the future of digital finance. With an ever-growing range of innovative services, we cater to the needs of individuals, businesses, and global merchants alike. Our objective is to provide seamless transactions andfinancial solutions that meet the demands of today's fast-paced digital world.Comprehensive Services for Everyone Our offerings are designed to empower users to manage their finances effectively. From dollar virtual accounts to international money transfers, we have services that enhance the user experience. Individuals can enjoy straightforward payment solutions, while businesses can utilize our robust tools to expand their operations globally. By combining technology with financial expertise, Padiepal facilitates smart financial decisions for everyone.Why Choose Padiepal? With a commitment to security and transparency, Padiepal is a trustworthy partner in your financial journey. Our user-friendly interface simplifies engaging with digital finance, making it accessible to all. Moreover, we continuously innovate and adapt our services to remain at the forefront of digital finance trends. Whether you’re a seasoned merchant or just starting your financial journey, Padiepal stands ready to support your goals.
  • CoPilot — CoPilot is pioneering Assisted Commerce for big-ticket purchases – starting with cars. You are the one spending the money - shouldn't you have an expert on your side? We founded CoPilot to make that a reality. For the average car buyer, who is not a car expert or enthusiast, car shopping can be a time consuming, frustrating process that leavespeople feeling alone and disadvantaged. CoPilot is changing this dynamic. Like a trusted friend who is knowledgeable about cars, knows where to look and what to buy, CoPilot provides car shoppers with an expert partner who empowers them to discover the perfect car at the best possible price with ease and confidence.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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i-Cubed Capital
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

i-Cubed Capital provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retiremen, including savings plans with tax incentives.i-Cubed provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retirement, including savings plans with tax incentives. We assess fund managerperformances by reviewing fact sheets and provide our clients with a variety of options to meet their investment objectives.

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Investment focus

  • Industry: Medical, Wellness, Health Care
  • Stage:Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 2
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
  • Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
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Jozi Angels
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Jozi Angels is an angel network based in Johannesburg, South Africa. We exist to grow the startup ecosystem and facilitate the growth of innovative startups.

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Investment focus

  • Industry: B2B, Medical, Software
  • Stage:Pre-Seed, Seed
  • Geography: South Africa

Investor stats

  • Total investments: 4
  • Round size: Pre-Seed $39k–$1M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — Weight Loss TreatmentHealth Coach Support
  • TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
  • The Awareness Company — We use data to tell stories that are useful to humans.
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AngelHub Ventures
VC Fund · Stellenbosch, NA - South Africa, South Africa · 1 investments in South Africa Medical startups

Operating out of Stellenbosch in South Africa and backed by two family offices Angelhub Ventures's team is passionate about early stage investments in (South) Africa. Being entrepreneurial ourselves, we thoroughly understand the challenges and changes our founders face – which is why we back them in any way we can. Most importantly, we believein building great businesses and we are in it for the long haul.

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Investment focus

  • Industry: Software, Information Technology, Education
  • Stage:Seed, Series A
  • Geography: South Africa, Mexico, Colombia

Investor stats

  • Total investments: 13
  • Round size: Seed $2M–$2.3M; Series A $300k–$1.7M
  • Lead/follow: 77% lead, 23% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
  • Godochurch — GoDoChurch is a cloud-based church administration software which is designed to assist Christian churches and ministries with managing members, Sunday services, events, communications, and more. The system is made up of a base package, covering messaging, news, ministries, lists, church roles, services, events, and growth paths, with additionalmodules for managing follow-ups, groups, and Kids church.
  • Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.
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JPMorgan Chase & Co.
VC Fund · New York, New York, United States · 1 investments in South Africa Medical startups

JPMorgan Chase & Co. provides innovative financial solutions for consumers, small businesses, corporations, governments, and institutions. The firm is serving customers, helping small businesses, or putting its skills to work with partners, they strive to identify issues and propose solutions that will propel the future and strengthen both itsclients and communities.

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Investment focus

  • Industry: FinTech, Software, Financial Services
  • Stage:Debt Financing, Seed
  • Geography: United States, Brazil, Canada

Investor stats

  • Total investments: 38
  • Round size: Seed $4.2M–$10M; Debt Financing $15M–$800M
  • Lead/follow: 47% lead, 53% follow

Portfolio highlights

  • AT&T — AT&T is a telecommunications company that provides wireless communications, local exchange, and long-distance services for consumers and businesses in the United States and internationally.The company offers its services in two segments: wireless and wireline. Its wireless segment offers various wireless voice, data, text, and otherservices. This segment sells various handsets, wirelessly-enabled computers, and wireless data cards for personal computers through its owned stores, agents, and third-party retail stores. It also sells accessories comprising carrying cases, hands-free devices, batteries, battery chargers, and other items to consumers as well as to agents and third-party distributors. As of December 31, 2013, this segment served approximately 110 million wireless subscribers.The company’s wireline segment provides data services such as switched and dedicated transport, DSL internet access, network integration, managed web hosting, packet, and enterprise networking services as well as local, interstate, and international wholesale networking capacity solutions to other service providers. This segment also offers voice services consisting of local and long-distance services; wholesale switched access services to other service providers; and outsourcing and integration services as well as CPE and government-related services. This segment has served approximately 12 million retail consumers, 10 million retail businesses, and 2 million wholesale access lines.AT&T is headquartered in Dallas, Texas.
  • FairPlay24 — The world's first Fairness-as-a-Service company, offering tools that embed fairness into AI decision-making and reducing algorithmic bias.
  • GoodLife Fitness — From personal training to our fitness classes, the goal of every GoodLife Fitness club and gym is to help all Canadians live a fit and healthy good life.
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Goodwater Capital
VC Fund · Burlingame, California, United States · 1 investments in South Africa Medical startups, 67 in the past 12 months

Goodwater empowers exceptional entrepreneurs everywhere to change the world for the better. They believe consumer technology is a force on earth, shaping culture and transforming the global economy at unprecedented speed and scale. They invest in promising entrepreneurs to solve pressing problems. As a combined force, Goodwater companies are aglobal force for change, poised to measurably improve billions of lives.

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Investment focus

  • Industry: FinTech, Financial Services, E-Commerce
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, South Korea

Investor stats

  • Total investments: 316
  • Lead/follow: no public data

Portfolio highlights

  • Vendah — Social commerce platform democratizing the e-commerce in LATAM through local entrepreneurs
  • Zepto — India's fastest grocery delivery service.
  • TANGGapp — Send money to the Philippines with the best exchange rates! Money transfers are received in minutes. Get full transparency on your transaction - no FX markups or secret costs. Download TANGapp today and get started!
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Medical VC funding in South Africa at a glance

Stats across 24 deals from 33 investors.

33
investors
in South Africa Medical startups
24
deals
in South Africa Medical startups
$241k
median round
in South Africa Medical startups
36%
lead investors
lead at least one round
21%
Seed
most common funding stage

Access all 33 VC funds in South Africa Medical startups.

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