Top 10 Medical Device Angel Investors in Japan (September 2026)

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Single Origin — Today, while platforms like Snowflake/GCP/AWS unlock insights and exploration, the volume of pipelines, the complexity of infrastructure, and the increasing cost of computing are overwhelming data teams. Single Origin helps data-driven organizations boost team productivity while realizing cloud cost savings. Our unique query optimizationplatform, operating between data warehouse and data tools/applications, automatically analyzes all of an organization's queries; identifies expensive and inefficient ones; then optimizes queries to be 10X simpler, faster and cheaper. We are the team that built and scaled uMetric at Uber, as well as other data infrastructure tools across snap, Reddit, Amazon, and Microsoft. More at https://docs.singleorigin.tech/
• Sandstone — Relationship management for legal departments.
• dweva.com — System Two Security offers a platform that combines AI agents and assistants to support detection engineering teams in processing intelligence, creating new detections, and managing detection libraries. The system enables users to draft and refine detections based on threat intelligence and coverage gaps.

Portfolio highlights

• Ezra AI — Ezra provides full-body MRI screening for potential early cancer and abnormalities in up to 13 organs. Book a scan today.
• Tribal — Tribal is a payments and financing platform using the latest emerging technologies to provide small and medium-sized businesses (SMBs) in emerging markets with better access to financial services. Tribal offers these SMBs access to modern payment methods like multi-currency physical and ​virtual business credit cards​, local and internationalwires, along with short-term financing, and a powerful ​spend management platform​ to track and control their expenses—all in one seamless interface. Tribal has raised from SoftBank Latin America Fund, QED Investors, BECO Capital, Stellar Development Foundation, and Coinbase Ventures. The company is also among an elite group of companies chosen as part of the Visa FinTech Fast Track program.
• Terraformation — Terraformation creates partnerships to scale reforestation with hardware, software, and knowledge based solutions.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.
• AndGAMER — AndGAMER is an eSports agency that develops custom controllers and gaming products for players.
• Freecracy — FreeC a platform that connects millions of employers and job seekers by utilizing intelligent matching technology that is powered by AI.

Portfolio highlights

• tayorie — tayorie is an automated messaging tool for transmitting sentiments and information in times of emergency.
• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.
• Amateras Space — Amateras Space is a startup driven by the mission to “expand the realm of human activity,” aiming to establish a next-generation spacesuit business by developing advanced, practical technologies that enable humans to work, explore, and thrive in space and other extreme environments.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Treinta — Treinta powers 7 million SMBs across the US and Latin America with simple finance, inventory, and sales tools.
• Ferveret — Ferveret develops liquid cooling technology for data centers and other infrastructure. Our company is backed by Y Combinator and MIT Media Lab's E14.
• Kriya AI is now Kalendar AI — Kalendar AI books new revenue on autopilot

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.