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Top 10 Biotech Angel Investors in Japan (June 2026)

The most active angel investors investing in Japan Biotech startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in Japan Biotech startup companies. Find investors to raise a Pre-Seed, Seed or Angel round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Koki Yabu
Angel
2 Japan Angel, Pre-Seed Content, Finance, Data Mining $1.7M–$3M
Hidetoshi Takano
Angel
1 Japan, United States Seed, Angel Internet, Information Technology, Content $4.3M–$30M
Hirofumi Miki
Angel
1 Japan Seed, Angel, Pre-Seed Content, Internet, Software $2.8M–$16M
Hiroaki Kitano
Angel
1 Japan, United States Seed, Angel, Debt Financing Health Care, Fitness, Medical $3.3M–$43M
Yasunori Kaneko
Angel
1 Japan Seed Biotechnology
Kenshin Fujiwara
Angel
1 Japan Seed, Series A Mobile, Medical, Software
Yutaka Matsuo
Angel
1 Japan Seed, Angel Artificial Intelligence, SaaS, Robotics
Shoji Okamoto
Angel
1 Japan Seed Lifestyle, Life Science, Service Industry
Yuriko Minami
Angel
1 Japan Series A, Seed, Series B Medical, Biotechnology, SNS
Kamata Tomihisa
Angel
1 Japan, United States Seed, Angel Fitness, Medical, Genetics
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Investor list

Koki Yabu
Angel · Tokyo, Tokyo, Japan · 2 investments in Japan Biotech startups

Koki Yabu is Founder, President & CEO at Mobcast inc.

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Investment focus

  • Industry: Content, Finance, Data Mining
  • Stage:Angel, Pre-Seed
  • Geography: Japan

Investor stats

  • Total investments: 3
  • Round size: Angel $1.7M–$3M
  • Lead/follow: 33% lead, 67% follow

Portfolio highlights

  • Mobcast Group — mobcast is a sports entertainment company that operates a mobile entertainment platform for smartphones and feature phones. It supports customers with social game and social media services. The company was founded in 2009 and is based in Tokyo, Japan. Currently, it operates as a subsidiary of mobcast Inc.
  • SmartApp Japan — Smart Apps is a developer of a blockchain services application designed for smartphones. The company's application uses cryptocurrency technology to offer token issuance, initial coin offering and dApps design support, providing a launchpad for start-up blockchain-related businesses.
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Hidetoshi Takano
Angel · Tokyo, Tokyo, Japan · 1 investments in Japan Biotech startups

Joined Intelligence in 1999. Established Key Players Inc. in 2005. Consultation with more than 3,000 managers and career counseling for more than 10,000 individuals. In addition, we have invested in more than 55 outside directors, advisors and angels in Silicon Valley and Bangladesh in Japan. Over 100 lectures on careers, entrepreneurship andstartups.

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Investment focus

  • Industry: Internet, Information Technology, Content
  • Stage:Seed, Angel
  • Geography: Japan, United States

Investor stats

  • Total investments: 42
  • Round size: Seed $5.7M–$21M; Angel $4.3M–$30M
  • Lead/follow: 2% lead, 98% follow

Portfolio highlights

  • Cocoach — Cocoach provides online education service.
  • Data Viz Lab — Data Viz Lab is a platform that offers data analysis, visualization consulting, and data human resource development support.
  • ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .
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Hirofumi Miki
Angel · Shibuya, Kanagawa, Japan · 1 investments in Japan Biotech startups

After JTB Co., Ltd. and CYBIRD Co., Ltd. as an initial member of Glee Co., Ltd. is responsible for business development. Currently, he is mainly engaged in venture support in the Internet area, investing in venture and venture capital, and served as management advisor for dozens of companies. Hands-on business development, growth strategydevelopment, financing advice, HR organization design support, partner referral and Recruit Support. He is also engaged in business support for ventures in the healthcare and university venture fields. He served as Digital Health Meetup Advisor, NEDOTCP Mentor and Future 2016 Mentor.

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Investment focus

  • Industry: Content, Internet, Software
  • Stage:Seed, Angel, Pre-Seed
  • Geography: Japan

Investor stats

  • Total investments: 27
  • Round size: Seed $2.8M–$16M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • AceRNA Technologies — AceRNA contributes to regenerative medicine and drug discovery through the discovery of novel miRNA functions. It began operation in April 2018, with its headquarters in Kyoto in Japan.
  • Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
  • Go Visions — Go Visions engages in the edutainment tech for children and human resources services.
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Hiroaki Kitano
Angel · 1 investments in Japan Biotech startups

Hiroaki Kitano is the SVP at Softbank Mobile. He attended Waseda University.

