Top 50 Health Care Angel Investors in Japan in May 2026

Portfolio highlights

• M-Box — M-Box provides IT solutions to the pharmaceutical and healthcare industries and operates web services.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Willbox — Willbox is an international logistics company providing an international logistics digital platform for shippers and logistics companies. The company's platform "Giho" connects shippers and logistics companies (transportation, packaging, warehousing, customs clearance, etc.) with a direct contract. It visualizes the three elements of[lead time, money, and safety], which have been regarded as a black box, and supports comparative examination and decision making. Willbox digitizes the packing technique of wooden boxes and steel, mandatory for international logistics, and incorporated them into their system. Their mission is to solve the logistics issues focusing on the large cargo of industrial products.The company was founded in 2019 and is based in Yokohama-shi, Kanagawa.

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• RE — RE specializes in smartphone application design and development.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Go Visions — Go Visions engages in the edutainment tech for children and human resources services.
• Ai-Dounyu.com — Ai-Dounyu.com is a platform that helps organizations looking to integrate AI choose their ideal AI implementation partner for free.

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• Epistra — Epistra accelerates research and development in life sciences.
• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.

Portfolio highlights

• Onepair — Onepair is a job consulting and recruiting company. Onepair is to co-creating careers by talking about real-world ace with active ace.
• Strainer Co., Ltd. — Strainer Co., Ltd. is an information distribution platform that conveys corporate information centered on financial data. Although there are not a few media to deliver financial information, the company's strengths are strong to be easily viewed, including financial information of overseas companies.
• LAMILA — LAMILA develops system that improves the creation of retail stores.

Portfolio highlights

• Jizai — Jizai is a provider of artificial intelligence technology, offering AI solutions, software-as-a-service products powered by AI, and robots that utilize AI capabilities for businesses across various industries. The company focuses on generative AI, large language models (LLMs), and robotics, offering customizable AI platforms and automation tools.It also engages in AI consulting and research collaborations.
• Amptalk — Amptalk is a software development firm specializing in operating automatic transcription and analysis of online business negotiations.
• PeopleX — PeopleX encourages and assists employees in their professional development.

Portfolio highlights

• Cocoach — Cocoach provides online education service.
• Data Viz Lab — Data Viz Lab is a platform that offers data analysis, visualization consulting, and data human resource development support.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .

Portfolio highlights

• Dofa — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Best Beer Japan — Best Beer Japan provides a barrel tracking software for craft beer and barrel sharing. The company was founded in 2018.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• Vivid Garden — vivid garden is an Agriculture company.
• SAMURAI Security —

Portfolio highlights

• Revorf — Revorf analyzes data and develops AI-related to infectious diseases and healthcare.
• abillion — Find tips for plant-based food & products near you. Join the community to share reviews of restaurants & brands. Raise funds & drive sustainability!
• RIMM Sustainability — RIMM Sustainability provides a SaaS platform that enables companies of all sizes to optimise their sustainability management effort. It builds tools for sustainability management, reporting and optimisation.

Portfolio highlights

• JAPAN HEALTHCARE — Japan Healthcare is a healthcare start-up that works on the prevention of musculoskeletal diseases with environmentally-friendly preventive medicine . Japan Healthcare Build a preventive system for musculoskeletal diseases with environmentally-improving preventive medicine.
• Japan Healthcare Info — Japan Healthcase Info locates english-speaking doctors for you and makes appointments
• Legal Technology Japan — Legal Technology is into development of cloud-based research tool called 'Legal Library' using legal books.

Portfolio highlights

• iiba — Iiba is a geospatial platform that specializes in providing location information related to child-rearing.
• Plott — Plott producing youtube animation platform under Vision “Become a Content holder from YouTube”. In August 2019, the company name was changed from Fabo to Plott. Plott, the new company name, is derived from the plot that you make before writing novels, etc., and the idea that “I want to make content all the time” is put in the company name.
• Neighbor — Neighbor is a metaverse game developer that specializes in Fortnite.

Portfolio highlights

• CUICIN — Quickin is changing the travel experience with the digital transformation.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Magic Shields — Magic Shields is a manufacturer and seller of floors, nursing care, and welfare products.

