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Top 50 Health Care VC Funds & Investors in South Africa (October 2026)

The most active venture capital funds investing in South Africa Health Care startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in South Africa Health Care startup companies. Find investors to raise a Pre-Seed, Seed or Series A round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
HAVAÍC
VC Fund
7 South Africa, United States, Kenya Seed, Venture - Series Unknown, Series A Software, Health Care, FinTech $83k–$15M
54 Collective
VC Fund
6 Kenya, Nigeria, South Africa Seed, Pre-Seed Health Care, Information Technology, FinTech $40k–$2M
Launch Africa
VC Fund
4 Nigeria, South Africa, United States Seed, Pre-Seed, Venture - Series Unknown Financial Services, FinTech, Information Technology $200k–$4M
University Technology Fund
VC Fund
4 South Africa Seed, Grant Biotechnology, AgTech, Medical $467k–$5M
Enygma Ventures
VC Fund
3 South Africa, Zambia, Swaziland Seed, Venture - Series Unknown, Pre-Seed Financial Services, Lending, Beauty $150k–$1M
Enso Equity
VC Fund
3 South Africa Seed, Pre-Seed Coffee, EdTech, Medical $321k–$347k
WZ Capital
VC Fund
3 South Africa Seed, Venture - Series Unknown, Pre-Seed Medical, Health Care, Information Technology
Futuregrowth Asset Management
VC Fund
3 South Africa, France, United States Seed, Series A, Series B Software, Transportation, Financial Services $1.8M–$22M
The ASISA ESD Fund
VC Fund
3 South Africa, United States Seed, Venture - Series Unknown, Debt Financing Financial Services, FinTech, Consulting
Growth Grid Venture Capital Partners
VC Fund
3 South Africa Venture - Series Unknown Software, Medical, InsurTech $318k–$1.5M
E4EAfrica
VC Fund
2 South Africa, Germany, Mauritius Seed, Pre-Seed, Series A Internet, Logistics, Supply Chain Management $1M–$8.4M
The Draper Richards Kaplan Foundation
VC Fund
2 United States, India, Kenya Grant, Seed, Venture - Series Unknown Non Profit, Association, Health Care $83k–$3.8M
Naspers Foundry
VC Fund
2 South Africa, United Kingdom Seed, Series A, Series B Financial Services, Software, Farming $989k–$17M
Vumela Fund
VC Fund
2 South Africa, Brazil Seed, Venture - Series Unknown, Debt Financing Education, Hospital, Software $500k–$1.7M
Bose Ventures
VC Fund
2 United States, India, Denmark Venture - Series Unknown, Series B, Series A Software, Health Care, Consumer Electronics $27k–$55M
Ardent Capital
VC Fund
2 Nigeria, Indonesia, Thailand Seed, Pre-Seed, Series A E-Commerce, Internet, Software $100k–$15M
4DX Ventures
VC Fund
2 Egypt, South Africa, United States Seed, Pre-Seed, Series A FinTech, Financial Services, Logistics $50k–$40M
Fireball Capital
VC Fund
2 South Africa, Australia, Nigeria Series A, Venture - Series Unknown, Seed Software, Information Technology, Mobile Apps $473k–$40M
27four Investment Managers
VC Fund
2 South Africa Private Equity, Seed, Secondary Market Health Care, Fitness, Payments
Kaleo Ventures
VC Fund
2 Nigeria, United States, Kenya Pre-Seed, Seed, Series A Financial Services, Information Technology, Software $25k–$15M
Kepple Africa Ventures
VC Fund
2 Nigeria, Kenya, Egypt Seed, Pre-Seed, Series A Financial Services, FinTech, Software $100k–$23M
FINCA Ventures
VC Fund
2 Kenya, Nigeria, United States Seed, Grant, Series A Financial Services, Agriculture, AgTech $40k–$4.2M
Jozi Angels
VC Fund
2 South Africa, Kenya Seed, Pre-Seed, Venture - Series Unknown Health Care, B2B, Apps $188k–$1.6M
Goodwater Capital
VC Fund
2 United States, India, South Korea Seed, Pre-Seed, Venture - Series Unknown Software, FinTech, Financial Services $125k–$105M
Psyence Biomedical
VC Fund
2 South Africa Corporate Round Medical, Health Care, Pharmaceutical $500k–$3.5M
NEXT176
VC Fund
1 South Africa, Hong Kong Seed, Series A, Venture - Series Unknown FinTech, Software, Financial Services $400k–$2.5M
i-Cubed Capital
VC Fund
1 South Africa Seed, Pre-Seed, Private Equity Medical, Health Care, Personal Health $200k–$569k
Norrsken Foundation
VC Fund
1 Nigeria, United States, Rwanda Pre-Seed, Seed, Grant Financial Services, FinTech, Health Care $100k–$4M
SAB Foundation
VC Fund
1 South Africa, India, Brazil Grant, Venture - Series Unknown Health Care, Retail, Farming $89k–$890k
Allan Gray
VC Fund
1 South Africa, United States Seed, Series A, Series C FinTech, Payments, Health Care $563k–$100M
Enza Capital
VC Fund
1 Kenya, Nigeria, South Africa Seed, Series A, Venture - Series Unknown Financial Services, E-Commerce, FinTech $1M–$31M
Bill & Melinda Gates Foundation
VC Fund
1 United States, United Kingdom, India Grant, Series A, Series B Biotechnology, Health Care, Medical $500k–$85M
Five35 Ventures
VC Fund
1 South Africa, Kenya, Egypt Seed, Pre-Seed, Venture - Series Unknown Health Care, Information Technology, FinTech $100k–$4.9M
Foreign, Commonwealth and Development Office
VC Fund
1 Kenya, Mauritius, South Africa Seed, Pre-Seed Social, Medical, Logistics $500k–$790k
PayPal
VC Fund
1 United States, Ireland, United Kingdom Seed, Grant, Venture - Series Unknown FinTech, Financial Services, Software $15k–$100M
AAIC Holdings
VC Fund
1 Nigeria, Togo, Kenya Seed, Series A, Series B Medical, Health Care, Financial Services $1.8M–$40M
Alethea Capital Management
VC Fund
1 United States, South Africa Series A, Seed, Series B Health Care, Biotechnology, Medical $2.5M–$10M
Tofino Capital
VC Fund
1 United States, Nigeria, Egypt Seed, Pre-Seed, Series A Software, Artificial Intelligence, SaaS $100k–$131M
AngelHub Ventures
VC Fund
1 South Africa, Mexico, Colombia Seed, Series A, Pre-Seed Software, Information Technology, Education $300k–$2.3M
Sphere Holdings
VC Fund
1 South Africa Private Equity, Series A Software, Web Apps, Education
PUSH VC
VC Fund
1 Austria, Germany, United States Seed, Pre-Seed, Series A Software, Apps, Health Care $650k–$31M
BYLD
VC Fund
1 United States, United Kingdom, Nigeria Seed, Pre-Seed, Series A Financial Services, Payments, FinTech $120k–$6.5M
Knife Capital
VC Fund
1 South Africa, United States, United Kingdom Series A, Venture - Series Unknown Software, Information Technology, Education $1M–$15M
Raba Partnership
VC Fund
1 United States, South Africa, Egypt Seed, Pre-Seed, Series A Financial Services, FinTech, Finance $600k–$32M
UW Ventures
VC Fund
1 South Africa Seed, Series A FinTech, Payments, Mobile Payments $563k–$31M
LionPride Agility Fund
VC Fund
1 Spain, South Africa Seed Health Care, Internet, Pharmaceutical
Global Founders Capital
VC Fund
1 United States, Germany, United Kingdom Seed, Series A, Pre-Seed Financial Services, Software, FinTech $575k–$30M
Verge HealthTech Fund
VC Fund
1 Estonia, Singapore, United States Seed, Pre-Seed, Series A Health Care, Medical, Medical Device $500k–$4.7M
JPMorgan Chase & Co.
VC Fund
1 United States, Canada, United Kingdom Debt Financing, Post-IPO Debt, Grant Financial Services, Software, Information Technology $400k–$5B
Technology Innovation Agency
VC Fund
1 South Africa Grant, Seed, Pre-Seed Information Technology, Software, Electronics $25k–$1.3M
Access all 175 VC funds in South Africa Health Care startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

HAVAÍC
VC Fund · Cape Town, NA - South Africa, South Africa · 7 investments in South Africa Health Care startups

HAVAÍC is an investment and advisory firm that specialises in early-stage, high-growth African businesses with proven concepts and global prospects, offering investment opportunities to sophisticated investors and international venture capital companies with an interest in Africa. As a complementary offering, HAVAÍC provides corporate advisory andcapital raising services to emerging, internationally scalable businesses.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Seed, Venture - Series Unknown, Series A
  • Geography: South Africa, United States, Kenya

Investor stats

  • Total investments: 49
  • Round size: Seed $83k–$4M; Series A $1.9M–$15M; Venture - Series Unknown $318k–$632k
  • Lead/follow: 65% lead, 35% follow
  • Last fund: Likely still investing — raised $50M in 2024

Portfolio highlights

  • NjiaPay — Payments-as-a-Service platform that will streamline your operations and elevate your online payments across the African continent.
  • SwiftVee — SwiftVEE is a livestock trading mobile app. They support live webcast livestock auctions and silent auctions. Their platform facilitates the discovery and viewing of livestock auctions.They provide webcast advertising, online auctions, and online livestock insurance services and data products for financial institutions.
  • Tanda — As a Tanda Agent, you can sell Kenya's favorite digital products, and grow your duka while you're at it
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54 Collective
VC Fund · Johannesburg, NA - South Africa, South Africa · 6 investments in South Africa Health Care startups

Building and scaling African tech startups with catalytic capital, value-add support and our global network.

