Top 50 Health Care Angel Investors in Japan (July 2026)

Portfolio highlights

• M-Box — M-Box provides IT solutions to the pharmaceutical and healthcare industries and operates web services.
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Willbox — Willbox is an international logistics company providing an international logistics digital platform for shippers and logistics companies. The company's platform "Giho" connects shippers and logistics companies (transportation, packaging, warehousing, customs clearance, etc.) with a direct contract. It visualizes the three elements of[lead time, money, and safety], which have been regarded as a black box, and supports comparative examination and decision making. Willbox digitizes the packing technique of wooden boxes and steel, mandatory for international logistics, and incorporated them into their system. Their mission is to solve the logistics issues focusing on the large cargo of industrial products.The company was founded in 2019 and is based in Yokohama-shi, Kanagawa.

Portfolio highlights

• Onepair — Onepair is a job consulting and recruiting company. Onepair is to co-creating careers by talking about real-world ace with active ace.
• Strainer Co., Ltd. — Strainer Co., Ltd. is an information distribution platform that conveys corporate information centered on financial data. Although there are not a few media to deliver financial information, the company's strengths are strong to be easily viewed, including financial information of overseas companies.
• LAMILA — LAMILA develops system that improves the creation of retail stores.

Portfolio highlights

• AceRNA Technologies — AceRNA contributes to regenerative medicine and drug discovery through the discovery of novel miRNA functions. It began operation in April 2018, with its headquarters in Kyoto in Japan.
• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Flagellin — Flagellin is a pharmaceutical and medical industry.Development and sales of SaaS that supports sales and marketing of database and analysis services in the pharmaceutical and medical industries

Portfolio highlights

• Now Do — Now Do provides online growth revolution platform.
• RE — RE specializes in smartphone application design and development.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• 3Sunny — 3Sunny is a company which helps in solve medical care issues so that everyone can feel at ease. The company solves the problems of people in the field while utilizing technology, and create a reliable society that will eventually reach the desired end. 3Sunny was founded in July 2016 and is headquartered in Tokyo, Japan.
• Contrea — Contrea develops and operates a tool that helps doctors explain the patient to be convinced and treated.
• HerLifeLab — HerLifeLab is healthcare consulting company working for women health and empowerment.

Portfolio highlights

• iiba — Iiba is a geospatial platform that specializes in providing location information related to child-rearing.
• Tohakusha — Tohakusha is a creative agency that offers design, production and sale of digital content and EC websites, and content creation services.
• Neighbor — Neighbor is a metaverse game developer that specializes in Fortnite.

Portfolio highlights

• Revorf — Revorf analyzes data and develops AI-related to infectious diseases and healthcare.
• Space Walker — SPACE WALKER specializes in design, manufacture and sale of peripheral components.
• RIMM Sustainability — RIMM Sustainability provides a SaaS platform that enables companies of all sizes to optimise their sustainability management effort. It builds tools for sustainability management, reporting and optimisation.

Portfolio highlights

• Dofa — Dofa aims to develop services that enrich the way of life and work of human resources that are active mainly in sales.
• Best Beer Japan — Best Beer Japan provides a barrel tracking software for craft beer and barrel sharing. The company was founded in 2018.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Jizai — Jizai is a provider of artificial intelligence technology, offering AI solutions, software-as-a-service products powered by AI, and robots that utilize AI capabilities for businesses across various industries. The company focuses on generative AI, large language models (LLMs), and robotics, offering customizable AI platforms and automation tools.It also engages in AI consulting and research collaborations.
• Amptalk — Amptalk is a software development firm specializing in operating automatic transcription and analysis of online business negotiations.
• Media Aid — Media Aid is an advertising agency that provides recruitment, marketing, web creation, and SNS management services

Portfolio highlights

• Aipass —
• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Yondemy — Yondemy is an online platform for children reading books.

