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Top 5 Life Science VC Funds & Investors in South Africa (August 2026)

The most active venture capital funds investing in South Africa Life Science startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Life Science startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Oak Drive ventures
VC Fund
1 Philippines, France, Singapore Seed, Series B, Series A Banking, FinTech, Financial Services $2M–$131M
Futuregrowth Asset Management
VC Fund
1 South Africa, France, United States Seed, Series A Software, Transportation, Financial Services $1.8M–$11M
Unruly Capital
VC Fund
1 United Kingdom, United States, Germany Seed, Pre-Seed, Venture - Series Unknown Biotechnology, Artificial Intelligence, CleanTech $908k–$55M
University Technology Fund
VC Fund
1 South Africa Seed, Grant Biotechnology, AgTech, Medical $467k–$5M
E4EAfrica
VC Fund
1 South Africa, The Netherlands, France Seed, Pre-Seed, Series A Logistics, Internet, Supply Chain Management $1M–$7.5M
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Investor list

Oak Drive ventures
VC Fund · Fort Bonifacio, Quezon City, Philippines · 1 investments in South Africa Life Science startups

Oak Drive ventures will provide management support to a growing stable of operating companies. It combines decades of operational and investment experience to create value across various industries.

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Investment focus

  • Industry: Banking, FinTech, Financial Services
  • Stage:Seed, Series B, Series A
  • Geography: Philippines, France, Singapore

Investor stats

  • Total investments: 9
  • Round size: Seed $5.3M–$6.5M; Series A $2M–$3M; Series B $50M–$131M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Hive Health — Hive Health is a digital platform that provides access to easy-to-use, affordable, and quality HMO plans for SMEs in the Philippines.
  • Netbank — Netbank provides various banking solutions like alternative lenders, payment solutions, neobanks, and wallets.
  • Kraver's Canteen — Kraver's Canteen is an online F&B brand builder, operating the fastest growing cloud kitchen network in the Philippines. Can't agree what to order for the family? Satisfy every craving with the best delivery brands in the Manila, with just one delivery fee!
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Futuregrowth Asset Management
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Life Science startups

Futuregrowth manages the full range of fixed interest and developmental impact funds on behalf of our clients. We are committed to managing and investing our clients' funds in a responsible manner.

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Investment focus

  • Industry: Software, Transportation, Financial Services
  • Stage:Seed, Series A
  • Geography: South Africa, France, United States

Investor stats

  • Total investments: 20
  • Round size: Seed $1.8M–$5.3M; Series A $3.4M–$11M
  • Lead/follow: 70% lead, 30% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • CubeSpace — Industry-leading modular attitude determination and control (ADCS) products and solutions. Laser-focused on our customers' success. Your global ADCS partner.
  • SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
  • Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
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Unruly Capital
VC Fund · Italy, Texas, United States · 1 investments in South Africa Life Science startups

Investing in the crazy before it becomes normal

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Investment focus

  • Industry: Biotechnology, Artificial Intelligence, CleanTech
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: United Kingdom, United States, Germany

Investor stats

  • Total investments: 62
  • Round size: Seed $1.2M–$9.3M; Pre-Seed $908k–$3.6M; Venture - Series Unknown $1.6M–$55M
  • Lead/follow: 6% lead, 94% follow

Portfolio highlights

  • Matta — Creating AGI to manufacture the impossible.
  • Willo — Willo is advancing and scaling true wireless power for humanity, technology, and industry. Discover the company powering the next era of energy delivery.
  • Tangible — Tangible empowers hardware companies with sustainable asset-based lending solutions. Our platform streamlines debt funding, compliance automation, and financial product design, enabling efficient capital mobilization and comprehensive reporting for a greener future. Scale your business with Twist.
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University Technology Fund
VC Fund · Stellenbosch, NA - South Africa, South Africa · 1 investments in South Africa Life Science startups

The University Technology Fund specifically focusses on commercialising technology, intellectual property, and research - Visit Us!

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Investment focus

  • Industry: Biotechnology, AgTech, Medical
  • Stage:Seed, Grant
  • Geography: South Africa

Investor stats

  • Total investments: 20
  • Round size: Seed $484k–$5M; Grant $467k–$473k
  • Lead/follow: 40% lead, 60% follow

Portfolio highlights

  • Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
  • Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
  • MariHealth Solutions (RF) (PTY) LTD — Proteomics-powered analytics for aquaculture. We quantify 3,000+ proteins per sample to deliver deep biological insights for fish health, nutrition, and farming.
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E4EAfrica
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Life Science startups

E4E Africa Backing category-defining emerging market businesses. We invest in businesses that drive economic opportunity and sustainable growth.Learn MoreE4E specializes ... Read More

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Investment focus

  • Industry: Logistics, Internet, Supply Chain Management
  • Stage:Seed, Pre-Seed, Series A
  • Geography: South Africa, The Netherlands, France

Investor stats

  • Total investments: 25
  • Round size: Seed $2.7M–$7.5M; Pre-Seed $1M–$2M; Series A $1M–$5.4M
  • Lead/follow: 36% lead, 64% follow

Portfolio highlights

  • Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.
  • Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
  • Conservio — Discover and Book South Africa's best nature accommodations with Conservio. Book vetted accommodations, easy and safe to book online.
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Life Science VC funding in South Africa at a glance

Stats across 5 deals from 8 investors.

8
investors
in South Africa Life Science startups
5
deals
in South Africa Life Science startups
$2M
median round
in South Africa Life Science startups
38%
lead investors
lead at least one round
40%
Seed
most common funding stage

Access all 8 VC funds in South Africa Life Science startups.

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