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Investment focus

  • Industry: Health Care, Information Technology, FinTech
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 112
  • Round size: Seed $40k–$2M; Pre-Seed $40k–$1.3M
  • Lead/follow: 35% lead, 65% follow

Portfolio highlights

  • Yeah — Yeah is a financial technology company that offers payment processing services while building a credit profile for the banked and unbanked.
  • REasy — Top up locally, pay suppliers globally, and manage international shipments with REasy. Fast, secure, and designed for African businesses expanding worldwide.
  • Konnect — Konnect provides a cross borders payment solution intended to simplify complex financial flows allowing companies of any scale and size to send and receive payments in a practical, secure, and low-cost way.
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Launch Africa
VC Fund · Ebène, Plaines Wilhems, Mauritius · 4 investments in South Africa Health Care startups, 6 in the past 12 months

Launch Africa is a leading Pan-African VC fund solving the significant funding gap in the Seed and pre-Series A investment landscape in Africa

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Investment focus

  • Industry: Financial Services, FinTech, Information Technology
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: Nigeria, South Africa, United States

Investor stats

  • Total investments: 218
  • Round size: Seed $200k–$4M; Pre-Seed $200k–$1.8M; Venture - Series Unknown $200k–$500k
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Zazu — Manza is an all-in-one financial platform for African SMEs, helping businesses manage payments, automate cash flow, and access real-time financial insights from one simple dashboard.
  • Fincart — Fincart is a leading shipping platform in Egypt, connecting your business with top courier services, automating operations, and helping you scale your eCommerce logistics.
  • Udu Technologies — Explore GPU cloud and hardware through AGH Cloud, UduTech's flagship product, and AI advisory for teams in the United States, Africa, the Caribbean and beyond.
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University Technology Fund
VC Fund · Stellenbosch, NA - South Africa, South Africa · 4 investments in South Africa Health Care startups

The University Technology Fund specifically focusses on commercialising technology, intellectual property, and research - Visit Us!

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Investment focus

  • Industry: Biotechnology, AgTech, Medical
  • Stage:Seed, Grant
  • Geography: South Africa

Investor stats

  • Total investments: 25
  • Round size: Seed $484k–$5M; Grant $467k–$473k
  • Lead/follow: 32% lead, 68% follow

Portfolio highlights

  • Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
  • Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
  • Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
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Enygma Ventures
VC Fund · Cape Town, NA - South Africa, South Africa · 3 investments in South Africa Health Care startups

Enygma Ventures is an investment fund for female entrepreneurs and women founders, focused on Southern Africa or SADC. Unlike traditional private equity, venture capital, and banks our team is full of award winning entrepreneurs who understand the same struggles you face first hand.

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Investment focus

  • Industry: Financial Services, Lending, Beauty
  • Stage:Seed, Venture - Series Unknown, Pre-Seed
  • Geography: South Africa, Zambia, Swaziland

Investor stats

  • Total investments: 14
  • Round size: Seed $150k–$1M; Venture - Series Unknown $230k–$457k
  • Lead/follow: 86% lead, 14% follow

Portfolio highlights

  • Pranary — The practical business school for entrepreneurs
  • The Good Mineral — The Good Mineral is award-winning, vegan makeup designed for acne prone, sensitive skin - enjoy natural glowing lightweight coverage - free from preservatives, fragrance, talc, oils, waxes and dyes.
  • PremierCredit Zambia — PremierCredit is an international financial technology company that operates an online microlending and investment platform in Sub-Saharan Africa's emerging markets. The Financial Services Commission (FSC) has licensed and regulated the company, allowing them to provide inclusive financial services throughout Africa.
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Enso Equity
VC Fund · Cape Town, NA - South Africa, South Africa · 3 investments in South Africa Health Care startups

Enso Equity is a venture capital firm that invests in both seed-stage and later-stage companies. They operate in three separate industries, namely private equity, public equity, and private credit.

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Investment focus

  • Industry: Coffee, EdTech, Medical
  • Stage:Seed, Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 5
  • Round size: Seed $321k–$347k
  • Lead/follow: 20% lead, 80% follow

Portfolio highlights

  • Okja — Visit Okja for freshly baked pastries, great coffee and smoothies. Baked fresh in-house every day.
  • Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
  • Reflective Learning — Reflective delivers affordable yet effective Maths and English learning tools to South African classrooms, designed to elevate student achievements
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WZ Capital
VC Fund · 3 investments in South Africa Health Care startups

WZ Capital is a boutique venture capital firm investing in early-stage tech startups.

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Investment focus

  • Industry: Medical, Health Care, Information Technology
  • Stage:Seed, Venture - Series Unknown, Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 6
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Contro — See a licensed online doctor in South Africa for treatment, advice and prescriptions delivered to your door. Fast, private, doctor-guided care with Zapmed.
  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • SigmaX — Math app to help learners&any other ordinary person to better understand math & learn it a fun way. Available on Google play store & via https://t.co/hMzLOv2qXZ
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Futuregrowth Asset Management
VC Fund · Cape Town, NA - South Africa, South Africa · 3 investments in South Africa Health Care startups

Futuregrowth manages the full range of fixed interest and developmental impact funds on behalf of our clients. We are committed to managing and investing our clients' funds in a responsible manner.

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Investment focus

  • Industry: Software, Transportation, Financial Services
  • Stage:Seed, Series A, Series B
  • Geography: South Africa, France, United States

Investor stats

  • Total investments: 22
  • Round size: Seed $1.8M–$5.3M; Series A $3.4M–$11M; Series B $11M–$22M
  • Lead/follow: 68% lead, 32% follow
  • Last fund: May invest from a new fund soon — last raise in 2018

Portfolio highlights

  • CubeSpace — Industry-leading modular attitude determination and control (ADCS) products and solutions. Laser-focused on our customers' success. Your global ADCS partner.
  • Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
  • Happy Pay — Happy Pay is a credit scoring system developing company. The company integrates an autonomous artificial intelligence technology system with the merchant's platform to increase their average basket size and customer conversion metrics, providing users with buy now, and pay later services.
Show all investments...

The ASISA ESD Fund
VC Fund · 3 investments in South Africa Health Care startups

An Invetsment Fund.

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Investment focus

  • Industry: Financial Services, FinTech, Consulting
  • Stage:Seed, Venture - Series Unknown, Debt Financing
  • Geography: South Africa, United States

Investor stats

  • Total investments: 14
  • Lead/follow: 64% lead, 36% follow

Portfolio highlights

  • Pineapple — In short, Pineapple see the traditional insurance model, user journey and products as lacking and set out to remedy these by doing the following: 1) Changing the business model to align incentives, show people how premiums are used and award members leftover premium back 2) Making insuring as easy as snapping a picture where AI does the rest andcover is issued in under 60 seconds 3) Allowing per-item insurance and new product innovation to address cover not currently offered or accessible to manyPineapple launched in South Africa in 2018 with their "My Stuff" per-item insurance and have since launched their auto offering "My Ride". They have also partnered with Travelers in the US and have white-labeled their platform in the US.
  • Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
  • Ngobese And Associates — Ngobese And Associates is a Financial Services providing firm offering brokeraging, advisory and intermediary services.
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Growth Grid Venture Capital Partners
VC Fund · 3 investments in South Africa Health Care startups

Growth Grid Venture Capital Partners

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Investment focus

  • Industry: Software, Medical, InsurTech
  • Stage:Venture - Series Unknown
  • Geography: South Africa

Investor stats

  • Total investments: 5
  • Round size: Venture - Series Unknown $318k–$1.5M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • RecoMed — Find the best doctors and dentists. Search by location or by speciality, and find the right doctor for you.
  • Click2Sure — We provide cloud-based Insurance SaaS solutions for omnichannel distribution, which can save costs & support data-driven decision making. Contact us today.
  • Digital Cabinet — Digital Cabinet makes your business paperless. Security is the topmost priority for the Digital Cabinet, so save time and money with the Digital Cabinet.
Show all investments...

Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

Browse database — It's Free!
E4EAfrica
VC Fund · Cape Town, NA - South Africa, South Africa · 2 investments in South Africa Health Care startups

E4E Africa Backing category-defining emerging market businesses. We invest in businesses that drive economic opportunity and sustainable growth.Learn MoreE4E specializes ... Read More

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Investment focus

  • Industry: Internet, Logistics, Supply Chain Management
  • Stage:Seed, Pre-Seed, Series A
  • Geography: South Africa, Germany, Mauritius

Investor stats

  • Total investments: 27
  • Round size: Seed $1.2M–$7.5M; Pre-Seed $1M–$2M; Series A $1M–$8.4M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: May invest from a new fund soon — last raise in 2020

Portfolio highlights

  • Kuunda — Kuunda provides consulting, liquidity management, data insight tools enabling users to fulfill financial needs through a digital platform.
  • Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
  • Ridge — Ridge structures natural assets into regulated, ISIN-listed financial products accessible through existing banking infrastructure.
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The Draper Richards Kaplan Foundation
VC Fund · Menlo Park, California, United States · 2 investments in South Africa Health Care startups

William H. Draper, III and Robin Richards Donohoe began investing together in the venture industry in 1994 concentrating on building companies in India. Since 1994, they have invested in over one hundred early stage information technology investments both in India and the United States. In 2010, the Foundation joined forces with Robert S. Kaplan,formerly vice-chairman of Goldman Sachs and currently professor of leadership at Harvard Business School. Together the team raised their second fund inviting fourteen innovative philanthropists to join the fund.

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Investment focus

  • Industry: Non Profit, Association, Health Care
  • Stage:Grant, Seed, Venture - Series Unknown
  • Geography: United States, India, Kenya

Investor stats

  • Total investments: 160
  • Round size: Seed $83k–$3.8M; Grant $100k–$1M; Venture - Series Unknown $300k–$3M
  • Lead/follow: 49% lead, 51% follow
  • Last fund: May invest from a new fund soon — raised $65M in 2016

Portfolio highlights

  • Farm to Feed — One third of all food is lost or wasted, enough to feed the number of hungry people twice worldwide. Food loss and waste contributes to 10% of greenhouse gases globally. We aggregate and repurpose imperfect and surplus produce to create a healthier planet.
  • Energiesprong — Energiesprong is a revolutionary, whole house refurbishment and new built standard and funding approach. Mission: scale this approach to international markets.
  • Honeycomb Credit — Grow your business and raise up to $250,000 in crowdfunded community capital from your customers, fans, and local friends.
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Naspers Foundry
VC Fund · Cape Town, NA - South Africa, South Africa · 2 investments in South Africa Health Care startups

Naspers Foundry is a global internet group and invests in technology-based companies. The company believes in the power of local backed by global scale and they look for opportunities to address big societal needs in markets where they see the greatest growth potential.

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Investment focus

  • Industry: Financial Services, Software, Farming
  • Stage:Seed, Series A, Series B
  • Geography: South Africa, United Kingdom

Investor stats

  • Total investments: 19
  • Round size: Seed $989k–$6M; Series A $3.3M–$15M; Series B $2.3M–$17M
  • Lead/follow: 89% lead, 11% follow

Portfolio highlights

  • Planet42 — Having your own car has never been easier. Planet42 is a vehicle rental company offering rent-to-buy car service for private clients.
  • LifeCheq — LifeCheq partners with insurers and advisory firms to deliver AI-enabled distribution, boost adviser productivity, and transform how financial advice is delivered.
  • SweepSouth — Book a home cleaning online from your mobile, tablet or computer. SweepSouth connects you with a cleaner in minutes. Cleaners are experienced, reliable, efficient and insured.
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Vumela Fund
VC Fund · Hyde Park, Newtownabbey, United Kingdom · 2 investments in South Africa Health Care startups

Vumela was established in 2009 by FNB Business Banking and Edge Growth. The objective was to create an innovative model for the development of a sustainable and a financially and operationally independent investment business which invests in high growth small, medium and micro size enterprises with good economic and impact returns.Vumela wascapitalised in 2010. Within the first four years, we’d invested R90 million into eight high growth SMEs, and created a total of 400 jobs. They launched their second fund in 2015, after a further investment of R100 million from FirstRand and R127 million from the Jobs Fund. Within the first year of launching this second fund, we’ve committed R43 million to five investments that are expected to create over 1800 new jobs.The first fund of its kind in South Africa, Vumela’s main goals are to invest in and develop entrepreneurial companies in order to help alleviate poverty in South Africa by creating jobs, and to generate a return for its beneficiaries: the Shalamuka Foundation and the FirstRand Group.

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Investment focus

  • Industry: Education, Hospital, Software
  • Stage:Seed, Venture - Series Unknown, Debt Financing
  • Geography: South Africa, Brazil

Investor stats

  • Total investments: 26
  • Round size: Seed $600k–$910k; Debt Financing $1.1M–$1.7M; Venture - Series Unknown $500k–$1M
  • Lead/follow: 81% lead, 19% follow
  • Last fund: May invest from a new fund soon — raised $20M in 2015

Portfolio highlights

  • Trade Shield — Trade Shield's aim is to increase access to trade credit facilities for those companies that most need them and will benefit the most from them.
  • Breaze Delivery — Optimize your last-mile delivery in SA. Breaze offers same-day delivery, easy Shopify/WooCommerce integration, and live WhatsApp tracking for your brand.
  • Iris Fresh Pty Ltd — Iris Fresh exports fresh produce from Southern Africa to international buyers.
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Bose Ventures
VC Fund · Framingham, Massachusetts, United States · 2 investments in South Africa Health Care startups

Bose Ventures is looking for startups that are pushing the envelope of AR to help build some of these new experiences. They are investing in startups that are developing apps, services, and technology that leverage and extend the Bose AR platform. If you are one of these innovative startups

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Investment focus

  • Industry: Software, Health Care, Consumer Electronics
  • Stage:Venture - Series Unknown, Series B, Series A
  • Geography: United States, India, Denmark

Investor stats

  • Total investments: 24
  • Round size: Series A $1.5M–$10M; Series B $2M–$55M; Venture - Series Unknown $27k–$18M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: May invest from a new fund soon — raised $50M in 2018

Portfolio highlights

  • Vesper — Vesper is an electrical and electronic manufacturing company that specializes in microphones, piezoelectric, and audio. The company is driven by a mission is to deliver voice-powered products to every market, around the world. Vesper was founded in 2009 and headquartered in Boston, Massachusetts.
  • Medrhythms — Pioneering Next-Generation Digital Therapeutics to Improve Walking  
  • Noise — Buy latest Noise smart watches, wireless earbuds, BT neckband earphones, wireless headphones, speakers and smart watch accessories online at best prices in India.
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Ardent Capital
VC Fund · Bangkok, Krung Thep, Thailand · 2 investments in South Africa Health Care startups

Leading Venture Capital & Builder in Southeast Asia | Experts in E-Commerce, B2B, B2C, Fulfilment Startups | Seed, Series A Funding

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Investment focus

  • Industry: E-Commerce, Internet, Software
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Nigeria, Indonesia, Thailand

Investor stats

  • Total investments: 45
  • Round size: Seed $100k–$2.7M; Pre-Seed $100k–$400k; Series A $100k–$15M
  • Lead/follow: 13% lead, 87% follow
  • Last fund: May invest from a new fund soon — raised $13M in 2014

Portfolio highlights

  • Laborhack — LaborHack offers a select network of tested and certified carpenters, plumbers, electricians, masons, welders, and other tradespeople. It provides cleaning, plumbing, electrical, and HVAC services.
  • Trade Lenda — Trade Lenda: Access to Loans, Investments, Utility Payments, Credit Access, Insurance, and More! Unlock Opportunities to Earn, Invest, and Grow. Secure Personal or Business Loans Toda
  • Feather Africa — Feather Africa provides money transaction services, such as enabling users to send and receive money from anyone using the application. It offers withdrawals of cash without ATM cards by sending money to the nearest cash vendors.
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4DX Ventures
VC Fund · Brooklyn, New York, United States · 2 investments in South Africa Health Care startups

4DX Ventures is a Pan-Africa Focused Venture Capital Firm. Our mission is to connect people, ideas, and capital to create a vibrant African community.