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• AnotherBall — AnotherBall is a blockchain startup that combines entertainment and blockchain.
• SBX Corporation —

Portfolio highlights

• D-Chain — D-Chain offers services related to IT development and production in the Web3 and Web2 fields.
• Rayout — Rayout is a business consulting company that provides creative content development, recruitment videos, and web production services.
• CAREER BIJIN — Career bijin is a total support company.

Portfolio highlights

• JAPAN HEALTHCARE — Japan Healthcare is a healthcare start-up that works on the prevention of musculoskeletal diseases with environmentally-friendly preventive medicine . Japan Healthcare Build a preventive system for musculoskeletal diseases with environmentally-improving preventive medicine.
• Japan Healthcare Info — Japan Healthcase Info locates english-speaking doctors for you and makes appointments
• Legal Technology Japan — Legal Technology is into development of cloud-based research tool called 'Legal Library' using legal books.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• Vivid Garden — vivid garden is an Agriculture company.
• SAMURAI Security —

Portfolio highlights

• LacuS — LacuS is a food technology company, develops and sells complete nutrition ice cream, provides nutritious food option for people of all ages.

Portfolio highlights

• xCura — xCura alleviating pain and anxiety of people with the help of technology and product therapy VR.

Portfolio highlights

• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• FiT — FiT encourages the use of information technology in fitness to address industrial concerns. We will build a highly sustainable fitness facility using a business model that allows consumers to easily use the gym without being burdened by price or procedures, while also allowing owners to build a very successful business with low running costs.
• Aoyama Arts — Aoyama Arts is an architecture and consulting company that develops design offices and supports land search and financing plans.
• Fabric Tokyo — FABRIC TOKYO is a Japanese startup provides a direct-to-consumer custom-made apparel brand. (former-company name Lifestyle Design Co., Ltd.). It enables customers to save their sizes, idea fabrics, and favorite designs, allowing them to make their original clothing later.FABRIC TOKYO was founded in 2012 by Yuichiro Mori and is based in Tokyo,Japan.

Portfolio highlights

• Ranimaru — Ranimaru is pet service providing company that offers pet sitting, care of your pet dog in events, professional course about pet sitting.

Portfolio highlights

• Heartseed — Heartseed has set a mission to “open the door to heart disease treatment with regenerative medicine” and is working toward the day-to-day clinical application of myocardial regenerative medicine.
• Matsuri Technologies — matsuri technologies is a real estate tech company that provides solutions to support private property rentals. The company's products include m2m Systems, an Airbnb management platform that helps business operators to manage their accounts, communicate with guests, automate check-ins, offer customer service, and more.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.

Portfolio highlights

• BionicM — BionicM develops high-performance robot prostheses that enhance mobility for people with disabilities.BionicM has been conducting research on innovative technologies since 2015 at the University of Tokyo's Information Systems Engineering Laboratory (JSK) under the guidance of Professor Inaba and utilizing the world's most advancedrobotics research. In 2016, we were adopted by the Japan Science and Technology Agency as part of "Program for Creating STart-ups from Advanced Research and Technology" (START), and in 2018, the company was established as a joint-stock company.
• Dots for — Welcome to Dots for Inc.
• Kisui Tech — Kisui Tech is an agricultural AI robotics company that help farmers for farming.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.
• ONE — One is a Japanese startup. It primarily creates and operates consumer apps, some of which have been sold to publicly traded Japanese corporations.This runs the BeReal exchange application "BeMatch."
• Nicoli — Nicoli is a company that creates content and advertisements that increase happy time for parents and children .

Portfolio highlights

• Opt Fit — Opt Fit is a fitness industry that provides fitness, wellness and health-care services.
• FiT — FiT encourages the use of information technology in fitness to address industrial concerns. We will build a highly sustainable fitness facility using a business model that allows consumers to easily use the gym without being burdened by price or procedures, while also allowing owners to build a very successful business with low running costs.
• Voxela — Voxels is an AI powered platform on a mission to reinvent caregiving by making incident detection intelligent and actionable.

Portfolio highlights

• AgeWell Japan — Age Well Japan is a conference and festival aimed at understanding Japan's super-aged society and defining new values for the future. The purpose of the gathering is to bring together young people and the elderly to exchange ideas.