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Investment focus

  • Industry: Health Care, Fitness, Medical
  • Stage:Seed, Angel, Debt Financing
  • Geography: Japan, United States

Investor stats

  • Total investments: 6
  • Round size: Seed $3.3M–$43M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
  • Epistra — Epistra accelerates research and development in life sciences.
  • Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
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Yasunori Kaneko
Angel · San Francisco Bay Area, California, United States · 1 investments in Japan Biotech startups

Yasunori has been involved in managing and financing US life sciences companies since 1981. He began his career at Genentech (NYSE: DNA), where he spearheaded its business development activities for the first several years. He was then Project Manager for the launch of Protropin (human growth hormone), the first product marketed by Genentech. In1987, he became head of corporate finance in the investment banking division of Paribas Capital Markets LTD in Tokyo, where he helped finance Japanese government agencies, municipalities and corporations in the Euro market. He also helped numerous life sciences companies raise capital. He then became Senior Vice President and CFO of Isis Pharmaceuticals (NASDAQ: ISIS), which went public during his tenure there. In 1992, he was recruited to be the original business executive at Tularik (acquired by Amgen in 2004), where at various times he was CFO and VP-Business Development until its public offering in 1999. He served on the board of LeukoSite until its merger with Millennium Pharmaceuticals (NASDAQ: MLNM) in 1999. He received an undergraduate degree from Keio University in Tokyo, a medical degree from Keio University School of Medicine, and an M.B.A. from Stanford Business School. He joined Skyline in 1999. He committed to golf several years ago after an unfortunate heading incident at a team reunion for his junior All-Star soccer team.

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Investment focus

  • Industry: Biotechnology
  • Stage:Seed
  • Geography: Japan

Investor stats

  • Total investments: 1
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Logomix — Logomix Inc is a mammalian cellular genome architect startup. Logomix proprietary platform, Geno-Writing™, technology integrates large-scale (Mb) human genome-writing technologies and providing genetically architected versatile human cells and/or downsized cells and microbes for drug development and cell & gene therapy area.Majority ofthe cell engineering companies are currently focused on optimization of gene clusters by automatic high throughput system however, Logomix’s Geno-Writing™ provides the required tools for dealing with mammalian or complex genomes. Logomix works with partners by providing new biology-based solutions to co-create business and social values on Geno-Writing™ platform Current Focus Area includes: 1. Human Health & Therapeutics 2. Biomaterials & Chemicals 3. Agriculture & EnvironmentLogomix has 11 ongoing collaborative research partnerships. Currently Logomix is specifically looking for industry partners to address unmet needs in neurodegenerative disease areas.
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Kenshin Fujiwara
Angel · Kyoto, Kyoto, Japan · 1 investments in Japan Biotech startups

Kenshin is a CEO at Hacarus Inc., a healthcare technology startup based in Kyoto, Japan.He co-founded several tech startups with 2 exits in the past 15 years. His first career started as an engineer at Sony Computer Entertainment and worked on PlayStation development projects. HIs fist startup was acquired by Japanese public company, and thesecond startup was sold to the US company.Born in 1976. He holds a Computer Science degree from California State University. He loves mountain hiking and currently living in Kyoto Japan with his wife and family.

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Investment focus

  • Industry: Mobile, Medical, Software
  • Stage:Seed, Series A
  • Geography: Japan

Investor stats

  • Total investments: 2
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Helpfeel — Our vision is to make saving, sharing, and exploring ideas as natural as breathing. On this journey we're humbled to be helping millions around the world from solo makers to university research labs, from gamers to pro designers, and large to small teams like ours.
  • HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
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Yutaka Matsuo
Angel · Tokyo, Tokyo, Japan · 1 investments in Japan Biotech startups