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Investment focus

  • Industry: FinTech, Financial Services, Logistics
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Egypt, South Africa, United States

Investor stats

  • Total investments: 99
  • Round size: Seed $456k–$8M; Pre-Seed $50k–$6.5M; Series A $3M–$40M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — raised $49M in 2024

Portfolio highlights

  • Anda Africa — Anda is Angola’s leading mobility fintech platform, providing asset financing, ride hailing, and delivery services to empower mobility entrepreneurs. Built for emerging markets, Anda bridges the credit gap by financing productive assets such as motorcycles, tricycles, and cars, enabling drivers to own their vehicles, increase their earnings, andenter the formal economy. Through technology driven credit profiling and fully digitized payments, Anda creates financial identities for people who were previously underserved and unlocks responsible access to financial services. As an impact driven company, Anda brings together mobility, financing, and digital payments to deliver safe, affordable, and inclusive transportation while enabling a new generation of financially empowered entrepreneurs.
  • Aether Bio — Aether uses its state of the art platform to rapidly engineer enzymes, enabling our customers to manufacture complex and novel products at fractional cost.
  • Aethex — End to end voice agents localized for your market.
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Fireball Capital
VC Fund · Cape Town, NA - South Africa, South Africa · 2 investments in South Africa Health Care startups

Fireball Capital operates as a venture capital firm.

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Investment focus

  • Industry: Software, Information Technology, Mobile Apps
  • Stage:Series A, Venture - Series Unknown, Seed
  • Geography: South Africa, Australia, Nigeria

Investor stats

  • Total investments: 19
  • Round size: Seed $473k–$1M; Series A $5.7M–$40M; Venture - Series Unknown $500k–$4M
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • Plentify — Plentify connects home appliances with cheaper cleaner energy. It does this with an intelligent residential load management platform which matches demand with clean energy supply for 75% cheaper than batteries. Plentify combines advanced hardware, AI, and user-centric design to create smart home products that delight customers while alsostrengthening electricity systems.
  • Immobazyme — Immobazyme provides pioneering the biotechnology industry. Using innovative technologies, along with an environmentally responsible outlook.the company aims to develop an analytical laboratory platform as well as serve the industrial sector through the production of high-value products by organic synthesis and environmental remediationtechnologies.
  • Contactable — Digital Identity Orchestration platform - used extensively by corporates across all sectors for digital onboarding, e-KYC, Self-RICA and identity proofing.
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27four Investment Managers
VC Fund · Johannesburg, NA - South Africa, South Africa · 2 investments in South Africa Health Care startups

27four Investment Managers a leading independent South African-based multi-manager focused on understanding and addressing the evolving needs of retirement funds and individual investors through the provision of unique product solutions and portfolio customisation options. Through ongoing value-add, by way of product differentiation and thedelivery of consistent and superior returns, 27four has earned its position as a leading provider of multi-manager solutions to South African and international investors.

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Investment focus

  • Industry: Health Care, Fitness, Payments
  • Stage:Private Equity, Seed, Secondary Market
  • Geography: South Africa

Investor stats

  • Total investments: 5
  • Lead/follow: 40% lead, 60% follow

Portfolio highlights

  • Ctrack — Ctrack is the vehicle tracking provider with more than 24 years' experience of developing effective fleet solutions. Ctrack is a part of DigiCore Holdings, a global company listed on the Johannesburg Stock Exchange, whose advanced Ctrack technology is fitted to almost 430,000 vehicles operating in 32 countries across 5 continents.
  • Peach Payments — Get Peach as your Payment Gateway and Grow your ecommerce. Process online payments with Visa, Mastercard, Debit Orders, EFT payments, and subscriptions. Plugins for Wix, Shopify, WooCommerce.
  • Barracuda Holdings — Barracuda Holdings (Pty) Ltd. is an owner-driven company established in 2010 by the founding partners, each of whom has over 20 years of experience. Barracuda Holdings provides manufacturing expertise across multiple sectors, including Automotive accessories, diagnostic tools, and fleet management.
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Kaleo Ventures
VC Fund · Dubai, Dubai, United Arab Emirates · 2 investments in South Africa Health Care startups

Kaleo Ventures is an investment firm prefers to invest in early-stage companies across Africa.

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Investment focus

  • Industry: Financial Services, Information Technology, Software
  • Stage:Pre-Seed, Seed, Series A
  • Geography: Nigeria, United States, Kenya

Investor stats

  • Total investments: 58
  • Round size: Seed $25k–$2.7M; Pre-Seed $100k–$1M; Series A $100k–$15M
  • Lead/follow: 7% lead, 93% follow
  • Last fund: Likely still investing — raised $1.1M in 2024

Portfolio highlights

  • BankWise — Liga123 merupakan situs slot jackpot 888 slots paling gacor dan juga platform ini terdata paling banyak dicari hari ini karena memiliki akses yang mudah tanpa harus menggunakan Apk tambahan seperti VPN untuk memainkan game favorit.
  • ChipMango — ChipMango is a semiconductor company that provides chip design and pre-manufacturing engineering services.
  • Aeon Cyber Defense — Aeon is a cybersecurity company focused on securing cloud, code, runtime, and AI environments.
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Kepple Africa Ventures
VC Fund · Tokyo, Tokyo, Japan · 2 investments in South Africa Health Care startups

Kepple Africa Ventures is an early-stage venture capital firm.

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Investment focus

  • Industry: Financial Services, FinTech, Software
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Nigeria, Kenya, Egypt

Investor stats

  • Total investments: 85
  • Round size: Seed $500k–$4.5M; Pre-Seed $100k–$3.4M; Series A $1.1M–$23M
  • Lead/follow: 21% lead, 79% follow

Portfolio highlights

  • Chari — Chari is an e-commerce and fintech app for traditional retailers in French-Speaking Africa allowing them to order any consumer goods they sell and get delivered for free in less than 24 hours. Chari is also a financial services provider for these retailers, offering them microloans
  • Intmax — INTMAX has developed significant innovations in ZK implementation making it a unique Layer2 rollup network that offers low cost, security, tunable privacy, and above all, scalability.
  • TIBU Health — TIBU Health is a disruptive HealthTech logistics company that provides high-quality healthcare services.
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FINCA Ventures
VC Fund · Washington, District of Columbia, United States · 2 investments in South Africa Health Care startups

FINCA Ventures is an impact investing initiative of FINCA International that provides patient capital and support to early-stage social enterprises.

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Investment focus

  • Industry: Financial Services, Agriculture, AgTech
  • Stage:Seed, Grant, Series A
  • Geography: Kenya, Nigeria, United States

Investor stats

  • Total investments: 32
  • Round size: Seed $1.1M–$4M; Grant $40k–$100k; Series A $1.1M–$4.2M
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Cladfy — Cladfy is a data analytics company that creates tools to assist lenders, merchants, and individuals in making informed loan, savings, and expenditure decisions.
  • Karpolax — Offering innovative fruit preservation products! For the grower, the packer, and the retailer.
  • Affinity — Join over 145,000 who trust the Affinity to manage their personal and business banking needs, from payments to savings, as well as loans
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Jozi Angels
VC Fund · Johannesburg, NA - South Africa, South Africa · 2 investments in South Africa Health Care startups

Jozi Angels is an angel network based in Johannesburg, South Africa. We exist to grow the startup ecosystem and facilitate the growth of innovative startups.

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Investment focus

  • Industry: Health Care, B2B, Apps
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: South Africa, Kenya

Investor stats

  • Total investments: 11
  • Round size: Seed $200k–$1.6M; Pre-Seed $188k–$1M
  • Lead/follow: 9% lead, 91% follow

Portfolio highlights

  • Jahazii — Jahazii helps employers offer on-demand access to earned wages, giving employees financial flexibility without loans while reducing pressure on HR and payroll teams. Funds on M-PESA in seconds, at no cost to you.
  • TUNL — Ship globally with ease. TUNL offers affordable, transparent international shipping built for South African brands. Up to 91% cheaper. No surprises.
  • The Awareness Company — We use data to tell stories that are useful to humans.
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Goodwater Capital
VC Fund · Burlingame, California, United States · 2 investments in South Africa Health Care startups

Consumer Tech Investors - We empower exceptional entrepreneurs everywhere to change the world for good.

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Investment focus

  • Industry: Software, FinTech, Financial Services
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: United States, India, South Korea

Investor stats

  • Total investments: 913
  • Round size: Seed $850k–$7.5M; Pre-Seed $125k–$2.1M; Venture - Series Unknown $481k–$105M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: Likely actively investing — fresh fund, raised $5M in 2025

Portfolio highlights

  • Kaon — Discover prompts and AI apps built by a global community, or publish your own. FlowGPT is an open platform for building and sharing with AI.
  • Pure — Pure Poker is a privately held fintech and software company that develops a legal, compliant, rake-free real-money online poker platform. Headquartered in San Francisco, California, the company replaces the traditional casino "house" model with a trusted, identity-verified social gaming network.
  • Wrtn Technologies — Bring AGI Close to People
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Psyence Biomedical
VC Fund · Toronto, Ontario, Canada · 2 investments in South Africa Health Care startups

Psyence Biomedical, therapeutic division of Psyence Group Inc which develops natural psilocybin products for palliative care.

