Top 30 Medical Angel Investors in Japan (June 2026)

Portfolio highlights

• AceRNA Technologies — AceRNA contributes to regenerative medicine and drug discovery through the discovery of novel miRNA functions. It began operation in April 2018, with its headquarters in Kyoto in Japan.
• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Flagellin — Flagellin is a pharmaceutical and medical industry.Development and sales of SaaS that supports sales and marketing of database and analysis services in the pharmaceutical and medical industries

Portfolio highlights

• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• Clear — Clear, Inc. operates sake subscription service “SAKELIFE".
• Cub McPaws — Buy comfortably fashionable kids clothes (4 - 12 years) online in India from Cub Mcpaws at best prices. Gorgeous dresses, jumpsuits, t-shirts, shirts & bottom wear for boys and girls | Free Shipping | COD
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.

Portfolio highlights

• Synflux — Synflux is a fashion lab comprising of fashion designers, software engineers & architects focused on fashion industry.
• AGRI SMILE — AGRI SMILE is a platform that focuses on sharing agricultural technology.
• EF Polymer — EF Polymer Private Limited providing 100% Organic and fully Biodegradable Super Absorbent Polymer cum Fertilizer to reduce Water and Fertilizer requirement for your plant. Let's grow organically.

Portfolio highlights

• Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.

Portfolio highlights

• SARAH — SARAH has been working on the planning and operation of the gourmet community app "SARAH", which operates a menu gourmet site "SARAH" that allows you to search for items you want to eat from menu-based posts.
• MTU — MTU offers medical security cloud services to medical organizations and delivers IT support, including the recent cyber harm to medical institutions, both online and offline.

Portfolio highlights

• CUICIN — Quickin is changing the travel experience with the digital transformation.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Magic Shields — Magic Shields is a manufacturer and seller of floors, nursing care, and welfare products.

Portfolio highlights

• Aiwell — Aiwell is a medical and health company that provides health information and the provision of health promotion and prevention services.

Portfolio highlights

• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
• Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
• MinD in a Device — MinD in a Device Co., Ltd. is a university-launched venture that aims to port human consciousness to devices (machines and computers) in the medium to long term based on long-term research results on consciousness. As the first step toward realization, we will evolve and deepen the "generation model" considered to be the source ofconsciousness, and promote the development of next-generation AI and social implementation.

Portfolio highlights

• Attelu — Attelu is a people analytics service that identifies, hires and retains active talent.
• Nose ID —
• Recipio — Recipio is an receipt management platform specialized in providing digital receipt solution. Their innovative digital receipt solution and breakthrough receipt-scanning technology.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Jinba —
• Wayco — Wayco offers AI software that automates client intake and case workflows for law firms using voice and referral intelligence processing.
• AgentMail — AgentMail provides an API-first email platform that enables AI agents to send, receive, and manage emails with automation and analytics.

Portfolio highlights

• M-Box — M-Box provides IT solutions to the pharmaceutical and healthcare industries and operates web services.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Willbox — Willbox is an international logistics company providing an international logistics digital platform for shippers and logistics companies. The company's platform "Giho" connects shippers and logistics companies (transportation, packaging, warehousing, customs clearance, etc.) with a direct contract. It visualizes the three elements of[lead time, money, and safety], which have been regarded as a black box, and supports comparative examination and decision making. Willbox digitizes the packing technique of wooden boxes and steel, mandatory for international logistics, and incorporated them into their system. Their mission is to solve the logistics issues focusing on the large cargo of industrial products.The company was founded in 2019 and is based in Yokohama-shi, Kanagawa.

Portfolio highlights

• Pleap — Pleap is a medical engineering company specializing in the development of AI and IoT-based technology solutions tailored for medical institutions. The company's product offerings include "medimo" which is an AI tool that automatically creates medical record manuscripts from medical audio.
• Ostance — Ostance is a group that moves the world in all kinds of entertainment.
• Conoris Technologies — Conoris Technologies is a staffing agency that offers security check support services for companies.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Plusmedi — Plus Medi is the developer of MyHospital, a medical care and management app offering personal health record (PHR) solutions.The app aims to help users by reducing the time they spend at the hospital or doctor's office. MyHospital also includes features like bills payment, medication management, and online paperwork.

Portfolio highlights

• Agatyca — Agatyca is an IT company that develops customized solutions to optimize payment system processes for organizations.

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• Epistra — Epistra accelerates research and development in life sciences.
• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.

Portfolio highlights

• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• Flyle — Flyle provides a cloud based platform for product management helping customers to improve productivity & creativity in product development.
• Reiwa Travel — Reiwa Trave is a digital travel agency intended that optimizes overseas travel. The company's platform uses online travel booking tools that provide digitalized contracts along with trip management, thereby enabling its customers' vacation and leisure experiences.
• Linkage — Linkage is a Online health support business and Online specific health guidance.

Portfolio highlights

• 3Sunny — 3Sunny is a company which helps in solve medical care issues so that everyone can feel at ease. The company solves the problems of people in the field while utilizing technology, and create a reliable society that will eventually reach the desired end. 3Sunny was founded in July 2016 and is headquartered in Tokyo, Japan.
• Contrea — Contrea develops and operates a tool that helps doctors explain the patient to be convinced and treated.

Portfolio highlights

• Next Innovation — Next Innovation is an online consulting provider for health care.
• Next Innovation — Next Innovation is an investment firm that focuses on the education sector.

Portfolio highlights

• Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
• Matsuri Technologies — matsuri technologies is a real estate tech company that provides solutions to support private property rentals. The company's products include m2m Systems, an Airbnb management platform that helps business operators to manage their accounts, communicate with guests, automate check-ins, offer customer service, and more.

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• RE — RE specializes in smartphone application design and development.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• MedPeer — MedPeer operates as a community site for doctors. MedPeer is a recruitment agency collective registration service.MedPeer operation of "MedPeer," a collective intelligence service/ community website for physicians.

Portfolio highlights

• Dofa — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Best Beer Japan — Best Beer Japan provides a barrel tracking software for craft beer and barrel sharing. The company was founded in 2018.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• Quatre — Quatre is a planning, operation and sales of all real promotion platform air catalog.
• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• Helpfeel — Our vision is to make saving, sharing, and exploring ideas as natural as breathing. On this journey we're humbled to be helping millions around the world from solo makers to university research labs, from gamers to pro designers, and large to small teams like ours.
• HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.