Portfolio highlights

• Regain — Regain provides remote on-demand physical rehabilitation treatment solutions and video tutorials through the internet. It was launched by Hiroki Watanabe.
• ENDROLL — ENDROLL is a startup that develops and provides entertainment content using XR. Company Profile
• Autify — AI software testing company aimed at solving the challenges associated with automation testing. We are passionate about making software testing faster and easier, empowering companies to release faster and keep their applications stable.

Portfolio highlights

• Tanp — Gracia is an EC business and media business that provides coloring precious moments and enriching human connections.
• Syukatsu Labo — Syukatsu Labo is a leading company that solves various problems in an aging society.
• Somewhere — Somewhere is engaged in the travel and transportation business.

Portfolio highlights

• Favolist5 — Favolist5 is a software company that develops an abbreviated voice SNS based on web3 for personal media.
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.
• AnotherBall — AnotherBall is a blockchain startup that combines entertainment and blockchain.

Portfolio highlights

• Taliki — Taliki is a Coworking Space Operates Social Entrepreneurs Development Support for Intrepreneur Development.
• One Nova — One Nova (ワンノバ) is a lifestyle brand and online platform that offers a range of innerwear products, such as men's boxers.
• Vivid Garden — vivid garden is an Agriculture company.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• RIZAP — RIZAP is a chain of a private gym that offers fitness training and consulting services.
• Join Digital — Cloud-managed connectivity and workplace analytics enables businesses to optimize their workplace environment, capturing occupancy and indoor environmental quality (IEQ) data, and simplifying high-performance software-defined networking and WiFi experiences.
• Hippo Insurance — Hippo Insurance Services offers a different kind of home insurance, built from the ground up to provide a new standard of care and protection for homeowners. Our goal is to make homes safer and better protected so customers spend less time worrying about the burdens of homeownership and more time enjoying their homes and the life within. Harnessingreal-time data, smart home technology, and a growing suite of home services, we are creating the first integrated home protection platform. Hippo is headquartered in Palo Alto, California with offices in Austin and Dallas, Texas, and insurance products available to more than 80 percent of U.S. homeowners in 37 states. Hippo Insurance Services is a licensed property casualty insurance agent with products underwritten by various insurance companies.

Portfolio highlights

• Dofa — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Alliance Cloud — Alliance Cloud primarily engages in the Sales Tech and BtoB Sales Outsourcing Business.
• Cloud Franchise — Cloud Franchise is a cloud kitchen model that aims to maximize the kitchen occupancy rate of restaurants.

Portfolio highlights

• Cosic — KAREN, operated by ASHBERY, provides 3D interior coordination services according to personal preferences and lifestyle. Features of the service are the simplicity of use and the high quality of KAREN output. This is because users only have to upload photos of their rooms and pick three of their favorite interior photos on KAREN, and they arecommitted to securing the interior coordinator.The company was founded in 2018 and is based in Japan.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!

Portfolio highlights

• Kaimak — Kaymak is a recruitment platform that focuses on creating a recruitment website, planning a recruitment strategy, and managing candidates.
• Meetscare — Meetscare provides correct information and supports the self-awareness of all people involved in care. The company provides a wealth of information to ensure optimal care and create a mechanism for the realization. Users can make a telephone consultation and web diagnosis and search for free information using the system.Meetscare was founded on2016 and is headquartered in Arakawa, Tokyo.
• Driver Technologies — Driver Technologies is a cloud logistics platform provider. It provides a solution for driver matching and cargo vehicle demands.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• MiL Inc — Emerging products for healthcare food brands Producing food retailing and wholesale recipe development Restaurant management Catering media operation.

Portfolio highlights

• xCura — xCura alleviating pain and anxiety of people with the help of technology and product therapy VR.

Portfolio highlights

• Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
• Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
• MinD in a Device — MinD in a Device Co., Ltd. is a university-launched venture that aims to port human consciousness to devices (machines and computers) in the medium to long term based on long-term research results on consciousness. As the first step toward realization, we will evolve and deepen the "generation model" considered to be the source ofconsciousness, and promote the development of next-generation AI and social implementation.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• Flyle — Flyle provides a cloud based platform for product management helping customers to improve productivity & creativity in product development.
• Reiwa Travel — Reiwa Trave is a digital travel agency intended that optimizes overseas travel. The company's platform uses online travel booking tools that provide digitalized contracts along with trip management, thereby enabling its customers' vacation and leisure experiences.
• Linkage — Linkage is a Online health support business and Online specific health guidance.