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Investment focus

  • Industry: Medical, Health Care, Pharmaceutical
  • Stage:Corporate Round
  • Geography: South Africa

Investor stats

  • Total investments: 2
  • Round size: Corporate Round $500k–$3.5M
  • Lead/follow: 100% lead, 0% follow

Portfolio highlights

  • PsyLabs — Licensed Cultivation and Production Facility - International Supplier of Pharmaceutical Grade Psychoactive Compounds
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NEXT176
VC Fund · 1 investments in South Africa Health Care startups

Creating disruptive and sustainable businesses to positively impact 1 Billion lives.

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Investment focus

  • Industry: FinTech, Software, Financial Services
  • Stage:Seed, Series A, Venture - Series Unknown
  • Geography: South Africa, Hong Kong

Investor stats

  • Total investments: 7
  • Round size: Seed $400k–$2.5M
  • Lead/follow: 43% lead, 57% follow

Portfolio highlights

  • Pumpkn — Need reliable funding? We provide quick loans and capital tailored for Agriculture businesses in South Africa. Grow your business with Pumpkn. Apply now!
  • Jem — We give employers the ability to send company-wide communications, deliver payslips, manage leave & give employees access to their earnings, via WhatsApp.
  • The Awareness Company — We use data to tell stories that are useful to humans.
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i-Cubed Capital
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

i-Cubed Capital provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retiremen, including savings plans with tax incentives.i-Cubed provide a bouquet of funds for clients, ranging from unit trusts to investment funds for retirement, including savings plans with tax incentives. We assess fund managerperformances by reviewing fact sheets and provide our clients with a variety of options to meet their investment objectives.

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Investment focus

  • Industry: Medical, Health Care, Personal Health
  • Stage:Seed, Pre-Seed, Private Equity
  • Geography: South Africa

Investor stats

  • Total investments: 4
  • Round size: Pre-Seed $200k–$569k
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Yebo Fresh — Yebofresh is a new online shopping service, delivering popular groceries straight into areas that are generally unserved by most formal retailers. Our unique business model and partnerships with manufacturers allow us to deliver top quality products and A-brands at extremely competitive prices. Yebofresh serves Imizamo Yethu, Langa, Khayelitsha,Mfuleni and Gugulethu and following recent seed funding, is rapidly expanding across the greater Cape Town area.
  • Cape Doctors — CA Cape Doctors is a trusted private medical practice in Cape Town dedicated to providing high-quality primary healthcare services for individuals and families. With modern facilities located in Rondebosch and Claremont, the practice offers convenient access to professional medical care in a welcoming and patient-focused environment. Theexperienced team of doctors and healthcare professionals are committed to delivering safe, reliable, and comprehensive treatment for a wide range of medical needs.The practice provides a full spectrum of general practitioner services, including routine medical consultations, health screenings, chronic disease management, and treatment for acute illnesses. Patients can also access services such as blood tests, pathology, X-rays, minor procedures, and medical examinations for travel or visa requirements. CA Cape Doctors focuses on preventative healthcare, early diagnosis, and personalised treatment plans to help patients maintain long-term health and wellbeing.With flexible appointment scheduling, online booking options, and availability on weekends and public holidays, CA Cape Doctors aims to make quality healthcare accessible and convenient. The practice combines modern medical technology with compassionate care, ensuring that every patient receives professional attention and support tailored to their individual health needs.
  • NewForm Foods — We are leveraging a continent-spanning R&D network to help food producers develop and scale cultivated animal products, fast & affordably.
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Norrsken Foundation
VC Fund · Stockholm, Stockholms Lan, Sweden · 1 investments in South Africa Health Care startups

Norrsken Foundation is non-profit organization solving problems such as poverty, famine, environmental issues and mental health.

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Investment focus

  • Industry: Financial Services, FinTech, Health Care
  • Stage:Pre-Seed, Seed, Grant
  • Geography: Nigeria, United States, Rwanda

Investor stats

  • Total investments: 19
  • Round size: Seed $100k–$4M; Pre-Seed $125k–$1.1M
  • Lead/follow: 21% lead, 79% follow

Portfolio highlights

  • RYE — RYE is a members-only, low-cost green energy supplier built for businesses with no time to deal with energy suppliers. Always accurate energy or it's free
  • Eden Care Medical — Eden Care Medical is a mobile application that provides medical and health insurance as well as financial services.
  • ORDA — Process orders, accept payments, connect to logistic providers, engage with your customers + more. We equip you with everything you need to grow your business.
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SAB Foundation
VC Fund · Gauteng, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

The SAB Foundation invests in entrepreneurs and social innovation. Its priority focus in on businesses and innovations that benefit women and youth, people in rural areas and people living with a disability.

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Investment focus

  • Industry: Health Care, Retail, Farming
  • Stage:Grant, Venture - Series Unknown
  • Geography: South Africa, India, Brazil

Investor stats

  • Total investments: 9
  • Round size: Grant $89k–$890k
  • Lead/follow: 67% lead, 33% follow

Portfolio highlights

  • Respo — Respo is a provider of comprehensive emergency response solutions, leveraging innovative technology and strategic partnerships to deliver timely and response.
  • The Marking App — The Marking App provides a data-free application that automatically marks handwritten school assessments while also automating school administration.
  • Word Of Mouth — Word of Mouth is a South African social enterprise (NPC), with a digital marketplace for informal economy workers to connect and trade with local customer from their community.
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Allan Gray
VC Fund · Alfred, New York, United States · 1 investments in South Africa Health Care startups

Allan Gray is Africa's largest privately owned investment management company focused on generating long-term wealth for investors..

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Investment focus

  • Industry: FinTech, Payments, Health Care
  • Stage:Seed, Series A, Series C
  • Geography: South Africa, United States

Investor stats

  • Total investments: 15
  • Round size: Seed $563k–$4M; Series A $1.3M–$31M; Series C $70M–$100M
  • Lead/follow: 20% lead, 80% follow

Portfolio highlights

  • onafriq — MFS Africa is the largest mobile money inter-operability hub in Africa, which connects mobile network operators across the continent through a single API. In addition to mobile remittance services, the MFS Africa API enables merchant payment, bulk payment, bank-to-wallet transfers, and an array of other cross border digital payments services.
  • Sendmarc — Manage your organization's DMARC, SPF, and DKIM with world-class implementation services and support. All in one easy-to-use platform.
  • Peach Payments — Get Peach as your Payment Gateway and Grow your ecommerce. Process online payments with Visa, Mastercard, Debit Orders, EFT payments, and subscriptions. Plugins for Wix, Shopify, WooCommerce.
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Enza Capital
VC Fund · Nairobi, Nairobi Area, Kenya · 1 investments in South Africa Health Care startups

Venture investor in high-growth Founders and Teams using technology to solve large and meaningful problems across Africa

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Investment focus

  • Industry: Financial Services, E-Commerce, FinTech
  • Stage:Seed, Series A, Venture - Series Unknown
  • Geography: Kenya, Nigeria, South Africa

Investor stats

  • Total investments: 53
  • Round size: Seed $1M–$8M; Series A $3.6M–$31M; Venture - Series Unknown $2.6M–$17M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — raised $58M in 2023

Portfolio highlights

  • Yakeey — Yakeey is an end-to-end transactional marketplace that radically simplifies the experience of buying, selling and renting real estate.We leverage on data and technology to connect all real estate market players through a state of the art platform, create a chain of trust and powerful network effects and accelerate transactions.Yakeey is builton a community of real estate advisors, YakeeyPRO, to deliver a continuous professional and tailored service at every step of the transaction.
  • Orca Fraud — Orca empowers fraud fighters with effective tools to combat fraud
  • Aethex — End to end voice agents localized for your market.
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Bill & Melinda Gates Foundation
VC Fund · New York, New York, United States · 1 investments in South Africa Health Care startups

We are a nonprofit fighting poverty, disease, and inequity around the world

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Grant, Series A, Series B
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 408
  • Round size: Grant $500k–$15M; Series A $5M–$60M; Series B $7.2M–$85M
  • Lead/follow: 76% lead, 24% follow
  • Last fund: May invest from a new fund soon — raised $50M in 2017

Portfolio highlights

  • SeamlessHR — Africa's Leading HR & Payroll Software - Empowering African Businesses for Productivity and Profitability Through Technology.
  • AN2 Therapeutics — AN2 Therapeutics develops breakthrough medicines through our boron chemistry platform, advancing therapies for infectious diseases and cancer worldwide.
  • Readily Diagnostics — Readily Diagnostics develops speedy and accurate diagnostic tests for respiratory disorders, enabling faster and more effective therapy at the point of care.
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Five35 Ventures
VC Fund · Gauteng, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

Five35 Ventures is committed to unlocking capital and growth opportunities for female-focused early-stage African technology startups.