Portfolio highlights

• SARAH — SARAH has been working on the planning and operation of the gourmet community app "SARAH", which operates a menu gourmet site "SARAH" that allows you to search for items you want to eat from menu-based posts.
• MTU — MTU offers medical security cloud services to medical organizations and delivers IT support, including the recent cyber harm to medical institutions, both online and offline.

Portfolio highlights

• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• Pleap — Pleap is a medical engineering company specializing in the development of AI and IoT-based technology solutions tailored for medical institutions. The company's product offerings include "medimo" which is an AI tool that automatically creates medical record manuscripts from medical audio.
• AGRI SMILE — AGRI SMILE is a platform that focuses on sharing agricultural technology.
• Conoris Technologies — Conoris Technologies is a staffing agency that offers security check support services for companies.

Portfolio highlights

• Astroscale — Astroscale is one of the few companies in the world proposing to aid in the removal of orbital debris through the provision of End of Life (EOL) and Active Debris Removal (ADR) services. In addition to providing a technical solution, Astroscale is helping to define the business case for this service and are working with national space agencies,international institutions, non-profit organizations, insurance companies and satellite operators to develop norms, regulations and incentives that contribute to the responsible use of space.
• SMS — The corporate website of SMS Co., Ltd. We disclose a wide range of information, including company overview, investor relations, and sustainability.

Portfolio highlights

• Pleap — Pleap is a medical engineering company specializing in the development of AI and IoT-based technology solutions tailored for medical institutions. The company's product offerings include "medimo" which is an AI tool that automatically creates medical record manuscripts from medical audio.
• Ostance — Ostance is a group that moves the world in all kinds of entertainment.
• Conoris Technologies — Conoris Technologies is a staffing agency that offers security check support services for companies.

Portfolio highlights

• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• MIL — MIL is a marketing company it can be used for a wide range of video marketing such as video commerce , O2O measures , recruitment videos , and landing videos.
• Now Do — Now Do provides online growth revolution platform.
• Saurus Japan —

Portfolio highlights

• Mairu Tech — Mairu tech that enables traveling by private ambulance and welfare taxi more convenient.

Portfolio highlights

• Agatyca — Agatyca is an IT company that develops customized solutions to optimize payment system processes for organizations.

Portfolio highlights

• Sorcerer — Sorcerer builds weather balloons that fly for over six months, collecting 1000x more data per dollar and reaching previously inaccessible regions
• Oway — Join thousands that ship freight instantly with Oway's rideshare freight platform and save up to 50% on your shipping. Pickups in just 1 hour, delivered overnight with insurance and tracking included on all shipments.
• Vybe — Vybe is a software company that provides pre-built integrations and AI tools for users to develop and launch internal AI-powered apps.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• Favolist5 — Favolist5 is a software company that develops an abbreviated voice SNS based on web3 for personal media.
• Smartround — Smartround is a specialized finance management platform for startups and their investors. For start-ups, for entrepreneurs who are not familiar with finance, simply enter the necessary information according to the guide, prepare appropriate financing round, and prepare a function that can simulate and execute a capital increase. Support informationsharing and communication with shareholders even after the capital increase.
• AnotherBall — AnotherBall is a blockchain startup that combines entertainment and blockchain.

Portfolio highlights

• Cosic — KAREN, operated by ASHBERY, provides 3D interior coordination services according to personal preferences and lifestyle. Features of the service are the simplicity of use and the high quality of KAREN output. This is because users only have to upload photos of their rooms and pick three of their favorite interior photos on KAREN, and they arecommitted to securing the interior coordinator.The company was founded in 2018 and is based in Japan.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!

Portfolio highlights

• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.

Portfolio highlights

• Zeigo — Zeigo by Schneider Electric provides sustainability software for efficient carbon reduction and supply chain decarbonization, aiming for a carbon-free future.
• RootWave — RootWave is an electronics company that develops tools that kill weeds it enables farmers to control weeds on their farm. Its technology is an alternative substitute for herbicides and other weed control chemicals. The company was founded in 2012 and headquartered in Warwickshire, United Kingdom.
• CoCooking — CoCooking uses food and cooking to create ample opportunity for dialogue and thought, fostering creativity, diversity, and well-being of individuals and communities.