Portfolio highlights

• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• Penmark — Penmark is a timetable management application that may also be used as a course management tool. The company's platform offers courses based on lesson data and lesson reviews that are unique to each university. Additionally, the in-class talk room generated for each class allows students to communicate with others who are taking the sameclass, allowing college students to take on challenges by thoroughly confronting each student and providing support that respects the individual's will.
• NoSchool — NoSchool is possible to ask a study teacher to a professional teacher who is working as a tutor or a private lecturer for free.
• Posiwill — Posiwill is a operating a career consultation service with job seekers billing type.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• tayorie — tayorie is an automated messaging tool for transmitting sentiments and information in times of emergency.
• Tooon — Tooon Inc. is a technology company that deals with development and operations of business management tools .
• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Brace — Brace is an online dental service provider that offers orthodontic treatment and electronic medical records.

Portfolio highlights

• Next Innovation — Next Innovation is an online consulting provider for health care.
• Next Innovation — Next Innovation is an investment firm that focuses on the education sector.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.
• Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.

Portfolio highlights

• Kaimak — Kaymak is a recruitment platform that focuses on creating a recruitment website, planning a recruitment strategy, and managing candidates.
• Recipio — Recipio is an receipt management platform specialized in providing digital receipt solution. Their innovative digital receipt solution and breakthrough receipt-scanning technology.
• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• LacuS — LacuS is a food technology company, develops and sells complete nutrition ice cream, provides nutritious food option for people of all ages.

Portfolio highlights

• xCura — xCura alleviating pain and anxiety of people with the help of technology and product therapy VR.

Portfolio highlights

• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• FiT — FiT encourages the use of information technology in fitness to address industrial concerns. We will build a highly sustainable fitness facility using a business model that allows consumers to easily use the gym without being burdened by price or procedures, while also allowing owners to build a very successful business with low running costs.
• Aoyama Arts — Aoyama Arts is an architecture and consulting company that develops design offices and supports land search and financing plans.
• Fabric Tokyo — FABRIC TOKYO is a Japanese startup provides a direct-to-consumer custom-made apparel brand. (former-company name Lifestyle Design Co., Ltd.). It enables customers to save their sizes, idea fabrics, and favorite designs, allowing them to make their original clothing later.FABRIC TOKYO was founded in 2012 by Yuichiro Mori and is based in Tokyo,Japan.

Portfolio highlights

• Ranimaru — Ranimaru is pet service providing company that offers pet sitting, care of your pet dog in events, professional course about pet sitting.

Portfolio highlights

• Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
• Matsuri Technologies — matsuri technologies is a real estate tech company that provides solutions to support private property rentals. The company's products include m2m Systems, an Airbnb management platform that helps business operators to manage their accounts, communicate with guests, automate check-ins, offer customer service, and more.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.
• Dots for — Welcome to Dots for Inc.
• Kisui Tech — Kisui Tech is an agricultural AI robotics company that help farmers for farming.

Portfolio highlights

• Sagri — Sagri is developing agriculture software for experienced farmers.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!
• Syukatsu Labo — Syukatsu Labo is a leading company that solves various problems in an aging society.

Portfolio highlights

• Zeigo — Zeigo by Schneider Electric provides sustainability software for efficient carbon reduction and supply chain decarbonization, aiming for a carbon-free future.
• Ecolectro — Ecolectro is solving the biggest challenges in making Green Hydrogen. Our alkaline ion-exchange membranes and polymers make clean fuel and decarbonize industry.
• Sniffer Robotics — Comprehensive methane emissions detection and quantification, advanced imagery and analytics; Sniffer Robotics provides advanced solutions that benefit the environment.

Portfolio highlights

• Clear — Clear, Inc. operates sake subscription service “SAKELIFE".
• Cub McPaws — Buy comfortably fashionable kids clothes (4 - 12 years) online in India from Cub Mcpaws at best prices. Gorgeous dresses, jumpsuits, t-shirts, shirts & bottom wear for boys and girls | Free Shipping | COD
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.
• ONE — One is a Japanese startup. It primarily creates and operates consumer apps, some of which have been sold to publicly traded Japanese corporations.This runs the BeReal exchange application "BeMatch."
• Nicoli — Nicoli is a company that creates content and advertisements that increase happy time for parents and children .