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Investment focus

  • Industry: Health Care, Information Technology, FinTech
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: South Africa, Kenya, Egypt

Investor stats

  • Total investments: 21
  • Round size: Seed $100k–$2.8M; Pre-Seed $100k–$1.7M; Venture - Series Unknown $200k–$4.9M
  • Lead/follow: 14% lead, 86% follow

Portfolio highlights

  • Susu — Susu is a dynamic and innovative company that offers a wide range of health services for families in the African diaspora. Susu provides a complete offer on Preventive care, Medical treatments, Management of chronic diseases, and Authentic drugs.
  • Kasha — Health products and household goods you want, delivered to where you are.
  • Fincart — Fincart is a leading shipping platform in Egypt, connecting your business with top courier services, automating operations, and helping you scale your eCommerce logistics.
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Foreign, Commonwealth and Development Office
VC Fund · London, England, United Kingdom · 1 investments in South Africa Health Care startups

Foreign & Commonwealth Office is a government organization that provides tourists and travellers with travel alerts, tips, and advice. It promotes the United Kingdom's interests overseas supporting its citizens and businesses around the globe.Foreign & Commonwealth Office has a worldwide network of embassies and consulates thatemploys over 14,000 people in nearly 270 diplomatic offices. It works with international organizations to promote British interests and global security, including the EU, NATO, Foreign & Commonwealth Office was founded on January 1, 1936 and is based in London, United Kingdom.

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Investment focus

  • Industry: Social, Medical, Logistics
  • Stage:Seed, Pre-Seed
  • Geography: Kenya, Mauritius, South Africa

Investor stats

  • Total investments: 4
  • Round size: Seed $500k–$790k
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Ziada — Ziada is a mobile application that connects you to service providers near you and vice versa. Download Ziada today from the Google Playstore to start experiencing convenience.
  • HealthDart — Consult with a doctor, nurse or pharmacist, order medicines or get health advice - at a price you can afford
  • Keep IT Cool — Raino Tech4Impact is a social enterprise that leverages technology as an enabler to empower African communities. We have been deploying technology-driven solutions in agriculture and health, powered by renewable energy to achieve sustainability.
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PayPal
VC Fund · San Jose, California, United States · 1 investments in South Africa Health Care startups

PayPal has remained at the forefront of the digital payment revolution for more than 20 years. By leveraging technology to make financial services and commerce more convenient, affordable, and secure, the PayPal platform is empowering more than 375 million consumers and merchants in more than 200 market to join and thrive in the global economy.

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Investment focus

  • Industry: FinTech, Financial Services, Software
  • Stage:Seed, Grant, Venture - Series Unknown
  • Geography: United States, Ireland, United Kingdom

Investor stats

  • Total investments: 48
  • Round size: Seed $45k–$18M; Grant $15k–$117k; Venture - Series Unknown $28M–$100M
  • Lead/follow: 35% lead, 65% follow

Portfolio highlights

  • RICE — RCIE is a co-working ecosystem that connects entrepreneurs to a customized curriculum, corporate partners, and access to capital. It is designed to connect the next generation of multi-cultural and women entrepreneurs to the tools and relationships required to turn dreams into reality.The company was founded in 2016 and is headquartered inAtlanta, Georgia.
  • PopID — PopID offers a facial recognition platform that enables users to authenticate identity and process payments through biometric verification. Its core service, PopPay, allows customers to link their facial image to a payment method, facilitating transactions at participating businesses without the need for physical cards or mobile devices. The systemsupports various retail formats, including kiosks, drive-thrus, and counter services, and integrates with loyalty programs to personalize the customer experience. PopID's technology has been adopted by merchants such as Whataburger and Steak 'n Shake, aiming to streamline ordering and checkout processes. The company emphasizes user consent and data security, storing encrypted biometric data and allowing users to opt-in or out at their discretion. PopID has also expanded internationally, partnering with entities like SoftBank's Japan Computer Vision to introduce its services in markets such as Japan.
  • Shopware — Shopware is a trendsetting ecommerce platform to power your online business. Our ecommerce solution offers the perfect combination of beauty & brains you need to build and customize a fully responsive online store.
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AAIC Holdings
VC Fund · Singapore, Central Region, Singapore · 1 investments in South Africa Health Care startups

AAIC Holdingsis engages in nurturing investments in emerging countries, consulting and M&A, management outsourcing and human capital.

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Investment focus

  • Industry: Medical, Health Care, Financial Services
  • Stage:Seed, Series A, Series B
  • Geography: Nigeria, Togo, Kenya

Investor stats

  • Total investments: 10
  • Round size: Seed $1.8M–$2.6M; Series A $5M–$10M; Series B $30M–$40M
  • Lead/follow: 30% lead, 70% follow

Portfolio highlights

  • BIMA — BIMA is an insurtech player using mobile technology to provide insurance and health services to emerging markets. To serve its customers, the company has developed a proprietary technology platform, established exclusive partnerships with mobile operators, and built relationships with international insurers. BIMA utilizes its technology platform toserve customers in 13 countries across Asia, Africa, and Latin America and has reached to date 31 million subscribers.
  • CrowdForce — CrowdForce is an offline distribution network for market research and financial services. The company empowers businesses to drive mass adoption of digital, crypto, and financial services through the use of mobile technology to help businesses, banks, digital wallets, multinational organizations, NGOs, and government agencies to reach theunderserved population in their communities.CrowdForce was founded in 2016 and is headquartered in San Francisco, California.
  • Helium Health — Helium Health empowers healthcare providers in Africa with digital tools, financing solutions, and data partnerships. Learn more about our innovative solutions.
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Alethea Capital Management
VC Fund · Rancho Santa Fe, California, United States · 1 investments in South Africa Health Care startups

Alethea Capital Management is an SEC-registered investment advisor founded in March of 2011. As an investment management and research firm, the mission of Alethea is simple – to provide the highest level of service and guidance to our clients with honesty, integrity, and transparency. The firm’s services include fee-based asset management,research/advanced quantitative systematization, manager/strategy evaluation, and comprehensive planning. Alethea’s center of operations is in San Diego, CA.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Seed, Series B
  • Geography: United States, South Africa

Investor stats

  • Total investments: 8
  • Round size: Series A $2.5M–$10M
  • Lead/follow: 50% lead, 50% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2019

Portfolio highlights

  • PatientPartner — Discover PatientPartner, the leading patient engagement software transforming pharma and med-tech with scalable, data-driven solutions that drive better health outcomes.
  • Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling
  • SEngine Precision Medicine — The Search Engine For Identifying Personalized Cancer Treatments.
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Tofino Capital
VC Fund · Washington, District of Columbia, United States · 1 investments in South Africa Health Care startups

Tofino Capital is an early stage investor in emerging market technology companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Nigeria, Egypt

Investor stats

  • Total investments: 25
  • Round size: Seed $150k–$22M; Pre-Seed $100k–$1M; Series A $25M–$131M
  • Lead/follow: 12% lead, 88% follow
  • Last fund: Likely still investing — raised $10M in 2022

Portfolio highlights

  • Vultron — Compress proposal production timeframes from weeks into days with Generative AI.
  • Terra Industries — Terra Industries develops autonomous security systems and software platforms that support the monitoring and protection of physical assets, infrastructure, and operational environments across land, air, and maritime domains. The company provides unmanned vehicles, autonomous towers, and sensor-based surveillance hardware that collect and transmitdata for continuous situational awareness. Its software layer, built around an integrated operating system, processes sensor inputs, applies artificial intelligence models, and coordinates automated responses to detected events. Terra Industries designs its systems to support functions such as perimeter security, infrastructure monitoring, asset tracking, and threat detection within complex operational settings. The company’s platforms enable operators to manage multiple autonomous devices through a unified interface that supports mission planning, data visualization, and system control. Its technology is used by organizations that require coordinated security, monitoring, and response capabilities for facilities, remote sites, and distributed operations.
  • Irreversible — Irreversible designs next-generation analog AI chips that enable meaningful intelligence anywhere — from sensors to robots.
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AngelHub Ventures
VC Fund · Stellenbosch, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

Operating out of Stellenbosch in South Africa and backed by two family offices Angelhub Ventures's team is passionate about early stage investments in (South) Africa. Being entrepreneurial ourselves, we thoroughly understand the challenges and changes our founders face – which is why we back them in any way we can. Most importantly, we believein building great businesses and we are in it for the long haul.

