Top 15 Biotech VC Funds & Investors in South Africa (June 2026)

Portfolio highlights

• 4QT — Cleantech, Construction, Electrification
• Matta — Matta delivers artificial intelligence software and services for businesses. Offerings include custom model development, data preparation, and API-based deployment across computer vision and language tasks. Tooling covers experiment tracking, evaluation, monitoring, and scalability to move prototypes into production. Services also addressintegration with existing data pipelines, security considerations, and MLOps practices. Engagements include solution design, implementation, and knowledge transfer so internal teams can operate and iterate models over time.
• Rightcharge — Simplify fleet electrification with Rightcharge. The all-in-one platform for automated home reimbursement and public charging cards; all on one bill.

Portfolio highlights

• Novel Farms — Novel Farms uses microbial fermentation to develop cruelty-free, inexpensive and tunable bioscaffolds for the production of cell-based meat products. Novel Farms mission is to craft the taste and texture of the gourmet meats and transform cell-based meat consumption into a sought-after culinary experience for the next generation of consciouseaters.
• Minus — A sustainable coffee alternative, combining the taste, look, and smell of coffee with a smaller footprint to ensure a brighter future for coffee and the planet.
• Unicorn Biotechnologies — Unicorn Biotechnologies is developing a fully automated manufacturing platform to enable cellular agriculture producers to seamlessly scale products from the lab bench to supermarket shelves. Our full stack platform combines hardware, software and analytics to completely automate cellular agriculture manufacturing, reducing costs and increasingproduct quality. By providing a clear path to scale cellular agriculture from grams to tons, we will improve human and planetary health and drive the transition to animal free agriculture.

Portfolio highlights

• Flow — Flow enables automated social media advertising for the real estate industry, providing high volumes of quality property leads and brand building.
• hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.

Portfolio highlights

• 3X4Genetics — Scientifically-robust nutrigenomics (personalised nutrition guided by your own genetic stack). Practitioner education & genomic reporting
• Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling
• SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.

Portfolio highlights

• MPost — MPost means Mobile Post office.It enables any mobile phone user to have his or her phone act like a mobile post office. It allows you to make your mobile number be a formal postal address. With it, you get access to Postal Services through your mobile phone.
• RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
• AURA — A South African cloud-based security and safety startup .

Portfolio highlights

• POW! Foods — Puta en gandia
• Veggie Victory — VeggieVictory is Nigeria’s first plant-based food tech company bringing people a healthier and more sustainable lifestyle through plant-based meats and meals.
• High Time Foods — High Time Foods provides shelf-stable and moldable plant-based meat alternatives to foodservice operators. Their first product is a plant-based chicken alternative that does not require refrigeration. The product is moldable and can be used in any cuisine as a substitute for chicken.

Portfolio highlights

• Phyenti —
• Ancino Technologies —
• Green X Engineering —

Portfolio highlights

• Fixit45 — Fixit45 also provides fleet management, auto parts sourcing and delivery, auto care, refurbishment and upgrades, repair financing, and mechanic workshop software as well as pre-purchase inspections, underlying these with moderation for compliance and accountability.
• Gigmile — Gigmile provides financial services. They provide gig workers with core services and an affordable lease on productive assets that is tailored to their earnings to enable them to succeed in the mobility industry as entrepreneurs.
• HomecomingEx — Homecoming Revolution is a pan-African recruitment firm for global African professionals. We specialise in headhunting & placing global African talent.

Portfolio highlights

• Hive Health — Hive Health is a digital platform that provides access to easy-to-use, affordable, and quality HMO plans for SMEs in the Philippines.
• Inseco — Sustainable insect protein producers, converting organic by-products into nutritious protein. This high in protein product is used in animal feed, pet food, crop production, cosmetics and pharmaceuticals.
• Netbank — Netbank provides various banking solutions like alternative lenders, payment solutions, neobanks, and wallets.

Portfolio highlights

• Vycarb — Vycarb is a Brooklyn-based firm that enables decentralized carbon removal through real-time, autonomous, and direct detection of CO2 in water.
• Plasmaleap —
• Hachiko —

Portfolio highlights

• BioCertica — BioCertica combines advanced genomics technology to interpret your DNA and provide recommendations to unlock a healthy lifestyle.
• Nordic Angels — Join Nordic Angels, the largest investor network in the Nordics, to collaborate, connect, and strengthen the startup ecosystem through exclusive events and resources.

Portfolio highlights

• Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.
• Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
• Conservio — Discover and Book South Africa's best nature accommodations with Conservio. Book vetted accommodations, easy and safe to book online.

Portfolio highlights

• MariHealth Solutions (RF) (PTY) LTD — Proteomics-powered analytics for aquaculture. We quantify 3,000+ proteins per sample to deliver deep biological insights for fish health, nutrition, and farming.

Portfolio highlights

• The Index — The Index is a platform of cutting-edge technology used by clients in the fashion and retail industry to grow their companies and enhance their digital footprints
• De Novo Foodlabs — Producing non-animal dairy proteins using precision fermentation
• Smart Separations — Smart Separations is a limited company based in London UK that has patented an innovative microfiltration technology to produce ceramic filters with self-assembled controllable pores of uniform size in the range between <1 and 50µm. This tight pore size control and range availability will revolutionise the field of MF with a cost-effectiveproduct.It aims to be the world’s leader in MF and particle separations technology – filling the void gap that exists in the market nowadays.

Portfolio highlights

• Opalia — Opalia is introducing a new era of dairy: functional, delicious, and sustainable dairy made from mammary cells.
• Hooked Foods — Leading the transition to a harmless seafood system by serving healthy vegan seafood for everybody to truly enjoy.
• Cultimate Foods — At Cultimate, we are transforming the flavor and aroma industry with natural innovative ingredients.