Top 5 Cryptocurrency VC (Venture Capital) Funds in South Africa in September 2025

Last updated: Sep 2025 A list of 5 VC (Venture Capital) funds that invest in Cryptocurrency startups based in South africa. We rank investors based on the number of investments they made in Cryptocurrency companies from South africa. We update this investor list every month.

Top 5 Cryptocurrency VC (Venture Capital) Funds in South Africa in September 2025

Investor	Cryptocurrency South Africa investments
Newtown Partners	2
Montegray Capital	1
10x Group	1
Bittrex Global	1
4Di Capital	1

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Investor list

Newtown Partners is a venture capital firm that actively invests in emerging, disruptive technology startups.

Investment focus

Logistics, Health Care, Information Technology
Seed, Series A, Funding Round
South Africa, Ghana, Kenya

Portfolio highlights

MDaaS Global — At MDaaS Global, we build and operate modern, tech-enabled diagnostic centres in clinically-underserved communities, starting in Nigeria. Our big goal is to create affordable healthcare solutions for Africa's next billion.
Chefaa — Chefaa is a GPS-enabled pharmacy benefits platform connecting patients & pharmacies nation-wide to help patients manage all their pharmacy needs. Chefaa uses big data, data ming & machine learning
Waspito — We are the platform that engages Africa into the conversation and action to drive affordable and accessible quality healthcare across the continent.

Investment focus

Bitcoin, FinTech, Ethereum
Seed
South Africa

Portfolio highlights

VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay

10x Group is a group of serial entrepreneurs and founders investing in founders of digital start-ups in Europe and Silicon Valley.

Investment focus

Software, SaaS, Information Technology
Seed, Series A, Funding Round
United States, Germany, India

Portfolio highlights

enmacc — enmacc, the OTC energy trading platform, offers innovative solutions for efficient trading of energy commodities in today's dynamic market.
finway — finway provides financial guidence to SMEs, plan & control all expenses and budgets in one tool.
Quantum Systems — Our vision is to become the global leader in providing aerial data for decision making by the use of our drones.

Bittrex operates as a digital asset trading platform. Bittrex is the premier U.S.-based digital asset trading platform, providing lightning-fast trade execution, dependable digital wallets and industry-leading security practices.

Investment focus

Bitcoin, FinTech, Ethereum
Series A
South Africa

Portfolio highlights

VALR — Buy and sell bitcoin, ethereum & more | Pay anyone for free with VALR Pay

4Di Capital is an independent seed- and early-stage technology venture capital firm based in Cape Town, South Africa.Nurture capital is the term that best describes 4Di Capitalâ€:tm:s purpose and philosophy.We understand that in the early days of any business, support, mentoring and access to networks is just as important as seed capital.Using tried and tested international venture capital best practices, adapted for local use, we believe in entrepreneur-friendly finance without frills, and in working as a team with our investments to achieve their true potential.4Di Capital Early-Stage Technology Fund 1 targets startup investment opportunities with high growth potential at the seed- and early-stages in the mobile, enterprise software and web sectors.We look for founder teams with hungry passion, commitment, domain expertise and deep insights into the large market problems they wish to solve with their technology solutions.