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Investment focus

  • Industry: Software, Information Technology, Education
  • Stage:Seed, Series A, Pre-Seed
  • Geography: South Africa, Mexico, Colombia

Investor stats

  • Total investments: 14
  • Round size: Seed $2M–$2.3M; Series A $300k–$1.7M
  • Lead/follow: 71% lead, 29% follow
  • Last fund: May invest from a new fund soon — last raise in 2014

Portfolio highlights

  • Motai —
  • Syscap — Syscap is a financial technology company that offers cutting-edge solutions to financial institutions to have a better administration and management of their funding sources. It connects the leaders of financial and real estate institutions with their funders. For institutions, the company ensures the optimization of their funding source managementprocesses, but also the strengthening of the relationship with their funders. To funders, Syscap guarantees the transparency and timely monitoring of its funds for the safety and growth of its resources.
  • Velocity — Velocity is a micro fulfillment dark store that delivers through digital channels.
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Sphere Holdings
VC Fund · Sandston, Virginia, United States · 1 investments in South Africa Health Care startups

Founded in 2003, Sphere is a high performing investment holding company driven to create value for funders, shareholders and business partners. With a solid track record shaped over a decade, They actively seek out investment partnerships with high quality privately owned businesses across a range of strategic sectors.Their success is drivenby an experienced team, Their own capital, a disciplined investment process, and broad business networks. Passionate about partnerships, They commit for the long term and actively work with Their portfolio companies to build great businesses.Majority black controlled and managed and boasting 71% black ownership, including 31% women ownership, Sphere has the necessary credentials to advance the broad based Black Economic Empowerment goals of South African businesses. As the focus turns to the rest of the continent, They actively support Their investments in their pan-African ambitions.Their strong belief in the principles of broad based empowerment means that approximately 15% of the shares in Sphere are held by charitable organisations. Over the years, more than five million worthy beneficiaries in nine provinces across South Africa have benefited from Their track record of delivery.

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Investment focus

  • Industry: Software, Web Apps, Education
  • Stage:Private Equity, Series A
  • Geography: South Africa

Investor stats

  • Total investments: 3
  • Lead/follow: 67% lead, 33% follow
  • Last fund: May invest from a new fund soon — raised $40M in 2006

Portfolio highlights

  • hearX Group — hearX is an award-winning start-up with the mission of providing affordable access to hearing healthcare using smart digital solutions. With a strong research and engineering background, we aim to democratize and decentralize hearing care, obliterating the traditional audiology model and market, which was never built to scale, instead providinghearing care to millions by leveraging our smart tech, big data and artificial intelligence expertise.The hearX Group four categories of solutions: Lead Generation and Remote Care solutions, Clinical solutions, Preventative Solutions as well as Direct to Consumer intervention solutions.We have had more than 1 000 000 tests and screenings done using our products across 39 countries. Our innovative solutions are as accurate, but faster, cheaper and easier to use than traditional methods. We pride ourselves in offering a fully managed service, providing an entirely new way to overcome traditional barriers to the detection and diagnosis of disabling hearing loss.
  • Pearson South Africa — Pearson is the world's leading education company. With a presence in over 70 countries and 40 000 employees, Pearson provides learning solutions from early childhood learning to professional certification, Pearson curriculum-based materials, e-learning content and tools, as well as teacher training and testing programmes help to educatemillions of people worldwide.Pearson is also a leading provider of digital learning programmes and test development, processing and scoring services to educational institutions, corporations and professional bodies around the world.In order to provide unique learning solutions, Pearson creates content, technology, assessment tools and services.Partnering with stakeholders, Pearson creates innovative solutions to improve learner achievement and institutional effectiveness.South Africa’s best-known and most-respected names in publishing; Longman, Heinemann and Maskew Miller were merged to form Pearson South Africa in 2010. In 2013 alone, Pearson distributed over 23 million text books into schools across South Africa, and trained over 80 000 teachers. All this content is being converted into e-content.
  • Babcock International Group - Africa — Babcock International Group - Africa is manages critically important assets that help to bring power to our homes and businesses.
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PUSH VC
VC Fund · Vienna, Wien, Austria · 1 investments in South Africa Health Care startups

We are an early-stage Venture Capital Firm investing in outstanding teams with convincing products and high growth potential.

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Investment focus

  • Industry: Software, Apps, Health Care
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Austria, Germany, United States

Investor stats

  • Total investments: 46
  • Round size: Seed $650k–$8.1M; Series A $5M–$31M
  • Lead/follow: 17% lead, 83% follow
  • Last fund: May invest from a new fund soon — raised $11M in 2019

Portfolio highlights

  • Voltrac — Building electric autonomous vehicles for farming & frontline logistics
  • enspired — Revolutionize battery storage with AI-powered BESS optimization. Our energy trading platform ensures smart, real-time market access. Contact us today!
  • Aitiologic — A precision medicine startup providing multi-modal liquid biopsy solutions for early disease detection and targeted therapy.
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BYLD
VC Fund · London, England, United Kingdom · 1 investments in South Africa Health Care startups

Byld Ventures is a corporate venture capital firm focusing on early-stage technology investments.

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Investment focus

  • Industry: Financial Services, Payments, FinTech
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, United Kingdom, Nigeria

Investor stats

  • Total investments: 25
  • Round size: Seed $200k–$6.5M; Pre-Seed $120k–$2.1M
  • Lead/follow: 12% lead, 88% follow

Portfolio highlights

  • Munify — Fast, secure, and cost-efficient cross-border payments powered by stablecoins. Send and receive money globally without delays, high fees, or the complexity
  • Bluerails — Payment infrastructure for the agentic economy. Get found, acted on, and paid by AI agents. Agent-ready checkout, global settlement, and compliance built in.
  • Stream — Stream is a company that helps make payments simpler, faster, and reliable.
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Knife Capital
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

Knife Capital is an independent growth equity investment firm focusing on innovation-driven ventures with proven traction. By leveraging knowledge, networks & funding, Knife accelerates the international expansion of entrepreneurial businesses that achieved a product/market fit in a beachhead market. Knife have offices in Cape Town andLondon.Knife invests via a consortium of funding partnerships, including SARS section 12J Venture Capital Company KNF Ventures and select family offices. Knife facilitated lucrative exits of local technology companies to the likes of General Electric, Visa, Garmin and Uber.

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Investment focus

  • Industry: Software, Information Technology, Education
  • Stage:Series A, Venture - Series Unknown
  • Geography: South Africa, United States, United Kingdom

Investor stats

  • Total investments: 40
  • Round size: Series A $2M–$15M; Venture - Series Unknown $1M–$2M
  • Lead/follow: 70% lead, 30% follow
  • Last fund: Likely still investing — raised $50M in 2022

Portfolio highlights

  • wamly — Wamly is the recruitment software, It has given us time back to focus on transformational work.
  • Cue — Cue is one customer service platform for live chat, chatbots and broadcasts across WhatsApp, Messenger, web chat, email and many other digital channels.
  • Optique Optometrists — Optique Optometrists provides comprehensive eye care services, including eye tests, prescription glasses, and contact lenses. The company offers affordable eye care solutions and has multiple branches across South Africa. Customers can book appointments online and access a wide range of eyewear options. Optique Optometrists focuses on deliveringquality vision care and ensuring customer satisfaction through professional services and convenient booking options.
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Raba Partnership
VC Fund · Cape Town, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

The Raba Partnership, Raba Capital, Raba

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Investment focus

  • Industry: Financial Services, FinTech, Finance
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, South Africa, Egypt

Investor stats

  • Total investments: 59
  • Round size: Seed $600k–$6M; Pre-Seed $635k–$6.5M; Series A $10M–$32M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely still investing — raised $60M in 2021

Portfolio highlights

  • Thndr — Egypt's #1 investing platform by active users. Stocks, gold and mutual funds in one app, licensed and regulated by the FRA. Start with what you have.
  • Ezeebit — Ezeebit is a payment solutions provider that enables African merchants to accept cryptocurrency payments both in-store and online. The platform processes transactions quickly and automatically converts the cryptocurrency into stablecoins to eliminate volatility risk. Funds are then settled into the merchant's local currency account, typicallySouth African Rand (ZAR), on the next business day. The company offers multi-currency support for popular cryptocurrencies like Bitcoin and Ethereum and maintains compliance with financial regulatory bodies.
  • Letly — Letly is developing an AI‑driven platform for the rental property market that automates tasks related to managing rental listings and tenant interactions. It aims to use intelligent agents to handle tasks such as scheduling viewings, responding to inquiries, and optimizing property management workflows. The platform is currently in a waitlistphase, signaling ongoing development and private access only.
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UW Ventures
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

UW is a multi-stage investor that provides growth and replacement capital across the equity-cycle. Its activities span from high-growth venture to mid-market private equity opportunities.