1997 Graduated from Tokyo University, Department of Electronic and Information Engineering. In 2002, he completed the doctoral program at the same graduate school. Ph.D. (Engineering) He was a researcher at the Institute of Industrial Science and Technology since the same year. After working as a visiting researcher at Stanford University in August2005, Associate Professor of Technology Management Strategy, Institute of Research, Graduate School of Engineering, University of Tokyo in 2007. Co-Representative, Associate Professor, Global Consumption Intelligence Donation Course, Department of Technology Management Strategy, Graduate School of Engineering, Tokyo University. Professor from 2019, Graduate School of Engineering, Tokyo University of Engineering, Department of Technology Management Strategy. He specializes in artificial intelligence, web mining, big data analytics. The Society of Artificial Intelligence received the Paper Award (2002), the 20th Anniversary Project Award (2006), the Field Innovation Award (2011), and the Merit Award (2013). At the Society of Artificial Intelligence, he has been a student editorial committee and an editorial committee, and vice chair/director since 2010. Chairman of Ethics from 2014 to 2018. Chairman of Japan Deep Learning Association since 2017.

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Investment focus

  • Industry: Artificial Intelligence, SaaS, Robotics
  • Stage:Seed, Angel
  • Geography: Japan

Investor stats

  • Total investments: 6
  • Lead/follow: 17% lead, 83% follow

Portfolio highlights

  • Jizai — Jizai is a provider of artificial intelligence technology, offering AI solutions, software-as-a-service products powered by AI, and robots that utilize AI capabilities for businesses across various industries. The company focuses on generative AI, large language models (LLMs), and robotics, offering customizable AI platforms and automation tools.It also engages in AI consulting and research collaborations.
  • MemoriaPet — Memoria Pet operated by Next Paradigm 2 Co., Ltd. Creates full-color 3D-printed pet figurines from a single uploaded photo. Uses AI to generate 3D models, followed by full-color 3D printing.
  • Tsunagari AI — Tsunagari specializes in developing and providing AI-powered consultation services tailored for local governments, aiming to enhance administrative efficiency, support citizen engagement, and streamline public service delivery.
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Shoji Okamoto
Angel · 1 investments in Japan Biotech startups

Shoji Okamoto is the President of Mirai Works.

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Investment focus

  • Industry: Lifestyle, Life Science, Service Industry
  • Stage:Seed
  • Geography: Japan

Investor stats

  • Total investments: 2
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Monoun — Mono.un provides users with opportunities to meet authors and collaborate on tales and specializes in bringing exciting experiences full of stories of Japanese culture to the world.
  • Memory Lab — Memory Lab is a research laboratory that offers AI paper analysis and development solutions.
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Yuriko Minami
Angel · 1 investments in Japan Biotech startups

Yuriko Minami is the Capitalist at Mirai Sozo Organization.

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Investment focus

  • Industry: Medical, Biotechnology, SNS
  • Stage:Series A, Seed, Series B
  • Geography: Japan

Investor stats

  • Total investments: 5
  • Lead/follow: 20% lead, 80% follow

Portfolio highlights

  • digzyme — Digzyme is a research and development platform for creating, discovering, and evaluating new enzyme-catalyzed reactions by bioinformatics.
  • Varinos — Varinos is a clinical laboratory contract analysis company that is a partner of medical institutions. Varinos provides genomic testing development and contract analysis services using the latest technology, the next-generation sequencer.
  • Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
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Kamata Tomihisa
Angel · Tokyo, Tokyo, Japan · 1 investments in Japan Biotech startups

Dr. Kamada earned his Ph.D. at the University of Tokyo. In 1984, he pursued his journey to establish his own business that focused on information appliances and mobile software, namely ACCESS Co., Ltd.. With great success, the company entered the Tokyo Stock Exchange Mothers Market in 2001. He left ACCESS Co., Ltd. in 2011, and founded TomyK Ltd.in 2012 where he supports startups possessing revolutionary business ideas that revitalize the Japanese economy.

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Investment focus

  • Industry: Fitness, Medical, Genetics
  • Stage:Seed, Angel
  • Geography: Japan, United States

Investor stats

  • Total investments: 3
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Activaid — Activaid owns and operates a social data platform for patients with inflammatory bowel disease. It allows patients to support and exchange information within the patient community with the same disease; provide information necessary for new drug development and matching to clinical trials that suits them; and improve medical treatment. YasuakiHasebe founded Activaid in 2018. It has its headquarters in Tokyo in Japan.
  • Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.
  • MinD in a Device — MinD in a Device Co., Ltd. is a university-launched venture that aims to port human consciousness to devices (machines and computers) in the medium to long term based on long-term research results on consciousness. As the first step toward realization, we will evolve and deepen the "generation model" considered to be the source ofconsciousness, and promote the development of next-generation AI and social implementation.
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