Portfolio highlights

• Elaly — Elaly Technology makes life better for people around the world.We aim to make the value of money and the experience gained from it flatter.As many people as possible will use technology to realize a happier life, independent of the money economy.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!
• DariaMe — DariaMe is a web media planning, development and operation, planning and production of various contents, online consultation service.

Portfolio highlights

• HANOWA — HANAWA is a matching platform between freelance dental hygienists and dental clinics.
• Tooon — Tooon Inc. is a technology company that deals with development and operations of business management tools .
• Address — ADDress is a provider of co-living spaces in both urban and rural areas, enabling people to live in a range of luxurious residences at fixed prices.

Portfolio highlights

• Taliki — Taliki is a Coworking Space Operates Social Entrepreneurs Development Support for Intrepreneur Development.
• One Nova — One Nova (ワンノバ) is a lifestyle brand and online platform that offers a range of innerwear products, such as men's boxers.
• Vivid Garden — vivid garden is an Agriculture company.

Portfolio highlights

• Neith — Neith is a apparel manufacturer, seller and a whoelseller of water absorbing bralette, lingerie and shorts for women.
• WARC — WARC provides hands-on support for business management departments as well as mergers and acquisition advisory services.
• Vitalogue Health — Vitalogue Health offers Canvas, a home-based hormone testing service for women.

Portfolio highlights

• RIZAP — RIZAP is a chain of a private gym that offers fitness training and consulting services.
• Hippo Insurance — Hippo Insurance Services offers a different kind of home insurance, built from the ground up to provide a new standard of care and protection for homeowners. Our goal is to make homes safer and better protected so customers spend less time worrying about the burdens of homeownership and more time enjoying their homes and the life within. Harnessingreal-time data, smart home technology, and a growing suite of home services, we are creating the first integrated home protection platform. Hippo is headquartered in Palo Alto, California with offices in Austin and Dallas, Texas, and insurance products available to more than 80 percent of U.S. homeowners in 37 states. Hippo Insurance Services is a licensed property casualty insurance agent with products underwritten by various insurance companies.
• Jupiter Intelligence — The Trusted Leader in Climate Risk Analytics. Learn about our best-in-science solutions.

Portfolio highlights

• Kaimak — Kaymak is a recruitment platform that focuses on creating a recruitment website, planning a recruitment strategy, and managing candidates.
• Meetscare — Meetscare provides correct information and supports the self-awareness of all people involved in care. The company provides a wealth of information to ensure optimal care and create a mechanism for the realization. Users can make a telephone consultation and web diagnosis and search for free information using the system.Meetscare was founded on2016 and is headquartered in Arakawa, Tokyo.
• Driver Technologies — Driver Technologies is a cloud logistics platform provider. It provides a solution for driver matching and cargo vehicle demands.

Portfolio highlights

• Sagri — Sagri is developing agriculture software for experienced farmers.
• SOELU — SOELU is an online yoga studio where you can take lessons from popular instructors at home for women only. Even if you can't attend yoga classes, the instructor will guide you through the screen, so you can continue online at home!
• Syukatsu Labo — Syukatsu Labo is a leading company that solves various problems in an aging society.

Portfolio highlights

• BeatFit — BeatFit is a fitness-tech startup based in Japan.
• CAN EAT —
• Progrit — PROGRIT is an English-related media management company.

Portfolio highlights

• MedPeer — MedPeer operates as a community site for doctors. MedPeer is a recruitment agency collective registration service.MedPeer operation of "MedPeer," a collective intelligence service/ community website for physicians.

Portfolio highlights

• Quatre — Quatre is a planning, operation and sales of all real promotion platform air catalog.
• KURASERU — KURASERU is a Japanese startup company that provides facility matching service for medical social workers and care managers.