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Investment focus

  • Industry: FinTech, Payments, Mobile Payments
  • Stage:Seed, Series A
  • Geography: South Africa

Investor stats

  • Total investments: 20
  • Round size: Seed $563k–$2.5M; Series A $1.3M–$31M
  • Lead/follow: 35% lead, 65% follow

Portfolio highlights

  • Pargo — Pargo is a convenient logistics solution that lets you collect and return parcels at Pargo parcel points throughout the country when it suits you best.
  • Rather.chat — Rather.chat offers a platform that facilitates meaningful connections between businesses and their customers through WhatsApp. This service is designed to make customer interactions more personal and efficient, allowing for real-time communication. By leveraging the widespread use of WhatsApp, Rather.chat aims to enhance the customer serviceexperience, making it easier for businesses to address inquiries, resolve issues, and maintain engagement with their audience. The focus is on creating a seamless bridge for dialogue that respects the convenience and preferences of the modern consumer, who increasingly favors instant messaging over traditional forms of communication.
  • Manholes 4 Africa — m4a (Pty) Ltd specializes in the manufacturing of composite and plastics products designed for the utilities networks industry. As an Original Equipment Manufacturer (OEM), the company offers a comprehensive range of products including access chambers, microducts, bundled microducts (multiducts), sub ducts, corrugated pipes, axsCHAMBERS™,cnktCLOSURES™, fibreDUCT™, and fibreCABLE™. These products cater to the telecommunications sector, providing end-to-end solutions for infrastructure needs. m4a (Pty) Ltd is recognized for its innovative approach in developing polymer and composite civil infrastructure solutions. The company holds ISO9001 certification, ensuring high standards in quality management systems.
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LionPride Agility Fund
VC Fund · Johannesburg, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

Lionpride Investment Holdings is a premier South African impact investment firm focused on driving sustainable economic returns and social impact. Our experienced team partners with high-growth businesses, utilizing private equity and venture capital to invest today for a better tomorrow.

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Investment focus

  • Industry: Health Care, Internet, Pharmaceutical
  • Stage:Seed
  • Geography: Spain, South Africa

Investor stats

  • Total investments: 2
  • Lead/follow: 50% lead, 50% follow

Portfolio highlights

  • BusyMed — BusyMed connects independent local pharmacists to their communities using the BusyMed App. Get your medication delivered to your door in 60 minutes. Shop. Pay. Delivered.
  • Docline — Connecting Patients with Doctors
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Global Founders Capital
VC Fund · Berlin, Berlin, Germany · 1 investments in South Africa Health Care startups

Over the past two decades, GFC have backed over five hundred entrepreneurs worldwide, e.g. Facebook, LinkedIn, Slack, and Away Travel.

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Investment focus

  • Industry: Financial Services, Software, FinTech
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Germany, United Kingdom

Investor stats

  • Total investments: 1119
  • Round size: Seed $1.2M–$8.8M; Pre-Seed $575k–$5M; Series A $5M–$30M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $2B in 2018

Portfolio highlights

  • Benford — Benford is a modern, licensed audit firm that provides technology-driven statutory audit services using its custom software, AuditOS.
  • Primo — A birdseye view of your IT.
  • sevDesk — Deutschlands beliebteste Buchhaltungssoftware: Rechnungen& Angebote erstellen, Buchhaltung erledigen, Kunden- &Lagerverwaltung u.v.m.
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Verge HealthTech Fund
VC Fund · Singapore, Central Region, Singapore · 1 investments in South Africa Health Care startups

We make early investments in global healthcare technology companies that address prevention, disease management and health system efficiency that are relevant to emerging Asia​We believe that innovation can happen anywhere, from the streets of Dhaka to the labs of Oxford, however without the right support network, these solutions might notscale, or find the best world-changing application. This is where we can help.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Pre-Seed, Series A
  • Geography: Estonia, Singapore, United States

Investor stats

  • Total investments: 30
  • Round size: Seed $500k–$4.7M; Pre-Seed $520k–$1M
  • Lead/follow: 57% lead, 43% follow
  • Last fund: Likely still investing — raised $250k in 2023

Portfolio highlights

  • THINKMD — THINKMD develops next-generation clinical assessment and data analytics platforms that transform point-of-care medicine by putting medically validated clinical assessment capability into the hands of non-healthcare professionals. This technology allows for the decentralization of healthcare delivery into communities and homes by pairing clinicalknowledge and Bayesian/pattern recognition algorithms with simple to use mobile technology. Its goal is to reinvent the healthcare delivery paradigm, reduce costs, and improve outcomes by improving healthcare access and care-seeking behavior while building a public health knowledge database.
  • Understanding Zoe — One calm home that remembers for you, for a whole life. Built in Australia for neurodivergent adults and families. Try free for 7 days.
  • Neuraworx Medical Technology — Neuraworx Medical Technology is a neurotechnology company developing first-in-class bioelectronic solutions for brain health.
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JPMorgan Chase & Co.
VC Fund · New York, New York, United States · 1 investments in South Africa Health Care startups, 30 in the past 12 months

JPMorgan Chase & Co. provides innovative financial solutions for consumers, small businesses, corporations, governments, and institutions. The firm is serving customers, helping small businesses, or putting its skills to work with partners, they strive to identify issues and propose solutions that will propel the future and strengthen both itsclients and communities.

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Investment focus

  • Industry: Financial Services, Software, Information Technology
  • Stage:Debt Financing, Post-IPO Debt, Grant
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 74
  • Round size: Grant $400k–$2.4M; Post-IPO Debt $20M–$5B; Debt Financing $10M–$800M
  • Lead/follow: 54% lead, 46% follow

Portfolio highlights

  • Castelion — Castelion is a venture-backed defense tech company applying modern hardware development and manufacturing processes to critical national security challenges, specifically to solve affordability, scale, and supply chain robustness. The company combines vertical integration, rapid iteration, and high-cadence testing to build hardware that isengineered from the ground up for scalable production.Castelion’s core offerings include solid-rocket motors, missile avionics, flight-control systems, seekers, and full strike-weapon assemblies, all designed for compatibility with existing military launch platforms.
  • Drax Group — Our purpose is to enable a zero carbon, lower cost energy future. Our ambition is to become carbon negative by 2030.
  • Castelion — We are a modern defense production company building the next generation of military hypersonic, vehicle, and strike systems to deter future wars.
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Technology Innovation Agency
VC Fund · Pretoria, NA - South Africa, South Africa · 1 investments in South Africa Health Care startups

WELCOME TO TIA Innovating Tomorrow Together Welcome to our agency - where ideas are nurtured, innovation is enabled , and impact is realised Through our funding, support programmes, and partnerships, we help innovators move from concept to impact. Whether you are an innovator or a partner, you are welcome here Funding Solutions SUPPORT PROGRAMMES

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Investment focus

  • Industry: Information Technology, Software, Electronics
  • Stage:Grant, Seed, Pre-Seed
  • Geography: South Africa

Investor stats

  • Total investments: 19
  • Round size: Seed $46k–$1.3M; Grant $25k–$1M; Pre-Seed $50k–$188k
  • Lead/follow: 79% lead, 21% follow

Portfolio highlights

  • Ann-Connect — Ann-Connect is an EdTech SaaS for learning, teaching, exams and assessments rolled into an all-in-one education platform.Founded in 2021 by Bonginkosi Mabaso, Nexa was born from a real problem: students missing exams and learning opportunities because of unreliable internet. Our mission is simple: make online education accessible to everystudent, regardless of connectivity or background. Today, Nexa is trusted by universities, training institutions, and professional bodies across South Africa, with partnerships that give access to more than 450,000 learners. One workspace. All your education tools: - Nexa ExamCore: Offline exam tool where students can access, write, and submit online exams even without internet. - Nexa Invigilator: Invigilation tool designed to monitor for online exams. - Nexa Invigilator Venue-based – Proctoring for physical/venue-based exams for schools, corporates & teams. - Nexa Room – Low-bandwidth video conferencing just like MS Teams but designed for teaching and learning, with AI-driven student engagement tracking. - Integrations – Seamless connection with Learning Management Systems (LMS), plagiarism checkers, and other education tools — all in one place. Recognised with awards from TIA, ABSA, and the Royal Academy of Engineering (UK), Nexa is shaping the future of global education by making it inclusive, resilient, and accessible everywhere. Ready to experience THE platform for inclusive learning? Visit ann-connect.com and join us in building education without limits.
  • Aviro Health — We believe that empowering and supporting people to manage their own health benefits everybody.We built the Aviro Pocket Clinic to support self-care and provide access to services. We give people what they need to perform important health checks like regular HIV self-testing and connect them to experts and services who can offer hands-on and supported care when needed.
  • All Weather Roads Engineering — All Weather Roads Engineering is a building material manufacturing firm also offering supply of construction material.
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Health Care VC funding in South Africa at a glance

Stats across 183 deals from 175 investors.

175
investors
in South Africa Health Care startups
183
deals
in South Africa Health Care startups
$405k
median round
in South Africa Health Care startups
49%
lead investors
lead at least one round
30%
Seed
most common funding stage

Access all 175 VC funds in South Africa Health Care startups.

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